Insulin Protafan: ntuziaka, analogues, nyocha

• Mlọ ọgwụ
• Ihe ngosi maka ojiji
• Ofzọ nke ngwa
• Nsonaazụ
• Ihe ngbanwe
• Ime
• Mmekọrịta na ọgwụ ndị ọzọ
• Dodoụbiga ya ókè
• Ọnọdụ nchekwa
• Mpempe mwepụta
• Ngwakọta
• Nhọrọ

Protafan NM - ogwu antidiabetic.
Mmetụta dị ala nke insulin na-eme bụ ịkwalite mbido nke glucose site na anụ ahụ mgbe ọ jikọsịrị insulin na ndị na-anabata uru ahụ na mkpụrụ ndụ, yana mgbochi nke mwepụta nke glucose site na imeju.
Na nkezi, profaịlụ nke usoro mgbe usoro ọgwụ Subcutaneous dị ka ndị a: mmalite nke ime ihe dị n'ime awa 1.5, oke kachasị na-anọ bụ site na 4 ruo 12:00, oge nke ime ihe dị ka awa 24.

Mlọ ọgwụ

Ọkara ndụ nke insulin n'ọbara bụ ọtụtụ nkeji, ya mere, profaịlụ nke ihe ndị a na - akwadebe insulin bụ naanị site na njimara mmado. Usoro a dabere n'ọtụtụ ihe (dịka ọmụmaatụ, na onodu insulin, usoro na ebe ịgba ọgwụ, ọkpụrụkpụ nke anụ ahụ dị n'okpuru ala, ụdị ọrịa shuga), nke na-ekpebi nnukwu mgbanwe nke nsonaazụ insulin na otu na ndị ọrịa dị iche iche.
Ibepu ulo Nta kachasị na plasma ruru n'ime awa 2-18 ka nchịkwa ọgwụ gachara.
Nkesa. Nnukwu nnabata nke insulin na protein ndị na-enye plasma, ewezuga ịmịnye ọgwụ mgbochi nje na ya (ọ bụrụ na ọ dị), achọpụtaghị.
Metabolism. A na-ehichapụ insulin mmadụ site na insulin na-edozi ma ọ bụ enzymesgradable nke a pụrụ ịgbanwe agbanwe, ikekwe, site na protein disulfide isomerase. Achọpụtala saịtị dị iche iche ebe nkwụsịtụ (hydrolysis) nke irighiri insulin mmadụ. Ọ dịghị onye n'ime metabolites guzobere mgbe hydrolysis nwere ọrụ ndu.
Ojiji. Ogologo oge ndụ insulin nke ọkara ikpeazụ na-ekpebi site na nha nke iwere ya na anụ ahụ dị n'okpuru ala. Ọ bụ ya mere oge ndụ ọkara ndụ ikpeazụ (t½) ji egosi ọnụego nnabata, ọ bụghị iwepụ insulin site na plasma ọbara (t½ nke insulin si n'ọbara ọbara bụ naanị nkeji ole na ole). Dabere na nyocha, t½ bụ awa 5-10.

Ofzọ nke ngwa

Protafan NM bụ ịkwado insulin na-arụ ọrụ ogologo oge, yabụ enwere ike iji ya naanị ma ọ bụ yana yana insulin.
Usoro onunu ogwu nke insulin bu ndi mmadu n’onwe ya wee kpebie ya dika odi ya nma.
Ihe a chọrọ kwa ụbọchị maka insulin na-abụkarị site na 0.3 ruo 1.0 IU / kg / ụbọchị. Ihe a chọrọ kwa ụbọchị maka insulin nwere ike ịbawanye na ndị ọrịa na-eguzogide ọgwụ insulin (dịka ọmụmaatụ, n'oge uto ma ọ bụ buru oke ibu) na ibelata ndị ọrịa nwere ihe insulin endogenous Production.
Dose ukpụhọde
Ọrịa concoitant, ọkachasị ọrịa na ahụ ọkụ, na-ebulitekarị mkpa onye ọrịa nwere insulin. Akụrụ na-agakọ, imeju, ma ọ bụ adrenal, pituitary, ma ọ bụ ọrịa thyroid chọrọ mgbanwe nke dose.
Ọ nwekwara ike ịdị mkpa iji dozigharị azụ ma ọ bụrụ na ndị ọrịa agbanwee mmega ahụ ha ma ọ bụ usoro nri ha. Enwere ike ịhọrọ ntụgharị mgbe ị na-ebufe ndị ọrịa na usoro insulin ndị ọzọ.
Okwu mmeghe
Protafan NM ezubere maka ntụtụ subcutaneous naanị. A naghị emechi insulin insulin.
A na-enyekarị Protafan HM n'okpuru anụ dị n'apata ụkwụ. Nwekwara ike banye mpaghara nke mgbidi akụkụ ihu, mgbaka ma ọ bụ akwara nwere ike iche.
Site na iji irighiri okwu dị n'okpuru apata ụkwụ, nnabata insulin dị nwayọ karịa mgbe etinyere n’akụkụ ndị ọzọ nke ahụ.
Iwebata akpụkpọ atụrụ a dọtara adọka belata ohere ịbanye n’arụ ahụ.
Mgbe ịgba ntụtụ ahụ, agịga kwesịrị ịdị n’okpuru anụ ahụ ma ọ dịkarịa ala 6 sekọnd. Nke a ga - hụ na iwebata ọgwụ zuru oke.
Iji belata ihe dị na lipodystrophy, ekwesịrị ịgbanwe saịtị injection ọbụlagodi n'otu akụkụ ahụ.
Protafan NM n'ime vials eji sirinji insulin pụrụ iche, nke nwere agụmakwụkwọ kwesịrị ekwesị. Protafan HM na-abịa na ntuziaka ngwugwu nwere ozi zuru ezu maka iji.
Ntụziaka maka iji ọgwụ Protafan NM maka onye ọrịa
Ejila Protafan NM:
- na infusion nfuli,
- ma ọ bụrụ na ị na - eme ọgwụ insulin (na - egbochi ihe) na insulin mmadụ ma ọ bụ ihe ọ bụla ọzọ nke ọgwụ
- ma ọ bụrụ na ị na-eche na ị na-etolite hypoglycemia (shuga dị ala)
- ọ bụrụ na okpu plastik nchekwa adịghị adọkaghị oyi ma ọ bụ na-efu efu
(Karama ọ bụla nwere okpu plastik na-echebe ya iji gosi na ọ ga-emepe, ọ bụrụ na nnata karama ahụ, okpu ahụ anaghị adaba na snugly ma ọ bụ na-efu efu, a ga-akpọghachi karama ahụ n'ụlọ ahịa ọgwụ)
- Ọ bụrụ na echekwara ọgwụ ahụ n’ụzọ na-adịghị mma ma ọ bụ kpọnwụrụ akpọnwụ,
- ọ bụrụ na nkwusioru nke insulin na-acha ọcha na urukpuru n'otu mgbe agwakọchara.
Tupu ị theụ ọgwụ Protafan NM:
- lelee labeelu iji jide n'aka na ụdị insulin ka enyere dị,
- wepu okpu mkpuchi nchekwa ahi.
Otu esi eji nkwadebe insulin a
Protafan NM a na-ahụ maka ntinye n'okpuru anụahụ (subcutaneously). Ewekwala insulin ozugbo na akwara ma ọ bụ akwara. Gbanwee oge a na - agba ya mmiri ọ bụla, ọbụlagodi n'otu mpaghara ahụ iji belata ihe ize ndụ nke ịmeghe akara ma ọ bụ akara aka na anụ ahụ. Ebe kachasị mma maka ịgba onwe gị bụ ikpere, n'ihu apata ụkwụ ma ọ bụ ubu.
Ntinye Protafan NMọ bụrụ na a na-elekọta ya naanị ma ọ bụ mgbe ejiri ya insulin na-eme obere ihe
- Gbalịsie ike na ị na-eji sirinji insulin nke nwere agụmakwụkwọ kwesịrị ekwesị.
- Domo n'ime sirinji olu nke ikuku nke kwesiri ka insulin chọrọ gị wee banye n'ime vial ahụ.
- Soro ntuziaka dọkịta gị ma ọ bụ nọọsụ nyere gbasara usoro eji eji ọgwụ a.
- Ngwa ngwa tupu iji ya, tụgharịa otu karama nke Protafan ® NM n'etiti ọbụ aka gị ruo mgbe mmiri mmiri ahụ na-acha ọcha ma dịkwa nro. Ọkpali akpọnwụ kachasị mma mgbe a na-eme ka insulin na-ekpo ọkụ ka okpomoku dị n'ime ụlọ.
- Nye ọgwụ insulin n'okpuru ya. Jiri usoro ịgba ogwu nke dọkịta gị ma ọ bụ nọọsụ tụrụ aro ya.
- Jide agịga n'okpuru anụ ahụ ọ dịkarịa ala 6 sekọnd iji jide n'aka na a na-enye ọgwụ zuru ezu.
Childrenmụaka. Usoro insulin nke biosynthetic mmadụ dị mma ma dị mma n'ịgwọ ọrịa shuga n'ọgbọ dị iche iche ụmụaka na ndị nọ n'afọ iri na ụma. Mkpa insulin kwa ụbọchị na ụmụaka na ndị nọ n’oge uto na-adabere n’usoro ọrịa ahụ, ibu ahụ, afọ, nri, mmega ahụ, ogo nguzogide insulin na ogo nke mgbatị afọ.

Pharmacodynamics na pharmacokinetics

O kwesiri iburu n'uche na Protafan NM bu insulin onye nwere mmetụta ogologo oge, nke usoro ihe omimi nke ihe omimi nke DNA na-eji ọgịga arụpụta Saccharomyces cerevisiae. Ọgwụ a na-emekọrịta otu ihe nnabata nke dị na mpụga akwara sel cytoplasmic yana ị mepụta insulin-receptor complex. N'okwu a, mkpali nke usoro intracellular, dịka ọmụmaatụ, njikọ nke ihe dị mkpa enzymes: pyruvate kinase, hexokinase, glycogen synthetase na ndị ọzọ.

Glucose na ihe mejupụtara ọbara na-abawanye n'ihi njem ụgbọ mmiri intracellular ya, nke na-eme ka anụ ahụ dịkwuo elu, yana ịmịpụta lipogenesis na glycogenogenesis, na-ebelata ogo nke ịmịnye umeji nke imeju, na ndị ọzọ.

N'okwu a, a na-etinye insulin protafan na ọnụego dabere na ihe ndị dị ka usoro ịsụ ọgwụ, usoro, ụzọ nchịkwa na ụdị ọrịa shuga. Maka nke a, profaịlụ nke ike insulin nwere ike gbanwe.

Ọgwụ na-amalite ime n'ime awa 1-1.5 site na oge nchịkwa, a na-enweta nsonaazụ kachasị mgbe awa 4-12 gachara ma dịkarịa ala awa 24.

Mkpochapu na oke ọgwụ a bara uru na-adabere ebe na usoro nchịkwa, yana usoro onunu ogwu na itinye uche nke isi ihe dị na ọgwụ ahụ. Maximumnweta ọdịnaya insulin kachasị ọbara plasma na - apụta mgbe awa 2-18 dị n'okpuru n'ihi nchịkwa subcutaneous.

Ọgwụ a abanyeghị ná mmekọrịta a na-ahụ anya na protein protein, na-achọpụta naanị ọgwụ nje na-ebunye insulin. Na metabolism ọtụtụ insulin nọ n'ọrụ na-akpụpụta site na insulin mmadụ metabolitesị ga-eme ka ahụ dị gị mma.

Nsonaazụ

N'oge ọgwụgwọ a ọgwụ, dị ka njikọta nke Protafan -Penfill, mmetụta na-adịghị mma nwere ike ịmalite, ogo nke dabere na usoro onunu ogwu yana ọgwụ insulin.

Karịsịa, dị ka mmetụta dị n'akụkụ, hypoglycemia na-apụta. Ihe kpatara ekpughere ya dabere na oke nnweta insulin na mkpa ọ dị. N'otu oge, ọ fọrọ nke nta ka ọ bụrụ ihe na-agaghị ekwe omume ịchọpụta ugboro ole ọ na-adị.

Ọrịa hypoglycemia siri ike nwere ike ibute nsụhọ, ọnọdụ amamịghe, nsụhọ nwa oge ma ọ bụ nke na-adịgide adịgide nke ọrụ ụbụrụ, na nsonaazụ na-egbu egbu.

Na mgbakwunye, mmetụta ndị enwere ike ịmetụta ọrụ nke dịghịzi, ụjọ na usoro ndị ọzọ.

Ọ na-adịghị ekwe mmepe nke mmeghachi omume anaphylactic, akara nke juputara hypersensitivity, nsogbu na ọrụ nke digestive tract, angioedema,mkpụkpu umeobi dara ada, iweda ala ọbara mgbali na ndị ọzọ.

Protafan, ntuziaka maka ojiji (Usoro na usoro onunu ogwu)

Ejiri ọgwụ a na subcutaneously. N'otu oge ahụ, a na-ahọrọ usoro ọgwụgwọ ya n'otu n'otu, na-eburu n'uche mkpa onye ọrịa dị. Nke bụ eziokwu bụ na ndị ọrịa na - eguzogide ọgwụ insulin nwere mkpa dị elu.

Ọ bụkwa dọkịta na-ekpebi ọnụọgụ nke injections kwa ụbọchị na otu esi eji ọgwụ ahụ eme ihe n'ụdị ọgwụgwọ mono ma ọ bụ nkwonkwo, dịka ọmụmaatụ, na insulin, nke nwere ọrụ ngwa ngwa ma ọ bụ obere. Ọ bụrụ na ọ dị mkpa, a na-eme insulin kpụ ọkụ n'ọnụ site na iji nkwusioru a dị ka insulin basal yana njikọ insulin ngwa ngwa ma ọ bụ mkpụmkpụ. A na-enyekarị mmiri ọgwụ mgbochi dabere na nri.

Imirikiti ndị ọrịa na-eduzi Protafan NM subcutaneously taara na apata ụkwụ. A na-ahapụ ọgwụ mgbochi n'ime mgbidi abdominal, mana ihe mgbochi na ebe ndị ọzọ. Ihe mere bu na mgbe ogwu a ghabara n’ime apata ukwu ya, o na adota nwayukwu. A na-atụ aro ya ka igbanwe ebe ntụtụ iji gbochie mmepe lipodystrophy.

Usoro onunu ogwu na uzo ochichi

Protafan bụ ọgwụ na-eme obere ihe, yabụ enwere ike iji ya iche iche yana yana ọgwụ ndị na-eme obere oge, dịka ọmụmaatụ, Actrapid. A na-ahọrọ usoro onunu ogwu n’otu n’otu. Ihe a chọrọ kwa ụbọchị maka insulin dị iche maka ndị ọrịa mamịrị niile. Dị ka ọ na-adịkarị, o kwesịrị ịdị site na 0.3 ruo 1.0 IU kwa kilogram kwa ụbọchị. Site na oke ibu ma ọ bụ oge uto, iguzogide insulin nwere ike ịmalite, yabụ ihe a chọrọ kwa ụbọchị ga-abawanye. Site na mgbanwe mgbanwe na ndụ, ọrịa nke thyroid gland, pituitary gland, imeju na akụrụ, a na-edozi ọ̀tụ̀tụ̀ Protafan NM n'otu n'otu.

Ngwongwo ogwu

Mmetụta hypoglycemic na-apụta mgbe nkwarụ insulin na nkekọ ya na ndị na-anabata akwara na abụba. Njirimara:

• lowers glucose ọbara
• na - eme ka glucose na - emeziwanye sel,
• na-emezi lipogenesis,
• Na-egbochi iwepu glucose na umeji.

Mgbe nchịkwa subcutaneous gasịrị, a na-ahụ ọkwa kachasị nke protafan insulin n'ime awa 2-18. Mmalite nke ọrụ bụ mgbe awa 1.5 gachara, nsonaazụ kachasị na-apụta mgbe elekere 4-12 gachara, oge ngụkọta bụ awa 24. N'ime ọmụmụ ụlọ ọgwụ, ọ gaghị ekwe omume ịchọpụta ọrịa carcinogenicity, genotoxicity na mmetụta ọjọọ na ọrụ omumu, ya mere a na-ewere Protafan dị ka ọgwụ dị mma.

Analogs nke Protafan

Aha	Emeputa
Insuman Bazal	Sanofi-Aventis Deutschland GmbH, Germany
Br-Insulmidi ChSP	Bryntsalov-A, Russia
Humulin NPH	Eli Lilly, United States
Actrafan HM	Novo Nordisk A / O, Denmark
Berlinsulin N Basal U-40 na Berlisulin N Basal Pen	Berlin-Chemie AG, Germany
Humodar B	Indar Insulin CJSC, Ukraine
Biogulin NPH	Bioroba SA, Brazil
Homofan	Pliva, Croatia
Isofan Insulin anwụ Monde	AI CN Galenika, Yugoslavia

N'okpuru ebe a, vidiyo na-ekwu maka ọgwụ ọgwụ isofan na-akpata:

Ọ ga-amasị m ịme ndozi nke m na vidiyo ahụ - a machibidoro iwu ịhazi insulin ogologo oge!

Mmekọrịta na ọgwụ ndị ọzọ

Ọgwụ ndị na-ebelata mkpa insulin:

• Ihe mgbochi ACE (captopril),
• ọgwụ hypoglycemic nke ọgwụ,
• MAO monoamine oxidase inhibitors (furazolidone),
• salicylates na sulfonamides,
• ndị na - achọghị beta-blockers (metoprolol),
• anabolic steroid

Ọgwụ na-abawanye mkpa insulin:

• glucocorticoids (prednisone),
• nnabata ọmiko
• ogwu gboro ya
• morphine, glucagon,
• Ndị na-emegide nnu
• thiazides,
• homonụ thyroid.

Etu esi echekwa insulin?

Ntụziaka ahụ kwuru na ịnweghị ike ịhapụ ọgwụ ahụ. Chekwaa n’ebe di nro n’ebe okpomoku di 2 ruo 8. Ekwesịrị ịchekwa karama ma ọ bụ katrijị emeghe na friji n'ime ebe gbara ọchịchịrị ruo izu isii ruo mgbe okpomọkụ dị ogo 30.

Isi ọghọm nke Protafan na analorọ ya bụ ọnụnọ nke oke arụ ọrụ awa isii na isii ka nchịkwa gasịrị. N'ihi nke a, onye ọrịa mamịrị ga-ebu ụzọ kpaa nri ya tupu oge eruo. Ọ bụrụ n’erighị n'oge oge a, hypoglycemia na-amalite. Ndị inyom dị ime na ụmụaka nwere ike iji ya.

Sayensị guzosighị ike, enwere insulins ndị kachasị ọhụrụ Lantus, Tujeo na ndị ọzọ. Ya mere, n'ọdịniihu, a ga-atụgharị onye ọ bụla ọgwụ ọhụrụ iji belata ihe ize ndụ hypoglycemia.

Dodoụbiga ya ókè

N'ọnọdụ ụfọdụ, ịdoụ ọgwụ insulin na-eduga na mmepe nke hypoglycemia, nke nwere ike ịbụ nnukwu nsogbu dịgasị iche. Mgbe enwere hypoglycemia dị nwayọọ, onye ọrịa ahụ nwere ike iwepu ya n'adabereghị na ya site na itinye ngwaahịa dị ụtọ. Ya mere, ọtụtụ ndị na-arịa ọrịa shuga na-eburu ha ihe ọetsụ variousụ dị iche iche: ụtọ, kuki na ihe ndị ọzọ.

Ọnọdụ siri ike nwere ike ibute enweghị mmụọ. N'okwu a, a na-eme ọgwụgwọ pụrụ iche site na ntinye nke usoro 40% dị egwu Dextrose ma obu Glucagon - intramuscularly, subcutaneously. Ma mgbe ọ nwetasịrị onwe ya, onye ọrịa ahụ kwesịrị iri nri nwere carbohydrate ozugbo iji gbochie ịmaliteghachi hypoglycemia na ọrịa ndị ọzọ na-achọghị.

Ntụziaka dị mkpirikpi

A na-emepụta Protafan n'ụzọ ndụ. A na-ewebata DNA dị mkpa maka njikọ insulin n'ime microorganisms nke yist, emesịa ha malitere imepụta proinsulin. Insulin enwetara mgbe ọgwụgwọ enzymatic gasịrị bụ mmadụ. Iji mee ka ihe omume ya dịkwuo ogologo, a na-agwakọta homonụ ahụ na protamine, a na-akụkwa ya site na iji teknụzụ pụrụ iche. A na-eji ọgwụ mepụtara n'ụzọ dị otú a site na ihe mejupụtara mgbe niile, ị nwere ike ijide n'aka na ngbanwe nke karama ahụ agaghị emetụta shuga ọbara. Maka ndị ọrịa, nke a bụ ihe dị mkpa: ihe ole na ole na-emetụta ọrụ insulin, ụgwọ dị mma maka ọrịa shuga ga-abụ.

Protafan HM dị na iko vials nwere usoro 10 ml. N’ụdị a, ọgwụ ndị ụlọ ọgwụ na ndị ọrịa shuga na-anara insulin. N'ime igbe kaadiboodu 1 kalama na ntuziaka maka ojiji.

Protafan NM Penfill - ndị a bụ katridges 3 ml nke enwere ike idobe na pensọ NovoPen 4 (usoro 1) ma ọ bụ NovoPen Echo (nkeji 0,5). Maka ịdị mma nke ịgwakọta na katalọgụ ọ bụla iko bọọlụ. Ihe ngwugwu ahụ nwere katọnges na ntuziaka 5.

Mbelata shuga ọbara site na ibuga ya na nsị anụ ahụ, na-eme ka njikọ glycogen nwee akwara na umeji. Ọ na - akpali nguzobe nke protein na abụba, yabụ, na - enye aka n'ịba ụba.

A na-eji ya iji mee ka shuga na-ebu ọnụ nkịtị: n'abalị na n'etiti nri. Enweghi ike iji protafan mezie glycemia, a na-ezube insulins dị mkpa maka ebumnuche ndị a.

Mkpa insulin na-abawanye na nrụgide akwara, mmerụ ahụ na nke uche, mbufụt, na ọrịa na-efe efe. Of ofụ mmanya na-egbu egbu n'ime ọrịa shuga abụghị ihe a na-achọghị, n'ihi na ọ na-eme ka uru nke ọrịa ahụ dịkwuo elu ma nwee ike ịkpasu hypoglycemia siri ike.

Imeghari dose mgbe ị na-a certainụ ọgwụ ụfọdụ. Mụbaa - site na iji ọgwụ mgbarụ na ọgwụ ọgwụ homonụ. Mbelata - n'ihe banyere otu oge nchịkwa na mbadamba shuga dị ala, tetracycline, aspirin, ọgwụ antihypertensive site na otu nke ndị na - anabata ndị na - anabata ụdọ AT1 na ndị na - egbochi ACE.

Mmetụta dị njọ nke insulin ọ bụla bụ hypoglycemia. Mgbe ị na-eji ọgwụ ọgwụ NPH, ihe ize ndụ nke ịda shuga n'abalị bụ nke kachasị elu, ebe ọ bụ na ha nwere oke ọrụ. Nocturnal hypoglycemia kacha dị ize ndụ na ọrịa shuga mellitus, ebe onye ọrịa ahụ enweghị ike ịchọpụta ma kpochapụ ya n'onwe ha. Obere shuga n’abali bụ nsonaazụ nke ahọpụtara nke ọma ma ọ bụ njirimara metabolic nke mmadụ.

N'ihe na-erughị 1% nke ndị ọrịa mamịrị, insta protafan na-akpata mmeghachi omume nfụkasị mpaghara dị nro n'ụdị ọnya, itching, ọria na ebe injection. Ihe puru iche nke nnukwu ahu anataghi emeputara na erughi 0.01%. Mgbanwe na abụba subcutaneous, lipodystrophy, nwekwara ike ịdaba. Ihe ize ndụ ha dị elu ma ọ bụrụ na esoghị usoro ịgba ntụtụ ahụ.

Amachibidoro Protafan iji ndị ọrịa nwere ọrịa akpịrị ma ọ bụ ede ede Quincke maka insulin. Dịka dochie anya, ọ ka mma iji ọ bụghị insulin nke NPH nwere ihe mejupụtara ya, kama insulin analogues - Lantus ma ọ bụ Levemir.

Ndị ọrịa mamịrị ekwesịghị iji Protafan mee ihe n'ịrụ ọrụ hypoglycemia, ma ọ bụ ọ bụrụ na-ehichapụ ihe mgbaàmà ya. Achọpụtara na insulin analogues na nke a dị nchebe karịa.

Nkọwa	Protafan, dị ka ihe NPH niile, na-ekpughere ya na vial. N'okpuru ebe enwere ntụpọ ọcha, n’elu - mmiri mmiri translucent. Mgbe agwakọta, ngwakọta ahụ dum na-acha ọcha. Ta ụta nke ihe arụ ọrụ bụ 100 nkeji kwa mililita.
Dị Mwepụta
Ngwakọta	Ngwakọta ọrụ na-arụ ọrụ bụ insulin-isophan, ihe inyeaka: mmiri, sọlfọ protamine iji mee ka ogologo oge nke ihe, phenol, metacresol na zinc ion dị ka ihe nchekwa, ihe iji dozie acidity nke ihe ngwọta.
Ihe omume
Ihe na-egosi	Ọrịa shuga dị n'ime ndị ọrịa chọrọ ọgwụ insulin, n'agbanyeghị afọ ole ọ dị. Site na oria 1 - site na mmalite nke nsogbu nke carbohydrate, ya na ụdị nke 2 - mgbe ọgwụ ịbelata shuga na nri adịghị arụ ọrụ nke ọma, na hemoglobin glycated karịrị 9%. Afọ ime na ụmụ nwanyị dị ime.
Nhọrọ onunu ogwu	Ntụziaka ahụ enweghị ọgwụ a tụrụ aro ya, ebe ego insulin chọrọ maka ndị ọrịa mamịrị dị iche. A na-agbakọ ya na ndabere nke data glycemia na-ebu ọnụ. A họọrọ usoro insulin maka nchịkwa ụtụtụ na nke mgbede - ngụkọta oge nke insulin maka ụdị abụọ ahụ.
Dose ukpụhọde
Nsonaazụ
Ihe ngbanwe
Nchekwa	Nwee nchedo site na ọkụ, okpomoku na ekpomoku (> 30 Celsius C). Ekwesịrị idobe ya na igbe, a ga-eji okpu chekwaa insulin na mkpịsị mkpụrụ ogwu. Na ihu igwe na-ekpo ọkụ, a na-eji ngwaọrụ nkwụghachi pụrụ iche na-ebugharị Protafan. Ọnọdụ kachasị mma maka nchekwa ogologo oge (ruo izu 30) bụ shelf ma ọ bụ ọnụ ụzọ friji. N'ime ụlọ dị na ụlọ, Protafan na vial ya bidoro izu isii.

Mmekorita

Ọtụtụ ọgwụ hypoglycemic, monoamine oxidase inhibitors, angiotensin na - agbanwe enzyme na carbonic anhydrase, yana ụfọdụ ndị na - adịghị ahọrọ beta-mgbochi, sulfonamides, Bromocriptineanabolic steroid, tetracyclinesCyclophosphamide,Ketoconazole, Mebendazole,Clofibrate, Pyridoxine, Theophylline, Fenfluramine, ọgwụ nwere lithium nwere ike ịkwalite mmetụta hypoglycemic nke insulin.

N'otu oge ahụ, mgbochi mkpịsị ọnụ, thyroid nwere ike imebi mmetụta hypoglycemic ya. homonụglucocorticosteroids, thiazide diuretics, tricyclic antidepressants, heparinnnabata ọmiko Danazoleihe mgbochi calcium Clonidine, Diazoxide, Phenytoin, Morphine na nikotin.

Njikọ na Ihe ndozi nasalicylates nwere ike ime ka ike gharazie ikwusi ogwu a ike. Betafọdụ beta-na-egbochi mkpuchi nke hypoglycemia ma ọ bụ mee ka o sie ike iwepụ. Mmụba ma ọ bụ ibelata chọrọ insulin Octreotide naLanreotide.

Oge ihe omume

Ọnụego ntinye nke Protafan sitere na anụ ahụ dị n'okpuru ala n'ime ọbara n'ọrịa na ndị ọrịa nwere ọrịa shuga dị iche, yabụ agaghị ekwe omume ịkọ n'ụzọ ziri ezi mgbe insulin malitere ịrụ ọrụ. Nkezi data:

1. Site na ntụtụ gaa na ọdịdị nke homonụ n’ime ọbara, ihe dịka awa 1.5 gafere.
2. Protafan nwere ọrụ kachasị elu, n'ọtụtụ ndị ọrịa mamịrị ọ na - apụta na awa anọ 4 site n'oge nchịkwa.
3. Oge ngụkọta oge ana - eme ihe ruru awa iri abụọ na anọ. N'okwu a, ndabere nke oge ọrụ na dose achọrọ. Site na ntinye nke nkeji iri nke protafan insulin, a ga-ahụta mbelata mmịpụta ihe dịka elekere 14, nkeji 20 maka ihe dịka awa 18.

Usoro ịgba ọgwụ mgbochi

N'ọtụtụ ikpe na-arịa ọrịa shuga, nchịkwa abụọ nke Protafan ezuru: n'ụtụtụ na tupu ụra. Jectiontụtụ mgbede kwesịrị iji zuru ezu iji nwee glycemia n'abalị niile.

Esemokwu maka ụzọ ziri ezi:

• shuga n’ụtụtụ bụ otu ihe n’oge ụra
• enweghi hypoglycemia n'abalị.

Ọtụtụ mgbe, shuga ọbara na-ebili mgbe elekere 3 nke ụtụtụ gasịrị, mgbe mmepụta nke homonụ na-enwekarị ọrụ, na mmetụta nke insulin na-ebelata. Ọ bụrụ na ọnụ ọgụgụ kachasị elu nke Protafan ga-akwụsị na mbụ, ọ ga-ekwe omume nsogbu ahụ ike: hypoglycemia na-amaghị n'abalị na nnukwu shuga n'ụtụtụ. Iji zere ya, ịkwesịrị ịlee ọkwa shuga kwa oge na elekere 12 na 3. Enwere ike ịgbanwe oge mgbede mgbede, na-agbaso atụmatụ nke ọgwụ.

Ihe omume nke obere doses

Site n'ọrịa shuga 2dị nke abụọ, ọrịa shuga nke ụmụ nwanyị dị ime, na ụmụaka, na ndị okenye nọ na nri nwere obere carb, mkpa nke insulin nke NPH nwere ike ịbụ obere. Site na obere obere ọgwụ (ruo 7 nkeji), oge nke ihe Protafan nwere ike ịbụ naanị awa 8. Nke a pụtara na inpa abụọ ahụ ntuziaka a na-enye agaghị ezu, n'etiti etiti shuga n'ọbara ga-amụba.

Enwere ike ịhapụ nke a site na ịgbanye insulin insulin ugboro atọ kwa awa 8 ọ bụla: a na-enye ntụtụ nke mbụ ozugbo ịmụrụ anya, nke abụọ n’oge nri ehihie na insulin mkpụmkpụ, nke atọ, nke kachasị ukwuu, tupu ị lakpuo ụra.

Nyocha banyere ọrịa mamịrị, ọ bụghị mmadụ niile na-eme nke ọma n’ị nweta ezigbo ụgwọ maka ọrịa shuga n'ụzọ dị otu a. Mgbe ụfọdụ ọgwụ ụra abalị na-akwụsị ịrụ ọrụ tupu ịmụrụ anya, yana shuga n'ụtụtụ dị elu. Thebawanye dose ahụ na-eduga n'ịba ụba insulin na hypoglycemia. Onlyzọ ọ ga - esi pụta n'ọnọdụ a bụ ịgbanye insulin analogues na ogologo ọrụ.

Ihe iri nri

Ndị na-arịa ọrịa shuga na-agwọ insulin na-abụkarị ndị a na-akọ ka ọ bụrụ insulin. Short dị mkpa iji belata glucose na-abanye n'ọbara nke nri. A na-ejikwa ya iji dozie glycemia. Na Protafan, ọ ka mma iji obere nkwadebe nke otu onye na - emepụta ihe - Actrapid, nke dịkwa na vials na katridges maka mkpịsị mkpụrụ ogwu.

Oge nchịkwa nke insulin Protafan anaghị adabere na nri n'ụzọ ọ bụla, ihe dị ka otu oge n'etiti nsị zuru ezu. Ozugbo ịhọrọ oge dabara adaba, ịkwesịrị ịgbaso ya mgbe niile. Ọ bụrụ na ọ dabara na nri, enwere ike ịkwụ ụgwọ Protafan na insulin dị mkpụmkpụ. N'otu oge ịgwakọta ha n'otu sirinji bụ ihe a na-achọghị, ebe okwesiri imehie uzo na iwelata nwayọ n’ọkpụkpụ hormone.

Ikike dị ukwuu

Na shuga mellitus, ịkwesịrị ịbanye insulin dị ka a chọrọ iji mee ka glucose dị ọcha. Ntụziaka maka ijibebeghị ọgwụ kacha ike. Ọ bụrụ na ego ziri ezi nke protafan insulin na-eto, nke a nwere ike igosipụta nguzo insulin. Na nsogbu a, ị ga-agakwuru dọkịta gị. Ọ bụrụ na ọ dị mkpa, ọ ga-edenye ọgwụ na-eme ka ihe ahụ na - eto homonụ.

Iji Oge ime

Ọ bụrụ na enwere ọrịa shuga, ọ gaghị ekwe omume ị nweta ọrịa nkịtị nkịtị naanị site na nri, a na-enye ndị ọrịa ọgwụ insulin. A na-ahọrọ ọgwụ na ọgwụ ya karịsịa nke ọma, ebe ọ bụ na hypo- na hyperglycemia na-amụba ohere nke imerụ nwata ahụ. Anabataghị insulin Protafan maka oge afọ ime, mana n'ọtụtụ oge, ogologo oge analogues ga-adị irè karị.

Dọkịta nke Sciences Medical, Isi nke Institute of Diabetology - Tatyana Yakovleva

M na-amụ ọrịa shuga kemgbe ọtụtụ afọ. Ọ na-atụ ụjọ mgbe ọtụtụ mmadụ nwụrụ, nweekwa nkwarụ karịa n'ihi ọrịa shuga.

Emere m ngwa ngwa izisa ozi ọma - thelọ Ọrụ Nnyocha Ọgwụ Endocrinology nke Mahadum Ọgwụ nke Russia jisiri ike mepụta ọgwụ na-agwọ ọrịa shuga kpamkpam. N'oge a, ịdị irè nke ọgwụ a na-eru nso 98%.

Ozi ọma ọzọ: Ministri Ahụike echekwaala maka mmemme pụrụ iche nke na-akwụ ụgwọ ọgwụ dị elu. Na Russia, ndị ọrịa mamịrị ruo Mee Mee 18 (isonye) nwere ike inweta ya - Naanị 147 rubles!

Ọ bụrụ na ime tụụrụ ime n'ọrịa shuga nke 1, nwanyị ahụ wee kwụọ ụgwọ ọrịa ahụ Protafan, ọgwụ agbanweghị ya.

Breastfeu ara ara na usoro insulin. Protafan agaghị emerụ ahụike nwata ahụ. Insulin na-abanye n'ime mmiri ara ehi na obere ntakịrị, mgbe nke ahụ gasịkwara nke ahụ, ọ na-agbazekwa na usoro nri nke nwa ahụ, dịka protein ọ bụla.

Mmeghachi omume ọjọọ

Mmetụta dị n’akụkụ ọgwụgwọ bụ hypoglycemia. Ọ nwere ike ime mgbe ọnụọgụ ọgwụ karịrị insulin ahụike nke onye ọrịa. Dika ihe omumu banyere ogwu, ya na data banyere iji ogwu a ka eweputara ya na ahia, onodu a na - ebunye hypoglycemia di iche iche n’etiti ndi oria, n’usoro uzo ogwu di iche na nke njikwa glycemic.

Na mbido insulin ọgwụ, enwere ike ịhụ njehie ntụgharị, edema na mmeghachi omume na saịtị ịgba ntụtụ (mgbu, redness, urticaria, mbufụt, ọnya ahụ, ọzịza na itching na saịtị ịgba ntụtụ). Mmeghachi omume ndị a na-adịkarị. Ọganiihu ngwa ngwa na nchịkwa glucose ọbara nwere ike iduga n'ọnọdụ nwesigharị ọnya ụma. Njikwa glycemic nke ọma nwere ogologo oge na-ebelata ihe ọghọm nke ọrịa mamị retinopathy mamịrị. Agbanyeghị, ịbawanye uru nke insulin iji rụọ ọrụ ngwa ngwa iji glycemic njikwa nwere ike ime ka iwe iwe nke ọrịa mamị retinopathy nwa oge.

Dika ihe omumu banyere ogwu, ihe ndi a bu ihe ojoo na udiri oge site na usoro ihe ndi mmadu na ndi ozo.

Dika ugboro ugboro, ihe ndị a mere na-ekewa ndị na-eme oge (≥1 / 10), ọtụtụ mgbe (≥1 / 100 ruo 1/1000 ka 1/10000 to M NM Penfil ® n'oge a na-enye nwa adịghịkwa ahụ, ebe ọ bụ na ọgwụgwọ nne anaghị etinye nwa ahụ n'ihe ọ bụla. Agbanyeghị, ọ nwere ike ịdị mkpa idozigharị usoro na nri maka nne.

Nhazi insulin nke biosynthetic mmadụ dị mma ma dị mma n'ịgwọ ọrịa shuga na ụmụaka na ndị nọ n'afọ iri na ụma dị iche iche. Mkpa insulin kwa ụbọchị na ụmụaka na ndị nọ n’oge uto na-adabere n’usoro ọrịa ahụ, ibu ahụ, afọ, nri, mmega ahụ, ogo nguzogide insulin na ogo nke mgbatị afọ.

Njirimara ngwa

Ọgwụ ezughị ezu ma ọ bụ ịkwụsị ịgwọ ọrịa (ọkachasị ụdị nke ịrịa ọrịa shuga) nwere ike ibute hyperglycemia . Ọtụtụ mgbe, mgbaàmà mbụ nke hyperglycemia na-amalite nwayọọ nwayọọ karịa ọtụtụ awa ma ọ bụ ụbọchị. Ndị a gụnyere akpịrị ịkpọ nkụ, ure ugboro ugboro, ọgbụgbọ, vomiting, ụra, akpịrị na akpọnwụ akpịrị, akpịrị ịkpọ nkụ, agụụ, na isi nke acetone na ikuku nwere oke.

Diabetesdị ọrịa shuga m, hyperglycemia, nke a na-agwọghị, na-eduga na ketoacidosis mamịrị, nke nwere ike ịnwụ.

Hypoglycemia nwere ike ibute insulin dị elu dabere na mkpa insulin dị.

Iri nri ma ọ bụ imega ahụ́ ọ bụla ị na-atụghị anya ya nwere ike iduga hypoglycemia.

Ndị ọrịa emeela ka ọ dịkwuo mma ịchịkwa ọkwa glucose ọbara n’ihi ọgwụgwọ insulin na-agba ike nwere ike ịchọpụta mgbanwe na mgbaàmà ha na-emebu, ihe na-ebute hypoglycemia, nke e kwesịrị ịdọ aka na ntị tupu oge eruo.

Ihe ịrịba ama nke ịdọ aka na ntị nwere ike apụ n'anya na ndị ọrịa nwere ọrịa shuga ogologo oge.

Ntugharị onye ọrịa na ụdị ọzọ ma ọ bụ ụdị insulin na-adị n'okpuru nlekọta ahụike siri ike. Mgbanwe na ịta, ụdị (onye nrụpụta), ụdị, insulin (mmadụ ma ọ bụ ihe ana insulin) na / ma ọ bụ usoro mmepụta nwere ike ime ka mmegharị insulin dị mma. Ndị ọrịa ebugharị na instafan ® NM Penfil ® nwere ụdị insulin ọzọ nwere ike ịchọ mmụba nke ọnụ ọgụgụ ịgba ọgwụ kwa ụbọchị ma ọ bụ mgbanwe mgbanwe na usoro onyunyo tụnyere insulin ha na-ejikarị. Mkpa nke ịhọrọ nhọrọ nwere ike ibilite ma n'oge nchịkwa mbụ nke ọgwụ ọhụrụ, yana n'ime izu ole na ole ma ọ bụ ọnwa mbụ nke iji ya.

Mgbe ị na-eji ọgwụ insulin ọ bụla, mmeghachi omume nwere ike ime na ebe injection, nke nwere ike ịgụnye ihe mgbu, redness, itching, hives, breeze, ọnya na ọnya. Changinggbanwegharị oge irighiri mmiri n'otu mpaghara nwere ike belata ma ọ bụ gbochie omume mmeghachi omume ndị a. Mmeghachi omume na-apụkarị mgbe ụbọchị ole na ole ma ọ bụ izu gasịrị. N'ọnọdụ ndị a na-adịghị ahụkebe, mmeghachi omume na saịtị ịgba ahụ nwere ike ịchọ ịkwụsị ọgwụgwọ na Protafan ® NM Penfil ®.

Tupu njem oge mgbanwe, ndị ọrịa kwesịrị ịkpọtụrụ dọkịta, ebe ọ bụ na nke a na-agbanwe usoro inje insulin na ị foodụ nri.

Ekwesịrị iji insulin insulin mee ihe na nfuli insulin maka nchịkwa insulin nke nwere ogologo oge.

Njikọ nke thiazolidinediones na ngwaahịa insulin

Mgbe ejiri thiazolidinediones na insulin, a kọpụtawo ikpe metụtara obi nkụchi, ọkachasị ndị ọrịa nwere ihe ọghọm maka nkụchi obi. Ekwesịrị ịtụle nke a mgbe ị na-ede akwụkwọ ọgwụgwọ yana ngwakọta nke thiazolidinediones na insulin. Site na iji ọgwụ ndị a jikọtara ọnụ, ndị ọrịa kwesịrị ịnọ n'okpuru nlekọta nke dọkịta maka mmepe nke ihe ịrịba ama na mgbaàmà nke ọrịa obi ọrịa, oke ibu na ihe omume edema. N'ọnọdụ ọ bụla na-emebi obi na arụ ọrụ obi, a ga-akwụsị ịgwọ ya na thiazolidinediones.

Ikike iji metụta ọnụego mmeghachi omume mgbe ị na-anya ụgbọala ma ọ bụ usoro ndị ọzọ

Nzaghachi onye ọrịa na ike itinye uche ya nwere ike ịmetụta hypoglycemia. Nke a nwere ike ịbụ ihe egwu dị na ọnọdụ ebe ikike ndị a dị oke mkpa (dịka ọmụmaatụ, mgbe ị na-anya ụgbọala ma ọ bụ na-arụ ọrụ na usoro ndị ọzọ).

A dụrụ ndị ọrịa ọdụ ka ha mee ihe iji gbochie hypoglycemia tupu ha akwọ ụgbọala. Nke a dị ezigbo mkpa maka ndị ọrịa daa mba ma ọ bụ ndị na - anọghị na mgbaàmà nke hypoglycemia ma ọ bụ ngosipụta nke hypoglycemia ugboro ugboro. N'ọnọdụ ndị dị otú ahụ, o kwesịrị ịdị mkpa ịnya ịnya ụgbọ ala.

Ọdịiche nke analogues insulin

Ogologo insulin analogues, dị ka Lantus na Tujeo, enweghị ọnụ ọgụgụ kasị elu, a na-anabata ya karịa ka o nwere ike ịkpalite nfụkasị. Ọ bụrụ na onye na-arịa ọrịa shuga enweghị ọrịa hypoglycemia ma ọ bụ nke shuga na-enweghị ihe ọ bụla pụtara ìhè, a ga-eji Protafan dochie insulins oge ọhụụ.

Ihe ọghọm ha dị ukwuu bụ ụgwọ ha dị elu. Ọnụahịa nke Protafan bụ ihe ruru 400 rubles. maka otu karama na 950 maka mbukota ogwe maka mkpagide sirinji. Insulin analogues nwere ihe ruru okpukpu atọ karịa ọnụ.

Gbalia imuta! You chere na ị takingụ ọgwụ na insulin bụ naanị ụzọ eji egbochi shuga? Ọ bụghị eziokwu! Nwere ike ịchọpụta nke a n'onwe gị site na ịmalite iji ya. gụkwuo >>

Njirimara physicochemical nke nkiti

ihe nkwụchi nke ọcha, nke eji eme ka ọchichaa na-acha ọcha na nke na-enweghị ụcha ma ọ bụ nke na-enweghị ụcha na-enweghị njigide na-akwụ ọtọ, a na-eji iweghachi nwayọ were ịma jijiji. Mgbe enyocha microscope, urukpu ahụ yiri kristal nke ụdị dị ogologo, ogologo nke kristal bụ 1-20 microns.

Ọnọdụ nchekwa

Chekwaa na refrjiraeto na okpomọkụ nke 2 Celsius - 8 Celsius C. Ejikwala.

Debe katalọgụ na nkwakọ ngwaahịa nke abụọ maka nchebe pụọ na ọkụ.

Mgbe emepechara: jiri n'ime izu isii. Echekwala na friji. Na-echekwa na okpomọkụ agaghị akarị 30 Celsius.

Ejila oge emechachara edepụtara na ngwugwu.

Ekwela ka ụmụaka ghara iru ya.

Otu kọọlụ iko (ụdị 1) nke nwere milimita 3, nke bụ piston roba (bromobutyl roba) ma jiri roba diski (bromobutyl / polyisolorida roba) mechie. Akwukwo ahihia nwere ezigbo iko maka agwakọta. 5 katọn n’otu katọn.

Njirimara nke ogwu

Ọgwụ bụ nkwusioru ewepụtara n’okpuru anụahụ.

Otu, ihe na-arụ ọrụ:

Isulin insulin-mmadu semisynthetis (semisynthetic mmadu). O nwere nkezi oge ihe. Protafan NM bụ contraindicated na: insulinoma, hypoglycemia na hypersensitivity na-arụ ọrụ.

Etu esi ewere na n’ime usoro onunu ogwu?

A na-etinye insulin otu ugboro ma ọ bụ ugboro abụọ n'ụbọchị, ọkara otu awa tupu nri ụtụtụ. N'okwu a, ebe a ga-eme inje, ọ ga-agbanwe ya mgbe niile.

Ekwesịrị ịhọrọ dose ahụ maka onye ọrịa ọ bụla n'otu n'otu. Olu ya na-adabere n’otú glucose dị n’ime mmamịrị na ọbara ọbara, yana n’omume nke otu ọrịa. N'ụzọ bụ isi, a na-enye ọgwụ ahụ otu oge kwa ụbọchị ma ọ bụ 8-24 IU.

N'ime ụmụaka na ndị okenye nwere insulin, a na-ebelata ogo ahụ ka ọ bụrụ 8 IU kwa ụbọchị. Ma maka ndị ọrịa nwere oke mmetụ uche, dibịa na-aga ahụ nwere ike ịkọtara otu ọgwụ karịrị 24 IU kwa ụbọchị. Ọ bụrụ na ọgwụ kwa ụbọchị karịrị 0.6 IU kwa kilogram, mgbe ahụ ọgwụ ọgwụ abụọ na-ahụ maka ọgwụ abụọ, nke a na-eme n'ebe dị iche iche.

Ndị ọrịa na-anata 100 IU ma ọ bụ karịa kwa ụbọchị, mgbe ha na-agbanwe insulin, ha ga-anọrịrị na-elekọta ndị dọkịta mgbe niile. Should ga-eji dochie ọgwụ ọzọ site na ilele ọkwa glucose ọbara.

Etu esi eleghara ịdoụbiga mmanya ókè?

Ọ bụrụ na onye ọrịa nọ n'ọnọdụ ahụ, mgbe ahụ dọkịta deputara dextrose, nke a na-enye site na dropper, intramuscularly ma ọ bụ intravenously. A na-ejikwa Glucagon ma ọ bụ usoro dextrose hypertonic deprorose.

A bụrụ na mmepe nke hypoglycemic coma, 20 ruo 40 ml, i.e. Mpempe 40% dextrose ruo mgbe onye ọrịa na-apụta site na Coma.

1. Tupu i were insulin site na ngwugwu ahụ, ịkwesịrị ịlele na ihe ngwọta dị n'ime karama ahụ nwere agba agba. Ọ bụrụ n'igwe ojii, mmiri ma ọ bụ akụkụ ala ọzọ ka ahụrụ, amachibidoro ya.
2. Okpomoku nke ogwu tupu ochichi kwesiri ibu ulo.
3. Na ọnụnọ nke ọrịa na-efe efe, ịrụ ọrụ nke gland thyroid, ọrịa Addiosn, ọdịda akụrụ na-adịghị ala ala, hypopituitarisis, yana ndị ọrịa mamịrị agadi, usoro insulin kwesịrị ka edozi ya n'otu n'otu.

Ihe na - akpata hypoglycemia nwere ike ịbụ:

• nnyefere
• vomiting
• ọgwụ ịgbanwe
• ọrịa na-ebelata mkpa insulin (ọrịa imeju na akụrụ, hypofunction nke thyroid gland, pituitary, adrenal cortex),
• Emeghị ihe oriri,
• nmekorita ya na ogwu ndi ozo
• afọ ọsịsa
• anụ ahụ arụ,
• mgbanwe nbanye saịtị.

Mgbe ị na-ebufe onye ọrịa si insulin anụmanụ n’ime insulin mmadụ, mbelata nke glucose ọbara nwere ike pụta. Ntughari na insulin nke mmadụ kwesiri ịbụ ihe ziri ezi site na elele ahụike, ekwesịrị ịme ya n'okpuru nlekọta dọkịta.

N'oge ịmụ nwa na mgbe a mụsịrị nwa, enwere ike belata mkpa nke insulin. N’oge ị na-agba ara, ịkwesịrị ilebara nne gị anya ọtụtụ ọnwa, ruo mgbe ọ ga-egbo mkpa insulin.

Ihe nwere ike ime ka ọrịa hypoglycemia na-arịa ọrịa nwere ike ime ka mmadụ nwekwuo ike ịnya ụgbọ ma nwee usoro na igwe.

Site n'enyemaka nke shuga ma ọ bụ nri nwere nnukwu ọdịnaya nke carbohydrates, ndị ọrịa mamịrị nwere ike ịkwụsị ụdị hypoglycemia dị nro. Ọ bụ ihe amamihe dị na ya na onye ọrịa a nwere shuga dịkarịa ala 20 mgbe niile.

Ọ bụrụ na eyigharị hypoglycemia, ọ dị mkpa ịgwa dọkịta onye ga-eme mgbanwe ọgwụgwọ ahụ.

N’ime afọ ime, a ga-elele mbelata (1 ọkara) ma ọ bụ ịrị elu (2-3 ọkara) nke ahụ ịchọrọ insulin.