Ọrịa pcreatic

Ọrịa cancer akpa ume - malignant neoplasm nke na - esite na epithelium nke anụ ahụ glandular ma ọ bụ akwara puru iche.

Ọrịa cancer akpa ume
ICD-10	C 25 25.
ICD-10-KM	C25.0, C25.1 na C25.2
ICD-9	157 157
ICD-9-KM	157.1, 157.8, 157.0 na 157.2
Omim	260350
Ọrịa	9510
Medlineplus	000236
eMedicine	med / 1712
Ntughari	D010190

Ọnọdụ nke kansa na-abawanye kwa afọ. Ọrịa a bụ ọrịa cancer kachasị isii n'etiti ndị okenye. Ọ na-emetụta ọkachasị ndị agadi, ọ na - abụkarị ụmụ nwoke na ụmụ nwanyị. Na United States, ọrịa cancer a na-egbu egbu nọ ugbu a n'ọnọdụ nke anọ n'etiti ihe ndị na-akpata ọrịa cancer. Dika nyocha nke ndi American Cancer Society mere, n’aho 2015, a ga achoputa oria a n’onodu 48 960, na ndi oria 40 560 ga-anwu. Ihe ọghọm nke kansa na ndị bi na United States n'oge ndụ bụ 1.5%.

Ihe ndị dị ize ndụ maka kansa kansa bụ:

Ọrịa precancerous gụnyere:

Dịkarị, akpụ na-emetụta isi gland (50-60% nke ikpe), ahụ (10%), ọdụ (5-8% nke ikpe). Enwekwara ọnya zuru oke nke pancreas - 20-35% nke ikpe. Ihe na-eto eto bụ oghere dị egwu na-enweghị oke doro anya; na mpaghara ahụ, ọ na-acha ọcha ma ọ bụ edo edo dị ọcha.

Achọpụtala mkpụrụ ndụ ihe na-eme n’oge na-adịbeghị anya na-emetụta ụdị mkpụrụ ndụ akwara dị njọ, nke nwere ike itinye aka na mmepe nke ọrịa kansa. Dabere na ọmụmụ e bipụtara na akwụkwọ akụkọ Nature Communications, mkpụrụ ndụ a na-elekwasị anya bụ P protein protein kinase gene (PKD1). Site na ime ya, ọ ga - ekwe omume igbochi uto tumo. PKD1 - na - achịkwa ma uto tumo na etuto. Ugbu a, ndị ọrụ nyocha nọ n'ọrụ na -emepụta ihe na - egbochi PKD1 ka ewee nwee ike nyocha ya.

Na nyocha emere na Langon Medical Center na Mahadum nke New York, achọpụtara na ọrịa kansa a na-egbu bụ 59% nwere ike itolite na ndị ọrịa nwere microorganism n'ọnụ ha. Porphyromonas gingivalis. Ọzọkwa, ihe ize ndụ nke ọrịa ahụ dị elu okpukpu abụọ ma ọ bụrụ na achọpụtara onye ọrịa Aggregatibacter actinomycetemcomitans. A na-eme nyocha nyocha nke ga-ekpebi ohere nke ịrịa ọrịa cancer akwara.

Na mkpokọta, enwere ụdị usoro ọgwụgwọ ọrịa kansa ise na ise:

• Adenocarcinoma
• Carcinoma squamous
• Cystadenocarcinoma
• Acinar cell carcinoma
• Ọrịa cancer na-enweghị isi

A na-ahụkarị ihe adenocarcinoma na 80% nke ọrịa cancer akpa ume.

Ọrịa lymphogenic metastasis nke ọrịa cancer akpa ume nwere nkebi anọ. Na ọkwa nke mbụ, ọ na - emetụta ọrịa lymph no (n’akụkụ isi pancreas), na nke abụọ - retropiloric na hepatoduodenal, mgbe ahụ celiac na ọkwa mesenteric lymph nodes na ọkwa nke anọ - retroperitoneal (paraaortic) lymph nodes.

Hematogenous metastasis na-eduga na mmepe nke metastases dị anya na imeju, akpa ume, akụrụ, ọkpụkpụ.

Na mgbakwunye, enwere ntụgharị mkpụrụ ndụ tumo na peritoneum.

Ọkpụkpọ TNM nyocha nke metụtara naanị carcinomas exocrine na agwọ ọrịa neuroendocrine, gụnyere carcinoids.

Ọkpụkpụ T - isi

• Tx - ọnwale isi ya enweghị ike nyocha
• T0 - enweghi data na mbu
• Tis - carcinoma na ọnọdụ
• T1 - oria na - erughi ihe karịrị 2 cm n’ime akụkụ buru ibu n’etiti pancreas
• T2 - akpụ buru ibu karịa 2 cm n’ime akụkụ buru ibu n’etiti pancreas
• T3 - akpụ na-eto eto karịa akwara, mana ọ naghị emetụta akpịrị celiac ma ọ bụ akwara dị elu.
• T4 - akpụ na-etolite na ogwe celiac ma ọ bụ akwara dị elu

Tis na-etinyekwa ọgwụ intanepithelial pancreatic III.

N - mpaghara lymph nodes

• Nx - Enwere ike ịtụle nzere mpaghara.
• N0 - enweghị metastases na mpaghara mpaghara lymph
• N1 - enwere metastases na mpaghara mpaghara lymph

Ihe ndị edeturu: Mpaghara lymph nodes bụ mpaghara periopancreatic, nke nwere ike kewaa dịka ndị a:

M - metastases dị anya

• M0 - enweghị nnukwu metastases,
• M1 - enwere metastases ndị dị anya.

A na - akọwapụtakarị oria nke kansa a na - egosi ọria akwara na - ekwupụta na etuto ahụ n’ọtụtụ ọnọdụ n’oge ngwụcha nke usoro a. N'ime ihe mgbaàmà ahụ, jaundice mgbochi na-abụkarị n'oge germin ma ọ bụ mkpakọ nke bile.

Ọ bụrụ na akpụ ahụ na-emetụta isi gland, mgbe ahụ ọ na-egosipụta onwe ya dị ka ọrịa Courvoisier: n'elu palpation nke aka nri elu akụkụ nke afọ ahụ, ọnya afọ na-abawanye n'ihi nrụgide na-enweghị isi. Ọrịa cancer ara na anụ ahụ na-esochi ya na mgbu na-egbu mgbu, nke na -ezu ala azụ ma dabere n'ọnọdụ ahụ. Ọkpụkpụ nke afọ na eriri afọ na-efe efe na-akpata ọgba aghara na ikike ha. N’ọdị n’ihu, ọrụ gland na akụkụ ahụ ndị ọzọ nke ngwụcha nri na-akụghasị. Enwere ike obara site na akụkụ ahụ metụtara.

Ọrịa kansa na-esokwa mgbaàmà ndị a na-ahụkarị na etuto ahụ jọgburu onwe ya: ị cancerụ oké mmanya, agụụ na-ebelata na ibu ahụ, adịghị ike izugbe, ahụ ọkụ, wdg.

Researchzọ nyocha usoro ọdịnala bụ ultrasound na ntụnyere tomography na nkwalite bolus iche. Methodszọ ndị a ga-enyere anyị aka iji anya nke uche anyị hụ ọhụụ nke isi akwara, kamakwa ịchọpụta ọnụnọ nke metastases, pathology concomitant. Na mgbakwunye, a na-eji usoro X-ray dị ka ihe ngosi si dị, dị ka nyocha nke afọ na duodenum na barium sulfate (iji nyochaa ọnụnọ nke ntụpọ ndochi n'ihi mkpakọ), endoscopic retrograde cholangiopancreatography (iji nyochaa njupụta nke bile duct na pancreatic duct les, nyocha nke morphological). Maka ebumnuche nchọpụta, enwere ike iji laparotomi nwere biopsy.

Na mgbakwunye na ụzọ iji chọpụta njirimara anatomical nke e guzobere pancreas, enwere ụzọ ndị nwere ike ikpebi prognosis nke ọrịa n’otu n’otu. Otu n'ime ụzọ ndị a bụ mkpebi siri ike nke matriks metalloproteinases dị n'ọbara.

Dezie Endoscopic Ultrasound

Nnukwu ọganihu na nchoputa nke ọrịa akwara na mbido mbụ bụ endosonography (endoscopic ultrasound). N'adịghị ka ultrasound a na-ejikarị eme ihe, a na-eji endoscope na-agbanwe agbanwe na igwefoto vidiyo na nyocha ultrasound maka endosonography, nke nwere ike itinye ya na eriri afọ ozugbo ka e guzobere ọmụmụ. Endosonography na-edozi nsogbu nke ịkọwapụta ihe osise na-ebilite mgbe a na-enyocha akụkụ ahụ miri emi na usoro transdermal. Na ọrịa cancer ara, endoscopic ultrasound na-enye gị ohere igosipụta nchoputa na 90-95% nke ikpe dokwuo anya na mbido mmalite.

Jack Andraki Tester Dezie

Na mbido afọ 2012, Jack Andraka, nwoke dị afọ iri na ise nke ụlọ akwụkwọ sekọndrị North County na mpaghara Baltimore nke Glen Burnie, Maryland, USA, mepụtara onye na-achọpụta ọrịa kansa nke nwere ike ịchọpụta ọrịa akụrụngwa, akpa ume, na ọrịa cancer. n'oge mmalite site nyochara ọbara ma ọ bụ mmamịrị. Emepụtara tester akọwapụtara na ndabere nke akwụkwọ maka ịme ule ọrịa mamịrị.

Dabere na onye dere, dabere na atụmatụ na-ezighi ezi, usoro a karịrị narị ugboro ngwa ngwa, iri puku kwuru puku ugboro dị ọnụ ala (onye nyocha akwụkwọ maka ọnụ ọgụgụ buru ibu na-adịghị ihe karịrị 3 cents), yana ọtụtụ narị ugboro karịa mmetụta karịa usoro ndị dị tupu. nnwale. Izi ezi nke nkwupụta mbido nwere ike ịbụ 90% ma ọ bụ karịa. Ihe nwude na nyocha nke onye na-eto eto bụ onye nwuru site na ọrịa cancer nke ezigbo enyi nke ezinụlọ nwa nwoke ahụ.

Maka mmepe mmepe ya, Jack Andraca natara onyinye $ 75,000 na Mee 2012 na asọmpi chiemụ akwụkwọ Ọchịchị na Mmụta Sayensị n'ụwa, nke na-eme kwa afọ na USA (Intel ISEF 2012). Nke a bụ Intel nyere aka. N’ọnwa Jenụwarị afọ 2014, e bipụtara otu akụkọ na akwụkwọ akụkọ Forbes nke gbara ajụjụ maka etu esi nwalee Jack Andrak.

• Ntinye aka na ntanetị (dịka ihe gosiri, n'oge enweghị metastases - na 10-15% nke ikpe)
• Redihotherapy (yana njikọ yana ịwa ahụ)
• Chemotherapy
• Usoro homonụ
• Ọrịa Symptomatic (ọrịa izizi, wdg)
• Virotherapy
• Elektrịị Elektrik (Nanorear)

N'ime ụzọ nke ịwa ahụ, mgbanye nke pancreatoduodenal bụ ihe a na-ahụkarị n'ọrịa kansa.Ọrụ Whipple), nke gụnyere iwepu isi pancreas nke nwere akpụ, ngalaba nke duodenum, akụkụ nke afọ na ọnya afọ nke nwere oghere mpaghara. Ihe mgbochi n’ime ịwa ahụ bụ mgbasa nke akpụ ahụ n’ajị nnukwu arịa na ọnụnọ nke metastases ndị dị anya.

A na-enye ndị ọrịa enweghị ọgwụ ekpughere ọnya ọgbụgba, ma a na-enwe irighiri akwara ahụ, ma ọ bụrụ na a gwọghị ya, nwere ike ibute ahụ mgbu na ọnwụ.

Ọnọdụ ọjọọ. Usoro ịwa ahụ ọgbara ọhụrụ nwere ike belata obere oge mmadụ nwụchara. Agbanyeghị, ngbanahụ etiti ahụ mgbe a gbasịrị ya bụ ọnwa iri n’ise dị n’afọ iri na -abu, na ka afọ ise lanarị na-erughị 20%. Y’oburu na iwepu ihe itu n’ucha apughi ime, igbapu nlọghachi na-eso mgbe obula, n’ile ndi oria n’ebido ijegharia ndu ndu ya odi okpukpu ato karia ndi n’enweghi ogwu. Ọnọdụ ọgwụ ugbu a anaghị ekwe ka ọgwụgwọ dị mma nke ọrịa cancer akwara na-elekwasị anya n'ọgwụgwọ Symptomatic. N'ọnọdụ ụfọdụ, a na-enye nsonaazụ bara uru site na ọgwụgwọ interferon. Ogologo afọ ise lanarịchara ọgwụgwọ anụ ahụ bụ 8-45%, nke na-eme ya otu ọrịa kachasị njọ.

Ozi izugbe

Ọrịa pcreatic nwere ike itolite ma na endocrine na akụkụ nke exocrine, mana exocrine neoplasms kachasị. N'ime ha, etuto ọjọọ bụ emeri, na 90% nke ikpe ikpere nke adenocarcinoma nọchiri anya ya. Ọrịa tumadi adịghị ahụkebe, ha na - ebulite site na sel nke na - ewepụta enzymes, yana oghere nke akwara (cystadenoma). Ahịhịa guzobere site na mkpụrụ ndụ Langerhans (akụkụ endocrine nke pancreas) nwere ike bụrụ ọrụ hormonal ma ọ bụ inert. Ọkpụkpụ na-eme ka mmiri na-arụ ọrụ nwere ụlọ ọgwụ na-egbukepụ egbukepụ, ebe ha na -emepụta nnukwu ihe nke ihe ndị dị ndụ na-arụ ọrụ ma na-eme ka "oke ikuku" na ahụ. Nchoputa omumu ihe banyere ogwu akwara oncopathology gosiputara na uto nke aru a n’ime umunwanyi ka achoputara ugboro abuo na mgbe ndi nwoke, ihe ogugu kachasi puta bu na 35-50.

Ọdịdị akpụ akpụ akwara

All neoplasms site na mmalite ha ka e kewara na (ọdịiche dị oke iche) na nke jọgburu onwe ya (anaghị elezi ya anya). Na mgbakwunye, a na-ekewa ọrịa akwara dị ka ntughari, nhazi akụkọ ihe mere eme, nkwarụ ọrụ. Ọ nwere ike ịdị n'isi akwara, isi ya, ọdụ ya, agwaetiti nke Langerhans, ma ọ bụ ebe ọnọdụ akwara ahụ dị.

Dabere na ntọala nke akụkọ ihe mere eme, na 80% nke ikpe, isi ọwụwa bụ nke sitere na mkpụrụ ndụ (site na mkpụrụ ndụ acinar na endocrine, epithelium ductal ma ọ bụ agwakọta), akwara ndị na-abụghị epithelial, ọbara na arịa nwere ike ịbụ isi mmalite, na neoplasms nwekwara ike inwe dysontogenetic na metastatic sitere.

A na - ahụta ụdị ọrịa pankadenia (pensadenomas), ọrịa ụkwara ume ọkụ - adenocarcinoma, scirr, squamous and cancer anaplastic cancer: acinar mkpụrụ ndụ acinar (benign - adenomas, malignant - acinar cell cancer), duct epithelium (benign - cystadenomas, malignant - adenocarcinoma, scirr, squamous and cancer anaplastic cancer).

Ọrịa pcreatic endocrine tumor nwere ike ime site na sel nke agwaetiti nke Langerhans (insulinomas, gastrinomas, vipomas) ma ọ bụ nwee nsogbu (carcinoid). Dabere na ogo sel dị iche, ha nwere ike ịbụ nke ukwuu, ọkara, na obere ala; endocrine etuto nke ọrịa agwakọta na nke edoghị anya, mucocarcinoids, ụdị ọrịa kansa adịghị, ọrịa tumor (hyperplasia na ectopy nke pancreatic endocrine sel, polyendocrine neoplasia syndrome) achọpụtakwala.

Nkewa a na –arụ oria akwara na - eso ọnọdụ ndị a: enweghị ọghọm, ọnọdụ arụghị ọrụ, mgbagha: hypofunction, hyperfunction (hypoglycemia na hyperglycemia, achlorhydria, afọ ọsịsa, Zollinger-Ellison syndrome na gastrinoma, Werner-Morrison syndrome with polyandoc neoplasia, hyperecretion nke serotonin).

Ekpesara ọtụtụ akwara, lymphoid na ọrịa na-abụghị epithelial nke pancreas, cystadenocarcinomas, squamous na cancer acinar - akọwapụtara ikpe ndị dịpụrụ adịpụ nke neoplasms ndị a. A na-emepụtakarị akpụ akpụ na-arụ ọrụ na akwara siri ike, mejupụtara ihe karịrị 0.3% nke neoplasms pancreatic niile, n'ime ha anọ bụ insulinoma nọchiri anya. Ọ bụ nanị ọnụnọ hematogenous metastases (ọ na-abụkarị ọrịa ịba ọcha) ga-ekpebi ụdị ọrịa ọjọọ. Neoplasms dị njọ nke akwara mmiri na-aza maka 90% nke etuto ahụ na 80% nke mpaghara pancreatob.

Ọrịa ọgbụgba

Imirikiti etuto ahụ nwere ike ghara igosipụta onwe ha kemgbe ọtụtụ afọ. Ọ bụrụ na ụlọ ọgwụ neoplasm apụtawo, eziokwu ndị a na-ekwu maka ịkwado ọnya ọrịa: enweghị akụkọ ihe mere eme nke ọrịa akwara na-apụtakarị ọnya, ọ bụrụ na ụlọọkpọ akpọpụtaghị ọrịa ahụ na ihe mgbaàmà nke oke ọria, na uto nke neoplasm.

Adenomas sitere na pancreatic sitere na ya enweghi ihe ngosiputa nke ogwu;Cystadenomas na cystadenocarcinomas nwere ike iru nnukwu ibu na n'ihi nke a, a na-ahụ ha anya wee na-aga site na akuku ihu ime. N'otu oge ahụ, onyonyo a na-ahụ maka ụlọ anaghị anọ ogologo oge ma na-apụta na ọkwa ndị nke na-esote, mgbe akpụ ahụ bidoro ịpịpụta eriri abụọ na-efe efe na eriri afọ, eriri afọ, arịa na akwara ndị dị nso.

Cliniclọ ọgwụ kachasị dị ịtụnanya bụ mbufụt na-akpata hormones: ọkwa insulin na-adịgide adịgide n'oge insulinoma na-eduga hypoglycemia, a na-egosipụta gastrinoma na mmepe nke Zollinger-Ellison syndrome (ọnya afọ, nnukwu ọbara ọgbụgba nke gastric, ọrịa ọjọọ), vipomas na-egosipụta site na Werner-Morrison syndrome (afọ ọsịsa). , achlorhydria), carcinoid - hyperserotoninemia na ọrịa carcinoid (ọkụ na-ekpo ọkụ nke ụdị menopausal, afọ ọsịsa, afọ ime, enweghị ike Nke a Machine obi ziri ezi).

Cliniclọọgwụ nke ajọ etuto ahụ nke akwara azụ na-apụtakarị naanị n’oge ngwụcha nke ọrịa, nwere ngosipụta niile na akara nke mmebi ahụ n’akụkụ agbata obi. Mgbaàmà ndị a na-ahụkarị bụ ihe ọ intoụ tumụ na-egbu egbu: mgbu nke afọ na-eme ka azụ daa, oke ibu, asthenia, anaemia, enweghị agụụ. Germination nke tumo na akụkụ gbara ya gburugburu na anụ ahụ gosipụtara onwe ya na ngosipụta nke mmebi ahụ akụkụ ndị a (ascites na vaskụla mkpakọ, jaundice na exocrine pancreatic insufficiency with mgbochi of the bile duct and the bile duct), ihe mgbaàmà nke mmebi afọ, wdg.

Nchoputa nke ihe otite di elu

Maka nchoputa n’oge na ezi mkpebi nke ụdị ọria prọfesọ, ọrụ nhazi nke dọkịta na-ahụ maka ọrịa afọ, dọkịta na-awa ahụ na endoscopist. Na-enweghị iji usoro ọhụụ nke ọhụhụ anya na ntinye kemịkal nke neoplasms, ọ fọrọ nke nta ka ọ bụrụ ihe na-agaghị ekwe omume ịchọpụta etuto ahụ. Ekwesịrị icheta na ọbụna ngwaọrụ nyocha ọhụụ na ụzọ ọhụụ anaghị enwe ike ịza ajụjụ banyere ọdịdị anụ ahụ, yana ahụike ahụike nke ndị dibia bekee dị nnukwu mkpa na ịchọpụta ọrịa neoplasms.

Mbibi nke pancreas ga-egosi site n'ọmụmụ ihe nyocha dị ka nnwale nke ọbara bioche, kọlọtọ, ọmụmụ banyere nzuzo nke ihe ọicesụ juụ nri na esophagogastroduodenoscopy. Nzọụkwụ ọzọ ga - abụ nhọpụta nke ụzọ nyocha ndị a na - ezighi ezi dịka gastrography na duodenography, magnetic resonance pancreatocholangiography, magnetic resonance imaging nke pancreas, gbakọrọ tomography nke trakili biliary. Mgbe ịchọpụtasịrị etinyere n’akwara ndị dị n’akwara ahụ (nke buru ibu nke neoplasm nwere ike ịdị n’agbata 2 mm ruo 200 mm), ọkwa homons na metabolites (adrenaline, norepinephrine, serotonin, cortisol, gastrin, pepaide vasoactive, insulin, glucagon, pancreatic na C-peptide bụ nke kpebisiri n’ọbara) , somatostatin, wdg) na akara ntụgharị (CA19-9, CA 50, CA 242, CEA).

Iji kọwaa ọdịdị ọnya ahụ, a na-ejikwa usoro ịkpọasị: endoscopic retrograde cholangiopancreatography, celiacography na-ewere ọbara site na akwara na-achọpụta ihe na homonụ na ya, na -akpọ ọgwụ transhepatic cholangiography, praprap biocture prap biopsy, laparoscopy. Nnukwu nchoputa choro iji mata oria akwara na-egosi na nchoputa nke onodu a bu ihe di nkpa, ma otutu ihe achoputara iji choputa ya.

Ekwesịrị ịdị iche na oria akwara na -akpata ọnya na-adịghị ala ala, ọrịa akwara, extraorganic retroperitoneal tumor na tumorery nke eriri afọ, banye na ọnya afọ ma ọ bụ duodenum, nnukwu arịa arịa, echinococcosis na cysticercosis na mmebi nke mpaghara hepatopanreatic.

Ọgwụ ogwu na akwara

Ọgwụgwọ urịrị bụ naanị ịwa ahụ: anya dị ka akwara nke anya, isi nkpuchi ahụ, njikọ nke akwara, isi akpụ akpụ. Mgbe ọrụ ahụ gasịrị, a na-eme nyocha ihe mmata nke akụkọ ihe mere eme iji kọwaa ụdị neoplasm.

Na neoplasms ọjọọ, a na-ahọrọ ntụziaka nke ọgwụgwọ dabere n'ọnọdụ ọnọdụ. Ọ bụrụ na onye ọrịa nwere ọrịa carcinoid dị njọ ma ọ bụ ọrịa kansa na-arụ ọrụ nke homonụ nọ n'isi isi, a na-eme ntụrụndụ na ichekwa afọ ahụ. Na gastrinomas, a na-arụkarị gastrectomy, na-ahọ anya na-ahụ anya, yana ụdị ihe a na-ahụkarị, ma ọ bụ na-eduga ndị na-ahụ maka ọrịa na ndị na-awa ahụ ka na-arụ ụka maka arụmọrụ yana ike nke ngwa a.

Usoro ọgwụgwọ siri ike nke etuto ahụ nwere ike ịgụnye radieshon na polychemotherapy (ya na ọnụọgụ mmiri na-abawanye uru, na-arụ ọrụ nke homonụ, malignancy na metastasis nke neoplasm). Ọgwụ nke palliative nke neoplasms ọjọọ na-ezube iweghachi ihe ọ biụ ofụ na-egbu egbu na ihe ọ pancụ ,ụ, iwepu usoro mkpali na ọnya biliary, ma melite ogo ndụ onye ọrịa. Maka ebumnuche palliative, a na-arụ ọrụ ndị a: mwepu nke mpụga nke bile dị ka Kerr na Halsted, ọgbụgba mmiri na-adịghị ala ala nke bile dupe, cholecystectomy, nyocha nke endoscopic nke tumor siri ike nke extrahepatic bile ducts, endoscopic stenting nke bile duct, wdg.

Kpachara anya na-egbochi ọnya akwara neuroendocrine nke nwere homonụ dị ala, ngosipụta a na-anaghị ahụ anya nke hyperecretion endocrine gụnyere ngwakọta nke sandostatin na omeprazole. N'ime ọgwụgwọ tumor dị ka gastrinoma, a na-eji nchikota nke H2 na-egbochi ndị na-anata ọgwụ, anticholinergics na ndị na-egbochi mgbapụta proton.

Amụma na igbochi akpụ akpụ

Nnyocha nke etuto ahụ na-emetụta akwara bụ nke a na-adịghị emerụ emerụ, nke ejikọtara na usoro asymptomatic ha yana nchọpụta oge. Mkpochapụ akpụ ahụ ga-ekwe omume naanị na onye ọrịa ọ bụla na iri, ọ bụla na-amaliteghachi, na 95% nke ọnwa iri na abụọ mbụ mgbe a wachara ya ahụ, a na-achọpụta metastases ndị dị anya. Usoro ọgwụgwọ ejikọtara anaghị adịwanye ọnụego nlanarị: ihe kariri 5% nke ndị ọrịa nwere ajọ ara nke mpaghara akwara na-adị ndụ afọ ise.

Nkọwapụta maka ọrịa akwara dị mma - n'ime mmadụ itoolu n'ime ndị ọrịa iri ọ ga-ekwe omume ịnweta ọgwụgwọ zuru oke. Na mgbakwunye, neoplasms nke ebe a na-akọwa ihe dị ụkọ. Enweghị protinlaxis ọ bụla akọwapụtara n'ọrịa ịba, ọ bụrụ na ị na-agbaso ụzọ ndụ, ezi nri, yana izu ike zuru ezu na-ebelata ohere ọrịa ọ bụla na-akpụ n'ime ahụ.