Erere Lozap Plus (12

Ọgwụ "Lozap" (Lozap) dị na mbadamba mkpuchi, na usoro dị iche iche site na 12.5 mn (Nke 90) ruo 50 mg (Nke 50, Nke 30). Ọzọkwa, ọgwụ "Lozap gbakwunyere" bụkwa nke otu a. Ọ dị iche na "Lozap" na nhazi. Yabụ na "Lozap" enwere naanị otu ihe na - arụ ọrụ - potassium losartan, yana “Lozap gbakwunyere” - abụọ: losartan potassium na hydrochlorothiazide. Dika ihe ndi ozo, mannitol, microcrystalline cellulose, croscarmellose sodium, magnesium stearate, povidone, macrogol, dimethicone, hypromellose, talc, odo iji mee ihe na nkwadebe.

Omume ọgwụ

"Lozap" "bụ ihe na - egbochi ọgwụ mgbochi nke na - egbochi ndị nnabata nke AT1 na - egbochi ya ma mekwaa nnabata nke ndị na - anabata angiotensin 2 na AT1 .. Ọgwụ a anaghị emetụta usoro kinin, anaghị enye aka na nchịkọta bradykinin. Lozap bụ prodrug. Metabolite ya na-arụ ọrụ (carbonxylic acid), nke edobere na usoro nke biotransformation, nwere mmetụta antihypertensive. Mgbe ejiri ọnụ gwọọ ya otu awa, "Lozap" rute n'ọbara kachasị na plasma ọbara; metabolite ya na-agbadata oke ya n'ime awa 3-4. Ọgwụ ahụ na-apụ n'anya n'ime awa itoolu. N'ime awa abụọ mbụ, losartan na-apụ apụ, yana metabolite na-arụ ọrụ - maka awa 9. Dika achoputara n'oge nyocha ogwu sayensi, a na-enweta ihe mmeriri ogwu ngwa ngwa na ngwakọta nke losartan na hydrochlorothiazide. Yabụ, ọgwụ ejikọtara ọnụ "Lozap gbakwunyere" na-anabatacha nke ọma na nsogbu ahụ.

Otu uzo Lozap nwere ihe ogwugwu ga-adi awa 6, emesia nsonaazụ ya ga-eji nwayọ belata oge otu ụbọchị. Ya mere, ịkwesịrị iji "Lozap" mgbe niile. Site na nchịkwa ọgwụ mgbe niile n'izu nke abụọ ma ọ bụ nke anọ, onye ọrịa ahụ ga-enwe mmetụta ọgwụ ọgwụ zuru oke. Ọbara ọbara ga-adị nkịtị. Ọ kwesiri iburu n’uche na mbelata ọbara mgbali n’etiti ụmụ nwoke na ụmụ nwanyị. Njikọ ịkpa ókè agbụrụ na usoro antihypertensive, nke a chọpụtara n'oge nyocha, egosighi onwe ya iji nweta nsonaazụ dị mma. "Lozap" na-eme otu ihe ahụ.

Ihe ngosi maka ojiji

Edere Lozap maka ndị ọrịa nwere ọbara mgbali elu, yana ọgwụgwọ njikọta - maka ndị ọrịa nwere ọrịa obi na-adịghị ala ala ma ọ bụrụ na enweghị ndidi ma ọ bụ enweghị ike nke ọgwụgwọ mgbe ị na-eji ndị na-egbochi ACE. A na-atụ aro ọgwụ a maka mgbochi nke ọrịa obi, gụnyere ọrịa strok, na ọnwụ na ndị nwere ọbara mgbali elu na mgbali elu ventricular. Ọrịa mamịrị na-arịa ọrịa shuga na-arịa ọrịa shuga mellitus, tinyere ọbara mgbali elu, na-ejikwa enyemaka nke "Lozap".

Usoro onunu ogwu na nhazi

N'ihe banyere ọbara mgbali elu, a na-enye “Lozap” otu ugboro kwa ụbọchị ntụtụ 50 mg. Ọ bụrụ na arụpụtaghị nsonaazụ ahụ, usoro ogwu ahụ kwesịrị okpukpu abụọ: 100 mg otu ugboro n'ụbọchị ma ọ bụ 50 mg ugboro abụọ n'ụbọchị.

Treatmentgwọ ọrịa obi na-adịghị ala ala kwesịrị ịmalite site na 12.5 mg kwa ụbọchị, otu ugboro. N'ime otu izu, a na-eji nwayọọ nwayọọ mụbaa usoro ahụ ruo 25 mg, emesịa ruo 50 mg. N'okwu a, ọ dị mkpa inyocha ọnọdụ onye ọrịa, nkwenye ya na ọgwụ.

Maka ndị ọrịa na-a aụ ọgwụ diuretics dị elu, a na-edenye ọgwụ mbido ọgwụ ahụ 25 mg. Nke nta nke nta, enwere ike ịbawanye dose ahụ. Maka ndị agadi na ndị ọrịa nwere nsogbu gbasara akụrụ, a hazigharịrị ọgwụ ahụ. Mbelata ọgịga dị mkpa maka ndị na-arụ ọrụ imeju.

A na-ewere "Lozap" otu ugboro (ma ọ bụ ugboro 2 n'ụbọchị), na-enweghị ata ata ma na-a itụ ya na nnukwu mmiri. Nwere ike were ọgwụ ahụ n'oge ọ bụla, n'agbanyeghị nri ahụ.

Nsonaazụ

N'oge ntinye nke "Lozap", mmeghachi omume nfụkasị ahụ, nchapu nke anụ ahụ, urticaria, urepu ọrịa, imi afọ, angina pectoris, myocardial infarction, vasculitis, anaemia, mgbu nkwonkwo, isi ọwụwa, hypotension, vasculitis, ọnya afọ, myalgia, nwere ike ime. akọrọ mucosa na-egbu egbu, vomiting, afọ ntachi, flatulence, ụjọ, enweghị ike, nsogbu ụra, enweghị nkụ, migraine N'ọnọdụ ndị a na-adịghị ahụkebe, ụtọ na ọhụhụ, libido belatara, enweghi ike.

Mmekọrịta na ọgwụ ndị ọzọ

Iji otu oge eji "Lozap", "Rifampicin" ma ọ bụ "Fluconazole", ọkwa plasma nke metabolite na-arụ ọrụ nwere ike ibelata. Mgbe ị na-eji ọgwụ ọgwụ na-eme ka ọnụnọ ọgwụ na-eme ka potassium pụta, ngwaahịa potassium, njikwa ọkwa ọkwa potassium dị mkpa. Belata mmetụta hypotensive nke ọgwụ "Lozap" dịka "Indomethacin" na NSAIDs ndị ọzọ. Enweghị mbelata na-arụ ọrụ mgbe ejiri digoxin, phenobarbital, warfarin, erythromycin na cimetidine.

Ozi ndi ozo

A naghị akwado iji ọgwụ a maka ndị na-arịa ọrịa imeju. Ọ bụrụ na ọ dị mkpa, jiri ọgwụ iji belata dose ma nyochaa ọnọdụ onye ọrịa.

Ọgwụ nwere ike ibute iro ụra, ndọpụ uche ma metụta ịnya ụgbọ ala na usoro mgbagwoju anya, yabụ anaghị atụ aro ka ekenye ya ndị mmadụ na ọrụ ha metụtara itinye uche ha na ntị.

Ka ị na-a theụ ọgwụ ahụ, a machibidoro ị drinkingụ mmanya na-egbu egbu egbu.

Mwepụta wepụtara ya na ihe mejupụtara

Lozap ogwu ahu, ihe omuma banyere ojiji nke aga akowara n’okpuru, nwere udi usoro ogwu ya:

• Mbadamba 12.5 mg nke ndo na-acha ọcha ma ọ bụ ude, elongated, n'ụdị ihe nkiri na shei.
• Mbadamba 50 mg ọcha ma ọ bụ ndò na-acha, nke elongated, na shei nwere notch maka ịdị mfe nke nkewa.
• Mbadamba 100 mg ọcha ma ọ bụ ndò na-acha ọcha, nke dị ogologo, na shei ahụ, yana ọkwa maka mmezi dose.

Ngwakọta ọrụ nọ n'ọrụ bụ losartan potassium na mmiri ndị ọzọ na-enweghị mmetụta ọgwụgwọ. Na shei ahụ mejupụtara ọcha sephyphilus, hypromellose, macrogol, MCC na dioxide titanium.

Mmetụta ọgwụ

Losartan bụ onye na - emegide otu ihe nnabata nke angiotensin II (subtype AT1), nke na - egbochi bradykinin ma ghara egbochi enzyme kinase II. Na-ebelata OPSS (ngụkọta akwara vaskụla), mkpokọta nke aldosterone na adrenaline na ọbara, mgbali ọbara (mgbali ọbara), nrụgide na arịa nke mgbasa akwara, na-ebelata ibu azụ, nwere mmetụta diuretic. Na-egbochi mpụta nke myocardial hypertrophy, na-eme ka nnagide mmega ahụ nwee ndị ọrịa nwere nkụda obi (nkụda mmụọ obi na-adịghị ala ala).

Hydrochlorothiazide - turezide diuretic na - egbochi mgbochi nke sodium ion, na - eme ka mmiri bicarbonate, potassium ion na phosphates dị na mmamịrị ahụ. Ọ na - ewelata ọbara ọgbụgba n'ihi mbelata nke bcc (olu na - ekesa olu), na - egbochi nrụgide nke vasoconstrictors, mgbanwe na mmegharị nke mgbidi vaskụla na mmụba na mmetụta inhibitory na ganglia.

Ihe ngbanwe

Ihe mgbochi maka ọgwụgwọ bu ihe ndi a:

• ngbaka
• ime
• oge inye ara,
• afọ ruo afọ 18 (arụpụtaghị na ịdị adị na nchekwa),
• hypokalemia na-egbochi ọgwụgwọ ma ọ bụ hypercalcemia,
• nnukwu ọrịa imeju,
• igbochi oria nke biliary tract,
• hyponatremia refractory,
• hyperuricemia na / ma ọ bụ gout,
• oke arụmọrụ gbasara akụrụngwa (CC ≤ 30 ml / min),
• hypersensitivity na akụkụ nke ọgwụ ma ọ bụ ọgwụ ndị ọzọ sitere na sulfonylamide.

Edere ya nke ọma na ndị ọrịa nwere obere akwara akwara akwara ma ọ bụ stenosis nke otu akụrụ akwara, ọnọdụ hypovolemic (gụnyere afọ ọsịsa, ọgbụgbọ), hyponatremia (ịba ụba nke hypotension ọrịa na ndị ọrịa na nri ntakịrị nnu ma ọ bụ nnu), hypochloremic alkalosis, hypomagnes , yana ọrịa anụ ahụ jikọrọ ọnụ (gụnyere SLE), ndị ọrịa nwere ọrụ imeju nwere nkwarụ ma ọ bụ nwee ọrịa imeju na-aga n'ihu, ọrịa shuga mellitus, ụkwara ume ọkụ bronchial (gụnyere akụkọ ihe mere eme), akụkọ banyere ihe nfụkasị, n'otu oge na NSAIDs, incl. Ndị na-egbochi COX-2, yana ndị nnọchi anya agbụrụ Negroid.

Jiri n'oge ime na lactation

Ihe omuma banyere iwere Lozap Plus n'oge di ime adighi, mana imara na ogwu ojoo na emetuta usoro renin-angiotensin n’ime onwa abuo na nke ato n’enwe oria nwere ike kpasu mmeghari mmepe ya na obughi onwu nwa n’ile.

Maka nke a, a na-atụ aro ịkwụsị ị theụ ọgwụ ozugbo ọ dị ime.

Site na inye ara, ị kwesịrị ịhapụ ya ma ọ bụ kwụsị ọgwụgwọ.

Usoro onunu ogwu na uzo ochichi

Ntụziaka eji eme ihe na-egosi na a na -ekwu Lozap ọnụ, n'agbanyeghị nri nri.

1. Site na nrụgide dị ukwuu (ọbara mgbali), mbido mbụ na mmezi bụ 1 mbadamba / ụbọchị. Ọ bụrụ na mgbe ị na-eji ọgwụ ahụ na ọgwụ a, ọ gaghị ekwe omume ịnweta nchịkwa ọbara zuru oke, enwere ike ịbawanye dose nke ọgwụ Lozap Plus na mbadamba abụọ. 1 oge / ụbọchị
2. Ogo kachasị nari bụ mbadamba abụọ. 1 oge / ụbọchị Na mkpokọta, enwere mmetụta hypotensive kacha mma n'ime izu 3 mgbe mmalite ọgwụgwọ.
3. Enweghị mkpa maka nhọpụta mbụ n'ime ndị ọrịa agadi.

Iji belata ihe ize ndụ nke ibute ọrịa obi na ọrịa na ndị ọrịa nwere ọbara mgbali elu na akụrụngwa hypertrophy, losartan (Lozap) ka etinyere n ’usoro izizi nke 50 mg / ụbọchị. Ndị ọrịa na-emezughị ihe mgbaru ọsọ ọbara mgbali elu mgbe ị na-eji losartan na ọgwụ nke 50 mg / ụbọchị chọrọ ọgwụgwọ na ngwakọta nke losartan na hydrochlorothiazide na obere ọgwụ (12.5 mg), nke enyere ọkwa Lozap Plus ọgwụ.

Ọ bụrụ na ọ dị mkpa, enwere ike ịbawanye dose nke Lozap Plus na mbadamba abụọ. (100 mg nke losartan na 25 mg nke hydrochlorothiazide) 1 oge / ụbọchị.

Nsonaazụ

Nnwale ndị a na-ahụ maka ọgwụgwọ nke ọgwụgwọ nke ọbara mgbali elu na losartan na hydrochlorothiazide na njikọ gosipụtara mmepe nke otu mmeghachi omume otu oge na 1% ma ọ bụ karịa ma e jiri ya tụnyere placebo - dizziness. Nsonaazụ ndị ọzọ kọrọ n'oge nkwonkwo na losartan na hydrochlorothiazide sitere na sistem na akụkụ:

• umeji na ọnya biliary: adịkarịghị - ịba ọcha n'anya,
• ụjọ usoro: na ugboro ugboro - dysgeusia,
• arịa: na ogologo oge - mmetụta orthostatic, dose-dependance,
• anụ ahụ na anụ ahụ dị n'okpuru ala: yana ugboro ugboro - ụdị anụ arụ nke lupus system nke lryus erythematosus,
• Ihe omumu na ihe omumu nke ulo a: odi otutu - ubara oru nke hepatic transaminases, hyperkalemia.

Ọzọkwa, iji Lozap gbakwunyere nwere ike ime ka mmeghachi omume dị njọ nke ihe ọ bụla na-arụ ọrụ nke ọgwụ ahụ iche.

Mmetụta ndị metụtara ya na ojiji nke hydrochlorothiazide:

• akụkụ nke ọhụụ: ugboro ugboro - xantopsia, mbelata oge ịhụ ihe anya,
• eriri afọ: akwara ugboro - ọgbụgbọ / ọgbụgbọ, afọ ntachi, afọ ọsịsa, eriri afọ, ihe na-egbu egbu, sialadenitis,
• sistem: obi akwara - vasculitis akpụkpọ, necrotic vasculitis,
• akpụkpọ anụ na subcutaneous anụ ahụ: ugboro ugboro - urticaria, fotoensitivity, necrolysis na-egbu egbu,
• imeju na ọnya biliary: ugboro ugboro - pancreatitis, cholecystitis, cholestatic jaundice,
• sistem iku ume, obi na akụkụ ahụ mmadụ: n'ime oge - ọrịa ọrịa iku ume (RDS), gụnyere ọrịa akwara umeji na ọria akpa ume,
• ọbara na sistem lymphatic: ugboro ugboro - hemolytic anaemia, aplastic anemia, leukopenia, thrombocytopenia, purpura, agranulocytosis,
• metabolism: ugboro ugboro - hypokalemia, hyperuricemia, hyponatremia, hyperglycemia, anorexia,
• dịghịzi usoro: anaphylactic mmeghachi omume ruo ujo,
• ụjọ ụjọ: ọ na-abụkarị isi ọwụwa,
• psyche: enweghi oge - ehighi ura,
• akụrụ na urinary tract: ugboro ugboro - akwara ọdịda, interstitial nephritis, glycosuria,
• sistem mọzụlụ na anụ ahụ jikọrọ ọnụ: oge ​​na - adịghị anya akwara,
• nsogbu izugbe: oge ​​na - adịghị egbu egbu, ahụ ọkụ.

Mmetụta ndị metụtara ya na iji losartan:

• dịghịzi - ihe omume nke hypersensitivity, gụnyere anaphylactic mmeghachi omume, angioedema nke glottis na larynx nwere ọnọdụ nke ihe mgbochi ikuku, ọrịre nke ihu, pharynx, ire, egbugbere ọnụ,
• akụkụ anụ ahụ na gland mammary: ugboro ugboro - dysfunction erectile, mbelata libido,
• ahu nke anya: Ugboro ugboro - obi na-ere oku n'anya, mbelata ihe anya na-ahụ anya, na-ahụ maka ọnya na-ahụ anya, na-ahụ ọhụụ.
• nti anụ ahụ na ọrịa labyrinth: ugboro ugboro - vertigo, na-akụ ntị,
• anụ ahụ na akpụkpọ anụ subcutaneous: ugboro ugboro - dermatitis, hyperemia, ihe ngbu, itching, sweating, photosensitivity, akọrọ skin, alopecia,
• imeju na traktị biliary: na-enweghị njedebe - ọgbụgba imeju,
• ọgba aghara n'ozuzu: mgbe mgbe - mgbu obi, asthenia, ike ọgwụgwụ, ugboro ugboro - ahụ ọkụ, ọzịza nke ihu, na oge na - enweghị njedebe - adịghị ike, ụdị ihe mgbaàmà,
• eriri afọ, mgbe mgbe - afọ ọsịsa, ọgbụgbọ, dyspepsia, afọ mgbu, adịkarịghị - ọgbụgbọ, gastritis, ọnụ akọrọ, afọ ntachi, flatulence, eze mgbu,
• metabolism: ugboro ugboro - gout, anorexia,
• usoro akwara na uru ahụ: oge ​​- azụ mgbu, mgbu ụkwụ, sciatica, olu mgbu, adịghị ala ala - olu mgbu na ọkpụkpụ, ọzịza nke nkwonkwo, adịghị ike ahụ, fibromyalgia, ogbu na nkwonkwo, nkwonkwo akwara, na nkwonkwo akwara, ya na ugboro ugboro - rhabdomyolysis,
• psyche: oge ​​ụfọdụ - nsogbu ehighị ụra, adịghị ala ala - enweghi ike ncheta, obi erughị ala, ọgba aghara, nsogbu ịrahụ ụra, nrọ ndị pụrụ iche, ụra ụfụ, ọgụ ụjọ, nchekasị, nchekasị,
• sistem iku ume, obi na akụkụ ahụ mmadụ: oge ​​- sinusitis, mkpọchi imi, ọrịa akụkụ nke akụkụ akụkụ okuku ume, ụkwara, adịkarịghị - rhinitis, imi, bronchitis, dyspnea, laryngitis, pharyngitis,
• ọbara na sistem lymphatic: ugboro ugboro - hemolysis, anaemia, ecchymosis, ọrịa Shenlein-Genoch, nwere ọtụtụ oge - thrombocytopenia,
• sistemu ụjọ: mgbe ụfọdụ - akpịrị ọgbụgba, isi ọwụwa, ugboro ugboro - paresthesia, oke iwe, syncope, migraine, shoor, neuropathy akụkụ,
• sisitemu akwara: akaghi aka - vasculitis, atriventricular ngọngọ II, angina pectoris, mgbu na sternum, orthostatic hypotension, mbelata ọbara mgbali, arrhythmias (tachycardia, sinus bradycardia, ventricular tachycardia, atonia fibrillation, ventricular fibrillation, heart)
• akụrụ na urinary tract: ọtụtụ mgbe - arụ ọrụ akụrụngwa arụ ọrụ, ugboro ugboro - ọrịa na - efe efe nke urinary tract, peremptory oku maka urination, nocturia,
• ọmụmụ ụlọ nyocha na akụrụngwa: oge ​​- hyperkalemia, mbelata nke ukwuu na haemoglobin na hematocrit, adịghị obere - ntakịrị mmụba na ọdịnaya nke creatinine na urea na plasma ọbara, na-adịkarị obere - mmụba na ọrụ bilirubin na hepatic transaminases, yana ugboro ugboro - hyponatremia.

Dodoụbiga ya ókè

Site na mmachi nke Lozap gbakwunyere, a na-ahụ ihe mgbaàmà ndị a: n'ihi ọdịnaya nke losartan - bradycardia, tachycardia, mbelata ọbara mgbali elu n'ihi ọdịnaya hydrochlorothiazide - mfu nke electrolytes na akpịrị.

Treatmentụbiga ọgwụ ike ókè bụ ihe mgbaàmà.Ọ dị mkpa ịkwụsị ị theụ ọgwụ ahụ, hichaa afọ ma mee ihe iji bulie nguzo mmiri-electrolyte. Site na mmụba dị ukwuu na ọbara mgbali elu, a na-egosipụta ọgwụgwọ infusion mmezi. Usoro ọgwụgwọ iji wepụ losartan adịghị arụ ọrụ. Ogo ogo hydrochlorothiazide site na hemodialysis edobeghị.

Ntụziaka pụrụ iche

Ekwesịrị iji nlezianya gwọọ ndị ọrịa nwere ọrịa angioedema n'oge gara aga.

N'ihe banyere ntụgharị uche ma ọ bụ ọnya na-adịghị ala ala, a ga-enyerịrị usoro ọgwụgwọ ọgwụ n'okpuru nlekọta nke ndị ọkachamara, ebe ọ bụ na ọ ga-ekwe omume ịbawanye ụba nke ihe ndị dị n'ọrụ nke ọgwụ ahụ na plasma ọbara, nke na-eme ka ohere nke ịdoụbiga mmanya ókè na mmetụta ọjọọ.

Lozap na Lozap gbakwunyere nwere ike ibute ọgbụgbọ, ụra, na nkụda mmụọ, nke na-emetụta ikike ịchịkwa usoro, ya mere, megide ndabere nke iji ọgwụ ndị a, a na-atụ aro ka ịhapụ ihe omume ọ bụla chọrọ nlebara anya na ọsọ nke mmeghachi omume.

Mkparịta ụka ọgwụ ọjọọ

Ngwá ọrụ ahụ nwere akụ nke ịkwalite ọrụ nke ọgwụ ọgwụ ndị ọzọ na - egbochi mmiri. A na-ahụkwa mmụba nke ndị na - ebubigaghị ókè akwara. Ojiji nke NSAIDs nwere ike ịkpasu mmebi nke ọrụ hydrochlorothiazide. Ojiji Lozap gbakwunyere na lithium na-eme ka ohere nke ịxụbiga mmanya ókè dịkwuo mma. Colestyramine na-ebelata nnabata nke hydrochlorothiazide.

Site na iji Lozap gbakwunyere na ọgwụ hypoglycemic, a chọrọ ndozi usoro onunu ogwu.

Anyị nwetara ụfọdụ nyocha nke ndị na-a theụ ọgwụ Lozap gbakwunyere:

1. Olga Aụrụ m naanị otu mkpụrụ mbadamba Lozap + (nke dọkịta nyere ya). Kwa nkeji ise, m malitere ịgba ọsọ gaa ụlọ mposi, mgbe nkeji iri abụọ gasịrị, azụ m na-egbu mgbu (o doro anya na ọ bụghị azụ m, kama akụrụ m). Mgbu ahụ enweghị ike ibugharị akwa. N'isi ụtụtụ. Aụghị m mmanya ọzọ. Mana site na Lozap dị mfe ọ dịghị ihe na-afụ ụfụ.
2. Hɔ N'afọ nke anọ, m na-a drugsụ ọgwụ ndị na-ebelata ọbara mgbali elu. Na mbu, Enap butere, ma site na ya, ukwara di ike. Dọkịta ahụ gwara Lozap. Nyere aka nke ọma. Nrụgide ahụ ghọrọ 120/70. Ma n’oge na-adịbeghị anya, amalitere m ịzaụ Lozapas + na nrụgide rịgoo elu. Taa wụsara na 180/110. Ekwesịrị m ị aụ ọgwụ ọzọ, mana ugbua Lozap. Nrụgide mgbe otu elekere gasịrị - 135/87. Anyone nweela onye nwere nsogbu nke Lozap? Kedu ihe ọ ga - esi?
3. Elena. Ọbara ọbara m na-arị elu nke ukwuu, ọ na-abụkarị mgbe ụjọ jidere m. Ozugbo ọ wụsara elu 170 n'ime otu narị, agara m kpọọ dọkịta (achọghị m ịgwọ onwe gị ọgwụ). Dọkịta dụrụ ọdụ “Lozap gbakwunyere,” iji mee ka ọbara mgbali m dị nkịtị, ọ bụ naanị ọkara mkpụrụ ọgwụ ahụ ezuru, nrụgide ahụ wee kwụsị ngwa ngwa. Ugbu a na ọgwụ m nwere mbadamba mbadamba Lozap.
4. Tatyana. A Iụrụ m ọtụtụ ihe site na nrụgide mụbara mgbe niile, na afọ 26 m enwere 140-150 mgbe niile. Ozugbo ha edepụtaghị m, edepụtara Lozap, amalitere m ị drinkingụ mmanya ... Ma ihe niile kpuchiri ọghọm, ọnya na ụfọdụ ụdị pustules. Di m machibidoro m ị drinkụ mmanya, mgbe m lakpuchara ụra, ọ bụrụ na m na-asacha ihe dị ka nkeji iri abụọ, ụra adịghị m. Akwụsịrị m ị themụ ha na ihe niile agafe. Amaghị m ihe m ga-a drinkụ ugbu a.

Echiche ndị dọkịta banyere Lozap gbakwunyere na-adị iche. N'ihi ya, ndị dọkịta na-atụle ọgwụ ndị ahụ dị mma ma, n'ihi ya, na-emeghachi omume n'ụzọ ziri ezi naanị n'okwu metụtara ọbara mgbali elu. Nke ahụ bụ, ọ bụrụ na mmadụ nwere ọbara mgbali elu, mgbe ahụ Lozap ma ọ bụ Lozap gbakwunyere nke ọma ma enwere ike iji ya mee ihe ogologo oge.

Ọ bụrụ na ọbara mgbali elu siri ike ma jikọta ya na ọrịa obi, yabụ na arụmọrụ nke Lozap dị ala. Actionme ọgwụ a ezughị 5 ruo 8 awa, n'ihi nke ndị mmadụ ga-ewerekwa ọgwụ ndị ọzọ siri ike. N'ihi ya, n'ọnọdụ ndị dị otú a, ọ bụ ihe ezi uche na-adịghị na ya iji Lozap, ebe ọ bụ na ịkwesịrị ilekwasị anya ozugbo na ọgwụ ndị ọzọ dị ike antihypertensive, dịka ọmụmaatụ, ndị na-egbochi beta.

Anakpụrụ nke analogues nke na-arụ ọrụ:

• Ngọngọ
• Brozaar
• Vasotens,
• Vero-Losartan,
• Zisakar
• Cardomin Sanovel,
• Karzartan
• Cozaar
• Lakea
• Lozarel
• Losartan
• Potassium Losartan,
• Losartan anụ ahụ,
• Losartan ọgaranya
• Losartan teva
• Lorista
• Losacor
• Presartan
• Nkọwapụta.

Tupu iji analogues, gwa dọkịta gị.

Ngwakọta, iche na ụdị ntọhapụ

Na ahịa ọgwụ, enwere ụdị ọgwụ abụọ dị - ndị a bụ Lozap na Lozap Plus. Varietiesdị ndị a dịgasị iche na Lozap nwere naanị otu akụrụngwa na-arụ ọrụ, Lozap Plus nwekwara abụọ. Ọzọkwa, isi akụrụngwa nọ na Lozap na Lozap gbakwunyere bụ otu, ihe nke abụọ na Lozap gbakwunyere bụ, ihe ndị ọzọ na - eme ka ihe mbụ pụta. N'isiokwu a, anyị ga-atụle ụdị ọgwụ abụọ ahụ, ebe ha nwere otu mmetụta ahụ, ka egosiri maka iji otu ọnọdụ, wdg.

Ma Lozap na Lozap Plus dị n'ụdị usoro onunu ogwu - nke a mbadamba onụ. Lozap dika ihe eji eme ihe losartan, na Lozap gbakwunyere - losartan na hydrochlorothiazide. Ihe losartan ahụ bụ ihe na-egbochi enzyme angiotensin na-agbanwe (ACE), hydrochlorothiazide bụ ọgwụ diuretic. N'ihi ya, losartan na-ebelata ọbara mgbali ma na-ebelata ibu dị na obi, hydrochlorothiazide na-ewepụ mmiri dị ukwuu n'ahụ, na-eme ka mmetụta nke ihe mbụ ahụ pụta. Ya mere, Lozap gbakwunyere nwere mmetụta hypotensive siri ike ma e jiri ya tụnyere Lozap, n'ihi na o nwere ngwakọta nke ihe mejupụtara, ọ bụghị otu ihe.

Na ụkpụrụ, e guzobere Lozap Plus maka iji ya mee ihe nfe, ebe ọ bụ na a na-ejikarị ihe eji eme ihe iji mee ka mmetụta ya dị na ndị na-egbochi ACE. Ndị na-emepụta ihe jikọtara ngwongwo ndị a n'otu ọgwụ, nke dị mma maka onye kwesịrị ịnara naanị otu mbadamba, ọ bụghị abụọ, atọ, wdg.

Lozap dị na usoro atọ - 12.5 mg, 50 mg na 100 mg nke losartan kwa mbadamba. Lozap Plus dị na usoro onunu ogwu - 50 mg nke losartan + 12.5 mg nke hydrochlorothiazide. Mpekere iri abụọ na ise (5 mg mg) mbadamba ụrọ nwere ọdịdị biconvex nke ukwuu, na-acha ọcha ma ọ bụ ihe fọrọ nke nta ka ọ bụrụ ọcha ma dị na ngwugwu 30, 60 na 90. Mpempe akwụkwọ Lozap 50 mg na 100 mg bụ biconvex nke ukwuu, na-acha ọcha ma ọ bụ ihe fọrọ nke nta ka ọ bụrụ nke na-acha ọcha, dị ize ndụ n'akụkụ abụọ ma dịnụ na ngwugwu 30, 60 na 90. Lozap gbakwunyere na mbadamba nkume ndị siri ike, na-ese na odo dị ọkụ, dị ize ndụ n'akụkụ abụọ ma dị na ngwugwu 10, 20, 30 na 90.

Omume Lozap

Mmetụta ọgwụgwọ Lozap bụ belata ọbara mgbali ma belata ibu ahụ n’obi. Enyere mmetụta a nke ọgwụ ahụ n'ihi ikike ya ịkwụsị ọrụ nke enzyme angiotensin-na-agbanwe (ACE), na-eme ka nchegharị nke angiotensin nke m bụrụ angiotensin II. Ọ bụ n'ihi eziokwu ahụ na Lozap gbochiri enzyme ahụ, ọ bụ nke otu nke ndị na - egbochi ACE.

N'ihi ihe nke Lozap, etolite angiotensin nke II abụghị ahụ mmadụ - ihe na - egbochi arịa ọbara, ma, yabụ, na - eme ka ọbara mgbali elu. Ọ bụrụ n ’imechi angiotensin nke Abụọ akpọchi, mgbe ahụ arịa ndị ahụ anaghị warara, ọbara ọgbụgba na-ebelata ma ọ bụ na-adịgide n’ókè kwesịrị ekwesị. Na-emegide usoro iji Lozap eme ihe mgbe niile, ọbara mgbali na-ebelata ma a na-edebe ya ka ọ kwesịrị ịdị. Ọzọkwa, a na-ahụkarị mmetụta mbụ hypotensive ugbua 1 - awa 1.5 mgbe ị theụsịrị ọgwụ ahụ wee dịgide maka otu ụbọchị, mana iji nọgide na-agbada nrụgide, ịkwesịrị ị drinkụ ọgwụ ahụ ma ọ dịkarịa ala izu anọ na ise. Lozap iji belata nrụgide dị nnọọ irè na ndị agadi na ndị ọrịa na-eto eto na-arịa ọbara mgbali oke akpụ.

N'ihi mmụba nke arịa ọbara, Lozap na-ebelata ibu na obi, nke dị mfe ịkwalite ọbara site na ha. Site na mmezi nke obi, ọgwụ a na-eme ka nnabata nke anụ ahụ na nke mmetụta uche na-emetụta ndị mmadụ na-arịa ọrịa obi na-adịghị ala ala.

Lozap na-emekwa ka ọbara nwee ike ibute n’obi na ike ọbara gbasara akụrụ, ya mere eji eme ya nke ọma n’ịgwọ ọrịa obi na-adịghị ala ala na ọrịa nephropathy.

Lozap jikọtara nke ọma na ọgwụ ndị ọzọ na - egbochi akụrụngwa ma nwee mmetụta ọria dijitalụ, n'ihi na anụ ahụ anaghị ejigharị ọnya na - emepụtaghị edema.

Lozap gbakwunyere nwere mmetụta hypotensive karịa ka e jiri ya tụnyere Lozap, ebe ọ bụ na hydrochlorothiazide diuretic gụnyere na ihe mejupụtara ya na-eme ka mmetụta nke onye na-egbochi ACE kwụsị.

Iche iche, ekwesiri iburu n'uche na Lozap na-abawanye excretion nke uric acid ma, ya mere, na-ebelata ntinye uche ya na ọbara.

Mgbe ị kwụsịrị ị Loụ Lozap na Lozap, ọrịa “ngbanwe” adịghị etolite.

Ntụziaka maka iji Lozap

A pụrụ iwere mbadamba Lozap nke usoro ọgwụ ọ bụla n'agbanyeghị nri, na-elo ya kpamkpam, na-enweghị ata ma ọ bụ na-akụri ya n'ụzọ ọ bụla, mana site na obere mmiri mmiri (ọkara otu iko zuru ezu). Ebe ọgwụ ahụ nwere mmetụta na-adịgide adịgide, a na-ewere ọgwụ niile dị mkpa kwa ụbọchị otu ugboro, ya bụ, mbadamba mmanya na-egbu mmanya otu oge kwa ụbọchị. Ọ dị mma ị theụ ọgwụ kwa ụbọchị n'otu oge, ọkacha mma na mgbede.

Ngwọta nke Lozap na-ekpebi ọrịa nke eji ọgwụ a maka ya. Usoro ọgwụgwọ na-abụkarị ogologo - site na ọtụtụ ọnwa ruo ọtụtụ afọ. A na-ekpebi oge ọgwụ ga-anọ n'otu n'otu, dabere na nha nke nrụpụta / nsonaazụ ya.

N'ihe banyere ọbara mgbali elu, a na-atụ aro Lozap ka ọ were 50 mg otu ugboro n'ụbọchị maka ogologo oge. N'ọnọdụ ụfọdụ, ọ bụrụ na ọ dị mkpa iji nweta nnukwu ogo nke ọgwụgwọ ọgwụgwọ, ị nwere ike ime ka ọgwụ ahụ dịkwuo 100 mg. A na-ewere Lozap na dose nke 100 mg otu ugboro n'ụbọchị (ozugbo 100 mg), ma ọ bụ ugboro 2 n'ụbọchị maka 50 mg. Ọbara mgbali elu na-ahụkarị ka izu atọ gachara ise ka ị .ụsịrị ọgwụ. Ebe ọgwụ ahụ anaghị akpata ọrịa ịdọrọ ma jiri nwayọ mee ihe, ị nwere ike ịmalite were ya zuru oke ọgwụgwọ - 50 mg kwa ụbọchị.

N'ime nkụda obi na-adịghị ala ala, a na-atụ aro Lozap ịmalite ịmalite 12.5 mg otu ugboro n'ụbọchị. N'oge usoro ọgwụgwọ a, a na-a theụ ọgwụ ahụ otu izu. Mgbe ahụ usoro onyonyo okpukpu abụọ ma were ọgwụ ahụ na 25 mg otu ugboro kwa ụbọchị maka izu ọzọ. Mgbe nke a gasịrị, a na-enyocha ịdị irè nke ọgwụ a ma ọ bụrụ na ogo ọrụ ahụ ezughi oke, a na-agbakwunye usoro ahụ okpukpu abụọ - ruo 50 mg otu ugboro n'ụbọchị. Mgbe a na-ebute ọgwụ nke Lozap na 50 mg kwa ụbọchị, ọ naghị abawanye ụba ma na-ewere ọgwụ ahụ n'ọtụtụ. Ọ bụrụ na ọgwụ a na-a aụ ọgwụ nke 50 mg adịghị arụ ọrụ, ị ga-eji ya dochie ya, ma emekwala ka usoro ahụ dịkwuo. Ọ bụrụ na usoro onunu ogwu nke 25 mg kwa ụbọchị dị irè, mgbe ahụ ịkwesịrị ị theụ ọgwụ ahụ na ego a, na-enweghị ịba ụba ya na 50 mg.

Mgbe ị na-eji ọgwụ ahụ iji belata ihe ize ndụ nke ịmalite ọrịa obi na belata ọnwụ na ndị mmadụ na-arịa ọbara mgbali elu ma ọ bụ mgbakwunye ventricular hypertrophy, ịkwesịrị ịmalite Lozap 50 mg otu ugboro n'ụbọchị. Mgbe izu abụọ na atọ gachara ọgwụ mbido ọgwụ, a na-enyocha ịdịmma ya. Ọ bụrụ na nke a zuru ezu, a na-atụ aro ka ị nọgide na-ewere Lozap 50 mg otu ugboro kwa ụbọchị ruo ogologo oge. Ọ bụrụ na arụmọrụ ezughi oke, mgbe ahụ, ma etu esi ewepụta Lozap ka ọ bụrụ 100 mg, ma ọ bụ ekwesịrị ịhapụ itinye Lozap ka ọ gbanwee, mana ekwesịrị ịgbakwunye hydrochlorothiazide 50 mg kwa ụbọchị. Enwere ike iwere Lozap na dose nke 100 mg otu ugboro n'ụbọchị, ya bụ, 100 mg niile n'otu oge, ma ọ bụ ugboro abụọ n'ụbọchị (50 mg n'ụtụtụ na mgbede).

Iji nọgide na-arụ ọrụ akụrụ na ọrịa mellitus na-arụ ọrụ nkịtị, jikọtara ya na ọbara mgbali elu, n'oge mmalite nke Lozap na-ewere 50 mg otu ugboro kwa ụbọchị, na mgbe izu 1 ruo izu abụọ, na-abawanye usoro onunu ogwu ka 100 mg kwa ụbọchị. Ọ bụ 100 mg kwa ụbọchị ka a ga-ewere Lozap maka ọgwụgwọ ogologo oge nke nsogbu akụrụ. Enwere ike ị Aụ ọgwụ ogwu nke 100 mg nke Lozap n'otu oge ma ọ bụ ekewa abụọ n'ime doses - 50 mg 2 ugboro n'ụbọchị.

Ọ bụrụ na a na-a aụ ya n’otu oge, ma ọ bụ na-arịa mmadụ ị deụ mmiri (dịka ọmụmaatụ, mgbe ọgbụgbọ, afọ ọsịsa, wdg), mgbe ahụ, a ga-ebelata oke onunu ogwu nke Lozap ka ọ bụrụkarị 25 mg kwa ụbọchị.

Ndị okenye (karịa afọ 65) kwesịrị iburu Lozap na usoro ndị a na-emebu, ekwughị ka ọ belata ha. Agbanyeghị, ndị mmadụ karịrị afọ iri asaa na ise na-ata ahụhụ site na ọrịa imeju, akpịrị ịkpọ nkụ, na ịba ọcha n'anya kwesịrị ị theụ ọgwụ ahụ n'ime ọgwụ 25 mg otu ugboro n'ụbọchị. Nwere ike iwelie onunu ogwu maka ụdị ndị a ruo ogo 50 mg kwa ụbọchị.

Usoro kachasị anabata nke Lozap kwa ụbọchị bụ 150 mg.

Lozap Plus - ntuziaka

A na-ewere mbadamba okwu ọnụ, n'agbanyeghị nri, na-elo ha niile, na-akọghị ya akọ, na-ata ma ọ bụ kagbuo n'ụzọ ọ bụla ọzọ, mana obere mmiri ka dị (ọkara otu iko zuru ezu).

Site n'ọbara mgbali elu, ọgwụ malitere ozugbo were mbadamba 1 otu ugboro n'ụbọchị. Mgbe izu atọ ruo ise gachara, chọpụta uru ọgwụ jiri uru ọbara ọgbụgba bara. Ọ bụrụ na nrụgide ahụ agbadala n'ụkpụrụ ndị a na-anabata, mgbe ahụ Lozap gbakwunyere ga-ewere ya na usoro a, ya bụ, 1 mbadamba 1 n'otu oge kwa ụbọchị. Ọ bụrụ na, mgbe izu atọ ruo ise ga-amalite ọgwụ ahụ, enweghi ike iweta nrụgide ahụ ka ị nabata ụkpụrụ a na-anakwere, mgbe ahụ, a ga-abawanye usoro ịbanye na mbadamba 2, nke a ga-ewererịrị n'otu oge.

Iji belata ihe ize ndụ nke ọrịa obi na ọnwụ na ndị mmadụ na-arịa ọbara mgbali elu na akwara ọbara obi ventricular nke obi, a ga-ewere Lozap 1 mbadamba otu ugboro n'ụbọchị. Ọ bụrụ na mgbe izu atọ atọ na ise gachara mmalite nke ike ọgwụgwọ ọgwụgwọ ezughi oke, mgbe ahụ, usoro onunu ogwu nke Lozap gbakwunyere ma kwesiri iji mkpụrụ mbadamba abụọ otu ugboro kwa ụbọchị.

Oke kacha anabata nke Lozap gbakwunyere kwa ụbọchị bụ mbadamba abụọ.

Ndi okenye kwesiri iwere Lozap Plus na usoro kwesiri ekwesighi iwelata ha.

Jiri n’oge ime na inye nwa ara

A naghị akwado Lozap na Lozap maka ojiji n'oge ọnwa atọ mbụ nke afọ ime (rue ma gụnyere izu nke iri na atọ nke oge ime), na nke abụọ na nke atọ, ọgwụ ndị ahụ apụtaghị ọgwụ niile.

Nke a pụtara na site na mmalite ruo izu nke iri na atọ nke ịtụrụ ime ọ ka mma ịhapụ ị ofụ ọgwụ, mana ọ bụrụ na enwere mkpa ọ bụla, mgbe uru doro anya gafere karịa ihe egwu niile, enwere ike iji Lozap ma ọ bụ Lozap gbakwunyere.

Malite na izu nke iri na anọ nke afọ ime ruo n’ọmụmụ Lozap na Lozap, gbakwunyere na-egbochi imebi. Nke a bụ, ekwesighi ị drugsụ ọgwụ n'ọnọdụ ọ bụla n’oge afọ II na III nke afọ ime.

Womenmụ nwanyị na-ewere Lozap ma ọ bụ Lozap gbakwunyere ndị na-eme atụmatụ ime kwesịrị ịmalite n'oge a ị takingụ ọgwụ ndị ọzọ antihypertensive ndị e nyere ohere iji mụọ nwa (dịka ọmụmaatụ, Nifedipine, wdg). Ọ bụrụ na ịtụrụ ime mere emeghị atụmatụ, mgbe ahụ ịkwesịrị ịghara Lozap ma ọ bụ Lozap gbakwunyere ozugbo ọ bịara mara banyere afọ ime ahụ.

Lozap na Lozap gbakwunyere, mgbe ejiri ya n’oge nke abụọ na nke atọ nke afọ ime, nwere nsị na-egbu egbu na nwa ebu n’afọ, na-eme ka ọrụ ezumike n’akwụsịghị akwụsị, na-ebelata oke ọkpụkpụ nke okpokoro isi ma na-akpalite nguzobe nke oligohydramnios.N'ihi ihe a, Lozap ma ọ bụ Lozap gbakwunyere nwere ike ịkpalite ọdịda akụrụ, hypotension na hyperkalemia n'ime nwa amụrụ ọhụrụ. Lozap gbakwunyere, mgbe ejiri ya mee n’oge afọ ime, nwere ike kpalite mmebi nke ọbara ọgbụgba na -emebi ihe ma nwee mmebi nke mmiri mmiri, yana jaundice na nwa ebu n’afọ na nwa amụrụ ọhụrụ.

Yabụ, ọ bụrụ na n'ihi ihe ụfọdụ, nwanyị dị ime n’oge ọ dịkarịa ala, buru Lozap ma ọ bụ Lozap Plus, a ga-eme nyocha nke nwa ebu n’afọ n’oge iji chọpụta mmekpa ahụ akụrụ na iwepu ọkpụkpụ nke okpokoro isi. Ekwesịrị ka ndị dọkịta nyochaa ụmụ amụrụ ọhụụ ụmụ nwanyị na-ewere Lozap ma ọ bụ Lozap Plus n'ihi nnukwu nsogbu hypotension (ọbara mgbali ala).

Ekwesighi iji Lozap na Lozap gbue azụ ara, ebe ọ bụ na enwere ike ịpụpụ ọgwụ mmiri ara ehi ma nwee mmetụta ọjọọ n'ahụ ahụ nwata ahụ. Yabụ, ọ bụrụ na ọ dị mkpa iji Lozap ma ọ bụ Lozap gbakwunye, ị ga-ajụ ị breastụ ara ma nyefee nwa ahụ ka ngwakọta anụ.

Analogs Lozap

Lozap na Lozap gbakwunyere na ahịa ọgwụ nke mba CIS nwere ụdị analogues abụọ - ndị a bụ mmekorita na, n'eziokwu, analogues. Mmeghari gunyere ogwu nke nwere ezigbo ihe aru oru dika Lozap na Lozap gbakwunyere. Analogues gụnyere ọgwụ nwere ihe ndị ọzọ na - arụ ọrụ, mana ha nwere ụdị ọgwụgwọ ahụ na Lozap na Lozap gbakwunyere. Na ụkpụrụ, analogs nke Lozap bụ ọgwụ nke otu nke ACE inhibitors, na Lozap gbakwunyere bụ ndị na - egbochi ACE na mgbakwunye.

E gosiputara Lozap na Lozap okwu na tebụl.

Ana-egosikwa Analogs nke Lozap na Lozap na tebụl.

Russian analogues Lozap

Ngosipụta na analogues nke Lozap na Lozap gbakwunyere mmepụta Russia ka egosipụtara na tebụl.

Otutu nyocha banyere Lozap bụ ihe dị mma (site na 85 ruo 90%), nke a bụ n'ihi oke ọgwụ dị n'ịbelata na ịnọgide na-enwe ọkwa ọbara ọ bụla na-anabata. Nyocha ndị ahụ gosipụtara na Lozap dị irè ọbụlagodi n'ọnọdụ ebe ọgwụ ndị ọzọ na-enweghị ike ịnagide ọrụ iwetulata ala na iwelie ọkwa ọbara dị ala karịa.

Nyocha na-ezighị ezi banyere Lozap dị ole na ole ma na-akpata ya, dịka iwu, site na adịghị ike nke ọgwụ ahụ n'otu ikpe. Na mgbakwunye, enwere nyocha na-adịghị mma banyere ọgwụ ahụ na-emetụta nsonaazụ ndị ọzọ na-anabata, ọdịdị nke manyere ịhapụ iji Lozap.

Lozap Plus - nyocha

Otutu nyocha banyere Lozap gbakwunyere ihe ziri ezi (karịa 90%), nke bụ n'ihi ịdị irè nke ọgwụ. Yabụ, na nyocha a gosiri na Lozap gbakwunyere belata ọbara mgbali n'ụzọ dị mma ma na-eme ya ka ọ bụrụ ụkpụrụ ziri ezi. Ọzọkwa, nsonaazụ nke ọgwụ ahụ dị ogologo, nke na-enye gị ohere ị itụ ya otu ugboro n'ụbọchị, nke a dịkwa mma.

Nyocha na-ezighị ezi banyere Lozap gbakwunyere, dịka iwu, ọ bụ nsonaazụ ya, bụ nke siri ike ịnabata ma manye ịhapụ ị theụ ọgwụ ahụ. Na mgbakwunye, enwere nyocha ndị mmadụ na-egosi na ọnụahịa ọnụahịa / arụmọrụ adịghị oke oke.

Lozap - nyocha nke ndị dọkịta

Echiche ndị dọkịta banyere Lozap na Lozap gbakwunyere na-adị iche. N'ihi ya, ndị dọkịta na-atụle ọgwụ ndị ahụ dị mma ma, n'ihi ya, na-emeghachi omume n'ụzọ ziri ezi naanị n'okwu metụtara ọbara mgbali elu. Nke ahụ bụ, ọ bụrụ na mmadụ nwere ọbara mgbali elu, mgbe ahụ Lozap ma ọ bụ Lozap gbakwunyere nke ọma ma enwere ike iji ya mee ihe ogologo oge.

Ọ bụrụ na ọbara mgbali elu siri ike ma jikọta ya na ọrịa obi, yabụ na arụmọrụ nke Lozap dị ala. Actionme ọgwụ a ezughị 5 ruo 8 awa, n'ihi nke ndị mmadụ ga-ewerekwa ọgwụ ndị ọzọ siri ike. N'ihi ya, n'ọnọdụ ndị dị otú a, ọ bụ ihe ezi uche na-adịghị na ya iji Lozap, ebe ọ bụ na ịkwesịrị ilekwasị anya ozugbo na ọgwụ ndị ọzọ dị ike antihypertensive, dịka ọmụmaatụ, ndị na-egbochi beta.

Illsgwọ maka Lozap nsogbu: ntuziaka maka ojiji

Dịka anyị kwurula, otu ụdị nrụgide nke Lozap bụ mbadamba. A na-emepụta ọgwụ ahụ n'ọtụtụ usoro ọgwụ: 12.5, 50 na 100 mg. Mbadamba ụrọ ahụ nwere ọdịdị biconvex siri ike, na-acha ọcha, na-emepụta n'ime blisters Nke 30, 60, 90. E nwere ngwá ọrụ ọzọ dị irè - Lozap gbakwunyere. Ọgwụ a nwere ihe okike ndị yiri ha, n'adịghị ka mbadamba ụdọ sitere na nrụgide, Lozap dị irè karịa. Nke a bụkwa n'ihi eziokwu na ngwakọta nke Lozap gbakwunyere, na mgbakwunye na akụrụngwa na-arụ ọrụ nke losartan potassium, gụnyere hydrochlorothiazide, nke na-enyere aka wepu oke mmiri, yana welie mmetụta hypotensive nke akụkụ mbụ.

Ọgwụ maka nrụgide Lozap edepụtara maka ọgwụgwọ:

• ọbara mgbali ike
• ọrịa obi na-adịghị ala ala (ọgwụgwọ ọgwụgwọ),
• ọrịa mamịrị nephropathy.

Na mgbakwunye, a na-enye ọgwụ ọgwụ maka ndị nwere nnukwu ihe ize ndụ nke CVS, na ọrịa strok, yana iji belata ọnwụ n'etiti ndị ọrịa na-arịa ọbara mgbali elu na oke ventricular hypertrophy.

Illsgwọ maka nsogbu Lozap na-contraindicated na ndị mmadụ na ọnụnọ nke: n'otu ekweghị ibe nọrọ, akụrụ odida, anuria, nnukwu nsogbu ke ọrụ nke akụrụ, hypoglycemia, hypercalcemia, obstructive ọrịa nke biliary tract, cholestasis, gout.

Ndị mmadụ na-ata ahụhụ site na:

• ọbara mgbali ala
• Ọrịa ọrịa obi,
• arrhythmias,
• ọrịa shuga
• myopia ma ọ bụ glaucoma,
• ọrịa anụ ahụ,
• ike obara nke obara,
• imeju ma ọ bụ akụrụ dara, were oke nlezianya were ọgwụ ahụ.

Na mgbakwunye, ndị toro eto, na ndị nwegogiri akụrụ, yana ndị edepụtara iji NSAIDs, dịka ọmụmaatụ, Nimesulide, Ibuprofen, Nurofen, jiri nlezianya họrọ usoro onunu ogwu na usoro.

A naghị atụ aro ka eji ọgwụ ahụ maka ụmụ nwanyị dị ime na ndị na-enye nwa ara, yana ụmụaka. Ogwu nwere ike inwe mmetụta ọjọọ n’ nwa ebu n’afọ.

Nnabata ndị na-ekwesịghị ekwesị, ịhapụ irubere onunu ogwu nke dọkịta na-eleta anya, ma ọ bụ nke kadị njọ, nwere oke ọghọm. Ya mere, tupu ịmalite ị thisụ ọgwụ a, gakwuru onye ọkachamara ruru eru ma mụọ ntuziaka.

N'ihe banyere oke ị theụ ọgwụ, ọgwụ ndị na-esonụ nwere ike ịpụta: akpọnwụ akpọnwụ, ida, nkụda mmụọ na nkụda mmụọ, ikike mmiri na-adịghị mma, mbelata ọbara mgbali elu, yana tachycardia.

Ọ bụrụ na ịdoụbiga ihe oke ókè, a na-eme ọgwụgwọ ọrịa Symptomatic iji nyere aka mee ka ahụ gị nọgide na-arụ ọrụ. Ọ bụrụ, n’ihi ị theụ ọgwụ, mgbali ahụ agbadata nke ukwuu, a ga-atọrịrị onye ọrịa ahụ n’elu mbara ma n’otu oge ahụ bulie njedebe ụkwụ. Ọ bụrụ na enwere mkpa, a na-enye onye ọrịa iwu iwebata saline ma ọ bụ ọgwụ ọmịiko. Ihe omume ndị a ga - enyere aka n'ịhazi ọbara mgbali elu. Iji wepu ọgwụ ahụ n'ahụ ahụ ozugbo enwere ike, etinyere ya ọgwụ diuretics.

Na mgbakwunye, n'oge ọgwụgwọ na Lozap, ọdịdị nke mmetụta ndị sitere na:

• sistem hematopoietic: anaemia, eosinophilia, thrombocytopenia,
• ọgụ ọgụ: itching na rashes, edere Quincke, photoensitization, urticaria,
• CNS: sciatica, ọgba aghara, neuropathy, jijiji, ahụ mkpọnwụ, ehighị ụra, ọgbụgbọ, ọrịa, ịda mba, nchekasị,
• STS: sensations nke obi onye obi, nkụda mmụọ, arrhythmias, hypotension, epistaxis, orthostatic hypotension, bradycardia, mgbochi nke isi II, nkụchi obi,
• usoro iku ume: dyspnea, mgbu obi, bronchitis, pharyngitis, laryngitis, imu imi, sinusitis, mkpụmkpụ ume, ụkwara, imi mkpọchi,
• Ọkpụkpụ afọ: mgbu n'ime epigastrium, nsogbu akwara (afọ ọsịsa ma ọ bụ afọ ntachi), xerostomia, gastritis, ịba ọcha n'anya, ọgbụgbọ, ọgbụgbọ, belching, flatulence, bowel mgbochi,
• sisitemu mkpụrụ osisi: mmebi n’ime arụ akụrụ, enweghi ike, akụrụ gbasara ịba mba, mbelata libido, nocturia.

Ọ bụrụ n ’akara ndị dị n’elu egosi, gwa dọkịta gị ozugbo.

Ọgwụ Lapoz maka nrụgide: otu esi etinye, mmekọrịta ya na ọgwụ ndị ọzọ

Enwere ike iji ọgwụ Lozap maka nrụgide n'agbanyeghị nri. Erere mbadamba ihe nile, ọ dighi nkpisi ma-ọli. A ga-eji mmiri kwụrụ ọgwụ a. Ebe ọ bụ na ọgwụ Lozap maka nrụgide nwere mmetụta dị ogologo oge, a na-ewere usoro ọgwụgwọ kwa ụbọchị na otu usoro, ya bụ, a na-edezi iji otu mbadamba otu ugboro n'ụbọchị. Ọ ka mma iji ngwaahịa ahụ kwa ụbọchị n'otu oge na mgbede.

Ọ bụ dibịa na-eleta hotara oke ọgwụ na usoro ọgwụgwọ ahụ, dabere na ọrịa ahụ. Standardkpụrụ ọkọlọtọ, dịka iwu, dị ogologo - site na ọnwa ruo ọtụtụ afọ.

A họọrọ oge ọ ga-eji Lozap gwọọ mmadụ n'otu n'otu, na ntinye echiche dị mkpa maka ịdị irè yana nsonaazụ ndị ọ ga-ekwe omume.

1. Maka ọgwụgwọ nke ọbara mgbali elu, a na-enye ọgwụ mgbochi ọgwụ iri ise ka ọ bụrụ otu ugboro kwa ụbọchị. Ọ na-agwọ ọrịa a ogologo oge. Mgbe ụfọdụ, iji rụpụta nsonaazụ ka mma, a na-abawanye usoro onunu ogwu rue otu narị milligrams. N'ime usoro a, a na-a theụ ọgwụ ahụ otu ugboro ma ọ bụ ugboro abụọ n'ụbọchị, 50 mg nke ọ bụla.
   Mbelata ọbara mgbali ọbara mgbe ị afterụ ọgwụ Lozap maka nrụgide ka achọpụtara, dịka iwu, mgbe ọnwa gachara ọgwụ a. Ebe ọ bụ na ọgwụ anaghị akpalite ọrịa ịdọrọ, mmetụta ya dị obere, ọgwụgwọ nwere ike ịmalite ozugbo site na iji ọgwụ zuru ezu - milligrams iri ise kwa ụbọchị.
2. Iji gwọọ ọrịa dị ka nkụda obi, a na-edenye ọgwụ 12.5 mg otu ugboro n'ụbọchị. Ọgwụ a ga-a doseụ a ga-ewere otu izu. Ọzọkwa, usoro ọgwụgwọ ahụ okpukpu abụọ. A na-atụ aro iri abụọ na ise (25 mg) otu ugboro n'ụbọchị. Mgbe ahụ, a na-enyocha ịdị irè nke ọgwụ ahụ, ọ bụrụ na egosighi mmetụta ya, ọnụọgụ ahụ na-abawanye ruo milligrams iri ise. Nke a na usoro onunu ogwu kacha. Ọ bụrụ na mgbe mmụba na ọnụọgụ nsonaazụ ahụ ka anaghị ekwupụta ya, onye ọzọ dochie ọgwụ ahụ. N'okwu ahụ mgbe ọgwụ 25 mg dị irè, ọ naghị edozi ya.
3. Iji belata ohere nke ọrịa CCC, yana iji belata ọnwụ n'etiti ndị ọrịa nwere ọbara mgbali elu na aka ekpe ventricular hypertrophy, a na-enye milligrams iri ise nke ọgwụ Lozap maka nrụgide otu ugboro n'ụbọchị.. Mgbe ọkara ọnwa gachara, chọpụta mmetụta. Ọ bụrụ na o zuru, usoro ọgwụgwọ ga-agbatịkwu ogologo oge. Ọ bụrụ na mmetụta a leghaara anya, a na-abawanye ọnụọgụ ahụ ruo 100 mg kwa ụbọchị. Mgbe ụfọdụ ha na - eme ihe dị iche iche - ha na - atụzi ọgwụ njikọta: 50 mg nke Lozap na - ahapụ 50 mg nke hydrochlorothiazide.
4. Iji nọgide na-arụ ọrụ nkịtị nke usoro urinary na ọrịa shuga gbagwojuru anya na ọbara mgbali elu, a na-atụkwa milligrams iri ise nke ọgwụ maka otu ụbọchị izu abụọ.. Na-esote, a na-abawanye ọgwụ ahụ na 100 mg. Maka ọgwụgwọ ogologo oge nke nsogbu sitere na urinary system, a na-enye Lozap na usoro onunu ogwu nke 100 mg otu ugboro kwa ụbọchị.

Ọ bụrụ na enyere onye ọrịa ahụ ọgwụ ọgwụ siri ike, ya ewere Lourep ya na Lozap, ma ọ bụ nwee akpịrị ịkpọ nkụ, dịka ọmụmaatụ, afọ ọsịsa ma ọ bụ vomiting, a na-ebelata ọgwụ ahụ ka ọ bụrụ 25 mg kwa ụbọchị. E nyere ndị okenye ọgwụ ka esi eji ọgwụ eme ihe na usoro a na-emebu, ọ naghị ebelata ma ọ bụ abawanye. A na-ahụta ogo kachasị anabata Lozap - milligrams 150.

A na - egbochi ọgwụ a n'afọime na HB. Aremụ nwanyị na-a medicineụ ọgwụ a ma na-eme atụmatụ ịtụrụ ime ka a na-agwa ka ha gaa hụ dọkịta iji dochie ọgwụ ahụ. Ọ bụrụ na atụghị ị conceụ ọgwụ ahụ, ị ​​ga-ezere ya.

Lozap nwere mmetụta dị njọ na nwa ebu n’afọ, na-akpasu arụmọrụ ezighi ezi ọrụ, na-emekwa ka iwepu ọkpụkpụ nke isi ya. Theakingụ ọgwụ n'oge afọ dị na mmepe nke ọdịda akụrụ, hypercalcemia na hypotension na nwa amụrụ ọhụrụ.

Womenmụ nwanyị ndị na-enye nwa ara kwesịrị ị drunkụ ọgwụ. Ngwunye ndị nọ n'ọrụ nwere ike ịbanye na mmiri ara ehi ma nwee mmetụta ọjọọ n'ahụ ahụ nwa ahụ. N'okwu a, ha na-edochi ọgwụ, ma ọ bụ gbanwee na ngwakọta nke wuru.

Ọ bụ naanị ndị ọkachamara ruru eru ka a ga-eji ọgwụ a mee. Ejila onwe gi ogwu. Mmetụta dị n'ahụ ahụ nke ọgwụ Lozap nwere ike ịdị iche, mana ọ na-emebikarị, ọkachasị ma ọ bụrụ na enyere iwu ka ewere ya n'ụzọ ndị ọzọ. Ugbu a karia ọgwụ banyere:

• mgbe ị na-etinye Lozap na Fluconazole ma ọ bụ Rifampicin, mbelata nke ịta ihe Lozap dị n'ọrụ,
• mgbe ị na-ewere Lozap na diuretics, karịsịa Veroshpiron ma ọ bụ Amilorid ma ọ bụ nkwadebe potassium - Asparkam, Panangin, mmụba nke potassium na ọbara ga-ekwe omume,
• na-ewere Lozap yana nkwadebe lithium ejiri nwayọ nwayọ na iwepụ lithium n'ahụ,
• site na iji njikọta nke Lozap na ọgwụ ndị ọzọ na-ebelata nrụgide (Atenolol, Metoprolol), a na-eme ka mmetụta nke beta-blockers dịkwuo mma,
• n'otu oge iji ọgwụ ọjọọ eme ihe na ajụjụ na NSAIDs (Ibuprofen, Aspirin, Ketanov) bụ ibelata arụmọrụ nke Lozap yana oke ihe ize ndụ nke ịmalite ọrịa gbasara akụrụ,
• na-ewere Lozap na ndị na - egbochi ACE, dịka ọmụmaatụ, Captopril, Enalapril, bụ nke a mebiri ọrụ nke urinary sistem na imebi nguzo mmiri-electrolyte,
• ojiji nke Lozap yana ngwakọta ọgwụ mgbochi tetracyclic nwere ike ime ka mbelata ọbara mgbali elu na-adịgide.
• mgbe ị na-eji Lozap na glucocorticosteroids (Prednisolone, Betamethasone), enwere ụkọ elektrolytes: calcium, sodium, potassium,
• site na iji njikọ aka nke Lozap na adrenaline, a ga-achọpụta mbelata nke ihe nke abụọ ga-arụ,
• n'otu oge iji Lozap nwere ọgwụ antiarrhythmic (Disopyramide, Quinidine), antipsychotics (Droperidol, Thiapride, Pimozide), yana Vincamycin, Erythromycin, Cisapride, Terfenadine jupụtara na mmepe nke arrhythmia,
• ewere Lozap na angiotensin n'ịtụgharị inzyitor enzyme inhibitor na mmepe nke mmetụta dị njọ, ọkachasị akwara ozi, ike gwụ.

Lozap bụ ihe dị oke mma nke na - egbochi ọgwụ ọbara, nke kachasị na mgbasa akwara, na - ebelata oke ibu, ọ bụkwa onye na - abụghị peptide ngọngọ nke ndị na - anabata AT2 na - enwe ọbara mgbali elu, ntọhapụ nke aldosterone, renin, na vasopressin; ọ bụ naanị ọkachamara nwere ike ịde ya, na-elebara ihe niile anya. mmetụta na mmekọrịta n'etiti ọgwụ ndị ọzọ edepụtara.

Ọgwụ Lozap na Lozap Plus: analogues, ọnụahịa na nyocha

Ajụjụ a na-ajụkarị bụ: “Olee nke ka mma - Lozap ka ọ bụ Lorista?”. N'ezie, ọgwụ ndị a nwere otu arụ ọrụ ha na - arụ ọrụ - potassium losartan. Ejiri Lorista tinyekwara Lozap maka ndị mmadụ na-arịa ụdị ọrịa dị ka nkụchi obi na-adịghị ala ala, ọbara mgbali elu. Njirimara na mmetụta nke ọgwụ ndị ọ fọrọ nke nta ka ha yie.

Isi ihe dị iche bụ ụgwọ dị ala nke Lorista, nke bụ uru bụ isi nke ọgwụ a. Ọnụ ego nke Lozap Nke 30 bụ 300 rubles, na Lorista - 150 rubles. Were analog dị ọnụ ala karịa na inye ikikere nke dọkịta.

Kedu ihe dị iche na Lozap na Lozap Plus?

Ọ bụrụ n’ịchọrọ iji usoro a were usoro ọgwụgwọ, ajụjụ a na-ebilite bụ, kedu ọgwụ kacha mma Lozap ma ọ bụ Lozap Plus.

Isi ihe dị iche bụ na a jikọtara ọgwụ nke abụọ - ihe ndị na-arụ ọrụ bụ potassium losartan na hydrochlorothiazide, nke bụ diuretic ma nwee mmetụta diuretic.

Ọgwụ abụọ ahụ bụ angiotensin receptor blockers. Ha na - enyere aka igbochi oghere arteries. Nsonye nke losartan n'ime ha bụ otu, mana ọgwụ Lozap Plus dị iche na Lozap na arụmọrụ ka ukwuu, ebe ọ nwere ihe abụọ na-arụ ọrụ na-agakọ ibe ha.

Ihe ozo di iche n'etiti Lozap Plus na Lozap bu na emeputara nke mbu n’otu usoro onunu ogwu - 50 mg nke losartan + 12.5 hydrochlorothiazide.

Enwere ọtụtụ analogues nke ọgwụ a. Ihe ndị kachasị ewu ewu bụ: Nortian, Irsar, Hyposart, Valz, Atakand, Naviten, Aprovel, Diovan, Kandekor, Mikardis, Valsartan.

Na mgbakwunye na nke ọgwụ a, enwerekwa okwu okwu ọgwụ a na - agbagha - ha nwere ihe ndị yiri ya: Brozaar, Vazotens, Losartan, Losakar, Lotor, Renikard, Lorista.

Ọzọkwa, dọkịta ahụ nwere ike ịkọ ọgwụ dabere na ọgwụ guanfacin.

Ọnụ ego Lozap 12.5 Nke 30 bụ 200 rubles, 12.5 Nke 90 bụ 550 rubles, 50 mg Nke 30 bụ 270 rubles, 50 mg Nke 60 bụ 470 rubles, 50 mg Nke 90 bụ 670 rubles, 100 mg Nke 30 bụ 320 rubles, 100 mg Nke 60 - 560 rubles, 100 mg Nke 90 - 750 rubles.

Ọnụ ego nke Lozap gbakwunyere 12.5 mg Nke 30 bụ 350 rubles, na Nke 90 bụ 800 rubles.

Valery, onye dị afọ 54, lara ezumike nká

“E kenyere m prima Lozapa. Were ogologo oge, mmetụta dị ukwuu. Ihe mgbu n’obi belatara, nrụgide ahụ awụlighị elu, ọ kwụghachị, ahụike amazikwara ahụ ike. M na-agwa ya onye ọ bụla, ọgwụ na-arụ ọrụ nke ukwuu. ”

Diana, onye gbara afọ 52, na-esi nri

“Mgbe o mere agadi, nsogbu bịara, ọkachasị, arụ nke obi. Ọtụtụ mgbe ọ na-arịa ọbara mgbali elu. Agaghị m dọkịta, m ga-a thatụ ọgwụ ahụ, ahụkwa ọzọ. Nwa m nwanyị siri ọnwụ na-aga ụlọ ọgwụ. Dọkịta nyere ya iwu Lozap. O were ogologo oge, mana o ruru ya. N'ime naanị izu abụọ, ọ malitere nwe ahụ mma. Nrụgide ahụ bụ ihe dịkarịsịrị mma na ọ dịghị awụli elu. "

Vladimir, onye gbara afọ 60, onye okenye

Enwere m obi nkụda mmụọ. Anọwo m na-ewere Lozap ogologo oge. Pgwọ ọgwụ ndị a dị mma, mana mgbe ụfọdụ oke mmiri na-emeri nke na ị nweghị ike ị getụ mmanya n'ụzọ ọ bụla. Na mgbakwunye, ụkwara na-enweghị uche na-apụta mgbe ụfọdụ. Mana ọ nweghị ihe ọbụla ma e jiri ya tụnyere ọgwụ ịba uru. Anabatara m ya na ndị ọzọ, na ịkwụwa aka ọtọ, m ka mma. "

Pharmacodynamics na pharmacokinetics

Lozap bụ ọgwụ ọgwụ hypotensive, onye na - emegide ya nke nnabata angiotensin II. Ọ na - ebelata oke nguzogide ọgbụgba, na - ebelata ọkwa nke adrenaline na aldosterone n’ime ọbara. N'okpuru mmetụta ya, nrụgide na mgbasa nke akwara na-ebelata, mmetụta diuretic na-amalite, ma ibulata mbelata. Lozap na - egbochi usoro hypertrophic nke myocardium, na - enyere aka ịbawanye nnabata mmega ahụ na ndị nwere nkụda obi.

Mmetụta kachasị hypotensive mgbe otu ọgwụ ọgwụ ahụ mechara awa 6, emesia ọ jiri nwayọ belata oge awa 24. Site na usoro ọgwụgwọ, utịp kachasị (iwetulata mgbali ọbara) na-apụta izu atọ ruo izu isii ebidochara ọgwụgwọ.

O kwesiri iburu n'uche na n'ime ndi mmadu nwere cirrhosis, ịta nke ọrụ ubara na-abawanye nke ọma (losartan) na plasma ọbara. Ya mere, a na-ekenye ndị ọrịa dị otú ahụ ọgwụgwọ pụrụ iche, belata.

Ọpụpụ site na akwara afọ na-apụta ngwa ngwa. Usoro ndu nke ogwu a di ihe dika 33%. Mgbe nchịkwa ọnụ gachara, ịta ọkwa Plasma kacha elu dị otu elekere. A na-ahụta mkpanye kachasị na ọgwụ metabolite mgbe awa 3-4 gachara. Ndụ ọkara nke losartan bụ awa 2, metabolite nọ n'ọrụ bụ awa 9. 35% nke ọgwụ a gbapụrụ na mmamịrị, ihe dị ka 60% site na eriri afọ.

Ngwakọta na ụdị ntọhapụ

Lozap dị na mbadamba mbadamba (usoro nke 12.5 na 50 mg). Ihe na-arụ ọrụ bụ losartan. Mbadamba ụrọ Lozap dịka ntuziaka ahụ nwere ihe ndị ọzọ inye aka: microcrystalline cellulose, mannitol, colloidal silicon dioxide, crospovidone, talc, magnesium stearate, hypromellose, macrogol, titanium dioxide.

Mbadamba Lozap bụ oval, biconvex, nke nwere ihe nkiri. A na-eme ọgwụ ahụ na blister nke mbadamba iri. N'ime ngwugwu kaadiboodu enwere ike blister 3, 6 ma ọ bụ 9 nwere ntuziaka.

Jiri n'oge ime na lactation

Emebeghị nnyocha Clinical banyere ojiji Lozap n'oge afọ ime. Okwesiri iburu n'uche na amaara mara na ọgwụ na-arụ ọrụ na sistemụ angiotensin-aldosterol nwere mmetụta teratogenic (na-akpata arụrụala na ọbụna ọnwụ nwa ebu n'afọ). Ọ bụrụ na ime mere n'etiti iji Lozap, mgbe ahụ, ekwesịrị ịkagbu ya ozugbo. N'oge a na-enye nwa ara, anaghị akwado ọgwụ maka iji ya.

Mmetụta akụkụ

Dabere na nyocha, Lozap adịkarịghị akpata nsonaazụ. Ọ bụrụ na nsonaazụ n'akụkụ, mgbe ahụ ọnọdụ a na-adịkarị nwayọ ma wepụ ọgwụ ịchọrọ. Ihe kachasị emetụta Lozap na ọgwụgwọ ọbara mgbali elu bụ ọgbụgba (4.1%). Achọpụtara orthostatic mmetụta nke Lozap dịka nyocha si bụrụ ihe na-erughị 1% nke ndị ọrịa.

Nsonaazụ ndị ọzọ nke Lozap ihe fọrọ nke nta adịghị iche na nsonaazụ ndị ọzọ mgbe ị na-a placeụ ọgwụ ("ogbi"), ya mere mmekọrịta ha na iji ọgwụ a bụ ihe ịrụ ụka. Nsonaazụ gụnyere asthenia, ike ọgwụgwụ, mgbu obi, ọria, akụkụ ahụ, afọ ọsịsa, mgbu afọ, ọgbụgbọ, azụ na / ma ọ bụ mgbu ụkwụ, ihe mgbu akwara nke nwa ehi, isi ọwụwa, ehighị ụra, ụkwara, mkpọchi imi. .

Mmekọrịta na ọgwụ ndị ọzọ

Dabere na ntuziaka ahụ, enwere ike ijikọ Lozap na ọgwụ ndị ọzọ na - egbochi ya, ọ na - eme ka mmekọrịta nke ọmịiko na ndị na - achọpụta beta.

Site na iji Lozap na diuretics jikọtara ọnụ, achọpụtara mmụba nke ihe ọgwụ abụọ ahụ kwuru.

Site na nchịkwa nke oge a na digoxin, hydrochlorothiazide, warfarin, cimetidine, phenobarbital, erythromycin na ketoconazole, enweghị ọgwụ mmekọrịta. Dika ntuleta, Lozap na ogwu ndia na aru nke oma, n’enweghi oria obula.

Ojiji Lozap tinyere potassium-sparing diuretics (spironolactone, amiloride, triamteren) na-abawanye ihe ize ndụ nke hyperkalemia.

Lozap: ọnụ ahịa na ụlọ ahịa ọgwụ dị n'ịntanetị

Lozap 12.5 mg mbadamba ihe nkiri 30 pcs.

LOZAP 12.5mg 30 PC. mbadamba ihe mkpuchi

LOZAP AM 5mg + 50mg 30 PC. mbadamba ihe mkpuchi

LOZAP 100mg 30 PC. mbadamba ihe mkpuchi

LOZAP 100mg 60 PC. mbadamba ihe mkpuchi

Lozap 12.5 mg mbadamba ihe eji eme ihe nkiri 90 pcs.

LOZAP 50mg 30 PC. mbadamba ihe mkpuchi

Mbadamba mbadamba 50/30 nke pirams.

Mbadamba mbadamba ụrọ nke 100 mg 30 pcs.

Lozap tab. p.p.o. 50mg n30

LOZAP AM 5mg + 100mg 30 PC. mbadamba ihe mkpuchi

Lozap tab. p.p.o. 100mg n30

Lozap tbl p / pl / o 50mg Nke 30

Lozap 50 mg 30 mbadamba

LOZAP PLUS 50mg + 12.5mg 30 PC. mbadamba ihe mkpuchi

Lozap Plus 50 mg + 12.5 mg mbadamba ihe nkiri 30 pcs.

Nyocha Lozap Plus

Lozap gbakwunyere taabụ. p.p.o. 50mg + 12.5mg n30

Lozap 100 mg 30 mbadamba

Lozap AM 5 mg + 100 mg mbadamba ihe nkiri 30 pcs.

Lozap tbl p / pl / o 100mg Nke 30

Lozap AM 5 mg + 50 mg mbadamba ihe nkiri 30 pcs.

LOZAP 12.5mg 90 PC. mbadamba ihe mkpuchi

Lozap gbakwunyere 50 mg gbakwunyere 12.5 mg 30 mbadamba

Lozap am tab. n / onye a dọtara n’agha. 5 mg + 50 mg Nke 30

Lozapas gbakwunye tbl p / pl / o 50mg + 12.5mg Nke 30

Mbadamba mbadamba 50-piragiri 60 pcs.

LOZAP 50mg 60 PC. mbadamba ihe mkpuchi

Lozap tab. p.p.o. 50mg n60

Mbadamba mbadamba vidiyo 90 mg 90 pcs.

Lozap am 5 mg gbakwunyere 100 mg 30 mbadamba

Mbadamba mbadamba ụrọ nke 100 mg fim 60 pcs.

Lozap am 5 mg gbakwunyere 50 mg 30 mbadamba

Lozap am tab. n / onye a dọtara n’agha. 5 mg + 100 mg Nke 30

Lozap AM tbl p / pl / o 5mg + 100mg Nke 30

Lozap Plus 50 mg + 12.5 mg mbadamba ihe eji eme ihe nkiri 60 pcs.

LOZAP PLUS 50mg + 12.5mg 60 PC. mbadamba ihe mkpuchi

Lozap gbakwunyere taabụ. p.p.o. 50mg + 12.5mg n60

Lozap AM tbl p / pl / o 5mg + 50mg Nke 30

LOZAP 100mg 90 PC. mbadamba ihe mkpuchi

Lozap 50 mg mbadamba ihe nkiri 90 pcs.

Lozap Plus 50 mg + 12.5 mg mbadamba ihe nkiri 90 pcs.

Nyocha Lozap Plus

Lozap gbakwunyere 50 mg gbakwunye mbadamba 12.5 mg 60

LOZAP 50mg 90 PC. mbadamba ihe mkpuchi

Lozap tbl p / pl / o 100mg Nke 90 *

Lozap gbakwunyere tbl p / pl / o 50mg + 12.5mg Nke 60

Lozap gbakwunyere taabụ. p.p.o. 50mg + 12.5mg n90

LOZAP PLUS 50mg + 12.5mg 90 PC. mbadamba ihe mkpuchi

Lozapa gbakwunye tbl p / pl / o 50mg + 12.5mg Nke 90

A na - emejupụta ozi gbasara ọgwụ ahụ, enyere ya aka ka ọ nweta ihe ọ bụla, ọ naghị edochi ntuziaka gọọmentị. Medication medicationụ onwe gị ọgwụ dị ize ndụ nye ahụ ike!

Imeju bụ akwara kacha anyị n’ahụ. Ogo ya di 1.5 n'arọ.

Dabere na ọmụmụ, ụmụ nwanyị ndị na-a severalụ ọtụtụ iko biya ma ọ bụ mmanya n'izu, ha nwere ohere dị ukwuu nke ịrịa ọrịa cancer ara.

E mepụtara akpa vibrator na narị afọ nke iri na itolu. Ọ rụrụ ọrụ na uzuoku ma na-bu n'obi na-agwọ ọrịa nwanyi.

Afọ mmadụ na-arụ ọrụ dị mma site na iji ihe ndị si mba ọzọ na-enweghị ọgwụ. A maara ihe ọ juiceụastụ na-egbu egbu na-agbaze ọbụna mkpụrụ ego.

Ndi Sayensi si Mahadum Oxford mere otutu ihe omumu, mgbe ha biara na nkwubi okwu banyere na akwukwo nri nwere ike ibutere ụbara mmadu agha, ebe ọ na-ebute mbelata nke oke ya. Yabụ, ndị ọkà mmụta sayensị na-atụ aro ịhapụ iwepụ azụ na anụ na nri ha.

Ndị ọkà mmụta sayensị America mere nyocha na ụmụ oke wee kwubie na mmiri mmiri mmiri na-egbochi mmepe nke atherosclerosis nke arịa ọbara. Otu ìgwè na -a mụ mmiri dị ọcha, nke abụọ abụrụ mmiri ọ aụ juiceụ. N'ihi nke a, arịa nke ndị otu nke abụọ enwere nnukwu palesterol.

Iji kwuo ọbụna okwu kachasị mkpụmkpụ ma dị mfe, anyị na-eji akwara iri abụọ na asaa.

O buru na inyinya inyinya, ino na ntukwasiri gi karie ka inwere n’agha. Naanị anwala igosipụta nkwupụta a.

N'ime pasent 5 nke ndị ọrịa, Clomipramine antidepressant na-akpata mkpali.

Ndị dọkịta ezé apụtawo n'oge na-adịbeghị anya. Laa azụ na narị afọ nke 19, ọ bụ ọrụ dịịrị onye na-edozi isi nkịtị iji wepụ ezé na-arịa ọrịa.

N'oge ị na-arụ ọrụ, ụbụrụ anyị na-etinye oke nha anya ya na bọlbụ 10-watt. Yabụ na onyinyo nke oriọna dị n’elu isi gị n’oge ngosipụta nke echiche na-adọrọ mmasị adịghị anya n’eziokwu.

Onye na-a antụ ọgwụ mgbochi n’oge ikpe ga-enwetakwa ịda mbà n’obi ọzọ. Ọ bụrụ na mmadụ anagide nkụda mmụọ na aka ya, ọ nwere ohere ọ bụla ichefu ọnọdụ a ruo mgbe ebighi ebi.

Ọtụtụ nde nje na-amụ, na-ebi ma na-anwụ na anyị gootu. Enwere ike ịhụ ha naanị na nnukwu ịdị elu, ma ọ bụrụ na ha gbakọtara ọnụ, ha ga-adaba na iko kọfị mgbe niile.

Ibu ahụ ụbụrụ mmadụ dị ihe dịka 2% nke mkpokọta ahụ, mana ọ na - eri ihe dị ka 20% nke oxygen na - abanye n'ọbara. Eziokwu a na-eme ka ụbụrụ mmadụ nwee ike ịkwụsi ike maka mmebi nke enweghị oxygen.

Nwa nwoke onye Australia dị afọ 74, James Harrison ghọrọ onye na-enye ọbara n'ihe dị ka 1,000 ugboro. O nwere ụdị ọbara dị ụkọ, ọgwụ mgbochi nke enyere ụmụ amụrụ ọhụrụ aka na-arịa oke anaemia. N'ihi ya, onye Australia chebere ihe ruru ụmụaka nde abụọ.

Oge izizi nke okooko osisi na-abịa na njedebe, mana ahịhịa ga-anọchi ahịhịa site na mbido June, nke ga-akpaghasị ndị na-arịa ya.

N'oge ime na lactation

Emela Lozap n'oge ime. N'oge ọgwụgwọ n'ime oge nke abụọ na nke atọ yana ọgwụ ndị na-emetụta usoro renin-angiotensin, ntụpọ na mmepe nke nwa ebu n'afọ na ọbụna ọnwụ nwere ike ime. Ozugbo ime dị, nwa ahụ kwesịrị ịkwụsị ọgwụ ozugbo.

Ọ bụrụ na a ga-ewere Lozap n'oge a na-enye ya ara, a ga-akwụsị inye ya ara ozugbo.

Nyocha na Lozap Plus na Lozap na-atụ aro na n'ọtụtụ oge, ọgwụ ọgwụ belata nke ọma ọbara mgbalima nwee mmetụta dị mma na ahụike nke ndị mmadụ nwere ọrịa nke akwara obi. Ndị ọrịa na-aga nnọkọ ahụ pụrụ iche ịhapụ nzaghachi na Lozap 50 mg mara na ụkwara, akpịrị ịkpọ nkụ, na nkwarụ ntị bụ mgbe ụfọdụ ka a na-ahụta ya. Mana n’ozuzu, nyocha ndị ọrịa banyere ọgwụ a dị mma. N'otu oge, nyocha ndị dọkịta na-egosi na ọgwụ nwere ike ọ gaghị adabara mmadụ niile na-arịa ọbara mgbali elu. Ya mere, na mbu, ekwesịrị ịdaba n'okpuru nlekọta nke ọkachamara.

Ọnụahịa, ebe ịzụta

Ọnụahịa nke Lozap na ụlọ ahịa ọgwụ dịgasị na 230 rubles. (Lozap 12.5 mg, 30 PC.) Ruo 760 rubles (Lozap 100 mg, 90 PC.). Ọnụahịa nke mbadamba 50 mg mg na Moscow na obodo ndị ọzọ dị ihe dị ka 270-300 rubles. Mgbe ụfọdụ ị nwere ike ịzụta ọgwụ na ọnụ ala dị ala na-enye nkwado. Ọnụahịa nke Lozap Plus 50 mg (mbadamba 90) - site na 720 rubles.