Ọgwụ Mefarmil: ntuziaka maka ojiji

Ọgwụ ahụ bụ otu nke biguanides, ihe dị n'ọrụ bụ dimethyl biguanide. Nweta ya na osisi Galega officinalis. Metformin na - egbochi ọrụ glucose site na umeji (usoro gluconeogenesis), wee si belata ọkwa shuga dị n'ọbara. N'akụkụ a, ọgwụ a na -ekwupụta uche nke ndị na - anabata insulin, na - eme ka mmụba ya dịkwuo mma, na - akwalite nzere nke faty acid, na - eme ka glucose na - ahụkarị ike, ma na - ebelata mmịcha ya na traktị.

Ngwá ọrụ ahụ na-enyere aka belata homonụ na-akpali akpali n'ime ọbara ọbara, belata cholesterol na obere lipoproteins dị ala, si otú a na-egbochi mgbanwe mgbanwe pathologies na arịa ọbara. Normalizes coagulability ọbara, melite ya rheological Njirimara, si otú ahụ na-ebelata ihe ize ndụ nke thrombosis.

Nyocha nke Endocrinologists nke Metformin na-akwado ozi na ọ na-enye aka n'ibu oke ibu.

Analogs nke Metformin

Metformin analogues gụnyere ọgwụ ndị a: Glucofage, Metformin-BMS, Metformin hydrochloride, Metformin-vero, Metformin-Richter, Formmetin, Formin Pliv, Gliformin, Glucofag, Vero-Metformin Novoformin, Metospanin. Metfogamma, Siofor, Glycomet, Dianormet, Orabet, Bagomet, Gliminfor, Glycon.

Site na echiche nke usoro ọgwụ, anaform nke Metformin bụ insulin.

Ihe ngosi maka ojiji

A na-egosi ojiji nke Metformin na ọgwụgwọ ụdị ọrịa shuga 2 nke nwere ọrụ ezigharịrị echekwara, yana ọnọdụ ọria mamịrị. Ihe ngosipụta a kapịrị ọnụ maka iji ya bụ shuga 2dị nke Abụọ, yana oke ibu.

A na-ejikwa ya dị ka akụkụ nke usoro ọgwụgwọ siri ike na ọgwụgwọ nke oke ibu nke visceral.

N'oge a na-eme ya na usoro ọgwụgwọ, nyocha nke Metformin dị mma nke na mgbe ha nyochasịrị ọgwụ na-enyocha ya, na 2007 ka akwadoro ọgwụ ahụ maka omume ụmụaka maka ọgwụgwọ nke ọrịa shuga 1, dị ka ihe jikọrọ ọgwụ insulin.

Ntuziaka maka iji Metformin

A na-ewere mbadamba Metformin nke ọma mgbe ha risịrị nri, na-a drinkingụ nnukwu mmiri. Usoro ọgwụgwọ mbụ na nke mbụ bụ 1000 mg kwa ụbọchị, ihe karịrị izu 1-2 ka ọgwụ ji nke nta nke nta na-abawanye, a na-agbanwe uru ya n'okpuru njikwa nke nyocha ụlọ nyocha banyere ọkwa glucose dị n'ọbara. Ogo kachasị anabata bụ 3000 mg kwa ụbọchị. Enwere ike iji ọgwụ a na-eme kwa ụbọchị n'otu oge, mana na mbido ọgwụgwọ, n'oge mmegharị ahụ, a na-atụ aro ịkewa ya n'ime usoro 2-3, nke na-enyere aka belata mmetụta n'akụkụ ọgwụ na eriri afọ.

A na-ahụta ọgwụ kachasị na plasma ọbara 2,5 awa 2.5 mgbe nchịkwa gasịrị, mgbe awa 6 gachara ọ ga-agbada. Ka ụbọchị 1-2 gachara ị regularụ ọgwụ, emeela ka itinye ọgwụ mgbe niile na ọbara, dịka nyocha si kwuo, Metformin bidoro inwe mmetụta pụtara ìhè izu abụọ mgbe mmalite nke nchịkwa.

Site n'iji Metformin na insulin jikọtara ọnụ, ọ dị mkpa ka a na-ahụ maka nlekọta ahụike, yana nnukwu insulin n'ụlọ ọgwụ.

Nsonaazụ

Mgbe ejiri ntuziaka ndị a na-eme, a na-anabata Metformin nke ọma site na ndị ọrịa, ọ naghị ebutekarị nsonaazụ. Ọ bụrụ na enwere ụfọdụ, mgbe ahụ, dịka iwu, ha na-ejikọ ya na mmadụ ị intoụ ọgwụ ọ individualụ individualụ, ma ọ bụ na mmekọrịta ya na ọgwụ ndị ọzọ, ma ọ bụ yana oke ịsụ ọgwụ.

Site na nyocha, Metformin na-ebutekarị nsogbu nri, gosipụtara n'ụdị dyspepsia n'otu ụdị ma ọ bụ ọzọ, dị ka otu n'ime akara nke lactic acidosis. A na - ahụkarị ihe ịrịba ama ndị dị na mbido ọgwụgwọ nke ọgwụ, ma gafee oge oge mmegharị ahụ. Dịka ntuziaka ahụ si dị, a ga-eji Metformin mee ihe na nke a, na ọgwụ lactic acidisis siri ike, a na-akagbu ọgwụ ahụ.

Site n'iji ogologo oge, Metformin na-enye aka na mmebi nke mgbanwe nke vitamin B12 (cyancobalamin), na-egbochi ịmịkọrọ ya na eriri afọ, nke nwere ike ibute mgbaàmà Bemensia ana-enweghị nsogbu. Ọnọdụ a chọrọ mgbazi ọgwụ.

Metformin Contraindications

A na-egosi contraindications ndị a na ntuziaka Metformin:

• Lactic acidosis dị ugbu a ma ọ bụ nke gara aga
• Ọnọdụ precomatous
• Enweghị mgbochi na akụkụ ọ bụla nke ọgwụ ahụ,
• Ọrụ akụrụngwa na-arụ ọrụ, yana ọrịa na-efe efe nke nwere ike ibute ụdị mmebi a,
• Adrenal ezughi oke,
• Imeju imeju
• Ọrịa mamịrị
• Ọnọdụ niile na-akpata akpịrị ịkpọ nkụ (vomiting, afọ ọsịsa) na hypoxia (ujo, ọdịda cardiopulmonary).
• Mmanya Okwesiri iburu n’uche na obuna otu mmekorita nke Metformin na mmanya nwere ike ibute nsogbu nke ukwu.
• Ọrịa na-arịa ọrịa na-efe efe na nnukwu ọrịa, yana fever,
• Ọrịa na-adịghị ala ala na ngbanwe,
• Nnukwu ụlọ ịwa ahụ na mmezi ahụ,
• Ara

Oge ime, dị ka nwata, anaghị elele contraindication zuru oke maka ị theụ ọgwụ a, ebe ọ bụ na ọ ga-ekwe omume ịdebere Metformin maka ọgwụgwọ nke ọrịa mmekpa ahụ na nke ụmụaka, na agbanyeghị, n'ọnọdụ ndị a, usoro ọgwụgwọ na-apụta kpam kpam n'okpuru nlekọta ahụike.

Ntụziaka pụrụ iche

Site na Metformin monotherapy, enweghị ihe ize ndụ nke ịmalite hypoglycemia, a naghị etinye ụdị ihe ize ndụ ahụ na usoro mgbagwoju anya nke ọrịa shuga, nke a ga-adọrịrị ịdọ aka ná ntị banyere ya. Amachibidoro ị thisụ ọgwụ a yana ọgwụ redio introvascular nwere iodine. Ojiji ejiri Metformin yana ọgwụ ọzọ chọrọ dibia bekee. N'oge ịwa ahụ, a na-akagbu ọgwụgwọ ọgwụ maka ụbọchị 2-3 nke oge ọmụmụ. Ntụziaka Metformin na-edobe usoro nri n'oge oge ọgwụgwọ, nke na-ezere ọnụ ọgụgụ dị nkọ na ịdaba na glucose ọbara, na-eme ka ọnọdụ dị mma.