Egiptiin - nkọwa nke ọgwụ, ntuziaka maka ojiji, nyocha

Hapụ okwu gị

Nchọpụta Ozi Ugbu A, ‰

Asambodo ndenye aha EGIPENTIN

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Mgbe ị na-ehota ihe ọmụma dị na peeji nke www.rlsnet.ru, njikọta isi mmalite ozi a chọrọ.

Ọtụtụ ihe ndị ọzọ na-adọrọ mmasị

Ikike niile echekwabara.

Anaghị anabata iji ihe azụmaahịa.

Ezubere ozi a maka ndị ọrụ ahụike.

Nkọwapụta nke ọgwụ ọgwụ

Ọgwụ antiepileptik. Ihe owuwu kemịkalụ ahụ yiri GABA, nke na-arụ ọrụ dịka onye ogbugbo breeki na sistemụ akwara. A kwenyere na usoro nke gabapentin dị iche na anticonvulsants ndị ọzọ na-arụ ọrụ site na GABA synapses (gụnyere valproate, barbiturates, benzodiazepines, GABA transaminase inhibitors, GABA uptake inhibitors, GABA agonists and GABA prodrugs). Na nyocha nke vitro egosiwo na ọnụnọ nke saịtị peptide ọhụrụ na-ejikọ aka na akwara ụbụrụ, gụnyere hippocampus na cerebral cortex, nke nwere ike metụtara ọrụ anticonvulsant nke gabapentin na usoro ya. Nnukwu ọnụnọ ndị metụtara ọdịnihu anaghị egbochi ọgwụ ọgwụ ndị ọzọ na ndị na-anabata neurotransmitter na ụbụrụ, gụnyere ya na GABAA-, GABAB-, benzodiazepine na-anabata ya, ya na ndị na-anabata NMDA.

Na mmechi, usoro nke oru ndi ozo nke emebeghi iwu.

Mlọ ọgwụ

Ọgwụ antiepileptik. Ihe owuwu kemịkalụ ahụ yiri GABA, nke na-arụ ọrụ dịka onye ogbugbo breeki na sistemụ akwara. A kwenyere na usoro nke gabapentin dị iche na anticonvulsants ndị ọzọ na-arụ ọrụ site na GABA synapses (gụnyere valproate, barbiturates, benzodiazepines, GABA transaminase inhibitors, GABA uptake inhibitors, GABA agonists and GABA prodrugs). Na nyocha nke vitro egosiwo na ọnụnọ nke saịtị peptide ọhụrụ na-ejikọ aka na akwara ụbụrụ, gụnyere hippocampus na cerebral cortex, nke nwere ike metụtara ọrụ anticonvulsant nke gabapentin na usoro ya. Nnukwu ọnụnọ ndị metụtara ọdịnihu anaghị egbochi ọgwụ ọgwụ ndị ọzọ na ndị na-anabata neurotransmitter na ụbụrụ, gụnyere ya na GABAA-, GABAB-, benzodiazepine na-anabata ya, ya na ndị na-anabata NMDA.

Na mmechi, usoro nke oru ndi ozo nke emebeghi iwu.

Mlọ ọgwụ

Gabapentin na-arahụ n’agha ahụ. Mgbe ingestion nke Cmax gabapentin na plasma na-enweta mgbe awa 2-3 gachara bioavailability zuru oke bụ ihe dịka 60%. N'ikuku n'otu oge nri (gụnyere ndị nwere nnukwu abụba) anaghị emetụta ọgwụ ọgwụ nke gabapentin.

Gabapentin adịghị ejikọ ya na protein ndị dị na plasma ma nwee Vd nke 57.7 L. N'ime ndị ọrịa nwere ọrịa akwụkwụ, ndọta nke mmiri n'ihupentin n'ime mmiri cerebrospinal bụ 20% nke plasma Css kwekọrọ na njedebe nke etiti dosing.

Ọ bụ nanị akụrụ na-ewepụta Gabaptiin. Onweghi ihe iriba ama banyere ndu aru nke aru mmadu. Gabapentin adịghị akpali oxidases na-emetụta metabolism nke ọgwụ. Egosiputara izipu kachasi nma bu ihe eji eme ihe. T1 / 2 bụ sọlfọ na-akwụghị ọtọ ma na-enwe nkezi awa 5-7.

Mwepu nke Gabapentin na-ebelata na ndị agadi na ndị ọrịa nwere ọrụ ezumike ọrụ na-arụ ọrụ nke ọma. Ọnụego mgbanwo mgbe nile, mkpochapụ na mkpochapu nke golfinhu n'ụzọ kwekọrọ na mkpocha nke creatinine.

E wepụrụ Gabapentin na plasma site na hemodialysis.

Ikike Plasma n'ihu ụmụaka dị ka ndị okenye.

Jiri n’oge ime

Ọ ga - ekwe omume n’oge afọ ime naanị ma ọ bụrụ na ihe a tụrụ anya na ọgwụgwọ ga - akarịrị n’ihe nwa ebu n’afọ (emebeghị nyocha dị mma na ụmụ nwanyị dị ime).

Usoro FDA maka ime nwa ebu n’afọ bụ C.

N'oge ọgwụgwọ, a ga-akwụsị ịfeụ ara (tupu ya emee ya mmiri ara, a na -eme ya ọnụ).

Nsonaazụ

Site n'akụkụ nke sistemụ akwara na akụkụ ụjọ: amnesia, ataxia, ndagwurugwu, nsogbu nke mmegharị, ịda mba, ọgbụgba, dysarthria, oke iwe ọgbụgba, nystagmus, iro ụra, iche echiche, ịma jijiji, ịma jijiji, amblyopia, diplopia, hyperkinesia, njọ, adịghị ike ma ọ bụ ike ọgwụgwụ. enweghị mgbanwe, paresthesia, nchekasị, ibu iro, enweghị isi.

Site na usoro nri: mgbanwe dị na ntachi ezé, afọ ọsịsa, agụụ iri nri, ọnụ akọrọ, ọgbụgbọ, ọgbụgbọ, flatulence, anorexia, gingivitis, mgbu afọ, pancreatitis, mgbanwe na ule ọrụ imeju.

Site na sistemụ hemopoietic: leukopenia, mbelata ụbara ọbara ọcha, thrombocytopenic purpura.

Site na usoro iku ume: rhinitis, pharyngitis, ụkwara, oyi baa.

Site na usoro akwara: myalgia, ogbu na nkwonkwo, ọkpụkpụ na-agbaji.

Site na usoro obi: ọbara mgbali elu, ngosipụta nke vasodilation.

Site na usoro urinary: ọrịa urinary tract, urinary incontinence.

Mmeghachi omume nfụkasị: erythema multiforme, Stevens-Johnson syndrome.

Mmeghachi omume akpụkpọ anụ: maceration nke anụ ahụ, ọnya afọ, itching, ihe ọnya.

Ndị ọzọ: mgbu azụ, ike ọgwụgwụ, ọrịa akụkụ, enweghi ume, asthenia, ọrịa, ihu nke ihu, oke ibu, trauma na mberede, asthenia, oria di ka oria, mgbanwe nke akpịrị ọbara, na ụmụ - ọrịa nje, nje otitis media.

Usoro onunu ogwu na nhazi

N'ime, n'agbanyeghị nri.

Postherpetic neuralgia: n’ụbọchị mbụ nke ọgwụgwọ - 300 mg / ụbọchị otu ugboro, n’ụbọchị nke abụọ - 1600 mg / ụbọchị (n’ime usoro abụọ kewara), n’ụbọchị nke atọ 900 mg / ụbọchị (n’ime usoro atọ kewara). Ọ bụrụ na ọ dị mkpa, iji belata ihe mgbu na ọgwụ na-esote, ị nwere ike ịbawanye ya na 1800 mg / ụbọchị (na usoro atọ kewara).

Akwụkwụ na-adọ (dị ka ngwa ọzọ): maka ndị ọrịa karịrị afọ iri na abụọ - 900–1800 mg / ụbọchị (na usoro 3). Ọgwụ izizi bụ 300 mg ugboro atọ n'ụbọchị, ọ bụrụ na ọ dị mkpa, mee ka ọ̀ba ahụ ruo 1800 mg / ụbọchị. Dosebọchị kwa ụbọchị ekwesịghị gafere 3600 mg. 3mụaka 3-12 gbara afọ - ọgwụ izizi nke 10-15 mg / kg / ụbọchị (na usoro 3), a na-ahọrọ mkpụrụ ọgwụ dị irè site na titration maka ụbọchị 3.

Maka ụmụaka gbara afọ 5 ma ọ bụ karịa, ọgwụ dị irè bụ 25-35 mg / kg / ụbọchị, maka ụmụaka 3-4 gbara afọ - 40 mg / kg / ụbọchị (na usoro atọ kewara).

Ogologo oge dị n'etiti doses ekwesịghị gafere awa iri na abụọ.

Nwepu nke gabapentin na / ma obu mgbakwunye nke ọgwụ anticonvulsant ọzọ na ọgwụgwọ a ga-eji nwayọ were ihe dị ka izu 1.

N'ime ndị ọrịa (ihe karịrị afọ iri na abụọ) nwere nsogbu akụrụngwa arụrụala (nwechapụ ihe na-erughị 60 ml / min) ma ọ bụ ndị ọrịa na-anata ọgwụgwọ hemodialysis, a na-ebelata ọ̀tụ̀tụ̀ ahụ ji agbago. Na mwepu nke opekata mpe, 60 ml / min - 900 - 3600 mg / ụbọchị, na mkpochapụ nke 30-55 ml / min - 400-100 mg / ụbọchị, 15-29 ml / min - 200-700 mg / ụbọchị, erughị 15 ml / min - 100-300 mg / ụbọchị. Maka ndị ọrịa ịba n'ọbara, agbakwunye ọzọ post-hemodialysis bụ 125-350 mg mgbe emume hemodialysis anọ gachara.

Mmekọrịta na ọgwụ ndị ọzọ

Mmekọrịta mmekọrịta dị ukwuu n'etiti gabapentin na ọgwụ anticonvulsants ndị ọzọ (phenytoin, valproic acid, phenobarbital, carbamazepine), yana ọgwụ mgbochi nwere norethisterone na / ma ọ bụ etinyl estradiol.

Ihe anakpo Antacids belatara bioavailability nke gabapentin (na omumu mgbe ejiri Maalox were, belata bioavailability nke gabapentin belatara 20%, mgbe ewere 2 awa mgbe o buchara Maalox, 5%).

Cimetidine belata ntakịrị ihe na-eme na-aga n'ihu.

Naproxen (na onodu ogwu nke 250 mg), odi ka odi, a na - abawanye nnabata nke gabapentin (na nha nke 125 mg) site na 12 ruo 15%. Gabapentin anaghị emetụta ọgwụ ọgwụ naproxen. Achọghị mmekọrịta dị n'etiti ọgwụ ndị a na usoro ọgwụgwọ akwadoro.

Morphine (60 mg) mgbe ewere ya elekere 2 mgbe ọ takingụchara gabaptiin (600 mg) mụbara AUC nke gabaptiin site na 44%.

Kpachara anya maka iji ya

Ekwesighi inye ndị ọrịa na-erubeghị afọ iri na abụọ ọrụ izizi Gibepentin (mana enwebeghị ọmụmụ ihe). Edinyere ịdọ aka na ntị maka ndị agadi (ọ nwere ike ịdọpụta akụrụ gbasara akụrụngwa afọ, usoro atọrọ dịka usoro doro anya nke creatinine).

Ka ị na-a gabaụ mmiri dị n'ihu, ekwesighi ịnya ụgbọ ala ma jiri akụrụngwa ọkaibe nke chọrọ itinye uche gị niile.

Ntụziaka pụrụ iche maka nnabata

Mgbe ejikọtara ya na morphine, ọ dị mkpa ịchịkwa mmetụta ọ bụla na-apụta site na sistemụ akwara ozi. A na-eji nwayọ belata ọgwụ nke n'ihupentin na morphine.

Ekwesịrị iwere Gabapentin tupu elekere 2 ka ọ takingụchara ọgwụ antacid.

Mgbe ị na-ekpebi protein na mmamịrị site na iji Ames N-Multistix SG, enwere ike ị nweta nsonaazụ ụgha na-ejikọ ya na iji ọgwụ gaba n'ihu na anticonvulsants ndị ọzọ, ya mere, a na-atụ aro iji ụzọ ndị akọwapụtara karị.

Ihe ngosi maka ojiji

Ọgwụ nke ihe nhụjuanya n’akpa okenye n’ime afọ iri na asatọ, monotherapy nke ọdịdọ akụkụ ya na enweghị nnukwu sekọndrị n’ime ndị okenye na ụmụaka karịrị afọ iri na abụọ, dị ka ngwa ọzọ n’ilekọta ihe ọdịdọ ahụ na-enweghị na nke abụọ n’ime ndị okenye na ụmụaka afọ atọ. na okenye.

Omume ọgwụ

Ọgwụ antiepileptik. Ihe owuwu kemịkalụ ahụ yiri GABA, nke na-arụ ọrụ dịka onye ogbugbo breeki na sistemụ akwara. A kwenyere na usoro nke gabapentin dị iche na anticonvulsants ndị ọzọ na-arụ ọrụ site na GABA synapses (gụnyere valproate, barbiturates, benzodiazepines, GABA transaminase inhibitors, GABA uptake inhibitors, GABA agonists and GABA prodrugs).

International Nonproprietary Aha

INN Medicine - Gabapentin.

Egyptpentin (aha mba Gabaebin) bụ ọgwụ eji agwọ ọrịa Akwụkwụ na-akpọrọ ya na nnukwu ihe ọdịdọ na-esochi ya.

Na nhazi ọkwa mba ụwa nke ATX, ọgwụ nwere koodu N03AX12.

Weputara udi ya na ihe mebere ya

Mmetụta ọgwụ na-enweta nsonaazụ site na ntinye nke gabapentin na ọgwụ a. Na mgbakwunye, ihe mejupụtara ọgwụ ahụ gụnyere povidone, poloxamer, crospovidone, magnesium stearate, hydrolase.

Ọgwụ a dị n'ụdị capsules, nke ọ bụla gụnyere ma ọ dịkarịa ala 300 mg nke ihe ndị na-arụ ọrụ. A na-akwakọ akwa Capsules na blisters nke pcs iri abụọ. Enwere ike ịgbachi blisters 3 ma ọ bụ 6 n'ime igbe kaadi.

Etu esi ewere egipentin?

O bu n'uche ogwu a ka a na-achi. A na-ahọrọ usoro usoro usoro onunu ogwu na-eburu n'uche ogo ngosipụta nke ọrịa. N'ọtụtụ oge, ọnụọgụ 300 ruo 600 mg kwa ụbọchị zuru ezu iji belata mgbaàmà. Ọ bụrụ na ọ dị mkpa, enwere ike ịbawanye ya ruo 900 mg kwa ụbọchị.

Cakpachapụ anya, a ga-eji ọgwụ mee ihe ma ọ bụrụ na mmụba n'ọrụ arụsị bụ nsị nke ụbụrụ na-akpata mkpaghasị.
O bu n'uche ogwu a ka a na-achi.
Ọgwụgwọ ndị ọrịa na-arịa ọrịa shuga mellitus, n'ọtụtụ oge, a na-arụ na mbelata.

Site na anụ ahụ na akwara

Iji Egiptiin nwere ike bute nkwonkwo mgbu. N'ọnọdụ ndị a na-adịghị ahụkebe, megide nzụlite nke ị theụ ọgwụ, a na-ahụ ọdịdị nke edema na isi ike nke nkwonkwo, akwara na ọrịa ogbu na nkwonkwo. Na mgbakwunye, ọgwụ a nwere ike ịmepụta ihe ga - eme tupu ihe a emee bursitis, nsị akwara na osteoporosis.

Ọkpụkpụ afọ

Ọkpụkpụ microbiology nke Egyptpentin bụ nke a na iji ọgwụ a na-eme ihe mgbe niile, ọ na-agbasa ịrụ ọrụ nke sistem nri nkịtị. Ọgwụ a nwere ike ibute stomatitis, gastroenteritis, glossitis, esophageal hernia, proctitis, wdg. Ọgwụ nwere ike ịkpalite mmụba nke eriri afọ. Na mgbakwunye, ndị ọrịa na-enwekarị mkpesa nke mgbu afọ.

Ahụhụ Hematopoietic

Site na iji Egiptiin, thrombocytopenia, akara nke anaemia na purpura nwere ike ime.

Iji Egiptiin nwere ike bute nkwonkwo mgbu.
Ọkpụkpụ microbiology nke Egyptpentin bụ nke a na iji ọgwụ a na-eme ihe mgbe niile, ọ na-agbasa ịrụ ọrụ nke sistem nri nkịtị.
Na nloghachi ihe eji eme ihe ndi Egyptpentin, nsogbu nke psychosis nwere ike ime.

Sistemụ akwara Central

Ojiji nke Egiptiin nwere ike kpalite mbelata na mmetụta na ụfọdụ ike n’ọrụ. Na mgbakwunye, akụrụngwa na-arụ ọrụ nke ọgwụ ahụ nwere ike ime ka ahụ mkpọnwụ ihu, ọbara ọgbụgba n'ime ọbara na dysfunction cerebellar. Megide nzizi nke Egiptiin, inwe mmetuta nke anwansi, ihe ijuanya na mwakpo nke psychosis nwere ike ime. Enwere ike imebi echiche ịta ahụhụ, ụra ehihie na ịhazi nsogbu.

Si na akuko obi

Mmepe nke ihe ndị ọzọ ọ ga-eweta site na iwere Egiptiin site na sistem ụbụrụ. N'otu oge ahụ, enwere ihe ize ndụ nke arrhythmia, vasodilation na jumps na ọbara mgbali.

Inweta Egiptiin nwere ike ibute cystitis na nnukwu urinary retention.
Na mgbakwunye, ọgwụ ahụ nwere ike ịkpalite mmepe nke nnukwu akwara ọdịda.
Na ngbanwe nke ị thisụ ọgwụ a, ọdịdị nke mmeghachi omume nfụkasị ahụ, nke a kọwara dị ka ọnya anụ ahụ, ga-ekwe omume.

Na nzụlite nke ị takingụ ọgwụ a, mmeghachi omume nfụkasị ahụ nwere ike ime, nke emere gosipụtara dịka ọnya ọnya na itching, na-eto nke anụ ahụ dị nro. N'ọnọdụ ndị a na-adịghị ahụkebe, a na-ahụ mmeghachi omume anaphylactic.

Jiri n'oge ime na lactation

Ekwuputaghi ịdị irè na nchekwa nke iji ọgwụ n'oge afọ ime na ịrara nwa, yabụ, ọnọdụ ndị a bụ contraindication maka iji Egyptpentin.

Agadi eme agadi abụghị contraindication maka iji ọgwụ, mana ọ chọrọ mmezi dose dabere na ọrụ nke akụrụ.
Enwere ike iji ọgwụ ahụ mee ihe na ọgwụgwọ nke Akwụkwụ na-adọ na ụmụaka karịa afọ 12.
Oge ime na lact bụ ihe mgbochi maka iji Egypt.
Y’oburu na i buru oke Egypt, juo afọ na-egosi.
Egiptiin nwere ike iwelie mmụba nke phenytoin na plasma ọbara mgbe ị na-eji ya.

Mmanya ndakọrịta

Mgbe ị na-eji ọgwụ a, mmanya ekwesịghị ị alcoholụ ya.

Ọgwụ ndị nwere ụdị ọgwụgwọ ahụ gụnyere:

1. Neurontin.
2. Tebantin.
3. Gabagamma
4. Aha ya bụ Convalis.
5. Gabapentin.
6. Katena.
7. Gapantek et al.

Mbadamba Gaba Gabain. Akwụkwụ na-adọ Ikuku nke Machị 16, 2016. HD HD.

Emeputa

Ọ bụ ọgwụ ndị ụlọ ọrụ Iberfar-nke na-emepụta ọgwụ ahụ.

Ihe mejupụtara yiri ya bụ Neurontin.
Dịka ihe ọzọ, ị nwere ike họrọ Tebantin.
Ọ bụrụ na ọ dị mkpa, enwere ike dochie ọgwụ ahụ na Convalis.

Nyocha banyere Egiptiin

Svetlana, onye gbara afọ 32, Oryol

Anọ m na-arịa akwụkwụ kemgbe m bụ nwata. Ọrịa Seizures na-emebu, ma ndị dọkịta tụtụlite ọgwụ ndị ahụ ma kwụsị. Ihe dị ka afọ atọ gara aga, ọ tụụrụ ime ma mụọ nwa. Site na nzụlite a, ọdịdọ maliteghachiri ọzọ. Dọkịta nyere ya Egiptiin. Ji ọgwụ a ọnwa isii. Enwere m afọ ojuju n'ihe si na ya pụta. Ahụghị m nsonaazụ ọ bụla, mana nwayọ ka ọnụ ọgụgụ nke ihe ọdịdọ belatara. N'agbanyeghị eziokwu ahụ na ịnabata ego kwụsịrị, ruo otu afọ ọ nweghị ihe ọdịdọ ahụ.

Grigory, onye gbara afọ 26, Vladivostok

Agbaliri m ọtụtụ ọgwụ iji kpochapụ ọdịdọ akụkụ. Iji ọgwụ Egyptinịa depụtara ya. Ogwu a adighi nma nye m. Site na ụbọchị nlekọta izizi, mmetụta dị na eriri afọ pụtara. Ọrịa mgbu, ọgbụgbọ, na ọnya mere ka m kwụsị ị .ụ ọgwụ.

Mmetụta akụkụ

Site n'akụkụ nke sistemụ akwara na akụkụ ụjọ: amnesia, ataxia, ndagwurugwu, nsogbu nke mmegharị, ịda mba, ọgbụgba, dysarthria, oke iwe ọgbụgba, nystagmus, iro ụra, iche echiche, ịma jijiji, ịma jijiji, amblyopia, diplopia, hyperkinesia, njọ, adịghị ike ma ọ bụ ike ọgwụgwụ. enweghị mgbanwe, paresthesia, nchekasị, ibu iro, enweghị isi.

Site na usoro nri: mgbanwe dị na ntachi ezé, afọ ọsịsa, agụụ iri nri, ọnụ akọrọ, ọgbụgbọ, ọgbụgbọ, flatulence, anorexia, gingivitis, mgbu afọ, pancreatitis, mgbanwe na ule ọrụ imeju.

Site na sistemụ hemopoietic: leukopenia, mbelata ụbara ọbara ọcha, thrombocytopenic purpura.

Site na usoro iku ume: rhinitis, pharyngitis, ụkwara, oyi baa.

Site na usoro akwara: myalgia, ogbu na nkwonkwo, ọkpụkpụ na-agbaji.

Site na usoro obi: ọbara mgbali elu, ngosipụta nke vasodilation.

Site na usoro urinary: ọrịa urinary tract, urinary incontinence.

Mmeghachi omume nfụkasị: erythema multiforme, Stevens-Johnson syndrome.

Mmeghachi omume akpụkpọ anụ: maceration nke anụ ahụ, ọnya afọ, itching, ihe ọnya.

Ndị ọzọ: mgbu azụ, ike ọgwụgwụ, ọrịa akụkụ, enweghi ume, asthenia, ọrịa, ihu nke ihu, oke ibu, trauma na mberede, asthenia, oria di ka oria, mgbanwe nke akpịrị ọbara, na ụmụ - ọrịa nje, nje otitis media.

Ime na lactation

Emebeghị nnyocha omumu ihe omimi ma ghasasie ike na nchekwa nke mmiri zoputin n’oge ime na ara ndi mmadu. Ọ bụrụ na ọ dị mkpa, iji n'oge afọ ime na ịrara nwa kwesịrị iji nlezianya tụọ uru ọgwụgwọ ọrịa nne ga-elebara anya nke nne na o nwere ike ibute nwa ebu n’afọ ma ọ bụ nwa ọhụrụ.

A na-edobe Gabaptiin n’ime mmiri ara. Mgbe ejiri ya n’oge a na-enye nwa ara, o guzobeghi ụdị ihe emeremehuche nwa ọhụrụ.

Mmekorita

Mgbe ejikọtara ya na ọgwụ anticonvulsants ndị ọzọ, a na-akọpụta nsonaazụ nyocha mmamịrị protein dị mma. Iji chọpụta protein dị na mmamịrị ahụ, a na-atụ aro iji ụzọ kachasị akọwapụta nke sulfosalicylic acid.

Site na iji ọgwụ antacids na-eme n'otu oge, nnabata nke gabaptiin site na eriri afọ na-ebelata.

N'iji oge nke iji felbamate eme ihe, mmụba na T1 / 2 nke felbamate ga-ekwe omume.

N'iji oge a, akọwala okwu gbasara ịba ụba nke phenytoin na plasma ọbara.

Jiri na umuaka

E guzobeghị ịdị irè na nchekwa nke ọgwụgwọ maka ọrịa neuropathic n'ime ndị ọrịa na-erubeghị afọ 18.

Ọdịmma na nchekwa nke monotherapy nke gabapentin na usoro ọgwụgwọ nke ihe ọdịdọ dị na ụmụaka na-erubeghị afọ 12 yana usoro ọgwụgwọ ọzọ na-eji gabapentin na usoro ọgwụgwọ nke ihe ọdịdọ n'ime ụmụ na-erubeghị afọ atọ.