Kedu ihe nwere ike dochie Tricor: mbadamba analogues

Ọgwụ ọgwụ Tricor so na otu ọgwụ ọgwụ na-agbatị. fibrate. Ngwakọta ọrụ nke ọgwụ ahụ bụ fenofibrate(ewepụtafibroic acid) e jiri mmetụta na-eme ka PPARα pụta ma rite n'ihi nsụkọta ya Apoprotein CIII na mkpali lipoprotein lipasenkwalite lipolysisna mmụba n'ọnụ ọgụgụ ọbara ndị sitere na plasma atherogenic lipoproteinsnwere ọnụ ọgụgụ buru ibu triglycerides. Ofrụ ọrụ PPARα na-emekwa ka ọ bụrụ ihe na - emewanyewanye AI na AII apoproteins.

Mmetụta dị otú ahụ fenofibratena lipoproteinsna-enyere aka belata irighiri ihe VLDLna LDLnwere apoprotein B, na-abawanye irighiri ihe HDLgụnyere AI na AII apoproteins. Na mgbakwunye, ihe ahụ fenofibratebu n'uche idozi usoro mmeputa na catabolism VLDL, nke a na-eduga n'ịba ụba na mkpochapu LDL ma belata njupụta nke dense na ezi urughuru LDL(mmụba data LDLhụrụ na ndị ọrịa na- atherogenic lipid phenotype a na - ebutekwa ya n'ihe egwu nke ọrịa obi na akụrụngwa).

A na-eduzi Ọnwụnwa Ọgwụ ịbelata ikeNjirimara fenofibrategosipụtara mbelata nke ọdịnaya triglyceridessite na 40-55% na cholesterol dum site na 20-25% gburugburu ọkwa HDLsite na 10-30%. Na ndị ọrịa na- hypercholesterolemialarịị LDLnke belata site na 20-35%, ọgwụgwọ fenofibratebutere mgbada nke nguzo: mkpokọta cholesterol na HDL, apoprotein B na apoprotein AI, HDLna LDLnke bụ ihe nrịbama ihe egwu atherogenicity.

Ideringtụle mmetụta dị mkpa fenofibratemaka ọdịnaya triglyceridesna LDLojiji a dị irè na ndị ọrịa nwere hypercholesterolemian'agbanyeghị ma o soro ya hypertriglyceridemiama ọ bụ na ọ bụghị, gụnyere na nsoje hyperlipoproteinemiadị ka ọmụmaatụ na ụdị 2 ọrịa shuga mellitus (amaara arụmọrụ Traicor na oria shuga) N'oge ọgwụgwọ fenofibratembelata dị ukwuu na ọbụna ịhapụ mkpofu extravascular ga-ekwe omume cholesterol(tuberose na tendon) xanthomas).

N'ime ndị ọrịa nwere oke afọ ojuju lipoproteinma obu fibrinogenndi aru diri fenofibrate, a hụrụ mgbada dị ukwuu na ngosipụta a. Usoro ọgwụgwọ fenofibratebutere mgbada nke protein C-reactive na akara ndị ọzọ na-ebute mmerụ ahụ.

Ndị ọrịa nwere hyperuricemiana dyslipidemianwetara uru ọzọ nke ọgwụgwọ fenofibratenke dikwa uticosuric mmetụtana-eduga na ibelata ọdịnaya uric acid ihe dị ka 25%.

Ọmụmụ anụmanụ na ọmụmụ ihe na - esochi egosiwo mbelata fenofibratenchịkọta ọgụgụ plateletn'ihi ikpughe adenosine diphosphate, epinephrine na arachidonic acid.

Agụnyere tricor 145 mg mbadamba microsuzed fenofibrate n'ụdị nanoparticles.

Na plasma mmadụ, achọpụtaghị fenofibrate mbụ. A na-ahụta ngwaahịa kachasị maka plasma nke ọgwụ metabolism fenofibroic acid.

A na-ahụta Plasma Cmax fenofibrate mgbe awa 2-4 gachara ọkwa nchịkwa nke ọgwụ. Ogologo oge iji fenofibrate anaghị eduga na mgbanwe na mkpokọta plasma ya, nke, n'agbanyeghị ụdị njiri dị iche iche nke ahụ onye ọrịa, na-akwụsi ike.

N'adịghị ka nhazi nke ọma, enwere ike ịme nchịkwa ọnụ nke usoro onunu ogwu nke fenofibrate (nanoparticles) n'oge ọ bụla n'ụbọchị, n'agbanyeghị nri, nke na nke a anaghị emetụta mkpokọta plasma kachasị nke fenofibrate na mmetụta ya n'ozuzu ya.

Mgbe oriri n'ime fenofibrate na-enyocha ngwa ngwa hydrolysis esterasesna mwepụta nke plasma fenofibroic acid (isi metabolite). A na-ahụta njikọ siri ike na plasma ọbara fenofibroic acid ya na albumin(karịa 99%). T1 / 2 nke metabolite nke ọgwụ bụ ihe dị ka awa 20. Fenofibrate adịghị etinye aka na metabolism nke metabolsom ma ghara mejupụta mkpụrụ maka CYP3A4.

C withụ ahụ ọgwụ nwere mmamịrị bụ nke a na-eme n'ụzọ kachasị fenofibroic acidka glucuronide conjugate. Ruo ụbọchị 6, a na-ahụ ihe kpochapụrụ fenofibrate zuru ezu.

Mkpochapụ fenofibroic acid adịghị agbanwe ka afọ onye ọrịa dị. Ọgwụ nke ọgwụ adịghị eme. Ngwa ịba ọcha n'anyaiwepu fenofibrate adighi ike.

Mbadamba Tricor 160 mg, ma e jiri ya tụnyere usoro ọgwụgwọ mbụ nke fenofibrate, enwere nnukwu bioavailability.

Na plasma mmadụ, achọpụtaghị fenofibrate mbụ. A na-ahụta ngwaahịa kachasị maka plasma nke ọgwụ metabolism fenofibroic acid.

A na-ahụ Plama Cmax mgbe ihe dị ka awa 4-5 gachara ị oụ ọgwụ ọjọọ. Ogologo oge iji fenofibrate anaghị eduga na mgbanwe na mkpokọta plasma ya, nke, n'agbanyeghị ụdị njiri dị iche iche nke ahụ onye ọrịa, na-akwụsi ike. Nnabata nke usoro ọgwụgwọ a fenofibrate na-abawanye na nri ị jikọtara ya na nri.

Na plasma, naanị ihe bụ isi ngwaahịa fenofibrate metabolism - fenofibroic acidnke ejikọrọ na ike albuminkarịa 99%. T1 / 2 nke metabolite nke ọgwụ bụ ihe dị ka awa 20.

C withụ ahụ ọgwụ nwere mmamịrị bụ nke a na-eme n'ụzọ kachasị fenofibroic acidka glucuronide conjugate. Ruo ụbọchị 6, a na-ahụ ihe kpochapụrụ fenofibrate zuru ezu.

Mkpochapụ fenofibroic acid adịghị agbanwe ka afọ onye ọrịa dị. Ọgwụ nke ọgwụ adịghị eme. Ngwa ịba ọcha n'anyaiwepu fenofibrate adighi ike.

Ihe ngosi maka ojiji

Egosiputara uzo ihe eji eme ihe iji:

• ọgwụgwọ dịpụrụ adịpụ ma ọ bụ agwakọta hypercholesterolemiana hypertriglyceridemia(dyslipidemia IIa, IIb, III, IV, V ụdị) bụrụ nke enweghi ike usoro ọgwụgwọ nrima ọ bụ usoro ọgwụgwọ ndị ọzọ na-abụghị ọgwụ (gụnyere ịba ụba, ịba ụba ọrụ, wdg), karịsịa ọnụnọ nke ihe ndị ọzọ dị ize ndụ metụtara dyslipidemia(ise anwụrụ, ọbara mgbali ike),
• nke abụọ hyperlipoproteinemiamgbe a na-azoputa hyperlipoproteinemian'agbanyeghị na ndabere nke ọgwụgwọ dị mma nke ọrịa na-akpata nsogbu (dịka ọmụmaatụ, dyslipidemiahụrụ na oria shuga).

Ihe ngbanwe

Ebumnuche ebumnuche ọgwụ Tricor bụ:

• dị arọ ọrịa imeju (gụnyere cirrhosis) ma ọ bụ akụrụ(ya na QC erughi 20ml / min),
• hypersensitivity nye fenofibratema obu ihe ndi ozo
• inye ara
• shuga enweghị ndidi,
• pathologies nke gallbladder,
• akụkọ banyere onye ọrịa fototoxicityma obu ndisemgbe ị na - eri fibrates ma ọ bụ Ketoprofen,
• gara aga mmeghachi omume nfụkasị ahụ na soy Lecithin, ahuekerema ọ bụ mmanụ ya, yana nri ndị metụtara ya (ihe ize ndụ nke hypersensitivity),
• ruo 18 afọ.

Eji tricor jiri oke nlezianya mee ihe mgbe:

• odida ịba ọcha n'anya/gbasara akwaraọrụ
• a .ụrụma,
• hypothyroidism,
• arọ akụkọ banyere ihe nketa pathologies olu,
• nnabata nkwekọrịta akpụ,
• na nká.

Aghoro, ntuziaka maka ojiji (usoro na usoro onunu ogwu)

Mbadamba ọgwụ ọgwụ Tricor bu n'uche maka nchịkwa ọnụ n'ụdị niile yana mmiri (200-250 ml). Ntụziaka maka iji Tricor 145 mg na-enye ohere nchịkwa nke mbadamba ọgwụ ahụ, n'agbanyeghị nri, n'oge ọ bụla dabara adaba maka onye ọrịa. Ekwesịrị iji mbadamba mkpụrụ ọgwụ mgram 160 mee nri.

Usoro usoro ọgwụgwọ a na-eji ọgwụ a na Tricor pụtara otu mkpụrụ nri kwa ụbọchị site n'aka ndị okenye nke otu mbadamba 145 mg ma ọ bụ 160 mg. Formsdị usoro ọgwụgwọ a nke Traicor, yana usoro eji achọ ihe nwere fenofibrate nke 200 mg (dịka ọmụmaatụ, Lipantil 200 M) na-ahụta ka ihe dakọtara, n'ihe metụtara nke, mgbanwe site na ị oneụ otu ọgwụ gaa na nke ọzọ ka a na-eme na-enweghị ndozi usoro usoro ọgwụgwọ.

Ndị ọrịa nwere nsogbu gbasara akụrụngwa chọrọ ọgwụgwọ site na belata ọgwụ ha. Ọrịa anaghị eme mgbanwe ọ bụla maka ndị okenye. Ojiji nke Tricor maka ọgwụgwọ nke ndị ọrịa nwereọrịa imeju agụghị akwụkwọ.

Ọgwụgwọ na Tricor kwesịrị ịrụ ogologo oge, ya na nrikenyere onye ọrịa tupu ịmalite ọgwụgwọ. Dọkịta na-aga ahụ kwesịrị ịtụle ịdị mma nke ọgwụgwọ ahụ kwa oge. Ihe edere maka nyocha a bụ ihe eji eme ya lipids(gụnyere mkpokọta cholesterol, triglyceridesna LDL) Ọ bụrụ na enweghị ọgwụgwọ ọgwụgwọ ka ọnwa ole na ole gasịrị (ọ na-abụkarị ọnwa 3) nke ịre mbadamba Tricor, a ga-enyocha ajụjụ banyere izizi nke iji ya ọzọ na ohere nke usoro ọgwụgwọ ọzọ.

Mmekorita

Iji fenofibrate jiri ya mee ihe oge anticoagulantsna - eduga na mmụba na nsonaazụ ha, n'ihi nke a, na ịba ụba nke ọbara ọgbụgban'ihi njupụta anticoagulantsite na njikọta protein. Na mmalite ọgwụgwọ fenofibratenwere ike ikwu iwetulata usoro onye ọrịa si mee anticoagulantsihe dị ka otu ụzọ n'ụzọ atọ, yana ndị ọzọ lekwasịrị anya maka ọnụọgụ ọgwụ ha zuru oke. Usoro onunu ogwu anticoagulantahọrọ na ọkwa nke INR.

Site na iji nkwonkwo eji fenofibrate na Cyclosporin achọpụtala ọtụtụ ihe egwu egwu arụ ọrụ akụrụ. Nchikota ọgwụ ogwu a choro ileba anya banyere oru akwara ndi mmadu na oge eweputara fenofibrate na nnabata nke mgbanwe ulo ogwu.

Of jikọtara fenofibrate na fibrates ndị ọzọ ma ọ bụ akpụrụ akpụ na-eme ka ohere nke nsí jọgburu onwe ya na akwara ike.

Nchoputa microsomesumeji mmadụ (in vitro) kpughere enweghi nke inhibitory fenofibrate na metabolite ya na - fenofibroic acid na isoenzymes cytochrome P450: CYP2D6, CYP1A2, CYP3A4, CYP2E1B, yana mmetụta inhibitory na-adịghị ike na isoenzymes CYP2C19 na CYP2A6 ma na-emezi ihe na CYP2C9.

Ntụziaka pụrụ iche

Denye Tricor oria shuga 2nddị nke abụọ nephrotic syndrome, hypothyroidism, dysproteinemia, mmetụta ọjọọ nke ọgwụgwọ ọgwụ, igbochiọrịa imeju, a .ụrụma na ọnọdụ ndị ọzọ na-egbu mgbu, ọ ga-ekwe omume naanị mgbe ọgwụgwọ mbido nke kpochapụ ihe ndị nke abụọ hypercholesterolemia.

Dọkịta na-aga ahụ kwesịrị ịtụle ịdị mma nke ọgwụgwọ ahụ kwa oge. Ihe edere maka nyocha a bụ ihe eji eme ya lipids (gụnyere mkpokọta cholesterol, triglyceridesna LDL) Ọ bụrụ na enweghị ọgwụgwọ ọgwụgwọ ka ọnwa ole na ole gasịrị (ọ na-abụkarị ọnwa 3) nke ịre mbadamba Tricor, a ga-enyocha ajụjụ banyere izizi nke iji ya ọzọ na ohere nke usoro ọgwụgwọ ọzọ.

Na ndị ọrịa na- hyperlipidemiana-anagide ọgwụgwọ estrogen ma ọ bụ onye ọbịa ogwu ogwu enerieen̄ onọbegụnyere estrogens, kwesịrị ikpebi ihe kpatara izizi ma ọ bụ nke abụọ hyperlipidemiaebe ọ bụ na mmụba na ọkwa lipidsikekwe n’ihi nnabata estrogen.

Megide ndabere nke iji Traicor na ndị ọzọ na-ahụ maka ọgwụgwọ na-ebelata ọkwa nke lipids, mgbe ụfọdụ hụrụ mmụba nke ọdịnaya hepatic transaminases. Ọtụtụ mgbe, mmụba dị otú ahụ agaghị adịte aka, enweghị ihe ọ bụla ma bụrụ nke asymptomatic. N'ime ọnwa iri na abụọ mbụ nke ọgwụgwọ, a na-atụ aro Triicor iji nyochaa ndọtị transaminase(AST, ALT) ọnwa atọ ọ bụla. Ọ bụrụ na onye ọrịa nwere ọkwa dị elu transaminaseọ dị mkpa iji nlezianya nyochaa ọnọdụ ya na, na mmụba nke ọdịnaya nke AST na ALT site na ihe atọ dị na ha atụnyere VGN, kwụsịrị ịnakwere Traicor.

N'oge ọgwụgwọ, Tricor kọwara akụkụ nke mmepe. ọria aru. Ihe puru omume na-ebute oria a n’onodu a bu irighiri oru nye nsogbu n’ebe ndi oria no hypertriglyceridemia, mmetụta nke usọbọ ahụ n'onwe ya, yana ihe ndị ọzọ metụtara ọnụnọ nke gallstones ma ọ bụ nguzobe dị n'ime ya, ya na ihe mgbochi nke agwagbu bile.

Ojiji nke Tricor, yana ogwu ndi ozo na-eweda ọdịnaya lipids, nwere ike ibute nsonaazụ nsị anụ ahụ, ruo na mmepe rhabdomyolysis(na obere okwu). Ugboro nke ụdị ikpe na-abawanye mgbe onye ọrịa nwere akụkọ ihe mere eme nke gbasara akwara na hypoalbuminemia. Nkwụsị nke mmetụta ọgwụ ọjọọ riri ahụ na akwara anụ ahụ bụ ihe ziri ezi n'ihe gbasara mkpesa ndị ọrịa myositisadịghị ike akwara mgbu na nkpisi, agbasa myalgia, yana yana mmụba dị ịrịba ama n'ọrụ phosphokinase creatine(okpukpu ise dị elu karịa VGN). N'okwu ndị a, ekwesịrị ịkwụsị ọgwụ na Tricor.

Nsogbu mpempe akwụkwọ rhabdomyolysismmụba na ndị ọrịa buru amụma na rhabdomyolysisna / ma ọ bụ myopathiesgụnyere ịka nká (ihe karịrị afọ 70), ị alcoholụbiga mmanya ókèn'ihi ibu ọrịa ọrịa akwara, hypothyroidism, arụ ọrụ ezumike. Enwere ike ịgwọ ndị ọrịa nke otu ndị a Tricor naanị ma ọ bụrụ na enwere nnukwu uru nke uru ọgwụgwọ dị ka ihe ga - ekwe omume ịmepụta rhabdomyolysis.

Combined jikọtara fenofibrate na fibrates ndị ọzọ ma ọ bụ statins na-eme ka ohere nke nnukwu njọ belata mmetụta nsí n'ihe gbasara akwara ike, karia nke mbu mọzụlụ. Maka nke a, usoro ọgwụgwọ na Tricor na akpụg'onye ezi omume naanị ma onye ọrịa gwakọta dyslipidemiasiri ike na nnukwu ihe egwu nsogbu obi, na-enweghị akụkọ ya mọzụlụn’okpuru ọnọdụ nlele mgbe niile na-akpata nsị na akwara anụ ahụ.

Bụrụ na nke mmụba larịị creatinineihe karịrị otu ugboro na ọkara karịa VGN, ọgwụgwọ na Trikor kwesịrị ịkwụsị. N'ime ọnwa atọ mbụ ọgwụgwọ, aga-enyocha ihe nlele nke creatinine kwa oge.

Mwepụta wepụtara ya na ihe mejupụtara

Thedị usoro ịtọhapụ Traicor bụ mbadamba ihe eji eme ihe nkiri: nke ukwuu, nke na-acha ọcha, ihe e dere “145” ma ọ bụ “160” n'otu akụkụ (dabere na usoro onunu ogwu), n'akụkụ nke ọzọ - akara ụlọ ọrụ (na blisters nke 10 PC. –5, 9 ma ọ bụ 10 blisters, na blisters nke 14 PC., Na ngwugwu nke 2, 6 ma ọ bụ 7 blisters).

Ngwakọta 1 mbadamba:

• ihe na-arụ ọrụ: fenofibrate - 145 (micronized) ma ọ bụ 160 mg,
• ndị na-ahụ maka ọgwụ (145/160 mg): sucrose - 145/0 mg, sodium lauryl sulfate - 10.2 / 5.6 mg, lactose monohydrate - 132 / 138.4 mg, crospovidone - 75.5 / 96 mg, microcrystalline cellulose - 84.28 / 115 mg, colloidal silicon dioxide - 1.72 / 12.6 mg, hypromellose - 29/0 mg, docusate sodium - 2.9 / 0 mg, magnesium stearate - 0.9 / 0 mg, sodium stearyl fumarate - 0 / 6.4 mg, povidone - 0/160 mg,
• shei (145/160 mg): Opadry OY-B-28920 (titanium dioxide - 8.03 / 8.96 mg, polyvinyl mmanya - 11.43 / 12.75 mg, soya lecithin - 0.5 / 0.56 mg , talc - 5.02 / 5.6 mg, xanthan gum - 0.12 / 0.13 mg) - 25.1 / 28 mg.

Mlọ ọgwụ

Na plasma, achọpụtaghị fenofibrate mbụ. Ihe bụ isi plasma metabolite bụ fenofibroic acid.

A na-enweta ntinye uche nke ihe dị na plasma ọbara mgbe awa 2-4 gachara (145 mg nke ọ bụla) ma ọ bụ 4-5 awa (160 mg nke ọ bụla) mgbe nchịkwa ọnụ nke Tricor gasịrị. Ọgwụ plasma nke ọgwụ ahụ ogologo oge ka ọ kwụsiri ike ma ọ dabereghị n'otu njirimara onye ọrịa ahụ.

Ngwakọta nke Tricor na 145 mg gụnyere fnofibrate micronized n'ụdị nanoparticles. Ọdịiche dị na ụdị ntọhapụ a n'ụdị usoro ọgwụgwọ fenofibrate nke mbụ bụ itinye uche kachasị na plasma na mmetụta n'ozuzu fenofibrate n'ụdị nanoparticles. Ofdị irè nke ọgwụ ahụ esighị na nri a na-eri, yabụ enwere ike iji ya n'agbanyeghị agamiri nri n'oge ọ bụla.

A na-eme ka mmụba nke fenofibrate mgbe ị na-etinye Tricor 160 mg mgbe ị na-eri nri.

Ihe karịrị pasent 99% nke fenofibroic acid bụ ihe siri ike na plasma albumin.

Ndụ ọkara nke fenofibroic acid dị ihe dị ka awa 20.

Fenofibrate mgbe nchịkwa ọnụ na-eme ka mmiri ala ngwa ngwa site na esterases. Naanị metabolite isi ya, fenofibroic acid, dị na plasma.

Fenofibrate abụghị mkpụrụ maka CYP3A4. Achọghị metabolism metabolism.

Cụ mmiri na-apụta site na mmamịrị n'ụdị conjugate nke glucuronide na fenofibroic acid. Fenofibrate na-ekpochapu ihe niile n’ime ụbọchị 6.

Ụ ọgwụ were otu oge ma ogologo oge, ọgwụ anaghị agbakọ.

Site na iji okpokoro akwara adighi egosiputa.

Ntụziaka maka ojiji

Ọkpụkpụ bụ ihe eji egbu egbu. Ndabere nke ọgwụ a bụ fenofibrate, ihe dị n'ime otu agbụrụ nke fibroic acid. E nwere ya n'ụdị mbadamba maka nchịkwa ọnụ.

Ihe mkpuchi nke agba ọcha, oblong, nwere nsogbu na otu na akara nke ulo oru a n'aka nke ozo. Ahịa nke ngwaahịa na usoro dị iche iche: 145 mg ma ọ bụ 160 mg. A na-eji ha na nkwado nke dọkịta mgbe ha gafesịrị nchọpụta ahụ.

Inweta Traicor na-enyere aka belata ọkwa nke triglycerides n'ime ọbara. Edere ọgwụ ahụ iji belata VLDL, LDL, yana iwelie antiatherogenic HDL.

N’agbanyeghi otutu ihe eji eme ihe n ’ogwu, akutabeghi iji usoro fenofibrate amuta ihe.

Ọ bụ mkpebi nke enzyme lipoprotein lipase na-ekpebi ịdị n’ọrụ ọ dabere na ya. Ngwaọrụ nọ n'ọrụ Tricor na-akwalite mmụba n'ọnụ ọgụgụ ndị na-anabata LDL na mkpụrụ ndụ imeju. Nchịkọta cholesterol na-eji nwayọ nwayọ. N'ime ndị ọrịa nwere ọrịa mellitus mgbe nchịkwa gasịrị, a na-achọpụta mbelata ọkwa glucose ọbara.

Edere tricor maka ndị ọrịa nwere ọrịa obi, ndị ọrịa nwere ọrịa ndị a:

• hyperlipoproteinemia nke ụdị IIa, IIb, III na IV,
• hypercholesterolemia,
• hypertriglyceridemia, ma ọ bụrụ na nri dọkịta na-achịkọtara anaghị enyere ya aka ịnọgide na-enwe cholesterol nkịtị ma ọ gaghị ekwe omume ịhazigharị ihe ndị ahụ na-enweghị ọgwụgwọ ọgwụ.

Nwere ike ịzụta ọgwụ ahụ n'ụlọ ahịa ọgwụ na ọnụ ahịa 700 rubles. ruru 900 rub. maka mbukota.

N'ụlọ

Ihe atụ nke Russian ọgwụ Tricor bụ Fenofibrat Canon. Inwere ike ichota ihe ekwenyeghi na ulo ogwu obula na onu ahia. Ọnụ ego ha anaghị agafe 400 rubles., Na ọnụahịa nke Tricor site na 800-850 rubles. na elu.

Fonfibrate Canon dị n'ụdị mbadamba maka nchịkwa ọnụ usoro onunu ogwu nke 145 mg nteputara ihe nkiri. Ọnụ ego nke analogue nke Traicor bụ 500 p.

Nkwakọ ngwaahịa: nkwakọ ngwaahịa - mbadamba 30. Ihe mejupụtara bụ fenofibrate (ya na nke mbụ).

Ngwa maka mmebi iwu ndị a:

• ọrịa nke obi usoro,
• hyperlipoproteinemia nke ụdị IIa, IIb, III, IV,
• hypercholesterolemia,
• hypertriglyceridemia.

Enweghị ọdịiche na ntinye akwụkwọ. Ngosipụta maka iji ya bụ otu ihe ya na ọgwụ Tricor.

Ndị nnọchi ọzọ nke Tricor, nke nwere mmetụta yiri ya na ahụ: Lipantil 200 M, Lofat, yana Nofibal.

Naanị dọkịta na-aga ya kwesịrị ịhọrọ usoro ziri ezi maka ọgwụgwọ.

Lipantil 200 M

Lipantil 200 M dị na Russia na France. Dị ịzụ ahịa: capsules 200 mg. Ọnụ ego ha dị ala karịa ọnụahịa Tricor.

N'ime ụlọ ahịa ọgwụ Lipantil 200 M, a na-ere ya maka 700-750 rubles. kwa ngwungwu, nke ọ bụla n’ime ya nwere ihe mkpuchi 30 nwere kpuchiri ekpuchi, ya na ihe mkpuchi na-acha ọcha.

Ume a na-arụ ọrụ, dị ka ọ dị n'ihe banyere ọgwụ ọgwụ gara aga, bụ fenofibrate. O were ya n’otu ihe eji eme ya, nke edoziri maka otu uzo di elu karia nke Traicor.

Tupu ojiji, jiri nlezianya gụọ ntuziaka ma kọwaa ọnụego kwa ụbọchị nke dọkịta chọrọ. Ọgwụ nwere mgbochi afọ maka ndị ọrịa.

Ihe omumu ozo nke Traicore meputara na France bu Lofat. Ihe na - eme ka ọgwụgwọ ọgwụgwọ ahụ bụ fenofibrate. A na-ere ọgwụ ahụ n'ụdị kapịlị mkpuchi nwere. Usoro onunu ogwu - 250 mg. Onye na-eme ka egbugbere ọnụ na -eme ka ọnụọgụ nke ọrịa dị ka ọgwụ ike gara aga Ọnụahịa ụlọ ahịa nke Lofat bụ ihe dị ka 600 rubles. Ugbu a adịghị na ụlọ ahịa ọgwụ.

Nofibal bụ ihe nnọchianya hypolipPs n'ụdị capsule. Ezubere ya dabere na fenofibrate. Usoro nnabata a na yiri analogues.

• hypercholesterolemia (ụdị IIa),
• endogenous hypertriglyceridemia (ụdị IV),
• hypercholesterolemia.

A na-edebanye ọgwụ ọzọ na ugbu a adịghị na ụlọ ahịa ọgwụ.

Otu dọkịta nyere Nofibal otu dọkịta mgbe ọ chọpụtara ọrịa hypertriglyceridemia endogenous hypertriglyceridemia. Edere ọgwụ ahụ yana nri yana usoro mmega pụrụ iche. Ikwesiri ị drinkụ ọgwụ na 400 ml kwa ụbọchị.

N'agbanyeghị agbanyeghị ọgwụ dị elu, enweghị mmetụta ọ bụla, a na-anabata ya nke ọma. Na mbido, mmetụta ndị egosipụtara na ntuziaka ahụ dọrọ aka na ntị. Nwere ike ikpe ikpe arụmọrụ nke nyocha.

Lipantil 200 M bụ ezigbo ọgwụ. A họpụtara ya maka ọgwụgwọ nke arịa ọbara, belata cholesterol. Oke buru ibu na oke ọbara ọgbụgba kpatara ọnọdụ ahụ gbagwojuru ọnọdụ anya. Nri ndị agụnyere naanị nri dị mma, nke masịrị ha enyereghị aka, dịka ndụmọdụ ndị dọkịta ndị ọzọ si dị.

Ekwesịrị m ịgakwuru ndị na-ere ọgwụ. Dọkịta ahụ rụpụtara nsonaazụ ahụ mgbe ọ gụchara akwụkwọ ahụ. Cholesterol belatara. Na mgbakwunye, ịdị arọ belatara ma ọzịza agala. Capsule ndị ahụ pere mpe, n'ihi ya, ha dabara adaba. Ikwesiri ị drinkụ mmanya otu ugboro n’ụbọchị.

Ọnụahịa dị na ahịa ọgwụ

A na-anata ozi gbasara ọnụ ahịa Tricor na pharmacies dị na Russia na data nke ụlọ ahịa ọgwụ dị n'ịntanetị ma nwee ike ịdịtụ iche na ọnụahịa dị na mpaghara gị.

You nwere ike ịzụta ọgwụ ahụ na ụlọ ahịa ọgwụ na Moscow na ọnụahịa: Tricor 145mg 30 mbadamba 30 - site na 834 ruo 845 rubles.

Ọnọdụ nke inyefe ọgwụ n'ụlọ ọgwụ bụ ọgwụ.

Chekwaa n’ebe kpọrọ nkụ na okpomọkụ ruo 25 Celsius. Ekwela ka ụmụaka ghara iru ya.

Edepụtara ndepụta analogues n'okpuru.

Kedu ihe na - enyere aka Tricor 145 na 160 mg?

Ejiri ọgwụ Tricor na usoro ndị a:

• Hypercholesterolemia na hypertriglyceridemia dịpụrụ adịpụ ma ọ bụ agwakọta (ụdị dyslipidemia iia, ire, III, IV, V) (tab. 145 mg) na (ụdị dyslipidemia iia, ire, III, IV, V) (tab. 160 mg) na ndị ọrịa maka nri ma ọ bụ usoro ọgwụgwọ ọgwụ ndị ọzọ (dịka ọmụmaatụ oke ibu ma ọ bụ mmega ahụ ike) adịghị arụ ọrụ, ọkachasị ma ọ bụrụ na enwere ihe ọghọm metụtara ọrịa dyslipidemia, dị ka ọbara ọgbụgba na ị smokingụ sịga,
• Ọrịa hyperlipoproteinemia nke abụọ na ọnọdụ hyperlipoproteinemia na-adịgide n'agbanyeghị ọgwụgwọ dị irè nke ọrịa na-akpata (dịka ọmụmaatụ, dyslipidemia na ọrịa shuga mellitus).

Mgbe ị na-eji ọgwụ ahụ kwesịrị iso nri.

Mmetụta Ọkpụkpụ nke Tricor

Ntuziaka maka iji ịdọ aka na ntị dọọ aka na ntị nke ọghọm ọgwụ ọjọọ Tricor:

Site na usoro nri: (> 1/100, 1/1000, 1/10 000, 1/1000, 1/10 000, 1/10 000, 1/1000, 1/1000, Contraindications

A machibidoro ya iji Tricor 145 na ọrịa ma ọ bụ ọnọdụ ndị na-esonụ:

• hypersensitivity na fenofibrate ma ọ bụ ọgwụ ndị ọzọ,
• nnukwu ọrịa imeju (gụnyere ọrịa cirrhosis),
• nnukwu nsogbu gbasara akwara (Cl creatinine overdose)

Edebanyeghị ọgwụ ị overụbiga ọgwụ ike ókè, agbanyeghị, iji zere mmeghachi omume na-adịghị mma, a gaghị atụ aro ka ọ gafere ogo akọwara na ntuziaka ahụ.

Ọ bụrụ na mbupute ọghọm nke mbadamba ụkwara buru ibu, a na-atụ aro ka ị bute ọgbụgbọ, ma ọ bụrụ na ọ dị mkpa, kpoo afọ ma nye mbadamba ụrọ.

Ndepụta analogues nke Tricor

Ọ bụrụ na ọ dị mkpa, dochie ọgwụ ahụ, nhọrọ abụọ ga - ekwe omume - nhọrọ nke ọgwụ ọzọ nwere otu ihe eji eme ihe ma ọ bụ ọgwụ nwere mmetụta yiri ya, mana yana ihe ọzọ na - arụ ọrụ.

Analogs nke Tricor 145, ndepụta ọgwụ:

1. Lipantil 200 M,
2. Fonfibrat Canon
3. Ihe mgbapụta.

Ọgwụ ndị yiri ya:

Mgbe ị na-ahọrọ onye nnọchi ọ dị mkpa ịghọta na ọnụahịa, ntuziaka maka ojiji na nyocha nke Tricor 145 anaghị emetụta analogues. Tupu ị dochie ya, ọ dị mkpa ịnweta nkwado nke dọkịta na-abịa ma ọ bụghị iji dochie ọgwụ ahụ n'onwe ya.

Nyocha banyere Tricor 145 mg dị ole na ole na-enweghị atụ. Doctorsfọdụ ndị dọkịta ga-eji ya mee ihe n'ụzọ ziri ezi ka profaịlụ ọrịa nke ndị ọrịa ha, na-ahụ ịdị mma dị elu nke ọgwụ a ma nwee afọ ojuju na nsonaazụ ọgwụgwọ na iji ya. Ndị ọkachamara ndị ọzọ na-elebara ihe Traicor anya na nlezianya ma rịba ama na nsonaazụ ndị ọ bụla nwere ike ị ofụ ọgwụ ahụ (ịmepụta okwute, rhabdomyolysis, fotoensitization) na-emeri nsonaazụ ya.

Ozi puru iche nye ndi n’enye ahuike

Mmekorita

Ojiji nke fenofibrate na ọgwụ anticoagulants na-eduga ná mmụba na nsonaazụ ha, n'ihi ya, na-enwekwu ihe ize ndụ ọbara ọgbụgba n'ihi nchụpụ nke anticoagulant site na njikọ protein. Na mbido ọgwụgwọ fenofibrate, a na-atụ aro ka ọnụọgụ ọgwụ anticoagulants nke onye ọrịa belata belata ihe dịka otu ụzọ n'ụzọ atọ, yana nhọrọ ndị ọzọ ezubere maka usoro ọgwụgwọ ha. A na-ahọrọ usoro ọgwụ anticoagulant dabere na ọkwa nke INR.

Site na iji fenofibrate na cyclosporin jikọtara ọnụ, a chọpụtara ọtụtụ akụkụ siri ike nke mbelata ọrụ ọrụ mkpado. Nchikota ọgwụ ogwu a choro ileba anya banyere oru akwara ndi mmadu na oge eweputara fenofibrate na nnabata nke mgbanwe ulo ogwu.

Of jikọtara fenofibrate na fibrates ndị ọzọ ma ọ bụ akpụrụ akpụ na-eme ka ohere nke nsí jọgburu onwe ya na akwara ike.

Ọmụmụ nke microsomes imeju (in vitro) kpughere enweghị nke inhibitory mmetụta nke fenofibrate na isi metabolite ya, fenofibroic acid, na P450 cytochrome isoenzymes: CYP2D6, CYP1A2, CYP3A4, CYP2E1B, yana adịghị ike inhibitory mmetụta CPPPC2 2

Ntụziaka pụrụ iche

Ekwesịrị ịmalite ọgwụgwọ yana nri cholesterol na nlekọta nke dọkịta.

Ọ bụrụ na enweghị mmetụta na-eju afọ mgbe ọnwa 3-6 nke nchịkwa gasịrị, enwere ike ịkọwa akara nkwekọrịta ma ọ bụ usoro ọgwụgwọ ọzọ.

Ọ na-atụ aro ka nyochaa ọrụ “transperent hepatic” kwa ọnwa atọ n’ime afọ mbụ nke ọgwụgwọ, nkwụsịtụ nwa oge na ọgwụgwọ ma ọ bụrụ na ọrụ ha na-aba ụba, na mwepu ya n’otu oge nke ọgwụ hepatotoxic.

Ọrịa hypolipPs Tricor: ntuziaka maka ojiji, ọnụahịa, nyocha na analogues nke ọgwụ

Mpempe mkpụrụ ndụ ọgwụ Tricor ma 145 na 160 mg nwere ihe dị arụ ọrụ n'ụdị fenofibrate.

Banyere ihe eji eme ọgwụ, ọ na - agbadata ume ala (ma ọ bụ wedata mkpo nke lipids). Ọgwụ a bụ nke otu ọgwụ ọgwụ nke fibrates.

Omume General

N'ụzọ bụ isi, a na-eji ọgwụ ahụ eme ihe maka ọrịa na-ejikọta:

• yana insulin nke gbadoro ụkwụ na nke na-abụghị insulin nke ọrịa shuga mellitus,
• ya na hypercholesterolemia (cholesterol dị n'ọbara), hyperglyceridemia (triglycerides gabigara ókè),
• ya na oria gbara agba (obara di elu nke cholesterol na abụba na triglyceride).
• yana ọrịa hyperlipidemia ndị ọzọ.

Banyere hyperlipidemia, anyị nwere ike ịsị na ha bụ ihe kachasị egwu nye obi na akwara ọbara na isi ihe kpatara ọnwụ, dịka ọmụmaatụ, na obodo dịka United States.

Maka ozi banyere otu nke Tricor n'otu otu ụlọ ọgwụ na ọgwụ ọgwụ, ndị nrụpụta ntuziaka Recipharm Monts, yana Laboratoies Fournier S.A. ọ bụ anọghị ya.

Omume ọgwụ na ihe ngosi

N'oge ọnwụnwa nke ọgwụ Tricor ozugbo n'ụlọ ọgwụ, nnyocha ndị ọrịa mere kpughere na site na enyemaka nke fenofibrate, a na-ebelata ọkwa nke cholesterol na 20 site na 20, ma ọ bụ karịa 25%, yana n'ihe banyere iweda ha triglycerides, ihe ngosi a sitere na 40 na ihe ruru 55%.

Erere Tricor 145 mg

Ọzọkwa, n'ime ndị ọrịa nwere hypercholesterolemia, ngụkọta nke mkpokọta na cholesterol LDL na-ebelata. Ekwesiri iburu n'uche na ogo a bụ otu n'ime mkpebi nke oke ihe ize ndụ nke ọrịa obi obi.

ỌgwụEgosiputara ya dika mgbakwunye uzo nke ọgwụgwọ adighi. Maka ndị dị ka usoro mmega ahụ dị iche iche, ụzọ maka oke ibu, yana iji nri maka ọrịa:

• oké ọbara ọgbụgba,
• hyperlipidemia agwakọtara, ma ọ bụrụ na enwere contraindications maka statins (ọgwụ na-ebelata cholesterol ọbara).
• gwakọtara hyperlipidimia. Mgbe ndị ọrịa nwere nnukwu ihe ọrịa ma ọrịa obi na akwara.
• na edebere mbadamba ọnụnọ ọrịa shuga n'ọnọdụ mgbe nri na mmega ahụ anaghị arụ ọrụ.

Fenofibrate bụ ihe sitere na fibric acid. Ọ na-agbanwe ruru nke lipids n’ime ọbara.

N'oge usoro ọgwụgwọ, a na-ahụ mgbanwe ndị a:

• nwekwuo nwepu ma ọ bụ nhicha ọbara.
• n’ebe ndị ọrịa nọ n’ihe ize ndụ nke ọrịa obi obi, ọ̀tụ̀tụ̀ lipoproteins atherogenic na-ebelata (ruru, nke na-amụba ihe ize ndụ nke atherosclerosis) ma ọ bụ “ọjọọ” kọlestrọl,
• na-enyere aka ịba cholesterol "dị mma",
• ike intravascular nkwụnye ego na-belata nke ukwuu,
• ọkwa fibriogen belatara,
• ọbara na-ebelata ihe ndị dị na uric acid, yana protein C-reactive action na plasma ya.

Oke ọdịnaya fenofibrate na ọbara na-apụta n'ime awa ole na ole mgbe ọ nwesịrị Onye Ọrịa.

Ọbụlagodi n'ihe gbasara iji ọgwụ eme ogologo oge, nke a anaghị eduga n'ọtụtụ ya.

A ga-ewepụ ya kpamkpam n'ime ụbọchị 6-7 kachasị na mmamịrị. N'otu oge ahụ, fenofibrate anaghị abụ nke puru iche n'oge a na-agwọ ọrịa, ebe ọ na-aghọrọ nke ọma na plasma albumin (protein bụ isi).

Ime

Ma ihe omuma banyere nnwale nke ulo ogwu na n’uzo imu ogwu nke ndi nwanyi di ime ezughi.

Dịka ọmụmaatụ, na nnwale na anụmanụ, a chọpụtaghị uto nke tetratogenic (mmepe nke ẹmbrayo nwa n’okpuru mmetụta ọgwụ).

Ọzọkwa, ka a na -eme ọnwụnwa dị iche iche, apụtara apịrị apị n'ihi ọgwụ otu n'ime ụmụ nwanyị dị ime nwere nnukwu ọgwụ ọgwụ. Agbanyeghị, ihe aka dịịrị ndị inyom dị ime egobeghị nke ọma.

Ekwesịrị inye ndị inyom dị ime ọgwụ ọgwụ Tricor ka ọ tụlechara ma ọghọm na ọghọm dị na ya.

Usoro onunu ogwu na ubochi

Ihe dị mkpa ịmara! Ndị mmadụ kuziri ihe ilu ilu ka ime ka oke shuga ha dị ka ọ enjoyụ ...

A na-ewere ọgwụ ahụ n'ọnụ, mgbe ị na-asa mmiri mbadamba nkume. Oge inyoghi inabata na esighi na nri (Tricor 145). Ekwesịrị iji nabata Tricorr 160 n'otu oge iji nri.

Ọgwụ maka ndị ọrịa bụ mbadamba 1 kwa ụbọchị.

Ọzọkwa, ọ bụrụ na ndị ọrịa na mbụ were ọgwụ pulag 160 nke Tricor, ha ga - enwe ike, ma ọ bụrụ na ọ dị mkpa, gbanwee ka ha were ọgwụ milligram 145, na enweghị nhazi. Ndị ọrịa n’oge agadi kwesịrị ị doseụ otu ahịrị - ọ bụghị ihe karịrị 1 mbadamba kwa ụbọchị otu ugboro.

Nyocha amamịghe ahụ n’arụ na akụrụ na akụrụ. Ọbụlagodi na nyocha ndị a na-emegiderịta. Ya mere, Taykor kwesiri iburu ndị ọrịa dị otú ahụ nwere oke nlezianya.

Ọgwụ nwere ogologo oge eji, ebe ịkwesịrị ịgbasochi nri enyere gị na mbụ. Ekwesiri iji nyocha nke arụmọrụ ọgwụ Tricoror naanị site na dibia nọ ya n'oge nyocha nke ọdịnaya nke mkpụrụ egbugbere ọnụ abụọ (abụba na ihe ndị yiri ya), na LDL, cholesterol ngụkọta, yana ọdịnaya nke triglycerides.

N'ihe banyere mgbe ọtụtụ ọnwa ọgwụgwọ adịghị ahụ anya, mgbe ahụ, a ga-atụle nhọrọ ọgwụgwọ ọzọ.

Enwere ndị nọ n'ọnọdụ ọgwụ Tricor

Fenofibrate Canon (mbadamba) Rating: 96 Top

Ihe analogue dị ọnụ ala site na 424 rubles.

Fenofibrat Canon bụ analogue dị ọnụ ala karịa nke na-eritekwa uru nke mmepụta ụlọ. Ọdịdị dị na mbadamba nkume ma nwee otu ụdị ihe eji arụ ọrụ, mana na ọnụahịa dị ọnụ ala karịa Tricor. Dabere na njiri mara maka ojiji na contraindications, enweghị ọdịiche pụtara ìhè dị n'etiti ọgwụ ndị ahụ.

Lipantil 200 M (capsules) Rating: 45 Elu

Ihe analogue dị ọnụ ala site na 69 rubles.

Lipantil 200 M dị iche na Tricor n'ụdị ntọhapụ ma ere ya na capsules, nke a na-etinye na ya. Ihe na-arụ ọrụ bụ otu ihe, mana na obere usoro onunu ogwu ọ bụla. Enwere mgbochi afọ na mgbochi afọ, yabụ tupu ịmalite ọgwụgwọ, anyị na-akwadosi ike ka ị gụọ ntuziaka maka ojiji.

Ọnụ ego na analogues

Ọnụahịa nke Tricor dị na ụlọ ahịa ọgwụ nwere ike ịdị 500 na ruo 850 rubles, dabere na oke (145 ma ọ bụ 160 mg) na oke, yana ndị na-emepụta ya. Ọzọkwa, ọnụahịa ọnụahịa ahụ nwere ike ịdị iche iche site na ọnụahịa ndị ebutere na saịtị ahịa ọgwụ.

Dika analogues nke Tricor, ogwu dika:

Ha dị ọnụ ala karịa Tricor, nwee ndepụta nke contraindications, yana usoro onunu ogwu, nke dọkịta gha aghasiri ikpe ya. N'onwe ha ngwa ha.

Ihe omumu: ndi nyocha

Nyocha banyere ọgwụ Tricor na-adịkarị mma:

• Yuri, Lipetsk, 46 afọ. Banyere shuga, ọ naghị ebelata ya, Tricor na-alụ ọgụ cholesterol nke ọma. Agbanyeghị, achọrọ njikwa site na iji usoro ihe ọkụkụ,
• Elena, Belgorod, 38 afọ. Ọnọdụ izugbe adịla mma. Anọwo m na-aillsụ ọgwụ ruo ihe dị ka otu ọnwa ugbu a, ọ dị ka enwere m oke ibu. N’oge na-adịghị anya, nkwụsi ike nke dọkịta, a ga-anwale m. Ana m atụ anya oge nnabata ọnwa atọ,
• Boris, Moscow, 55 afọ. M na-a theụ ọgwụ Tricor na ọmụmụ nke ọnwa 3. Irè n’okwu m belata triglycerides.

Ihe ịchọrọ ịma gbasara Tricor na vidiyo a:

Ọrịa - ọgwụ iji belata cholesterol ọbara

Tricor bụ otu ọgwụ na-egbusi ike, a na-akpọkwa fibrates.

Aha a bụ n'ihi ihe dị mkpa akụrụngwa - fenofibrate. Ọ bụ ihe dị n'ime fibroic acid.

N'okpuru mmetụta ya, a na-ebelata njikọta nke apoprotein CIII, ma na-emekwa mkpalite nke lipoprotein lipase na-amalite, nke na-akwalite lipolysis ma na-akwalite mwepụta ngwa ngwa nke atherogenic lipoproteins n'ọbara nke nwere triglycerides.

Ihe na-arụ ọrụ nke fibroic acid na ihe ndị mejupụtara ya nwere ike mee ka PPARa rụọ ọrụ ma mee ka njikọ nke AI na apoptoreins rụọ ọrụ ngwa ngwa.

Fenofibrates na-agbazi catabolism na mmepụta VLDL. Nke a na - eduga na mkpochapu nke LDL yana mbelata nke ịba ụba ya na obere irighiri ihe.

You nwere ike gụọ nyocha banyere iji ọgwụ a na njedebe nke edemede na ngalaba pụrụ iche.

Ofzọ nke ngwa

A na-ewere ọnụ dị ka mbadamba ihe niile. A gha were mmiri riri ha niile.

Ọ dị mkpa ị theụ ọgwụ ahụ n'oge ọ bụla, n'agbanyeghị nri maka ọgwụ ahụ na ịta ihe dị n'ọrụ nke 145 mg. Mgbe ị na-eji ọgwụ nwere nnukwu onunu ogwu, ya bụ, 160 mg, ekwesịrị ị were mbadamba oge n’otu oge na nri.

Maka ndị okenye, a na-edenye ọgwụ mbadamba 1 otu ugboro n'ụbọchị. Ndị mmadụ na-ewere Lipantil 200M ma ọ bụ Tricor 160 nwere ike ịmalite iji Tricor 145 n'oge ọ bụla na-enweghị ịgbanwe usoro ahụ. Na-agbanweghi usoro onunu ogwu, onye ọrịa nwere ike gbanwee site na iwere Lipantil 200M gaa Tricor 160.

Ndị okenye otu usoro onunu ogwu ka edeputara ka o si di.

Na akụrụ gbasara akwara ma ọ bụ ọrịa imeju na usoro onunu ogwu na-pre-kpakorita gị dọkịta.

Ihe omumu Nyere iwu ka ị useụ nri ogologo oge, nke edebanyere aha tupu nhọpụta ngwa ọrụ a. Enwere ike inyocha nsonaazụ nke ojiji ya site n'aka dọkịta iji mụọ uche nke lipids n'ọbara ọbara. Ọ bụrụ na mmetụta achọrọ emebeghị n'ime ọnwa ole na ole, mgbe ahụ a gbanwere ọgwụgwọ ahụ.

Achọpụtaghị ịdoụ ọgwụ ọ ,ụdoụ ahụ, mana ọ bụrụ na ihe ịrịba ama ọ bụla apụta, ọgwụgwọ Symptomatic dị mkpa.

Jiri mbadamba nkume mee ihe naanị mgbe ị nyochachara dọkịta gị. Should ekwesịghị ịkọ ọgwụ ahụ n'onwe gị. Enwere ike ịzụta tricor naanị site na ndenye ọgwụ.

Mpempe mwepụta, ihe mejupụtara

A na - enweta tricor n'ụdị mbadamba ihe ọlongụ obụ, ndị a kpuchiri ya na obere ihe nkiri na - acha ọcha na agba. Edebere mbadamba onwe ha na ihe ederede. Nọmba 145 gosipụtara n’otu akụkụ, a na-etinye akara AGBARA n'akụkụ nke abụọ.

Mbadamba 145 mg dị. Ihe ngwugwu nwere ike ịnwe iberibe 10 ruo 300. Enwere ụdị mgbapụta nwekwara usoro onunu ogwu nke 160 mg nke ihe arụ ọrụ. Otu ngwugwu nwere ike ịnwe iberibe 10 ruo 100. N’ime otu kaadiboodu ebe amịpụtara ọgwụ ahụ, enwere blister 3 nke nwere mbadamba na ntuziaka.

N'ime ihe mejupụtara ọgwụ ahụ, ihe kachasị arụ ọrụ bụ microsuzed fenofibrate.

Ihe ndi ozo bu:

• lactose monohydrate,
• sodium lauryl sulfate,
• emecha
• hypromellose,
• sodium scusum
• silica
• crospovidone
• stereta magnesium,
• sulfur lauryl.

Na shei ahụ gụnyere Opadry OY-B-28920.

Vidio: "Atherosclerosis - nsonaazụ nke cholesterol dị elu"

Nsonaazụ

Tricorrh nwere ụfọdụ mmetụta adịghị mma, mgbe ịchọpụtara nke ọ dị mkpa iji kagbuo iji ọgwụ a ma gakwuru dọkịta.

N’oge ime ime

Umu nwanyi di ime na umu nwanyi noo na arua nke oma.

Agbanyeghị, nnwale ndị ụlọ ọgwụ na-akwado ihe ọjọọ na nwa ebu n’afọ emebeghị. Agbanyeghị, ẹmbrayotoxicity gosipụtara na nhọpụta ọgwụ ọnya ọgwụ nye ahụ nwanyị dị ime. Agbanyeghị ọgwụ a abụghị maka ụmụ nwanyị dị ime, n'ọnọdụ ụfọdụ ka enyere ya ụmụ nwanyị oge a mgbe ha na-atụle oke uru na ihe ọghọm dị.

Ọzọkwa, achọpụtaghị mmetụta Tricor nwere n’ebe ụmụaka nọ n’oge a na-a breastụ ara, ya mere ndị dọkịta na-anwa ịghara ịkọ ọgwụ a n’oge a.

Usoro na ọnọdụ nchekwa

Ekwesiri ịchekwa tricor na nkwakọ ngwaahịa onye ọrụ. Ọzọkwa, okpukpo kpụrụ ikike ịchekwa bụ ogo 25.

Ndụ nchekwa nke ọgwụ ahụ na-adabere na ịta nke ihe na-arụ ọrụ n'ime ọgwụ ahụ. Mgbe ị na-azụta mbadamba mbadamba ọgwụ nke 145 mg, ndụ nchekwa ha nwere ike iru afọ atọ. Mgbe ị na-eji mbadamba mbadamba ọgwụ nke 160 mg, ndụ shelf belata otu afọ ma bụrụ afọ abụọ.

Ọnụahịa ọgwụ ahụ dabere na ọ bụghị naanị nha nke ngwugwu (olu nke mbadamba ihe dị n'ime ya) nke emepụtara ya, kamakwa na ntinye uche nke ihe na-arụ ọrụ.

Nkezi ọnụ na Ukraine

You nwere ike ịzụta Tricor na Ukraine na ọnụahịa site na 340 ruo 400 hryvnias kwa otu ọgwụ a na usoro onunu ogwu nke 145 mg (mbadamba 20).

Ọgwụ ndị a so na analogues nke Traicor:

A na-anabata ojiji nke analogues naanị mgbe ị gachara dọkịta ma họrọ usoro dị mkpa.

Na mgbakwunye, ọgwụ a nwere mmekorita. Ọ bụ Lipantil 200M, Ihe mgbapụta, Fonfibrat Canon.

Nchịkọta izugbe banyere ojiji nke Tricor na-agwakọta. Doctorsfọdụ ndị dọkịta, mgbe ha na-ede ọgwụ a, na-ahụ ọnọdụ dị mma na mbelata na ịkọwapụta profaịlụ akụkụ ahụ.

A na-amanye ndị dọkịta na ndị ọrịa ndị ọzọ ịhapụ iji ọgwụ a, ebe ọ bụ na nsonaazụ ya na-ejupụta nsonaazụ ọma nke iji ya.

Agbanyeghị Inwere ike itinye Tricor maka ọgwụgwọ naanị mgbe ị nyochachara dọkịta gị na nyocha akụrụ na umeji. Naanị na nke a, ọ bụrụ na achọpụtaghị ihe ọ bụla na-eduga n'ịbelata ahụike onye ọrịa, ọ ga - ekwe omume ị theseụ ọgwụ ndị a.

Nyocha gbasara ọgwụ ahụ enweghị data ọ bụla na mgbanwe nke ọdịmma mmadụ mgbe ị na-anya ụgbọala.

• Edere ọgwụ tricor maka ọgwụgwọ hyperlipoproteinemia, nke enweghị ike idozi ya na nri nri.
• Jiri ọgwụ naanị ka dọkịta nyere gị aka.
• A na-eji ọgwụ ahụ dum eme ihe n'ime, n'agbanyeghị oge iri nri (belụsọ iji were mbadamba mbadamba ọgwụ nke 160 mg).
• A na - egbochi ọgwụ mgbochi afọ ime n’oge a na - enye nwa ara, ọrịa imeju na akụrụ, na - egbochi ọgwụ ndị mejupụtara ọgwụ ahụ, a naghịkwa akwado ya maka ụmụaka.
• Ogwu ahu nwere otutu nsogbu ndi ozo.
• A na-adụ ọdụ ịkpachara anya iji ọgwụ Tricor na ụfọdụ ọgwụ.

Isiokwu ahụ nyeere gị aka? Ikekwe ọ ga - enyere ndị enyi gị aka! Biko, pịa otu n'ime bọtịnụ:

HypolipPs ọgwụ Tricor - ntuziaka maka ojiji

Otu n'ime ọgwụ inyeaka eji arịa ọrịa shuga bụ Tricor. Ọ naghị emetụta ọgwụ hypoglycemic, mana ọ nwere ike belata ọkwa glucose na ọbara.

Iji ghọta otu esi eji ya n'ụzọ ziri ezi, ịkwesịrị ịchọpụta mpaghara kachasị nke ngwa ya na njirimara bụ isi.

Ozi izugbe, ihe mejupụtara na ụdị ịtọhapụ

Dabere na radar, Tricor bụ ọgwụ na - agbada egbugbere ọnụ - si na cholesterol n'ime ọbara. Ojiji ya na-enyere aka belata oke abụba n’ahụ ma na-egbochi imepụta atherosclerosis.

A na-eme ntọhapụ ya na France, ebe a na-ere ọgwụ a n'ụdị mbadamba. Mmetụta nke ọgwụ ahụ bụ n'ihi akụrụngwa bụ isi, nke bụ fenofibrate.

Can nwere ike iji ya naanị nke dọkịta nyere gị, ebe ọ nwere mmetụta siri ike n'ahụ ahụ. O nwere ike ịdị njọ ma ọ bụrụ na erechaghị ya. Ya mere, enwere ike ịzụta ya naanị site na ndenye ọgwụ.

A na-emepụta ego iji na mbadamba. Ihe kachasị dị mkpa nke ọgwụ ahụ bụ fenofibrate. A gunyere ya na mbadamba ihe dika iri aro 145.

Na mgbakwunye na ya, enwere ihe ndị dịka:

• emecha
• hypromellose,
• sodium docusate,
• stereị magnesium,
• microcrystalline cellulose,
• lactose monohydrate,
• sodium laurisulfate,
• silloon dioxide colloidal.

Ihe ndị a na-enye gị ohere inye ọgwụ ahụ ụdị achọrọ. Mbadamba ụrọ bụ ihe mkpuchi (bp).

Enwekwara mbadamba nkume nke nwere ihe mejuputara ihe ntinye aka nke 160 mg. Ha nwere otu ihe ozo ndi ozo nke ogwu a.

Nchịkọta ọgwụ nwere nhazi dị iche iche. Ha nwere ike tinye site na mbadamba 10 ruo 300 (usoro nke 145 mg) ma ọ bụ site na 10 ruo 100 iberibe (dose nke 160 mg).

Emere ọgwụ ọgwụ na ọgwụ ọgwụ

Iji ghọta ihe achọrọ ọgwụ a, ịkwesiri ịchọpụta atụmatụ nke omume ya.

Fenofibrate nwere mmetụta na triglycerides, belata ego ha. Ọ na - enyere aka belata cholesterol n'ime ọbara. Nke a bụ n'ihi mmebi nke njikọ nke ọdụdụ asịd.

Ojiji nke ọgwụ nwere ike belata ọnụ ọgụgụ fibrinogen. Akụkụ ike na-esighi ike na-arụ ọrụ na glucose, na-enyere aka belata ọkwa ya. Njirimara ndị a na-eme ka Tricor dị irè maka ịgwọ ndị ọrịa atherosclerosis nwere ebumnuche ịmalite shuga.

Fenofibrate ruru ihe kachasị arụ ya mgbe elekere ise gasịchara (nke a na-emetụta njiri ahụ mmadụ niile).

Akụkụ dị ukwuu na ya na-ejikọ ya na albumin, protein protein, na-emepụta acid fenofibroic. A na-eme metabolism ya na imeju. Ihe ahụ nwere mmetụta na-adịgide adịgide - ọ dị ihe dị ka awa iri abụọ iji wepụ ọkara ya. Ọ na-ahapụ ahụ n'ahụ site na eriri afọ ya na akụrụ.

Ihe ngosi na contraindications

Nwere ike ịchọpụta ihe akụrụngwa a na-enyere aka site na ịmụ ntuziaka na ngosipụta maka ebumnuche ya.

A na-atụ aro ka iji ya maka mmebi iwu ndị dị ka:

• hypercholesterolemia,
• hypertriglyceridemia,
• hyperlipoproteinemia.

Site n'ọrịa ndị dị otú ahụ, a na-eji Tricorr mee ihe ma ọ bụrụ na usoro ọgwụgwọ na-abụghị ọgwụ adịghị eweta nsonaazụ.

Ọzọkwa, dọkịta ahụ nwere ike ịkọ ọgwụ a iji merie ọrịa ndị ọzọ dịka akụkụ nke usoro ọgwụgwọ siri ike, ma ọ bụrụ na omume ndị dị otú ahụ kwesịrị ekwesị.

Ekwesịrị icheta na ọnụnọ nke ihe ndị na-egosi na ndenye ọgwụ apụtaghị iji mmanye eji ọgwụ a. Nchọpụta nke contraindications na-amanye gị ịhapụ iji ya.

Ndị a gụnyere:

• nnukwu ọrịa imeju
• nnukwu nsogbu akụrụ
• anabataghị ihe mejupụtara ahụ,
• lactation
• ọrịa ọnya afọ
• afọ ụmụaka.

Enwerekwa ikpe ebe enwere ike iji Tricor mee ihe, mana achọrọ oke ịkpachara anya:

• a .ụrụma
• hypothyroidism
• nká
• imebi imeju na akụrụ.

Nke a pụtara na ị ga - a takeụ ọgwụ a naanị dịka onye ọkachamara si gwara gị. Ngwọta onwe gi nwere ike iduga na nsogbu.

Ndị Ọrịa na Nduzi Pụrụ Iche

Onu ogugu ndi oria a ka akwadoro nlezianya puru iche mgbe eji Tricor bu ndi mmadu ndi a:

1. Womenmụ nwanyị n’oge ime. A na - agbanye ọgwụ ike nke ọgwụ ahụ, ya mere, amachibido iji ya n'oge a.
2. Ndị nne mụrụ nwa. Edebeghi ihe Fenofibrate na aru nke mmiri ara ara ya na nke nwa.N'akụkụ a, ndị dọkịta anaghị eji Trikor maka ndị ọrịa dị otú ahụ.
3. Childrenmụaka. N’agbata afọ 18, a naghị eji ọgwụ a eme ihe, n’ihi na a maghị etu ihe mejupụtara ya nwere ike isi metụta ahụ ụmụaka.
4. Ndị okenye. Maka ụdị ndị ọrịa a, a na-ele iji ọgwụ ahụ anya dị ka ihe na-anabata. Mana tupu nhọpụta ya, ndị ọrịa chọrọ nyocha iji zere nsogbu ndị nwere ike ibute ya. A na-akụkwa usoro onunu ogwu.

Ndị ọzọ (na enweghị ọgwụ mgbochi) nwere ike iji ọgwụ dịka dọkịta nyere ha iwu.

Ekwesịrị ịkpachara anya mgbe ị na-eji Traicor na ọnụnọ nke nsogbu ndị na-esonụ n'ime ahụ:

1. Ọrịa akụrụ. N'ime ọrịa dị njọ nke akụkụ a, a machibidoro iji ọgwụ a iwu. Obere uzọ ihe dị iche iche na-arụ n’ọrụ akụrụ chọrọ nleba anya mgbe niile n’usoro ọgwụgwọ ji ya.
2. Ọrịa imeju. Maka obere nsogbu imeju, dọkịta nwere ike ịkọ ọgwụ Tricor mgbe nyochachara. Nnukwu mmebi bụ ihe kpatara ịhapụ ọgwụ ahụ.

Fenofibrate nwere ike imetụta ọrụ nke imeju, yabụ ọbụlagodi na enweghị nsogbu na mpaghara a, ịkwesịrị ịlele ọnọdụ ya oge ụfọdụ. Ọzọkwa, n'okpuru mmetụta nke ọgwụ ahụ, usoro ịmịnye ọbara ọbara nwere ike ịgbanwe - ọ dịkwa mkpa ịchịkwa nke a.

Njikọ Ọgwụ na Analogs

Ọgwụ nkwanye ugwu gụnyere njikọta ọgwụ ziri ezi ejiri. Ọ bụrụ na otu usoro agbanwe agbanwe mmetụta nke onye ọzọ, nsonaazụ ya nwere ike ịbụ nke a na-atụghị anya ya. Ya mere, ịkwesịrị ịtụle otú Tricor nwere ike isi metụta ọgwụ ndị a na-eji ya na ya.

Ihe ị ga - eme bụ ijikọ ọgwụ a na:

• anticoagulants (fenofibrate na-eme ka mmetụta ha dịkwuo elu, nke na-akpata ihe ize ndụ ọbara ọgbụgba),
• Cyclosporine (akụrụ nwere ike ịrụ ọrụ),
• akwara (enwere ihe ojoo ojoo na aru ojoo).

N’ihe metụtara ọgwụ ndị ọzọ, a naghị achọpụta mgbanwe dị iche iche. Ka o sina dị, onye ọrịa ahụ ga-agwa dọkịta banyere ọgwụ niile ọ na-eji ka ọkachamara ahụ nwee ike ịkọwa ọgwụgwọ zuru oke.

Ihe kpatara iji ngwaọrụ analog nwere ike ịdị iche. Ọtụtụ mgbe, ndị ọrịa na-achọ ọgwụ analogues dị ọnụ ala karịa, ebe ọ bụ na ị drugụ ọgwụ dị oke ọnụ na-aga n'ihu bụ ọrụ dị oke ọnụ.

Ndị ọzọ na-enwe nchegbu banyere mmetụta ndị na-eme ka o siere ha ike ịrụ ọrụ nke ọma. N'akụkụ a, ndị ọkachamara na-ahọrọkarị ọgwụ nwere mmetụta yiri ya.

Ndị a gụnyere:

Offọdụ n'ime ego edepụtara nwere ihe dị ka nke Traicor. Maka ndị ọzọ, mmetụta yiri ya bụ njirimara, n'agbanyeghị ọdịiche dị na ngwa.

Iji jiri mmemme ahụ, ị ​​ga-agakwuru dọkịta gị. Medication -ụ ọgwụ onwe gị dị ize ndụ mgbe niile, yabụ ịkwesịrị ijide n'aka na ọgwụ ahọrọ bụ nke kwesịrị ekwesị maka otu onye ọrịa.

Echiche onye ọrịa

Nyocha banyere ọgwụ Tricor na-adịkarị mma - ọtụtụ na-achọpụta mmetụta bara uru ya n'ahụ yana iwetulata cholesterol ọbara.

Ọnụ ego ọgwụ a na-akwụ na-adabere na usoro nke ihe eji arụ ọrụ dị n'ime ya na ọnụọgụ mbadamba ihe dị na ngwugwu ahụ. Maka ngwugwu nwere mbadamba 30 (145 mg) ịkwesịrị inye site na 750 ruo 900 rubles. Na usoro onunu ogwu nke 160 mg na ngwugwu yiri ya, ọnụahịa maka Tricor ga - abụ 850 ruo 1100 rubles.

Akwukwo ndi ozo ndi ozo choro

Tricorrh: ntuziaka maka ojiji, ọnụahịa, nyocha, analogues »

Tricor bụ ọgwụ nke onye na-emepụta French. Dabere na ntuziaka maka ojiji, eburu ya maka ọgwụgwọ nke ọrịa na akwara.

Ọ bụ nke otu ọgwụ ọgwụ na-ebelata ike, nke a na-akpọkwa fibrates. Aha a na - egosiputa ihe eji eme ihe - fenofibrate.

Ọgwụ a na-ezo aka na ọgwụ sitere na fibroic acid.

Ngwa

N'ime usoro ahụike, Tricor na-eji agwọ ọrịa ndị a:

• hypercholesterolemia na hypertriglyceridemia, ma ndị dịpụrụ adịpụ na agwakọta (ụdị dyslipidemia dị iche iche) n'ime ndị ọrịa nke nri ha ghọrọ adịghị arụ ọrụ, ma ọ bụ usoro ọgwụgwọ ndị ọzọ na-abụghị ọgwụ (usoro nke ebubata oke ibu, ịba ụba mmega ahụ). Nke a dị ezigbo mkpa maka ọnọdụ ebe enwere ihe ọghọm dị ka omume ọjọọ (ị smokingụ sịga) na ọbara mgbali elu.
• hyperlipoproteinemia nke abụọ mgbe akara ya na-adịgide n'agbanyeghị arụmọrụ nke ọgwụgwọ maka ọrịa na-akpata ya (dịka ọmụmaatụ, dyslipidemia na ọrịa shuga mellitus).

Dị Mwepụta

N'ime mmepụta ọgwụ, ọgwụ dị n'ụdị mbadamba abụọ, nke dị iche na ọnụọgụ arụmọrụ (fenofibrate), nke dị na mpịakọta 145 mg (micronized) ma ọ bụ 160 mg

Ndi okacha amara bu sucrose, sodium lauryl sulfate, lactose monohydrate, crospovidone, colloidal silicon dioxide, wdg.

Mbadamba ụrọ ahụ nwere ọdịdị ọfụma, ha na-ekpuchi ihe mkpuchi na-acha ọcha. Edere akara a n'otu akụkụ, ọnụ ọgụgụ ndị dị n'akụkụ nke ọzọ na-egosi ego nke ihe bụ isi na ihe mejupụtara ngwaahịa ahụ (145 ma ọ bụ 160).

A na-etinye mbadamba na blisters nke iberibe iri. Mpempe kaadiboodu nwere ike inwe blister 1 ruo 10.

Ndakọrịta

Ojiji nke Tricor na oge ndi mmadu hypoglycemic nke mejuputara sulfonylureas nwere ike ime ka mmụba a na-emetụta hypoglycemic.

Njikọ nke Tricor na anticoagulants na-apụtaghị ìhè (gụnyere acenocoumarol, warfarin) na-eme ka mmetụta nke ikpeazụ ahụ ka mma.

Enwere echiche banyere ọrụ dị mkpa nke fibrates dịkwuo n'ịhụ mmekọrịta anticoagulants maka ụfọdụ ndị nnabata, yana mmebi nke usoro metabolic ha.

Nchikota ọgwụ a na cyclosporine nwere ike ibute ọrụ gbasara akụrụ na mmụba nke ihe a na ọbara.

Dodoụbiga ya ókè

Egosiputaghi akara akparamaagwa nke oke nfe mgbe a na-achi Traicor site na akwukwo ogwu. Ọzọkwa, enwebeghị ọgwụ mgbochi akọwapụtara. Ọ bụrụ na enwere enyo site na ịdoụbiga ihe ókè, symptomatic ma, ọ bụrụ na ọ dị mkpa, ekwesịrị ịdebe ọgwụ mmezi. Ekpebiela na usoro ịba ọcha n'anya adịghị arụ ọrụ.

Nina P. na nyocha http://otzovik.com/review_2302884.html na-ekwupụta ịdị irè nke ọgwụ ahụ, ọkachasị mkpa ọ dị maka iwetulata cholesterol.

Ka o sina dị, ọ dọrọ aka ná ntị banyere ọgwụgwọ onwe onye, ​​na-emesi ike mkpa nlebara anya ọkachamara mgbe niile na usoro ọgwụgwọ. Onye dere akwụkwọ ahụ gosikwara ike ịnwe mmetụta dị njọ n'oge ọgwụgwọ na Tricor.

Ya mere ya onwe ya nwere otite ahu. Maka nke a, nwanyị ahụ gara ịga ụlọ akwụkwọ nke abụọ wee chọpụta na ọ dị mkpa ịbanye ultrasound nke eriri afọ.

Azụtara ọgwụ ahụ nke ọma dịka ntinye ọgwụ nke dọkịta na-elele nsonaazụ ule oge niile iji jide n'aka na enweghị mmetụta ọ bụla.

Elena K. na ntụle https://health.mail.ru/drug/tricor/ dere na ọgwụ a emetụtaghị ya. Ọ itụrụ ya ọnwa abụọ wee nwee nnukwu ihe mgbu na paresis nke ahụ, yana adịghị ike akwara niile. Ọ mataghị ihe ndozi, maka nke a ọ naghị akwado Tricor maka ojiji.

Alexey P. na nyocha https://health.mail.ru/drug/tricor/ dere na ya ewerela Tricor kemgbe ọnwa anọ. N’oge a, mgbu n’ụkwụ belatara, ahụike bịara ka mma.

Tricor bụ ogwu emere na France. Ejiri ya na ọgwụgwọ ọrịa nke ọrịa obi. Dịka ihe na-eweta mmanụ agbatị, Tricor bụ nke fibrates.

A na-eji ya maka nzube ebumnuche ya na ntuziaka, na nkwanye yana n'okpuru nlekọta nke dọkịta. E nwere ọtụtụ ọgwụ mgbochi na mmetụta ọ na-akpata. Mgbe ị na-a drugụ ọgwụ a, e kwesịrị ilezi anya yana usoro ọgwụgwọ egosipụtara.

Adabara ụmụ nwanyị dị ime na ndị na-actụ nwa, yana ụmụaka.

Chekwaa ma ọ bụ kesaa:

Azụmaahịa: analogues dị ọnụ ala, ntuziaka maka ojiji, ọnụahịa, nyocha

Ihe omumu- A na-eji ọgwụ a eme ihe maka ọrịa shuga na dyslipidemia. Ọ nwere njiri mara hypoliplera.

Usoro nke usoro:

• Ọ na - eme RAPP-alfa n'ọrụ, nke na - eduga n'ịba ụba nke lipolysis,
• Usoro nke apoproteins nke ụdị AI, AII,
• Na -ebelata mkpụkọ nke liheids nke atherogenic na plasma n'ihi ịmịpụrụ elu,
• Na-ebelata cholesterol, triglycerides,
• Na-agbadata cholesterol extravascular cholesterol,
• Na-egbochi nchịkọta platelet metụtara ya na epinephrine, arachidonic acid na ADP.

Banyere ọgwụ dị ọnụ ala iji belata cholesterol - aha, ọnụahịa na nyocha anyị dere ebe a.

Otu ihe dị mkpa dị n’ọgwụ ahụ bụ na n’usoro sistemụ mmadụ, ọkwa fenofibrate rutekarị oke, a na-ahụkarị mmetụta a ka awa 2-3 gachara ọgwụ. Ngwá ọrụ ahụ nwekwara mmetụta uricosuric.

Nnukwu analogues nke Tricor

• Fonfibrat Canon. Ọ dị iche na listi ndị mbụ. A na-eji stachi ọka, colloidal silicon dioxide, ssumum croscarmellose, mannitol, magnesium stearate, povidone K-30, celclose microcrystalline. A na-etinye ya nwayọ nwayọ (mgbe emesịrị ịbanye n'obara ya na ọbara). Ọnụ ego 489 rub.