Thioctacid 600 t: ntuziaka maka ojiji

1 ampoule nke ihe ngwọta nwere:

Ihe na-arụ ọrụ: 952.3 mg nke trometamol nnu nke thioctic acid (na usoro nke thioctic (a-lipoic acid) - 600.0 mg).

Ndị ọkachamara: trometamol, mmiri maka injection.

Mpempe ọnya edo edo.

Omume ọgwụ

Alpha-lipoic (thioctic) acid bụ ihe vitamin dị ka ihe nwere coenzyme. A kpụrụ ya n’ime ahụ n’oge nri oxidative decarboxylation nke alpha-keto acid.

Na ọrịa shuga mellitus n'ihi hyperglycemia, ọdịnaya nke ngwaahịa glycosylation ikpeazụ na-abawanye. Usoro a na - eduga n'ịbelata ọbara ọbara endoneural na mmepe nke hypoxia endoneural. N'otu oge ahụ, yana mmụba na nguzobe nke radicals n'efu, ọdịnaya nke antioxidants, karịchaa, glutathione, na-ebelata.

Alpha-lipoic (thioctic) acid bụ ihe vitamin dị ka ihe nwere coenzyme. N'ime ahụ, a na-akpụ ya n'oge decarboxylation nke oxidative nke alpha-keto acid.

Na ọrịa shuga mellitus n'ihi hyperglycemia, ọdịnaya nke ngwaahịa glycosylation ikpeazụ na-abawanye. Usoro a na - eduga n'ịbelata ọbara ọbara endoneural na mmepe nke hypoxia endoneural. N'otu oge ahụ, yana mmụba na nguzobe nke radicals n'efu, ọdịnaya nke antioxidants, karịchaa, glutathione, na-ebelata.

Na nyocha nnwale na oke, emere ka ọ gosipụta na alfa-lipoic acid na -ebelata nguzobe nke ngwaahịa glycosylation, na-eme ka ọbara na-erugharị ma na-abawanye ọkwa glutathione. Ihe omuma ndi a na-enye echiche na alfa lipoic acid nwere ike itinye aka na ndozi akwara akwara. Nke a metụtara nsogbu sensọ na polyneuropathy na-arịa ọrịa shuga, dịka dysesthesia, paresthesia (ọkụ, ihe mgbu, ọnya, tingling). N'ime ule ụlọ ọgwụ na ndị ọrịa nwere polyneuropathy na-arịa ọrịa shuga, nchịkwa nke alfa-lipoic acid emeela ka mbelata nkwarụ uche na-eso polyneuropathy mamịrị (mgbu, paresthesia, dysesthesia, ọnụọgụ).

Ime na lactation

Enwere data dị na nsonaazụ toxicological na ịmụpụta adịghị enye ohere ị nweta nkwubi okwu banyere nsogbu na-emerụ ahụ nwa ebu n'afọ. N'ihi ụkọ data ezughị ezu, a naghị atụ aro ọgwụ ahụ maka ụmụ nwanyị n'oge afọ ime.

Amabeghị ma acid thioctic (a-lipoic) na-abanye na mmiri ara. Ọ bụrụ na ọ dị mkpa iji ọgwụ mee ihe n’oge ị na-enye nwa ara, a ga-akwụsị inye ya ara.

Usoro onunu ogwu na nhazi

Ọgwụ kwa ụbọchị na mmalite ọgwụgwọ maka nsogbu uche dị ukwuu na polyneuropathy na-arịa ọrịa shuga bụ 1 ampoule nke Thioctacid 600 T (nke kwekọrọ na 600 mg nke thioctic acid) maka izu 2-4.

Enwere ike iji Thioctacid 600 T dị ka infusion na isotonic sodium chloride solution (infusion olu 100-250 ml) maka minit 30. Ekwesịrị iji nwayọ rụọ ọrụ nwayọ (ọbụghị ọsọ ọsọ karịa 50 mg nke thioctic acid, dịka 2 ml nke ihe ngwọta nke Thioctacid 600 T kwa nkeji). Na mgbakwunye, ọgwụgwọ intravenous nke agbanwe agbanwe na-agwọ ọrịa sirinji ma ọ bụ onye na-ekpochapụ. N'okwu a, oge nchịkwa kwesịrị ịbụ opekata mpe nkeji iri na abụọ.

Usoro ntụpọ

N'ihi nnabata nke ihe na-arụ ọrụ n’ọkụ, ekwesịrị iwepụ ampoules na kaadiboodu naanị ozugbo tupu ejiri ya. N'ụdị ihe mgbaze maka nsogbu infusion nke Thioctacid 600 T, jiri naanị isotonic sodium chloride solution. Ekwesịrị idobe ihe mgbochi infusion site na ọkụ (dịka ọmụmaatụ, na foil aluminom). Ngwọta maka infusion, nke a na-echebe site na ìhè, kwesịrị ekwesị maka awa 6.

Na-esote, ha na-agagharị na usoro ọgwụgwọ mmezi site na iji usoro on-lipoic acid maka nchịkwa ọnụ na dose nke 300-600 mg kwa ụbọchị.

Ihe ndabere maka ọgwụgwọ polyneuropathy na-arịa ọrịa shuga bụ ezigbo ọgwụgwọ maka ọrịa shuga.

Dodoụbiga ya ókè

Ọ bụrụ n ’ịdoụbiga mmanya ókè, ọgbụgbọ, ọgbụgbọ, na isi ọwụwa nwere ike ibilite. Mgbe ị alụ ọgwụ alpha-lipoic mechara n ’ịalụ mmanya na-egbu ihe dị ka 10 ruo 40 g, axụrụma dị ukwuu, mgbe ụfọdụ, ọ na-arụpụta ihe na-akpata ya. Ihe mgbaàmà nke egbu egbu nwere ike ibu ụzọ gosipụta ụdị mkpamkpa uche uche ma ọ bụ ọgba aghara, n'ọdịniihu ha na-ejikarị ihe ọdịdọ na mmepe nke lactic acidosis. Na mgbakwunye, n'ihi mmụba na oke nke alfa-lipoic acid, hypoglycemia, ujo, rhabdomyolysis, hemolysis, disselation intravascular coagulation (DIC), mwepu nke ụmị ọkpụkpụ na ọtụtụ otutu akụkụ ọdịda.

Ọbụna na obere enyo enyo na-egbu egbu, Thioctacid na-egosi ụlọ ọgwụ ozugbo na usoro ọgwụgwọ izugbe maka nkwụsị. Na usoro ọgwụgwọ ihe ọdịdọ juru, lactic acidosis na nsogbu ndị ọzọ na-eyi ndụ egwu nke ịxụbiga mmanya ókè, ọ dị mkpa ịgwọ ọrịa Symptomatic. Ruo ugbu a, ekwenyeghị ịdị irè nke hemodialysis na ụzọ igbu ọrịa extracorporeal iji mee ka mkpụrụ nke alfa-lipoic acid dị ngwa.

Mmekọrịta na ọgwụ ndị ọzọ

Site na nhazi nke Thioctacid 600 T, a na-achọpụta mbelata nke arụmọrụ nke cisplatin. Thioctacid 600 T na-ejikọ ọla ahụ na nkwadebe nwere ọla (dịka ọmụmaatụ, iron, magnesium, ngwaahịa mmiri ara ehi nwere calcium).

Iji otu oge, enwere ike ịkwalite mmetụta na-ebelata shuga nke insulin na ọgwụ antidiedi maka nchịkwa ọnụ, ya mere, a na-atụ aro maka itinye glucose ọbara n'ọtụtụ oge, karịsịa na mmalite ọgwụgwọ na Thioctacid 600 T. n’ime ọbara).

Alfa lipoic acid na-emeghachi na vitro nwere ogige ọla ionic (dịka, cisplatin). Alfa-lipoic acid na-akpụkọ ụmụ irighiri mmiri na-emezighị emezi. Thioctacid 600 T ekwekọghị na ngwọta dextrose, Ngwọta Ringer, yana ihe ngwọta na-emeghachi na ìgwè disulfide ma ọ bụ SH.

Dịka ihe mgbaze maka ọgwụ Thioctacid 600 T, enwere ike iji sodium chloride sọdum isotonic sodium.

Nchedo nchekwa

Alcoholụ mmanya na-aga n'ihu bụ ihe dị ize ndụ maka mmepe nke polyneuropathy ma nwee ike belata arụmọrụ nke Thioctacid 600 T. Ya mere, a na-adụ ndị ọrịa ọdụ ka ha ghara ị takingụ mmanya na-aba n'anya ma n'oge ị withụ ọgwụ na n'oge oge na-abụghị ọgwụgwọ.

Site na nhazi nke intravenic nke a-lipoic acid, a na-edekọ mmeghachi omume hyperensitivity, gụnyere anaphylactic shock (lee mpaghara “Side side”). N'oge ọgwụgwọ, nyocha onye ọrịa mgbe niile dị mkpa. N'ihe banyere mgbaàmà (dịka ọmụmaatụ, itching, ọgbụgbọ, malaise, wdg), ịkwesịrị ịkwụsị nchịkwa nke ọgwụ ahụ ozugbo ekwesịrị ịnye ọgwụ ndị ọzọ ma ọ bụrụ na ọ dị mkpa.

Mgbe etinyere ọgwụ Thioctacid 600 T, mgbanwe nke isi mmamịrị ga-ekwe omume, nke na-enweghị ihe ọhụụ.