Tricor 145 mg: ntuziaka maka ojiji, analogues na nyocha, ọnụahịa na ụlọ ahịa ọgwụ nke Russia

Tricor bụ ọgwụ hypolipPs nke nwere mmetụta uricosuric na antiplatelet. Na-ebelata cholesterol ọbara n'ogo site na 20-25%, TG ọbara site na 40-45% na uricemia site na 25%. Ihe na-arụ ọrụ bụ Fenofibrate.

Ibelata ọbara triglycerides na (ruo obere obere) cholesterol. Ọ na - enyere aka belata ọdịnaya nke VLDL, LDL (ruo obere obere), bulie ọdịnaya nke anti-atherogenic HDL. Aghọtaghị usoro nke ihe ọ bụla.

Mmetụta dị na ọkwa nke TG metụtara njikọta nke enzyme lipoprotein lipase. N'ụzọ doro anya, fenofibrate na-akụzikwa njikọ nke abụba abụba, na-enye aka na mmụba nke ọnụ ọgụgụ ndị na-anabata LDL na imeju, na-akpaghasị njikọ cholesterol.

N'oge omumu ihe omumu ihe banyere ogwu, achoputara na ojiji nke Tricor belata cholesterol zuru oke site na 20-25% na triglycerides site na 40-55% na mmụba na HDL-C site na 10-30%. N'ime ndị ọrịa nwere hypercholesterolemia, nke na-ebelata ọkwa nke Chs-LDL site na 20-35%, ojiji nke fenofibrate mere ka mbelata n'ọba: mkpokọta Chs / Chs-HDL, Chs-LDL / Chs-HDL na apo B / apo AI, nke bụ ihe nrịbama nke ihe egwu atherogenic.

N'oge ị theụ ọgwụ ahụ, nkwụnye ego cholesterol (akwara na xanthomas) nwere ike belata nke ukwuu ma kwụsịchaa kpamkpam.

Uru ọzọ maka ndị nwere hyperuricemia na dyslipidemia bụ mmetụta uricosuric nke ihe na-arụ ọrụ, nke na-eduga n'ịbelata mkpo acid urukurubụba ihe dịka 25%.

Enwere ihe akaebe nke mbelata agwakọta platelet nke adenosine diphosphate, epinephrine na arachidonic acid.

Ihe ngosi maka ojiji

Kedu ihe na - enyere aka Tricor? Dabere na ntuziaka ndị ahụ, edepụtara ọgwụ ahụ n'okwu ndị a:

Hypercholesterolemia na hypertriglyceridemia dịpụrụ adịpụ ma ọ bụ agwakọta (ụdị dyslipidemia IIa, IIb, III, IV, V) na arụmọrụ nke ụzọ ọgwụgwọ ọgwụ na-adịghị (mmebi ibu, ọrụ na-abawanye ụba), karịsịa na ọnụnọ ihe ndị dị ize ndụ metụtara dyslipidemia - ọbara mgbali akwara na ise siga,
Secondary hyperlipoproteinemia, n'ọnọdụ ebe hyperlipoproteinemia na-adịgide, n'agbanyeghị ọgwụgwọ dị mma nke ọrịa na-akpata (dịka ọmụmaatụ, dyslipidemia na ọrịa shuga mellitus).

Edere ọgwụ a yana nri cholesterol yana akụkụ nke ọgwụgwọ siri ike.

Ntụziaka maka iji Tricor 145 mg, usoro onunu ogwu

Ana ewere mbadamba mkpụrụ ọgwụ Tricor 145 dị ọnụ, n'agbanyeghị nri (dum), ejiri mmiri dị ọcha sachaa. A na-eji ọgwụ eji usoro onunu ogwu nke 160 mg mee nri.

Usoro ọkọlọtọ, dịka ntuziaka maka ojiji a bụ 1 mbadamba ọgwụ Tricor 145 mg 1 kwa ụbọchị. Edere ọgwụ ahụ ogologo oge, mgbe ị na-eri nri.

Dọkịta setịpụrụ dos maka ụmụaka, a na-agbakọọ ogo ahụ dabere na ahụ nwata ahụ - 5 mg / kg kwa ụbọchị.

Ndị ọrịa na-ewere mbadamba 1 nke Fenofibrate 160 mg 1 oge kwa ụbọchị nwere ike gbanwee gaa na-ewere TRICOR 145 mg na-enweghị mgbakwunye dose ọzọ.

Ndị okenye anaghị achọ ndozi ọgwụ. Na ọdịda akụrụngwa, akwara iji ọgwụ ure edenye.

Ntụziaka pụrụ iche

Na enweghị mmetụta na-eju afọ, mgbe ọnwa 3-6 nke ị drugụ ọgwụ ahụ gasịrị, enwere ike ịkọwa mkpụrụ akwụkwọ ndozi ma ọ bụ usoro ọgwụgwọ ọzọ.

A na-atụ aro ka nyochaa ọrụ “transperent hepatic” kwa ọnwa atọ n’ime afọ mbụ nke ọgwụgwọ, nkwụsịtụ nwa oge na ọgwụgwọ ma ọ bụrụ na ọrụ ha na-aba ụba, na mwepu nke ọgwụ ịba ọcha n’anya site n’otu oge ọgwụgwọ.

N'ime ndị nwere hyperlipidemia ndị a na-eji ọgwụ estrogen na-agwọ ma ọ bụ na-a contraụ ọgwụ mgbochi mkpịsị ọnụnụ, gụnyere estrogens, isi ma ọ bụ nke abụọ nke ịmalite hyperlipidemia kwesịrị ikpebisi ike, ebe ọ bụ na ịrị elu nke oke egbugbu ga-ekwe omume n'ihi ị ofụ ọgwụ estrogens.

Nsonaazụ

Ntụziaka ahụ dọrọ aka ná ntị banyere ihe ga-ekwe omume ịzụlite mmetụta ndị a na-esote mgbe ị na-ede akwụkwọ Tricor:

Sistemụ Lymphatic / mgbasa ọbara: adịkarịghị - mmụba nke ọdịnaya mkpụrụ ndụ ọbara ọcha na haemoglobin,
Usoro nri: oge - mgbu afọ, ọgbụgbọ, ọgbụgbọ, ọgbụgbọ na afọ ọsịsa, mgbe ụfọdụ - ikpe nke pancreatitis,
Usoro akwara na uru ahụ: adịkarịghị - myositis, mgbasa myalgia, adịghị ike, nkwonkwo akwara, ọ na-esiri ike - rhabdomyolysis,
Imeju: mgbe mgbe - mmụba dị ala na mkpokọta nke serum transaminases, mgbe ụfọdụ - ịkpụ gallstones, ọ na - adịkarịghị - akụkụ nke ịba ọcha n'anya (n'ọnọdụ nke mgbaàmà - oria, itching - nnwale ụlọ nyocha, n'ihe banyere nkwenye nke nchọpụta ahụ, a na-akagbu ọgwụ ahụ),
Sistemụ ụjọ: adịkarịghị - isi ọwụwa, nsị mmekọahụ,
Ọkpụkpụ akụrụngwa: mgbe ụfọdụ - thromboembolism venous (nke nwere nkụda mmụọ nke akwara nke ukwuu, akwara umeji),
Akpụkpọ anụ na abụba subcutaneous: mgbe ụfọdụ - itching, ihe nfụkasị ahụ, mmeghachi omume na-akpata, urticaria, adịkarịghị - alopecia, adịkarịghị - photosensitivity na-eme na erythema, guzobe nodules ma ọ bụ blisters na mpaghara nke anụ ahụ kpughere radieshon UV ma ọ bụ ìhè anyanwụ (na N'okwu nke onwe - ka ejiri ogologo oge were mmepe nke enweghị nsogbu ọ bụla),
Ebe iku ume: odi ike obere - interstitial pneumopathy,
Ọmụmụ ụlọ nyocha: oge ụfọdụ - mụbara urea na creatinine n'ụbara.

Ihe ngbanwe

A machibidoro ya idebe Tricor n'ọnọdụ ndị a:

Ọrịa imeju na-arịa nnukwu ọrụ, ya na akụkụ arụ ọrụ,
Imeju imeju
Nnukwu gbasara akụrụngwa,
Ọrịa mgbu na-efe efe ma ọ bụ ọnya na-adịghị ala ala,
Ọrịa gallbladder na hypofunction ya,
Ime na inye ara,
N’agbata afọ 18
Onwe onye n’onwe ya na mejuputa ogwu ahu.

Edebere ya site na ịkpachara anya nye ndị nwere ọrịa ịba ọcha n'anya na / ma ọ bụ ọdịda akụrụngwa, maka hypothyroidism, ndị ọrịa na-a abuseụbiga mmanya ókè, ndị ọrịa agadi, nwere akụkọ ọrịa ọrịa akwara, na mgbe a na-a whileụ ọgwụ mkparịta ụka, HMG-CoA reductase inhibitors.

Dodoụbiga ya ókè

Achọpụtabeghi na ị symptomsụbiga ihe ọdoụ Overụ na ntuziaka ahụ. Onwe ugbu a enweghi data nyocha gbasara ịdoụ ọgwụ ọgwụ ike.

Amaghị ọgwụ ahụ. Usoro ọgwụgwọ a na-egosi Symptomatic. Usoro ọgwụgwọ adịghị irè.

Analogs nke Tricor, ọnụahịa dị na ahịa ọgwụ

Ọ bụrụ na ọ dị mkpa, ịnwere iji dochie iji Tricor jiri mmanu nọ n'ọrụ - ọgwụ ndị a bụ:

Fonfibrate Canon (site na 320.90 rubles),
Lipantil (site na 845.00 rub),
Lipantil 200 M (site na 868.80 rubles).

Yiri na eme:

Mgbe ị na-ahọrọ analogues, ọ dị mkpa ịghọta na ntuziaka maka iji Tricor 145 mg, ọnụahịa na nyocha anaghị emetụta ọgwụ ndị nwere mmetụta yiri nke ahụ. Ọ dị mkpa ịnweta ndụmọdụ nke dọkịta na ịghara ime mgbanwe ọgwụ ọ bụla.

Ọnụahịa dị na ụlọ ahịa ọgwụ na Moscow na Russia: Tricor 145 mg 30 mbadamba 30 - site na 864 ruo 999 rubles, dị ka ọgwụ 729 si kwuo.

Chekwaa n’ebe kpọrọ nkụ na okpomọkụ ruo 25 Celsius. Ekwela ka ụmụaka ghara iru ya. Ndụ shelf bụ afọ 3.

Ọnọdụ nke inyefe ọgwụ n'ụlọ ọgwụ bụ ọgwụ ọgwụ.

Nyocha 3 maka "Tricor 145 mg"

Tricor 145 adabaghịrị m, mgbe m nwesịrị ya ruo ọnwa abụọ, ihe mgbu na paresis nke ahụ mụbara, ike akwara niile (enwere m ọnya ọbara 8 afọ gara aga, paresis nke nwere aka nri na-adịgide ugbu a) Enweghị mgbanwe ọ bụla hụrụ, ọ bụ naanị adịghị ike na ahụ dum. iju.

Mmetụta ọgwụ ahụ nwere. Comfortfọdụ ahụ erughị ala n’ahụ niile. Na njedebe nke nnabata, ihe niile gafere. Nsonaazụ nke, site na enyemaka nke Tricorr, achọrọ m iji nweta - m mezuru. A na - ezere nlọghachi ọbara-ọbara (intraocular hemorrhage)

Emebibeghị m ntụkwasị obi na ọgwụ ndị a - n'oge nchịkwa, enwere ahụ erughị ala.

Mwepụta wepụtara ya na ihe mejupụtara

A na - enweta tricor na usoro usoro ogwu a:

Mbadamba ihe osise, 145 mg: oke, ọcha, na akara ụlọ ọrụ dị n'otu akụkụ nke mbadamba ihe ahụ na ederede "145" n'akụkụ nke ọzọ (pcs iri abụọ na blisters, na katọn 1, 2, 3, 5, 9 ma ọ bụ 10) blisters, pcs 14 n'ime blisters, na ngwugwu kaadiboodu 2, 6 ma ọ bụ 7 blisters, maka ụlọ ọgwụ - pcs 10 n'ime blisters, na igbe kaadi 28 ma ọ bụ blisters 30),
Mbadamba ihe osise, 160 mg: nke ukwuu, na-acha ọcha, na akara ụlọ ọrụ dị n'otu akụkụ nke mbadamba ya na ihe e dere na "160" n'akụkụ nke ọzọ (pcs iri abụọ na blisters, na katọn 1, 2, 3, 4, 5, 9 ma ọ bụ blisters 10, pcs 14 n'ime blisters, na ngwugwu kaadiboodu 2, 6 ma ọ bụ 7 blisters).

Nchịkọta nke ọ bụla nwekwara ntuziaka maka ojiji nke Tricor.

Ihe mejupụtara kwa mbadamba ihe nkiri

ihe na-arụ ọrụ: fenofibrate (nke micronized n'ụdị nanoparticles) - 145 mg ma ọ bụ 160 mg,
ihe inyeaka: sodium lauryl sulfate, sodium stearyl fumarate, crospovidone, colloidal silicon dioxide, scusum sodium, sucrose, lactose monohydrate, microcrystalline cellulose, hypromellose, magnesium stearate, povidone,
n'ọbọ ihe nkiri: Opadry OY-B-28920 (titanium dioxide, talc, xanthan gum, mmanya polyvinyl, soy lecithin).

Mlọ ọgwụ

Fenofibrate na-ezo aka na usoro nke fibroic acid. Usoro nke ihe o mere jikọtara ya na mmụba nke RAPP-alpha (ndị na - anabata ndị na - eme ihe na - arụ ọrụ nke peroxisome proliferators). N'ihi mmegharị nke RAPP-alfa, a na-emezi lipolysis nke atherogenic lipoproteins ma na-enwewanye ntụpụ ha site na plasma. Nke a na - eduga na mmụba na njikọta nke apoproteins A-1 na A-2 (Apo A-1 na Apo A-2). N'ihi nsonaazụ nke a, a na-ebelata ọdịnaya nke obere nke LDL (njupụta lipoproteins dị obere) yana VLDL (njupụta lipoproteins dị obere) ma na-abawanye ọdịnaya nke HDL. Fenofibrate na-abawanye ọnụọgụ nke ọgwụ LDL ma na-ebelata ọdịnaya nke obere ihe na oke nke LDL, mmụba nke ọnụ ọgụgụ nke a na-ahụ na ndị ọrịa nwere ọrịa ngwụrọ atherogenic (nke ka ukwuu, nsogbu ndị dị otú ahụ na-eme na ndị mmadụ n'ihe ize ndụ nke ọrịa obi obi).

N'ihi ihe omumu ihe omumu, emere ka egosiputa na fenofibrate belata mkpokoro nke triglycerides site na 40-55% na cholesterol zuru oke site na 20-25% na mmụba nke cholesterol na HDL site na 10-30%. N'ime ndị ọrịa nwere hypercholesterolemia nke cholesterol dị ala na LDL (site na pasent 20 ruo 35) n'oge fenofibrate, ụdị ụdị ndị a na-ebelata: “LDL-cholesterol / HDL-cholesterol”, “kọlestrọl / HDL-cholesterol”, “Apo B / Apo A-1 "(oke ndị edepụtara bụ akara nke ihe egwu atherogenic).

Ebe ọ bụ na Tricor na-emetụta oke nke triglycerides na LDL cholesterol, ojiji ya na hypercholesterolemia, na-esonye ma ghara iso ya na hypertriglyceridemia (gụnyere hyperlipoproteinemia nke abụọ, dịka ọmụmaatụ, ụdị ụdị ọrịa shuga 2).

N'oge a na-eji fenofibrate, mbelata dị ukwuu na ọbụna mkpofu ego cholesterol (tuberous na tendon xanthomas) na enwere ike kpamkpam. N'ime ndị nwere oke fibrinogen, a na-ahụta mbelata dị ukwuu na njirimara a n'okpuru mmetụta nke fenofibrate (dị ka ndị ọrịa nwere ịba ụba nke lipoproteins). Ọkwa nke akara ọzọ na-egosi ọnya, protein C-reactive na-agbadata site na usoro fenofibrate.

Tinyere ihe ndị ọzọ, Tricor na-enwe mmetụta uricosuric ma belata mkpụkọ uric acid ihe dị ka 25%, nke bụ uru ndị ọzọ maka ndị ọrịa nwere hyperuricemia na dyslipidemia.

Na nyocha anụmanụ, yana na nnwale ụlọ ọgwụ ahụ, egosiri na ọ na-ebelata nchịkọta platelet nke epinephrine, arachidonic acid na adenosine diphosphate.

Mlọ ọgwụ

Mbadamba ọgwụ tricor na usoro ọgwụ nke 160 mg nwere bioavailability dị elu karịa ụdị usoro ọgwụgwọ fenofibrate na mbụ.

Oke plasma na-erute mgbe awa 2-4 (mbadamba 145 mg) ma ọ bụ 4-5 awa (mbadamba mg mg 160). Ọ dabere na ị foodụ nri yana iji ọgwụ ogologo oge ọ na-akwụsi ike n'agbanyeghị agbụrụ onye ọrịa ahụ nwere.

Mgbe ị gachara Tricor, achọpụtaghị fenofibrate mbụ na plasma ọbara. Mmiri esterases na-agba ya mmiri. Ihe bụ isi plasma metabolite nke ọgwụ bụ fenofibroic acid, nke karịrị 99% jikọtara na protein plasma (albumin). Fenofibrate adịghị etinye aka na metabolism nke metabolsom ma ọ bụghị dochie anya enzyme CYP3A4.

Ọkara ọkara bụ ihe dịka awa iri abụọ. Routezọ kachasị mma na excretion bụ mmamịrị (n'ụdị conjugate nke glucuronide na fenofibroic acid). Fenofibrate fọrọ nke nta ka ekpochapụ kpamkpam n'ime ụbọchị 6. N'ime ndị agadi, mkpochapu fenofibroic acid anaghị agbanwe.

Achọpụtaghị mmetụta ahụ yana mgbe otu ọgwụ a rụtara, yana n'ihi ojiji ogologo oge. Ọkpụkpụ anụ ahụ maka iwepụ fenofibrate abaghị uru (n'ihi oke ijikọ protein protein).

Ihe ngbanwe

gbasara akụrụngwa nke ike ọ bụla,
ihe ngosiputa nke akuko banyere oria buwara
mmebi imeju (gụnyere ịba ọcha n'anya nke mmalite ama na biliary cirrhosis)
ọrịa akwara ma ọ bụ nke na-adịghị ala ala, belụsọ n'ụdị nnukwu ọrịa pancreatitis n'ihi nnukwu hypertriglyceridemia,
Akụkọ banyere ahuekere peanut, soya lecithin, ahụekere ma ọ bụ ngwaahịa ndị ọzọ metụtara ya na anamnesis (n'ihi ihe egwu nke ịba ọcha),
ụkọ nri lactase, ụyọkọ galactosemia, ọrịa nke galactose na glucose (ebe ọ bụ na mbadamba ndị ahụ nwere lactose).
isomaltase / sucrase enzyme erughi, fructosemia ịmụ nwa (ebe ọ bụ na sucrose bụ akụkụ nke mbadamba),
akụkọ banyere fototoxicity ma ọ bụ fotoensitization na ọgwụgwọ nke ketoprofen ma ọ bụ fibrates,
lactation
ụmụaka na ndị na-eto eto nọ n’agbata afọ 18,
hypersensitivity na fenofibrate, yana ihe ndi ozo nke ogwu.

A na-eji mkpachapụ anya eme ihe (a na-eji akọ dị akọ na ntị):

hypothyroidism
Ibu akuko banyere oria akwara
na nhazi nke hydroxymethylglutaryl coenzyme Ahibata ihe na - egbochi mgbochi (HMG-CoA reductase) ma ọ bụ ọgwụ anticoagulants,
ị alcoholụbiga mmanya ókè
nká
oge ime.

Agụụ: ntuziaka maka ojiji (usoro na usoro)

Ekwesịrị iji okwu ọnụ mee ihe, n'agbanyeghị oge nri. A ga-elorịrị mbadamba a kpamkpam na-ata ata, jiri mmiri zuru oke sachaa ya.

Achọrọ ka ọ nọgide na-agbaso na nri hypocholesterolemic pụrụ iche, nke enyere n'iwu tupu ịmalite ọgwụgwọ ọgwụ.

Usoro a tụrụ aro bụ otu mbadamba (145 mg ma ọ bụ 160 mg) otu ugboro n’ụbọchị. Ndị ọrịa buburu fenofibrate na 200 mg capsules ma ọ bụ mbadamba 160 mg, otu Capsule ma ọ bụ otu mbadamba otu ugboro kwa ụbọchị, nwere ike gbanwee na-ewere otu mbadamba ọgwụ Traicor 145 mg ma ọ bụ mg mg 160 na-enweghị mmezi dose ọzọ.

Maka ndị agadi (nke nwere ọrụ ezumike nkịtị), a na-enye ọgwụ ahụ ka a na-enye ya.

Ekwesịrị ịtụle ịdị irè nke ọgwụgwọ site na ịta nke triglycerides, cholesterol na LDL na ọbara.Ọ bụrụ na mgbe ọtụtụ ọnwa gachara ọgwụgwọ (ọ na - abụkarị ọnwa atọ) ọ nweghị nsonaazụ, ọ dị mkpa ikpebi ịdị mkpa nke ọgwụgwọ ahụ ma nyekwa ndị na-eme con ma ọ bụ ọgwụgwọ ọzọ.

Nsonaazụ

Achọpụtara mmetụta na-adịghị mma nke Traicor n'oge ọmụmụ ihe na-achịkwa placebo:

sistem nri, imeju na ọnya biliary: oge - ihe mgbaàmà na ihe ịrịba ama nke eriri afọ (vomiting, ọgbụgbọ, mgbu afọ, flatulence, afọ ọsịsa), ụba transaminases, ụkwara nta - cholelithiasis, pancreatitis, adịkarịghị - ịba ọcha n'anya,
sisitemu ike gbasara akwara: mkpụrụedemede akwara nke ala ala akwara, thromboembolism akwara,
sistemụ akwara: enweghi oge - isi ọwụwa, adịkarịghị - ike ọgwụgwụ, ike ọgwụgwụ,
sistem mọzụlụ: ugboro ugboro - mmebi ahụ (myositis, adịghị ike anụ ahụ, mgbasa mgbasa, akwara umeji),
usoro omumu: enweghi ike - enweghi ike,
sistem lymphatic na ọbara: adịkarịghị - mbelata n'ọkwa ọbara ọbara, mbelata ọnụ ọgụgụ mkpụrụ ndụ ọbara ọcha,
dịghịzi usoro: adịghị ike - hypersensitivity,
akpụkpọ ahụ na abụba subcutaneous: ugboro ugboro - ọnya, itching, urticaria, na-adịkarịghị - fotoensitivity, ntutu isi oria,
ule nyocha nke ụlọ nyocha: ugboro ugboro - mmụba na serin creatinine, adịkarịghị - mmụba nke ịbara nitrogen urea ọbara.

Mmeghachi omume ọjọọ nke Traicor e dere n'oge iji ahịa azụmaahịa:

imeju na ọnya biliary: nsogbu nke cholelithiasis (cholangitis, cholecystitis, biliary colic), jaundice,
usoro iku ume: oria akpa ume,
sistem mọzụlụ: rhabdomyolysis,
akpụkpọ ahụ na abụba subcutaneous: mmeghachi omume anụ ahụ (nrịbama necrolysis na-egbu egbu, erythema multiforme).

Ntụziaka pụrụ iche

Tupu ịmalite fenofibrate, ọ dị mkpa iji duzie ọgwụgwọ kwesịrị ekwesị iji kpochapụ ihe kpatara hypercholesterolemia na ọrịa dịka hypothyroidism, dysproteinemia, ụdị ọrịa shuga na-achịkwaghị achịkwa 2, ọrịa nephrotic, ọrịa imeju na-egbochi, yana ị asụbiga mmanya ókè na nsonaazụ ọgwụ.

N'ime ndị ọrịa nwere hyperlipidemia, na-ewere ọgwụ mgbochi estrogen na-enwe ma ọ bụ estrogens, mmụba nke ọkwa lipid nwere ike ịbụ n'ihi oriri estrogen, yabụ, ọ dị mkpa iji chọpụta ụdị hyperlipidemia (nke mbụ ma ọ bụ nke abụọ).

N'ime afọ mbụ, ọnwa atọ ọ bụla na oge kwa oge mgbe a na-etinyekwu ọgwụgwọ, a na-atụ aro ka nyochaa ọkwa nke enzymes imeju. N'ihe banyere mmụba nke ọrụ transaminases ihe karịrị ugboro 3 ma e jiri ya tụnyere VGN (oke nke ụkpụrụ ahụ), a ga-akwụsị nchịkwa Tricor. Maka mgbaàmà ịba ọcha n'anya, a ga-enyocha ule ụlọ nyocha kwesịrị ekwesị, ọ bụrụ na enyochapụta nchọpụta ahụ, kwụsị ọgwụ ahụ.

Otu n'ime mmetụta fenofibrate bụ mmepe nke ọrịa ọrịa pancreatitis, ihe ndị nwere ike ibute ya bụ nnyonye anya na Tricor, arụmọrụ ọgwụ ezughi oke na ndị ọrịa nwere nnukwu hypertriglyceridemia, nsonaazụ nke abụọ (sediment ma ọ bụ ọnụnọ nke nkume na bile dupo, na-eke ihe mgbochi nke otu bile duct).

Ọrịa rhabdomyolysis n'oge ọgwụgwọ ọgwụ na-abawanye na ndị ọrịa nwere akụkọ banyere ọdịda akụrụ ma ọ bụ hypoalbuminemia. Mgbe ihe mgbaàmà nke nsị na-egbu egbu na akwara anụ ahụ (myositis, mgbasa myalgia, nsogbu, nkwonkwo akwara, mmụba nke ọkwa phosphokinase site na ihe karịrị 5 ugboro ma e jiri ya tụnyere VGN), a ga-akwụsị ịgwọ ọrịa fenofibrate.

Nlekọta oge nke Tricor nwere fibrates ndị ọzọ ma ọ bụ HMG-CoA reductase inhibitors na-eme ka ohere dị oke egwu belata na akwara, karịchaa ma ọ bụrụ na onye ọrịa ahụ enweworị ọrịa akwara tupu ọgwụgwọ. Maka nke a, ojiji a jikọtara iji ọgwụ eme ihe na statins bụ naanị maka nsogbu dyslipidemia jikọtara ọnụ na ọghọm nke ọrịa obi na ọrịa na akarị ọrịa akwara, yana nyocha nlezianya anya na mmalite nchọpụta nke akara nke mmerụ ahụ na-egbu egbu.

Ọ bụrụ na n'oge usoro ọgwụgwọ nke itinye uche nke creatinine na-ebili karịa 50% site na VGN, ekwesịrị ịkwụsị nchịkwa nke Tricor. A na-atụ aro ka njikwa ikike creatinine na-enyocha mgbe niile n'ime ọnwa atọ mbụ, yana oge ụfọdụ n'oge usoro ọgwụgwọ ọzọ.

Ime na lactation

Ihe omuma banyere iji ogwu eme ihe n’ebe umu nwanyi di ime ezughi ezu. Na nyocha ndị e mere na anụmanụ, enweghị mmetụta teratogenic. Site na iji fenofibrate mara ka ẹmbrayoxic dị mgbe a na-ele ọgwụ nlere anya nke doses na aru nwanyi. Iji Tricor n'oge ime ga-ekwe omume naanị mgbe ị tụlechara nha uru nne na nna / n'ihe ize ndụ nke nwa ebu n’afọ.

Ihe omuma banyere uzo esi abanye fenofibrate ma obu metabolites ya n’ime mmiri ara ara ezughi oke, ya mere ojiji nke ogwu n’oge ara.

Mkparịta ụka ọgwụ ọjọọ

A ga-ejikọ tricor na ịkpachara anya na ọgwụ na ihe ndị a:

anticoagulants maka nchịkwa ọnụ: fenofibrate na-eme ka ọgwụgwọ ọgwụgwọ anticoagulants dịkwuo elu ma nwee ike ịbawanye ohere nke ọbara ọgbụgba (a na-atụ aro ka ị belata ọgwụ mbụ nke anticoagulants site n'ihe dị ka otu ụzọ n'ụzọ atọ ma mesịa jiri nwayọọ nwayọọ mụbaa ya),
cyclosporine: oke nrụrụ akụrụ (na-atụgharị) enwere ike, yabụ na ndị ọrịa a, ọ dị mkpa inyocha ọnọdụ akụrụ,
HMG-CoA reductase inhibitors (statins), ihe ndị ọzọ: ihe ọghọm nke oke mmerụ ahụ na-egbu egbu na-abawanye,
Nchịkọta thiazolidinedione (rosiglitazone, pioglitazone): enwere ike iwelata ntụgharị uche nke HDL cholesterol (enwere ike ịlele HDL cholesterol ịta ma kagbuo fenofibrate na mbelata nke ukwuu na njirimara a).

Ihe analogues nke Tricor bu Lipantil 200 M, Lipofen SR, Eclip, Trilipix, Lopid, Fenofibrat Canon, wdg.

Nyocha Traicore

Dabere na nyocha, Tricor na-anagide ọrụ bụ isi - iwetulata cholesterol na triglycerides. Mgbe a na-a withụ ọgwụ ahụ, ndị ọrịa chọpụtara iwu ịba ọcha n’anya nke ọbara na LDL na HDL, belata ihe mgbu n’ụkwụ, belata. Agbanyeghị, ọtụtụ mgbe na ozi ha, ndị ọrụ na-akọwapụta nsonaazụ nke fenofibrate, dị ka ọgbụgbọ, mgbu afọ na olu, flatulence, adịghị ike n'ozuzu, mgbu akwara, ndọpụ uche, ịdị umengwụ, na mbelata ọbara mgbali. Ọdịmma ọzọ nke ọgwụ ahụ, ndị ọrịa na-atụle ọnụ ahịa ya dị elu.