Ọrịa mamịrị insipidus

Ọrịa mamịrị insipidus- ọrịa nke ezughi oke ma ọ bụ nke ezughi oke nke mmiri ọgwụ hypothalamic vasopressin (ADH-antidiuretic hormone).

Amaghị ugboro ole ọrịa ahụ na-eme, na-apụta na 0,5-0.7% nke ndị ọrịa endocrine.

Nhazi nke mwepụta vasopressin na nsonaazụ ya

Vasopressina na - ekekọta ikuku na oxygentocin na supraoptical na paraventicular nuclei nke hypothalamus, a na - etinyekọta ya na granules nke kwekọrọ na neurophysines ma na - ebugharị ya na axons banye na ogwe mmerụ ahụ (neurohypophysis), ebe a na-echekwa ya ruo mgbe ewepụtara ya. Ihe ndozi nke vasopressin na neurohypophysis na mkpali na-adịghị ala ala nke mmiri nzuzo ya, dịka ọmụmaatụ, na ịhapụ ị drinkingụ mmanya ogologo oge, belata nke ukwuu.

Ọ bụ ọtụtụ ihe kpatara nzuzo nke vasopressin. Ihe kachasị mkpa n’ime ha bụ osmotic ọbara mgbali, i.e. osmolality (ma ọ bụ osmolarity) nke plasma. N'ime hypothalamus ihu, dị nso, mana ọpụpụ na iche nuclei, ọ dịosmoreceptor. Mgbe plasma osmolality dị obere, ma ọ bụ uru ọnụ ụzọ, ntinye vasopressin dị na ya pere mpe. Ọ bụrụ na plasma osmolality gafere n'ọnụ ebe a, osomenti na-achọpụta nke a, ntinye vasopressin na-agbadata nke ukwu. Usoro osmoregulation na-aza ajụjụ nke ukwuu nke ukwuu. Ejikọtara obere mmụba na osmoreceptorsite na afọ.

Ihe osmoreceptor anaghị enwe mmetụta na-enweghị isi na plasma dị iche iche. Sodium(Na +) na ntụpọ ya bụ ihe mkpali kachasị ike nke osmoreceptor na secretion vasopressin. Na na anions ya na-ekpebi 95% nke plasma osmolality.

Nnukwu nke ọma na-akpali nzuzo nke vasopressin site na osmoreceptor sucrose na mannitol. Ọgwụ glucose adịghị akwalite osmoreceptor, dịkwa ka urea.

Ihe kachasị ịtụkwasị obi na-atụ aro na-akpali mkpịsị vasopressin bụ ikpebiNa+na plasma osmolality.

Ọbara vasopressin na-emetụta olu obara na obara obara. A na - ahụta mmetụta ndị a site na baroreceptors dị na atria na archic arch. Baroreceptor na-akpali site na eriri otu na-aga na stem ụbụrụ dịka akụkụ nke akwara na glossopharyngeal irighiri akwara. Site na azuokpo ụbụrụ, a na-ebunye akara na neurohypophysis. Mbelata ọbara mgbali elu ma ọ bụ mbelata olu olu (dịka ọmụmaatụ, ọbara ọgbụgba) na - akpali mkpali nke vasopressin. Mana sistemụ a anaghị enwe mmetụta ọsọ ọsọ karịa osmotic na-enyere osoroceptor.

Otu n'ime ihe ndị dị irè na-akpali ntọhapụ nke vasopressin bụ ọgbụgbọN'onweghi anya, ma obu ihe nlere mere ya (ujo, mmanya, nikotin, apomorphine). Ọbụna na ọgbụgbọ, na-enweghị ọgbụgbọ, ọkwa vasopressin na plasma na-arị elu ugboro 100-1000!

Ọ dịchaghị mma karịa ọgbụgbọ, mana ọ bụ ihe mkpali kwa oge maka vasopressin zoro ezo bụ hypoglycemia,ọkachasị nkọ. Mbelata ọkwa glucose site na 50% nke ọkwa mbụ n’ime ọbara na-eme ka ọdịnaya vasopressin nwee ugboro 2-4 na mmadụ, yana oke na- ugboro 10!

Na-eme ka mmiri ọgwụ vasopressin na-abawanye sistemụ renin-angiotensin. Amabeghị ọkwa nke renin na / ma ọ bụ angiotensin iji kpalie vasopressin.

E kwenyekwara na enweghị nchekasị enweghị atụihe na-akpata dị ka ihe mgbu, mmetụta uche, imega ahụ, na-eme ka ihe nzuzo nke vasopressin dịkwuo elu. Agbanyeghị, ọ ka amabeghị etu nchekasị na-esi mee ka mmiri ọgwụ vasopressin nwee ike - n'ụzọ ụfọdụ pụrụ iche, ma ọ bụ site na wedata ọbara mgbali na ọgbụgbọ belata.

Gbochie nzuzo nke vasopressinihe vaskụla na-arụ ọrụ, dịka norepinephrine, haloperidol, glucocorticoids, opiates, morphine. Mana amabeghị ma ihe ndị a niile a na-eme n’etiti, ma ọ bụ site n’ịbawanye mgbali ọbara na olu.

Ozugbo ọ dị n’usoro sistem, a na-ekesa vasopressin ngwa ngwa n’akuku mmiri ọzọ. A na-enweta nguzozi n’etiti intra- na extravascular oghere n’ime nkeji 10-15. Inactivation nke vasopressin na-aputa ihe tumadi na imeju na akụrụ. Ebibila akụkụ dị nta na mmamịrị ahụ.

Mmetụta.Mmetụta ndu kachasị mkpa nke vasopressin bụnchekwa mmiri n’ime ahụsite n’ibelata nsị mmamịrị. Ebumnuche nke itinye n'ọrụ ya bụ epithelium nke akụrụ anya na / ma ọ bụ mkpo mkpụkọta nke akụrụ. Na enweghị vasopressin, mkpụrụ ndụ mejupụtara akụkụ nke nephron ahụ bụ ihe mgbochi na-enweghị ike igbochi mgbasa nke mmiri na ihe ndị na-emebi mmiri. N'okpuru ọnọdụ ndị dị otú ahụ, hypotonic filtrate guzobere n'akụkụ akụkụ ka ukwuu nke nephron na-agafe ọdụ ma na-anakọta mkpo na-enweghị mgbanwe. Ike a kapịrị ọnụ (mmụkọ) nke mmamịrị dị ala dị ala.

Vasopressin na - eme ka ngwụcha nke distal na ịnakọta tubu maka mmiri. Ebe ọ bụ na mmiri na-amịghachi na-enweghị ihe osmotic, nsonaazụ nke osmotic ihe dị n'ime ya na-abawanye, na olu ya, i.e. ọtụtụ na-ebelata.

Enwere ihe akaebe na homonụ anụ ahụ mpaghara, prostaglandin E, na-egbochi ihe vasopressin n'ime akụrụ. N'aka nke ya, ọgwụ mgbochi ọgwụ na - abụghị ọgwụ steroidal (dịka ọmụmaatụ, Indomethacin), nke na-egbochi njikọta nke prostaglandins na akụrụ, na-abawanye mmetụta nke vasopressin.

Vasopressin na - arụkwa ọrụ dị iche iche nke sistem, dịka akwara ọbara, eriri afọ, akwara obi.

Obi mgbawana-arụ ọrụ dị ka mgbakwunye dị mkpa maka ọrụ antidiuretic nke vasopressin. Thirst bụ mmata nke mkpa mmiri dị.Ọ bụ ọtụtụ ihe na-akpata vasopressin na-akpali mkpali. Nke kachasị dị irè n’ime hahypertonic gburugburu.Oke plasma osmolality zuru oke, ebe enwere mmetụta akpịrị ịkpọ nkụ, bụ 29mmg / n'arọ. Site n'ọbara dị otu a, a na-ahapụ mmamịrị na itinye uche n'ihe kachasị. Thirst bụ ụdị breeki, ọrụ bụ isi ya bụ iji gbochie akpịrị ịkpọ nkụ, nke karịrị ikike ịgba ụgwọ nke usoro antidiuretic.

Ezigbo ga - amụba ngwa ngwa na pesma na ossolality nke plasma ma bụrụ nke a na - agaghị edili mgbe osmolality bụ naanị 10-15 anwụrụ / kg karịrị ọkwa ọnụ ụzọ. Iri mmiri bụ ihe mbido akpịrị ịkpọ nkụ. Mbelata nke olu ọbara ma ọ bụ ọbara mgbali na-akpata akpịrị ịkpọ nkụ.

Mmepe nke ụdị ọrịa insipidus dị n'ọbara dị na mmeri nke akụkụ dị iche iche nke hypothalamus ma ọ bụ nke na-esote pituitary, i.e. akwara ozi Ihe ndị mere nwere ike ịgụnye ihe ndị a:

na-efe efennukwu ma ọ bụ nke na-adịghị ala ala: flu, meningoencephalitis, ịba na-acha uhie uhie, pertussis, typhoid, sepsis, tonsillitis, ụkwara nta, syphilis, rheumatism, brucellosis, malaria,

ọnya ụbụrụ: ọghọm ma ọ bụ ịwa ahụ, ujo eletrik, mmerụ ọmụmụ n’oge ịmụ nwa,

hypothalamic ma ọ bụ pituitary tumo:metastatic, ma ọ bụ isi. Ọrịa cancer nke mammary na thyroid glands, bronchi metastases na pituitary gland ugboro ugboro. Mmebi site na ihe ndị dị na tumor na lymphogranulomatosis, lymphosarcoma, leukemia, janthomatosis sitere na ya (ọrịa Hend-Schuller-Crispen). Ọria mbu: adenoma, glioma, teratoma, craniopharyngioma (ọkachasị oge), sarcoidosis,

ọrịa endocrine:Simmonds, Skien, Lawrence-Moon-Beadl syndromes, pituitary dwarfism, acromegaly, gigantism, adinogenital dystrophy,

idiopathic:na 60-70% nke ndị ọrịa, ihe kpatara ọrịa ahụ ka amabeghị. N'ime ụdị idiopathic, ihe nnọchianya a ma ama nwere ọrịa mellitus na-akpata ọrịa, nke a na-achọpụta n'ọtụtụ ọgbọ. Ofdị ihe nketa bụ ihe na - agbanwe agbanwe,

autoimmune: mbibi nke nuclei nke hypothalamus dị ka nsonaazụ nke usoro akpaaka. Echere na ụdị a ga - ebilite na insipidus ọrịa idiopathic, ebe mkpụrụaka akpaaka ga - apụta mkpụrụ ndụ vasopressin.

Na gburugburuechekwara mbufụt vasopressin na-arịa ọrịa shuga, mana amamịghe nke ndị na-anabata akụrụ renyin tubule na homonụ belatara ma ọ bụ anọghị ya, ma ọ bụ ibibi homonụ nke imeju, akụrụ na Plasenta.

Nehrogenic ọrịa shuga insipidusa na-ahụkarị ụmụaka, ihe kpatara ya bụ akachaghị adị nke akwara nke akụrụ, (ma ọ bụ mmebi agbụrụ), ma ọ bụ mmebi nke nephron (amyloidosis, sarcoidosis, lithium poison, methoxyfluramine). ma ọ bụ belata uche nke renal tubule epithelium ndị na-anabata vasopressin.

Clinic nke ọrịa shuga insipidus

n'ihi akpiri kpọrọ nkụsite na mgbe o were nkwupụta ka ọfụma, ghara ịhapụ ndị ọrịa ka ọ ra n ’ehihie ma n’abalị. Mgbe ụfọdụ ndị ọrịa na-a litersụ mmiri 20-40 mmiri kwa ụbọchị. N'okwu a, enwere mmiri ị iceụ mmiri,

polyuriana urination ngwa ngwa. Mmamịrị ahụ na-egbuke egbuke, na-enweghị urochromes,

anụ ahụ na ucheadịghị ike,

nri ririifelataikekwe mmepeoke ibuọ bụrụ na insipidus ọrịa shuga na-etolite dị ka otu n'ime akara nke nsogbu hypothalamic bụ isi.

ọrịa dyspeptiksite na afọ - mmetụta nke oke, belching, mgbu na epigastrium, eriri afọ - afọ ntachi, eriri afọ - oke ume, mgbu mgbu hypochondrium,

nsogbu uche na nke mmetụta uche: isi ọwụwa, ahaghị nhatanha nke mmetụta uche, ehighị ụra nke ọma, belata ọrụ ụbụrụ, mgbakasị ahụ, anya mmiri, mmụọ mgbe ụfọdụ.

nsọ nwoke, na ụmụ nwoke - ikike.

Mmalite nke ọrịa ahụ nwere ike bụrụ nnukwu, na mberede, ọ naghị abụkarị nwayọ nwayọ, ihe mgbaàmà ya na-abawanye ka ọrịa ahụ na-akawanye njọ. Ihe na - akpata ya nwere ike ịbụ mmerụ ahụ ụbụrụ ma ọ bụ ụbụrụ, ọrịa na - ebute ịwa ahụ na ụbụrụ. Ọtụtụ mgbe, enweghị ike ịmata ihe kpatara ya. Mgbe ụfọdụ, a na-eme ka ihe nketa dị iche maka ọrịa shuga na-ehiwe ike.

akpụkpọ ahụ kpọrọ nkụ, belata salivation na sweating,

enwere ike belata ahu gi, odi nma ma obu nwekwuo

Ire na-akpọnwụ akpọnwụ n'ihi akpịrị ịkpọ nkụ, a na-ebelata ụsọ afọ n'ihi oke mmiri mmiri. Site na mmepe nke gastritis ma ọ bụ biliary dyskinesia, ịmụba uche na mgbu na palpation nke epigastrium na hypochondrium ziri ezi ga-ekwe omume,

Usoro akwara na akwara umeji, akwara anaghị ata ahụhụ,

Usoro urination: urination ugboro ugboro, polyuria, nocturia,

ihe ịrịba amaakpịrị ịkpọ nkụaru, ma oburu na mmiri aturu n’ime faina, nihi ihe ndia, adighi ejuputa - enweghi mmiri, na --eme nnwale site na “iri nri”, ma obu nnabata nke etiti akpiri ahu wedata:

adịghị ike n'ozuzu ya, isi ọwụwa, ọgbụgbọ, ọgbụgbọ ugboro ugboro, mmiri ị ,ụ mmiri,

ọbara mgbali, ihe mgbu, nsogbu uche uche

Nsogbu nke CCC: tachycardia, hypotension rue daa na coma,

ọbara ọgbụgba: mmụba n'ọtụtụ Hb, mkpụrụ ndụ ọbara uhie, Na + (N136-145 mmol / L, ma ọ bụ meq / L) creatinine (N60-132 mmol / L, ma ọ bụ 0.7-1.5 mg%),

ike ndọtị nwere mmerụ ahụ dị ala - 1000-1010, polyuria na-adịgide.

Ihe ndị a na -eme ka akpukpọ hyperosmolar mmiri bụ akparamagwa nke ọrịa shuga dị n'ọbara ụmụaka.

Nchoputadabere na njiri mara nke ọrịa shuga insipidus na laabu na ihe ọmụmụ:

Ike mmamịrị dị ala - 1000-1005

plasma hyperosmolarity,> 290 mosm / n'arọ (mmiri mmiri N280-296, ma ọ bụ mmiri mmol / kg),

hypoosmolarity mmamịrị, 155 meq / l (N136-145 meq / l, mmol / l).

Ọ bụrụ na ọ dị mkpa nlele:

Nnwale ahụ na-eri nri.A na-eme nnwale a n'ụlọ ọgwụ, oge ya na-abụkarị awa 6 ruo 6, yana ezigbo ndidi - awa iri na anọ. Enweghị mmiri mmiri adịghị enye. Nri kwesiri ibu protein. A na-anakọta urine kwa oge, a na-atụle olu na ike ndọrọndọrọ ọ bụla. A na-amata ịdị arọ anụ ahụ mgbe ọ bụla 1 lita nke mmamịrị wepụrụ.

Ikwu oke: enweghị nke mgbanwe dị omimi na oke mmamịrị na akụkụ abụọ na - enwe oke nke ahụ mmadụ na - egosi na - enweghị mkpali nke vasopressin endogenous.

Sample na iv nchịkwa nke 50 ml nke 2.5% ngwọtaNaCln’ime nkeji iri anọ na ise Site na insipidus nke ọrịa shuga, oke na njupụta mmamịrị adịghị agbanwe agbanwe. Site na polydipsia psychogenic, mmụba na osmotic plasma ịta ahụ na-akpali ngwa ngwa ntọhapụ nke vasopressin endogenous ma mmamịrị ewepụtara na-ebelata, ike ndọpụ ya nwere na-abawanye.

Nyocha na ntinye nke vasopressin nkwadebe - 5 I / O ma ọ bụ / m.Site na ezi insipidus ọrịa shuga, ọnọdụ ahụike na-emeziwanye, polydipsia na polyuria na-ebelata, osmolarity plasma na-ebelata, osmolarity mmamịrị na-abawanye.

Iche iche banyere ọrịa shuga insipidus

Dika isi ihe iriba ama nke oria insipidus - polydipsia na polyuria, oria a di iche site na otutu oria nke na-egosi na oria a: psychogenic polydipsia, diabetes mellitus, polyuria na-acho mkpuru akuko nke na adighi ala.

Ọrịa kansa na-efe efe nke Nephrogenic vasopressin insipidus (ma ọ bụ nke enwetara) bụ nke polyuria nwere ọdịiche aldosteronism, hyperparathyroidism na nephrocalcinosis, yana ọrịa malabsorption na enterocolitis na-adịghị ala ala.

Gịnị bụ ihe a

Ọrịa shuga insipidus bụ ọrịa na-adịghị ahụkebe (ihe dị ka mmadụ 3 n'ime 100,000) jikọtara ya na hypothalamus ma ọ bụ pituitary gland, nke polyuria mara (mpụta nke 6-15 lita nke mmamịrị kwa ụbọchị) na polydipsia (akpịrị ịkpọ nkụ).

Ọ na - eme n’etiti ndị nwoke na nwanyị, ma n’etiti ndị okenye na ụmụaka. Ọtụtụ mgbe, ndị na-eto eto dara ọrịa - site na afọ 18 ruo 25. A mara ọkwa banyere ọrịa nke ụmụaka nke afọ mbụ nke ndụ (A.D. Arbuzov, 1959, Sharapov V.S. 1992).

Ihe na-akpata ọrịa shuga insipidus

Ọrịa mamịrị insipidus bụ ọrịa na - akpata ụkọ vasopressin, ụkọ ya zuru oke ma ọ bụ nke na - akpata ya. Vasopressin (a na - egbochi homonụ antidiuretic) na hypothalamus ma, n'etiti ọrụ ndị ọzọ, ọ bụ ọrụ maka nhazi nke usoro urination. Dika odi, odi ka igbakowa udiri oria abuo a na ihe kpatara mbu: nkpuru ndu, enwetara, idiopathic.

N'ime ọtụtụ ndị ọrịa nwere ọrịa a dị ụkọ, a ka amataghị ihe kpatara ya. A na-akpọ ụdị shuga dị otú ahụ, ihe dị ka pasent 70 nke ndị ọrịa na-arịa ya. Mkpụrụ ndụ ihe nketa bụ ihe nketa. N'okwu a, insipidus ọrịa shuga na-egosipụta onwe ya oge ụfọdụ n’ime ezi na ụlọ na ruo ọtụtụ ọgbọ n’usoro.

Medicine na-akọwa nke a site na mgbanwe dị ukwuu na genotype, na-enye aka na nhụsianya nke ọgba aghara na arụ ọrụ homonụ antidiuretic. Ọnọdụ ebe a ketara eketa bụ n'ihi nkwarụ si n'ọbara diencephalon na agịga.

N'iburu n'uche ihe ndị na - akpata ọrịa insipidus kwesịrị iburu usoro nke mmepe ya:

1) Central insipidus ọrịa shuga - na - apụta na ezughi oke nzuzo nke vasopressin na hypothalamus ma ọ bụ mebie ihe nzuzo ya n'ime ọbara site na ọnya azụ, ikekwe ihe kpatara ya bụ:

Ọmụmụ nke hypothalamus, ebe ọ bụ na ọ bụ ya na-ahazi ịzere mmamịrị na njikọ nke homonụ antidiuretic, mmebi nke ọrụ ya na-ebute ọrịa a. Ọrịa na-efe efe ma ọ bụ nke na-adịghị ala ala: tonsillitis, flu, ọrịa ndị a na-ebute site na mmekọahụ, ụkwara nta nwere ike ịbụ ihe na-akpata ya ma na-akpasu iwe nke ọrịa hypothalamic dysfunctions.
Wa ahụ na ụbụrụ yana ụbụrụ na ụbụrụ.
Okwu mkparịta ụka, mmerụ ahụ ụbụrụ.
Ọrịa autoimmune.
Cystic, degenerative, ọnya ọnya akụrụ na-egbochi echiche banyere vasopressin.
Usoro Tumor nke hypothalamus na pituitary gland.
Ọzọkwa, ọnụnọ nke ọbara mgbali bụ otu n'ime ihe na-aka njọ n'oge ọrịa insipidus ọrịa shuga.
Ọrịa anụ ahụ nke sistem hypothalamic-pituitary, na-eduga na nsogbu nke mgbasa ụbụrụ n'ime arịa ndị na-enye hypothalamus na gland pituitary gland.

2) Insipidus ọrịa shuga ọrịa kansa - ka emepụtara vasopressin na ọnụọgụ nkịtị, agbanyeghị, akụrụ gbasara akụrụ anaghị anabata ya nke ọma. Ihe kpatara ya nwere ike idi otua:

mmebi nke urinary tubules nke nephron ma ọ bụ medulla nke akụrụ,
ihe nketa - ọrịa ọmụmụ,
sickle cell anaemia,
potassium mụbara ma ọ bụ dobe nke calcium ọbara
ụkwara akwara na-adịghị ala ala
amyloidosis (amyloid deposition in tissue) ma ọ bụ polycystosis (nguzobe nke otutu cysts) nke akụrụ,
na-a medicationsụ ọgwụ nwere ike ịbụ nsí na akụrụ ("Demeclocilin", "Amphotericin B", "Lithium"),
mgbe ụfọdụ ihe nlere na - eme n'oge agadi ma ọ bụ na - emegide usoro ọmụmụ ọzọ na - adịghị ike.

Mgbe ụfọdụ, megide ebido nrụgide, akpịrị ịkpọ nkụ (psychogenic polydipsia) nwere ike ime. Ma ọ bụ oria insipidus n'oge afọ ime, nke na-amalite n'ime ọnwa nke atọ n'ihi mbibi nke vasopressin site na enzymes nke Plasenta mepụtara. A na-ewepụ ụdị mmebi a n'onwe ha mgbe ha wepụsịrị ihe kpatara ya.

Nkewa

Ọ bụ ọdịnala ịmata ọdịiche dị n'ụdị ọgwụgwọ 2 nke ọrịa a:

Nehrogenic arịa ọrịa shuga insipidus (mpaghara). Formdị ọrịa a bụ nsonaazụ nke mbelata ma ọ bụ enweghị uche zuru ezu gbasara akwara ndị siri ike na-emetụta vasopressin. Dịka iwu, a na-ahụ nke a n'ihe banyere ọrịa akụrụ na-adịghị ala ala (ya na pyelonephritis ma ọ bụ megide nzụlite ọrịa akụrụ polycystic), mgbatị dị ogologo oge na ọdịnaya potassium na mmụba nke ọkwa calcium, na-enweghị oriri protein zuru ezu na nri - agụụ agụụ protein, ọrịa Sjogren, na ụfọdụ ntụpọ. N'ọnọdụ ụfọdụ, ọrịa ahụ bụ ọdịdị nke okike.
Neurogenic diabetes insipidus (etiti). Ọ na-etolite n'ihi mgbanwe nke nje na akwara ozi, ọkachasị, na hypothalamus ma ọ bụ ọkwa azụ na -akpata. Dịka iwu, ihe kpatara ọrịa ahụ na nke a bụ arụmọrụ iwepu ma ọ bụ akụkụ iwepu ahụ gland, ọrịa na - arịa ọrịa nke mpaghara (hemochromatosis, sarcoidosis), trauma ma ọ bụ mgbanwe na ọdịdị mkpali. N'ụfọdụ oge, ọrịa neurogenic di insipidus bụ idiopathic, na-ekpebisi ike n'otu oge n'ọtụtụ ndị otu ezinụlọ.

Oria oria di insipidus

Njirimara mbụ nke ọrịa insipidus nke ukwuu bụ akpịrị ịkpọ nkụ (polydipsia) na urination na-egbu egbu (polyuria), nke na-enye ndị ọrịa nsogbu n'abalị. Site na ntụtụ 3 (15) nke mmamịrị nwere ike ịpụpụ kwa ụbọchị, mgbe ụfọdụkwa ego ya na-eru lita 20 kwa ụbọchị. Ya mere, akpịrị ịkpọ nkụ na-emekpa onye ọrịa ahụ ahụhụ.

Ihe mgbaàmà nke insipidus ọrịa shuga n’ime ụmụ nwoke bụ mbelata nke ịkwa iko na ikike.
Oria oria di insipidus n’aria nwanyi: nmekpa aru rue amenorrhea, infertility metụtara, ma oburu n’ime ime, enwere ohere ibute ime.
A na-ekwupụta mgbaàmà nke ọrịa shuga n’ime ụmụaka. N'ime ụmụ amụrụ ọhụrụ na ụmụaka, ọnọdụ maka ọrịa a na-adịkarị njọ. A na-achọpụta mmụba nke ahụ ahụ, vomiting na-akọwaghị ya, ọgba aghara nke sistem ụjọ. N’aka umuaka, rue mgbe ha toro, ogbawa n’enweghi oria bu oria, ma obu enuresis.

N'ọdịnihu, n'ọkwa, mgbaàmà ndị a sonyere:

N'ihi oriri nke nnukwu mmiri, afọ na-agbatị, mgbe ụfọdụ ọ ga-ada ọbụna,
Enwere ihe iriba ama nke akpukpo ahihia (enweghi mmiri n’anu ahu): akpukpo ahihia na akpukpo ahihia (onu akpukpo aru), aru ya na - ebelata
N'ihi mgbapụta nke mmamịrị na nnukwu oke, eriri ọkpọ na-agbatị,
N'ihi ụkọ mmiri n'ime ahụ, mmepụta nke enzymes diges na afọ na eriri afọ na-akpaghasị. Yabụ, agụụ onye ọrịa na-ebelata, ọnya afọ ma ọ bụ ọrịa afọ ọsịsa, ọ na-enwe afọ ntachi,
Otutu mgbe obara mgbali ala na olu obi,
Ebe ọ bụ na mmiri ezughị ezu n’ahụ, ọsụsọ na-ebelata,
Ike gwụ onye ọrịa
Mgbe ụfọdụ ọgbụgbọ na ọgbụgbọ na-akọwaghị,
Ahụ nwere ike ịrị elu.
Oge ụfọdụ, ịra akwa (enuresis) na-apụta.

Ebe ọ bụ na akpịrị ịkpọ nkụ na mmamịrị na-aga n’ihu n’abalị, onye ọrịa ahụ na-enwe nsogbu uche na nke mmetụta:

obi ojoo (oge ufodu obuna psyche na ebido) na iwe,
ehighi ura na isi ọwụwa
mgbada ụbụrụ.

Ihe ndia bu ihe ama ama nke oria insipidus n’agha. Agbanyeghị, ngosipụta nke ọrịa ahụ nwere ike ịdị iche na ụmụ nwoke na ụmụ nwanyị yana ụmụaka.

Diagnostics

N'ụdị ndị ọzọ, nchọpụta nke oria insipidus adịghị nhịahụ yana esite na:

akpiri kpọrọ nkụ
olu mmamịrị ụbọchị kwa ụbọchị karịrị 3 lita kwa ụbọchị
plasma hyperosmolality (ihe karịrị 290 mosm / n'arọ, dabere na mmiri ọmụmụ)
akwa sodium
hypoosmolality nke mmamịrị (100-200 mosm / kg)
Nnukwu mmamịrị nke mmamịrị (obere ala)

Iwu nchịkwa

Onye ọ bụla maara na ndị ọrịa na-arịa ọrịa shuga nwere mmekọrịta 'pụrụ iche' na shuga. Ma gịnị ka a ga-ekwu banyere nri na-edozi ahụ ma ọ bụrụ na ọrịa ahụ abụghị shuga? N'okwu a, mmachi ahụ ga-emetụta ngwaahịa ọzọ - nnu. Ọ bụrụ na onye ọrịa anaghị arịa ọrịa gbasara akụrụ, mgbe ahụ ọ ga-ekwe omume iji ihe mgbakwunye nri dochie nnu, dịka ọmụmaatụ, Sanasol.

Nri nwere ọrịa a gụnyere ịmachi nri iri nri protin (karịa karịa 70 g kwa ụbọchị). A na-atụ aro onye ọrịa ahụ ihe nri table 7.

A na-etinye nri na ihe ọ drinksụ drinksụ ndị a na nri:

Tomato na mkpụrụ osisi na-atọ ụtọ.
Inine ọhụrụ.
Ihe ọ juụzedụ eji eghe eghe, kvass, teas - herbal na akwụkwọ ndụ akwụkwọ ndụ.
Mmiri na lemon ihe ọ juiceụ .ụ.
Mmiri ara ehi na ọ andụ drinksụ.
Lean ụdị anụ.
Azụ nwere obere ume, azụ.

Idiopathic insipidus nke ọrịa shuga, enyere ya maka usoro iji dochie anya nke ọma, anaghị enye ndụ onye ọrịa nsogbu, mana iweghachite n'ụdị a agaghị ekwe omume.

Ọrịa shuga adịghị egbu egbu, bụ nke bilitere megide ọrịa nke ọrịa ọ bụla ọzọ, n'ọtụtụ ọnọdụ na-agafe oge na-adịghị anya mgbe ọ wepụsịrị ihe kpatara ya.