Ọgwụ Glidiab MV: ntuziaka maka ojiji, nyocha

Gliclazide bụ ọgwụ hypoglycemic ọgwụ metụtara na usoro sulfonylureas Ọgbọ nke abụọ. A na-eme ihe nke ọgwụ ahụ ka ọ rụọ ọrụ nke mkpụrụ ndụ sel pancreasna-arụpụta insulin, mụbaa ịba uru n’akwara anụ ahụ na ya, mụbaa mmetụta glucose insulin na mkpali nke ọrụ intracellular glycogen synthetase na akwara anụ ahụ. Ọgwụ na -ebelata oge site na ntinye nri rue mbido mmepụta insulinna-ebelata postprandial glucose, na-eweghachi mmalite (mbụ) elu insulin secretion (n’adịghị ka ọgwụ ndị ọzọ sulfonylureasna-arụ ọrụ na ngalaba nke abụọ).

Na mgbakwunye na ịhazi metabolism metabolism gliclazide na-emeziwanye microcirculationsite na ibelata nchịkọta platelet na adhesion, normalization nke vaskụla permeability, mweghachi nke physiological usoro parietal fibrinolysis.

Usoro ọgwụgwọ glidiab na-ebelata mmetụ vaskụla adrenalinena - egbochi imepụta atherosclerosis na microthrombosis. Na-egbochi ịga n'ihu na-abụghị proliferative (ndabere) ọrịa mamịrị retinopathy. Site na ọgwụgwọ ogologo oge, a na-ahụ mbelata dị ukwuu proteinuriana-etolite na ndabereọrịa mamịrị nephropathy.

Thenara ọgwụ ahụ, n'ihi nsonaazụ ya na mbido mbụ insulin insulin, adịghị eso ya na-aba uru ma na-akwado ya ka ọbelata ndị ọrịa buru ibu, ma ọ bụrụ na o kwesịrị usoro ọgwụgwọ nri.

Nchịkwa ọnụ gliclazide na - eduga na nracha ya zuru oke na ngwangwa nri. TCmax na ọbara ọbara 4 awa (maka mbadamba MV - awa 6-12). Indmịnye protein ndị dị na plasma bụ ọkwa 90-95%. Mgbanwe Metabolic na-adị na imeju na mwepụta nke ngwaahịa anaghị arụ ọrụ metabolism. T1 / 2 bụ awa 8-11 (maka mbadamba MV - awa 16). Ferencedị ntinye metabolites Ọ bụ akụrụ na-arụ ọrụ (ihe dị ka 70%), yana eriri afọ (12%). Ihe dị ka 1% gliclazide na-agbanwegharị na mmamịrị.

Ihe ngosi maka ojiji

Glidiab egosiputara ụdị shuga 2 (NIDDM, ọrịa shuga na-abụghị insulin) na nke nke ya usoro ọgwụgwọ nri na igbu mmadummega ahụ ihe isi ike na-adịghị agafe agafe ma ọ bụrụ na ha anaghị arụ ọrụ n'oge gara aga.

Ihe Glidiab machiri ihe eji eme ihe bu:

• ọrịa mamịrị ketoacidosis,
• inye ara,
• ụdị shuga 1,
• mamịrị precom /Coma,
• ọrịa ọnya imeju/akụrụ,
• hyperosmolar coma,
• leukopenia,
• ọnọdụ mgbu, na iji iji ya insulingụnyere mmerụ ahụ, ịwa ahụburu ibu na-agba ọkụ,
• paresis nke afo,
• nke afọ ime,
• mgbochi ime eriri afọ,
• pathologies soro malabsorption nri na ịkpụ akpụ hypoglycemia (gụnyere ọrịa na-efe efe)
• nkeonwe hypersensitivity ka gliclazide ma ọ bụ ọgwụ ndị ọzọ
• na nwata.

Nsonaazụ

Nsonaazụ kachasị emetụta ma dị njọ nke Glidiab bụ hypoglycemia, ọtụtụ oge na-esite na mmebi nke usoro usoro onunu ogwu na ezughi oke usoro ọgwụgwọ nri. Ihe omumu ihe omimi a bu ihe di iche iche ma gosiputa onwe ya. isi ọwụwaagụụ ike gwụrụna mberede adịghị ikeinattention nchegbu, ike ikemgbakasị ahụ ọnọdụ ịda mbangwa ngwa mmeghachi omume, enweghi ike itinye uche, mmebi anyaenweghi enyemaka aphasiansogbu mmetụta uche ịma jijiji, anya ntughari, delirium, ọnwụ nke njide onwe onye, mmasiọnwụ nke mmụọ hyperomniaiku ume ọsụsọ, bradycardia.

Effectszọ nke abụọ kachasị dị egwu metụtara ọgwụgwọ Glidiab bụ nke a na-ahụta na ọ bụ mmetụta ọjọọ nke a na-ahụ na ọnya afọ, nke a na-ekwupụta dyspepsia (ọgbụgbọogo epigastric na afọ ọsịsa), imebi iwu ọrụ ịba ọcha n'anya (mụbaa ọrụtransaminase imeju, jalestice cholestatic), anorexia (n'ihe banyere ị ofụ ọgwụ na ihe oriri, oke anorexia mbelata).

Nwere ike ịmalite Ngosipụta nfụkasịtumadi na-ebilite na urticaria, maculopapular rash na akpụkpọ anụ?.

Mgbe ụfọdụ, hụrụ mgbe e guzobere ya leukopenia, thrombocytopenia na anaemia.

Glidiab, ntuziaka maka ojiji

A na-eme nhọrọ nke usoro onunu ogwu nke Glidiab ọgwụ n'otu n'otu dabere na ngosipụta ụlọ ọgwụ NIDDM na ọkwa glycemia, nke a tụrụ n ’afọ efu, yana mgbe awa 2 gachara.

Na mbu, a na-atụ aro iri nri nke 1 Glidiab 80 mg mbadamba kwa ụbọchị ma ọ bụ mbadamba 1st Glidiab MV 30 mg. Nkezi onwa kwa ubochi bu 160 mg na 60 mg, nke kachasi bu 320 mg na 120 mg, dika ntabi anya, maka mbadamba na mbadamba MV. A na-ewere mbadamba 80 mg Mgbakọ 30-60 tupu nri ugboro abụọ na awa 24 (n'ụtụtụ na mgbede). Mpekere MV 30 mg na-egosi ka a ga-ewere ya otu ụtụtụ kwa ụbọchị mgbe nri ụtụtụ. Enwere ike ịbawanye usoro onyonyo ọ bụla ma ọ dịkarịa ala ụbọchị 14.

Ndị okenye na ndị ọrịa nwere okenye ọrịa akụrụ (ya na CC 15-80 ml / min) anaghị achọ idozi dose.

Dodoụbiga ya ókè

Ọ bụrụ na ị doụbiga mmanya ókè gliclazide hụrụ mmepe hypoglycemiamgbe ụfọdụ na-eruhypoglycemic coma.

N'ọnọdụ nke ngosipụta nke ị ofụbiga mmanya ókè na-eme ka onye ọrịa mara, ọ kwesịrị ị needsụ mmiri ozugbo mmiri shuga ma obu glucose (dextrose) Na ọnọdụ amaghị onye ọrịa ahụ, a na-egosipụta nchịkwa ọgbụgba nke usoro ahụ Dextrose (40%) ma ọ bụ ntụtụ IM Glucagon (1-2 mg). N’ọdịnihu, n’iji ụfọdụ ikesa ọnọdụ ahụ, onye ọrịa kwesịrị iri nri nwere nnukwu afọ ojuju carbohydrates, maka nzube nke ịdọ aka ná ntị nlọghachi nke hypoglycemia.

Mmekorita

A na-achọpụta mbelata nke ịdị hypoglycemic nke Glidiab ọ bụrụ na ojiji ejiri ya na ya glucocorticoids, mgbochi egonnabata (Terbutaline, Epinephrine, Ritodrin, Clonidine, Salbutamol), ndị na-emegide calcium, nnu nke lithium, nicotinic acid, thiazide diureticscarbonic anhydrase inhibitors (Diacarb), Chlortalidone, Triamteren, Chlorpromazine, Furosemide, Asparaginase, Danazol, Baclofen, Diazoxide, Rifampicin, Morphine, Isoniazid, Glucagon, Phenytoin, homonụ thyroid gland na estrogen (gụnyere ogwu gboro ya).

A na-achọpụta mmụba na ọrụ hypoglycemic nke Glidiab na ojiji ya na ọgwụ antifungal (Fluconazole, Miconazole), ACE inhibitors (Enalapril, Captopril), H2-igbochi (Cimetidine), fibrates (Bezafibrat, Clofibrate), NSAIDs (Indomethacin, Phenylbutazone, Diclofenac), ọgwụ ndị na-egbu egbu, ọgwụ mgbochi (Etionamide), anticoagulants na-apụbeghị iche, Ndị na-egbochi yaanabolic steroid CyclophosphamideNdị na - egbochi MAO Chloramphenicol, Theophylline, Allopurinolsulfonamides ogologo oge, Fenfluramine, Pentoxifylline, Fluoxetine, Guanethidine, Ihe ndozi, ihe nzuzo nzuzo, Dipu, Bromocriptine, Pyridoxine, ethanol, yana ọgwụ ndi ozo hypoglycemic (insulin, biguanides, acarbose).

Nkwonkwo nke Glidiab na obi glycosides na-eme ka ọgwu etolite bawanye extrasystole ventricular.

Nsonaazụ nke ckers-blockers Ihe ndozi, Clonidine, Guanethidine nwere ike iwepu ihe mgbaàmà nke ọrịa hypoglycemia.

Ntụziaka pụrụ iche

Ekwesịrị ịkwado ọgwụgwọ Glidiabusoro ọgwụgwọ nri kalorina ntinye pere mpe carbohydrates.

Mbelata nri n’ime nri, yana nrụgide nke mmetụta uche na nke anụ ahụ chọrọ mmezi usoro ọgwụgwọ gliclazide.

N'oge usoro ọgwụgwọ, ọ dị mkpa iji nyochaa ọkwa glycemiana-elele ya na afọ na-adịghị na mgbe ị risịrị nri.

Na decompensation ọrịa shugaka ihe ogwugwo ekwesiri ịtụle ojiji enwere ike nwere insulin nkwadebe.

Ekwesịrị ịgwa onye ọrịa banyere ohere enwere ike imepụta ya hypoglycemia mgbe ị na-ebu ọnụ, na-ewere Ndị NSAID na ethanol nwere nkwadebe.

Nke kachasị emetụta mmetụta nke ọgwụ hypoglycemic bụ ndị ọrịa agadi, ndị ọrịa na-esighi ike, ma ọ bụ ndị na-anaghị enweta nri kwesịrị ekwesị, yana ndị mmadụ na-ata ahụhụ site na ya. hypocorticism.

Ekwesịrị ịkpachara anya mgbe ị na-arụ ọrụ dị ize ndụ ma ọ bụ na-arụ ọrụ nkenke, yana ịkwọ ụgbọ ala, ọkachasị mgbe a na-ahọpụta usoro usoro onunu ogwu, n'ihi ihe egwu dị ike nke ịmepụta hypoglycemia.

• Glemaz,
• Amaril,
• Igwe,
• Amix,
• Glibetic,
• Diabrex,
• Glianov,
• Maninil,
• Glibenclamide,
• Diameprid,
• Glimepiride,
• Diapiride,
• Glinova,
• Meglimide,
• Glurenorm,
• Ọlta,
• Eglim wdg

• Glidia MV,
• Diabeton MR,
• Pịa,
• Ntugharị,
• Gliclazide MR,
• Diagnizide MR,
• Gluktam,
• Diabinax,
• Glucostabil,
• Diatik,
• Glioral,
• Diabresid,
• Osiklid.

Ahụmahụ nke ọgwụgwọ Glidiab na ndị ọrịa na ọgbọ nke ụmụaka ezughị maka nhọpụta ụmụaka.

Mmanya na-aba n'anya

Ọ bụrụ na ị alcoholụọ mmanya mgbe ị na-a therapyụ ọgwụ Glidiab, ị nwere ike ịnwetadisulfiram-like mmeghachi omume Ọrịa mgbu afọ, ọgbụgbọ/vomiting, isi ọwụwa.

N'oge ime na lactation

Jiri na ọgwụgwọ nke Glidiab na inye ara na nke afọ ime amachibidoro.

Nyocha Glidiab achọpụtara na ụgbụ ahụ dị ole na ole, ma ọ dị mma. Dabere na ndị ọrịa na-anata ya, ọgwụ ahụ na-anagide ngosipụta na-adịghị mma zuru oke. ọrịa shuga na-abụghị insulin ma nwee obere nsonaazụ ya. Dị ka o kwesịrị ịdị, mgbe ị na-ewere Glidiab, ịkwesịrị idowe nke kwesịrị ekwesị nri ma soro ntuziaka maka mmega ahụ.

Mwepụta wepụtara ya na ihe mejupụtara

Thedị usoro iji wepụta Glidiab MV bụ mbadamba ihe nwere ndọtị edoziri: ewepụghị-cylindrical, ọcha nwere ude ma ọ bụ nke nwere agba, beveled, marbling bụ ihe a na-anabata (mpempe 10 na blisters, na ngwungwu kaadi nke 3 ma ọ bụ 6 ngwugwu).

Ngwakọta 1 mbadamba:

• ihe na-arụ ọrụ: gliclazide - 30 mg,
• ihe inyeaka: microcrystalline cellulose - 123 mg, hypromellose - 44 mg, magnesium stearate - 2 mg, colloidal silicon dioxide - 1 mg.

Mlọ ọgwụ

Gliclazide mgbe nchịkwa a na-ekwu okwu nke nta nke nta na-etinye obi gị dum na eriri afọ. Nleta plasma ya na-abawanye nwayọ nwayọ wee ruo na kacha n'ime awa isii na isii. Iri nri anaghị emetụta mmịpụta nke ihe ahụ.

Na otu uzo Glidiab MV kwa ụbọchị, a na-enye nsị plasma ọgwụgwọ gliclazide dị irè ruo awa 24.

Njikọ protein protein Plasma bụ ihe dịka 95%.

Metabolism na-eme n'ime imeju ya na usoro na-esote metabolites na-adịghị arụ ọrụ.

Ndi_1/2 (ọkara ndụ) bụ ihe dịka elekere 16. Ọ bụ ọpụrụ iche bụ akụrụ n'ụdị metabolites, ihe dịka 1% nke ihe ahụ apụtaghị na mmamịrị.

Ihe ngbanwe

• ụdị shuga 1
• ọrịa mamịrị ketoacidosis,
• mamịrị koko / precoma,
• ọnọdụ nke ịrịa ọrịa nri, ọrịa nke ịba ọcha n'anya (ọrịa na-efe efe),
• hyperosmolar coma,
• paresis nke afo
• leukopenia
• nnukwu ịba ọcha n'anya / gbasara akụrụ,
• eriri afọ,
• otutu ihe ogwugwo, oria di uku, oku oku, na onodu ndi ozo nke choro inweta insulin.
• ngwakọta ọgwụgwọ na miconazole, danazole ma ọ bụ phenylbutazone,
• afọ ruo afọ 18
• ime na lactation,
• ndị mmadụ ịleomi ihe ọ bụla mejupụtara ọgwụ ahụ, yana sulfonamides na ihe ndị ọzọ na-emepụta sulfonylurea.

Ikwu (Glidiab MV ka edepụtara n'okpuru nlekọta ahụike):

• ọrịa febrile
• a .ụrụma
• edozi, nri adịghị edozi,
• enweghi ike imu nwa
• ọrịa siri ike nke sistem obi (gụnyere atherosclerosis, akwara obi)
• gbasara akụrụ
• hypopituitarism,
• ụkọ glucose-6-phosphate dehydrogenase,
• iji glucocorticosteroids mee ogologo oge,
• ọrịa thyroid, na-aga n'ihu na imebi ọrụ ya,
• nká.

Ntụziaka maka iji Glidiab MV: usoro na usoro onunu ogwu

A na-ewere Glidiab MV ọnụ, oge 1 kwa ụbọchị n'oge nri ụtụtụ.

Ọ bụ dọkịta ga-ahọrọ ọ̀tụ̀tụ̀ ọgwụ ahụ n’otu n’otu dabere n’ihe ngosipụta nke ọrịa ahụ, glucose na-ebu ọnụ na awa 2 mgbe nri gasịrị.

Initialbọchị izizi gị bụ 1 mbadamba. N’ọdị n’ihu, ọ bụrụ na ọ dị mkpa, iwelie onyonyo ka ọ dịkarịa ala izu abụọ. Oke kachasị bụ 4 mbadamba kwa ụbọchị.

Ọ ga-ekwe omume ịgbanwe site na Glidiab gaa Glidiab MV na mbadamba 1-2 kwa ụbọchị.

Enwere ike ijikọ ọgwụgwọ ahụ na ndị nnọchianya hypoglycemic ndị ọzọ: biguanides, insulin ma ọ bụ inhibitors alpha-glucosidase.

Mkparịta ụka ọgwụ ọjọọ

Njikọ nke glukos ọbara nwere ike ịbawanye (na-ebelata ike nke gliclazide):

• Danazole: a akwadoghi ngwakọta a, ọgwụ ahụ nwere ọria mamịrị, ọ bụrụ na ọ gaghị ekwe omume iji ọgwụ ọzọ dochie ya, a ga-enyocha nsonaazụ glucose dị n'ọbara, enwere ike idozi ọnya Glidiab MV n'oge ọgwụgwọ ejikọtara yana mgbe dọkịta gụchara ya,
• chlorpromazine (na ọgwụ kwa ụbọchị nke 100 mg): nchikota ahụ chọrọ ịkpachara anya, ebe enwere mmụba nke glucose ọbara yana mbelata insulin, ma ọ bụrụ na ọ gaghị ekwe omume iji dochie ya na ọgwụ ọzọ, a ga-enyocha ọkwa glucose ọbara, n'oge ọgwụgwọ ngwakọta na mgbe ọ gwụchara. doziri uzo Glidiab MV,
• tetracosactide na glucocorticosteroids (ojiji mpaghara / sistemu: intraarticular, rectal na mpụga nchịkwa): njikọta ahụ chọrọ ịkpachara anya, ebe ọ bụ na enwere mmụba nke mkpịsị ọbara ọbara na mmepe nke ketoacidosis, a na-atụ aro ka iji nlezianya na-elebara mkpokọ glucose ọbara, karịsịa na mmalite ọgwụgwọ, n'oge mgbakwunye ọgwụgwọ, n'oge agbakọta. Usoro ọgwụgwọ na mgbe ọchara dọkịta gachara, enwere ike ịhazigharị ọgwụ Glidiab MV,
• salbutamol, ritodrin, terbutaline (nchịkwa intravenous): nchikota a choro ịkpachara anya,
• anticoagulants (ọkachasị warfarin): ịba ụba nke anticoagulants (enwere ike ịhazigharị dose).

Njikọ ọnụ nke ihe egwu nke ịbawanye hypoglycemia na-abawanye (mmụba nke gliclazide):

• miconazole (sistem ma ọ bụ ngwa mpaghara n'ụdị nke jeliki na akpụkpọ ahụ mucous nke oghere ọnya): a na - egbochi ngwakọta ahụ, ebe ọ bụ na hypoglycemia nwere ike itolite ruo mgbe akpịrị na-ama.
• phenylbutazone (usoro nchịkwa): a naghị akwado ngwakọta ahụ, ọ bụrụ na ọ gaghị ekwe omume iji ọgwụ ọzọ dochie ya, ị ga-enyocha nsonaazụ glucose dị n'ọbara, dọkịta Glidiab MV nwere ike idozi ya n'oge ọgwụgwọ ngwakọta na mgbe ọ gwụchara,
• ethanol: anaghị atụ aro ihe nchikota, nke ejikọtara ya na hypoglycemia mụbara yana ohere nke ịmalite hypoglycemic coma,
• ndị ọzọ hypoglycemic (insulin, alpha-glucosidase inhibitors, metformin, thiazolidinediones, dipeptidyl peptidase-4 inhibitors, glucagon-peptide-1 agonists), ọgwụ mgbochi na-abụghị steroidal, fluconazole, beta-adrenergic mgbochi ndị na-egbochi, neurotrans₂- ndị na-anabata ya, nke a na-akpọ monoamine oxidase inhibitors, clarithromycin, sulfonamides: njikọta chọrọ ịkpachara anya.

Ihe analogues nke Glidiab MV bụ: Diabeton MB, Diabefarm MV, Gliclazide Canon, Glidiab, Gliclada, Diabetalong, Diabinax, Diabefarm.

Omume General

A na-ahụta ọgwụ "Glidiab MV 30" ka analogue nke ọgwụ French "Diabeton MV". Ọ bụ Akrikhin Chemical na ọgwụ na mpaghara Moscow mepụtara ya.

Ọgwụ a na-ezo aka na ọnya ọgwụ hypoglycemic dị n'ụdị mbadamba nwere mgbapụta gbanwetụrụ. Colorcha nke ihe owuwu ha bụ ọcha ma ọ bụ ude, nwere ike ịbụ ihe mabul. Mbadamba yiri oche ndị dị larịị.

Nkwakọ ngwaahịa bụ ngwugwu. O nwere ike inwe mbadamba 30 ma ọ bụ 60, nke a na-etinye ya na efere.

N'adịghị ka ọgwụ “Diabeton MV” nke nwere 0.060 g nke gliclazide, ọgwụ “Glidiab MV” nwere nnukwu ihe ọrụ na-arụ ọrụ oge abụọ dị ala, nke bụ 0.030 g.

Ihe ndị dị na tebụl na-adịghị arụ ọrụ gụnyere hydroxypropylmethyl cellulose, ụmụ irighiri mmiri aerosilic, magnesium stearate, microcrystalline cellulose.

Onwe ogwu ahu bu "Glidiab" na ngwusi ndi ozo. Usoro onunu ogwu n’otu mbadamba bụ 0.08 g nke gliclazide.

Olee otu o si arụ ọrụ

Ntụziaka maka itinye aka na ọgwụ Glidiab MV na-akọwa nsonaazụ nke glyclazide, nke na-akpali insulin na-emetụta ihe n’ime β-sel dị na akwara.

N'okpuru mbadamba mbadamba, ihe insulin na-arụ ọrụ nke ụmụ irighiri glucose na-abawanye, anụ ahụ na -akpata na-eme ka ọ na-eme ka mmiri ọgwụ insulin dịkwuo nkọ.

Muscle glycogen synthetase, ịbụ enzyme intracellular, dị irè karị. Enwere ntakịrị na etiti ahụ site na mmalite nri ruo na ntọhapụ nke homonụ. A na - eweghachi insulin insulin n'oge mbido mbụ, nke na - achọpụta gliclazide site na ndị ọzọ na - eme ntụpọ, na - eme nke na - eme na agba nke abụọ. Ọkwa glucose postprandial na-ebelata.

Enwere oganihu na microcirculation n'ihi nnwekọ na nrapado nke sel platelet, nhazi nke permeability nke vaskụla mgbidi, mbelata mmepe nke microthrombotic na atherosclerosis Filiks, na iweghachi mmeghachi omume nke mgbasa nke mkpụkọ ọbara. Ohere nke mmeghachi nke ihe nnabata n'ụkpụrụ ọbara n'ahụ ụmụ irighiri ihe adrenaline na-ebelata.

Ọgwụ na-enwe ike belata ụdị ọrịa mamịrị nke ọrịa retinopathy na ọkwa na - abụghị protinerative. Ogologo oge ị withụ ọgwụ a na ọnọdụ nke ọrịa mamịrị mebiri akụkụ nke akụrụngwa akwara nwere mmụba nwere ike belata mmịpụta nke protein na mmamịrị.

Ọgwụ a anaghị eme ka ahụ mmadụ dị elu, kama nke ahụ, ọ na -ebelata ya n'ihi nsonaazụ nke mmalite insulin insulin. Ọ dịghị akpalite ịba ụba ọrịa.

Gịnị ka e ji eme ya?

Ndị dọkịta na-atụ aro iji ọgwụ nwere shuga dị elu nke ogo nke abụọ. A na-eme ọgwụgwọ maka ezughị ezu nke nri na mgbalị anụ ahụ.

Maka ọgwụ Glidiab MV, ihe ndị na-egosi ihe ndị ahụ metụtara mgbochi nke ịda ọrịa na ọrịa mamịrị, nke nephropathy, retinopathy, infarction myocardial na ọrịa strok mara.

Otu esi eji ya

A họrọ usoro ị Theụ ọgwụ ahụ maka onye ọrịa ọ bụla iche, na-eburu n'uche ngosipụta nke ọrịa ahụ, ịta ahụhụ glucose na afọ na-enweghị isi na nkeji iri abụọ mgbe iri nri gasịrị.

Maka ọgwụ "Glidiab MV", ntuziaka maka iji kọwaa ọgwụ mbido nke 0.03 g kwa ụbọchị, nke ya na otu mbadamba. Ekwuputara nlebara anya a maka ndị ọrịa agadi ka afọ 65 gbachara. A na-eji ọgwụ eme ihe n ’otu mbadamba ụtụtụ mgbe nri ụtụtụ.

Ọ bụrụ na ọ dị mkpa, a na-amụba usoro onunu ogwu kwa izu abụọ. Anabataghị otu ụbọchị ka ọ dị ihe dị ka 0.120 g, nke dabara na mbadamba 4.

A na-eji ọgwụ "Glidiab MV" eme ihe kama iji ọgwụ nke otu aha ahụ na mwepụta ndị a na-emebu, na-eri mbadamba 1-4 kwa ụbọchị.

Ejikọtara ya na ihe nnọchianya hypoglycemic nke dabeere na biguanide, ihe mgbochi alpha-glucosidase na-egbochi irighiri insulin.

Ọ bụrụ na arụ ọrụ ezumike ezumike nke ọdịdị adịghị ike ma ọ bụ agafeghị oke, mgbe mgbakwunye mkpụrụ ọkụ creatinine abụghị ihe karịrị 0.080 L kwa nkeji, a naghị ebelata usoro onunu ogwu ahụ.

Mgbe agaghị

Agaghị akwado mbadamba Glidiab MV maka ojiji n'ụdị mbụ nke ọrịa shuga mellitus, na mmụba nke ketones na mmamịrị, ya na gastric paresis, nwere hyperosmolar, ọrịa shuga na precoma, nwere nnukwu ịwa ahụ na ọkụ mmerụ ahụ, usoro traumatic mgbe achọrọ insulin. ọgwụgwọ.

Contraindications bụ mmebi siri ike nke ọrịa ịba ọcha n'anya ma ọ bụ akụrụ, mgbochi afọ, mgbanwe na nri nri, mmepe nke steeti hypoglycemic.

Nweghị ike iji ọgwụ ahụ maka ahụ ọkụ, leukopenia, ịtụrụ ime, na-enye nwa ara na ị intoụbiga mmanya ókè.

Ọ dị mkpa ịkpachara anya mgbe ị na-a theụ ọgwụ, nlekọta pụrụ iche na nhọrọ ọnụọgụ maka ndị ọrịa ị dependụ mmanya na nsogbu nke gland thyroid.

Njirimara ọgwụgwọ

Maka ọgwụ "Glidiab MV", ntuziaka maka iji gosipụta mkpa ọ dị ijikọ ya na obere kalori, gụnyere ọdịnaya carbohydrate dị ala. Nyochaa nlebara anya nke ịba ụba nke glucose na n'ọbara ụtụtụ site na ụtụtụ tupu mgbe oriri gachara.

Y’oburu na enwere ogwugwo ma obu ekpughere onodu oria n’azu, iwebata insulin puru omume.

Enwere ịdọ aka ná ntị banyere ihe omume hypoglycemic na-aba n'anya na ị useụ mmanya ethyl, ihe na-abụghị ọgwụ steroidal mgbochi mkpali na enweghị nri. Alcohol Dụ mmanya na-egbu egbu nwere ike ime ka ọrịa disulfiram dịka ọrịa, ebe isi na afọ na-afụ ụfụ, ọgbụgbọ na ọgbụgbọ ga-ekwe omume.

Ekwesịrị idozi usoro ịụ ọgwụ ahụ n'oge nrụgide anụ ahụ ma ọ bụ nke mmetụta uche yana ị foodụ nri na-adịghị ahụkebe.
Ọ kachasị emetụta mmetụta nke ọgwụ ahụ bụ ndị agadi, ndị ọrịa nwere nsogbu na-edozi ahụ ma ọ bụ nke na-adịghị mma, ndị ọrịa na-arịa ọrịa na-enweghị ike nke usoro adrenal-pituitary.

Na usoro mmalite nke iji ọgwụ ahụ mgbe ị na-ahọrọ usoro onunu ogwu, ọ bụrụ na enwere nsogbu ga - akpata nsogbu hypoglycemic, ịkwesighi ịme ihe omume chọrọ nlebara anya na mmeghachi omume psychomotor ngwa ngwa.

Mmeghachi omume ọjọọ

Maka Glidiab MV, nkuzi ahụ gụnyere ozi banyere ihe ndị na - adịghị ahụ anya na akụkụ endocrine n'oge arụ ọrụ nke njikwa mbadamba na n'oge nri na-adịghị mma. Dị ka ọ na-adịkarị, mbelata glucose n’arụ ọbara na-eme ka ọ bụrụ isi ọwụwa, ike gwụ, agụụ, enweghị enyemaka, ọdịmma ụjọ, adịghị ike ngwa ngwa, iwe iwe, itinye uche na-adịghị ike, na ọnọdụ ịda mba. Ọzọkwa, enwere mgbanwe na nhụhụhụhụhụhụhụhụhụju, oke ụjọ, nhụjuanya na nsogbu nke ọgbụgba, ọgbụgbọ, hypersomnia, iku ume, yana mbelata obi.

Akụkụ nri digestive malfunction n'ụdị malabsorption, ọgbụgbọ, afọ ọsịsa, enweghị nri agụụ, ọrụ imeju na-egbu, cholestatic jaundice, ịba ụba enzymes transaminase.

Usoro ndị a na-achọghị na sistemu na hematopoietic metụtara mbelata hemoglobin, platelet na leukocyte.

Ọgwụ nwere ike ịme ka ekpughe ihe nfụkasị n'ụdị itching, urticaria, flop maculopapular.

Okwu mmeghe

Ntụziaka maka ojiji agbakwunyere na Glidiab MV remedy adọ aka ná ntị megide ịdoụbiga mmanya ókè, nke gosipụtara site na mbelata mgbanye glucose na plasma ọbara. Site na oke ọgwụ siri ike, mmepe nke mmiri ọgwụ hypoglycemic ga-ekwe omume.

Iji wepu ya, a na-enye mmadụ ohere iri nri hydrocarbons nke ọma, dịka ọmụmaatụ, otu shuga. Mgbe mmadu n’amaghi ama, a na - etinye mmiri dextrose 40% ma ọ bụ glucose n’ime akwara, a na-etinyekwa glucagon n’ime akwara n’otu 1 mg. Ọ bụrụ na onye ọrịa ahụ teta, mgbe ahụ ọ ga-amanye iri hydrocarbons nke ọma iji zere ịwakpo hypoglycemic ọgụ.

Njikọ ya na ọgwụ

The hypoglycemic ọrụ nke agwọ ọrịa "Glidiab CF 30 mg" nwere ike enwekwukwa ewebata yiri angiotensin n'ịtụgharị enzyme inhibitor na Monoamine oxidase ụdị ihe nnabata blocker formations beta adrenozavisimyh na H2 gistaminozavisimyh dabeere cimetidine, na flukonazolovyh mikonazolovyh antifungal ọgwụ ọjọọ, ndị na-abụghị steroidal mgbochi mkpali mmadụ phenylbutazone, indomethacin, diclofenac.

A na - eme ka mmetụta nke mbadamba ndị ahụ pụta na clofibrates na bezafibrates, ọgwụ mgbochi TB site na otu nke ethionamide, salicylates, anticoagulant comprect computera coumarin, steroid anabolic, cyclophosphamides, chloramphenicol, sulfonamides nwere mmetụta na-adịte aka.

Ọgwụ a na-eme ka ọ dịkwuo mma, ọ na -ebelata shuga ọbara n'oge iji tubular blockers, ethyl mmanya, acarbose, biguanide, insulin.

Mbelata mmetụta hypoglycemic nke mbadamba bụ ihe kpatara barbiturates, ọgwụ ndị dabere na epinephrine, clonidine, terbutaline, rhytodrin, salbutamol, nwekwara phenytoin, ndị na-egbochi carbon enzyme carbon dị ka acetazolamide, thiazide diuretics, homonụ nke thyroid gia nwere

Molecules nke ethyl mmanya na-enwe ike ịme ihe na gliclazide na ntinye nke usoro disulfiram.

Akụkụ ndị dị n'ọrụ nke mbadamba nkume ndị ahụ na-akpata depolarization na mbufụt nke ventricles nke akwara myocardial mgbe ejikọtara ya na glycosides cardiac.

Beta-blockers, clonidine, reserpine, ọgwụ guanethidine na-ekpuchi hypoglycemia clinical.

Echiche onye ọrịa

Ihe dị mkpa abụghị naanị ntuziaka maka ojiji ejiri ọgwụ Glidiab MV. Nyocha na-ekwu banyere ihe ndị ọrịa na-eche banyere ịdị irè nke ọgwụ. Ngwá ọrụ a na-enyere ọtụtụ ndị ọrịa aka belata mkpokọta glucose na ụkpụrụ nkịtị, yana ijikọ ya na nri na-agbanwe ụzọ ndụ onye ọrịa.

Ndị mmadụ mara na akụkụ dị mma nke mbadamba ahụ bụ ojiji ha dabara n'ụtụtụ. N'ehihie, ịnweghị ike icheta mkpa ọgwụgwọ.

Na ọgwụ "Glidiab MV" nyocha nwere ike ịnụ yana adịghị mma na ọdịdị, jikọtara na arụmọrụ arụ ọrụ a. Nke a na - abụkarị mgbe usoro ọgwụgwọ ezughị oke, mgbe edepụtara ọgwụ ole na ole.

Ngwakọta na ịhapụ ụdị

• Ọrụ: 0.03 g nke gliclazide
• Ihe inyeaka: hypromellose, MCC, aerosil, E572.

Erere n'ụdị cylinder dị larịị nwere beveled onu, ọcha ma ọ bụ creamy. Ihe nwere ike ime ma e nwee ụlọ ahụ abụghị ntụpọ. Wokwara na 10 iberibe na blisters. Na nchịkọta kaadiboodu - 3 ma ọ bụ 6 efere efere, akwụkwọ ntuziaka onye ọrụ.

Ngwongwo na-agwọ ọrịa

Ọgwụ nke nwere mmetụta hypoglycemic nke dabeere na glycazide, usoro sitere na usoro nke abụọ nke sulfonylurea. Ọ na - akpali mmepụta nke insulin n'ime ahụ, na - eme ka anụ ahụ nwee mmetụta nke insulin na mmetụta nke glucose. Na-eweghachi ọnụ ọgụgụ insulin nkịtị, na-eme ka microcirculation dịkwuo ala, belata nchịkọta platelet, na-eweghachi ike akwara dị mkpa.

Theakingụ ọgwụ adịghị enye aka na nchịkọta nke paụnd ọzọ, ebe ọ bụ na ọ kacha emetụta mmalite nke oke oghere insulin.

Ofzọ nke ngwa

Ezubere ọgwụ a naanị maka ọgwụgwọ okenye. Mpempe akwụkwọ Glidiab MV, dị ka ntuziaka maka iji ya si dị, a na-ewere ya otu ugboro n'ụbọchị, kachasị mma n'ụtụtụ na nri. Erere ọgwụ ndị ahụ, ha agaghị ata ya ahụhụ ma ọ bụ gwepịa ya.

Ọ bụrụ na n'ihi ihe ụfọdụ, anabataghị nnabata gị, mgbe ahụ, ị ​​na-atụ aro ka ịhapụ ịkọwa ihe omimi ahụ ugboro abụọ. Erere a na-echefu eche kwesịrị ị drunkụ mmanya echi ya. Usoro ọgwụgwọ nke ọgwụ ahụ, dị ka ọgwụ hypoglycemic ọ bụla, a na-ahọrọ onye ọ bụla maka onye ọrịa ọ bụla dabere na akaebe ya nke glucose ọbara na ọkwa hemoglobin.

Usoro ọgwụgwọ akwadoro akwadoro bụ 30 mg kwa ụbọchị. Mgbe e mesịrị, enwere ike idozi ya na 60, 90 na 120 mg. Ọ na-ekwe ka iwelie ọgwụ kwa ụbọchị ka ọgwụ ọjọọ naanị otu ọnwa mgbe nke mbụ. Ihe dị iche bụ ikpe mgbe ọgwụgwọ izizi enyeghị nsonaazụ ahụ a tụrụ anya ya, ọkwa glucose wee nọgide na otu ọkwa (tupu usoro ọgwụgwọ). N'ọnọdụ a, usoro ọgwụgwọ ahụ nwere ike ịbawanye na mbụ - ka ụbọchị 14 gachara.

HF nwere ọgwụgwọ mmezi bụ 30-120 mg.

Ọ bụrụ na ọ dị mkpa ịnyefe onye ọrịa na Glidiab 80 mg na mkpụrụ ọgwụ na ogologo oge (MV 30 mg), a na-eme ya mgbe ịlele ọkwa glucose na oke nke 1: 1. Ọ bụrụ na onye ọrịa ahụ butere ọgwụ hypoglycemic ndị ọzọ na mbụ, mgbe ahụ aga-eme nnyefe ahụ na mgbako nke HF ọgwụ gara aga na oge iwepụ ya. Enweghị mkpa idebe oge mgbanwe, SN mbụ nke Glidiab MV bụ 30 mg, mgbe nke ahụ gasịrị enwere ike ịgbanwe ya.

Ọ bụrụ na onye ọrịa ahụ were ọgwụ were ogologo oge nke ihe na-arụ ọrụ, ọ ga-emerịrị iji gbochie ihe mmetụ ahụ. Mgbe nke a gasịrị, ị nwere ike ịmalite ị drugụ ọgwụ ogologo oge yana ịsụ ọgwụ 30 kwa ụbọchị.

Adjustmeghari usoro ọgwụgwọ oge afọ maka ndị ọrịa agadi (65+) achoghi ya. Maka ndị nọ n'ihe ize ndụ, a na-atụkwa 30 mg nke CH.

Na mgbochi nke ọrịa shuga, enwere ike ịbawanye usoro onunu ogwu kwa ụbọchị ka uru kachasị nke 120 mg dịka ihe mgbakwunye nri na mmega ahụ. A na-eme ntughari ruo mgbe ihe ndị ahụ na-ahazi, na-eburu n'uche ihe ize ndụ nke hypoglycemia.

N’ime ime, HB

Ọ bụ ihe a na-achọghị ka ụmụ nwanyị jiri ọgwụ ọnụ na-eme ka glucose ọbara dị ala n'oge ịmụ nwa, ebe ọ nweghị ihe akaebe na nchekwa nke Glidiab MV.

Na nkwadebe maka ịtụrụ ime ma ọ bụ mgbe ọ mere na mbido usoro mbadamba Glidiab MV, a ga-akagbu ọgwụ ahụ ma kọọkwa nke nwanyị.

Enweghị data a pụrụ ịdabere na ya banyere ma ihe ahụ na-arụ ọrụ na-abanye na mmiri ara ara; ya mere, ọ bụ ihe na-achọghị oke mma ijikọta ọgwụ hypoglycemic na lactation. N'oge ị na-ewere mbadamba HB, ekwesịrị ịkagbu ya ka ọ ghara ịkpalite mbelata ọbara glucose na nwata.

Mkparịta ụka ọgwụ ọjọọ

Mgbe ị na-eji mbadamba nkume Glidiab MV, ikike nke gliclazide meghachi omume na ọgwụ nke ọgwụ ndị ọzọ kwesịrị iburu n'uche.Karịsịa dị ize ndụ nwere ike ịbụ ngwakọta na ọgwụ ndị na-akwalite nsonaazụ nke gliclazide, ebe ọ bụ na a na-atụwanye egwu nke hypoglycemic coma.

A machibidoro iwu ijikọ ọgwụgwọ Glidiab MV na Miconazole (sistemu ma ọ bụ na mpụga n'ụdị jel), n'ihi na nke a na-enye aka n'ụdị dị njọ nke coma, nke nwere ike ibute ọnwụ.

Achọghị ijikọ ọgwụ ahụ na phenylbutazone maka otu ihe ahụ. Ekwesịrị iji ọgwụ mgbochi mkpali ọzọ dochie ya. Ọ bụrụ na ọ gaghị ekwe omume ịkagbu ya, onye ọrịa ahụ kwesịrị ịma ihe ọghọm dị na ya na mkpa ọ dị ịchekwa glucose n'ọbara.

A machibidoro ị combineụ mmanya na ọgwụ mmanya ethanol nwere, ebe ọ bụ na mmanya na-akwalite mmepe nke hypoglycemic coma.

Enwere ọtụtụ ọgwụ ị nwere ike ịchebara ya nke ọma yana Glidiab MV. Drugsdị ọgwụ ndị a gụnyere insulin, metformin, alfa-glucoside inhibitors, beta-blockers, sulfonamides, NSAIDs, wdg Ọ bụrụ na ọ dị mkpa, a ga-enyocharịrị ojiji ha maka mgbaàmà ndị achọghị.

Danazol na-arụpụta ọrịa mamịrị, na-ebelata mmetụta nke gliklidiza ma na-enyere aka iwelie nchịkọta nke glucose n'ọbara. Ọ bụrụ na ọ gaghị ekwe omume iji ọgwụ ọzọ dochie ọgwụ ahụ, onye ọrịa ahụ kwesịrị ịdị na-enyocha ọkwa shuga mgbe niile, ọ bụrụ na ọ dị mkpa, ekwesịrị ịhazigharị usoro nke Glidiab MV.

Chlorpromazine na-abawanye glucose ọbara ma na-ebelata usoro insulin. Ọ dị mkpa ịchịkwa shuga na ndị ọrịa mamịrị, iji nlezianya kpebie etu esi a gụ ọgwụ gliclazide ya na ojiji Glidiab MV mgbe ejiri Chlorpromazine gwọọ ya.

Ọgwụ nke corticosteroids nwere usoro ntinye ọ bụla (mpụga, mpaghara, intravenous ma ọ bụ rectal) na-abawanye itinye glucose ma na-atụnye ụtụ na ketoacidosis. Mgbe ejikọtara ya na ụdị ọgwụ a, a na-enyocha shuga n'ọbara mgbe niile ọ dị mkpa iji nlezianya chọpụta usoro ọgwụgwọ kachasị dị nchebe ma n'otu oge ahụ na mgbe njedebe nke ọgwụgwọ homonụ gasịrị.

N'iji usoro nkwonkwo na anticoagulants, ọ ga-ekwe omume ịkwalite ọrụ ha. Dose ukpụhọde chọrọ.

Nsonaazụ

Iwere mbadamba Glidiab MV nwere ike inwe mmeghachi omume anụ ahụ na-achọghị.

Dịka ọgwụ niile nke otu ụdị sulfonylurea, ọgwụ nwere ike ịkpalite hypoglycemia ma ọ bụrụ na ewere mbadamba ndị ahụ n'oge adịghị mgbe ụfọdụ na-ejikarị nri agbari. N'ụdị ndị a, ọnọdụ a ga - eso:

• Isi ọwụwa
• Agụụ na-agụsi ike
• Nausea, mkpọtụ nke ọgbụgbọ
• Ike ike
• Inwe agujuu ma obu ura
• Mgbakasị ahụ siri ike
• Obi uto
• Inhibido mmeghachi omume
• Ihe ndọpụ uche
• Obi erughị ala
• Ihe ọghọm nke mmụọ, okwu na ọhụụ
• Dizziness
• Mmepo
• Igwe iku ume
• Delirium
• N'ọnọdụ ndị dị oke njọ, enweghị mmụọ ma ọ bụ ọnwụ nwụrụ.

Ọzọkwa, onye ọrịa ahụ nwere ike ịnweta mmeghachi omume ndị ọzọ:

• Ọsụsọ mụbara
• Isi akpụkpọ
• Otito nke BP
• Tachycardia
• Arrhythmia
• Angina pectoris.

N'aka nke ọzọ, iburu mbadamba ihe nwere ike ibute ọrịa dị iche iche nke akụkụ ụfọdụ:

• Afọ afọ: ọgbụgbọ, mkpọchi ọgbụgbọ, mgbu afọ, afọ ọsịsa ma ọ bụ afọ ntachi. Iji zere ọnọdụ ndị achọghị ma ọ bụ belata ike ha, a na-atụ aro mbadamba ihe oriri.
• Akpukpo aru: rashes, itching, edere Quincke, erythema, mmeghachi omume ojoo.
• Akụkụ Hematopoietic: anaemia, leukopenia, thrombocytopenia. Ọnọdụ ahụ bụ nwa oge: ha na-ebufe onwe ha mgbe akagbuo ọgwụ.
• Imeju: mmeju nke enzymes, na obere - ọrịa ịba ọcha n'anya. Ọ bụrụ na enwere akara nke cholestatic jaundice, mgbe ahụ, ekwesịrị ịkagbu usoro ọgwụgwọ.
• Organs nke ọhụụ: ibelata na anya acuity (ọ na - abụkarị na mbido usoro n'ihi mgbanwe glucose).

Mmetụta ndị ọzọ na-egosipụta njirimara nke nkwadebe sulfonylurea gụnyere:

• Erythropenia
• Ọbara
• Ọrịa vasculitis
• Hyponatremia
• Agranulocytosis.

Usoro na ọnọdụ nchekwa

Glidiab bụ ọgwụ ọgwụ.

Debe mbadamba ihe n’ebe kpọrọ nkụ, anaghị enweta ya iji mmiri na anwụ, mgbe ọ bụla okpomoku ruru 25 ºС. N'okpuru ọnọdụ ndị a, ndụ nchekwa nke Glidiab bụ afọ 4, Glidiab MV bụ afọ 2.

Hụrụ njehie na ederede? Họrọ ya wee pịa Ctrl + Tinye.

Principlekpụrụ nke ọgwụ

Ọgwụ maka ịgwọ ọrịa "ụtọ" nke ụdị nke abụọ dị na ụdị mbadamba, isi ihe na-arụ ọrụ nke ọgwụ ahụ bụ glyclazide. Ngwakọta nke mbadamba ndị ahụ gụnyere ihe ndị ọzọ - microcrystalline cellulose, magnesium stearate na ihe ndị ọzọ.

Nkpirisi okwu “MV”, dị n’aha ọgwụ, na-anọchite ntọhapụ gbanwere. Nyocha nyocha nke ndị dọkịta na-ekwu na nsogbu a na-enye gị ohere ị theụ ọgwụ otu ugboro n'ụbọchị.

Isi ihe n'oge a na-eme ka mmiri na-enyere aka na-akpali ọrụ nke glycogen synthetase na imepụta insulin hormone na ahụ. Na mgbakwunye, isi ihe na-ekpebi ihe insulin na-eme na nzuzo shuga, na-ebute mmetụ ya na ọkwa sel.

Ezigbo ihe dị mkpa bụ eziokwu na mbadamba Glidiab na-enyere aka belata oge n'etiti ihe oriri na mmalite nke insulin na-arụ ọrụ. Nkọwa banyere ọgwụgwọ a na-egosi na iji ọgwụ ahụ eme ihe na-ebelata ọnụ ọgụgụ hyperglycemic dị elu, ebe enwere mweghachi nke mbido homonụ mbụ.

Ihe ndị a niile dị n’elu nwere mmetụta ha na metabolism na microcirculation. Ojiji nke Glidiab nke ọgwụ na-ebelata ohere nke ịmalite mgbanwe atherosclerotic na akwara ọbara.

N'ihi ogo nke usoro onunu ogwu, otu uzo kwa ubochi na - ekwe nkwa ịgwọta ọgwụgwọ dị mma nke ihe na - arụ ọrụ na plasma maka awa 24.

Ntuziaka maka mbadamba mbadamba

Ogwu a na-akpọ Glidiab MB na-egosi na a na-atụ aro ọgwụ ahụ maka ịgwọ ọrịa shuga mellitus yana nri nwere obere carb na mmega ahụ zuru oke.

Dịka iwu, ọgwụ mgbe niile na-arụ ọrụ dịka naanị ụzọ iji belata shuga ọbara. Naanị n'ọnọdụ pụrụ iche ka enwere ike ịkwado ya na usoro ọgwụgwọ dị omimi nke ọrịa ahụ. Dịka ọmụmaatụ, yana mgbakwunye na nkwadebe sitere na ìgwè biguanide.

Ejiri usoro onunu ogwu a dabere na egosi shuga n’ime afọ efu, yana elekere abụọ ka nri.

Na Glidiab, ntụziaka maka iji nye ozi ndị a:

1. A na-atụ aro ka ewere ya mbadamba otu ugboro n'ụbọchị, oge kachasị mma bụ ụtụtụ tupu eri.
2. Na nkezi, usoro onunu ogwu kwa ubochi bu 80 mg, nke gunyere ndi agadi oria (kariri 65).
3. Ọ bụrụ na ọgwụgwọ ahụ ezughi oke, ọ nwere ike iji nwayọ jiri nwayọ dịkwuo ogologo oge site na nkeji iri na anọ.
4. Usoro kachasị a maximumụ kwa ụbọchị adịghị ihe karịrị 320 mg.

Ọ bụrụ na onye ọrịa ahụ nwere nsogbu imeju na akụrụ, yabụ idozigharị ọgwụ nke Glidiab MV.

Ọnụahịa ọgwụ, ebe olu nke ihe ahụ bụ 80 mg (mbadamba 60 kwa mkpọ) bụ 134 rubles. Ọnụahịa nke mbadamba 60 n'ime usoro nke 30 mg bụ 130 rubles. Glidiab MB dịtụ ọnụ karịa, ọnụahịa ya bụ maka 60 PC. 80 mg nke ọ bụla bụ 185 rubles.

Analogues nke ọgwụ

N'ọtụtụ ọnọdụ, Glidiab adịghị mma ịkọwa n'ihi ọnụnọ nke contraindications, ohere dị elu nke nsogbu site na sistemụ akwara na usoro akwara.

N'okwu a, a na-atụ aro ọgwụ ndị yiri ya. Ihe analogues maka Glidiab bu: Mpempe, Amaryl, Diabrex, Maninil, Glurenorm na ọgwụ ndị ọzọ maka ịgwọ ọrịa shuga.

Iji dochie ọgwụ ahụ na otu ọgwụ ma ọ bụ ọgwụ ọzọ ga-ebu naanị sọks nke bịara, ọ bụghị ihe ọzọ.

Ka anyị leba anya na analogues n'uju.

• Formmetin bụ ọgwụ akwadoro maka ịgwọ ụdị ọrịa shuga 2 mgbe ọgwụgwọ nri abaghị uru ọ bụla. A na-atụkarị aro ya na ọgwụ ndị bụ usoro sulfonylurea.
• Mbadamba Maninil nwere ihe ndị bụ isi na-arụ ọrụ glibenclamide, bụ ihe dị n'ụkpụrụ sulfonylurea. Ọgwụ na-akwalite ọrụ insulin na-arụ ọrụ, na-enye utịp insulin na-asọpụrụ glucose.
• Edere Glibenclamide maka ụdị shuga nke abụọ, mgbe ọ na-agaghị ekwe omume ịkwụ ụgwọ maka ọrịa ahụ site na nri na egwuregwu. A na-enye usoro onunu ogwu ahụ dabere na ndị na - egosi shuga, ọ nwere ike ịdị iche site na 2.5 ruo 15 mg. Otutu iji ya otutu oge kwa ubochi.
• Amaryl - onye na - ahụ maka hypoglycemic, ka edepụtara maka ọgwụgwọ nke ụdị oria nke abụọ ka ọ bụrụ naanị ọgwụ ma ọ bụ jikọtara ya na insulin ma ọ bụ metformin. Dịka iwu, ị na-eji ọgwụ a eme ya ogologo oge.

Ọgwụ Glidiab na analorọ ya bara uru nke ukwuu n'ịgwọ ọrịa "ụtọ". Agbanyeghị, yana ezigbo akụ, ha nwere contraindications na mmetụta dị iche iche. Ya mere, nhọpụta ahụ kwesịrị ime naanị dọkịta.

Illsnweta ọgwụ na-enyere ahụ aka belata ọkwa glucose ma mee ka ahụ kwụsie ike n'ọkwa achọrọ. Mana, iji bulie ịdị irè nke iji ọgwụ eme ihe, onye ọrịa ahụ aghaghị ịgbaso nri na mmega ahụ iji mee ka mmetụta nke anụ ahụ dị nro gaa glucose.

Kedu ihe ị chere maka nke a? Kedu ọgwụ gị ka dọkịta gị depụtara, oleekwa ihe ị nwere ike ịkọ banyere ya site n'echiche nke ahụmịhe gị?