Kedu ihe na-enyere Siofor aka? Ntuziaka, ọnụahịa, nyocha na analogues

Siofor bụ ọgwụ sitere na ndị otu biguanide. Ngwakọta kachasị arụ ọrụ bụ metformin, nke ejirila na-agwọ ọrịa shuga kemgbe ọtụtụ afọ.

N’adịghị ka ọgwụ antidiabet ndị ọzọ, ọgwụ a na -ebelata mmepụta glucose site n’akwara mkpụrụ ndụ, na-egbochi nnabata ya n’akụkụ akụkụ nke eriri afọ, na-eme ka uru akwara dịkwuo glucose ike, ma na -ebelata ọnụego insulin na-adị n’ahụ.

Isi mmetụta nke ị theụ ọgwụ:

• iwetulata ma mee ka ogo nke gemocolobin glycosylated na glucose ọbara dị,
• anụ ahụ na-aba ụba site na anụ ahụ,
• ubara nnabata shuga di n’ọbara.

• na-ebelata lipoproteins dị ala na nke dị ala
• nwere ihe antioxidant na nchebe na sel membran,
• normalizes ahu nwere oke ibu.

A na-eji ọgwụ a agwọ ọrịa shuga 2.

Releasedị nke ịhapụ ọgwụ

Mkpụrụ ọgwụ ahụ nwere ụdị ntọhapụ dị iche iche, ha nile edoziri iche, nke na-eme ọgwụ ahụ ka ọ dịrị gị mfe ịnwe n ’ụlọ.

• Siofor 500 - mbadamba ọcha, elongated, coated, nke akara n’ime blisters pụrụ iche nke mkpụrụ iri na ise, ngwungwu kaadiboodu ọ bụla nwere site na blisters abụọ ruo asatọ,
• Siofor 850 - mbadamba ọcha, oblong, nwekwara mkpuchi, juru eju na blisters nke iberibe iri na ise, na ngwungwu kaadiboodu ọ bụla site na blisters abụọ ruo asatọ,
• Siofor 1000 - mbadamba ọcha na obere mkpirisi n’elu, nwere shei, a na-etinyekwa ya na blisters nke mkpụrụ iri na ise, n’otu ngwugwu site na blisters abụọ ruo asatọ na mbadamba.

Ihe ngbanwe

Nkọwa nke ọgwụ ọ bụla gụnyere isi nke na contraindications. Enweghị nlebara anya dị mma na akụkụ nke ntụziaka a, enwere nnukwu ihe ọghọm nke nsogbu dị iche iche.

Ihe mgbochi iji Siofor dika onye nnochi anya ogwu:

• hymenke si ọgwụ nke ọgwụ,
• ụdị shuga mellitus, ọgwụ insulin,
• Coma shuga mgbe hyperglycemia,
• akpọ ketoacids,
• Ọnọdụ ujo: obi ọgụ, ụjọ na - egbu egbu na obi ụfụ,
• nsogbu na mmiri-electrolyte nguzozi,
• ike ọgwụgwụ na anorexia,
• nnukwu mbibi mebiri ihe karịrị 40% nke ahụ,
• ọbara ọgbụgba karịrị otu lita na ọkara.
• ịwa ahụ n'okpuru akwara ma ọ bụ azụ azụ,
• ọrịa na-efe efe nke sisitemu akwara na usoro bronchopulmonary,
• eriri afọ ime mmụọ nke eke ma ọ bụ ahụ mkpọnwụ,
• eriri afọ,
• nsogbu na malaba,
• Ọrịa endocrine system: thyrotoxicosis, autoimmune thyroiditis, ọrịa ọla, gestational diabetes mellitus,
• ọrịa febrile
• ị alcoholụ mmanya na-egbu ogologo oge.
• ihe riri ahu
• tụụrụ ime n'afọ atọ niile,
• inye ara
• otu gbara afọ ruru afọ iri yana ndị gbara afọ iri isii na ise.
• akpụ ọnya nke ọnya afọ na ụmị ọkpụkpụ nke malignant na benign etiology.

Ọgwụ a dabere ma a ga-eji ọgwụ ahụ yana ndị ọgwụ antidiabet ọzọ. A na - ahọrọ ọgwụ kachasị mma site na endocrinologist mgbe a nyochachara ya. Ọgwụ nwere ike ịnwe 0,5, 0.85 na 1 gram nke ihe bụ isi.

Siofor ọgwụ naanị

Ha na ebido were ọgwụ were ọgwụ 0,5 otu ugboro ma ọ bụ ugboro abụọ n’ụbọchị ma ọ bụ site na gram 0.85 otu ugboro n’ụbọchị. Izu abụọ mgbe mmalite nke nchịkwa, na enweghị mmetụta na-adịghị mma, mụbaa usoro iji nwayọọ nwayọọ ruo 1.5-2 gram. Ọ bụrụ n’iji nwayọ na-abawanye ụba ọgwụ, mgbe ahụ nsonaazụ ga-ebido na nke kacha nta.

Ngwakọta ọgwụ

Ọtụtụ mgbe, a na-ejikọ siofor na insulin na ọgwụgwọ shuga. N'otu oge ahụ, ha na-amalite ị drinkụ mbadamba ihe ọ aụ ofụ nke 0,5 gram, kwa izu na-abawanye site na ọkara gram ọzọ ruo mgbe ọ ruru nkezi kwa ụbọchị (3-4 grams). A na-ekpebi ọnụọgụ insulin insulin site na ịhazi shuga ọbara.

Ntụziaka maka ojiji

A na-ewere Siofor, onye nkuzi ya maka nsogbu adịghị akpata otu nsogbu, otu ugboro ma ọ bụ ugboro abụọ n'ụbọchị (dabere na usoro onunu ogwu nke onye okacha idebere). Ọ na-atụ aro iburu mbadamba nkume ahụ tupu isi nri, were iko mmiri dị ọcha sachaa ha. Ọ bụ ihe anabataghị ị drinkụ mbadamba mmanya na mmanya, mkpụrụ osisi gbara ụka ma ọ bụ ihe ọ vegetableụ vegetableụ mmiri, yana ngwaahịa mmiri ara ehi, n'ihi na nke a ga-emetụta Njirimara ọgwụgwọ nke ihe ahụ.

Ntụziaka pụrụ iche

Ọ bụrụ na edepụtara ọgwụ ahụ yana ngwakọta nke sulfonylurea ma ọ bụ insulin, a chọrọ iburu n'uche ọkwa nke glucose dị n'ọbara n'oge dị iche iche n'ụbọchị. Ọ dịkwa mkpa iji lee nyocha maka haemoglobin glycosylated.

Mgbe ị theụsịrị ọgwụ ahụ, a na-atụ aro ka ị nweta nyocha urinalysis na nyocha nke biochemical nke mmamịrị na ọbara kwa ọnwa isii, yana ikpebi ọnụego nhicha ahụ. Nyocha ndị a na-enye gị ohere ikpebi ọnọdụ akụrụ na nsonaazụ nke ọgwụ na sistem.

Ọ bụrụ na onye ọrịa ahụ nwere ọrịa ngụgụ, ọrịa imeju, ma ọ bụ ọrịa na-efe efe yana ọrịa nje, ị kwesịrị ịgwa dọkịta gị ozugbo banyere nke a wee gụta banyere usoro ọgwụgwọ ọzọ.

Ọ bụrụ na a ga-enyocha onye ọrịa ahụ na ntinye nke ọdịiche redio ma ọ bụ ịwa ahụ, a ga-akagbu ọgwụ ahụ ụbọchị abụọ tupu usoro ahụ.

Breastụ ara araparaghị n’ị theụ ọgwụ. Nyocha nke ndị ọkachamara gosipụtara na ọgwụ ahụ dị na mmiri ara ara. Mgbe ị na-eme atụmatụ ịtụrụ ime n’ime ọnwa ole na ole ị takingụchara ọgwụ ahụ, ị ​​ga-eme ka dọkịta ndị na - eleta anya mara banyere nke a ma mee onye ọzọ.

Mmekọrịta nke ọgwụ ya na ọgwụ ọgwụ ndị ọzọ

Mgbe achoputara otutu ogwu na aru n’otu oge, nke a gha agbanwe oke ha. Ọrịa shuga na-esiri ike ịchịkwa na-eduga n'iji ọtụtụ ndị ọrịa hypoglycemic otu oge, nke nwere ike ibute ụfọdụ mmetụta na-adịghị mma.

Mmetụta nke mmekọrịta nke Siofor na ọgwụ ọgwụ ndị ọzọ:

• loop, thiazide na potassium na-eme ka ọnụọgụ belata mmetụta belata shuga,
• glucocorticosteroids, mgbochi homonụ, ọgwụ nke homonụ nwoke na nwanyị (nke nwere testosterone, estrogens) na-emetụta oke ọrụ hypoglycemic,
• nifedipine, nicardipine na - eme ka nnabata nke ọgwụ dị n’elu eriri afọ dị n’elu,
• insulin na insulin dika ihe ndi ozo, nhazi nke sulfonylurea na –eme ka isi ihe ogwu buru ihe ma nwee ike ibute oria
• antidepressants, angiotensin-na-agbanwe enzyme inhibitors na ụfọdụ ọgwụ nje na-abawanye arụmọrụ nke siofor,
• mgbe ị na-ewere cimetidine, a na - akụghasị ọgwụ nke ahụ site na ahụ, nke nwere ike ibute ketoacidosis,
• ị alcoholụ mmanya na-abawanye n'ihe ize ndụ nke steeti ketoacidotic ọtụtụ oge,
• iodine nwere ihe ndị na-enye rediopaque ọgwụ na siofor nwere ike ibute mmeghachi omume nhụjuanya na edema nke Quincke na mmepe na-esote ukwara ikuku.

Nsonaazụ

Siofor 500 nwere ike ibute ụfọdụ nsonaazụ, nke ụkpụrụ bụ njiri mara ọgwụ ọ bụla. Ọtụtụ n'ime ha na-ebilite n'ihi njirimara nke mmekọrịta mmadụ na ibe ya nke ihe ndị ọzọ yana ọgwụ ndị ọzọ na-anabata ọgwụ.

Nsonaazụ ndị ọzọ na-esokarị site na ị Sụ Siofor:

• dyspepsia na ngosipụta niile: mgbaàmà nke obi mgbawa na obi ilu, na-emegharị ahụ,
• mmegharị nke gag reflex, ọgbụgba,
• afọ ọsịsa na afọ ntachi,
• mkpọchi gas na mpaghara eriri afọ,
• itinye aka na afọ,
• inwe afọ ojuju mgbe ị gachara obere nri,
• uto nke ilu
• mbelata nke ukwuu na glucose ọbara, na-eduga na ọnọdụ hypoglycemic,
• syncope na syncope
• migraine na migraine vertigo,
• nchara, uhere,
• ifelata
• ịda mbà n'obi ruo ogologo oge, na-esote omume ike,
• hematopoiesis: megaloblastic anaemia,
• omume mgbanwe
• na-ama jijiji nke nsọtụ elu,
• ura ma ọ bụ ehighị ụra nke ukwuu,
• akpụkpọ ahụ,
• anụ ahụ
• ihe akpukpọ aru na akpukpọ aru-ya,
• allergies na mmeghachi omume nfụkasị ahụ: edere Quincke, ujo anafilactic,
• mmepe nke nnukwu gbasara akụrụ odida,
• mmepe nke mmebi imeju na-adịghị ala ala.

Ogwu ahu di n’etiti onu ahia. Iwu ịnye ọnụahịa n'obodo dị iche iche nke ụwa dịgasị obere. Dị ka ọ dị n’obodo ukwu na n’obodo a, ọnụahịa ahụ ga-adabere n’ihe ọ̀ka dọkịta nyere gị. Ndi iche di iche n’ihe Siofor 500 na Siofor 1000 di ezigbo nkpa.

Nkezi ọnụ ahịa n'obodo dị gburugburu ụwa:

1. Na mpaghara Moscow na mpaghara Russia, enwere ike ịchọta ọgwụ ahụ maka ọnụahịa nke 340 ruo 850 rubles.
2. Na St. Petersburg, ọnụ ahịa ọgwụ ga-abụ site na 350 ruo 850 rubles.
3. N'ime ụlọ ahịa ọgwụ n'obodo Chelyabinsk siofor na-akwụ ụgwọ site na 265 ruo 340 rubles.
4. Ndị ahịa ọgwụ Novosibirsk rere ọgwụ ahụ na ọnụahịa nke 215 ruo 800 rubles.
5. Na Lipetsk na mpaghara Lipetsk, mmadụ nwere ike inye site na 212 ruo 840 rubles maka ọgwụ.
6. Ndị na-ere ọgwụ na Rostov-on-Don na-ekpughere ọgwụ ọgwụ na ọnụahịa site na 347 rubles ruo 860.
7. Na Vladivostok, ịnwere ike ịzụta ọgwụ ndị a na ọnụahịa nke 234 ruo 836 rubles.

Siofor, dịka ọgwụ ọ bụla, nwere ọgwụ analogues nke ya. Ọtụtụ n'ime ha dịgasị iche naanị na mba na-emepụta ihe. Formsfọdụ ọgwụ nwere obere mgbanwe na ha mejupụtara, nke a na-eme ka ha nwekwuo ego maka ụfọdụ mmadụ.

Isi analogues nke ọgwụ:

1. Glucophage bụ ọgwụ French mepụtara nke nwere ụfọdụ ọdịiche dị na ihe enyemaka nke ọgwụ ahụ. Ọnụahịa dị na ụlọ ahịa ọgwụ sitere na 122 ruo 322 rubles.
2. Bagomet, n'adịghị ka ọgwụ ndị ọzọ, nwere ụfọdụ ihe mgbochi afọ iji ya eme ihe: maka ndị gaferela afọ iri isii ka ejiri nlezianya dezie ya. Akụkụ ọnụahịa sitere na 110 ruo 340 rubles.
3. Glycon bụ ọgwụ ndị Canada. Ọzọkwa, dị ka analogues ndị ọzọ, ọ nwere metformin, mana enwere ya n'ụdị mbadamba ihe eji achịcha. N'ime ụlọ ahịa ọgwụ ị nwere ike ịchọta ọnụahịa mara mma nke 219 rubles.
4. Glyminfor bụ ọgwụ nke ụlọ ọrụ na-emepụta ọgwụ na India. Na-akpata nsonaazụ ndị ọzọ metụtara ọrụ eriri afọ. Nyocha banyere ọgwụ a na-agwakọta. Ọnụahịa a tụrụ aro na ụlọ ahịa ọgwụ bụ 200 rubles.
5. Pliva Mpempe - nwere obere mgbanwe na ihe ndị mejupụtara ozu. Ọnụahịa ikpeazụ na ụlọ ahịa ọgwụ bụ 250 rubles.
6. Metfogamma bụ ọgwụ German. Iji ogologo oge, ọ nwere ike ibute obere vitamin. Erere ke ahịa ọgwụ na ọnụahịa nke 180 ruo 660 rubles.
7. Metformin dị ogologo - n'adịghị ka metformin mgbe niile, na-enwe mmetụta na-adịgide adịgide. Ọnụahịa ahụ sitere na 135 ruo 262 rubles.

Dodoụbiga ya ókè

Mgbe ị na-a theụ ọgwụ ahụ karịa ọgwụ ndị dọkịta tụrụ aro ya, onye ọrịa ahụ na-amalite lactic acidosis (mgbanwe mgbanwe acid-base na ahụ).

Ihe mgbaàmà nke lactic acidosis:

• ọgbụgbọ
• vomiting
• afọ ọsịsa
• mgbu afọ
• ịba ụba gas,
• spasmodic muscle mgbu
• mmetụta nke enweghị ikuku.

Ọ ga - ekwe omume mmepe nke hypoglycemia, na - agafe n'ime mmiri ọgwụ hypoglycemic. Ọnọdụ a sokwa nsụhọ, nkụda mmụọ nke mgbanwe ahụ, ọrịa ọgbụgba, ọsụsọ oyi na iku ume.

Ihe enyemaka mbu maka hypoglycemia na lactic acidosis - glucose na -eme ya ọnụ ma na ntinye.

Nwere ike iji obere shuga ma ọ bụ mmanụ a .ụ. Mgbe nke ahụ gasịrị, ekwesịrị ịkpọbara onye ọrịa ahụ n'ụlọ ọgwụ pụrụ iche, ebe ọ ga-anwale hemodialysis iji wepu ihe ahụ na-arụ ọrụ n'ahụ ahụ.

Siofor bụ ọgwụ hypoglycemic dị irè nke nwere ma uru dị ukwuu yana ọtụtụ ọghọm ya. Ọ dị mma icheta na, nke mbụ, Siofor 500 na Siofor 1000 na-enyere aka belata shuga ọbara, na-atụkwasịkwa na nyocha nke ndị na-eji ha dị ka ọgwụ ọjọọ maka oke ibu bụ ihe ekwesighi. Ọgwụ ọkachamara ga-ekwenye ma kwado ya.

Mwepụta wepụtara ya na ihe mebere

A na-enweta Siofor n'ụdị mbadamba nkume ndị nwere ihe nkiri na-acha ọcha.

Ihe nọ n'ọrụ bụ metformin hydrochloride. Olu ya na nkwadebe bụ 500 mg, 850 mg ma ọ bụ 1000 mg, ihe inyeaka: povidone, hypromellose, magnesium stearate, mkpuchi ihe nkiri: macrogol 6000, hypromellose, titanium dioxide.

Ngwongwo ogwu

Siofor, ntuziaka maka iji nke a gosipụtara nke a, na-enye mbelata na ọkwa basal na postprandial. Ọ naghị akpali insulin n'ahụ ya mere ọ dịghị ebute hypoglycemia.

Omume nke metformin (ihe na-arụ ọrụ) bụ ike dabere na usoro ndị a: mbelata mmepụta glucose na imeju n'ihi mgbochi nke gluconeogenesis na glycogenolysis, mmụba nke uru ahụ na insulin na, ya mere, mmụba na glucose na ngụkọta ahụ na iji ya, igbochi glucose absorption na eriri afọ. .

Mbadamba ụrọ Siofor nke 500 mg, 850 mg ma ọ bụ 1000 mg site na mmemme ha na glycogen synthetase na-akpali njikọ intancellular glycogen synthesis. Ike nke mbufe na --eme ka protein na –eme ka protein ghari nile.

Na agbanyeghi mmetụta ọ dị na glucose n'ọbara, ọgwụ nwere mmetụta bara uru na metabolism lipid, na-eduga na mbelata cholesterol, obere cholesterol dị ala na triglycerides.

Ọgwụ "Siofor": ntuziaka maka ojiji (otu esi ewere)

Usoro a ga-agbaso na usoro ọgwụ a, yana oge ọgwụgwọ, ndị dibia bekee na-agbadata n'ọkwa glucose n'ọbara onye ọrịa.

Ndị okenye Na monotherapy, ezigbo ọgwụ mbụ dị ọgwụ bụ 500 mg (1/2 mbadamba Siofor 1000 ma ọ bụ mbadamba 1. Siofor 500) 1-2 ugboro n'ụbọchị ma ọ bụ 850 mg (mbadamba ụrọ 1 Siofor 850) 1 oge ụbọchị.

Daysbọchị 10-15 ka ịmalite ịgwọ ọgwụ gụrụ ọgwụ, ịbawanye ọgwụ ọzọ (nke nwayọ) ga - ekwe omume dabere na ntinye glucose n'ọbara n'ọkara kwa ụbọchị: mbadamba 3-4. 500 mg, mbadamba 2-3. 850 mg ọ bụla, mbadamba abụọ Siofor 1000 mg.

N'okwu a, oke ekwenye ekwenye bụ 3000 mg kwa ụbọchị ekewa n'ime usoro 3.

Maka ndị ọrịa edepụtara ọgwụ oke ọgwụ (2000-3000 mg kwa ụbọchị), enwere ike dochie mbadamba 2. 500 mg kwa 1 mbadamba 1000 mg.

Mgbe ị na-ebufe ndị ọrịa na ọgwụ ọgwụ na ọgwụgwọ ọzọ ọgwụ antidiabetic, ọ dị mkpa ịkwụsị ị theụ ọgwụ ma malite ị tabletsụ mbadamba Siofora na usoro ndị dị n'elu.

Site na iji ọgwụ na insulin jikọtara ọnụ, ọgwụ mbụ bụ 500 mg 1-2 ugboro n'ụbọchị ma ọ bụ 850 mg 1 oge kwa ụbọchị. N’ọdị n’ihu, a na-eji nwayọ were dose ahụ rute elu karịa kwa ụbọchị:

• Mbadamba 3-4 Siofor 500 mg
• Mbadamba mbadamba 2-3 850 mg ọ bụla
• 2 taabụ. 1000 mg nke ọ bụla.

Mee otu oge n'izu. Ọtọ insulin ka edobere onodu glucose n’ime ọbara. Ogo kachasị anabata ga-anabata ya bụ 3000 mg kwa ụbọchị na-ekewa 3 usoro.

Agedmụaka gbara afọ 10 ruo 18.Ọkwa dị larịị nke ọgwụ were jikọta ya na insulin na monotherapy bụ 500 mg yana oge nke 1 oge kwa ụbọchị ma ọ bụ 850 mg 1 oge kwa ụbọchị.

Daysbọchị 10-15 tupu ịmalite ọgwụgwọ, mmụba ọzọ na dose ga-ekwe omume dabere na ịta nke glucose n'ọbara. Oru kachasị kwere maka ụmụaka bụ 2000 mg kwa ụbọchị kewara 2-3 usoro. A na-ekpebi ọ̀gwụ insulin na-eburu n'uche ọ̀tụ̀tụ̀ glucose dị n'ọbara.

Nsonaazụ

The Tụ ọgwụ ahụ nwere ike ibute mmeghachi omume na-adịghị mma:

• akpukpo aru
• megaloblastic anaemia,
• enweghị agụụ
• ọgbụgbọ, vomiting,
• afọ ọsịsa
• flatulence
• mgbu afọ
• ọla uto n'ọnụ
• hypoglycemia (nke megidere usoro usoro onunu ogwu),
• site na ọgwụgwọ ogologo oge, mmepe nke B12 hypovitaminosis (malabsorption) ga-ekwe omume,
• n'ọnọdụ ndị dịpụrụ adịpụ (yana ị ofụ ọgwụ ọdoụ ,ụ ókè, na ọnụnọ ọrịa nke ọgwụ a na - egbochi contraindicated, na ahoụrụma), lactic acidosis nwere ike ịmalite (chọrọ ịkwụsị ọgwụgwọ).

Analogues nke ogwu "Siofor"

Zuru ezu analogues nke ihe na-arụ ọrụ:

1. Sofamet.
2. Mpempe.
3. Metospanin.
4. Metfogamma 1000.
5. NovoFormin.
6. Metfogamma 500.
7. Metphogamma 850.
8. Glyminfor.
9. Methadiene.
10. Metformin.
11. Bagomet.
12. Ọrịa.
13. Glucophage Long.
14. Pliva ike.
15. Langerine.
16. Metformin hydrochloride.
17. Nova Met.
18. Glycon.
19. Gliformin.

Usoro ezumike na ọnụahịa

Ọnụ ego nkezi nke Siofor na Moscow bụ 322 rubles. Na Kiev, ị nwere ike ịzụta mbadamba (500 mg No. 60) maka hryvnias 179, na Kazakhstan - maka 1595 tenge. Na Minsk, ndị na-ere ọgwụ na-enye Siofor 850 Nke 60 maka 9-10 bel. rubles. A na-enweta ya site na ndị ahịa ọgwụ nwere ndenye ọgwụ.

Ihe dị ka nyocha Siofor 1000, 850, 500 nke ndị dọkịta dịcha mma, mana ndị ọkachamara na-ekwusi ike na ịkwesịrị ị byụ ọgwụ ahụ naanị site na ndị ọrịa nwere ọrịa mellitus, ọ bụghị ahụike, na-efunahụ ndị mmadụ. Ọgwụ na - enyere aka iweghachi ọkwa shuga dị ka nke ọma yana, na mgbakwunye, ndị na - arịa ọrịa shuga na - a noticeụ ọgwụ na - achọpụta oke belata.

Na netwọk ị nwere ike ịchọta ọtụtụ nyocha nke ndị tụfuru ibu site n'enyemaka nke ngwa a, ndị na-ekwu na mgbe ị na-ewere ya, agụụ gị ga-agbada. Agbanyeghị, ekwesịrị iburu nsogbu ndị ọzọ ọ bụla n'uche. Enweghị ike ị takeụ ọgwụ n’enweghị ọgwụ dọkịta.