Iwu maka iji ọgwụ ọgwụ Neurorubin

Aha Latin: Neurorubine

Ngwakọta ọrụ: Thiamine hydrochloride + Pyridoxine hydrochloride + Cyanocobalamin (Cyanocobalamin + Thiamine hydrochloridum + Pyridoxine hydrochloridum)

Onye na-emeputa ihe: Wepha GmbH (Germany)

Nkọwa gafere na: 02/05/18

Neurorubin bụ nkwanye vitamin dị mgbagwoju anya maka ọgwụgwọ nke ọrịa akwara ozi.

Mwepụta wepụtara ya na ihe mejupụtara

A na-ere Neurorubin n'ụdị ihe ngwọta maka injection na mbadamba mkpuchi.

Ihe ngwọta dị na ampoules iko enyere na igbe kaadiboodu nke 5 am.

Mbadamba mkpuchi nwere dị na blisters (mbadamba 10 ọ bụla), etinye ya na igbe kaadi nke PC abụọ.

Ihe ngosi maka ojiji

Ihe ngosi maka ojiji bu oria ndi a:

• Polyneuropathy na-arịa ọrịa mamịrị.
• Ahụhụ nke akụkụ ahụ ụjọ na neuralgia sitere na nsị na ihe dị iche iche, gụnyere ọgwụ na mmanya.
• Mgbu na-adịghị ala ala na nnukwu polyneuritis na neuritis.

Ngwọta maka ntụtụ

Ejiri ya mee ihe dị ka monotherapy ma ọ bụ na njikọta ọgwụ ndị ọzọ maka ọrịa ndị a:

• Polyneuropathies na-arịa ọrịa mamịrị.
• Neuropathies (gụnyere mpaghara, mmanya na-akpasu ya iwe).
• Neuralgia, gụnyere trigeminal neuralgia na cervicobrachial neuralgia.
• Ọrịa polyneuritis na-adịghị ala ala na ọrịa neuritis nke etiologies dị iche iche.
• Wet na akọrọ nke beriberi (ọnọdụ nke pụtara na enweghị mmiri), vitamin B hypovitaminosis

Ihe ngbanwe

Ihe mgbochi iji mee ihe bu mmanu ndi mmadu mejuputara. Achọghị ihe ngwọta Neurorubin n'oge ịmụrụ nwa na inye nwa ara, yana maka ọgwụgwọ ụmụaka na-erubeghị afọ 16.

Ejiri ọgwụ nke oke akọ oke nye ndị ọrịa na-arịa ọrịa psoriasis. Etuputara ikike a na ikike nke cyanocobalamin ime ka psoriasis nwekwuo ike.

Nsonaazụ

Ojiji Neurorubin nke ọgwụ nwere ike ibute nsonaazụ ndị a:

• Sistemụ akwara na akụkụ akwara: isi, isi ọwụwa, adịghị ike. N’ọnọdụ ndị a na-adịghị ahụkebe, enwere mmetụta nke nchekasị, mgbakasị ahụ na nchekasị. Mgbe ị na-a theụ ọgwụ ahụ na oke doses, ọ ga-ekwe omume ịzụlite akwara neuropathy akụkụ, nke na-apụ n'anya mgbe ịkwụsị ọgwụ ahụ.
• Ọkpụkpụ akụrụngwa: mkpọsa ọbara (nke a hụrụ na ndị nwere ọgwụ mmụọ na akụkụ ọgwụ), tachycardia.
• Usoro digestive: ọgụ nke ọgbụgbọ, mmụba nke enzymes imeju na ọbara, vomiting. N'ime ndị ọrịa nwere ọgwụ mgbochi, ọbara ọgbụgba na-agba ume.
• Ngosiputa ihe anwansị: urticaria, rashes na itching nke anụahụ. Mgbe ị na-a largeụ ọgwụ ọ largeụ largeụ buru ibu, a hụrụ mmepe nke ihe otutu (ihe otutu).
• Ndị ọzọ: cyanosis, ịsụsọ nke ukwuu, edema. Ndị ọrịa na-ata ahụhụ site na hypersensitivity na ọgwụ ahụ nwere ihe ize ndụ nke ịmalite mmeghachi omume anaphylactoid (gụnyere edegharị Quincke). Site na iji parenteral mee ihe na ndị ọrịa nwere vitamin B, a na-enwe ihe mgbawa ụjọ.

Omume ọgwụ

Neurorubin bụ nkwanye vitamin dị mgbagwoju anya nke nwere vitamin B na-agbanye mmiri .. O nwere ọtụtụ ọrụ ndu.

Vitamin B1 na-etinye aka na metabolism metabolism, na nbibi na transamination nke amino acid, si otú a na-ahazi metabolism protein. Na metabolism abụba, vitamin B1 na-edozi nguzobe nke acid ma buru oke ntụgharị nke carbohydrates na abụba. Activedị vitamin nke na-arụ ọrụ na-akpali motility eriri afọ na ọrụ nzuzo. Vitamin B1 na-eme ka ụzọ ion dị na membranes cell nke neurons, na-emetụta ụzọ nke mkpali dị n'ụdị akwara.

Vitamin B6 na-ekere òkè na njikọ nke enzymes, protein na metabolism abụba, na-ekere òkè n'ọtụtụ mmeghachi omume enzymatic na ọrụ nke coenzyme. Ọ na-achịkwa njikọ nke neurotransmitters na synapses nke etiti na akụkụ nsogbu, na-esonye na nguzobe nke myelin akpụkpọ ahụ nke neurons, na lipid na protein metabolism, na-edozi njikọ nke haemoglobin.

Vitamin B12 na-arụ ọrụ dị mkpa na metabolism metabolism, na-achịkwa njikọ nke amino acid, purines na nucleic acid. Ọ dị mkpa maka usoro nkịtị nke myelination neuronal na ịmalite acetylcholine. Na-akwalite ụzọ dị mma isi emetụta akwara ndị ahụ n'akụkụ akụkụ akwara ozi ma mee ka emeghachite akwara akwara ndị ahụ. Cyanocobalamin nwere mmetụta hematopoietic, na-akpali erythropoiesis, na-eme ka hematopoiesis na-adịwanye mma, na-edozi usoro coagulation ọbara, na-enyere aka belata cholesterol n'ime ọbara.

Neurorubin nwere usoro ọgwụgwọ dị elu nke vitamin dị n'elu, nke dị na mgbagwoju anya na-ahazi ọrụ nke sistemụ ụjọ ma mezie lipid, carbohydrate na metabolism metabolism. Ngwakọta nke vitamin B na-enyere aka belata ihe mgbu na neuralgia nke usoro dị iche iche.

Ntụziaka pụrụ iche

Ihe ndị na-arụ ọrụ nke ihe ngwọta na mbadamba nkume na-agafe ihe mgbochi hematoplacental ma banye na mmiri ara. Enweghị ozi banyere nchekwa nke iji n'oge ime na lactation. Yabụ, dọkịta nwere ike ịkọwa ya ma ọ bụrụ na ihe nwere ike ibute nwa ebu n’afọ na-erughị uru a tụrụ anya ya n’aka nne. Ọ bụrụ na ọ dị mkpa ịdepụta ọgwụ n'oge ị na-a breastụ ara, ọ dị mkpa iji dozie okwu banyere ịkwụsị ịkwa akwa.

Mkparịta ụka ọgwụ ọjọọ

Mgbe ejikọtara ọnụ, neurorubin na -ebelata ọgwụgwọ levodopa. Ekwesịrị ịtụle nke a mgbe ị na-agwọ ndị mmadụ ọrịa Parkinson. A na-atụ aro ka ọ zere n'otu oge nke ọgwụ ndị a.

N'iji ihe eji eme ihe siri ike, ogwu a na-akwalite uto nke isoniazid.

Ọgwụ nke nwere antacid na ngwongwo na-ekpuchi ihe na -ebelata mmịcha (nnabata) nke Neurorubin.

N'ihi vitamin B6, nke bụ akụkụ nke nkwadebe, ọ na-enwe ike ibelata ịdị irè nke altretamine mgbe ejikọtara ọnụ.

Ọnụahịa dị na ahịa ọgwụ

Ọnụahịa nke Neurorubin maka ngwugwu 1 na-amalite na 500 rubles.

Nkọwa dị na ibe a bụ ụdị dị mfe nke nkọwapụta ọgwụ ọgwụ. Enyere ozi a maka ebumnuche gbasara ọfụma ọ bụghị ntuziaka maka ọgwụ ịchọrọ onwe gị. Tupu ị usingụ ọgwụ ahụ, ị ​​ga-agakwuru onye ọkachamara ma mara onwe gị na ntuziaka nke onye nrụpụta kwadoro.

Mlọ ọgwụ

Ihe nchekwa vitamin ọgwụ nwere ihe dịka pyridoxine, cyanocobalamin na thiamine. Otu n'ime ihe ndị a chọrọ ka emee ọtụtụ usoro a na-eme n'ime ahụ mmadụ.

Dịka ọmụmaatụ, thiamine bụ onye na-arụsi ọrụ ike na usoro metabolic metụtara abụba na carbohydrates (mana ọ bụghị protein). Enweghi mmiri nkpuru ahihia agha na eme ka inuwanye onodu nke lactate na pyruvic acid. Ngwakọta bara uru a na-akwalite mmerụ mmiri, yana ịmịnye amino acid dị mkpa maka ahụ.

N'ihi usoro ndị a na-eme na ntinye nke thiamine, metabolism metabolism edozila. Ekwesịrị iburu n'uche na mmewere na-eme ka metabolism abụba na guzobe abụba na mgbakwunye, ọ na-akpali ọrụ nke eriri afọ yana motility, na mgbakwunye, vitamin na-emekọrịta mgbidi nke sel n'ime neurons ma na-akpali ọrụ nke ọwa ion.

Pyridoxine, dị ka thiamine, na-arụsi ọrụ ike na abụba na protein metabolism, ma na-ejikọ ya enzymes. Akụkụ a bụ coenzyme na mmepe nke mmeghachi omume enzymatic. Vitamin A na-enye aka ịkpụ mgbidi myelin ma na-ekere òkè na mgbanwe nke lipids na protein, na mgbakwunye, na njikọta nke haemoglobin na neurotransmitters n'ime synapses nke usoro ụjọ ahụ, yana PNS.

Cyanocobalamin dị ezigbo mkpa na metabolism metabolism, n'otu oge ahụ na-edozi mmepụta purines na nucleic acid na amino acid. Vitamin a dị mkpa maka anụ ahụ, n'ihi na ọ na-emetụta mmepụta nke acetylcholine, yana mgbakwunye na usoro nke myelination neural. Ọzọkwa, akụrụngwa a na-emetụta mweghachi nke akwara akwara ma na-akpali mmepe nke mkpali n'ime akụkụ NS.

Vitamin nwere mmetụta hematopoietic, na-achịkwa cholesterol ma n'otu oge ahụ na-akpali usoro nke erythropoiesis. Cyanocobalamin na-enyere aka melite usoro mgbochi hematopoietic ma mee ka ọnụego ọbara na-esikwusi ike.

Na njikọta, vitamin niile a dị n’elu na-enyere aka kwalite ọrụ nke NS ma n’otu oge ahụ nwee mmetụta dị mma na metabolism nke lipids nwere protein, carbohydrates na abụba.

Ọ dịkwa mkpa iburu n'uche eziokwu ahụ bụ na ụdị vitamin dị otú a na-ebelata oke ihe mgbu na-esite na ọrịa akwara ozi nwere etiology dị iche iche.

, ,

Mlọ ọgwụ

A na-etinye vitamin na-agbanye mmiri kpamkpam mgbe mmiri abanye, ihe ndị ọzọ dị na pharmacokinetic:

• vitamin b₁: Nha nke thiamine gbarie agbasara na enterohepatic mgbasa nke bile acid. Na-agbanweghi agbanwe, thiamine dị ntakịrị, na-abụkarị nke ụdị metabolites: thiamincarboxylic acid na pyramine (2,5 dimethyl-4-aminopyrimidine),
• vitamin b₆: pyridoxine dị n’ime ahụ ka ọ bụrụ pyridoxamine ma ọ bụ oxidized ka pyridoxal; dị ka coenzyme, ọrụ pyridoxine dị ka pyridoxal-5-phosphate (PALP) nke sitere na phosphorylation nke CH₂Otu OH nọ n'ọkwa nke ise, ihe ruru 80% PALF na-ejikọ protein protein, pyridoxine n'ụdị PALF na-agbakọ tumadi na anụ ahụ, nke kachasị na ụdị 4-pyridoxic acid,
• vitamin b₁₂: mgbe a gbasịrị, cyanocobalamin na serum na - ejikọ protein dịkarịsịrị iche na - ụdị B₁₂-bigide β-globulin (transcobalamin) na B₁₂-bigide α1-globulin, a na-enweta vitamin B₁₂ nke kachasị n’ime imeju, ọkara ndụ (T_1/2) ọbara ọbara

Daysbọchị 5, na site na imeju

Mmekorita

A naghị atụ aro ka ị chikọta neurorubin, Levodopa na Altretamine, ebe ọ bụ na vitamin vitamin na-ebelata ịdị irè nke ọgwụ ndị a dị n'elu. Iji zere mmụba nke egbu egbu Isoniazid ejikwala ọgwụ a na ihe mgbagwoju anya n'otu oge B vitamin.

Ọ dị mma icheta nke ahụ Antagonists Vitamin B1 bụ bekee dịka Fluorouracil, ka thiosemicarbazone. Orkpachara anya Neurorubin Forte Lactab belata ọgwụ ndị nwere Ngwongwo antacidna inye mmetụta envelop.

N'oge ime na lactation

Ebe ọ bụ na data na nchekwa zuru oke nke ọgwụ maka ime na enweghị ụmụ nwanyị na-ete nwa, amachibidoro Neurorubin iji n'oge ndị a. Agbanyeghị, dọkịta na-ahụ maka ịga nwere ike inye nwanyị dị ime ọgwụ vitamin a ma ọ bụrụ na enwere nnukwu ahụike yana naanị na atụmanya na uru ebumnuche ga-adị elu karịa mmerụ ahụ.

Ọ bụrụ na ọ dị mkpa, iji neurorubin n'oge lactationtụrụ aro ịkwụsị inye araka njikọ ahụ meririIhe mgbochi hematoplacental ma gbanwee usoro mmiri ara ehi, nke nwere ike imetụta ọnọdụ ahụike nke nwa ahụ n'ụzọ ọjọọ.

Kedu mgbe a na-edenye ọgwụ ahụ

Isi ihe ngosi maka ojiji:

• Wernicke-Korsakoff syndrome, ọrịa neuropathy na-efe efe na ọrịa ndị ọzọ metụtara ịhoụ oké mmanya,
• gba ọtọ na ụdị akọrọ,
• polyneuropathy na-arịa ọrịa mamịrị.

Dịka akụrụngwa nke usoro ọgwụgwọ adjuvant, a na-eji ya maka:

• nnukwu na ala ala neuritis na polyneuritis,
• cervicobrachialgia na trigeminal neuralgia.

Mgbochi ọgwụ

N'ihe banyere ọgwụ ahụ dị ize ndụ maka ọgwụgwọ nke ndị ọrịa:

1. Ihe mgbochi kachasị na ị theụ ọgwụ bụ uche onye ahụ, ọkachasị vitamin B6.
2. A naghị akwado Vitamin B12 maka ndị nwere ọrịa psoriasis, n'ihi na ọ nwere ike ịkpalite ihe mgbaàmà nke ọrịa ahụ.
3. Ejila ogwu ahu ndi nwanyi di ime na ndi na enye nwa ara. N'ime ihe mgbochi ahụ bụ afọ ụmụaka.

Usoro onunu ogwu na uzo ochichi

N'okwu ndị dị elu, a na-enye ọgwụ Neurorubin otu ampoule intramuscularly kwa ụbọchị iji belata ngosipụta nke ihe mgbu. A na-atụ anya ụdị aghụghọ a na mmalite ọgwụgwọ. Emechaa, a na-enye ndị ọrịa ọgwụ 1-2 ampoules 1-2 ugboro n’izu.

Usoro eji:

1. Jiri ampoule were mee akara. Egosiputara ya dika ntụpọ.
2. Ikwanye nke ọma ka mmiri kesaa.
3. Gbipu isi ngwaahịa dị n’elu akara ahụ.

Ohere nke ịdoụbiga mmanya ókè

Excessiveụ vitamin B6 karịrị akarị na mkpokọta 500 mg ma ọ bụ karịa karịa maka ọnwa 5 nwere ike ibute mmeghachi omume dị ize ndụ. Dodoụbiga mmanya ókè na-esokarị:

• mmeghachi omume nfụkasị
• akụkụ ihe ndọghachi azụ akwara ozi.

Neuropathy na-agbakarị mgbe ọ kwụsịsịrị ọgwụ.

Mmeghachi omume ọjọọ

Akingụ ọgwụ ahụ nwere ike isonyere ụdị mmetụta ndị a:

1. Usoro endocrine: mgbochi nke iji prolactin eme ihe.
2. Sistemụ Na - ahụkarị Ọdịmma - ụdị nke ụdị polymorphic erythema, angioedema, njirimara bụ maka ndị nwere ọgụgụ isi na akụkụ nke ọgwụ. Site n'oge ụfọdụ, mgbe ogwu ogbugba intramuscular nke intramuscular, o nwere ike bụrụ ujo anaphylactic. Usoro ọgwụgwọ Symptomatic gụnyere iji ọgwụ antihistamines.
3. Ọkpụkpụ akwara: ọrịa ụkwara ume ọkụ na-eme na ndị nwere ọgụgụ isi na akụkụ, cyanosis, tachycardia na ọbụna ida.
4. N’akụkụ anụ ahụ: urticaria na itching, nke edepụtara n’otu n’otu n’otu. Ọrịa n’ejere ndị ọrịa enyerela ọgwụ ọgwụ ike. Pyridoxine na-akpalite ọdịdị nke ihe ọhụụ, yana mgbasa nke ọnya na ihu.
5. Mmetụta ndị a na-ahụkarị: adịghị ike, dizziness, sweating.

Ndị ọrịa na-enwekarị obi erughị ala mgbe ha werechara Neurorubin. N'ime ụmụ amụrụ ọhụrụ na-enwe ụkọ vitamin B12, e dekọtara okwu mmeghari ahụ mgbe ọ gwọchara ya.

Analogues nke ọgwụ

Site na analogues kwesiri ighota ogwu nke nwere otu aha uwa ndi ozo. Ọ dị mkpa ịghọta na tupu iji dochie dochie Neurorubin, ị ga-agakwuru dọkịta gị. Isi analogues:

1. Vitaxon. Ejiri ụkọ vitamin B1 na B6 dị irè megide ọrịa nke akwara ozi.
2. Neurobion. Ejiri ya na ọgwụgwọ nke neuralgia neuralgia, gụnyere trigeminal neuralgia, intercostal neuralgia. N'ime ihe ngosi ndị ahụ bụ radicular neuritis, mgbanwe ndị ọzọ metụtara degenerative megharia nke spain, prosoplegia, ya bụ, ntụpọ ihu.
3. Neuromax. Ọrịa akwara ozi metụtara ụkọ nyocha nke gosiri vitamin B1 na B6.
4. Neuromultivitis. Ọ dị irè maka polyneuropathy, ọrịa nke akwara sitere na ọrịa dị iche iche, neuralgia na neuritis, radiculoneuritis kpatara nhazigharị na ntọala nke spain, ya na ahụ mkpọnwụ nke akwara mkpụrụ ndụ, sciatica, intercostal neuralgia.
5. Nerviplex. N'ime ihe ndị ahụ na-egosi bụ ụkọ vitamin B1, B6, B12, neuropathy mamịrị, intercostal neuralgia, paresis nke akwara ihu, akwara ozi gbasara akwara dị iche iche.
6. Neurobeks. A na-eji ya maka mgbanwe mgbanwe na akwara dị n'akụkụ, ọrịa na-enweghị isi nke mgbanwe na-agbanwe n'ime ahụ n'ihi ọrịa shuga, onye na-efe efe, na mmanya. N'ime ihe ngosi ndị ahụ bụ polyneuropathies, osteochondrosis, sciatica, lumbago, mmerụ ahụ traktị, dystonia ahịhịa. A na-eji ya na usoro ọgwụgwọ nke vitamin B1, B6, hypovitaminosis, na glaucoma. macular degeneration, pruritus nke etiologies dị iche iche.
7. Unigamma Ejiri usoro ọgwụgwọ Symptomatic nke ọrịa akwara ozi sitere na ụzọ dị iche iche. Nke a bụ ezigbo ngwá ọrụ n'ọgụ megide ọrịa degenerative nke ogwurugwu, ọnya cervical syndrome, lumbago.

Ọnụahịa maka ịhapụ ụdị dị iche iche:

1. Enwere ike ịzụta mbadamba mkpụrụ osisi Neurobion chekwara n'ime ọnụọgụ 20 kwa ngwungwu na nkezi 280-300 rubles.
2. A na-erekwa ihe ngwọta maka nsị intramuscular nke 3 ampoules na ngwugwu 3 ml. Ọnụahịa ha gbasara 280 rubles.

Nsonaazụ

• Usoro obi: n'ime ihe dịpụrụ adịpụ - ida, tachycardia, cyanosis,
• Sistem Central ụjọ: ụjọ, ịma jijiji, inwe mmetụta nke "akpụ na akpịrị", nchekasị, ọgbụgbọ,
• Usoro digestive: ọgbụgbọ, ọbara ọgbụgba, oke ọrụ plasma nke aspartate aminotransferase,
• Usoro endocrine: mgbochi nke prolactin excretion,
• Usoro iku ume: akpa ume, ura ume,
• Akpukpo: Akpụ,
• Mmeghachi omume nfụkasị ahụ: itching, urticaria, edere Quincke, ụjọ anaphylactic,
• Ahụ mmadụ n'ozuzu ya: mmetụta nke adịghị ike, ọsụsọ na mberede, hyperemia nke ihu, ahụ ọkụ.

Dodoụbiga ya ókè

Dodoụbiga ihe ókè nke Neurorubin na-ewusi akara dị otú ahụ nke mmetụta ndị na-adịghị mma dị ka arrhythmia, dizzness, convulsions.

Ihe omume ga - ekwe omume bụrụ ihe ndị mejupụtara vitamin B:

• vitamin b₁: n'ihi oke mmiri nke sisamine, mgbe a na-ewere ya na oke doses (karịa 10,000 mg), a na-ebelata udu na-emetụta akwara, na-ekpughe mmetụta curariform,
• vitamin b₆: pyridoxine nwere oke nsí dị ala, mana etu esi eme ya na oke ọnụọgụ (karịa 1000 mg kwa ụbọchị) nwere ike igosipụta mmetụta neurotoxic ruo ọtụtụ ọnwa, mgbe nchịkwa ahụ na-eme kwa ụbọchị nke ihe karịrị 2,000 mg, mmeghachi omume dịka neuropathy na ataxia na nsogbu uche. ọdịdọ ụbụrụ na mgbanwe mgbanwe electroencephalogram, n'ụfọdụ akụkụ, seborrheic dermatitis na hypochromic anaemia.
• vitamin b₁₂: mgbe nchịkwa paịteral nke cyanocobalamin na usoro onunu gafere nke a tụrụ aro, mmeghachi omume hypersensitivity, ụdị ọrịa akwara na eczematous skin rashes hụrụ na obere okwu, ogologo oge iji oke doses nwere ike ime ka ọrụ na - adịghị ike ọrụ nke enzymes imeju, hypercoagulation, mgbu na obi.

Ọ bụrụ na ị na-eche na usoro ọgwụgwọ a tụrụ aro agafewo, ịkwesịrị ịkwụsị iji Neurorubin na, ọ bụrụ na ọ dị mkpa, ọgwụgwọ Symptomatic.