Thiogamma analogues
Thiogamma bụ ọgwụ antioxidant na metabolic ọgwụ nke na-edozi carbohydrate na metabolism metabolism.
Ihe na-arụ ọrụ nke ọgwụ ahụ bụ acid thioctic (alpha-lipoic) acid. Ọ bụ antioxidant endogenous na-ejikọ radicals n'efu. A na-etolite Thioctic acid n’ahụ n’ime oge oxidative decarboxylation nke alpha-keto acid.
Acid Thioctic na-edozi carbohydrate na lipid metabolism, na-eme ka ọrụ imeju na-akpali metabolism metabolism. O nwere hypoliplera, hypoglycemic, hepatoprotective na mmetụta hypocholesterolemic. Na-akwalite ahụike oriri nke neurons.
Alfa-lipoic acid na-enyere aka belata glucose ọbara, mee ka mkpokọta glycogen nwee umeji ma merie nguzogide insulin. Site na usoro nke ime ihe, ọ dị nso na vitamin nke otu B.
Mmụta banyere oke na-arịa ọrịa shuga na-akpata streptozotocin egosiwo na thioctic acid na-ebelata nguzobe nke ngwaahịa glycation, na-eme ka ọbara na-abanye ngwa ngwa, ma na-abawanye ọkwa nke ọgwụ na-egbochi ihe dị ka glutathione. Ihe akaebe gosipụtara na thioctic acid na-eme ka ọrụ neuron dịpụrụ adịpụ.
Nke a metụtara nsogbu sensọ na polyneuropathy na-arịa ọrịa shuga, dịka dysesthesia, paresthesia (ọkụ, ihe mgbu, mkpọda, belatara). Ekwuputara nsonaazụ ndị a site na nnwale ụlọ ọgwụ multicenter emere na 1995.
Ofdị maka ịhapụ ọgwụ ahụ:
- Mbadamba ụrọ - 600 mg nke arụmọrụ n'ime nke ọ bụla,
- Ngwọta maka nchịkwa parenteral nke 3%, ampoules nke 20 ml (na 1 ampoule 600 mg nke ihe na-arụ ọrụ),
- Thiogamma-turbo - ihe ngwọta maka infrenteral infusion 1.2%, 50 ml vials (na 1 karama 600 mg nke ihe na-arụ ọrụ).
Ihe ngosi maka ojiji
Gịnị na-enyere Tiogamma aka? Kọwaa ọgwụ ahụ n'ọnọdụ ndị a:
- Ọrịa imeju na abụba (ọrịa imeju na-egbu egbu),
- Hyperlipidemia nke amaghi (ezigbo abụba)
- Legwakọta na-egbu egbu na-egbu egbu (imebi akpịrị na-egbu egbu)
- Imeju imeju
- Ọrịa kansa na-egbu egbu na nsonaazụ ya,
- Ọrịa ịba ọcha n'anya nke agbụrụ ọ bụla,
- Ọrịa ịba ọcha n'anya,
- Cirrhosis nke imeju.
Ntụziaka maka iji Thiogamma, usoro onunu ogwu
Ana mburu mbadamba nkume ndị ahụ ọnụ, na afọ na-enweghị ihe ọ amountụ ,ụ, jiri obere mmiri hichaa ya.
Usoro a tụrụ aro bụ 1 mbadamba Tiogamma 600 mg 1 oge kwa ụbọchị. Ogologo oge nke ọgwụgwọ na-adabere n'ịdị ogo ọrịa ahụ na-esite na ụbọchị 30 ruo 60.
N’afọ, a ga-emeghachi ọgwụgwọ ahụ ugboro abụọ.
Inje
A na-achịkwa ọgwụ ahụ na iv na dose nke 600 mg / ụbọchị (1 ngbanye uche maka nkwadebe nke ihe ngwọta maka infusion nke 30 mg / ml ma ọ bụ karama 1 nke ihe ngwọta maka infusion nke 12 mg / ml).
Na nmalite usoro ọgwụgwọ, a na-atụ aro ka a nye ya iv maka izu 2-4. Mgbe ahụ ị nwere ike ịga n’ihu ị takingụ ọgwụ ahụ n’ime ntakịrị nke 300-600 mg / ụbọchị.
Mgbe ị na-etinye ọgwụ mgbochi intravenous, ekwesịrị ịnye ọgwụ ahụ nwayọ nwayọ, na ọnụego nke na-erughị 50 mg / min (nke ya na 1.7 ml nke itinye uche maka nkwadebe nke ihe ngwọta maka infusion nke 30 mg / ml).
Kwadebe ihe ngwakọ - a ga-agwakọta ọdịnaya nke otu ampoule nke itinye aka na 50-250 ml nke slorum chloride 0.9%. E kpuchie karama ahụ na ihe ejikere ka ọ bụrụ nke nwere ihe mkpuchi ọkụ, nke na-abịazu n’ọgwụ ahụ. Enwere ike ịchekwa ngwọta dị njikere karịa awa 6.
Ọ bụrụ na-eji ọgwụ infusion dị njikere mee, a na-ewepụ karama ọgwụ ahụ n'igbe wee kpuchie ya ngwa ngwa na-ekpuchi ọkụ. A na-ewebata mmeghe ahụ site na karama ahụ, jiri nwayọ - na ọsọ nke 1.7 ml / nkeji.
Nsonaazụ
Enwere ike ijikọ Thiogamma na nsonaazụ ndị a:
Site na usoro digestive: mgbe ị na-a theụ ọgwụ n'ime - dyspepsia (gụnyere ọgbụgbọ, vomiting, obi mgbawa).
- Site n'akụkụ nke usoro ụjọ ahụ: ọ na - adịkarị (mgbe nchịkwa iv) - nkwarụ, diplopia, na nchịkwa ngwa ngwa - ịba ụba intracranial (ọdịdị nke mmetụta nke ibu na isi).
- Site na usoro coagulation ọbara: adịkarịsịrị (mgbe nchịkwa iv) gasịrị - ọnụego ọbara na akpụkpọ ahụ, akpụkpọ ahụ, thrombocytopenia, ọrịa mbufụt (purpura), thrombophlebitis.
- Site na usoro iku ume: ya na ngwangwa / na ntinye okwu, iku ume siri ike omume.
- Mmeghachi omume nfụkasị: urticaria, mmeghachi omume sistemụ (ruo n'ọzụ nke anaphylactic ujo).
- Ndị ọzọ: hypoglycemia nwere ike ịmalite (n'ihi mmụba glucose dị mma).
Ihe ngbanwe
Thiogamma na-contraindicated na ndị a:
- ụmụaka na ndị na-eto eto nọ n’agbata afọ 18,
- oge ime
- oge lactation
- glucose-galactose malabsorption, ụkọ lactase, enweghị nkwekọrịta galactose (maka mbadamba),
- hypersensitivity na isi ma ọ bụ inyeaka ọgwụ nke ọgwụ.
Na nzụlite nke iji ọgwụ ọjọọ eme ihe, a pụghị ị alcoholụ mmanya na-egbu egbu, ebe ọ bụ na n'okpuru nduzi nke ethanol, enwere ike nke ịmalite nsogbu siri ike site na sistem ụjọ na akwara nri.
Anaakpọ Thiogamma, ọnụahịa dị na ahịa ọgwụ
Ọ bụrụ na ọ dị mkpa, ịnwere iji dochie iji Thiogamma dochie ihe arụ ọrụ - ndị a bụ ọgwụ ọjọọ:
Mgbe ị na-ahọrọ analogues, ọ dị mkpa ịghọta na ntuziaka maka iji Tiogamma, ọnụahịa na nyocha nke ọgwụ nwere mmetụta ndị yiri ya anaghị emetụta. Ọ dị mkpa ịnweta ndụmọdụ nke dọkịta na ịghara ime mgbanwe ọgwụ ọ bụla.
Ahịa ahịa na ọgwụ ọgwụ Moscow: ngwọta Thiogamma 12 mg / ml 50 ml - site na 197 ruo 209 rubles. Mpempe 600 mg 30 pcs. - site na 793 ruo 863 rubles.
Debe isi ebe ụmụaka nọ, na-echebe ya site n'ọkụ, na-ekpo ọkụ ruo 25 Celsius. Ndụ shelf bụ afọ 5. N’ebe a na-ere ọgwụ, ọgwụ dị.
Nyocha 3 maka “Tiogamma”
Ọ na-enyere ọtụtụ aka. Mama m na-a drugụ ọgwụ a ugboro abụọ n’afọ. Mgbe o jesịrị ya, ọ na-enwe mmetụta dị mma karị!
Enyere m otu mpekere nwere nsogbu nke elekere na elekere 14.00 nke ehihie, na elekere 24,00 n'abalị mgbali ahụ rutere 177 site na 120. Isi m merụrụ m nnukwu, echere m na ọ ga-agbada. Otuodi wetara nrụgide nke Christifar na Kapoten. Achọpụtara m na ụdị mmeghachi omume a nke tiagammu 🙁
Onye dibia bekee nyere nwa ya nwoke acid ihe eji eme ihe, ma obughi ogwu a.
Analogs na ihe mejupụtara ma gosipụta maka ojiji
| Aha | Ọnụahịa na Russia | Ọnụahịa na Ukraine |
|---|---|---|
| Alfa lipon alfa lipoic acid | -- | 51 UAH |
| Berlition 300 Oral | -- | 272 UAH |
| Berlition 300 thioctic acid | 260 nkp | 66 UAH |
| Dialipon thioctic acid | -- | 26 UAH |
| Espa lipon thioctic acid | 27 nkp | 29 UAH |
| Espa lipon 600 thioctic acid | -- | 255 UAH |
| Alfa Lipoic Acid Alfa Lipoic Acid | 165 rub | 235 UAH |
| Oktolipen | 285 nkp | 360 UAH |
| Berlition 600 thioctic acid | 755 rub | 14 UAH |
| Dialipon Turbo thioctic acid | -- | 45 UAH |
| Tio-Lipon - Novopharm thioctic acid | -- | -- |
| Thiogamma Turbo thioctic acid | -- | 103 UAH |
| Thioctacid thioctic acid | 37 nkp | 119 UAH |
| Thiolept thioctic acid | 7 nkp | 700 UAH |
| Thioctacid BV thioctic acid | 113 rub | -- |
| Thiolipone thioctic acid | 306 rub | 246 UAH |
| Altiox thioctic acid | -- | -- |
| Thiocta thioctic acid | -- | -- |
Ndepụta dị n'elu analogues ọgwụ, nke na-egosi Ndị nọchiri Thiogamma, bụ nke kachasị mma n'ihi na ha nwere otu ihe mejupụtara nke ihe ndị na-arụ ọrụ ma na-emekọ ihe dabere na ngosipụta maka ojiji
Analogs site na ngosipụta na usoro eji
| Aha | Ọnụahịa na Russia | Ọnụahịa na Ukraine |
|---|---|---|
| Lipin | -- | 230 UAH |
| Nwanyị Mọnị | 20 nkp | 15 UAH |
| Mkpụrụ Alder | 47 nkp | 6 UAH |
| Plasenta wepụpụtara amịlị mmadụ | 1685 rub | 71 UAH |
| Chamomile okooko osisi Chamomile officinalis | 25 nkp | 7 UAH |
| Mkpụrụ Rowan | 44 nkp | -- |
| Rosehip Syrup | 29 nkp | -- |
| Mkpụrụ osisi rosehip wusiri ike sirop | -- | -- |
| Rose Hips Rose Hips | 30 nkp | 9 UAH |
| Beroz Immortelle ájá, Hypericum perforatum, Chamomile | -- | 4 UAH |
| Bioglobin-U Bioglobin-U | -- | -- |
| Nchịkọta vitamin Nke 2 Mountain ash, Rosehip | -- | -- |
| Nitricum Gastricumel Argentum, Acidum arsenicosum, Pulsatilla pratensis, Stryhnos nux-vomiсa, Carbo vegetabilis, Stibium sulfuratum nigrum | 334 nkp | 46 UAH |
| Nchikota nke otutu ihe aru oru | -- | 12 UAH |
| Dalargin Biolik Dalargin | -- | -- |
| Dalargin-Farmsynthesis Dalargin | -- | 133 UAH |
| Depụta nchikota nke ọtụtụ ihe dị ike | -- | 17 UAH |
| Teamụaka tii nwere chamomile Altai officinalis, Blackberry, Peppermint, Plantain lanceolate, ọgwụ chamomile, ndị gbara akwụkwọ ịgba ọtọ, na-ahụkarịkarị, fennel nkịtị, Hops. | -- | -- |
| Nnukwu oriri na-eme Hypericum perforatum, Calendula officinalis, Peppermint, chamomile ọgwụ, Yarrow | 35 nkp | 6 UAH |
| Kalgan cinquefoil chịm | -- | 9 UAH |
| Laminaria slani (oke osimiri) Laminaria | -- | -- |
| Lecithin Lipin-Biolik | -- | 248 UAH |
| Moriamin Forte bụ ngwakọta nke ọtụtụ ihe eji arụ ọrụ | -- | 208 UAH |
| Buckthorn suppositories nke bu buckthorn | -- | 13 UAH |
| Ctbelata ngwakọta nke ọtụtụ bekee na-arụ ọrụ | -- | -- |
| Aronia chokeberry Aronia chokeberry | 68 rub | 16 UAH |
| Ọgwụ na ahụike na nchịkọta prophylactic Nke 1 Valerian officinalis, Stinging nettle, Peppermint, owgha mkpụrụ ọka, nnukwu plantain, Chamomile, Chicory, Rosehip | -- | -- |
| Ọgwụ na ahụike na nchịkọta prophylactic Nke 4 Hawthorn, Calendula officinalis, Flax nkịtị, Peppermint, Plantain buru ibu, Chamomile, Yarrow, Hops | -- | -- |
| Phytogastrol a na-ahụkarị, paịlị, chamomile ọgwụ, ịgba ọtọ licorice, ihe na-egbu egbu | 36 nkp | 20 UAH |
| Celandine ahịhịa Celandine nkịtị | 26 nkp | 5 UAH |
| Enkad biolik enkad | -- | -- |
| Gastroflox | -- | -- |
| Eweputa aloe | -- | 20 UAH |
| Orfadine Nitizinone | -- | 42907 UAH |
| Miglustat ikpehe | 155,000 rub | 80 100 UAH |
| Kuvan Sapropertin | 34 300 nkp | 35741 UAH |
| Actovegin | 26 nkp | 5 UAH |
| Apilak | 85 rub | 26 UAH |
| Hematogen albumin nwa nri | 6 rub | 5 UAH |
| Elekasol Calendula officinalis, Chamomile officinalis, Nikikere ịgba akwụkwọ, mmeri Tripartite, sage Medicinal, Rod Eucalyptus | 56 nkp | 9 UAH |
| Momordica compositum ikike homeopathic nke ihe dị iche iche | -- | 182 UAH |
| Iko achicha nke Brewer | 70 nkp | -- |
| Plazmol wepụpụtara nke ọbara enyere | -- | 9 UAH |
| Vitreous Vitreous | 1700 rub | 12 UAH |
| Ubiquinone compositum ikike nke homeopathic nke ihe dị iche iche | 473 rub | 77 UAH |
| Galium Heel | -- | 28 UAH |
| Mkpụrụ ọgwụ thyroididea Compositum nwere nsogbu nke ihe dị iche iche | 3600 rub | 109 UAH |
| Uridine uridine triacetate | -- | -- |
| Vistogard Uridine Triacetate | -- | -- |
Ngwakọta dị iche iche, nwere ike yikọ ọnụ na njiri na usoro nke ngwa
| Aha | Ọnụahịa na Russia | Ọnụahịa na Ukraine |
|---|---|---|
| Immunofit Air nkịtị, Elecampane toro ogologo, Leuzea safflower, Dandelion, licorice ndị gba ọtọ, Rosehip, Echinacea purpurea | -- | 15 UAH |
| Ectis Actinidia, Artichoke, Ascorbic Acid, Bromelain, Ginger, Inulin, Kranberị | -- | 103 UAH |
| Octamine Plus valine, isoleucine, leucine, lysine hydrochloride, methionine, threonine, tryptophan, phenylalanine, calcium pantothenate | -- | -- |
| Agvantar | -- | 74 UAH |
| Elkar Levocarnitine | 26 nkp | 335 UAH |
| Carnitine levocarnitine | 426 rub | 635 UAH |
| Carnivitis Levocarnitine | -- | 156 UAH |
| Lecarnitol Lecarnitol | -- | 68 UAH |
| Igwe na-ere Sto le learnarnitine | -- | 178 UAH |
| Almba | -- | 220 UAH |
| Metacartin levocarnitine | -- | 217 UAH |
| Aha ya bụ Carniel | -- | -- |
| Cartan | -- | -- |
| Levocarnyl Levocarnitine | 241 nkp | 570 UAH |
| Ademethionine Ademethionine | -- | -- |
| Heptor Ademethionine | 277 nkp | 292 UAH |
| Heptral Ademethionine | 186 rub | 211 UAH |
| Adelion ademethionine | -- | 712 UAH |
| Hep Art Ademethionine | -- | 546 UAH |
| Hepamethione Ademethionine | -- | 287 UAH |
| Stimol citrulline malate | 26 nkp | 10 UAH |
| Cerezyme imiglucerase | 67 000 rub | 56242 UAH |
| Emegharịrị agalsidase alfa | 168 rub | 86335 UAH |
| Fabrazim agalsidase beta | 158 000 rub | 28053 UAH |
| Aldurazim laronidase | 62 ikp | 289798 UAH |
| Myozyme alglucosidase alfa | -- | -- |
| Mayozyme alglucosidase alfa | 49 600 nkp | -- |
| Anya nye Halsulfase | 75 200 rub | 64 646 UAH |
| Elaprase idursulfase | 131 000 rub | 115235 UAH |
| Vpriv velaglucerase alfa | 142 000 nkp | 81 770 UAH |
| Eleliso Taliglucerase Alfa | -- | -- |
Etu esi achọta analog dị ọnụ ala nke ọgwụ na-akwụ ụgwọ?
Iji chọta analog na-enweghị ego ọfụma n’egwuregwu, mkpụrụ ọgụgụ ma ọ bụ ntụgharị, nke mbụ anyị na-atụ aro ị attentiona ntị na ihe mejupụtara ahụ, ya bụ otu ihe ahụ na njiri mara maka ojiji. Otu ihe eji eme ọgwụ eme ihe ga-egosi na ọgwụ ahụ kwekọrọ na ọgwụ ahụ, ọgwụ kwekọrọ ma ọ bụ ọgwụ ọzọ. Agbanyeghị, echefula maka ihe ndị na - adịghị ike nke ọgwụ ndị yiri ya, nke nwere ike imetụta nchekwa na ịdị irè. Echefula banyere ndụmọdụ nke ndị dọkịta, ọgwụ ịchọrọ onwe gị nwere ike imerụ ahụ ike gị, yabụ gbaa dọkịta gị mgbe niile tupu ị beforeụ ọgwụ ọ bụla.
Ntụziaka Tiogamma
INWETA Omume ọgwụ Ihe ngosi maka ojiji Ofzọ nke ngwa Iwu iwu nchịkwa nke Thiogamma-Turbo (Thiogamma) Tiogamma Nsonaazụ Ihe ngbanwe Ime Mkparịta ụka ọgwụ ọjọọ Dodoụbiga ya ókè Mpempe mwepụta Mbadamba Tiogamma Ngwọta Thiogamma maka infusion Ọnọdụ nchekwa Ngwakọta Ndị na-ahụ maka ọgwụ Nhọrọ Lipoic acid (mbadamba) Rating: 42 Ihe analogue dị ọnụ ala site na 872 rubles. Lipoic acid bụ Tiogamma nke dị ọnụ ala na-anọchi anya ngwa ahịa ọgwụ ya. Enwerekwa ya n'ụdị mbadamba ụrọ nke nwere usoro dị iche iche nke DV. Mbadamba ụrọ nwere ọgwụ ọnụọgụ ruru 25 mg ka akwadoro maka imeju abụba, imeju imeju, ịba ọcha n'anya na nsí. Ihe analogue dị ọnụ ala site na 586 rubles. Oktolipen - ọgwụ Russia ọzọ, nke bara uru karịa "ihe mbụ". N'ebe a ka ejiri DV (thioctic acid) mee ihe na usoro nke 300 mg kwa Capsule. Ihe ngosi maka ojiji: mamịrị na polyneuropathy na-arịa ọrịa shuga. Tialepta (mbadamba) Rating: 29 Top Ihe analogue dị ọnụ ala site na 548 rubles. Tiolepta bụ ọgwụ maka ọgwụgwọ nke ọrịa eriri afọ, dabere na nsonaazụ nke thioctic acid n'otu usoro onunu ogwu ndị ọzọ ewepụtara na ibe a. O nwere otu uzo ihe ngosi banyere oge a. Nsonaazụ ndị enwere ike. Mgbe a na -ekwu ya n'ọnụ, ọ na-agbadata ngwa ngwa na ngwangwa ngwangwa, iri nri n'otu oge na nri na-ebelata ịmịcha. Bioavailability bụ 30-60% n'ihi nsonaazụ nke mbu site na umeji. Tmax banyere 30 min, Cmax - 4 μg / ml. Site na ntinye / mbido nke Tmax - nkeji 10-11, Cmax gbara ihe dịka 20 μg / ml. Ọ nwere nsonaazụ nke izizi na-agafe imeju. Ọ bụ metabolized na imeju site n'akụkụ yinye na ihikota. Mkpokọta plasma zuru ezu bụ 10-15 ml / min. Mkpụrụ ọka Thioctic acid na metabolites ya site na akụrụ ya (80-90%), na obere ego - anaghị agbanwe agbanwe. T1 / 2 - 25 min. Na-echebara echiche maka ngbanye infusion na usoro maka infusion Thiogamma N'ime / n'ime, n'ụdị infusions, nke ejiri nwayọọ nwayọọ (ihe karịrị 30 nkeji) na-achịkwa na 600 mg / ụbọchị. Usoro akwadoro iji ya bụ izu 2-4. Mgbe ahụ, ị nwere ike ịga n'ihu na -e formomi ọnụ ọgwụ ọgwụ Tiogamma na dose 600 mg / ụbọchị. A na-ewepụ vial ahụ na ngwakọta infusion n'igbe ahụ wee kpuchie ya na ikpe nchedo ọkụ gụnyere, dị ka thioctic acid dị nro maka ìhè. A na-eme infusion ahụ site na vial ahụ. Ọnụego nchịkwa dị ihe dị ka 1.7 ml / min. A kwadebere ihe nzoputa maka infusion site na mkpakọ: ihe dị n'ime 1 ampoule (nwere 600 mg nke thioctic acid) bụ ngwakọta 50-250 nke 0.9% sodium chloride solution. Ozugbo emechara nkwadebe, ihe ikpuchi na-ekpuchi kpuchie karama ahụ na nsonaazụ infusion na-akpata. Ekwesịrị ịnye ngwakọta infusion ozugbo ịkwadebe. Oge nchekwa kachasị nke edozi edozi maka infusion abụghị ihe karịrị 6 awa Mbadamba ụrọ Thiogamma N'ime, otu ugboro n'ụbọchị, na afọ na-enweghị ihe ọwingụ ,ụ, na-enweghị obere obere mmiri. Ogologo oge ọgwụgwọ bụ ụbọchị 30-60, dabere ogo ọrịa ahụ. Enwere ike ikwugharị usoro ọgwụgwọ 2-3 ugboro n'afọ. A na-egosi ugboro ugboro nke oghom n’agha dịka nhazi nke WHO: n’oge (karịa 1/10), ọtụtụ mgbe (erughi 1/10, mana ihe karịrị 1/100), n’adịghị (erughi 1/100, mana karịa 1/1000) adịkarịghị (ihe na-erughị 1/1000, mana ihe karịrị 1/10000), ọ dịkarịghị ike (erughị 1/10000, gụnyere ndị dịpụrụ adịpụ). N'akụkụ nke sisitemu hematopoietic na sistem lymphatic: ọbara ọgbụgba n'ọbara na akpụkpọ ahụ, akpụkpọ ahụ, thrombocytopenia, thrombophlebitis - adịkarịghị ala (maka r-d / inf.), Thrombopathy - adịkarịghị ike (maka ikpehe maka r-d / inf.) mbufụt ọbara ọgbụgba (purpura) - adịkarịghị ala (maka ikpehe maka r-ra d / inf. na r-ra d / inf.). N'akụkụ nke sistem ahụ ji alụso ọrịa ọgụ: usoro mmeghachi omume nfụkasị anụ ahụ (ruo na mmepe nke ụfụ anaphylactic) dị ụkọ (maka tebụl), n'ọnọdụ ụfọdụ (maka njedebe. Maka r-d / inf. Na r-d / inf.). Site n'akụkụ akụkụ akwara dị iche iche: mgbanwe ma ọ bụ mmebi nke ịnụ ụtọ uto bụ ihe a na-adịghị ahụkebe (maka ụdị niile), njakịrị ọdịdọ dị obere (maka ikpechi. Site n'akụkụ akụkụ ahụ nke ọhụụ: diplopia dị ụkọ (maka conc. Maka r-d / inf. Na r-d / inf.). N'akụkụ anụ ahụ na anụ ahụ dị n'okpuru ala: mmeghachi ahụ anụ ahụ na-adịghị mma (urticaria, itching, eczema, faks) - na-adịkarịkarị (maka tebụl), n'ọnọdụ ụfọdụ (maka njedebe. Maka r-ra d / inf. Na r-ra d / inf. .). Site na eriri afọ: ọgbụgbọ, ọgbụgbọ, mgbu nke afọ, afọ ọsịsa - ọ na - adịkarịghị (maka tebụl). Mmeghachi omume ndị ọzọ na-adịghị mma: mmeghachi omume nfụkasị ahụ na ntinye (iwe, redness ma ọ bụ ọzịza) - adịkarịghị ala (maka ikpehe. Maka r-ra d / inf.), N'ọnọdụ ụfọdụ (maka r-ra d / inf.), N'ọnọdụ ngwa ngwa nchịkwa nke ọgwụ ahụ nwere ike ịbawanye ICP (enwere mmetụta nke ịdị arọ na isi), iku ume siri ike (mmeghachi omume ndị a na-apụ na nke ha) - ọtụtụ mgbe (maka ikpehe maka r-d / inf.), dịkarịsịrị ala (maka r-d / inf.), n'ihe metụtara mmelite nke glucose, mbelata nke mkpokọta glucose na ọbara ga-ekwe omume, mgbaàmà nke hypoglycemia nwere ike ime (holo ure, ubara mmụba, isi ọwụwa, ọgba aghara a na-ahụ anya) - ọ dịkarịghị ike (maka ikpehe maka r-d / inf. na tebụl), n'ọnọdụ ụfọdụ (maka r-d / inf.). Ọ bụrụ na otu n'ime mmetụta ndị ọzọ ọ na-akawanye njọ ma ọ bụ mmetụta ọ bụla ọzọ edepụtara na ntuziaka ahụ, ị ga-agwa dọkịta gị. Site na nchịkwa oge nke thioctic acid na cisplatin, a na-achọpụta mbelata nke arụmọrụ nke cisplatin. Thioctic acid na-ejikọ ọla, yabụ, ekwesighi ịkọ ya n'otu oge na nhazi nwere ion metal (dịka ọmụmaatụ, iron, magnesium, calcium). Na-eme ka mmerụ ahụ na-egbochi mbuze nke GCS. Site na oge nke thioctic acid na insulin ma ọ bụ ọgwụ hypoglycemic ọgwụ, enwere ike ịbawanye nsonaazụ ha. Ethanol na metabolites ya na-ebelata ike nke thioctic acid. Ihe mgbakwunye maka itinye uche maka nkwadebe nke ihe ngwọta maka infusion na ngwọta maka infusion Thioctic acid na-emeghachi na ụmụ irighiri shuga, na-akpụ ihe mgbagwoju anya soluble, dịka ọmụmaatụ, na-enwe mmiri nke levulose (fructose). Ngwurugwu ngwongwo infịctic acid na-ekwekọghị na ngwọta nke dextrose, Ringer na ihe ngwọta na-eme na disulfide na SH-otu. Mgbaàmà nke ọgwụ ị .ụbiga mmanya ókè Tiogamma: ọgbụgbọ, ọgbụgbọ, isi ọwụwa. N'ihe banyere ị doụ ọgwụ ike sitere na 10 ruo 40 g nke thioctic acid yana mmanya, a hụrụ ọnọdụ mmanya, ruo na nsonaazụ ya. Mgbaàmà nke oke ịdoụbiga mmanya ókè: mkpaghasị uche uche ma ọ bụ mgbakasị ahụ, nke na-esochikarị mmepe nke ihe ọdịdọ na oke acidosis. Akọwaputakwara bu ikpe nke hypoglycemia, ujo, rhabdomyolysis, hemolysis, mgbasa nke intravascular coagulation, ụmị ụmị ọkpụkpụ na ọdịda nke ọtụtụ akụkụ. Ọgwụ: symptomatic. Enweghị ọgwụ mgbochi akọwapụtara. Thiogamma - tinye uche maka nkwadebe nke ihe ngwọta maka infusion, 30 mg / ml. 20 ml na ampoules nke emere site na iko aja aja (ụdị I). A na-etinye ntụpọ ọcha na ampoule ọ bụla na agba. A na-etinye ampoules ise n'ime kaadiboodu na nkewa. Ejiri plop 1, 2 ma ọ bụ 4 tinye ọnụ na -echebe ìhè ọkụ nke emere site na mkpụrụ ojii ojii, nke etinyebere ya na igbe kaadiboodu. Thiogamma - ngwọta maka infusion, 12 mg / ml. 50 ml na karama emere nke iko aja aja (ụdị nke II), nke ejiri roba ndị mechiri emechi emechi. A na-edobe plọg ahụ site na iji okpu aluminom, na akụkụ nke akụkụ ahụ nwere polypropylene gas. A na-etinye karama 1 ma ọ bụ karama na ikpere na-acha ọkụ (dịka ọnụ ọgụgụ karama) nke ejiri ojii ojii na akụkụ kaadiboodu tinye n'ime igbe kaadi. Thiogamma - mbadamba mkpuchi, 600 mg. 10 mbadamba n'ime blisters nke emere na PVC / PVDC / aluminom foil. 3, 6 ma ọ bụ 10 blisters na-etinye n'ime igbe kaadiodu. 1 ampoule nke uche maka nkwadebe nke ihe ngwọta maka infusion Tiogamma nwere ihe eji arụ ọrụ: meglumine thioctate 1167.7 mg (nke kwekọrọ na 600 mg nke thioctic acid). Ndị ọkachamara: macrogol 300 - 4000 mg, meglumine - 6-18 mg, mmiri maka injection - ruo 20 ml 1 karama nke Tiogamma infusion solution nwere ihe dị n'ọrụ: nnu meglumine nke thioctic acid 1167.7 mg (nke kwekọrọ na 600 mg thioctic acid). Ndị ọkachamara: macrogol 300 - 4000 mg, meglumine, mmiri maka injection - ruo 50 ml. 1 Thiogamma Mbadamba ụrọ nwere ihe nọ n'ọrụ: thioctic acid 600 mg. Ndị pụrụ iche: hypromellose - 25 mg, colloidal silicon dioxide - 25 mg, MCC - 49 mg, lactose monohydrate - 49 mg, sodium carmellose - 16 mg, talc - 36.364 mg, simethicone - 3.636 mg (dimethicone na silicon dioxide colloidal 94: 6 ), magnesium stearate - 16 mg, shei: macrogol 6000 - 0.6 mg, hypromellose - 2.8 mg, talc - 2 mg, sodium lauryl sulfate - 0.025 mg. Ndị ọrịa na-arịa ọrịa shuga chọrọ nlebara anya ịbanye n'ọrịa glucose ọbara oge niile, ọkachasị na usoro ọgwụgwọ mbụ. N'ọnọdụ ụfọdụ, ọ dị mkpa iji belata dose insulin ma ọ bụ ọgwụ hypoglycemic ọgwụ iji zere mmepe nke hypoglycemia. Ọ bụrụ na ihe mgbaàmà hypoglycemia mere (ọgbụgba, ọsụsọ, isi ọwụwa, nsogbu anya, ọgbụgbọ), ekwesịrị ịkwụsị ọgwụ ozugbo. N'ọnọdụ ndị dịpụrụ adịpụ, mgbe ị na-eji ọgwụ Tiogamma na ndị ọrịa na-enweghị nchịkwa glycemic na n'ọnọdụ dị oke ala, mmeghachi omume anaphylactic siri ike nwere ike ịmalite. Ndị ọrịa na-ewere Thiogamma kwesịrị ịhapụ ị alcoholụ mmanya. Mmanya na-aba n'anya n’oge ọgwụgwọ na Tiogamma na-ebelata mmetụta ọgwụgwọ ma ọ bụ ihe dị ize ndụ na-eso akpata mmepe na ọganihu nke neuropathy. Mmetụta ikike nke ịnya ụgbọ ala ma ọ bụ rụọ ọrụ nke chọrọ ịba ụba nke mmeghachi omume anụ ahụ na nke uche. Tnweta Tiogamma emetụtaghị ikike ịnya ụgbọ ala ma jiri usoro ndị ọzọ rụọ ọrụ. Agbakwunye maka mbadamba mkpuchi. Ndị ọrịa nwere mkpụrụ osisi fructose na-eketa ekwo ekwo, na-arịa ọrịa glucose-galactose malabsorption ma ọ bụ ụkọ glucose-isomaltose ekwesịghị iwere Tiogamma. Otu mbadamba mkpuchi nke Tiogamma 600 mg nwere ihe na-erughị 0.0041 XE.
n'iji ọgwụ eme ihe
Tiogamma
Thiogamma-Turbo na-arụ ọrụ bụ acid thioctic (alfa-lipoic) acid. A na-eme acid acid n’ime ahụ ma rụọ ọrụ dịka coenzyme maka ume metabolism nke alpha-keto acid site na decarboxylation oxidative. Thioctic acid na - eduga n'ịbelata glucose na ọbara ọbara, na - enye aka na nchịkọta nke glycogen na hepatocytes. A na-ahụta ọgba aghara metabolism ma ọ bụ enweghị nke thioctic acid na nchịkọta nke ụfọdụ metabolites ahụ (dịka ọmụmaatụ, ahụ ketone), yana ọ bụrụ na egbu egbu. Nke a na - eduga n'ọgba aghara na yinye aerobic glycolysis. Thioctic acid dị na anụ ahụ n'ụdị 2: belata na oxidized. Bothdị abụọ a na-arụ ọrụ physiologically, na-enye antioxidant na mgbochi na-egbu egbu.
Acid Thioctic na-achịkwa metabolism nke carbohydrates na abụba, na-emetụta metabolism nke cholesterol n'ụzọ dị mma, nwere mmetụta hepatoprotective, na-eme ka ọrụ imeju dịkwuo mma. Mmetụta bara uru na usoro mmeghachi azụ na akwara na akwara. Ngwongwo ọgwụ nke thioctic acid yiri nke vitamin B .. N’oge mbu site na imeju, thioctic acid na-eme mgbanwe ndị dị mkpa. Na sistemụ ọgwụ ahụ siri ike, a na-ahụ mgbanwe ndị mmadụ n'otu n'otu.
Mgbe ejiri ya n'ime, ọ na-adị ngwa ngwa ma ọ bụrụhaala kpamkpam na usoro nri. Metabolism na - aga n'ihu site na iji sọks nke akụkụ ụrọ nke thioctic acid na conjugation ya. Mwepu ọkara ndụ Tiogamma (Tiogamma-Turbo) sitere na minit 10 ruo 20. Kpochasịrị mmamịrị, yana metabolites nke thioctic acid.
Na-arịa neuropathy mamịrị iji melite uche anụ ahụ.
Thiogamma-Turbo, Thiogamma maka nchịkwa parenteral
Ezubere Thiogamma-Turbo (Thiogamma) maka ochichi parenteral site na ngbanye akwara ozi. Maka ndị okenye, a na-etinye 600 mg (ọdịnaya nke vial ma ọ bụ 1 ampoule) otu ugboro n'ụbọchị. A na-eme infusion ahụ nwayọ nwayọ, maka minit 20-30. Usoro ọgwụgwọ dị ihe dị ka izu abụọ na anọ. N'ọdịnihu, a na-atụ aro ka ime ihe nke Tiogamma na mbadamba nkume. Nchịkwa Parenteral nke Thiogamma-Turbo ma ọ bụ Thiogamma maka infusion ka edepụtara maka nsogbu uche dị oke njọ nke metụtara polyneuropathy mamịrị.
A na-agbanye ọdịnaya nke karama 1 nke Thiogamma-Turbo ma ọ bụ 1 ampoule nke Thiogamma (600 mg nke ọgwụ) na 50-250 ml nke 0.9% sodium chloride solution. Ọnụego mgbakwunye intravenous - ọ bụghị ihe karịrị 50 mg nke thioctic acid na nkeji 1 - nke a kwekọrọ na 1.7 ml nke ihe ngwọta nke Thiogamma-Turbo (Thiogamma). Ekwesịrị iji nkwadebe dilution ozugbo agwakọta ya na ihe mgbaze. N'oge ọgbụgba, a ga - eji ihe pụrụ iche na - echebe ọkụ si na ọkụ.
Mbadamba mbadamba ihe eji eme ihe. A na-atụ aro ịkọ ọgwụ 600 mg nke ọgwụ 1 oge kwa ụbọchị. A ga-elo mbadamba ihe niile kpamkpam, were ya n'agbanyeghị nri, were mmiri zuru oke sachaa ya. Ogologo oge ọgwụ ọgwụ sitere na 1 ruo ọnwa anọ.
Sistemụ akwara Central: n’ọnọdụ ndị a na-adịghị ahụkebe, ozugbo ị ofụ ọgwụ n’ụdị nke infusion, mkpịsị akwara na-emegharị ahụ.
Akụkụ Sense: imebi mmetụta nke uto, diplopia.
Sistem hematopoietic: purpura (ọrịa mbufụt), thrombophlebitis.
Mmeghachi omume hypersensitivity: usoro mmeghachi omume nwere ike ibute ujo anacticlactic, eczema ma ọ bụ urticaria na ntụtụ.
Usoro nri (maka mbadamba Tiogamma): ngosiputa nke dyspeptik.
Ndị ọzọ: ọ bụrụ na a na-elekọta Thiogamma-Turbo (ma ọ bụ Thiogamma maka nchịkwa parenteral) ngwa ngwa, ịda mbà iku ume na mmetụta nke ntachi isi na mpaghara isi ga - ekwe omume - mmeghachi omume ndị a na-akwụsị mgbe mbelata nke ọnụego. Possible nwekwara ike: hypoglycemia, fla ọkụ, ọgbụgba, ọsụsọ, obi mgbu, mgbada ọbara, ọgbụgbọ, ọhụhụ isi ọwụwa, isi ọwụwa, vomiting, tachycardia.
• Ọnọdụ ndị ọrịa na-eme ka ọ dị mfe ịkpalite mmepe nke lactic acidosis (maka Thiogamma-Turbo ma ọ bụ Thiogamma maka nchịkwa parenteral),
• afọ ụmụ,
• oge ime na lactation,
• mmeghachi omume nfụkasị sitere na acid thioctic - ma ọ bụ ihe ndị ọzọ nke Thiogamma (Thiogamma-Turbo),
• oke ịba ọcha n'anya ma ọ bụ akụrụ.
• nnukwu ọkwa nke infarction myocardial,
• ụzọ ndụ nke iku ume ma ọ bụ akwara obi dara ada,
• akpịrị ịkpọ nkụ,
• a chronicụrụma,
• nnukwu ihe mberede ụbụrụ.
N’ime afọ ime ma ọ bụ na-a breastụ ara, anaghị atụ aro ojiji nke Thiogamma na Thiogamma-Turbo, ebe ọ bụ na enwebeghị ahụmịkị ọgwụ na ọgwụ banyere ide ọgwụ.
A na-abawanye ịdị irè nke ọgwụ hypoglycemic na insulin na njikọta nke Thiogamma (Thiogamma-Turbo). Ngwurugwu Thiogamma-Turbo ma ọ bụ Thiogamma ekwekọghị na ihe mgbaze nwere ụmụ glucose, ebe ọ bụ na thioctic acid na - akpụkọta ogige mgbagwoju anya nwere glucose. Na nyocha nke vitro, thioctic acid meghachiri ya na ogige ion. Dịka ọmụmaatụ, onyinye nwere cisplantine, magnesium, na iron nwere ike belata utịp nke ikpeazụ mgbe ejiri ya na thioctic acid. A na - ejikarị solvent ndị nwere ihe jikọrọ ngwakọta disulfide ma ọ bụ ìgwè SH iji gbarie usoro Thiogamma-Turbo (Thiogamma) (dịka ọmụmaatụ, ngwọta Ringer).
Annwebiga ókè nke Tiogamma (Tiogamma-Turbo), isi ọwụwa, ọgbụgbọ, na ọgbụgba ga-ekwe omume. Usoro ọgwụgwọ a na-egosi Symptomatic.
Tiogamma Turbo
Ngwọta maka infrenteral infusion na 50 ml vials (1.2% thioctic acid). Na ngwugwu - 1, karama iri. Agụnyere ihe pụrụ iche a na-agaghị egbochi.
Nnukwu mbadamba ọgwụ 600 mg maka ojiji maka ime. Na ngwungwu 30, 60 mbadamba.
Ngwọta maka nchịkwa parenteral na ampoules nke 20 ml (3% thioctic acid). Na ngwugwu - 5 ampoules.
N’ebe a na-echebe ka ọkụ ghara ịdị, mgbe ọ na-enwe ọ̀tụ̀tụ̀ okpomọkụ nke 15 ruo 30 Celsius. Ngwọta a kwadebere maka infusion intravenous n’okpuru nchekwa. Ampoules na vials kwesịrị ịdị na nkwakọ ngwaahịa mbụ.
Tiogamma Turbo
Ihe na-arụ ọrụ (na 50 ml): thioctic acid 600 mg.
Ihe ndi ozo: mmiri maka injection, macrogol 300.
50 ml nke Tiogamma-Turbo infusion solution nwere nnu meglumine nke alpha-lipoic acid n’otu n’ime 1167.7 mg, nke kwekọrọ na 600 mg nke thioctic acid.
Tiogamma
Ihe na-arụ ọrụ (na mbadamba 1): thioctic acid 600 mg.
Ihe ndi ozo: colloidal silicon dioxide, celclose microcrystalline, talc, lactose, methylhydroxypropyl cellulose.
Tiogamma
Ihe na-arụ ọrụ (na 20 ml): thioctic acid 600 mg.
Ihe ndi ozo: mmiri maka injection, macrogol 300.
20 ml nke Tiogamma infusion solution nwere nnu meglumine nke alfa-lipoic acid n’otu n’ime 1167.7 mg, nke kwekọrọ na 600 mg nke thioctic acid.
Hormones, ọgwụ analorọ ha na ọgwụ ọgwụ antihormonal
Ọgwụ ndị a na-ahụ maka ọgwụ homonụ nke ọgwụ pcreatic na ọgwụ hypoglycemic synthetic
Mkpụrụ nnọkọ hypoglycemic na-eme ihe
Ihe eji arụ ọrụ: Thioctic acid
Na kalama nwere Thiogamma-turbo nke gbazere, a na-etinye okwu nchebe pụrụ iche, nke a na-etinye na ọgwụ. A na - eji ihe ndị na - enwu enwu kpuchie Thiogamma. Na ọgwụgwọ ndị ọrịa, ekwesịrị ịlele glucose ọbara n'ọbara kwa oge, dabere na nke a ga-agbanwe iji dolata insulin na ọgwụ hypoglycemic iji zere hypoglycemia. Site na iji mmanya (ethanol), a na-ebelata ọgwụgwọ ọgwụgwọ nke thioctic acid. Enweghị ịdọ aka ná ntị ndị ọzọ dị mkpa.Ihe ndi ozo di na Thiogamma
Mlọ ọgwụ
Ofzọ nke ngwa
Nsonaazụ
Mmekọrịta na ọgwụ ndị ọzọ
Dodoụbiga ya ókè
Mpempe mwepụta
Nhọrọ
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Normkpụrụ shuga dị n’ọbara n’ime ụmụ nwoke na ihe ndị na-akpata ihe ndị dị iche
Normkpụrụ shuga dị n’ọbara n’ime ụmụ nwoke na ihe ndị na-akpata ọghọm Ọkwa glucose dị n’ọbara na-agbanwe n’okpuru ihe ndị metụtara physiological na pathologies. Ndị a gụnyere afọ, ụdị ndụ, ịkọ ọdịnihu, ọrịa na-adịghị ala ala. ... -
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