Mkpụrụ akwụkwọ sirinji maka insulin humulin: gịnị ka ọ bụ, ọnụahịa na nyocha

Ọgwụ antidiabetic Humulin NPH nwere insulin-isophan, nke nwere oge ọrụ. Ezubere ya maka iji ya na-aga n'ihu iji nwee ike ịkwaa ọkwa glucose ọbara n'ime oke kwesịrị.

Enwere dị ka nkwusioru maka nchịkwa subcutaneous na vials na USA site na Eli Lilly na Companylọ ọrụ. Ma ụlọ ọrụ French Lilly France na-emepụta insulin Humulin NPH n'ụdị katriji jiri pen sirinji.

Ọgwụ nwere ọdịdị nke nkwụsị nke agba ma ọ bụ ajị agba.

Mmetụta ọgwụ na-akpata bụ mbelata nke glucose ọbara n'ihi mmụba ya na mkpụrụ ndụ yana anụ ahụ na-eji Humulin NPH. Na mellitus na-arịa ọrịa shuga, a na-ebelata mmepụta homonụ a na-eme ka ọ bụrụ nke na-achọ ọgwụ iji dochie hormone.

Ọgwụ na-abawanye uru glucose site na mkpụrụ ndụ chọrọ nri nri. Insulin na-anabata ndị na-anabata ihe pụrụ iche n’elu elu sel, nke na-akpali ọtụtụ usoro mmiri ọgwụ, nke gụnyere, nke ka nke, nhazi nke hexokinase, pyruvate kinase, glycogen synthetase.

Thega n’arụ glucose na anụ ahụ n’ọbara na-abawanye, ebe ọ na-ebelata.

Ngwongwo ogwu

Mmetụta ọgwụgwọ ahụ na-amalite otu awa mgbe ogwu ogbugba ahụ gasịrị.
Mmetụta na-ebelata shuga na-ewe ihe dị ka awa 18.
Mmetụta kasịnụ bụ ka elekere abụọ gachara ruo awa 8 ruo oge nchịkwa.

Suchdị mgbanwe dị otú a na etiti ọgwụ ọgwụ na-arụ ọrụ dabere na ebe nchịkwa nke nkwusioru yana ọrụ moto nke onye ọrịa. Ekwesiri iburu n'uche akụrụngwa ndị a mgbe ị na-enye usoro nhazi usoro yana usoro nchịkwa.

Nyere ogologo oge nke mmetụta ahụ, Humulin NPH ka edebere ya na insulin nwa obere na nke ultrashort.

Nkesa na mwepu sitere na aru:

Insulin Humulin NPH abanyeghị n'ihe mgbochi ọbara hematoplacental, mmiri ara ehi ewepụtabeghịkwa ya.
Emegharia imeju na akụrụ site na insulinase enzyme.
Mkpocha ọgwụ a tumadi site na akụrụ.

Mmeghachi omume ndị a na-achọghị na akụkụ ndị a gụnyere:

hypoglycemia bụ nsogbu dị egwu na iji ọgwụ ezughi oke. Egosiputa site na mwepu nke mmụọ, nke enwere ike ghaghae anya na hyma nke hyperglycemic.
Ngosiputa nfụkasị na saịtị ịgba nrị (redness, itching, swelling),
igbochi
mkpụkpu ume
hypotension
urticaria
tachycardia
lipodystrophy - mpaghara atrophy nke abụba subcutaneous.

Iwu iwu izugbe

Ekwesịrị ịnye ọgwụ ahụ n'okpuru anụ ubu, hips, isi ma ọ bụ mgbidi afọ, yana mgbe ịgba ọgwụ intramuscular nwekwara ike.
Mgbe ogwu ogbugba ahụ, ịkwesighi ịpị aka ike ma mechie mpaghara mwakpo ahụ.
Amachibidoro iji ọgwụ eme ihe.
A na - ahọrọ ọgwụ dum n'otu n'otu site na endocrinologist ma dabere na nsonaazụ nyocha ọbara maka shuga.

Njirimara nke ọgwụ

A na-eji ọgwụ ahụ eme ihe n'ihu ọnụnọ shuga na-akpata insulin na ụdị ọrịa shuga mellitus 2 n'oge oge mmegharị ahụ.

E nwere ọtụtụ ụdị ọgwụ ọgwụ Humulin.

Ọgwụ ndị a dịgasị iche n'oge arụ ọrụ n'ahụ.

Ruo taa, ụdị ọgwụ ndị a dị na ahịa ọgwụ:

Insulin Humulin P (nchịkwa) - bụ ọgwụ na - eme obere oge.
Humulin NPH bụ ọgwụ na-ekpughe ihe na-ajụ, nke na-amalite igosipụta ọrụ otu awa mgbe nchịkwa gasịrị, a na-enwetakwa nsonaazụ kachasị mgbe awa isii ruo asatọ.
Insulin Humulin M3 bu ogwu nke oge ekpughere. Odikwa n'ụdị nkwusioru nke abụọ, nke mejupụtara insulin Humulin Regular na Humulin NPH.

Ebumnuche kachasị na ọgwụ a bụ iji duzie usoro glucose metabolism, yana iji mee ka anabolism protein dị ngwa.

A na-ejikwa Humulin Regulator na-emeso ụdị ọrịa shuga 2 ọrịa shuga n'ihu ihe ndị a:

ọ bụrụ na n'oge usoro ọgwụgwọ dị mgbagwoju anya enwere ngosipụta nke iguzogide ọgwụ belata shuga,
mmepe nke ketoacidosis,
ọ bụrụ na ọrịa febrile na-efe efe,
nsogbu ndị metabolic na-akpata
ọ bụrụ na, ọ dị mkpa ịnyefe onye ọrịa na ogologo oge insulin na-agwọ ọrịa.

Enwere ike igosi insulin ọgwụ ọgwụ Humulin n'ụzọ abụọ:

Nkwụsị maka ịgba ntụtụ n’ahụ.
Ngwọta maka ntụtụ.

Ruo taa, enwere ọtụtụ ọgwụ nwere ike dochie Humulin. Ndị a bụ analog ọgwụ nwere na ha mejupụtara otu ọrụ umi - insulin. Dochie ndị a gụnyere:

Actrapid na Apidra,
Biosulin na Berlsulin,
Gensulin na isofan insulin,
Kemgbe ụwa,
Lantus na Pensulin.

N'ọnọdụ ụfọdụ, ojiji nke proginine hagedorn ga-ekwe omume. Amachibidoro ịhọrọ ma ọ bụ dochie ọgwụ ahụ n'onwe gị. Naanị dibịa na-aga ahụ nwere ike ịkọtara onye ọrịa ahụ ọgwụ dị mkpa iji usoro ọgwụgwọ kwesịrị ya, na-eburu n'uche ogo ọrịa na njiri mara mmadụ.

Ntụziaka maka ojiji insulin Humulin NPH na M3: ọnụ ahịa ọgwụ ahụ na nyocha

Humulin NPH na usoro ndi ozo n’otu ogwu ogwu bu ogwu eji eme ndi mmadu n’aria oria.

Ogwu nwere ihe okike na-eme ka okpukpo ya di nkpa, dika emere ya na ntinye insulin ndi mmadu mebere.

Ebumnuche bụ isi nke ihe mmadụ mepụtara bụ iji belata ọkwa glucose dị n’ọbara site n’itinye ya n’ime anụ ahụ na itinye ya n’ime sistem metabol nke sel.

Humulin na-bụ ọnye?

Taa, enwere ike ịhụ okwu ahụ Humulin n'aha ọtụtụ ọgwụ ndị e mere iji belata shuga ọbara - Humulin NPH, MoH, Regular and Ultralent.

Ọdịiche dị na usoro maka imepụta ọgwụ ndị a na-enye ngbanye shuga ọ bụla na njirimara nke ya. A na-atụle ihe a mgbe ị na-edepụta ọgwụgwọ maka ndị nwere ọrịa shuga.

Na mgbakwunye na insulin (isi ihe mejupụtara, nke a tụrụ na IU), ọgwụ nwere ndị nwere ihe dị ka mmiri mmiri, protamines, carbolic acid, metacresol, zinc oxide, sodium hydroxide, wdg.

A na-akwakọ homonụ a na-eme ka a mata na katriiki, vials, na sirinji sirinji. Ntụziaka ejikọtara na-agwa maka atụmatụ nke iji ọgwụ mmadụ.

Tupu ojiji agbanyeghi krisịlị na vials a ga-eme mkpatụ nke ọma; ihe niile dị mkpa maka ndọghachi azụ nke ọma ga - agbasa ha n'etiti ọbụ aka.

Oge kachasị adaba maka ndị ọrịa mamịrị bụ mkpịsị sirinji.

Iji ọgwụ ndị a kpọtụrụ aha na-enye ohere ịnweta ọgwụgwọ dị mma maka ndị ọrịa nwere ọrịa shuga, ebe ha na-enye aka na nnọchi nke adịghị ike zuru oke na nke adịghị ala nke homonụ endogenous nke pancreas. Denye Himulin (usoro onunu ogwu, regimen) kwesiri ibu ihe omumu ihe omumu. N’ọdị n’ihu, ọ bụrụ na ọ dị mkpa, dibịa na-aga ahụ nwere ike idozi usoro ọgwụgwọ.

N'ime ọrịa shuga nke ụdị nke mbụ, a na-enye insulin mmadụ ka ọ dịrị ndụ. Site na ndagide nke ụdị shuga nke 2, nke jikọtara ọnya na-efe efe, a malitere usoro ọgwụgwọ site na usoro dị iche iche. Ọ dị mkpa icheta na site na ọrịa nke chọrọ iwebata homonụ artificial n'ime ahụ, ị gaghị ajụ ọgwụ insulin, ma ọ bụghị na a gaghị egbochi nsonaazụ dị njọ.

Ọnụ ego ọgwụ nke otu ọgwụ ọgwụ a dabere na oge nke ime ihe na ụdị nkwakọ ngwaahịa.Ọnụ ego a na-eche na karama na-amalite site na 500 rubles., Ọnụ ahịa ya na katrized - site na 1000 rubles., N'ime mkpụrụ sirinji dịkarịa ala 1500 rubles.

Iji chọpụta usoro ị timeụ ọgwụ na oge ị theụ ọgwụ ahụ, ịkwesịrị ịkpọtụrụ endocrinologist

Ọ niile na-adabere dịgasị iche iche

A kọwara ụdị ego na nsonaazụ ahụ.

Emere ọgwụ a site na iji teknụzụ DNA, ma nwee nkezi oge ọ na-eme. Ebumnuche ebumnuche ọgwụ ahụ bụ ịhazi metabolism.

Ọ na - enyere aka egbochi usoro protein na - agbasa ma nweekwa anabolic na anụ ahụ. Humulin NPH na-abawanye ọrụ nke enzymes nke na-akpali nguzobe nke glycogen na akwara akwara.

Ọ na - eme ka olu nke abụba ghara ịba ụba, na - emetụta ọkwa nke glycerol, na - eme ka mmepụta protein na - akwalite oriri nke aminocarboxylic acid site na mkpụrụ ndụ akwara.

Analogs nke na-ebelata ọbara shuga bụ:

Actrafan NM.
Diafan ChSP.
Insulidd N.
Protafan NM.
Humodar B.

Mgbe ogwu ogbugba ahụ gasịrị, ihe ngwọta malitere ime ihe mgbe elekere 1 gachara, a na-enweta nsonaazụ zuru oke n'ime awa 2-8, ihe ahụ na-arụ ọrụ ruo awa 18-20. Oge a ga-eme maka homonụ ahụ dabere na oke ejiri, saịtị ịgba ntụtụ, yana ọrụ mmadụ.

Humulin NPH egosiputara na iji:

Ọrịa shuga na usoro insulin na-atụ aro.
Nke mbu choputara oria shuga.
Womenmụ nwanyị dị ime na-arịa ọrịa shuga na-arịa insulin.

Ntụziaka ahụ na-ekwupụtaghị ọgwụ ahụ maka ndị nwere hypoglycemia dị ugbu a, nke a na-egosipụta maka ịdalata glucose ọbara dị n'okpuru 3.5 mmol / L, na oke ịkpa ike - 3.3 mmol / L, na ndị ọrịa nwere oke mmetụta nke ọgwụ ahụ.
Mmetụta ndị nwere ike ime mgbe ị ofụ ọgwụ ahụ na-egosikarị:

Hypoglycemia.
Ngwakọta nke abụba.
Ọrịa systemic na allergies.

Banyere ịdoụbiga ọgwụ ókè, enweghị akara ụfọdụ doro anya nke ịdoụbiga mmanya ókè. A na-atụle ihe mgbaàmà bụ isi mmalite nke hypoglycemia. Ọnọdụ a na-esite na isi ọwụwa, tachycardia, ịsụsọ na ịchacha akpụkpọ ahụ. Iji zere nsogbu ahụike dị otú ahụ, dọkịta na-ahọrọ usoro ọgwụgwọ maka onye ọrịa ọ bụla n'otu n'otu, na-eburu n'uche ogo nke glycemia.

Site na ịdoụbiga ọgwụ ókè, hypoglycemia nwere ike ime.

Humulin M3, dị ka usọbọ gara aga, bụ ihe eji agbatị agbatị. Achọpụtara ya n'ụdị nkwusioru nke abụọ, katrized iko nwere insulin humulin mgbe niile (30%) na humulin-nph (70%). Ebumnuche bụ isi nke Humulin Mz bụ ịhazi metabolism metabolism.

Ọgwụ na-enyere aka iru akwara, na-ebuga glucose na aminocarboxylic acid ngwa ngwa n’ime sel nke akwara na akwara ndị ọzọ na-abụghị ụbụrụ. Humulin M3 na-enyere aka na akwara imeju na-agbanwe glucose na glycogen, na-egbochi gluconeogenesis ma na-agbanwe oke glucose na abụba subcutaneous na visceral.

Analogues nke ọgwụ bụ:

Protafan NM.
Farmasulin.
Actupid Flekspen.
Lantus Optiset.

Mgbe ịgba ọgwụ mgbochi gasịrị, Humulin M3 na-amalite ime ihe dị ka nkeji 30-60, a na-enweta nsonaazụ kachasị n'ime awa 2-12, oge ọrụ insulin bụ awa 24. Ihe ndị na-emetụta ọkwa nke ọrụ Humulin m3 na-esonyere na mpaghara ahọpụta yana ọgwụ mgbochi, yana anụ ahụ mmadụ na nri ya.

Ndị nwere ọrịa shuga chọrọ ọgwụgwọ insulin.
Womenmụ nwanyị dị ime na-arịa ọrịa shuga.

A na-enye ọgwụ mgbochi insulin n'ime ntụpọ hypoglycemia na hypersensitivity nke ihe mejupụtara. Ekwesịrị ịmalite ọgwụgwọ insulin n'okpuru nlekọta nke dọkịta, nke ga-ewepụ mmepe na nhụsianya nke hypoglycemia, nke nwere ike ịghọ, n'ọnọdụ kachasị mma, ihe kpatara nkụda mmụọ na enweghị uche, n'ihe kachasị njọ - mmalite nke ọnwụ.

N'oge ọgwụgwọ insulin, ndị ọrịa nwere ike ịnweta mmeghachi omume nfụkasị mpaghara, nke a na-egosipụtakarị site na itching, disloration, ma ọ bụ ọzịza nke anụ ahụ na saịtị ahụ. Akpụkpọ anụ ahụ bụ ihe emere n'ime ụbọchị 1-2, n'ọnọdụ ndị siri ike izu ole na ole chọrọ. Oge ụfọdụ mgbaama ndị a bụ ihe ama ama na-ezighi ezi.

Ọrịa sistemu na - akpata obere oge, mana ihe ngosipụta ya dị njọ karịa nke ndị gara aga, dị ka itching juputara, ura ume, ọbara mgbali elu, ọsụsọ gabigara ókè na ọnụego obi ngwa ngwa. N'ọnọdụ a kapịrị ọnụ, nfụkasị nwere ike itinye ndụ mmadụ n'ihe egwu, a na-edozi ọnọdụ ahụ site na ọgwụgwọ mberede, ojiji nke disensitization na dochie ọgwụ.

Edere ọgwụ ahụ maka ndị nwere ọgwụ insulin.

Humulin regula - obere eme

Humulin P bụ ihe mejupụtara DNA nke nwere mkpirikpi oge ikpughe. Ebumnuche bụ ebumnuche nke glucose metabolism. Ọrụ niile ekenyela ọgwụ ahụ yiri ụkpụrụ nke ekpughere humul ndị ọzọ.

Ekwuputara ihe ngwọta a maka ndị mmadụ na - arịa ọrịa shuga mellitus nke ụdị nke mbụ na nke abụọ, yana nguzogide anụ ahụ na ọgwụ ọgwụ hypoglycemic na ọgwụgwọ ọgwụ.

Edere usoro iwu Humulin:

Na ketoacidosis na-arịa ọrịa mamịrị.
Ketoacidotic na cope hymorosmolar.
Ọ bụrụ na ọrịa shuga pụtara n’oge a na-amụ nwa (ọ ga-eme ka nri gharazie isi ike).
Methodzọ n ’ụzọ dị iche iche e si agwọ ọrịa shuga na ọrịa.
Mgbe ị na-agbanye insulin agbatị.
Tupu ịwa ahụ, yana ọrịa metabolic.

A na - egbochi ọgwụ Humulin P n'ihe banyere ịgwọ ọrịa mmadụ na ọgwụ onye ahụ wee chọpụta hypoglycemia. Dọkịta n’otu n’otu na-edepụtara onye ọrịa ọgwụ ntụtụ na ọgwụ mgbochi n’eburu n’arụ glucose dị n’ọbara tupu e rie nri na mgbe 1-2 gachara. Na mgbakwunye, mgbe ị na-a doseụ ọgwụ, a na-elebara ọkwa shuga dị na mmamịrị na usoro ọrịa ahụ anya.

Ọgwụ a tụlere, n'adịghị ka ndị nke mbụ, enwere ike ịhazi ya intramuscularly, subcutaneously and intravenously. Ofzọ nchịkwa a na-ahụkarị bụ subcutaneous. N’ime ọrịa shuga na mgbagwoju anya yana coma na-arịa ọrịa shuga, a na-ahọrọ IV na IM injections. Na monotherapy, a na-enye ọgwụ ahụ ugboro 3-6 n'ụbọchị. Iji wezuga ọnọdụ nke lipodystrophy, a na-agbanwe ebe injections oge ọ bụla.

A na-ejikọ Humulin P, ma ọ bụrụ na ọ dị mkpa, na ọgwụ hormone nke ikpughe ogologo oge. Ihe ama ama analogues nke ogwu:

Actrapid NM.
Biosulin R.
Insuman Rapid GT.
Rosinsulin R.

Edere ọgwụ ahụ mgbe ọ na-agbanye insulin gbatịrị

Ọnụahịa nke ndị nọchiri anya ndị a na-amalite site na 185 rubles, a na-ewere Rosinsulin dị ka ọgwụ kachasị ọnụ, ọnụahịa ya taa karịrị 900 rubles. Iji dochie anya insulin na analog, kwesiri iwere ya na ndi dibia be bia. Aka anaakpo Humulin R bu Actrapid, nke kacha mara amara bu NovoRapid Flekspen.

Humulinultralente na-arụ ọrụ ogologo oge

Insulin Humulin ultralente bụ ọgwụ ọzọ akọwapụtara maka iji ndị ọrịa nwere ọrịa shuga na-akpata insulin na-akpata ọrịa shuga. Ngwaahịa a sitere na DNA ọgwụ ọzọ ma bụrụ ihe na-arụ ọrụ ogologo oge.

A na-eme ka nkwusioru ahụ rụọ ọrụ mgbe awa atọ gachara ịgba ọgwụ, a na-enweta nsonaazụ kachasị n'etiti awa iri na asatọ.

Ntuziaka maka iji gosipụta na oge kachasị elu nke Humulinultralente bụ awa 24-28.

Dọkịta debere ọgwụ maka onye ọrịa ọ bụla n’otu n’otu, n’iburu n’obi ọnọdụ onye ọrịa ahụ. A na-eme ọgwụ ahụ n'enweghị nsogbu, a na-eme inje in miri n'okpuru anụ ahụ 1-2 ugboro n'ụbọchị. Mgbe a na-ejikọ Humulin Ultralente na hormone ọzọ, na-agba ya ozugbo.

Mkpa insulin na-abawanye ma ọ bụrụ na mmadụ na-arịa ọrịa, na-enwe nrụgide, na-a oụ ọgwụ mgbochi, glucocorticoids ma ọ bụ homonụ thyroid. Na, n'ụzọ megidere, ọ na-ebelata site na ọrịa imeju na akụrụ, ebe na-ewere MAO inhibitors na beta-blockers.

Analogues nke ọgwụ ahụ: Humodar K25, Gensulin M30, Insuman Comb na Farmasulin.

Tụlee contraindications na nsonaazụ ya.

Dịka humulins niile, a na - egbochi insulin Ultralente n'ọnọdụ nke hypoglycemia na - aga n'ihu na ịnwe ike na - emetụta akụkụ nke ngwaahịa ahụ.

Dika ndi okacha mara si kwuo, nsogbu adighi adighi egosiputa onwe ya dika ihe mmeghachi ahu.

Ihe ga - ekwe omume pụta ntụtụ ka ekpughere site na lipodystrophy, ebe ọnụego anụ ahụ na - adị n'ihu anụ ahụ na - agbada, yana nguzogide insulin.

N'ọnọdụ ndị a na-adịghị ahụkebe, ọgwụ ahụ na-akpata mmeghachi ahụ nfụkasị.

Akwukwo ana - ewu ewu nke humulin - Protaphane

Ekwuputara insulin Protafan NM maka oria shuga nke oria nke mbu na nke abuo, maka ikike nke okachasi nke sulfonylurea, maka oria na-agbaghari oria shuga, n’oge ogwugwo ya na mgbe akwuchara ya.

Edere Protafan onye ọrịa ọ bụla n'otu n'otu, na-eburu n'uche ahụ ya mkpa. Dịka ntuziaka ahụ si dị, mkpa ịba ahụ homonụ bụ 0.3 - 1 IU / kg / ụbọchị.

Mkpa ahụ na-abawanye na ndị ọrịa na-eguzogide insulin (na-egbochi nzaghachi metabolic nke mkpụrụ ndụ na insulin), ọtụtụ mgbe nke a na-eme ndị ọrịa n'oge oge uto na ndị nwere oke ibu.

Ọga dibịa bekee ga-agbazi mmezi nke ọgwụ ahụ ma ọ bụrụ na onye ọrịa ebilite ọrịa concomitant, ọkachasị ma ọ bụrụ na ọrịa na-efe efe. A na-edozi usoro onunu ogwu maka ọrịa nke imeju, akụrụ na ọrịa nke gland thyroid.

A na - eji Protafan NM eme ihe dị ka ọgwụ nro n'okpuru ọgwụ monotherapy yana yana insulins dị mkpụmkpụ ma ọ bụ ngwa ngwa.

Humulin insulin: nyocha, ọnụahịa, ntuziaka maka ojiji

Na 1 ml. Ọgwụ Humulin Humulin nwere 100 IU nke insulin na-emegharị mmadụ. Ngwunye ndị na-arụ ọrụ bụ insulin na-akwụ ụgwọ 30% na 70% insulin isofan.

A na - eji ihe inyeaka:

ihe metacresol
phenol
sodium hydrogen phosphate heptahydrate,
hydrochloric acid,
glycerol
zinc oxide
protamine sulfate,
sodium hydroxide
mmiri.

Mpempe mwepụta

Ntinye ọgwụ mgbochi insulin Humulin M3 dị n'ụdị nkwusioru maka nchịkwa subcutaneous na karama 10 ml, yana na katriiki 1.5 na 3 ml, nke akwakọtara na igbe nke 5 iberibe. Ezubere Cartridges maka ojiji na sirinjin Humapen na BD-Pen.

Ọgwụ nwere mmetụta hypoglycemic.

Humulin M3 na-ezo aka na ọgwụ ọgwụ ndị a na - ejikọghachi ọnụ, insulin bụ nkwụsị ụzọ nkwụ nke abụọ nke oge eji arụ ọrụ.

Mgbe iwebata ọgwụ ahụ, ịdị irè nke ọgwụ na-apụta mgbe oge 30-60 gasịrị. Mmetụta kachasị dị na elekere abụọ ruo awa iri na abụọ, ọnụọgụ oge nke nsonaazụ ahụ bụ awa 18-24.

Ọrụ insulin nke Humulin nwere ike ịdị iche dabere na ebe nlekọta nke ọgwụ, izizi nke usoro ahọpụtara, mmega ahụ nke onye ọrịa, nri na ihe ndị ọzọ.

Isi mmetụta nke Humulin M3 metụtara na nhazi nke usoro ntụgharị glucose. Insulin nwekwara mmetụta anabolic. N'ihe fọrọ nke nta ka ọ bụrụ na anụ ahụ niile (ma e wezụga ụbụrụ) na akwara, insulin na-eme ka nnabata nke glucose na amino acids nwee ume intracellular.

Insulin na - enyere aka ịgbanwe glucose ka ọ bụrụ glycogen, ọ na - enyekwa aka ime ka oke shuga ghara abụba ma gbochie gluconeogenesis.

Ihe ngosi maka iji ya na mmetụta ndi ozo

Ọrịa shuga mellitus, nke a na-atụ aro ọgwụgwọ insulin.
Ọrịa shuga (ọrịa shuga nke ụmụ nwanyị dị ime).

Amalite hypoglycemia.
Hypersensitivity.

Ọtụtụ mgbe n'oge ọgwụgwọ insulin insulin, gụnyere Humulin M3, a na-ahụ mmepe mmepe nke hypoglycemia. Ọ bụrụ na o nwere ọdịdị siri ike, ọ nwere ike ịkpasu coma hypoglycemic (nkụda mmụọ na ọnwụ nke mmụọ) yana ibute ọnwụ onye ọrịa.

N'ime ụfọdụ ndị ọrịa, mmeghachi omume nfụkasị ahụ nwere ike ịpụta, gosipụtara site na nchapu akpụkpọ ahụ, ọzịza na ọnya na-agba ya. Dị ka ọ na-adị, mgbaàmà ndị a na-apụ n'anya n'onwe ha n'ime ụbọchị ole na ole ma ọ bụ izu mgbe ịmalitere ọgwụgwọ.

Mgbe ụfọdụ, nke a enweghị ihe jikọrọ iji ọgwụ ahụ n'onwe ya, mana ọ bụ nsonaazụ nke mmetụta nke ihe ndị dị na mpụga ma ọ bụ ọgwụ ezighi ezi.

Enwere ngosipụta nfụkasị nke ọdịdị usoro. Ha anaghị adịkarị obere, mana ọ ka njọ. Site na mmeghachi omume ndị dị otú ahụ, ihe ndị a na-esote:

iku ume siri ike
juputara itching
obi obi
dobe n'ọbara
mkpụkpu ume
igba oke onu.

N'okwu ndị kachasị njọ, akwara nwere ike ibute ndụ onye ọrịa ma chọọ nlekọta ahụike mberede. Mgbe ụfọdụ, a ga - achọ insulin dochie ma ọ bụ enweghị nchekwube.

Mgbe ị na-eji insulin anụmanụ, nguzogide, mmịnye ọgwụ, ma ọ bụ lipodystrophy nwere ike ịmalite. Mgbe ị na-ede akwụkwọ insulin Humulin M3, ihe ga-ekwe omume nke ihe ndị dị na ya pụta bụ ihe efu.

Nlekọta insulin

Iji merie ọgwụ ahụ n'ụzọ ziri ezi, ị ga-ebu ụzọ rụọ ụfọdụ usoro mbido. I kwesịrị ibu ụzọ chọpụta ebe ntụtụ gị dị, hichaa aka gị nke ọma ma hichaa ebe a na akwa mmanya nwere.

Mgbe ahụ ịkwesịrị iwepu okpu nchebe na agịga syringe, dozie akpụkpọ ahụ (gbatịa ma ọ bụ tuo ya), fanye agịga ma mee ntụtụ. Mgbe ahụ, a ga-ewepụ agịga ahụ ruo ọtụtụ sekọnd, na-enweghị rubrap, jiri akwa nhicha ihe na-etinye ebe ntụtụ. Mgbe nke ahụ gasị, site na enyemaka nke okpu na-echebe, ịkwesịrị ihipu agịga ahụ, wepụ ya ma tinye okpu ahụ na pen sirinji.

Cannotnweghi ike iji otu agịga mkpụrụ mkpịji ahụ ugboro abụọ. A na-eji vial ma ọ bụ katriki rụọ ọrụ ruo mgbe ọ tọgbọ chakoo, mgbe ahụ tụfuo. A na-ezube ihe eji eme ihe eji arụ ọrụ.

Dodoụbiga ya ókè

Humulin M3 NPH, dị ka ọgwụ ndị ọzọ na otu ọgwụ a, enweghị nkọwa ziri ezi nke ịdoụbiga mmanya ókè, ebe ọkwa glucose dị n'ọbara ọbara na-adabere na mmekọrịta dị n'etiti ọkwa glucose, insulin na usoro metabolic ndị ọzọ. Ma, ịdoụ ọgwụ insulin karịrị akarị, ọ nwere ike imebi ihe ọ bụla.

Hypoglycemia na-etolite n'ihi esemokwu dị n'etiti ọdịnaya insulin na ụgwọ plasma na ume ọrụ yana nri oriri.

Ihe mgbaàmà ndị a bụ njirimara nke ịba ụba hypoglycemia:

iju
tachycardia
vomiting
ọsụsọ gabigara ókè,
pallor nke anụ ahụ
ịma jijiji
isi ọwụwa
ndaba.

N'ụfọdụ, dịka ọmụmaatụ, nwere ogologo ọrịa shuga mellitus ma ọ bụ nyocha ya anya, ihe ịrịba ama nke hypoglycemia nwere ike gbanwee. Enwere ike igbochi hypoglycemia dị nwayọ site na ị gluụ glucose ma ọ bụ shuga. Mgbe ụfọdụ ị nwere ike ịhazigharị ọgwụ nke insulin, nyochaa nri ma ọ bụ gbanwee mmega ahụ.

A na-ejikarị hypoglycemia dị ala site na nchịkwa subcutaneous ma ọ bụ nchịkwa intramuscular nke glucagon, ihe ndị na-esote carbohydrates. N'ọnọdụ siri ike, na ọnụnọ nke nsogbu akwara ozi, nkwarụ ma ọ bụ coma, na mgbakwunye na ntụtụ glucagon, a ga-achịrị glucose na-agba agba.

N'ọdịnihu, iji gbochie nlọghachi nke hypoglycemia, onye ọrịa ahụ kwesịrị iri nri nwere carbohydrate. Ọnọdụ hypoglycemic dị oke egwu chọrọ ụlọ ọgwụ mberede.

Mkpakọrịta ọgwụ ọgwụ NPH

A na-eme ka arụmọrụ Humulin M3 dị elu site na ị drugsụ ọgwụ mkpịsị hypoglycemic, ethanol, ọgwụ salicylic acid, monoamine oxidase inhibitors, sulfonamides, ndị na-egbochi ACE, ndị na-anabata angiotensin II, ndị na-abụghị nhọrọ beta-blockers.

Ọgwụ Glucocorticoid, homonụ na-eto eto, ọgwụ mgbochi mkpịsị nke ede, danazole, homonụ thyroid, thiazide diuretics, beta2-sympathomimetics na-eduga na mbelata mmetụta hypoglycemic nke insulin.

Mee ka ọ dị ike, ma ọ bụ n'ụzọ ọzọ, mee ka ịdabere na insulin nwere ike nke lancreotide na analogues nke somatostatin.

Ọrịa hypoglycemia bụ lubricated mgbe na-ewere clonidine, reserpine na beta-blockers.

Usoro ire, nchekwa

Humulin M3 NPH dị n'ụlọ ahịa ọgwụ naanị site na ndenye ọgwụ.

Ekwesịrị ịchekwa ọgwụ a na okpomọkụ nke ogo 2 ruo 8, enweghị ike kpọnwụrụ ma kpughee ìhè anyanwụ na ikpo ọkụ.

Enwere ike idobe vial insulin nke NPH na-ekpori ndụ na 15 ruo 25 ruo ụbọchị 28.

N'okpuru ọnọdụ ọnọdụ okpomọkụ achọrọ, a na-echekwa nkwadebe NPH ruo afọ 3.

Ntụziaka pụrụ iche

Akwụsịghị ọgwụgwọ ma ọ bụ ịhọpụta ọgwụgwọ ezighi ezi (ọkachasị ndị ọrịa insulin) nwere ike ibute mmepe nke ọrịa ketoacidosis ma ọ bụ ọrịa hyperglycemia, nke nwere ike itinye ndụ onye ọrịa n'ihe egwu.

N'ime ụfọdụ mmadụ, mgbe ị na-eji insulin eme ihe, ihe mgbaàmà nke hypoglycemia na-abịanụ nwere ike ịdị iche na mgbaàmà njirimara nke insulin nke sitere anụmanụ, ma ọ bụ nwee ngosipụta dị ala.

Onye ọrịa ahụ kwesịrị ịmara na ọ bụrụ na ọkwa glucose ọbara dị mma (dịka ọmụmaatụ, yana ọgwụgwọ insulin siri ike), mgbe ahụ ihe mgbaàmà ndị na-egosi hypoglycemia na-abịanụ nwere ike ịpụ.

Ngosiputa ndi a nwere ike isi ike ma obu gosiputa iche iche ma oburu na mmadu ewere beta-igbochi ma obu ibu oria mamelit ogologo oge, ya na oburu onye n’aria mamedi.

Ọ bụrụ n’agagaghị hyperglycemia, dị ka hypoglycemia, n’oge na-adịghị mma, nke a nwere ike ibute mwepu, coma, na ọnwụ nke onye ọrịa.

Onye ọrịa ahụ kwesịrị ịgbanye ọgwụ insulin NPH ndị ọzọ ma ọ bụ ụdị ha naanị n'okpuru nlekọta dọkịta. Changgbanwe insulin na ọgwụ nwere ọrụ dị iche, usoro mmepụta (ntụgharị nke DNA, anụmanụ), ụdị (ezì, analog) nwere ike ịchọ ihe mberede ma ọ bụ, n'ụzọ megidere, mmezi dị mma nke usoro edepụtara.

Site na ọrịa nke akụrụ ma ọ bụ imeju, ọrụ pituitary na-ezughị ezu, ọrụ na-arụ ọrụ nke gland adrenal na thyroid gland, mkpa onye insulin nwere ike ibelata, yana oke nrụgide mmetụta uche na ụfọdụ ọnọdụ ndị ọzọ, na Kama nke ahụ, na-abawanye.

Onye ọrịa ahụ kwesịrị icheta oge ọ bụla na o nwere ike ịmalite hypoglycemia ma nyochaa nyocha nke ọma nke ahụ ya mgbe ọ na-anya ụgbọ ala ma ọ bụ mkpa ọrụ dị ize ndụ.

Monodar (K15, K30, K50),
Novomix 30 Flexspen,
Ryzodeg Flextach,
Humalog Mix (25, 50).
Gensulin M (10, 20, 30, 40, 50),
Gensulin N,
Rinsulin NPH,
Farmasulin H 30/70,
Humodar B,
Vosulin 30/70,
Vosulin N,
Mikstard 30 NM
Protafan NM,
Humulin.

Ime na lactation

Ọ bụrụ na nwanyị dị ime na-arịa ọrịa shuga, mgbe ahụ ọ dị mkpa karịsịa ka ọ chịkwaa glycemia. N'oge a, ịchọrọ insulin na-agbanwekarị n'oge dị iche iche. N'ime oge mbụ, ọ daa, na nke abụọ na nke atọ na-abawanye, yabụ idozi dose nwere ike ịdị mkpa.

Ọzọkwa, enwere ike ịgbanwe mgbanwe usoro onunu ogwu, nri na mmega ahụ n'oge a na-enye ara.

Ọ bụrụ na nhazi insulin a zuru oke maka onye ọrịa nwere ọrịa mellitus, yabụ nyocha banyere Humulin M3 na-abụkarị nke dị mma. Dabere na ndị ọrịa, ọgwụ a dị oke mma ma ihe fọrọ nke nta ka ọ nweghị mmetụta ọ bụla.

Ọ dị mkpa icheta na a machibidoro iwu ide insulin maka onwe gị, yana ịgbanwe ya ọzọ.

Otu karama Humulin M3 nwere olu nke 10 ml na-akwụ ụgwọ site na 500 ruo 600 rubles, ngwugwu nke katrized milimita atọ na ngụkọta nke 1000-1200 rubles.

Gịnị bụ pen sirinji

E chepụtara ha azụ na 1983, mana taa enwere ọtụtụ ụdị ụdị ngwaọrụ a. Na mkpokọta, mkpịsị ọ bụla bụ sirinji maka humulin ma ọ bụ mkpịsị sirinji maka biosulin yiri pen isi iyi (aha ahụ si na ya pụta) ma nwee mmemme ndị a:

Igbe - igbe yiri igbe dị na pen iyi,
Ulo na-emeghe ka ọ gafee n'otu akụkụ ma mechie akụkụ nke ọzọ. A na-etinye uwe aka jupụtara na insulin n'ime oghere a, n'aka nke ọzọ, o nwere bọtịnụ na-emechi emechi, yana usoro nke nwere ike ịtọ oke ahụ na ịpị: otu pịa - otu.
Ọkpụkpụ. Ha na-etinye ya n’ọnụ ọnụ aka ahụ tupu ịgba ya n’onwe ya. Aka uwe ahụ na-amụba site na oghere nke sirinji, mgbe emechara ntụtụ ahụ, a na-ewepụ agịga ahụ.
Ekpuchie nke etinyere na ngwaọrụ ebe anaghị eji ya. Mkpịsị sirinji dị iche na pen insulin n'ihi na enwere ike iji ya ọtụtụ oge yana ruo ọtụtụ afọ. Ma odi nfe iji:

Ikpe ahụ mepere, wepu ngwaọrụ ahụ, wepụ okpu ahụ na ya,
A na-etinye agịga ahụ, a na-ewepụkwa okpu ahụ na ya,
Ederede na-emegharị iji agwakọta insulin na uwe aka. You nwere ike tụgharịa ya ugboro iri na abụọ,
Nke mbu, edobere uzo abuo, a na-agbanye bọtịnụ eji egbochi ihe. Iji mee ka ikuku niile pụọ, tufuo insulin,
Ugbu a ka edobere ọgwụ achọrọ maka onye ọrịa ahụ, a gbanye ọgwụ mgbochi (ọ nwere ike ịbụ na afọ, ubu, ogwe aka ma ọ bụ ụkwụ). Ọ bụrụ na ọ dị mkpa, a na-eme ọgwụ ntụtụ ọbụna site na uwe, ihe kachasị bụ ịtọchi akpụkpọ ahụ,
Pịa bọtịnụ nkwụsị ahụ wee chere maka sekọnd ole na ole. Anyị ahapụla ịhapụ ụlọ ahụ ruo mgbe a gbanyere insulin niile,
Enwere ike wepu agịga ahụ, tinye okpu na ngwaọrụ ahụ ma zoo ihe niile dị na akpa ahụ.

Mkpịsị sirinji nwere uru na ọghọm ya.

Yabụ, usoro a dabara adaba: ka emechara, ị nwere ike tinye insulin na - ejighi akwa, na ụlọ akwụkwọ agụmakwụkwọ ma ọ bụ n'ebe ọrụ, agịga ya dị gịrịrị karịa ndị ọzọ na akpụkpọ adịghị emerụ ahụ ahụ ma ọlị.

Kwesịrị ekwesị maka ndị nwere nsogbu ọhụụ yana maka ndị nwere nkwarụ.

N’etiti adịghị ike bụ na mkpịsị mkpụrụ sirinji na-agbaji, ọ dịkwa njọ iji rụkwaa ya, n’ihi na emebi emebi usoro eji etinye usoro onodu ya nso.

Na mgbakwunye, ngwaọrụ a adịghị ọnụ ala, yana onye ọrịa chọrọ ihe dịka atọ n'ime ha, gụnyere otu maka ndochi na abụọ maka ndị ọrụ. Nke a bụ 150 maka oge niile. Syringes dị ọnụ ala. Ee, ị gaghịzikwa ụdị mkpịsị akwụkwọ a ebe niile.

Ma insulin na vials ka kariri insulin maka mkpịsị. Na mgbakwunye, ọtụtụ ndị na-emepụta na-emepụta mkpịsị akwụkwọ kpọmkwem maka insulin ha, yabụ ịtụtụrụ ya nwere ike isi ike.

Enwekwara mkpịsị mkpụrụ maka ọgwụ mgbochi ọgwụ intramuscular ngwa ngwa. Ọtụtụ mgbe ha na-eji ọgwụ mberede. Mgbe ụfọdụ a na-etinye ihe eji ede ihe n'ụdị ahụ ihe mberede. Ha dị mma na ha nwere ohere iji ya, a na-enyekwa ọgwụ ọgwụ naanị. Mwepu ya bu ihe atukwasighi ekwesi karia sirinji ot di na nnukwu ego.

Populardị ama ama nke edere edere

N'ezie, enwere ọtụtụ mkpịsị mkpụrụ sirinji, n'etiti ha, dịka ọmụmaatụ, enwere ndị nke ezubere naanị maka insulins site na ụfọdụ ndị nrụpụta, mana enwere ndị ghọrọ ewu ewu na latitude anyị.

Syringe pen biomatikpen. Ndị ụlọ ọrụ Switzerland bụ Ipsomed mepụtara. Nwere ihe ngosi kọmputa na njedebe. Ngosipụta na imewe dị mfe maka ịhọrọ usoro ziri ezi. Kwesịrị ekwesị maka biosulin (P ma ọ bụ H). Ogo kacha nari bu 60. Ọnụahịa - 2,5 puku rubles,
Syringe pen autofoam kpochapụwo. Ejiri ya na ihe nkwuputa ihe nkesa, yana mgbakwunye maka bọtịnụ mmalite. Dakọtara na agịga ọ bụla enwere ike iwepu, dị mma maka ụdị insulin dịka biosulin, rosinsulin, gensulin na Eli Lilly.Ihe bụ isi bụ na olu katrik ahụ ga-abụ mmelị 3. Enwerekwa mkpụrụ dị iche iche nke mkpụrụedemede dị otú a nke nwere mmụba na-abawanye na nkeji abụọ yana ọnụọgụ 42 kachasị.
Huma Pen Ergo. Nice pen sia mma maka humusulin sitere na Eli Lilly. Uzo ya di n’otu ihe eji eme ya, ihe eji eme ulo oru,
Syringe pen Novo Pen 3. Ngwaọrụ sitere na ndị Danish na-emepụta Novo Nordisk. O nwere igwe eji arụ ọrụ ma ọ dabara adaba maka insulins dịka Novomikst3, Protofan, Actrapid, Novorapid,
Opti Pen Pro 1. Mkpịsị odee French na onye nkesa ya n'ụdị ngosipụta elektrọnik. Ihe mgbawa ahụ bụ na batrị ya enweghị ike ịgbanwe agbanwe, yabụ ọ na-eje ozi naanị afọ abụọ,
Novo Pen Echo. Ntughari ohuru sitere na ndi otu ndi otu ndi Novo Nordisk. Ọ dị iche na obere usoro: 0,5. Adabara insulins nwere mkpokọta U100 nke ụdị ndị a: Protofan, Novoparid, Actapride, yana Novomikst3.

Ejiri ihe ngosipụta gosipụta ogo ikpeazụ insulin injection na mgbe etinyere ya. Mgbe etinyere ọgwụ dum, ngwaọrụ a na-eme oke ụda. Piston nwere ọrịa strok nke ukwuu, yabụ, nwatakịrị nwere ike iji ụdị ngwaọrụ a…

HumaPen Luxura HD. Ngwaọrụ ọzọ emere maka humulin. O nwere obere ukwu nke ọkara otu, dị na agba dị iche iche, ihe dịkarịsịrị mkpa bụ na mgbe a na-akpọ dose ahụ, mkpịsị akwụkwọ ahụ na-apụta ihe ngosipụta.

Mkpụrụ akwụkwọ sirinji maka insulin Humulin: gịnị bụ ya, ọnụahịa na nyocha

Ejiri insulin Humulin NPH mee ihe iji gwọọ ndị ọrịa nwere ọrịa shuga nke ụdị 1. Ndị ọrịa na-ata ahụhụ site n'eziokwu ahụ bụ na pancreas enweghị ike iwepụta insulin homonụ n'adabereghị.

Humulin bụ dochie anya insulin mmadụ. Ọtụtụ nyocha na-egosi ịdị irè nke ọgwụ a na nnabata ya dị mfe.

Ọnụahịa ọgwụ ahụ dịgasị n'etiti 1,500 rubles. Taa, ị nwekwara ike ịchọta ọtụtụ analogues nke ọgwụ ahụ, yana ọgwụ ọjọọ emekọrịta.

Ntuziaka maka iji ọgwụ ahụ

Ọ bụ dọkịta na-esonye ọgwụ nyere ọgwụ niile nke ọgwụ ahụ, dabere na njiri mara onye ọrịa ahụ na ọkwa glucose n'ọbara.

Humulin Humulin A na-atụ aro ka etinyere onye na-achịkwa ihe dị ka ọkara otu awa tupu isi nri ahụ, ebe ọnụ ọgụgụ kachasị mkpa nke ụbọchị ịgba ọkụ ekwesịghị ịgafe isii.

N'ọnọdụ ụfọdụ, a na-eme ọjeụ tupu ịmalite iri, kama mgbe otu elekere ma ọ bụ abụọ gasịrị.

Ekwesịrị itinyebata ọgwụ ọhụrụ ọ bụla n'ime ebe ọhụrụ iji zere ịmepụta lipodystrophy. Enwere ike ịchịkọta Onye na-ahụ maka ntanetị na subcutaneously, intramuscularly na ọbụna intravenously. Latterzọ nke abụọ na-abụkarị ndị dọkịta na-emekarị n'oge ịwa ahụ ma ọ bụ na-arịa ọrịa shuga n'ime onye ọrịa.

Na mgbakwunye, ọgwụ ahụ n'ọnọdụ ụfọdụ na ọgwụ ndị ọzọ na-eme ogologo oge.

Ọgwụ ndị ọgwụ chọrọ ọgwụ ndị ọgwụ chọrọ, ọ na-abụkarị nkeji iri atọ ruo iri anọ kwa ụbọchị.

Banyere ọgwụ insulin Humulin NPH, a machibidoro ya iwu inye ya ọgwụ mgbe ọ bụla. A na-emechi ma ọ bụ emulsion n'okpuru anụahụ ma ọ bụ, n'ọnọdụ ụfọdụ, intramuscularly.

Iji kpoo ogwu gị nke ọma, ị ga-achọ nkà ụfọdụ.

Algorithm maka nchịkwa insulin Humulin NPH

A ga-agwakọta Humulin na vials tupu a na-agwakọta vial n'etiti ọbụ aka ruo mgbe agba nke mmiri ara ehi pụtara. Emegharịla, ụfụfụ, ma ọ bụ jiri insulin nwere nsị na-acha uhie uhie na mgbidi nke vial ahụ.
Humulin NPH na katriiki abụghị naanị mpịakọta n'etiti nkwụ, na-emegharị mmegharị ahụ ugboro iri, kamakwa agwakọta, jiri nwayọ na-atụgharị katrij ahụ. Gbaa mbọ hụ na insulin dị njikere maka nchịkwa site na ịtụle agbanwe agbanwe na ụcha. E kwesịrị inwe otu ụdị nke ụcha n’ime mmiri ara ehi. Ọzọkwa atụpụkwala ma ọ bụ fụọ ọgwụ ọgwụ. Ejila okpomoku jiri ọka ma obu ahihia.Enweghi ike inyocha insulins ndị ọzọ na katriiki na enweghị ike jupụta.
Mkpịsị sirinji nwere milimita 3 nke insulin-isophan n ’ọgwụ nke 100 IU / ml. Maka ntụtụ 1, abanye karịa 60 IU. Ngwaọrụ na-enye ohere ka dosing jiri ezigbo ihe ruru 1 IU. Gbaa mbọ hụ na agịga ahụ dịgidesiri ike na ngwaọrụ ahụ.

- Jiri ncha sachaa aka, wee jiri ogwu na afere.

- Kpebie ebe a na-agba agba ma jiri akpụkpọ ahụ gwọọ ntutu.

- Ebe saịtị ịgba agba ọzọ ka agaghị eji otu ebe ahụ ihe karịa otu ugboro n'ọnwa.

Etu esi abanye ogwu?

Site na ntinye irighiri insulin n'okpuru anụ ahụ, ị kwesịrị ijide n'aka na agịga ahụ abanyeghị na ọbara ọbara, emekwala mmegharị ahụ ịhịa aka ozugbo tupu ịgba ntụtụ ahụ.

Taa, enwere ngwaọrụ pụrụ iche dị iche iche maka ịgbanye shuga, maka insulin. Ihe ndị a gụnyere katriji, mkpịsị sirinji, na sirinji insulin.

Tupu iji nkwusioru ya, a ga-afụcha ya n'ọbụ aka ka mmiri dị n'ime ampoule wee bụrụ otu. N'otu oge, ekwesịrị ịhapụ churning, nke na-enye aka na ụfụfụ.

Ọ bụrụ na-eji ọgwụ sirinji insulin, a ga-etinye dose nke dọkịta na-atụ aro ya ka ọ bụrụ nha 100 na 1 milliliter. Ugbo ala puru iche nwere ntuziaka nke aka ha ka ha jiri mee ihe, nke ikwesiri ibu uzo mara onwe gi. N'ime ya, dịka iwu, enwere ozi banyere otu esi ejikọ ọnụ ma dochie agịga kwesịrị ekwesị. Ọzọkwa, a na-ezube ụdị ngwaọrụ ndị ahụ maka naanị otu ugboro, a ga-egbochi ideju ha.

Enwere ike iji NPH mee ihe na Nhazi. N'okwu a, a ga-ebu ụzọ chịkọta insulin n'oge na-adịghị adị, ma gbatịkwuo. Mee nkuku jiri nlezianya mee ka ọgwụ abụọ ahụ ghara agwakọta.

Okwesiri iburu n’uche na otu ndi otu ogwu a nwere ike belata odi igba nke igba ogwu ndi mmadu:

Ogwu ogwula ogwu.
Corticosteroids.
Ọgwụ homonụ maka ọgwụgwọ nke ọrịa thyroid.
Typesfọdụ ụdị diuretics na ọgwụ mgbochi.

Ka iwelie mmetụta belata shuga, dịka:

Mbadamba hypoglycemic,
acetylsalicylic acid
mmanya na nkwadebe nwere ya.

Na mgbakwunye, sulfonamides na-enwe ike ịbawanye ike iwetulata shuga.

Kpachara anya maka ị .ụ ọgwụ

A na-enye mmetụta na-anọpụ iche nke ọgwụ ahụ na nsonaazụ ahụ ya naanị ma ọ bụrụ na agbasoro ndụmọdụ na ntụziaka nke dibịa na-aga.

Enwere oge ụfọdụ enwere ike ịme nsonaazụ ya.

Ihe na - eme ka nsonaazụ ndị ọzọ na - ejikọkarị na mmebi nke usoro ịgba ntụtụ ma ọ bụ mgbe ị gafere ogo ịchọrọ.

Ihe eji akpachapụ anya gụnyere ihe ndị a:

Hypoglycemia nwere ike ịmalite, ụdị siri ike nke na-ebute mmalite nke hypoglycemic coma. Onye ọrịa ahụ nwere ike ịda mbà n’obi na enweghị uche.
Mmepe nke mmeghachi omume nfụkasị ahụ, nke gosipụtara n'ụdị itching nke anụ ahụ, ọbara ọbara, ọzịza nke anụ ahụ. Ngosiputa oria a bu nwa oge, dika iwu, n’agha n’uzo nke ubochi.
Ọdịdị nke ahụrụ nke sistem. Mmeghachi omume ndị dị otú a na-etolite n'ụdị ihe isi ike na iku ume iku ume, obi mmadụ, na mbelata ọbara mgbali elu n'okpuru ụkpụrụ. Ntinye ume dị mkpụmkpụ na ọsụsọ na-apụta.

N’oge na-adịghị anya, enwere ike ịhụ lipodystrophy. Site na nyocha, ngosipụta dị otú ahụ na-adịghị mma nwere ike ịbụ naanị na nkwadebe nke si anụmanụ.

Ọgwụ bụ ike contraindicated:

n'ihu ọnụnọ hypoglycemia, ebe o nwere ikike iwetu glucose ọbara,
ọ bụrụ na achọtara hypers na otu ma ọ bụ karịa mmiri ọgwụ ahụ.

Ọgwụ a họọrọ nke ọma ma ọ bụ ịdoụbiga ihe ọdoụ canụ ókè nwere ike igosipụta onwe ya n'ụdị akara ndị a:

Nnukwu ọbara shuga dị n'okpuru ala.
Mmụba nke ụjọ ịma jijiji.
Isi ọwụwa.
Ugha na adighi ike nke aru.
Ọdịdị nke ọdịdọ.
Pallor nke anụ ahụ.
Ọdịdị nke ọsụsọ oyi.

Iji wepu ihe mgbaàmà ndị a dị n’elu, ị nwere ike iri nri nwere oke oke carbohydrates na -agaghị agbari. Ọ bụrụ n ’ịdoụbiga ọgwụ ike ókè, ị kwesịrị ịkpọtụrụ onye ọkachamara ahụike ozugbo.

Enwere ike iji ọgwụ ahụ n’oge ime ma ọ bụ na-enye nwa ara. Okwesiri iburu n’uzo na onwa ato mbu choro homonụ n’ime ụmụ nwanyị na-ebelata, mgbe nke a (n’ime nke abụọ na nke atọ) ọ na-abawanye.

Ọmụmụ ahụike gosipụtara na ịgbanye insulin anaghị enwe mmetụta mutagenic.

Njirimara nke itinye ngwa ngwaọrụ sirinji

Wepu okpu site na ị dọpụta ya kama ịtụgharị ya.
Lelee insulin, ndụ nchekwa, udidi na agba.
Jikere agịga dị ka akọwara n’elu.
Ghaa agịga ahụ ruo mgbe o siri ike.
Wepu akwa abụọ site na agịga Akwụpụla isi okpu.
Lelee oriri insulin.
Mechie akpụkpọ ahụ ma gbanye agịga n'okpuru anụ ahụ na akụkụ 45.
Iwebata insulin site na ijide mkpịsị aka gị na mkpịsị aka gị ruo mgbe ọ kwụsịrị, na-eji nwayọ gụọ 5.
Mgbe i wepụsịrị agịga ahụ, tinye bọl mmanya na-egbu egbu na ebe ntụtụ ahụ na-enweghị nhichapụ ma ọ bụ na-egwepịa anụ ahụ. Dị ka ọ na-adịkarị, dobe insulin nwere ike ịnọrọ n'ọnụ ọnụ agịga ahụ, mana ọ bụghị isi na ya wụpụta, nke pụtara oke ezughị ezu.
Jiri okpu aka mechie agịga ma wepụ ya.

O nwere ike imekorita ya na ọgwụ ndi ozo

Ọgwụ ndị na-akwalite nsonaazụ Humulin:

Mbadamba mbadamba shuga,
antidepressants - monoamine oxidase inhibitors,
ọgwụ hypotonic sitere na otu ACE inhibitors na beta blockers,
carbonic anhydrase inhibitors,
imidazoles
ọgwụ mgbochi ọrịa tetracycline,
nkwadebe lithium
B vitamin,
theophylline
ọgwụ ọjọọ nwere mmanya.

Ọgwụ na-egbochi imepụta insulin Humulin NPH:

ọgwụ mgbochi ịmụ nwa
glucocorticosteroids,
homonụ thyroid
diuretics
tricyclic antidepressants,
ndị na-arụ ọrụ na-eme ka ọmịiko na-eme ebere,
ihe ngbanwe calcium
ọgwụ ọgwụ ọjọọ.

Analogs nke Humulin

Aha ahia	Emeputa
Insuman Bazal	Sanofi-Aventis Deutschland GmbH, (Germany)
Protafan	Novo Nordisk A / S, (Denmark)
Berlinsulin N Basal U-40 na Berlisulin N Basal Pen	Berlin-Chemie AG, (Germany)
Actrafan HM	Novo Nordisk A / O, (Denmark)
Br-Insulmidi ChSP	Bryntsalov-A, (Russia)
Humodar B	Indar insulin CJSC, (Ukraine)
Isofan Insulin anwụ Monde	AI CN Galenika, (Yugoslavia)
Homofan	Pliva, (Croatia)
Biogulin NPH	Bioroba SA, (Brazil)

Nyochaa ọgwụ ọgwụ na-egbochi insulin-isophan:

Achọrọ m ịme mgbazi - a machibidoro ịnye insulin ogologo oge!

Pharmacodynamics na pharmacokinetics

Humulin NPH bụ Ihe nnabata DNA na - eme mmadụ insulin ya na oge iji gosipụta mkparịta ụka, isi ihe dị na ya bụ ịhazi ihe glucose metabolism. Ọgwụ na-egosikwa anabolic arụmọrụ.

N'ime anụ ahụ nke mmadụ (ewezuga akwara ụbụrụ), insulin Humulin NPH na-eme ka ebugharị ebugharị amino acid na glucose, na-emekwa ka usoro ya dị ngwa anabolism protein.

Yiri na imeju, ọgwụ na-akwalite nguzobe nke glycogen site na glucosena-akpali mgbanwe nke njuputa glucose n'ime abụbamgbochi gluconeogenesis.

A na - ahụta mmalite nke insulin Humulin NPH nkeji 60 mgbe nlekọta nchịkwa, na arụmọrụ kachasị na oge ahụ site na awa 2 ruo 8 na oge nke ime n'ime awa 18-20.

Hụrụ onye iche na arụmọrụ insulin dabere na nhọrọ ị doseụ ọgwụ, saịtị ịgba ọgwụ, yana ọrụ anụ ahụ nke onye ọrịa.

Nsonaazụ

Mmetụta dị n'akụkụ bụ hypoglycemia, nke n’ihe banyere oke ọrụ nwere ike ibute nsụhọ na ọbụna ọnwụ (adịkarịghị).

Enwekwara ike di otua lipodystrophy.

Ihe ngosipụta anwansị nke ụdị systemic:

Ihe ngosipụta anwansị nke ọdịdị mpaghara:

ọzịza ma obu itching na mpaghara ịgba ogwu (na-akwụsịkarị n'ime izu ole na ole),
hyperemia.

Ntuziaka maka iji Humulin NPH

A họrọ usoro ọgwụ Humulin NPH n'otu n'otu, dabere na ọkwa nke glycemia onye ọrịa.

Amachibidoro inje intulin nke Humulin NPH!

Ekwesịrị iji aka emulsion ahụ mee, mgbe ụfọdụ, a na-ahapụ inje IM. A na-eme nchịkwa subcutaneous n'ime afọ, ubu, ike ma ọ bụ apata ụkwụ. Ekwesịrị ịgbanwere ebe a ga-agba ntụtụ ka ụbọchị iri atọ ọ bụla agaghị agbafe otu ebe.

Ntugharị SC chọrọ ụfọdụ ọrụ maka njikwa na ịkpachara anya. Ọ dị mkpa izere ịbanye na agịga n'ime arịa ọbara, ọ bụghị ịhịa aka n'ahụ ebe a na-agba ya, yana ijikwa ngwaọrụ ndị na-eji ọgwụ ahụ nke ọma.

Nkwadebe na nhazi nke Humulin NPH

Na ebumnuche nnweta insulin, tupu iji ya, a na-atụ aro vials na katridges nke Humulin NPH ịkwado ugboro 10 n'ọbụ aka gị ma maa jijiji otu oge ugboro (tụgharịa 180 Celsius) ruo mgbe nkwadebe ahụ ga-enweta ọnọdụ nke agba mara mma na mmiri ara ehi ma ọ bụ mmiri na-agakọ. Kingkagbu ọgwụ ahụ ike ekwesịghị ịdị, ebe ọ bụ na ụfụfụ guzobere n'ụzọ a nwere ike igbochi kpọmkwem nhọrọ nke dose ahụ.

A ga-eji nlezianya nyochaa vials na katriji. Zere iji insulin eji ogwe osisi na-acha uhie uhie ma ọ bụ nke na-acha ọcha na-agbada na mgbidi ma ọ bụ ala nke kalama ahụ, na-eme ka echiche nke usoro ntu oyi.

Ihe okike n’aputa ihe anaghi eme ka ihe ya di nma na ndi ozo insulin, yana ị na-emejupụta katọn ahụ n'onwe ya.

Mgbe ị na-eji vials, a na-anakọta emulsion na nke ahụ sirinji insulin, nke na olu kwekọrọ na ntinye insulin (dịka 100 IU / 1 ml insulin = Sirinji 1 ml) ma jikwa ya na ntinye nke dọkịta.

Mgbe ị na-eji katriji dị iche iche, ọ dị mkpa ịgbaso ndụmọdụ nke onye mepụtara sirinji mkpịsị maka ịwụnye ha, na-ejide agịga, ma na-achịkwa insulin, dịka ọmụmaatụ, ntuziaka maka Humulin NPH na mkpịsị Pen Pen Ndenye.

Ngwa ngwa ozugbo, iji mpụta nke agịga, wepụ agịga ahụ n'onwe ya ma bibie ya n'ụzọ adịghị mma, wee jiri okpu ahụ mechie aka ahụ. Usoro a na-enyekwu ikike, na-egbochi ikuku ịbanye, na-egbochi ịhapụ ọgwụ ahụ na ịhapụ ịlogụ ọgwụ ọ bụla.

Ekwesighi iji ndị ọzọ mee ihe ma ọ bụ jiri mkpịsị mkpụrụ osisi sirinji. A na-eji vials na katridges otu oge ruo mgbe ọgwụ a gwụchara, wee tụfuo.

Ikekwe iwebata Humulin NPH yana Humulin Regular.

Maka gịnị, iji gbochie ịbanye na karama ahụ insulin ime ihe dị ogologo, onye izizi ị banye na sirinji insulin obere ihe.

A na-atụ aro ka ịmebata ngwakọta a ozugbo agwakọta. Maka ezigbo usoro ọgwụgwọ abụọ insulin nwere ike iji sirinji dị iche iche.

Mmekorita

Podị Hypoglycemic nke Humulin NPH na-ebelata site na iji concomitant ọgwụ mgbochihomonụ thyroid glucocorticoids, thiazide diureticstricyclic antidepressants, Diazoxide.

Ngwa ijikọtara ethanolọgwụ hypoglycemic (onu), salicylatesMA inhibitors sulfonamides, ihe mgbochi beta welie mmetụta hypoglycemic nke Humulin NPH.

Ihe ndozi, Clonidine na ihe mgbochi beta nwere ike ime ka mgbaàmà hypoglycemia pụta.

N’ime ime (ma lactation)

Ndị ọrịa nwere ọrịa shuga gwa onye nlekọta ahụike gbasara ịme atụmatụ ma ọ bụ ihe omume nke afọ ime, dị ka ọ dị na mbụ, mkpa maka insulin na-agbadata na ọkara nke mbụ ma na-abawanye na ọkara nke abụọ na nke atọ (agba agba nwere ike ịdị mkpa insulin na idozi uzo ozo).

Ọzọkwa, enwere ike ịchọ nhazi nri na / ma ọ bụ dozie oge a lactation.

Mgbe ị na-ahọrọ insulin dọkịta ga-elele ọnọdụ onye ọrịa ahụ n'akụkụ niile enwere ike ịhọrọ ọgwụ dabara adaba maka ndị ọrịa a.

N'okwu a, ọgwụ Humulin NPH na-egosi nsonaazụ ọgwụgwọ dị mma ma enwere ike iji ya were ogologo oge.

Humulin NPH dị ọnụ, ebe ị ga-azụ

You nwere ike ịzụta Humulin NPH na nkezi: karama nke 10 ml Nke 1 - 550 rubles, 3 ml cartridges Nke 5 - 1500 rubles.

Humulin NPH nkwusioru 100 IU / ml 10 ml Lilly Eli Lilly & .lọ ọrụ
Humulin NPH nkwusioru 100 IU / ml 3 ml 5 PC.

Humulin NPH nkwusioru 100ME / ml 3ml Nke 5 katrized + QuickPenEli Lilly & sirinji ụlọ ọrụ
Humulin NPH nkwusioru 100ME / ml 3ml Nke 5 katridgesEli Lilly & Company
Humulin NPH nkwusioru 100MU / ml 10ml Nke 1 botEli Lilly & Company

Kwụsị uche! Ihe omuma banyere ogwu nke saịtị a bu ihe banyere nbuso-agha, anakpo ya site n public isi obodo ma na enweghi ike ibu ihe ndabere iji kpebie etu ogwu si di. Tupu ị Humụ ọgwụ Humulin NPH, jide n'aka ịkpọ dọkịta gị.

Zụta n'ime ụlọ ahịa anyị nke nwere mkpịsị mkpịsị mkpụrụ osisi HumaPen Luxura - DiaMarka

Iyi mkpịsị ugodi adaba na arụ ọrụ HumaPen Luxura nwere usoro nke 1. Mkpịsị mkpụrụ ndụ Eli Lilly sịnịma (Eli Lilly) nwere krim 3 ml. Aka ahụ nwere ọdịdị mara mma mara mma, nwere ihe ntinye chrome.

Ọ nwere ike ịghọ ọ bụghị naanị ụzọ iji megwara ọrịa shuga, kamakwa ọ bụ ezigbo ịchọ mma ma ọ bụrụ na itinye ya n’akpa uwe elu ma ọ bụ jaket gị. Ọnọdụ siri ike na nke na-adịgide adịgide na-echebe mkpịsị sirinji ahụ ka ọ ghara imebi, ọbụlagodi ma ọ bụrụ na ị tufue ya n’ala.

Mmụba a na-etinye na ya bụ 1.

Ejiri pen Lilly mepụta sirinji ma dabara adaba maka ihe mkpuchi niile nke onye nrụpụta a:

Ntị! HumaPen Luxura Syringe Pen dabara maka insulin biosulin. Ọnụ ego nke mkpụrụ sirinji a maka Biosulin nwere ezi uche.

Ọzọkwa, n'ihe egwu na nsogbu gị, ịnwere ike iji mkpịsị akwụkwọ a mee insulin ”na Apidra.
Nka nka na ụzụ Syringe pensụl HumaPen Luxura

Ezubere maka penphles 3 ml (nkeji 300).
Nzọụkwụ kacha nta bụ setịpụrụ insulin nke 1 otu.
Oke kachasị na otu setị bụ 60 nkeji.
Akụkụ: 165x25x23 mm
Ibu ibu: 30 g.

Njirimara nke syringe pen HumaPen Luxura:

Njikwa nlezi anya na ụda mgbe ị na-ede ihe nke insulin
Ike ịkagbu dose ahụ
Magburu onwe ya mma "n'ọgbakọ
Ọdịdị mara mma na nke mara mma
Dị mma, akwa ike siri ike na-agbakwunye ahụ onwe ya.

Humapen Luxura Syringe Pen
Ikpe (enwere ebe maka akpa agịga na insulin klọọkụ)
Ntuziaka na Russian

HumaPen Luxura Syringe Pen Gbaara akaebe maka ire ere na Russia. Ihe osise ngwaahịa, gụnyere agba, nwere ike ịdị iche na ọdịdị ahụ. Ihe ngwugwu a dịkwa na-agbanwe agbanwe n’enweghị ọkwa. Nkọwa a abụghị onyinye ọha na eze.

HumaPen Luxura Syringe Pen - ọnụahịa 2150,00 rub., Foto, nkọwa teknụzụ, ọnọdụ nnyefe na Russia. Buyzụta HumaPen Luxura Syringe Pen n'ụlọ ahịa dị n'ịntanetị https: diamarka.com, dị nnọọ jupụta ụdị ntanetị iji kpọọ ma ọ bụ kpọọ: +7 (3452) 542-147, +7 (922) 483-55-85.

Humulin: ntuziaka maka ojiji, ọnụahịa, nyocha na analogues

Preparationkwadebe insulin kwesịrị inwe obere ọgwụ mgbochi na mmetụta ọ na-akpata, n'ihi na ndị na-arịa ọrịa shuga amalitelarị ịrịa ọtụtụ ọrịa concomitant. Ọgwụ a dịkwa iche na analogues n'ọtụtụ ụzọ, gụnyere ihe ndị dị na ya. Tụlee ihe kpatara Humulin NPH ji dị mma maka ọrịa shuga dabere na ntuziaka maka ojiji.

Ndị na-emepụta INN

Aha mba ụwa bụ insulin-isophan (inyocha mkpụrụ ndụ mmadụ).

Ọ bụ Lilly France S.A.S., France ka mepụtara ya.

Onye nnọchi anya Russia: “Eli Lilly Vostok S.A.”

“Humulin” dịgasị na ọnụahịa dabere n'ụdị ntọhapụ: karama sitere na 300-500 rubles, katriki si 800-1000 rubles. Ọnụ ego ahụ nwere ike ịdị iche iche n’obodo dị iche iche na ụlọ ahịa ọgwụ.

Omume ọgwụ