Protaphane® HM (Protaphane® HM)

Ọrịa hypoglycemic, insulin na-arụ ọrụ.
Nkwadebe: PROTAFAN® NM
Ọrụ umi nke ogwu: mwepu insulin nke mmadụ na-egbochi
Ihe ntinye ATX: A10AC01
KFG: Ogologo Ogologo Nnyocha Ọgwụ mmadụ
Reg. nọmba: P Nke 014722/01
Registrationbọchị ndebanye: 04/20/07
Ndi nwe reg. acc:: NOVO NORDISK A / S

Leasehapụ wepụtara Protafan nm, nnabata ọgwụ na ihe mejupụtara.

Nkwụchi nke sc nchịkwa nke agba ọcha, mgbe ọ mebiri, na-etisa ọcha na ụcha ma ọ bụ ihe na-enweghị isi, na-akpali akpali, a ga-eweghachi iweghachi ihe.

1 ml
isofan insulin (inyocha mkpụrụ ndụ ihe nketa mmadụ)
100 IU *

* 1 IU dabara na 35 μg nke insulin na-eme mmadụ.

10 ml - karama nke iko na-enweghị ụcha (1) - ngwugwu nke kaadiboodu.

NWAANYI NIILE ANYA.
A na-egosi ozi niile enyere naanị maka ịmara ọgwụ ahụ, ị ​​kwesịrị ịkpọtụrụ dọkịta maka ohere eji ya.

Ulo ogwu Protafan nm

Ihe nnọchianya nke inspoglycemic, insulin na-arụ ọrụ nke enwetara site na usoro mkpụrụ ndụ ihe nketa, bụ insulin mmadụ.

Withme ka otu onye nnabata nke akpụkpọ ahụ dị na sel na - emekọ ihe, na - eme ka ihe nnabata nke insulin. Site na ịba ụba njikọta nke cAMP (na abụba abụba na akwara akwara) ma ọ bụ banye n’ime sel (akwara), insulin receptor complex na-akpali usoro intracellular, gụnyere njikọ nke ọtụtụ enzymes isi (gụnyere hexokinase, pyruvate kinase, glycogen synthetase).

A na-eme ka mbelata glucose na ọbara na-abawanye site na mmụba na ntinye ya na intracellular, nnabata nke ukwuu na nro nke anụ ahụ, mkpali nke lipogenesis, glycogenogenesis, njikọ protein, yana mbelata nke mmịpụta nke glucose site na imeju (ibelata na mmebi nke glycogen).

Pharmacokinetics nke ọgwụ.

Mwepu na mmalite nke ihe ahụ dabere n'okporo ụzọ nchịkwa (sc ma ọ bụ intramuscularly), ọnọdụ (afọ, apata ụkwụ, isi) na olu ịgba ọgwụ, ịta insulin na ọgwụ. A na-ekesasị ya na akwara na - ekwekọghị n ’ụzọ anụ ahụ, ọ banyeghị n’ihe mgbochi placental ma banye n’ime mmiri ara. Insulinase bibiri ya, ọkachasị na imeju na akụrụ. Ọ bụ ya bụ akụrụ (30-80%).

Usoro onunu ogwu na uzo icho ogwu a.

Tinye s / c, 1-2 ugboro / ụbọchị, nkeji 30-45 tupu nri ụtụtụ. Ekwesịrị ịgbanwe saịtị nsị ahụ oge ọ bụla. N'ọnọdụ ndị pụrụ iche, ntinye okwu / m ga-ekwe omume.

Anabataghị / na iwebata insulin nke ọkara oge.

A na-edowe doses n'otu n'otu, dabere na ọdịnaya nke glucose dị n'ọbara na mmamịrị, njirimara nke ụzọ ọrịa ahụ.

Mmetụta uto nke Protafan nm:

Mmeghachi omume n'ihi nsị metabolism: hypoglycemia (pallor nke anụ ahụ, ịba ụba ọsụsọ, palpitations, ịma jijiji, agụụ, oke iwe, paresthesia n'ọnụ, isi ọwụwa). Nnukwu hypoglycemia siri ike nwere ike iduga mmepe nke hypoglycemic coma.

Mmeghachi omume nfụkasị: ọ na - adịkarịghị nro anụ ahụ, isi mkpịsị Quincke, n'ọnọdụ ụfọdụ - ujo anafilactic.

Mmeghachi omume mpaghara: hyperemia, ọzịza, itching, na iji ogologo oge - lipodystrophy.

Ndị ọzọ: edema, njehie na - ebugharị ebumnuche (ọ na - abụkarị mmalite nke ọgwụgwọ).

Jiri n'oge ime na lactation.

N'oge afọ ime, ọ dị mkpa iburu n'uche mbelata mkpa nke insulin na ọkara nke mbụ ma ọ bụ mmụba nke ọnwa nke abụọ na nke atọ. N'oge na mgbe amuchara nwa, ihe ndi choro insulin nwere ike igbadata nke ukwuu.

N'oge a na-enye nwa ara, a na-achọ nlele kwa ụbọchị ruo ọtụtụ ọnwa (ruo mgbe a gbanwere mkpa insulin).

Ntụziaka pụrụ iche maka iji Protafan nm.

N'iji nlezianya mee ihe, a na-ahọrọ ọ̀gwụ nke ọgwụ ahụ na ndị ọrịa nwere ọrịa ụbụrụ n'oge gara aga dịka ụdị ọrịa ischemic dị na ya na ụdị ọrịa obi ischemic siri ike.
Mkpa insulin nwere ike ịgbanwe n'ọnọdụ ndị a: mgbe ị na-agbanwe ụdị insulin ọzọ, mgbe ị na-agbanwe nri, afọ ọsịsa, vomiting, mgbe ị na-agbanwe olu arụmọrụ nkịtị, na ọrịa nke akụrụ, imeju, pituitary, gland thyroid, mgbe ị na-agbanwe ebe nsị.
Requiredme mgbanwe insulin kwa ụfọdụ maka ọrịa na-efe efe, nsị thyroid, ọrịa Addison, hypopituitarism, ọdịda akụrụ na-adịghị ala ala, yana ọrịa mellitus na ndị ọrịa karịa afọ 65.

Thegbanwe onye ọrịa na insulin mmadụ kwesịrị ịbụ nke ziri ezi mgbe niile ma mekwa ya naanị n'okpuru nlekọta dọkịta.

Ihe kpatara hypoglycemia nwere ike ịbụ: insulin overdose, ọgwụ iji ọgwụ eme ihe, ite mmiri, vomiting, afọ ọsịsa, nchekasị anụ ahụ, ọrịa ndị na-ebelata mkpa insulin (ọrịa akụrụ na ọrịa imeju, yana hypofunction nke adrenal cortex, pituitary ma ọ bụ thyroid gland), mgbanwe nke ebe ịgba. (dịka ọmụmaatụ, anụ dị n’afọ, ubu, apata ụkwụ), yana ịmekọrịta ọgwụ ndị ọzọ. O kwere omume belata mkpụkọ glucose dị n'ọbara mgbe ị na-ebufe onye ọrịa site na insulin anụmanụ n'ime insulin nke mmadụ.

Ekwesịrị ịgwa onye ọrịa banyere ihe mgbaàmà hypoglycemic ala, banyere ihe ịrịba ama mbụ nke ọrịa mamịrị na banyere mkpa ọ ga-agwa dọkịta banyere mgbanwe niile na ọnọdụ ya.

N'ihe banyere hypoglycemia, ọ bụrụ na onye ọrịa maara, a na-edenye ya dextrose n'ime, s / c, iv ma ọ bụ iv glucose glucagon ma ọ bụ iv hypertonic dextrose solution. Site na ntinye nke hypoglycemic coma, 20-40 ml (ihe ruru 100 ml) nke mmiri 40% dextrose na-abanye n'ime iyi ruo mgbe onye ọrịa ahụ si na Coma pụta.

Ndị ọrịa nwere ọrịa shuga nwere ike ịkwụsị ntakịrị hypoglycemia nke ha na-enwe site na iri shuga ma ọ bụ nri dị oke na carbohydrates (a na-atụ aro ka ndị ọrịa nwee mgbe ọ dịkarịa ala 20 g sugar).

Mbelata mmanya na-egbu egbu n'ime ndị ọrịa na-anata insulin.

Mmetụta ikike ịkwọ ụgbọ ala na usoro nchịkwa

Omume nke ịmalite hypoglycemia nwere ike imebi ikike nke ndị ọrịa ịnya ụgbọ ala ma jiri usoro rụọ ọrụ.

Nmekorita nke Protafan nm na ogwu ndi ozo.

Mmetụta hypoglycemic bụ nke sulfonamides na-eme ka ọ dịkwuo mma (gụnyere ndị na-ahụ maka hypoglycemic oral, sulfanilamides), MAO inhibitors (gụnyere furazolidone, procarbazine, selegiline), carbonic anhydrase inhibitors, ndị na-egbochi ACE, ndị na-egbochi NSAIDs (gụnyere salicylides), anabolic (gụnyere stanozolol, oxandrolone, methandrostenolone), androgens, bromocriptine, tetracyclines, clofibrate, ketoconazole, mebendazole, theophylline, cyclophosphamide, fenfluramine, njikere lithium, pyridoxine, quinidine, quinine, chlo, etin, chlo, etin, chlo.

Glucagon, somatropin, GCS, mgbochi mgbochi nke ọnụ, estrogens, thiazide na “loop” diuretics, ndị na-egbochi calcium, homonụ thyroid, heparin, sulfin pyrazone, sympathomimetics, danazole, tricyclic antidepressants, calcium chloride, moron, belata mmetụta hypogly. nicotine, phenytoin, epinephrine, histamine H1 na-egbochi ihe mgbochi.

Beta-blockers, reserpine, octreotide, pentamidine nwere ike ịkwalite ma belata mmetụta hypoglycemic nke insulin.

Azu ọgwụ ekwekọghị na ngwọta na ọgwụ ndị ọzọ.

Nhazi ọkwa nosological (ICD-10)

Protafan ® HM Penfill ®

Ọgwụ mlọ Ọgwụ

Mmetụta ahụ na-ebido n'ime elekere 1,5 mgbe sc nchịkwa, rute kacha elu mgbe elekere 4-12 wee dịgide ruo awa 24. A na-eji Protafan NM Penfill maka ọrịa shuga na-akpata insulin na-abụ insulin basal yana insulin na-eme obere ihe, maka insulin na-adabere , yana njikọ yana insulins na-eme ngwa ngwa.

Usoro onunu ogwu na nhazi

Protafan ® HM Penfill ®

P / c. Ezubere ọgwụ a maka nchịkwa okpuru ala. Enweghị ike ịbanye na insulin insulin.

A na-ahọrọ ọ̀gwụ nke ọgwụ n’otu n’otu, na-eburu n'uche mkpa ndị ọrịa. Dị ka ọ dị, chọrọ insulin dị n'etiti 0.3 na 1 IU / kg / ụbọchị. Ihe a chọrọ kwa ụbọchị maka insulin nwere ike ịdị elu karịa n’ebe ndị ọrịa na - eguzogide ọgwụ insulin (dịka ọmụmaatụ, n’oge uto, yana n’ebe ndị ọrịa na - ebu oke ibu), ma belata ndị ọrịa nwere ọgwụ insulin nke na - emepụtakarị.

Enwere ike iji Protafan ® NM na monotherapy yana yana insulin ngwa ngwa ma ọ bụ nke dị mkpụmkpụ.

A na-enyekarị Protafan ® NM subcutaneously na apata ụkwụ. Ọ bụrụ na nke a dabara adaba, mgbe ahụ injections nwekwara ike ime na ogiri mgbịrịsị ihu, na mpaghara gluteal ma ọ bụ mpaghara mpaghara akwara dị mma nke ubu. Site na iwebata ọgwụ n’apata apata, enwere mwepu nwayọ karịa mgbe etinyere n’akụkụ ndị ọzọ. Ọ bụrụ ntụtụ ka ejiri n'ogiri gbatịa anụ ahụ, belata ọghọm nchịkwa ọbara intramuscular nke ọgwụ na-ebelata.

Mkpịsị ahụ kwesịrị ịdị n’okpuru anụ ahụ ma ọ dịkarịa ala 6 sekọnd, nke na-ekwe nkwa ị aụ ọgwụ zuru oke. Okwesiri igbanwe ebe igba ogwu n’etiti mpaghara anatomical iji gbochie mmepe nke lipodystrophy.

Emebere Protafan ® NM Penfill ® maka iji insulin inspekt Novo Nordisk yana agịga NovoFine ® ma ọ bụ NovoTvist ®. Ekwesịrị ịchọpụta nkọwa zuru ezu maka ojiji na nchịkwa nke ọgwụ ahụ.

Ọrịa concoitant, nke na-efe efe ma na-efe efe, na -emekarị ahụ insulin nwere ahụ. Ọ ga-adị mkpa ịgbanwe nguhie ma ọ bụrụ na onye ọrịa ahụ nwere ọrịa ndị akụrụ, akụrụ, ọrụ akwara, pituitary ma ọ bụ thyroid gland. Mkpa maka ịhazigharị dose nwekwara ike ibilite mgbe ị na-agbanwe mmega ahụ ma ọ bụ nri onye ọrịa na-eri. Imezi dose mgbe ị na-ebufe onye ọrịa n’otu ụdị insulin na nke ọzọ

Dodoụbiga ya ókè

Ọrịa mmepe nke hypoglycemia (ọsụsọ oyi, palpitations, ịma jijiji, agụụ, oke iwe, mgbakasị ahụ, isi ọwụwa, ụkwara ume ọkụ, enweghị mmeghari, ikwu okwu na nkwarụ ọhụụ, ịda mba). Nnukwu hypoglycemia nwere ike ibute mmebi nke ọrụ ụbụrụ, coma, na ọnwụ ruo nwa oge ma ọ bụ nke na-adịgide adịgide.

Ọgwụgwọ: shuga ma ọ bụ ihe glucose dị n'ime (ọ bụrụ na onye ọrịa maara), s / c, i / m ma ọ bụ iv - glucagon ma ọ bụ iv - glucose.

Ọnụ ahịa ahịa ọgwụ na Moscow

Ihe omuma banyere onu ahia ogwu abughi onyinye iji ere ma obu izuta ngwa ahia.
Ezubere ozi a iji tulee ọnụahịa dị na ụlọ ahịa ọgwụ na-arụ ọrụ dị ka edemede nke 55 nke Iwu Iwu "N'elu Ngwọta Ọgwụ" nke ụbọchị 12.04.2010 N 61-ФЗ.

Mwepụta wepụtara ya na ihe mejupụtara

Mpempe usoro onunu ogwu - nkwusioru maka ochichi nke ochichi: di ocha, mgbe a na - aputa ihe n'ime mmiri na - acha odo odo na mmiri di ocha, a na - ejighachi ya iwe (10 ml na karama na enweghi iko, karama 1 n’ime kaadiboodu).

Ihe na - arụ ọrụ: insulin-isophan (inyocha mkpụrụ ndụ mmadụ), n'ime karama 1 - 100 mba dị iche iche, nke kwekọrọ na 3.5 mg nke insulin mmadụ na-eme ka mmiri na-eme ihe.

Ihe ndi ozo: protamine sulfate, phenol, metacresol, sodium hydrogen phosphate dihydrate, glycerol, zinc chloride, sodium hydroxide na / ma obu hydrochloric acid, mmiri injection.

Usoro onunu ogwu na nhazi

Ejiri protafan NM na-achịkwa subcutaneously.

A na-ahọrọ ọgwụ ahụ n'otu n'otu dabere na mkpa nke onye ọrịa, ọ na-abụkarị 0.3-1 IU / kg kwa ụbọchị. Mkpa nwere ike belata na ndị ọrịa nwere insulin resogenous mmepụta insulin ma ọ bụ karịa na ndị ọrịa nwere insulin na-eguzogide (dịka ọmụmaatụ, na oke ibu na oge ntozu).

Enwere ike iji Protafan NM mee ihe dịka otu ọgwụ yana yana insulin ngwa ngwa ma ọ bụ dị mkpụmkpụ.

N'ọnọdụ mgbe enwere ịchọrọ insulin ọgwụ ike, enwere ike iji mmachi ahụ mee ka insulin basal (injections na mgbede na / ma ọ bụ n'ụtụtụ) yana insulin dị mkpụmkpụ ma ọ bụ ngwa ngwa (a ga-ejikọ ọnụ ya na nri). Ọ bụrụ na ọ ga - ekwe omume ị nweta njikwa glycemic dị mma, mgbe ahụ, nsogbu ndị ọrịa shuga na - apụta mgbe e mesịrị, yabụ mmadụ kwesịrị ịgbalịsi ike ịkwalite njikwa metabolic, jiri nlezianya na-achịkwa ọkwa nke glucose n'ọbara.

A na-ejikarị Protafan HM eme ihe n'ụzọ dị n'okpuru mpaghara apata ụkwụ. Nwekwara ike banye na mgbidi akụkụ ihu, n'ime mpaghara adịghị ike nke ubu, ma ọ bụ banye mpaghara gluteal. Ka osila dị, na nke mbụ, amachibidoro ị drugụ ọgwụ ngwa ngwa.

Iji belata ihe ọghọm irighiri intramuscular mberede, ekwesịrị itinye ntụtụ n’oghere akpụkpọ ahụ ịgbatị. Iji gbochie mmepe nke lipodystrophy, a na-atụ aro ịgbanwe ebe ntụtụ n'ime mpaghara anatomical.

N'ime ndị ọrịa nwere nsogbu gbasara akụrụ na ịba ọcha n'anya, a na-ebelata mkpa insulin dị, yabụ, achọrọ ịgbatị dose nke Protafan NM.

Enwere ike ịnwe nnabata ahụ naanị sirinji insulin na ọnụ ọgụgụ na-enye gị ohere ịlele usoro achọrọ na nkeji nke arụmọrụ. Vials bụ maka naanị onwe gị.

Tupu iji Protafan NM:

• Lelee nkwakọ ngwaahịa ahụ wee gbaa mbọ chọọ ụdị insulin ziri ezi.
• Kwee ka ọgwụ ahụ kpoo okpomoku ka ọ dị naanị n ’ụlọ ahụ wee jikọta nkwụsị ahụ,
• Iji kpochapụ ihe eji egbochi roba.

Amachibidoro ọgwụ a iji mee ihe ndị a:

• Na nfuli insulin
• Ikpuchita nke karama a na-efu efu ma ọ bụ tọghe
• Edebere ọgwụ ahụ n'ụzọ na-ezighi ezi ma ọ bụ oyi kpọnwụrụ,
• Mgbe agwakọchara, ọgwụ anaghị akpọghachite (ọ naghị abụkarị urukpuru na ọcha).

Usoro injection mgbe ị na-eji Protafan NM:

• Ebido nkwusioru, iji mee nke a, tụgharịa kalama n'etiti nkwụ (na-ekwusi ya ike ma ọ bụrụ na ọ ga-eme ụlọ ahụ)
• Denye ikuku n'ime sirinji na ọnụego kwekọrọ na insulin chọrọ,
• Mee ka ikuku banye n’ime vial ahụ site n’ịkpọpu anụ ahụ a na-akpọ roba wee pịa maịpịa ihe.
• Tụgharị karama ahụ, nweta insulin nke ziri ezi,
• Wepu agịga na vial ma wepụ ikuku si sirinji,
• Lelee dose ziri ezi
• Gbanye ozugbo.

Usoro injection mgbe ị na-eji Protafan NM na insulin eme mkpụmkpụ:

• Bido nkwusioru ahụ (dị ka akọwara n’elu).
• Na-anakọta ikuku n'ime sirinji na olu kwekọrọ na ọnụọgụ nke Protafan NM, fanye ya na karama ahụ kwesịrị ekwesị ma wepụ agịga ahụ,
• Iji dọpụta ikuku n'ime sirinji na olu nke kwekọrọ na insulin nke na-adị mkpụmkpụ (ICD), banye n'ime karama ahụ kwesịrị ekwesị,
• Tụgharịa karama ahụ wee pịa ọgwụ ICD,
• Wepụ agịga, wepụ ikuku site na sirinji ma chọpụta izizi nke ọgwụ achọrọ,
• Tinye Protafan NM n'ime agịga ahụ n'ime karama ahụ, pịa karama ahụ kpoo ma pịa ọgwụ ịchọrọ,
• Wepu agịga na vial na ikuku si sirinji, lelee izizi nke ọgwụ a chịkọtara,
• Gbanye na ngwakọta insulin dị ogologo na-arụ ọrụ ma dị mkpụmkpụ.

Ekwesịrị ịnakọta insulin mgbe niile n'usoro a kọwara n'elu!

Iwu nke nchịkwa ọgwụ:

• Jiri mkpịsị aka abụọ, kechie akpụkpọ ahụ n’ogige atụrụ, fanye agịga n’ime ya n’akụkụ dị ihe dịka 45 Celsius ma gbanye insulin n’ahụ.
• Hapụ agịga ahụ n’akpụkpọ anụ ahụ ma ọ dịkarịa ala 6 sekọnd iji hụ na enyere gị ọgwụ ahụ nke ọma.

Nsonaazụ

Mmetụta dị n'akụkụ n'oge ọgwụgwọ Protafan NM na-abụkarị ọgwụ na-adabere ma na-esite na ọgwụ insulin. Mmeghachi mmetụta a na-ahụkarị bụ hypoglycemia, nke na-etolite mgbe enwere oke ịba ụba nke insulin n'ihe metụtara mkpa ọ dị. Ọrịa hypoglycemia siri ike nwere ike ibute nsụhọ na / ma ọ bụ ihe ọdịdọ, na-eduga n'ịrụ ọrụ ụbụrụ na ọbụna ọnwụ.

Effects nwere ike inwe mmetụta ọjọọ:

Site n'akụkụ nke sistem: dịghị mgbe (> 1/1000, 5 11111 Rating: 5 - 1 votu

Ime na lactation

Enweghị mgbochi ọ bụla na ojiji nke insulin n'oge ime, ebe insulin anaghị agafe ihe mgbochi placental.

Ma ọrịa hypoglycemia na hyperglycemia, nke nwere ike ịmalite n'ọnọdụ nke usoro ọgwụgwọ ahọpụtaghị nke ọma, na-eme ka ihe ọghọm ndị dị na nwa ebu n'afọ na ọnwụ nke nwa ebu n'afọ. Shouldmụ nwanyị dị ime nwere ọrịa shuga kwesịrị ileba anya n’oge ha dị ime, ha kwesiri ijikwa ikike ịchịkọta glucose ọbara, otu ndụmọdụ a na-emetụta ụmụ nwanyị na-eme atụmatụ ime.

Mkpa insulin na-agbadata n'oge ọnwa atọ nke mbụ nke afọ ime wee jiri nwayọ na nke abụọ na nke atọ.

Mgbe ịmụchara nwa, mkpa insulin dị, dịka iwu, na-alaghachi ọsọ ọsọ na ọkwa a hụrụ tupu ime ime.

Enweghịkwa mmachi iji ọgwụ Protafan® NM eme ihe n’oge a na-enye nwa ara. Conmụrụ ụmụ nwanyị ọgwụ insulin n'oge a na-enye nwa adịghị ize ndụ nye nwa ahụ. Agbanyeghị, ọ nwere ike ịdị mkpa idozigharị usoro usoro ọgwụ Protafan® NM na / ma ọ bụ nri.

Mmekọrịta na ọgwụ ndị ọzọ

E nwere ọtụtụ ọgwụ na-emetụta mkpa maka insulin.

Hypoglycemic mmetụta nke insulin welie onu hypoglycemic mmadụ, monoamine oxidase inhibitors, angiotensin n'ịtụgharị enzyme inhibitors, carbonic anhydrase inhibitors, nhọrọ beta-blockers, bromocriptine, sulfonamides, anabolic Steroid, tetracyclines, clofibrate, ketoconazole, mebendazole, pyridoxine, theophylline, cyclophosphamide, fenfluramine, ọgwụ ọjọọ lithium salicylates .

Mmetụta hypoglycemic nke insulin na-ebelata site na mgbochi mgbochi nke ọnụ, glucocorticosteroids, homonụ thyroid, thiazide diuretics, heparin, tricyclic antidepressants, sympathomimetics, hormone hormone (somatropin), danazol, clonidine, ngwa ngwa calcium channel blozox, diafenin, diafenin.

Ndị na - egbochi Beta na - egbochi ọrịa hypoglycemia ma belata mgbake mgbe hypoglycemia gasịrị.

Octreotide / lanreotide nwere ike ịbawanye ma wedata mkpa ahụ insulin nwere.

Mmanya na-egbu egbu nwere ike iwelie ma ọ bụ ibelata mmetụta hypoglycemic nke insulin. Ndakọrịta

Ekwesighi itinye mgbakwunye insulin na ngwakọta infusion.

Njirimara ngwa

Ọgwụ ezughị ezu ma ọ bụ ịkwụsị ọgwụgwọ, karịsịa na ụdị ọrịa shuga 1, nwere ike iduga mmepe nke hyperglycemia.

Dịka iwu, mgbaàmà mbụ nke hyperglycemia pụtara nke nta nke nta, ọtụtụ awa ma ọ bụ ụbọchị. Ihe mgbaàmà nke hyperglycemia gụnyere akpịrị ịkpọ nkụ, mmamịrị na-abawanye, ọgbụgbọ, ọgbụgbọ, ura, akpịrị na akpọnwụ akpịrị, akpịrị kpọrọ nkụ, agụụ, na ọdịdị nke acetone ísì ikuku. Enweghị ọgwụgwọ kwesịrị ekwesị, hyperglycemia na ndị ọrịa nwere ọrịa shuga 1 nwere ike ibute ketoacidosis mamịrị, ọrịa na-egbu egbu.

Hypoglycemia nwere ike itolite ma ọ bụrụ na enyere insulin nnukwu ọgwụ n'ihe metụtara mkpa onye ọrịa.

Izere nri ma ọ bụ imega ahụ siri ike na-enweghị nhazi nwere ike iduga hypoglycemia.

Mgbe ha kwusịrị metabolism metabolism, dịka ọmụmaatụ, n'oge ọgwụgwọ insulin ike, ọrịa nke ndị ọrịa na-ahụ maka ha nwere ike gbanwee - ihe ga - ebute hypoglycemia, nke a ga - agwa ndị ọrịa. Ihe mgbaàmà ịdọ aka na ntị na-adịkarị nwere ike ịnwe ọrịa shuga ogologo oge.

Inyefe ndị ọrịa na ụdị insulin ọzọ ma ọ bụ insulin nke onye nrụpụta ọzọ ga-ebufere naanị nlekọta ahụike. Ọ bụrụ n’ịgbanwe itinye uche, onye na-emeputa, ụdị, ụdị (insulin mmadụ, analog nke insulin) na / ma ọ bụ usoro eji emepụta, ịnwere ike igbanwe insulin. Ndị ọrịa na-eme ọgwụgwọ na Protafan® NM nwere ike ịchọ mgbanwe mgbanwe ma ọ bụ mmụba ugboro ole nke injelo dị ka iji ya na ọgwụ insulin na-emebu. Ọ bụrụ nhazigharị ọgwụ dị mkpa mgbe ị na-ebufe ndị ọrịa ọgwụgwọ na Protafan® NM, enwere ike ịme nke a tupu iwebata ọgwụ mbụ ma ọ bụ izu mbụ ma ọ bụ ọnwa ọgwụgwọ.

Dịka ọ dị na usoro insulin ndị ọzọ, mmeghachi omume nwere ike ịmalite na ebe ntụtụ, nke ihe mgbu na-egosipụta, mgbu na-acha ọbara ọbara, hives, mbufụt, hematoma, ọzịza na itching. Changinggbanwe saịtị ntụtụ mgbe niile na mpaghara otu ahụ ga - enyere aka belata mgbaàmà ma ọ bụ gbochie mmepe nke mmeghachi omume ndị a. Mmeghachi omume na-apụkarị n'ime ụbọchị ole na ole ruo ọtụtụ izu. N'ọnọdụ ndị na-adịghị ahụkebe, ịkwụsị Protafan® NM nwere ike ịdị mkpa n'ihi mmeghachi omume na saịtị ịgba ahụ.

Tupu njem njem oge ọ ga-eme njem, onye ọrịa ahụ kwesịrị ịgakwuru dọkịta ya, ebe mgbanwe mpaghara oge pụtara na onye ọrịa ga-eri ma nyekwa ya insulin n'oge dị iche. Enweghị ike iji insulin insulin rụọ ọrụ na nfuli insulin.

Ojiji nke otu ọgwụ thiazolidinedione na nhazi insulin

A kọwo ọrịa banyere mmepe nke obi nkụda mmụọ na ọgwụgwọ nke ndị ọrịa nwere thiazolidinediones yana njikọ insulin, ọkachasị ma ọ bụrụ na ndị ọrịa dị otú ahụ nwere ihe ọghọm maka mmepe nke ọrịa obi na-adịghị ala ala. Ekwesiri iburu n'uche eziokwu a mgbe ị na-edepụta ọgwụ njikọta na thiazolidinediones na nkwadebe insulin na ndị ọrịa. Mgbe ị na-edepụta usoro ọgwụgwọ dị otú a, ọ dị mkpa iji nyochaa nyocha ahụike nke ndị ọrịa iji chọpụta akara na akara nke obi na-adịghị ala ala, oke ibu na ọnụnọ edema. Ọ bụrụ na mgbaàmà nke nkụda obi na-akawanye njọ n'ime ndị ọrịa, a ga-akwụsị ịgwọ ya na thiazolidinediones.

Mmetụta ikike ịkwọ ụgbọ ala ma jiri usoro rụọ ọrụ

Ike nke ndị ọrịa itinye uche na ọnụego mmeghachi omume nwere ike ọfụma n'oge hypoglycemia, nke nwere ike ịdị ize ndụ n'ọnọdụ ebe ikike ndị a dị ezigbo mkpa (dịka ọmụmaatụ, mgbe ha na-anya ụgbọala ma ọ bụ jiri igwe na arụ ọrụ). A dụrụ ndị ọrịa ọdụ ka ha mee ihe iji gbochie mmepe nke hypoglycemia mgbe ha na-anya ụgbọala. Nke a dị ezigbo mkpa maka ndị ọrịa na-enweghị ma ọ bụ belata ihe mgbaàmà nke ihe ndị na - ebilite hypoglycemia ma ọ bụ na - ata ahụhụ site na ọrịa hypoglycemia ugboro ugboro. N'ụdị ndị a, ekwesịrị ịtụle maka ịkwọ ụgbọala na ịrụ ụdị ọrụ ahụ.

Ọnọdụ nchekwa

Chekwaa n 'okpomoku okpukpu 2 Celsius rue 8 Celsius (na friji), ma obughi nso friza. Emela ifriizi.

Debe karama ahụ n’ime igbe kaadi iji chebe onwe ya pụọ ​​n’ọkụ.

Maka karama mepere emepe: echekwala na friji. Na-echekwa na okpomọkụ agaghị agafe 25 Celsius C maka izu isii.

Ekwesịrị ichebe Protafan® NM site na oke ọkụ na ọkụ. Ekwela ka ụmụaka ghara iru ya.