Lisinopril 20mg Nke 20

Nsogbu ọbara ọgbụgba bụ otu n'ime ọrịa a na-ahụkarị n'etiti ndị nọ n'afọ ndụ dị iche iche. Mgbanwe oge na-adịghị ala ala ma ọ bụ nke na-ezighi ezi n'ihe ngosipụta chọrọ ọgwụgwọ na ọgwụ kwesịrị ekwesị. Otu n'ime ọgwụ ndị a bụ Lisinopril, site na ntuziaka maka ojiji nke anyị na-amụta banyere nrụgide ọ ga-eji. Anyị na-atụlekwa ihe contraindications kwesịrị ịtụle tupu ịmalite ọgwụgwọ.

Ntụziaka maka ojiji

N ’ọnọdụ dị a shouldaa ka a ga-ewere lisinopril? Ọgwụ bụ akụkụ nke ACE inhibitor group. Mgbe ị theụsịrị ọgwụ ahụ, vasodilation na-apụta, ya mere egosipụtara ya maka ọbara mgbali elu. Site na ị regularụ ya mgbe niile, ọ na-arụ ọrụ akwara obi na mgbasa ọbara, a na-ewepụ nnu sodium ngafe n'ahụ. Ọgwụ a na -ebilata diastolic na systolic egosi, ebe anaghị emetụta oke mkpụrụobi.

A na-ahapụ ọgwụ ahụ n’ụdị mbadamba ụrọ nwere ọgwụ dị iche iche. Agba nke mbadamba nkume na-adabere na oke nke ihe na-arụ ọrụ. Oroma zuru oke - 2.5 mg, oroma paịlị - 5 mg, pink - 10 mg, ọcha - 20 mg. Ọnụahịa nke Lisinopril bụ 70-200 rubles. dabere na usoro onunu ogwu ya na onu ogugu gi nke di na ngwugwu.

Dị Mkpa! Lisinopril na-abawanye ndụ mmadụ na ọnụnọ ọrịa siri ike nke obi na akwara ọbara, na-akwụsị ịwụpụ akwara mgbe nkụchi obi gasịrị.

Ngwakọta ọgwụ a gụnyere lisinopril dihydrate, dabere na onye nrụpụtara nke mbadamba ahụ nwere ike ịgụnye ihe ndị ọzọ dị iche iche na-enweghị mmetụta ọgwụgwọ.

Ihe ngosi maka ojiji:

• ọbara mgbali elu na ọbara ọgbụgba dị iche iche etiologies,
• infarction myocardial na nnukwu ogbo,
• ọrịa obi na-adịghị ala ala
• mmebi nke usoro ụjọ ahụ n'ihi ọrịa shuga.

Ọgwụ nwere ọtụtụ analogues nke nwere ọgwụgwọ ọgwụgwọ yiri ya ma ihe fọrọ nke nta adịghị iche na ọnụ ahịa - Lysitar, Vitopril, Dapril, Lipril.

Etu esi ewere ọgwụ

Tupu ịmalite ọgwụgwọ na lisinopril, ịkwesịrị ịmụ ntuziaka ka ị ghọta ihe kpatara ọgwụ ndị a ji enyere aka na otu esi ewere ya nke ọma. A na-ewepụ ọgwụ ahụ site na akụrụ, yabụ, ọnụnọ nke ọrịa dị ukwuu nke akụkụ a kwesịrị ịgwa ndị dọkịta tupu ịmalite ọgwụgwọ.

Dị Mkpa! Mmetụta ọgwụgwọ nke ọgwụ ahụ na-apụta na awa, mmetụta na-adịgide adịgide - mgbe usoro ọnwa gasịrị. Ọgwụ a na-arụ ọrụ nwayọ, yabụ ejighị ya dịka enyemaka mbụ maka nsogbu ọbara ọgbụgba.

Lisinopril nwere mmetụta na-adịte aka, ya mere o zuru ezu iji ya otu ugboro n'ụbọchị, ọkacha mma n'ụtụtụ. Jiri mmiri dị ọcha ụọ ọgwụ ahụ. Usoro ọgwụgwọ ọrịa obi na-etolite usoro ọgwụgwọ zuru oke site na ichebara afọ onye ọrịa yana ọnụnọ nke ọrịa na-adịghị ala ala.

Usoro onunu ogwu nke dabere na oria a:

1. Ọrịa mamịrị na-arịa ọrịa shuga - na mmalite ọgwụgwọ, ọ dịghị ihe karịrị 10 mg nke ọgwụ kwa ụbọchị a ga-ewere. Ọ ga - ekwe omume ịbawanye ọgwụ ahụ na 20 mg, mana enwere ike ịme nke a dịka ebe ikpeazụ, ebe enwere ike dị elu nke nnukwu nsogbu.
2. Ọbara mgbali elu, ọbara mgbali dị mkpa - usoro ọgwụgwọ malitere site na mkpụrụ ọgwụ 10 mg. Iji kwado ndị na-egosi nrụgide n'ọkwa nkịtị, ịkwesịrị ị takeụ 20 mg nke ọgwụ kwa ụbọchị. Ihe kachasị nchebe bụ 40 mg.
3. Obi ọgbụgba na - adịghị ala ala - ọgwụgwọ na - ebido n ’ọgwụ mgeri 2.5, kwa ụbọchị 3-5 ka ọ na - abawanye. Usoro kachasị elu kwa ụbọchị bụ 10 mg.

N'oge ọgwụgwọ na Lisinopril, ọ dị mkpa iji nyochaa ndị na-egosi nrụgide oge niile, lelee akụrụ, ma na-emepụtaghachi ọnwụ nke mmiri na nnu. Ọ dị mkpa iji belata mmega ahụ, ọkachasị na oge ihu igwe.

Dodoụbiga ọgwụ ókè bụ obere - na nke a, ọbara mgbali ji mbelata, ikekwe ọnọdụ ujo, mmepe nke nnukwu gbasara akụrụ. Ihe enyemaka mbu bu mmanu mmanu, n’abido mmiri.

Dị Mkpa! Ọgwụ ahụ na-egbochi ịta ụta na nlebara anya, ya mere, ọ dị mkpa ịhapụ ịkwọ ụgbọ ala, ugwu dị elu na ọrụ ala.

Ngwurugwu mgbochi na nsonaazụ ya

Lisinopril na-enyere aka nke ọma na ọbara mgbali elu, mana ọgwụ ahụ nwere ọtụtụ mmetụta. Ọ bụrụ n’ịgbaso usoro onunu ogwu wee rube usoro usoro ọgwụgwọ ziri ezi dị, mgbe ahụ, a gaghị ahụ nsonaazụ ojoo ahụ mgbe ị takingụsịrị ọgwụ ahụ ma ọ bụ wepụ ya n'ime ụbọchị ole na ole.

• mgbu obi, mbelata nke ọbara mgbali elu,
• mgbanwe na ikike,
• nsogbu na usoro digestive na-akpalite ọdịdị nke ọgbụgbọ na ọgbụgbọ,
• mmụba na ESR, mbelata nke ọkwa hemoglobin,
• ụba nitrogen ọdịnaya nke urea na keratin,
• nkwonkwo mgbu
• ike ọgwụgwụ, isi ọwụwa, ike ọgwụgwụ.

Na nmalite ọgwụgwọ mbụ, mmeghachi omume nfụkasị ụdị nke rashes akpụkpọ ahụ nwere ike ime, mgbe ụfọdụ ụbụrụ Quincke nwere ike ime. Ọtụtụ mgbe, ị aụ otu ọgwụ na-ebute ụkwara.

Ihe ndị a na - egbochi contraindications bụ ntinye nke ọgwụ na lactose, ịba ụba ọgwụ ike site na otu ACE inhibitors, angioedema, idiopathic edema. Lisinopril bụ contraindicated n'oge ime n'oge ọ bụla, na ojiji n'oge a na-enye nwa ara ga-ekwe omume naanị ma ọ bụrụ na a kwụsịtụrụ inye nwa ara. Enweghị data a pụrụ ịdabere na ya banyere nchekwa iji ọgwụ eme ihe na ọrịa ụmụaka, yabụ enyeghị ndị nọ n'okpuru afọ 18 iwu.

Utionkpachara anya na n'okpuru nlekọta mgbe niile nke dibịa kwesịrị iwere lisinopril maka ndị agadi, ndị ọrịa mamịrị, ma ọ bụrụ na akụkọ ntolite nke ọrịa akụrụ na-adịghị ala ala, ma ọ bụ nsogbu na mgbasa ọbara.

Anyị nwere ike kwuo n’ezie banyere enweghị ndakọrịta nke Lisinopril na mmanya. N'oge ọgwụgwọ, ihe ọ preparationsụ andụ na nkwadebe nke nwere ethanol ga-ewepụ kpamkpam. Ọgwụ a na - akwalite mmetụta ọjọọ nke mmanya n’ahụ, nke nwere ike ibute mmepe nke nsogbu imeju dị njọ.

Dị Mkpa! Tupu ịmalite Lisinopril maka nrụgide, ọ dị mkpa iji nyocha zuru ezu iji wepu ọnụnọ nke ọrịa akụrụ ma kpochapụ akpịrị.

Lisinopril ma ọ bụ enalapril - nke ka mma?

Lisinopril na-eme ka ọbara mgbali belata karịa, mmetụta ọgwụgwọ na-adịte aka karịa nke enalapril, nke a kwesịrị ị takenụ ugboro abụọ n'ụbọchị. A na-enyefe ọgwụ abụọ ahụ ihe dị ka otu, mana enalapril anaghị emetụta ike ọ nwere nke ọ na-ewepụtakarị imeju na akụrụ.

Diroton ma ọ bụ Lisinopril - nke ka mma?

Ọgwụ ndị ahụ nwere ọtụtụ ihe ha mekọtara - ha ewepụtara ha n’ụdị mbadamba ụrọ nwere ọgwụ nke 5-20 mg, o zuru ezu ị were ha otu ugboro n’ụbọchị, a na-enwe mmetụta na-adịgide adịgide mgbe izu 2-4 gachara. Mana iji nọgide na-arụ ọrụ kachasị mma, dose Diroton kwesịrị ịdị okpukpu abụọ karịa Lisinopril.

E nwere ụfọdụ ọdịiche dị n'etiti contraindications. Ndi mmadu nke nwere ihe o ketara eketa na usem Quincke ekwesịghị iwere Diroton. A machibidoro Lisinopril ịnabata anagide ላክctose. Ma ọ bụghị ya, nsonaazụ ọgwụ ndị ahụ bụ otu ihe.

Lisinopril ma ọ bụ Lozap - nke ka mma?

Ọgwụ abụọ ahụ dị na otu ACE inhibitor, mana Lozap bụ ọgwụ dị oke ọnụ. Edere ya naanị ma ọ bụrụ na onye ọrịa ahụ nweegidesi ike na ọgwụ ndị ọzọ mmefu ego maka ụdị a.

Enwere ike ị drugsụ ọgwụ ọ bụla nwere ọbara mgbali elu naanị mgbe ị nyochachara ọkachamara gbasara akwara - ọgwụ niile nwere ike nwere ọtụtụ ọgwụ na mmetụta. Iji aka onwe ya nke ọbara mgbali elu nwere ike iduga na ngosipụta dị ala karịa nke nwere ike ikwere, coma na nsonaazụ ndị ọzọ dị njọ.

General njirimara. Ngwakọta:

Lisinopril 5 mg ihe eji eme ihe: lisinopril dihydrate kwekọrọ na 5 mg nke lisinopril,
Lisinopril 10 mg ihe eji eme ihe: lisinopril dihydrate kwekọrọ na 10 mg nke lisinopril,
Lisinopril 20 mg ihe eji eme ihe: lisinopril dihydrate kwekọrọ na 20 mg nke lisinopril,
Ndị na-ahụ maka ya: shuga mmiri ara (lactose), steeti ara ehi.

Nkọwa: Mbadamba 5 mg na 10 mg - ọcha ma ọ bụ ihe fọrọ nke nta ka ọ bụrụ ọcha, cylindrical ewepụghị, na bevel. Mbadamba ụrọ 20 mg - ọcha ma ọ bụ ihe fọrọ nke nta ka ọ bụrụ ọcha, cylindrical dị larịị, yana chamfer na ihe ize ndụ.

Ngwá ọgwụ ọgwụ:

Mlọ ọgwụ ACE inhibitor, na-ebelata nguzobe nke angiotensin II site na angiotensin I. Mbelata nke ọdịnaya nke angiotensin II na-eduga na mbelata nke mbuputara nke aldosterone. Na-ebelata mmebi nke bradykinin ma mee ka njikọ nke prostaglandins dịkwuo elu. Na-ebelata ngụkọta akwara vaskụla mkpụkọ, mgbali ọbara (BP), ibulite, nrụgide na mkpụrụ ndụ akwara, na-ebute mmụba olu nkeji oge na ịba ụba nnabata myocardial maka nrụgide na ndị ọrịa nwere nkụchi obi na-adịghị ala ala. Ọ na-eme ka akwara akwara dị elu karịa akwara. A na-akọwapụta ụfọdụ nsonaazụ site na nsonaazụ sistemụ renin-angiotensin. Site n'iji ogologo oge, hypertrophy nke myocardium na mgbidi nke akwara ndị dị n'ụdị resistive na-ebelata. Ọ na - eme ka ọkpụkpụ ọbara na ischemic myocardium dị mma.
Ndị na - egbochi ACE na - eme ka ogologo ndụ dị ogologo na ndị ọrịa nwere nkụda mmụọ obi, na - ebelata ọganihu nke nkụja aka ekpe na-arịa ọrịa na ọrịa mgbe myocardial infarction na-enweghị ngosipụta ọgwụgwọ nke nkụda obi. The antihypertensive mmetụta na-amalite mgbe ihe 6 awa na-adịgide ruo awa 24. Ogologo oge nke nsonaazụ ahụ dabere na dose. Mmalite nke ọrụ bụ mgbe elekere 1. A na-ekpebi nsonaazụ kachasị mgbe awa 6-7 gachara. Site n'ọbara mgbali elu, a na-ahụ mmetụta ahụ na ụbọchị mbụ mgbe ebidochara ọgwụgwọ, mmetụta kwụsiri ike na-amalite mgbe ọnwa 1-2 gachara. Site na ịkwụsị ọgwụ ọgwụ ike, achọpụtaghị mmụba dị elu nke ọbara mgbali.
Na mgbakwunye na iweda ọbara mgbali elu, lisinopril na-ebelata albuminuria. N'ime ndị ọrịa nwere hyperglycemia, ọ na-enyere aka ịdịzie aka ọrụ nke endothelium glomerular mebiri emebi.
Lisinopril anaghị emetụta ịta ọkwa glucose ọbara na ndị ọrịa nwere ọrịa mellitus ma ọ dịghị ebute mmụba na ikpe nke hypoglycemia.

Mlọ ọgwụ Mwepu: Site na nchịkwa ọnụ, ihe dị ka 25% nke Lisinopril na-abanye na eriri afọ. Iri nri anaghị emetụta nnabata nke ọgwụ. Bioavailability bụ 29%.
Nkesa. Ihe fọrọ nke nta ka ọ bụrụ na ejikọtaghị protein ndị dị na plasma. Oke plasma ịta (90 ng / ml) ruru ka elekere asaa gachara. Ikike zuru oke site na ụbụrụ ọbara na ihe mgbochi placental dị ala.
Metabolism. Lisinopril abụghị biotransform na anụ ahụ.
Ojiji. Ọ na-abụpụtara ya akụrụ na-agbanweghi. Nkeji ọkara bụ awa iri na abụọ.
Pharmacokinetics na ụfọdụ ndị ọrịa: N'ime ndị ọrịa nwere nkụchi obi na-adịghị ala ala, a na-ebelata mmịnye na mkpụcha nke Lisinopril.
N'ime ndị ọrịa nwere akụrụ gbasara akụrụngwa, mkpo nke lisinopril dị ọtụtụ oge karịa ịta ụta na plasma ọbara nke ndị ọrụ afọ ofufo, enwere mmụba na oge iji ruo n'ọtụtụ kachasị na plasma ọbara na mmụba na ọkara ndụ.
N'ime ndị ọrịa merela agadi, ịka oke ọgwụ n'ime plasma ọbara na mpaghara dị n'okpuru usoro ahụ ji okpukpu abụọ karịa ndị ọrịa na-eto eto.

Ihe ngosi maka ojiji:

- ọbara mgbali elu (na monotherapy ma ọ bụ yana ọgwụ ndị ọzọ na - egbochi mkpali),
- Ọrịa obi na-adịghị ala ala (dị ka akụkụ nke ọgwụgwọ njikọ maka ọgwụgwọ nke ndị ọrịa na-a digitalụ digitalis na / ma ọ bụ diuretics),
- treatmentgwọ ọrịa n'oge na - arịa nnukwu ọrịa myocardial (n'ime awa iri abụọ na anọ mbụ na - arịa ya ka ọ dị ala iji lekọta ihe ngosi ndị a ma gbochie ụsọ mmụọ na nkụchi obi).
- Nephropathy na-arịa ọrịa shuga (ibelata albuminuria na ndị ọrịa insulin na-enwe nsogbu ọbara nkịtị na ndị ọrịa na-abụghị insulin nwere ọbara mgbali elu).

Usoro usoro onunu ogwu

N'ime, n'agbanyeghị nri. Site n'ọbara mgbali elu, ndị ọrịa na-anabataghị ọgwụ mgbochi ọgwụ ọzọ ka etinyere 5 mg otu ugboro n'ụbọchị. Ọ bụrụ na enweghị mmetụta ọ bụla, a na-amụba dose ahụ kwa ụbọchị 2-3 site na 5 mg gaa na nkezi ọgwụgwọ 20-40 mg / ụbọchị (ịba ụba dose ahụ karịa 40 mg / ụbọchị anaghị ebute mgbada ọbara ọzọ).
Ihe a na-ahụkarị kwa ụbọchị bụ 20 mg. Oke kachasị kwa ụbọchị bụ 40 mg. Nsonaazụ zuru oke na-etolite mgbe izu 2-4 gachara site na nmalite ọgwụgwọ, nke ekwesiri iburu n'uche mgbe ị na-abawanye dose ahụ. Site na nsonaazụ na-ezighi ezi nke ụlọ ọgwụ, ọ ga-ekwe omume ijikọta ọgwụ na ọgwụ ndị ọzọ antihypertensive.
Ọ bụrụ na onye ọrịa ahụ natara ọgwụgwọ mbido site n’ọrịa diuretics, mgbe ahụ, a ga-akwụsị ị intụ ọgwụ ndị ahụ ụbọchị 2-3 tupu mmalite nke Lisinopril. Ọ bụrụ na nke a agaghị ekwe omume, mgbe ahụ ọgwụ mbụ nke Lisinopril ekwesịghị gafere 5 mg kwa ụbọchị. N'okwu a, mgbe ị takingụsịrị ọgwụ nke mbụ, a na-atụ aro ịlele ahụike maka ọtụtụ awa (a na-enweta nsonaazụ kachasị mgbe ihe dị ka awa 6), ebe ọ bụ na mbelata ọbara mgbali elu nwere ike ime.
N'ihe banyere ọbara ọgbụgba ọbara ma ọ bụ ọnọdụ ndị ọzọ na ọrụ na-arịwanye elu nke sistemụ renin-angiotensin-aldosterone, ọ dịkwa mma ịdebere obere mmalite mbụ nke 2.5-5 mg kwa ụbọchị, n'okpuru nlekọta nlekọta ahụike (njikwa ọbara mgbali, ọrụ akụrụ, itinye uche potassium na ọbara ọbara). Ekwesịrị ịhọrọ usoro mmezi ahụ, na-aga n'ihu na nlekọta ahụike siri ike dabere na ogo nrụgide ọbara.
N'ihe banyere ọdịda akụrụ, n'ihi eziokwu ahụ bụ na a na-ekepụta lisinopril site na akụrụ, a ga-ekpebi ụzọ izizi dabere na nhichapụ nke creatinine, mgbe ahụ, dabere na mmeghachi omume, a ga-eguzobe usoro mmezi n'okpuru ọnọdụ nleba anya ugboro ugboro maka ọrụ gbasara akụrụ, potassium, sodium serum Level.

Mepụta mbinye mmiri ml / min Oge mbu mg / ụbọchị
30-70 5-10
10-30 2,5-5
erughị 10 2,5
(gụnyere ndị ọrịa agwọ ọrịa ịba ọcha n'anya)

Site na mgbali elu nke akwara ọbara, a na-egosipụta ọgwụgwọ usoro ogologo oge nke 10-15 mg / ụbọchị.
Na nkụda obi na - adịghị ala ala - bido na 2,5 mg 1 oge kwa ụbọchị, nke na-esote mmụba nke 2,5 mg na ụbọchị 3-5 gaa na nke a na - akwado, kwa ụbọchị nke 5-20 mg. Ọgwụ ahụ agaghị akarị 20 mg kwa ụbọchị.
N'ime ndị agadi, a na-ahụkarị mmetụta hypotensive nwere ogologo oge, nke a na-esonye na mbelata Lisinopril excretion (a na-atụ aro ịmalite ọgwụgwọ na 2.5 mg / ụbọchị).
Nnukwu myocardial infarction (dị ka akụkụ nke ọgwụgwọ njikọ)
N’ụbọchị mbụ - 5 mg n’ọnụ, emesia 5 mg kwa ụbọchị, 10 mg kwa ụbọchị abụọ, mechaa 10 mg otu ugboro n’ụbọchị. N'ime ndị ọrịa nwere nnukwu myocardial infarction, a ga-eji ọgwụ ahụ ọ dịkarịa ala izu isii.
Na nmalite ọgwụgwọ ma ọ bụ n’ime ụbọchị 3 mbụ mgbe ọ gbasasịrị nnukwu ọrịa myocardial infarction na ndị ọrịa nwere ọbara mgbali systolic dị ala (120 mm Hg ma ọ bụ nke dị ala), ekwesịrị ịdebe obere ọgwụ - 2.5 mg. N'ihe banyere mbelata ọbara mgbali (systolic ọbara mgbali n'okpuru ma ọ bụ hara 100 mm Hg), kwa ụbọchị, 5 mg nwere ike, ma ọ bụrụ na ọ dị mkpa, belata oge ruo 2.5 mg. N'ihe banyere mbelata ọbara mgbali ogologo oge (mgbali ọbara systolic n'okpuru 90 mm Hg maka ihe karịrị elekere 1), aga-akwụsị ọgwụgwọ na Lisinopril.
Ọrịa mamịrị na-arịa ọrịa mamịrị.
N'ime ndị ọrịa nwere ọrịa mellitus na-abụghị insulin, a na-eji 10 mg nke Lisinopril otu ugboro n'ụbọchị.Ogwu nwere ike, ọ bụrụ na ọ dị mkpa, ka etinyere ya gaa na 20 mg otu ugboro kwa ụbọchị iji mezuo ụkpụrụ ọbara mgbali elu n'okpuru 75 mm Hg. nọdụ ọdụ. N'ime ndị ọrịa nwere mellitus ọrịa shuga na-akpata insulin, usoro ọgwụgwọ ahụ bụ otu, iji mezuo ụkpụrụ ọbara mgbali elu n'okpuru 90 mm Hg. nọdụ ọdụ.

Njirimara Ngwa:

Hypotension Symptomatic.
Ọtụtụ mgbe, mbelata ọbara mgbali elu pụtara na mbelata nke mmiri na-ebute site na ọgwụgwọ diuretic, mbelata nke oke nnu na nri, ọnya afọ, afọ ọsịsa, ma ọ bụ vomiting. N'ime ndị ọrịa nwere ọrịa obi na-adịghị ala ala nke nwere ezigbo akwara akwara ma ọ bụ na-enweghị ya, mbelata ọbara mgbali elu ga-ekwe omume. A na-ahụkarị ya na ndị ọrịa nwere nnukwu ọrịa obi na-adịghị ala ala, n'ihi ojiji nke nnukwu ọgwụ diuretics, hyponatremia, ma ọ bụ ọrụ ezigharị mkpị. N'ime ndị ọrịa dị otú ahụ, a ga-amalite ọgwụgwọ na Lisinopril n'okpuru nlekọta dọkịta siri ike (iji nlezianya, nhọrọ nke ọgwụ na ọgwụ diuretics).
Ekwesịrị ịgbaso iwu ndị yiri ya mgbe ị na-edepụta ndị ọrịa nwere ọrịa obi, ọrịa ụkọ akwara, nke oke mbelata ọbara mgbali elu nwere ike ibute infarction myocardial ma ọ bụ ọrịa strok.
Mmeghachi azụ hypotensive abụghị ọgwụ mgbochi maka ị theụ ọgwụ ọzọ.
Mgbe ị na-eji Lisinopril na ụfọdụ ndị ọrịa nwere nkụda mmụọ na-adịghị ala ala, mana iji ọbara mgbali nkịtị ma ọ bụ nke dị ala, mbelata ọbara mgbali nwere ike ime, nke na-abụkarị ihe kpatara ịkwụsị ọgwụgwọ.
Tupu ịmalite ọgwụgwọ na Lisinopril, ọ bụrụ na ọ ga - ekwe omume, mee ka mkpesa sodium na / ma ọ bụ mepụta mmiri furu efu, lelee mmetụta mbụ Lisinopril nwere n'ahụ onye ọrịa. N'ihe banyere akwara akwara stenosis (ọkachasị na stenosis nke abụọ, ma ọ bụ ọnụnọ nke akwara akwara), yana ọrịa okirikiri n'ihi sodium na / ma ọ bụ mmiri mmiri, iji Lisinopril nwekwara ike ibute ọrụ akwara na -akpọ, nnukwu akụrụ gbasara akwara, nke na-abụkarị Ọ na-enyo na-enweghị ike ịgbanwe agbanwe mgbe ịkwụsị ọgwụ ọgwụ.
Na nnukwu myocardial infarction:
Egosipụtara iji usoro ọgwụgwọ (thrombolytics, acetylsalicylic acid, beta-blockers). Enwere ike iji Lisinopril mee ihe yana njikọta nke intravenous ma ọ bụ iji usoro ọgwụgwọ transdermal nke nitroglycerin.
Ntinye aka ịwa ahụ / ọgwụ na-akụnwụ ahụ.
Site na mmerụ ahụ dị ukwuu, yana iji ọgwụ ndị ọzọ na-eme ka ọbara mgbali elu belata, Lisinopril, na-egbochi oruru nke angiotensin nke II, nwere ike ibute mbelata ọbara mgbali elu na-enweghị atụ.
N'ime ndị ọrịa merela agadi, otu dose ahụ na-eduga n'ọtụtụ ọgwụ dị elu n'ọbara, yabụ, achọrọ nlekọta pụrụ iche mgbe ị na-ekpebi dose ahụ.
Ebe ọ bụ na enweghị ike iwepụ ihe ize ndụ nke agranulocytosis, a chọrọ nlebara anya oge ihe osise ọbara. Mgbe ị na-eji ọgwụ ahụ eme ihe n’ọnọdụ ọnọdụ akụrụngwa ya na mkpokọ polyacryl-nitrile, ujo anaphylactic nwere ike ime, yabụ, a na-atụ aro ka ụdị ụdị akpụkpọ ahụ dị iche iche wee dialysis, ma ọ bụ nhọpụta nke ndị ọzọ na - egbochi ọgwụ.
Mmetụta ikike ịkwọ ụgbọala na usoro.
Onweghi data na nsonaazụ Lisinopril n'ikike inya ugboala na usoro ejiri na usoro ọgwụgwọ, ma aghaghi iburu n'uche na ochi enwere ike, yabụ ekwesiri ịkpachara anya.

Mmetụta ọghọm:

Nsonaazụ kachasị emetụta: ọgbụgbọ, isi ọwụwa, ike ọgwụgwụ, afọ ọsịsa, ụkwara akọrọ, ọgbụgbọ.
- Site na usoro akwara obi: mbelata ọbara mgbali, obi mgbu, adịghị obere - orthostatic hypotension, tachycardia, bradycardia, ihe na - akawanye njọ nke nkụchi obi, ọrịa ụbụrụ na - akpata isi, myocardial infarction, palpitations obi.
- Site na sistemụ akwara na -akpata: lability ọnọdụ, ọgba aghara, paresthesia, iro ụra, na -eme ka uru ahụ nke aka na egbugbere ọnụ ya, adịghị ike - ọrịa asthenic.
- Site na usoro haemopoietic: leukopenia, neutropenia, agranulocytosis, thrombocytopenia, anaemia (mbelata hemoglobin, hematocrit, erythrocytopenia).
- Ndị na - egosi ụlọ nyocha: hyperkalemia, hyponatremia, adịkarịghị - ụba ọrụ nke enzymes "imeju", hyperbilirubinemia, ụba urea na creatinine.
- Site na sistem iku ume: dyspnea, bronchospasm.
- Site na nri digestive: akọrọ akọrọ, anorexia, dyspepsia, mgbanwe uto, mgbu nke afọ, pancreatitis, hepatocellular ma ọ bụ cholestatic jaundice, ịba ọcha n'anya.
- Site na anụ ahụ: urticaria, ịba ụba ọsụsọ, itching, alopecia, photoensitivity.
- Site na usoro mkpụrụ ndụ: arụ ọrụ akụrụngwa arụrụala, oliguria, anuria, oke gbasara akụrụ oke, uremia, proteinuria, belata ikike. Mmeghachi omume nrịanrịa: angioedema nke ihu, aka, egbugbere ọnụ, ire, epiglottis na / ma ọ bụ nkọlọ, ọnya ọnya, itching, ahụ ọkụ, ezigbo antinuclear antibody test results, ịba ụba erythrocyte sedimentation rate (ESR), eosinophilia, leukocytosis. N'okwu ndị na-adịghị ahụkebe, angioedema interstitial.
- Ndị ọzọ: myalgia, ogbu na nkwonkwo / ọrịa ogbu na nkwonkwo, vasculitis.

Mmekọrịta na ọgwụ ndị ọzọ:

Lisinopril na -ebelata ntụpọ nke potassium site n'ahụ ahụ n'oge ọgwụgwọ ya. Ọ dị mkpa ịkpachara anya mgbe ị na-eji ọgwụ ahụ: potassium-sparing diuretics (spironolactone, triamteren, amiloride), potassium, sodium chloride nọchiri potassium nwere ihe ize ndụ nke ịbawanye hyperkalemia na-abawanye, ọkachasị na ọrụ ezigharị arụmọrụ), ya mere enwere ike ịkọ ha ọnụ naanị na ndabere nke otu nsogbu onye dibia bekee nke n’ileba anya na otutu onodu ogwu ya na aru oru ya.
Enwere ike itinye mgbakwunye ọnụ:
- ya na diuretics: ya na njikwa nke diuretic na onye ọrịa na - ewere Lisinopril, dị ka a na-achị, ihe mgbakwunye antihypertensive na - apụta - ihe egwu nke mbelata ọbara mgbali elu,
- na ihe ndị ọzọ na - eme ihe na - egbochi ihe (mmetụta mmụba),
- na ọgwụ mgbochi mkpali na - abụghị steroidal (indomethacin, wdg), estrogens, yana adrenostimulants - mbelata na antihypertensive mmetụta nke Lisinopril,
- na lithium (ikuku lithium nwere ike ibelata, yabụ, a ga-enyocha nlebara lithium anya),
- na antacids na colestyramine - belata mmụba na eriri afọ. Mmanya na-abawanye nsonaazụ nke ọgwụ.

Contraindications:

Hypersensitivity na Lisinopril ma ọ bụ ndị ọzọ na-egbochi ACE, akụkọ ihe mere eme nke angioedema, gụnyere ojiji nke ACE inhibitors, Heiniti Quincke edema, na-erubeghị afọ 18 (arụpụtaghị ikike na nchekwa).

Na mkpachapụ anya: nnukwu nsogbu gbasara akụrụ, ọnya akwara akwara ma ọ bụ stenosis nke otu akụrụ akwara na-enwe ọganihu azotemia, akụrụ gbasara akwara, ọdịda akụrụ, azotemia, hyperkalemia, stenosis nke aortic orifice, hypertrophic obstructive cardiomyopathy, ọbara mgbali elu, ọbara mgbali, gụnyere ọrịa ụbụrụ), akwara obi, ọrịa obi, ụkwara ume ọkụ, ọrịa sistem ọrịa anụ ahụ jikọrọ ọnụ (gụnyere scleroderma, system lupus erythematosus), mgbochi nke ụmị ọkpụkpụ, nri na-egbochi mgbochi sodium: ọnọdụ hypovolemic (gụnyere n'ihi afọ ọsịsa, ọgbụgbọ).
Jiri n'oge ime na lactation. Ngwa: Lisinopril n'oge afọ ime ka egbochi ime. Mgbe etinyere ime, ekwesịrị ịkwụsị ọgwụ a ozugbo enwere ike. Nnabata nke ndị na - egbochi ACE na ngụkọ oge atọ nke III nwere afọ ojuju na nwa ebu n’afọ (mbelata ọbara mgbali, ọdịda akwara, hyperkalemia, hypoplasia skull, ọnwụ intrauterine). Enweghị data na mmetụta ọjọọ nke ọgwụ ọjọọ na nwa ebu n'afọ ma ọ bụrụ na ejiri ya n'oge ọnwa atọ. Maka ụmụ amụrụ ọhụrụ na ụmụ aka amụrụ ihe na-ebute intrauterine n’ebe ndị na-egbochi ACE, a na-atụ aro ka ejiri nlezianya nyochaa anya oge ịchọpụta mbelata ọbara mgbali elu, oliguria, hyperkalemia.
Lisinopril na-agafe Plasenta. Enweghị data na ntopute nke lisinopril n'ime mmiri ara. Ruo oge ọgwụgwọ ọgwụ ahụ, ọ dị mkpa ịkagbu ara.

Dodoụbiga ya ókè

Mgbaàmà (na-eme mgbe ị na-ewere otu ọgwụ nke 50 mg ma ọ bụ karịa): mbelata ọbara mgbali elu, akpọnwụ akpịrị, ụra, njide urinary, afọ ntachi, nchekasị, ụba iwe. Ọgwụgwọ: usoro ọgwụgwọ ọgbụgba, nchịkwa mmiri ọmụmụ, njikwa ọbara ọgbụgba, nguzo mmiri-electrolyte na nhazi nke ndị ikpeazụ.
Enwere ike wepu Lisinopril site na anụ ahụ site na ị nweta ọgwụgwọ metụtara anụ ahụ.

Ọnọdụ ezumike:

5, 10 ma ọ bụ 20 mg mbadamba. Mpempe akwụkwọ 10 kwa iko na-acha uhie uhie nke ihe nkiri polyvinyl chloride na aluminom foil, mbadamba 20 ma ọ bụ 30 na iko iko mkpuchi ma ọ bụ na polymer nwere ma ọ bụ na karama polymer, nke ọ bụla nwere ike ma ọ bụ karama, ma ọ bụ 1, 2 ma ọ bụ 3 blister ngwakọta yana ntuziaka maka ojiji tinye ya na ngwugwu kaadiboodu.