Phosphate ọrịa shuga: atụmatụ nke ọrịa ahụ na ụzọ ọgwụgwọ

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Ọrịa shuga na-akpata ọrịa bụ ihe a na-ahụkarị n'ọrịa ndị a na-eketa eketa na-arịa metabolism nke phosphates na vitamin D. Ọrịa hypophosphatemic ọrịa bụ hypophosphatemia, mmịpụta calcium na rickets ma ọ bụ osteomalacia, na-adịghị emetụta vitamin D. Ihe mgbaàmà gụnyere mgbu ọkpụkpụ, mgbaji na ọgba aghara. uto. Nchoputa a dabere na mkpebi nke serum phosphate, alkaline phosphatase na ọkwa 1,25-dihydroxyvitamin D3. Ọgwụgwọ gụnyere nnabata nke phosphates na calcitriol.

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Ihe na - akpata ya na pathogenesis nke ọrịa shuga phosphate

A na - enweta ụdị hypophosphatemic rickets site na ụdị X jikọtara. A na-ejikọ ọnọdụ nke sporadic hypophosphatemic rickets mgbe ụfọdụ na etuto benen mesenchymal (oncogenic rickets).

Ndabere nke oria bu mbelata ihe eji emeghari mmiri n’osimiri proximal, nke n’eduba na hypophosphatemia. Ọrịa a na - etolite n'ihi mgbasa ozi ihe yana ejikọtara ya na nsogbu ndị bụ isi na ọrụ osteoblast. Enwekwara mbelata nke mkpanaka calcium na phosphate. Ọkpụkpụ mejupụtara ọkpụkpụ bụ ihe kachasị n'ihi ọkwa phosphate na dysfunction nke osteoblasts karịa n'ihi ọkwa ọkwa calcium dị ala na ụba nke homonụ parathyroid na rickets na-adịghị ike. Ebe ọ bụ na ọkwa 1,25-dihydroxycholecalciferol (1,25-dihydroxyvitamin D) dị nkịtị ma ọ bụ belata ntakịrị, enwere ike ịmalite ntụpọ na usoro vitamin D dị ike, hypophosphatemia kwesịrị ime ka mmụba nke ọkwa 1,25-dihydroxyvitamin D.

Hypophosphatemic rickets (ọrịa shuga phosphate) na-etolite n'ihi mbelata phosphate reabsorption na proximal tubules. A na-ahụ ọnya ụdọ nke a dịpụrụ iche, ụdị ihe nketa a bụ nke ukwuu, jikọtara ya na X chromosome. Na mgbakwunye, ọrịa shuga phosphate bụ otu n'ime ihe ndị metụtara Fanconi syndrome.

Ọrịa paraneoplastic phosphate na-ebute site na mmepụta nke homonụ parathyroid-dịka nke mkpụrụ ndụ tumo.

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Ọrịa shuga nke Phosphate

Hypophosphatemic rickets gosipụtara onwe ya dị ka usoro nke ọgba aghara, site na hypophosphatemia asymptomatic ruo oge anụ ahụ na-egbu oge na obere ala ruo n'ụlọ ọgwụ nke rickets ma ọ bụ osteomalacia siri ike. Nkpugheputa umuaka na - adi iche mgbe ha bidochara ije, ha na - etolite Ighari-ukwu nke ikpere aka na nrụrụ ọkpụkpụ ndị ọzọ, na - emegharị ụkwụ, mgbu ọkpụkpụ na obere mkpụmkpụ. Otuto uto na saịtị njikọta akwara nwere ike ịkwụsị mmegharị. Site na rickets hypophosphatemic, rickets nke spain ma ọ bụ ọkpụkpụ pelvic, mmerụ enamel ezé na spasmophilia, nke na-etolite na vitamin r-adịghị ụkọ, adịghị ahụkebe.

Ndị ọrịa kwesịrị ikpebi ọkwa nke calcium, phosphates, alkaline phosphatase na 1,25-dihydroxyvitamin D na HPT na ọbara, yana urinary phosphate excretion. Site na rickets hypophosphatemic, ogo phosphates na ọbara ọbara na-ebelata, mana ntụpọ ha na mmamịrị dị elu. Ọkwa calcium na PTH bụ ihe dị mma, alkaline phosphatase na-ebukarị elu. Site na rickets calcium na-adịghị ike, achọpụtala ihu abụọ, enweghị hypophosphatemia ma ọ bụ na ọ dị nro, mwepụ nke phosphates na mmamịrị adịghị abawanye.

Achọpụtala hypophosphatemia n'ime nwa amụrụ ọhụrụ. N'ime afọ 1-2 nke ndụ, akara ngosipụta nke ọrịa ahụ na - ebulite: nlọghachi azụ nke ibu, nrụrụ siri ike nke nsọtụ ala. Akwara isi dị nro ma ọ bụ anọghị ya. Otu aka dị mkpụmkpụ bụ ihe e ji mara ya. N'ime ndị okenye, osteomalacia ji nwayọọ nwayọọ amalite.

Ka ọ dị ugbu a, akọwagola ụdị ọrịa 4 ekerede na hypophosphatemic rickets.

Idị nke m - hypophosphatemia ejikọtara ya - rickets vitamin D na-egbochi (hypophosphatemic tubulopathy, hypophosphatemia ezinụlọ, hepatorial phosphate renal, ọrịa shuga phosphate na-arịa, ọrịa shuga phosphate na-adịgide adịgide, ọrịa akwara renubu tubular rickets, ọrịa Albert Blairt) n'ihi mbelata phosphate reabsorption na proximal renal tubule ma gosipụtara site na hyperphosphaturia, hypophosphatemia na mmepe nke rickets-dị ka mgbanwe ndị na-eguzogide ọgwụ ị na-egbochi vitamin. D.

A na-eche na ya na hypophosphatemic rickets nwere njikọ X, a na-agbaghazi usoro ọrụ 1-a-hydroxylase na phosphate, nke na-egosi ntụpọ na njikọta vitamin D metabolite 1.25 (OH) 2D3. Ntinye uche nke l, 25 (OH) 2D3 n'ime ndị ọrịa belatara nke ọma maka ogo hypophosphatemia dị adị.

Ọrịa ahụ gosipụtara onwe ya ruo afọ 2 nke ndụ. Njirimara kachasị ama:

• uto nke ukwu, squat, ike akwara dị ukwuu, enweghi hypoplasia nke enamel nke ezé na-adịgide adịgide, mana enwere oghere nke oghere pulp, alopecia,
• hypophosphatemia na hyperphosphaturia nwere calcium ọbara nkịtị wee mee ka ọrụ alkaline phosphatase mụbaa,
• nrụrụ ụkwụ siri ike (na mmalite ije),
• Rickets-X-ray mgbanwe dị n’ọkpụkpụ - diaphysis sara mbara nke nwere okpukpu abụọ nke cortical, usoro siri ike nke trabeculae, osteoporosis, nrụrụ vagal nke akụkụ ala, igbu oge n’ọkpụkpụ akpụ, ngụkọta mkpụrụ nke calcium na ọkpụkpụ na-abawanye.

Ntughari ozo nke phosphates n’ime akụrụ na-agbadata ruo 20-30% ma ọ bụ ihe na-erughị, mwepu nke phosphorus na mmamịrị na-abawanye ruo 5 g / ụbọchị, ọrụ nke alkaline phosphatase na-abawanye (ugboro 2-4 ma e jiri ya tụnyere usoro). Hyperaminoaciduria na glucosuria bụ ndị a na-amachaghị. A naghị agbanwe ntụgharị Calcium.

Enwere ụdị ọgwụ 4 na ọgwụ kemịkal dị iche iche nke ọrịa shuga phosphate dị ka mmeghachi omume na ntinye nke vitamin D. Na mgbanwe mbu, mmụba na ọdịnaya nke inorganic phosphates na ọbara n'oge ọgwụgwọ na-esonye na mmụba nke reabsorption ha na tubules renal, na nke abụọ, phosphate reabsorption na akụrụ na eriri afọ na-abawanye, - ịbawanye ụba na-emegharị naanị na eriri afọ, na nke anọ, a na-amụbasi ike na vitamin D, nke mere na ọbụna obere doses nke vitamin D na-akpata ihe ọ signsụ ofụ na-egbu egbu.

IIdị nke II - ụdị hypophosphatemic rickets - bụ ihe na - achịkwa onwe ya, ejikọghị ya na ọrịa chromosome. Ihe eji mara oria a:

• mmalite nke ọrịa mgbe ọ dị afọ 1-2,
• ịkpụ ụkwụ ya na mmalite ije, ma na-enweghị ịgbanwee elu, anụ ahụ siri ike, nrụrụ ọkpụkpụ.
• hypophosphatemia na hyperphosphaturia nwere ọkwa calcium nkịtị yana mmụba na-arụ ọrụ alkaline phosphatase dị ala,
• X-ray: ihe nrịba ama nke rickets, mana osteomalacia siri ike.

Onweghi mgbanwe n’edeputa electrolytes, CBS, nmeghari nke homonụ parathyroid, ihe mejupụtara amino acids ọbara, ọkwa nke creatinine, na nitrogen residual na serum. Mgbanwe mmamịrị bụ ihe anaghị arụ ọrụ.

IIIdị nke III - ịdabere na mmanu nri sitere na vitamin D (agarị agbụrụ, osteomalacia, hypophosphatemic vitamin D-rickets na aminoaciduria). Ihe kpatara ọrịa ahụ bụ imebi usoro nke 1.25 (OH) 2D3 n’ime akụrụ, nke na-eduga n’inwe nrịsị nke calcium na eriri afọ na nsonaazụ vitamin D na-anabata ndị na-anabata ọkpụkpụ, ihu abụọ, hyperaminoaciduria, hyperparathyroidism nke abụọ, ọrịa phosphorus reabsorption na hypophosphatemia.

Mmalite nke ọrịa ahụ na-ezo aka afọ 6 ọnwa. rue afọ abụọ Kachasị mara akara:

• mgbaghara, hypotension, ihe ọdịdọ,
• ihu abụọ, hypophosphatemia, hyperphosphaturia na ụba ọrụ nke alkaline phosphatase n'ime ọbara. Ọ na-abawanye site na hormone plasma parathyroid na-agbatị, a na-ahụkwa aminoaciduria na ntụpọ, mgbe ụfọdụ ntụpọ urinary acidification,
• Ọgwụ mmalite nke ije ije, ịsụ ngọngọ, mmebi ngwa ngwa, akwara ike, enamel hypoplasia, nsogbu ezé,
• X-ray kpughere rickets siri ike na mpaghara etolite ogologo ọdụ ụfụ, ụrọ nke cortical layer, ọchịchọ nke osteoporosis. Enweghị mgbanwe na CBS, ọdịnaya nke nitrogen residual, mana itinye uche nke l, 25 (OH) 2D3 n'ime ọbara na-ebelata nke ọma.

IVdị nke anọ - vitamin D3 - na-eketa n'ụkpụrụ nnwekọrịta akpaaka ma ọ bụ na-eme ya na mberede, ụmụ nwanyị na-arịakarị ọrịa. The mmalite nke ọrịa a chọpụtara na nwata, ya mara:

• akụkụ ụkwụ, nrụrụ ọkpụkpụ, ihe mgbu,
• alopecia ugboro ugboro na oge ụfọdụ mgbe ezighi ike.
• X-ray kpughere rickets nke ogo dị iche iche.

Nchọpụta ọrịa shuga phosphate

Otu n'ime akara eji eche na ọrịa shuga phosphate bụ enweghị ike nke etu vitamin vitamin (2000-5000 IU / ụbọchị) dị na nwatakịrị na-arịa Rickets. Agbanyeghị, okwu ahụ bụ “vitamin Rick-Rickets na-eguzogide ọgwụ vitamin”, nke a na-akpọbubu ọrịa shuga phosphate, ezighi ezi.

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Ọrịa dị iche iche banyere ọrịa shuga phosphate

Ọ dị mkpa iji ọdịiche dị n'ọrịa shuga na-akpata ọrịa shuga na vitamin D, na-enye onwe ya nke ọma na ọgwụgwọ siri ike, ọrịa de Toni-Debre-Fanconi, osteopathy na ọdịda akụrụ.

Mgbe ihe mgbaàmà nke ọrịa shuga phosphate pụtara na nke mbụ okenye, a ga-ewere oncogenic hypophosphatemic osteomalacia. A na-ahụ ụdị mgbanwe a nke ọrịa paraneoplastic n'ọtụtụ etuto ahụ, gụnyere anụ ahụ (ọtụtụ dysplastic nevi).

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Gịnị bụ ọrịa shuga phosphate

Ọrịa shuga Phosphate bụ aha a na-akpọ ọrịa mkpụrụ ndụ ihe nketa, njiri mara ya bụ:

• enweghi ahihia n’arụ,
• mmepe nke ọrịa ọkpụkpụ,
• Ọdịdị mgbaàmà ndị a na-egosipụta rickets.

Ọrịa shuga Phosphate bụ ọrịa na-anaghị ahụkebe nke nwere ohere 1: 20,000 nke ịmalite ya.

A na - amata ihe dị iche iche gbasara ọrịa asatọ na - adabere na mmụpụ nke otu usoro ọmụmụ. Ihe kachasị dị na njikọta hypophosphatemic rickets nke X na-akpata n'ihi mmebi nke usoro REX.

Dabere na nyocha ahụike ọgbara ọhụrụ, ihe nketa mmadụ gụnyere ihe karịrị 28 puku mkpụrụ ndụ ihe nketa.

Ọrịa shuga phosphate bụ ọrịa a na-amụkarị n'ọbara;

Kedu ihe kpatara eji jupụta phosphorus n'ime ahụ n'oge ọrịa?

Mkpụrụ "mkpụrụ ndụ ihe nketa" na-eduga n'ịgba aghara nke ikike nrụpụta phosphorus na ọdụ akụrụ. Ọbara batara na nsị akụrụ ma na-agbazi usoro. N'ihi ya, etolitewo mmamịrị izizi na nke abụọ. Mmalite mbu nwere ihe ndi di nkpa maka ahu: glucose, protein, sodium, phosphorus, calcium. Ihe ndị a bara uru si na akụrụ akwara na-abanye n'ime ọbara. A na-akpọ usoro a 'reabsorption'.

N'ime akụrụ nke akụrụ, ịmụgharị ihe ndị bara uru nye ahụ na-apụta

A na - ewepụ ihe ndị na - adịghị mkpa (toxins, toxins) site na akụrụ ya na mmamịrị nke abụọ: mmamịrị na-abanye ureter, ọnya ma hapụ ahụ n'ahụ site na urethra. Na ọrịa shuga phosphate, a dịghị etinye phosphorus n'ọbara site na akụrụ ya, kama ọ na-ewepụtakwa ya na akwara. A na-emepụta ụkọ nke ihe a n'ime ahụ, nke na-eduga mbibi nke anụ ahụ, atrophy muscle, na ihe gbasara akụrụ, akwara, na ọrịa vaskụla.

Phosphorus bụ ọrụ maka ọnọdụ nke ọkpụkpụ mmadụ, ọ na-emetụtakwa ịrụ ọrụ obi na akụrụ.

Ọrịa metabolism ndị ọzọ na ọrịa shuga phosphate

Ọzọkwa ọrịa ahụ, usoro ndị ọzọ na-adịghị mma na ahụ nwere ike ịhụ ya:

• nsogbu nke homonụ parathyroid (hormone parathyroid), nke na-achịkwa usoro metabolism nke calcium-phosphorus. N'ihi ya, a na-ebelatakwa ọgwụ mgbochi calcium.
• imebi nguzobe na aru nke vitamin D, nke n’arụ n’arụ n’arụ n’arụ ọrụ nke ultraviolet radies, ma banyekwa nri n’arụ. Agbanyeghị, vitamin D nwere ike rụọ ọrụ naanị mgbe usoro dị iche iche nke aputara na tubules gbasara gbasara akụrụ. Site na ọrịa shuga phosphate, a na-akpaghasị usoro ndị a, yabụ ụkọ vitamin D na-apụta n'ime ahụ.

Ihe ịrịba ama nke pathology

Ọrịa ahụ gosipụtara onwe ya na ụmụaka ugbua afọ 1-2 gbagoro na mgbaàmà ndị a:

• obi
• mgbapu nke oghere ihu,
• “Whedị dị ka ụkwụ”

Site na ọrịa shuga phosphate, ụkwụ nwata ahụ na-ewere ọdịdị nke leta “o”

Ọ bụrụ na ọgwụgwọ ahụ amaliteghị na nwata, mgbe ahụ, a na-ahụkarị mgbaàmà ndị ọzọ nke ọrịa shuga phosphate na ndị ọrịa okenye:

• oke mgbu na nkwonkwo nke ala ala, ogwe aka, azụ,
• isi ike nke mmegharị. Ọ na-esiri nwoke ije ije, zachie ụkwụ, gbada ihu,
• ọnya ụkwụ na ogwe aka na-adịkarị ala n'ihi mbibi nke ọkpụkpụ,
• chịngọm chịm
• akụkụ ezé ma ọ bụ ezughị ezu,
• okfu nụ
• nkụda mmụọ na nkụda mmụọ, na-ewere ọnọdụ megide atrophy nke arịa nke spain.

Ojiji ogwu

Na ọrịa shuga phosphate, a na-enye ọgwụ ndị a:

• nkwado phosphorus. A na-anabata nnabata ugboro isii n’ụbọchị. Usoro onunu ogwu g’eji n’onye oria ya ma ndi dibia bekee họrọ ya. Na ọgwụgwọ ụmụaka, ọgwụ nwere ike jikọta ya na ngwakọta mmiri ara ehi, mkpụrụ osisi na akwukwo nri, juices,
• Alfacacidol bụ analogue nke vitamin D. Ọ bụghị naanị ọgwụ a na - eme ka metabolism nke calcium na-egbochi metabolism, kamakwa ọ na - enyere aka belata ihe mgbu, na - eme ka nhazi nke mmegharị dịwanye mma. Usoro ọgwụgwọ na-adabere na ọkwa nke PTH,

Alfacacidol - bụ analog nke vitamin D

Ọgwụ ịwa ahụ

A na-egosi ọgwụgwọ ịwa ahụ maka ọrịa shuga phosphate n'ọnọdụ ndị dị otú a:

• nwere ogologo ụkwụ dị iche. Ihe a na - eme na mgbe otu aka na - agbadata akwa mgbanwe karịa nke ọzọ,
• ya na mgbanwe di omimi banyere usoro ikpere, ukwu na nkwonkwo ụkwụ. Ọrịa ndị dị otú a na-etolite etolite na ịbụ okenye na ọrịa shuga phosphate dị elu. Mgbanwe nke nkwonkwo anaghị ekwe mmadụ ịga ebe ọ bụla ọ nwere ike bute nkwarụ.

Ofdị ọgwụgwọ ogwugwo:

• nwa oge epiphysiodesis. A na-eme ya ogologo ogologo ụkwụ dị iche iche maka ụmụaka gbara afọ 15. N'oge a, mmadụ nọ n'oge uto, yabụ site na enyemaka nke ngwaọrụ ahụike, ị nwere ike idozi mmụba ogologo nke aka. N'elu ụkwụ, nke kwesiri ka ọ dị mkpụmkpụ, a na-etinye efere dị 8. Ngwaọrụ ndị ahụ nwere aka ekpe n’elu yana n’okpuru mpaghara uto ahụ. Mpaghara akụkụ ahụ pupụtara n'apata ụkwụ na-adị n'apata ukwu na ala, yana kwa na ala ala ụkwụ,
• osteotomy na-agbazi. N’oge ịwa ahụ, ọkpụkpụ nwere mmerụ ahụ na-agbaji. Ọzọ, nkwonkwo ahụ nyere udi nke ziri ezi, nke edobere na efere na kposara,
• nnọchi nkwonkwo. N'oge ịwa ahụ, a na-eme obere mbepụ n'akụkụ nke njikọ nkwonkwo metụtara. Nkwonkwo nwere nkwarụ na-anọchi anya site na prosthesis, ọnya ahụ na-egbu oyi.

Ọ bụrụ na onye ọrịa nwere nkwonkwo ikpere ikpere na-akụ afọ n’ala dara ada, mgbe ahụ ọ ga-edochi ya site na prosthesis

Etu esi ezere oria onu

Ndị ọrịa nwere ọrịa shuga phosphate nwere ohere dị elu nke ibute ọrịa nje. Iji zere imebi ezé na goms, iwu ndị a ga-agbaso:

• ehicha ezé gị ugboro abụọ n’ụbọchị. N'okwu a, jiri brusles dị nro,
• mgbe ị risịrị nri ọ bụla, were ọgwụ mgbochi gwọchie ọnya ọnụ.
• zere iji swiiti (Grafica, sugar, achịcha, marmalade),
• gaa na dọkịta ezumike ọ dịkarịa ala 1 oge kwa ọnwa,
• kpuchie elu nke ezé site na iji mkpuchi plọgel pụrụ iche na enamel. Usoro mgbochi dị otú a na-arụ n'ụlọ ọrụ eze ọ bụla.

Ọrịa shuga phosphate n'ime ụmụaka: ihe kpatara, mgbaàmà, ụkpụrụ ọgwụgwọ

Okwu ahụ bụ "ọrịa shuga phosphate" na-ejikọkọta otu ọrịa ọrịa ihe nketa dị ka ọrịa, nke gbakwasara ụkwụ nke phosphates na proximal tubules nke nephron, nnabata ha na eriri afọ ma, n'ihi ya, ụkọ nke salts acid acid dị n'ahụ ahụ. Enwekwara aha ozo maka ogwu a. N'ihi ogo dị ala nke ngwakọta phosphorus na ọbara na foto ụlọ ọgwụ nke rickets, a na-akpọkwa ya hypophosphatemic rickets, ma na-eburu n'uche ịdị ala nke ọgwụgwọ na vitamin D, a na-akpọ ya rickets vitamin D na-eguzogide.

Usoro ogwu a bụ nsogbu a na-ahụkarị n'ọrịa ụmụaka orthopedics na nephrology. Ọdịmma ya bụ n'ihi mkpa ọ dị ogologo oge, mgbe ụfọdụ ọgwụgwọ oge ndụ, enweghị ike nke usoro ọgwụgwọ ugbu a iji kpochapụ ngosipụta ụlọ nke ọrịa na nrụrụ ọkpụkpụ.

Nkọwa mbụ nke ọrịa pụtara na narị afọ nke 20. Edebara onye ọrịa ahụ na ụdị dịgasị iche iche nke hypophosphatemic rickets yana ọrụ nke ketara eketa gosipụtara ya. Mgbe emesiri, achoputara oria ndi ozo nke bu oria phosphate, nke nwere njiri mara ha na ihe ha na-akpata, udiri ihe nketa na ihe ndi ozo. N'okpuru ebe anyị bi na isi ihe.

Ọmụmụ ịrịa ọrịa shuga phosphate bụ polymorphic. Ọrịa ahụ na-eme ka ọmarịcha ya na nwata, mana ọ nwere ike igosipụta onwe ya ma emesịa - na afọ 7-9. Ọzọkwa, ogo nke mgbaàmà ọrịa nwekwara ike ịdị iche. N'ọnọdụ ụfọdụ, ọrịa ahụ nwere usoro asymptomatic ma gosipụta ya site na mgbanwe dị nro na metabolism phosphorus-calcium. Agbanyeghị, ụdị hypophosphatemic rickets na-enwekarị ihe osise a na-ahụkarị:

• mmezu nke mmepe ahu na uto ya,
• nkwarụ nke ọkpụkpụ aka (nrụrụ ọkpụkpụ) nke ọgịrịga ala, mgbatị ọkpụkpụ nke aka ya, mbibi nke okpo ụkwụ).
• mgbanwe na uru nwa ahụ (yiri duck)
• imebi nguzobe ezé,
• ọrịa ọnya
• ihe mgbu, wdg.

Akwara hypotension, njiri mara ezi rickets, anaghị adịkarị n'ọrịa shuga phosphate.

Mmepe ọgụgụ isi nke ọrịa a anaghị ata ahụhụ.

Nchọpụta ọrịa shuga phosphate dị na ụmụaka sitere na onyonyo a na-ahụkarị, data sitere na nyocha anụ ahụ na nyocha. Achọpụtara nchọpụta ahụ site na nsonaazụ ụlọ nyocha na ngwa ọrụ:

• mgbanwe na nnwale ọbara (hypophosphatemia, alkaline phosphatase mụbara, ọkwa nkịtị ma ọ bụ elu nke homonụ parathyroid na calcitonin) yana mmamịrị (hyperphosphaturia, wedata phosphate mbelata na mkpịsị akụrụ, ịmụba calcium naanị na hypophosphatemic rickets with calcuria),
• X-ray data (ihe ịrịba ama nke osteoporosis system, nrụrụ ọkpụkpụ, mgbanwe nke ọkpụkpụ), osteomalacia).

Mgbe ụfọdụ ọrịa ahụ malitere, a na-achọpụta ndị ọrịa dị otú ahụ na rickets, a na-atụkwa ọgwụ na vitamin D, ụdị ọgwụgwọ ahụ anaghị arụpụta ma na-enye ihe mere ha ga-eji chee na ọrịa shuga phosphate dị na nwatakịrị. Ọ bụrụ na ọ dị mkpa, n'ọnọdụ ndị dị otú a, enwere ike ikenye ọmụmụ mkpụrụ ndụ ihe nketa iji mata mmebi mkpụrụ ndụ ihe nketa.

A na - ahụta njikọta nke hypophosphatemia na rickets nke aka n'ụfọdụ ọnọdụ ọrịa ndị ọzọ ga - eme nchọpụta ọdịiche:

• Ọria akụrụ (akụrụ akwara tubular acidosis, ọrịa akụrụ na-adịghị ala ala) na imeju (cirrhosis),
• pathology endocrine (hyperfunction nke glands parathyroid),
• ịba n'ahụ akwara, ọrịa celiac enteropathy,
• alimentary (nri) ụkọ nke vitamin D na site,
• ị certainụ ọgwụ ụfọdụ.

Ọgwụ zuru oke nke hypophosphatemic rickets kwesịrị ịmalite na mmalite nke ọrịa ahụ. Nke mbu, ebum n’uche ya banyere mmezi nke nsogbu nke ihe omimi na mgbochi nke mmebi ọkpụkpụ. Mgbe edeputara ya, a na-echebara ọrụ nke usoro a na ntinye nke onwe ndị ọgwụ anya.

Ndabere nke ọgwụgwọ ọgwụgwọ bụ ọgwụ ogologo oge na oke ọnụọgụ vitamin D. A na-enye ya iwu:

• jiri rickets na-arụ ọrụ n'ime anụ ahụ,
• ụfụ nke ọgwụ na mmamịrị,
• mụbara alkaline phosphatase n’ime ọbara,
• na nkwadebe maka ịwa ahụ iji dozie nrụrụ ọkpụkpụ.

Nri mbụ nke vitamin D bụ 10,000-20000 IU kwa ụbọchị. A na-emewanye mmụba ha n'okpuru nchịkwa ndị na-egosi metabolism nke-calcium metabolism n’ime ọbara. Oke onunu ogwu nke ubochi nwere ike idi elu ma gha ufodu ruru 250,000-300,000 IU.

Na ọnụnọ nke ekweghị mmadụ nọrọ na vitamin D, yana nnukwu ịba ụba, a na-ele ịhọpụta ụdị ọgwụgwọ ahụ adịghị mma.

Na mgbakwunye na vitamin D, a na-atụ aro ka ndị ọrịa dị otú a:

• phosphorus na nhazi nke calcium,
• ngwakọta nke citrate (n'ime ọnwa isii iji meziwanye nnabata ndị a na - achọpụta).
• homonụ na-eto.

N'ime oge dị ukwuu nke usoro ahụ, a na-adụ ndị ọrịa ọdụ ka ha hie ụra, mgbe ha nwesịrị mgbaghara - ọgwụgwọ ịhịa aka n'ahụ, mmega ahụ a na-eme na spa spa.

Ihe nlebara anya maka odi nma na nti ajuju bu:

• ọdịmma,
• osooso nke uto,
• nkịtị usoro nke site na metabolism nke phosphorus n'ime ahụ,
• ezigbo rediological radio (weghachite usoro ọkpụkpụ).

Ọnụnọ nrụrụ ọkpụkpụ na –emebi ndabere nke mgbatị ahụike na ụlọ nyocha ugboro ugboro, a na-eme mgbazi ha. Enwere ike iji usoro ndị a maka nke a:

• osteotomi (dissection) nke ogologo ọkpụkpụ toubu na ndọtị nke eriri aka ya,
• mgbochi nke Ilizarov ndọpụ uche na ngwa mkpakọ.

Ekwesịrị ịrụ ụdị ọrụ ahụ naanị mgbe ọgwụgwọ ogologo oge na nyocha nke ogologo oge gasịrị.

Ọ bụrụ na a na-enyo enyo ọrịa shuga phosphate, ọ dị mkpa ịkpọtụrụ dọkịta na-ahụ maka ụmụaka, mgbe nyocha nke mbụ, ga-eduga nwatakịrị ahụ maka ịgakwuru onye ọrịa endocrinologist, orthopedist, na nephrologist. Ọgwụgwọ a gụnyere masseur, physiotherapist, ọkachamara na usoro mmega ahụ na usoro ọgwụgwọ. Ọ bụrụ na ọ dị mkpa, dọkịta na-awa ahụ ga-awa ahụ.

N'ịchọpụta ọgwụgwọ n'oge yana ọgwụgwọ n'oge, prognosis maka ọrịa shuga phosphate dị mma. Agbanyeghị, ụfọdụ ndị ọrịa chọrọ ọgwụ ogologo oge na vitamin D. Ọrịa ịchọpụta na-ekpebi ịkọ nkọ ka njọ, ebe nrụrụ ọkpụkpụ na-ebelata ịdị mma nke ndị ọrịa.

Ọrịa shuga phosphate na ụmụaka: otu ọrịa si egosipụta onwe ya, ọgwụgwọ na foto

Esemokwu nke ọrịa shuga phosphate adịghị emetụta mmebi nke pancreas na mmụba nke glucose ọbara.

Ọrịa a, dị ka ọrịa shuga, nwere mgbochi ọrịa. Ngosiputa ya bu n’ihi eziokwu a na-eme ka a ghara iji mmiri eme ihe n’ime obara.

N’ime ọbara, itinye uche ya na-agbada, ihe mebiri emebi anụ ahụ bụ nke na-eduga n’inwe mmebi nke akwara na mgbakasị ahụ.

Dabere na ihe kpatara phosphate, ọrịa shuga nwere ike ikpebi site n’ọmụmụ ma bufee ya n’aka ndị nne na nna na-arịa ọrịa ma ọ bụ bụrụ ngosipụta nke etuto ahụ (oncogenic rickets).

Hypophosphatemic rickets na-adị na mbelata phosphorus site na mmamịrị mbụ ya, yana nsị nke calcium na phosphat na-emetụta site na eriri afọ, mbelata na mkpokọta vitamin D yana mmegharị ya na imeju. Mbelata na ọrụ nke mkpụrụ ndụ na - akpụpụta akwara ọkpụkpụ (osteoblasts) na - eduga n'eziokwu ahụ na ọkpụkpụ nwere usoro na - akpata ọgba aghara.

Aremụaka na-arịa ọrịa na ọnụnọ nke otu ọrịa na nne na nna ha. Enweghị ụzọ ọ bụla akọwapụtara maka igbochi ọrịa ahụ. Ọ bụrụ na nna ahụ na-arịa ọrịa, ọ na-enyefe nwa ya nwanyị ọrịa phosphate, ụmụ nwoke na ụmụ ndị nwanyị nwere ụdị mmepe ahụ nwere ike ịmụ nne site na nne na-arịa ọrịa. A na-ejikọ ihe ọmụmụ sitere na ọrụ nke osteoblasts na ọdịnaya phosphorus n'ime ọbara na chromosome X.

Nke kachasị njọ, ụmụ nwoke na-ata ahụhụ site na hypophosphatemic rickets. N’oge agadi, ọrịa ahụ nwere ike jikọta ya na akpụ n’ime ọkpụkpụ ma ọ bụ anụ ahụ dị nro.

Na ọrịa shuga phosphate, nsogbu ndị dị otú ahụ malitere:

1. Ọkpụkpụ
2. Ikwu dị nro
3. Mgbanwe nke nkwonkwo ụkwụ na ikpere
4. Ọkpụkpụ mkpụkpụ ụkwụ aka.

Hypophosphatemic rickets nwere ike ịmalite mgbe ọ bụ nwata, ọ na-abụkarị mgbe nwa ahụ bidoro ije ije n'adabereghị. Tupu nke a, ọnọdụ izugbe nwere ike ịnọgide na-adị ọfụma ma ghara ibute ndị dọkịta na-enyo enyo.

Ihe ịrịba ama nke mbụ bụ nwatakịrị ahụ achọrọ, yabụ imetọ ya n’ọkpụkpụ mgbe ọ na-eje ije. Maymụaka nwere ike jụ ịgagharị n'enweghị enyemaka. N’ọdị n’ihu, ụkwụ na-echilata na usoro nke ikpere na nkwonkwo nkwonkwo na-ama jijiji, ọkpụkpụ na mpaghara aka

Ihe ngosi ndị dị otú a jikọtara ya bụ mmebi nke iguzosi ike n'ezi ihe nke enamel nha nzụlite na otutu nke nnabata, oke ọkpụkpụ na ọkpụkpụ pelvic.

Ihe ozo bu njiri mara nke ọrịa mamiri Fofat bu:

• Uda olu adalatala.
• Spasmophilia.
• Ọkpụkpụ n’ụdị n’ụkwụ.
• Ọkpụkpụ na-emebi emebi na nrụrụ ọkpụkpụ.
• Eningkpụpụ ụkwụ nke aka, oge anaghị agbasa

Nnyocha x-ray kpughere diaphisation buru ibu (akụkụ nke ọkpụkpụ tubular), njupụta nke ọkpụkpụ, osteoporosis, ịkpụkpụ ọkpụkpụ, ọkpụkpụ nwere oke calcium.

Otu njiri mara ọrịa a na-achọpụta bụ enweghị nzaghachi na ịsesụ ọgwụ vitamin D, n'adịghị ka ọrịa rickets, yana ọrịa phosphate, ojiji a anaghị ebelata ihe mgbaàmà nke ọrịa.

Ọzọkwa, mgbe ị na-eme nchọpụta, nchọpụta nke phosphates na mmamịrị dị ọtụtụ oge karịa ụkpụrụ nkịtị.

Nyocha ọbara na-ekpughe ihe ndị dị n’ime foshorus dị ala. Iji wepu ọrịa nke ọrịa parathyroid gland, a na-enyocha ọkwa nke homonụ parathyroid. Site na ọrịa shuga phosphate, ọ na-adị elu ma ọ bụ na-enweghị oke. Ihe onyonyo gosiputara homonụ parathyroid na-egosiputa mbelata nke akwara gbasara akụrụ.

Na mgbakwunye, na ndị ọrịa, enwere ike ịchọpụta ọrụ alkaline phosphatase mgbe ụfọdụ na obere calcium n'ọbara ma ọ bụrụ na edepụtara ọrịị nke phosphorus dị elu.

A na-eji salts phosphoric acid nke calcium na sodium na-agwọ ọrịa shuga na ụmụaka na kilogram 10 nke phosphate kwa 1 n'arọ nke ahụ́ nwatakịrị ahụ ugboro 4 kwa ụbọchị. A na-ewere ọgwụ ọjọọ n'ụdị edozi ma ọ bụ mbadamba.

Iji gbochie mmebi nke metabolism metabolism, a na-enye vitamin D .. A na-eji ya amalite site na usoro nke 0.005 μg ma na-abawanye 0.03 μg kwa 1 kilogram nke ahụ. N'otu oge ahụ, ọkwa nke phosphorus n'ime ọbara na-ebili, ọrụ nke alkaline phosphatase na-ebelata.

Iji gbochie itinye salts nnu n'ụdị okwute, akwara a na-achịkwa ọkwa dị na ọbara na mmamịrị. Site na iji ụkpụrụ nkịtị, ị nwere ike jiri nwayọ mee ka ọnụọgụ vitamin D dịkwuo elu.

Ọzọkwa, a na-egosi ndị ọrịa dị otú a ahazi nke nhazi calcium. Iji melite ntopute nke salts nke site na calcium si na eriri afọ lumen ha na-agwakọta na citric acid. Tinye Calcium Gluconate, Fitin, Calcium Glycerophosphate, Sodium Citrate. A na-eme ọgwụgwọ ahụ ogologo oge - ọnwa isii.

Na mgbakwunye, usoro ọgwụgwọ ndị a ka enyere ndị ọrịa:

1. Ọgwụ Vitamin na tocopherol (vitamin E) na vitamin A.
2. Nhọrọ nke ogwugwu nke akwara orthopedic maka idozi curvature nke spain.
3. Na ngwụsị nke uto, a pụrụ ịmalite ime ọgwụgwọ nke ọkpụkpụ na-eme ka ọkpụkpụ ọgwụgwọ dị ukwuu.
4. Site na ọrịa shuga oncogenic foseti, a na-ewepụ etuto ahụ.

N'ime usoro ọrịa a nwere oke mgbu na ọkpụkpụ, spain na nkwonkwo, a na-enye ndị ọrịa ọgwụ ezumike. Ọ na-abụkarị ụbọchị iri na ise. A na-atụ aro iji ọgwụ ndị na-egbu mgbu na ọgwụ mgbochi mbufụt.

Mgbe ọrịa ahụ gaferela nkwụsi ike nke ụlọ ọgwụ na mgbatị ahụ, a na-enye ndị ọrịa iwu ka ọ na -emega ahụike yana mmachi nke ịwụ elu na mmega ahụ siri ike.

A na-atụ aro ka ọ na-eduzi usoro ịhịa aka n'ahụ, ịsa ahụ nnu na-agagharị na mmiri ikuku, ọgwụgwọ na ọnọdụ sanatorium.

A na - amata ụdị ọrịa anọ dabere n'ụdị nsogbu metabolic. Abụọ na ọdịiche abụọ nke ọrịa ahụ dị mma (gbasara ịkọ ogologo oge). Nhọrọ nke mbu bidoro n’afọ mbụ nke ndụ, obere nrụrụ ọkpụkpụ, a na-anabata vitamin D nke ọma. E jikọtara ya na mkpịsị nke phosphorus na calcium yana mmamịrị na feces.

N’ime mgbanwe nke abụọ, ọrịa ahụ bidoro n’afọ nke abụọ nke ndụ, akpọpụtara mgbanwe mgbanwe ọkpụkpụ, a na-ebelata phosphorus n’ime mmamịrị. Vitamin D na-egosi nguzogide. A na-enwekarị ọgwụ phosphorus ebe ọ bụ na mmebi akụrụ mere na ọrịa mellitus. A na-ebelata uto nke ụmụaka, ahụrụ ahụ siri ike. Ihe ngosi X-ray nke rickets, nro n’ọkpụkpụ.

Nhọrọ nke atọ na-amalite mgbe ọ dị afọ ise, ọkpụkpụ na-emebi emebi nke ukwuu, a na-ebelata kalsel dị n’ọbara, a na-etinyekwa calcium na phosphates n’ime eriri afọ. Vitamin D gosipụtara nguzogide.

Aremụaka na-echefu echefu, ezé nwere ntụpọ na enamel, na-enwekarị nsogbu. A na-agbadata ọkwa nke kalsia ọbara, a na-ahụkwa ọtụtụ amino acid na mmamịrị. E nwere ihe iriba ama nke hyperfunction nke abụọ nke gall parathyroid. Nyocha x-ray na-ekpughe mgbanwe n’akụkụ uto ọkpụkpụ, osteoporosis.

Ejiri nhọrọ nke anọ mara nsiwanye ike na vitamin D na ebumnuche nke hypervitaminosis, ọbụlagodi mgbe e jiri ya mee obere ọgwụ. Site na mgbe nwata bụ, etinyere mbọ ụkwụ, isi nkwọcha na mmebi ezé.

Ihe ojoo nke oria phosphate gụnyere:

• Mmebi nke postcho na deformation nke ala nsọtụ.
• Nkịtị ma ọ bụ oge mgbagha echiche.
• Ọkpụkpụ na ezé etolite etolite.
• Calcium na akụrụ.
• Ihe isi ike na nnyefe (a chọrọ ngalaba caesarean).

Mgbochi oria a na-eme na nyocha nke mkpụrụ ndụ ihe dị na nhazi nke ịtụrụ ime, ọkachasị ma ọ bụrụ na enwere ụdị ikpe ahụ dịka agbụrụ dị n’ime ezinaụlọ ma ọ bụ ndị ikwu. Ebe a na - enye ndị mmadụ ọrịa mkpụrụ ndụ ihe nketa nwere ike ibute nsogbu nke ikesa ọrịa shuga phosphate.

Ọ bụrụ na nwatakịrị ahụ nọ n'ihe ize ndụ, mgbe ahụ, a na-enyocha ya site na ịmụ nwa, na-enyocha ọkwa nke phosphorus na calcium n'ọbara na mmamịrị, ma na-enyocha usoro nke ọkpụkpụ, na-agbaso ụkpụrụ nke afọ, nyochaa mmeghachi omume na ịnweta ọgwụ vitamin D. Na ọnụnọ nke ihe ịrịba ama mbụ nke ọrịa ahụ, a na-enye ụmụaka iwu. ọgwụ vitamin. Ndị nne na nna kwesịkwara itinye akwụkwọ maka uru maka nwatakịrị nwere ọrịa mellitus ma nata ọgwụ na njem n'efu na ebe nlekọta ahụike.

Na vidiyo dị n'isiokwu a, Dr. Komarovsky na-ekwu maka ụkọ vitamin D.

Phosphate ọrịa shuga: atụmatụ nke ọrịa ahụ na ụzọ ọgwụgwọ

Ọrịa shuga phosphate bụ ọrịa e ketara eketa na-enweghị ihe jikọrọ ya na ọrịa shuga. A malitere usoro ọmụmụ n'ihi ọrịa metabolic na ahụ na ahụ ya gosipụtara onwe ya na nwata. Iji chọpụta ihe ịrịba ama mbụ nke ọrịa n'oge na-amalite ime ihe nke ọma, ọ dị mkpa inwe echiche nke mgbaàmà nke ọrịa shuga phosphate, yana ụzọ nchọpụta na ọgwụgwọ.

Ọrịa shuga Phosphate bụ aha a na-akpọ ọrịa mkpụrụ ndụ ihe nketa, njiri mara ya bụ:

• enweghi ahihia n’arụ,
• mmepe nke ọrịa ọkpụkpụ,
• Ọdịdị mgbaàmà ndị a na-egosipụta rickets.

Ọrịa shuga Phosphate bụ ọrịa na-anaghị ahụkebe nke nwere ohere 1: 20,000 nke ịmalite ya.

A na - amata ihe dị iche iche gbasara ọrịa asatọ na - adabere na mmụpụ nke otu usoro ọmụmụ. Ihe kachasị dị na njikọta hypophosphatemic rickets nke X na-akpata n'ihi mmebi nke usoro REX.

Dabere na nyocha ahụike ọgbara ọhụrụ, ihe nketa mmadụ gụnyere ihe karịrị 28 puku mkpụrụ ndụ ihe nketa.

Ọrịa shuga phosphate bụ ọrịa a na-amụkarị n'ọbara;

Gịnị bụ ọrịa a?

Ọrịa shuga Phosphate bụ aha a na-akpọ ọrịa mkpụrụ ndụ ihe nketa, njiri mara ya bụ:

• enweghi ahihia n’arụ,
• mmepe nke ọrịa ọkpụkpụ,
• Ọdịdị mgbaàmà ndị a na-egosipụta rickets.

Ọrịa shuga Phosphate bụ usoro ọmụmụ nke na - esiteghị na imebi insulin na pancreas na oke glucose dị n'ọbara. Ihe kpatara ọrịa a bụ metabolism nke vitamin D, yana phosphates. Site na nchọpụta nke ọrịa shuga phosphate, a dịghị ewepu ihe ndị a na tubules akụrụ, a na-ejikwa usoro kemịkal na-ezighi ezi mara njiri anụ ahụ.

A na-ahụta ka ọ bụrụ mmebi a na-ahụkarị, ihe gbasara nke puru omume mmepe nke 1: 20,000. Esemokwu nke ọrịa shuga phosphate adịghị emetụta mmebi nke pancreas na mmụba nke glucose ọbara. Ọrịa a, dị ka ọrịa shuga, nwere mgbochi ọrịa. Ngosiputa ya bu n’ihi eziokwu a na-eme ka a ghara iji mmiri eme ihe n’ime obara. N’ime ọbara, itinye uche ya na-agbada, ihe mebiri emebi anụ ahụ bụ nke na-eduga n’inwe mmebi nke akwara na mgbakasị ahụ.

• N25.1 Ọrịa shuga na-arịa ọrịa kansa ọbara
• N25.8 Nsogbu ndi ozo n'ihi akwara gbasara akwara

Isi ihe kpatara ya na pathogenesis

Ihe bu oria a bu site na reabsorption (nke ozo iwegharia) nke phosphates n’ime mkpo akwara proximal, nke n’eduba n’ibelata ogo ha n’ahu. Ihe a merenụ bụ ihe metụtara ime arụ na - arụ ọrụ nke mkpụrụ ndụ ọkpụkpụ. N’ihi ya, a na-ebelata udu mmiri nke phosphates, calcium na vitamin D.

Ọrịa a bụ nsonaazụ nke mmụba na X chromosome, nke na-akpaghasị nnabata nke phosphates na akụrụ renal, ma emesịa bido usoro nke usoro na - egbochi mkpụkọ nkịtị nke kalsel site na anụ ahụ.

• Menmụ nwoke ndị na-ebugharị usoro nkwarụ ahụ na-ebunye ụmụ ha ndị ọrịa.
• Womenmụ nwanyị ndị na-ebugharị usoro mmerụ ahụ na-ebute ụmụaka nke nwoke na nwanyị (na ụmụ ndị nwoke na ụmụ ndị nwanyị) ọrịa ahụ.
• Nke kachasị njọ, ụmụ nwoke na-ata ahụhụ site na hypophosphatemic rickets. N’oge agadi, ọrịa ahụ nwere ike jikọta ya na akpụ n’ime ọkpụkpụ ma ọ bụ anụ ahụ dị nro.

Nkewa

N'ime ọgwụ ọgbara ọhụrụ, a na-ahụta ụdị ọrịa 5 dị iche iche, dabere na mkpụrụ ndụ ihe nketa enwerela mmụba.

1. Typedị jikọtara X bụ ụdị ọrịa a na - ahụkarị ọrịa phosphates n'ime mmamịrị, na - eguzogide vitamin D. Pathology gosipụtara onwe ya n'ime afọ abụọ mbụ nke ndụ nwatakịrị. Guo gbasara akwukwo nri vitamin D-Resistant Rickets
2. Osdị akwara autosomal - ọrịa a dị ụkọ, a na-aghọta ya nke ọma, na - apụta n'ihi mmụba na usoro ihe omumu, nke bụ maka ebilite dentin nkịtị, anụ ahụ.
3. Dị nfụkasị X - ejikọtara ọnụ site na mkpụrụ ndụ ihe mebiri emebi bụ ụmụ nwanyị, mana ọrịa ahụ na-etolite na ụmụ nwoke. A na-ahụ maka ọrịa ụbụrụ site na ọgba aghara cha cha nke phosphate ion site na epithelium nke nephrons.
4. Osdị Autosomal - ka a na-ahụ anya n'ụdị ọrịa na - eme nwayọ, nke a na-ahụ site na ịba ụba nke phosphate ion na mmamịrị, hypophosphatemia.
5. Dị nnweghachi akpaaka na hypercalciuria bụ ụdị ọrịa na-adịghị ahụkebe. Na mmamịrị, ọdịnaya nke phosphorus na calcium na-abawanye, na plasma ọbara ọkwa ọkwa nke ihe ndị a na-ebelata.

Dị Mkpa! Ọrịa shuga Phosphate bụ ọrịa ọgbụgba. Mpempe enwetara na ndị okenye ka achọpụtara na ọnụnọ ụfọdụ neoplasms dị omimi na ọkpụkpụ na anụ ahụ dị nro, a na-akpọ oncogenic rickets.

Ihe ịrịba ama nke mbụ na ụmụaka

Kedu ka esi gosipụta ọrịa shuga phosphate n'ime ụmụaka?

• Enwere nlọghachi azụ na-eto.
• Twkwụ gbagọrọ agbagọ.
• Nkwonkwo ikpere na nkwonkwo ụkwụ na-emebi emebi.
• Ọkpụkpụ dị na mpaghara nke nkwonkwo aka aka.
• Uda olu.
• N'oge palpalica, a na-enwe mgbu azụ na ọkpụkpụ. Ọkpụkpụ siri ike nwere ike ime ka nwatakịrị kwụsị ịgagharị onwe ya n'ụkwụ ya.
• N'ọnọdụ ndị na-adịghị ahụkebe, ntụpọ enamel na ezé, rickets na spain ma ọ bụ ọkpụkpụ pelvic na-ahụ.
• Spasmophilia, njiri mara rickets nwere ụkọ vitamin D, nwere ike ịmalite.
• Ọ nwere ike ga - aka mbọ ụkwụ aka nwa amụrụ ọhụrụ (a na -echekarị ya).
• Na ọgbọ, onye ọrịa na-etolite osteomalacia.
• Ihe onyonyo X-ray na egosiputa osteoporosis, a na –ezube ọkpụkpụ n’aho.
• Calcium dị elu n’ọkpụkpụ.
• Ngwakọta nke electrolytes, amino acids ọbara, creatinine, CBS agbanweghị.

Nwatakịrị choro otutu ihe bara uru ma na-edozi ahụ, gụnyere phosphorus na calcium, maka mmepe na uto nkịtị. Enweghị ihe ndị a na-eme n'afọ mbụ nke ndụ na-akọwa ịdị njọ nke ọrịa ahụ.

Mgbaàmà nke Ọrịa Shuga Phosphate

Ngosiputa oria phosphate n'ihi ihe agha sitere na nkpuru nke oria a bu ihe ndi n’aru oke ibu - site na nrutari asymptomatic n’aru nsogbu ojoo. Enwere ike igosipụta ụfọdụ ihe gbasara ọrịa (dịka ọmụmaatụ, n'ihi mmụba na mkpụrụ ndụ FGF23) naanị site na hypophosphatemia na mmụba nke ọkwa phosphorus na mmamịrị, ebe enweghị mgbaàmà ọria. Agbanyeghị, ọtụtụ mgbe, ọrịa shuga phosphate na-eduga na foto nke rickets na-ahụkarị ma na-etolite na nwata - 1-2 afọ, n'oge na-adịghị anya nwa ahụ malitere ije ije.

Ọmụmụ ịrịa ọrịa shuga phosphate bụ polymorphic. Ọrịa ahụ na-eme ka ọmarịcha ya na nwata, mana ọ nwere ike igosipụta onwe ya ma emesịa - na afọ 7-9. Ọzọkwa, ogo nke mgbaàmà ọrịa nwekwara ike ịdị iche. N'ọnọdụ ụfọdụ, ọrịa ahụ nwere usoro asymptomatic ma gosipụta ya site na mgbanwe dị nro na metabolism phosphorus-calcium.

Ihe ịrịba ama nke mbụ bụ nwatakịrị ahụ achọrọ, yabụ imetọ ya n’ọkpụkpụ mgbe ọ na-eje ije. Maymụaka nwere ike jụ ịgagharị n'enweghị enyemaka. N’ọdị n’ihu, ụkwụ na-echilata na usoro nke ikpere na nkwonkwo nkwonkwo na-ama jijiji, ọkpụkpụ na mpaghara aka

Ihe ngosi ndị dị otú a jikọtara ya bụ mmebi nke iguzosi ike n'ezi ihe nke enamel nha nzụlite na otutu nke nnabata, oke ọkpụkpụ na ọkpụkpụ pelvic.

Ọrịa ndị na-egosi na nsogbu nke ahụike na-ebute uto nke ọrịa shuga phosphate bụ ndị a:

• Akpukpo ahu di na onodu nwata ahu.
• Igha azu uto.
• Curvature nke akụkụ ala dị n'ụdị okirikiri.
• Mgbanwe nke nkwonkwo ụkwụ ma ọ bụ ikpere.
• Muscleda olu olu.
• Na azụ, mgbe palpating, ihe mgbu na-apụta.
• Inggbanwe oghere nwa ahụ (yiri dock)
• Imebi nke ezé,
• Ọrịa akwara na-akụrisị,
• Ọkpụkpụ mgbu, wdg.

Ọmụmụ ihe gbasara ahụ na-akọwa isi ihe na-arịa oria ahụ bụ na mmadụ nwere nsogbu na nrụpụta nke akwara ọkpụkpụ yana nrụrụ nke akụkụ ahụ dị ala na-eme. Ọzọkwa, n'ime ndị nwere ọrịa shuga phosphate, mkpụmkpụ mkpụmkpụ, ọrịa na akụkụ ndị ọzọ nke ọkpụkpụ na-achọpụta, enwere ike ịgbanwe agbanwe, ihe mgbu n'oge mmegharị.

Akwara hypotension, njiri mara ezi rickets, anaghị adịkarị n'ọrịa shuga phosphate. Mmepe ọgụgụ isi nke ọrịa a anaghị ata ahụhụ.

Mkpakọ

N'ihi ọgwụgwọ a na-adịghị akwụ ụgwọ, ndị ọrịa nwere ọrịa a nwere ike ịnata nsogbu ndị a:

• Mmebi nke spain, n'ihi ya - postcho.
• Uche uche ma ọ bụ nke anụ ahụ na mmepe nwata.
• Ọkpụkpụ ma ọ bụ nrụrụ akwara na-eduga nkwarụ.
• Nkuzi nke mmepe nke ezé, imebi oge mmepe ha.
• Ọgba aghara na mmepe nke ossicle auditory.
• Nephrocalcinosis, nke kọwara site na nkwakọba nnu nnu na akụrụ.

Ọ bụrụ na nwatakịrị ahụ nwere ihe ga - eme mmepe nke ọrịa a, mgbe ahụ nyocha ya na-amalite ihe fọrọ nke nta site n’ọmụmụ, iji gbochie nsogbu dị ka o kwere mee. Iji mee nke a, ha na-enyocha ọkwa nke calcium na phosphorus, na-ahụ otú ọkpụkpụ ahụ si etolite, ma uto ya kwekọrọ n’ụkpụrụ ndị kwesịrị ịdị n’oge a.

Mgbe achoputara akara nke mbu nke oria phosphate, umuaka ka edobere inye vitamin. Ọ bụrụ na achọrọ, ndị nne na nna nwere ike ịhazi oke uru nwatakịrị ahụ ị nweta ọgwụ n'efu, yana hazie njem efu na ogige nlekọta ahụike pụrụ iche.

Kedu dọkịta m kwesịrị ịga?

Ọ bụrụ na a na-enyo enyo ọrịa shuga phosphate, ọ dị mkpa ịkpọtụrụ dọkịta na-ahụ maka ụmụaka, mgbe nyocha nke mbụ, ga-eduga nwatakịrị ahụ maka ịgakwuru onye ọrịa endocrinologist, orthopedist, na nephrologist. Ọgwụgwọ a gụnyere masseur, physiotherapist, ọkachamara na usoro mmega ahụ na usoro ọgwụgwọ. Ọ bụrụ na ọ dị mkpa, dọkịta na-awa ahụ ga-awa ahụ.

A na-eji salts phosphoric acid nke calcium na sodium na-agwọ ọrịa shuga na ụmụaka na kilogram 10 nke phosphate kwa 1 n'arọ nke ahụ́ nwatakịrị ahụ ugboro 4 kwa ụbọchị. A na-ewere ọgwụ ọjọọ n'ụdị edozi ma ọ bụ mbadamba.

Iji gbochie mmebi nke metabolism metabolism, a na-enye vitamin D .. A na-eji ya amalite site na usoro nke 0.005 μg ma na-abawanye 0.03 μg kwa 1 kilogram nke ahụ. N'otu oge ahụ, ọkwa nke phosphorus n'ime ọbara na-ebili, ọrụ nke alkaline phosphatase na-ebelata.

Iji gbochie itinye salts nnu n'ụdị okwute, akwara a na-achịkwa ọkwa dị na ọbara na mmamịrị. Site na iji ụkpụrụ nkịtị, ị nwere ike jiri nwayọ mee ka ọnụọgụ vitamin D dịkwuo elu.

Na mgbakwunye na vitamin D, a na-atụ aro ka ndị ọrịa dị otú a:

• phosphorus na nhazi nke calcium,
• ngwakọta nke citrate (n'ime ọnwa isii iji meziwanye nnabata ndị a na - achọpụta).
• homonụ na-eto.

N'ime oge dị ukwuu nke usoro ahụ, a na-adụ ndị ọrịa ọdụ ka ha hie ụra, mgbe ha nwesịrị mgbaghara - ọgwụgwọ ịhịa aka n'ahụ, mmega ahụ a na-eme na spa spa.

Ihe nlebara anya maka odi nma na nti ajuju bu:

• ọdịmma,
• osooso nke uto,
• nkịtị usoro nke site na metabolism nke phosphorus n'ime ahụ,
• ezigbo rediological radio (weghachite usoro ọkpụkpụ).

Ọnụnọ nrụrụ ọkpụkpụ na –emebi ndabere nke mgbatị ahụike na ụlọ nyocha ugboro ugboro, a na-eme mgbazi ha. Enwere ike iji usoro ndị a maka nke a:

• osteotomi (dissection) nke ogologo ọkpụkpụ toubu na ndọtị nke eriri aka ya,
• mgbochi nke Ilizarov ndọpụ uche na ngwa mkpakọ.

Ekwesịrị ịrụ ụdị ọrụ ahụ naanị mgbe ọgwụgwọ ogologo oge na nyocha nke ogologo oge gasịrị.

Iotzọ ọgwụgwọ anụ ahụ maka ọrịa shuga phosphate

Usoro ọgwụgwọ eji eme ka ọnọdụ ahụ belata:

1. Usoro ọgwụgwọ Laser Treatmentzọ ọgwụgwọ a na - eme ka nkwonkwo kwalite nkwonkwo ma belata ihe mgbu na ha. Thezọ akọwapụtara sitere na mmetụta nke radieshon laser na anụ ahụ. Na nke a, a na-ewepụ usoro mkpali, usoro ịmụgharị na-agbatị. A na-enye okporo osisi laser nri mpaghara nsogbu ahụ site na iji mgbanye pụrụ iche.
2. Magnetotherapy. Usoro a na - enyere gị aka ime ka usoro ahụ ji alụso ọrịa ọgụ dị mma, melite ahụike n'ozuzu ya ma mee ka mweghachi nke anụ ahụ sie ike. Usoro ọgwụgwọ a sitere na mmetụta magnetik n'ahụ ahụ mmadụ.
3. Electrophoresis Na-ebelata ihe mgbu na nkwonkwo na ọkpụkpụ. Usoro a dabere na ikike nke ọkụ eletrik na-eduzi ọgwụ ọgwụ na mpaghara emetụtara. N'okwu a, agagharị na mpaghara mmetụta na-abawanye. Epekele pụrụ iche na -eme ugbu a n'elu nkwonkwo nsogbu, ebe ejiri ọgwụgwọ mbụ gwọọ ya.
4. Ultraphonophoresis. Ọ dị ka usoro gara aga, Otú ọ dị, ọgwụ dị na nke a rute mpaghara nsogbu n'ihi oke ikuku ultrasonic. Iszọ ahụ dị nchebe kpamkpam na enweghị mgbu.

Prognosis nke ọrịa shuga phosphate nwere ike ịdị iche ma dabere n'ọtụtụ ihe - ụdị ọrịa, ogo mgbaàmà, afọ nke ịchọpụta ọrịa na mbido ọgwụgwọ ọfụma. Ọtụtụ mgbe, prognosis ahụ dị mma, mana ịchọrọ ndụ ogologo oge niile nke iji vitamin D, calcium na phosphorus nwere ike ịdịgide. Ọkpụkpụ akwara siri ike na-esite na ịchọpụta ọrịa ma ọ bụ ọgwụgwọ na-ezighi ezi nwere ike imebi ndụ onye ọrịa.

Mgbochi

Ọrịa shuga phosphate bụ ọrịa a na-ekesa n'ihe fọrọ nke nta ka ọ bụrụ n'ọnọdụ niile site n'aka ndị nne na nna na-arịa ọrịa na ụmụaka. Ọ bụrụ na ọdịdị ya sitere n’ọrịa sitere n’ọmụmụ, mgbe ahụ mmadụ ma ọ bụ dọkịta ọ bụla ruru eru agaghị enwe ike ime ka mmepe ya pụọ ​​ma wezuga ihe ize ndụ nke ọrịa.

Mgbochi nke usoro ogwu a bu iji gbochie omume nke nsonaazụ na ibelata ihe ize ndụ nke nrụrụ ọkpụkpụ na ndị ọrịa nọ n'afọ ndụ dị iche iche.

Na ọnụnọ ọrịa shuga phosphate na ndị ikwu dị nso, ọ dị mkpa ịga leta mkpụrụ ndụ ihe nketa na ọkwa nke ịtụrụ ime. Ọ dị mkpa ịmata proband - onye onye akụkọ banyere ọrịa ezinụlọ malitere.

Mmega ahụ

Site na ọrịa shuga phosphate, ọ dị ezigbo mkpa iji bie ndụ na-arụ ọrụ. E gosipụtara ndị ọrịa nwere ọrịa a:

• Omume ụtụtụ, nke kwesịrị ịgụnye mmega maka ogwe aka, ụkwụ, spain:
  • ije ije na ebe
  • Squats
  • legskwụ na ogwe aka
• ịnyịnya ígwè
• igwu mmiri, nke na-ewusi akwara ike, na-ebelata ihe mgbu, nwere uru bara uru na sistem.

  

  Igwu mmiri na-eme ka ụda olu dịkwuo elu, na-eme ka ọrụ akwara ike

  Ndụ mamịrị na-arịa ọrịa shuga phosphate na-eme ka mmepe nke atrophy muscle ike.

  Nkịtị

  Ọrịa ịgwọ ọrịa phosphate dị mma gụnyere:

  • ịhịa aka n'ahụ nke ala na elu akụkụ, nke a na-eme ka mgbasa ọbara kawanyewanye, ụda olu na-ahazi,
  • mmega ahụ.

  Na mbu, ndi okacha mara n’ulo ogwu gha eme ya. N'ọdịnihu, ndị ezinaụlọ nke onye ọrịa ahụ nwere ike ịmụta usoro ịhịa aka n'ahụ ziri ezi ma rụọ usoro ahụ n'ụlọ.

  A na-ahọpụta ihe mgbagwoju anya nke usoro mmega ahụ maka ndị ọrịa n'otu n'otu maka ndị ọrịa ọ bụla. Oge izizi kwesiri ime n'okpuru nlekọta nke ọkachamara, mgbe enwere ike ịme mgbatị ahụ n'ụlọ.

  Nri nri

  Usoro ọgwụgwọ nri bụ ihe dị mkpa na ọgwụgwọ nke ọrịa mamịrị Fofat, nke ga - enyere aka:

  • emezie metabolism
  • melite ọnọdụ ọkpụkpụ na akwara anụ ahụ.

  Na ọrịa shuga phosphate, menu kwesịrị ịgụnye ngwaahịa:

  • nwere otutu ivu
  • rizikalị calcium.

  Tebụl: nri bara uru maka ọrịa shuga phosphate

  Ihe oriri dị elu na Phosphorus	Calcium Ọgụrụ
  azu azu soybeans lentil agwa chiiz akwa.	obi chiiz chiiz agwa mkpụrụ sesame almọnd mkpọ salmon na sardines, kabeeji akwụkwọ nri pasili rhubarb.

  Ewepu nri kwesịrị iri nri nke ka akarị akụrụ na akụrụngwa obi:

  • nnu, nke na - emebi ahụ, ma na - emetụta sistemụ ahụ niile,
  • nri mara abụba. Iri oke abụba n’ime nri na-abawanye cholesterol n’ime ọbara, nke nwere ike ibute mmepe nke ọrịa vaskụla. Ọzọkwa, nri ndị nwere abụba na-eme ka metabolism dịkwuo elu, na-abawanye ibu dị na akụrụ,
  • oseose, pickled, smoked nri. Ngwaahịa ndị dị otú a na-akpasu akpụkpọ ahụ mucous nke urinary tract,
  • mmanya Ihe ọ Alụ Alụ na-egbu egbu na-abawanye ọbara mgbali, na-eme ka mmepe nke arrhythmia, jiri ihe ndị na-egbu egbu meju anụ ahụ.

  Prognosis ọgwụgwọ yana nsonaazụ ọ bụla

  Nnyocha nke ọrịa shuga phosphat na-adabere n'akụkụ ndị a:

  • na oge ichoputa oria,
  • mmuta nke usoro ọgwụ enyere,
  • omume ziri ezi nke onye ọrịa ma ọ bụ ndị mụrụ ya (ọ bụrụ na anyị na-ekwu maka nwatakịrị nwere ọrịa phosphate).

  Ọrịa shuga phosphate na-enwekarị:

  • urolithiasis,
  • osteoporosis (ogo nke ogo ọkpụkpụ).
  • scoliosis (curvature of the spinal column),
  • arrhythmia (obi mgbawa obi),
  • ọbara mgbali ọbara (mgbali elu na-arịa ọbara mgbali elu),
  • ogwe aka nke ukwu aka ya.

  Ihe na-ewute kacha njọ bụ enweghị ike onye ọrịa kpamkpam.

  Ihe na-akpata Ọrịa shuga Phosphate

  Dabere na ihe kpatara phosphate, ọrịa shuga nwere ike ikpebi site n’ọmụmụ ma bufee ya n’aka ndị nne na nna na-arịa ọrịa ma ọ bụ bụrụ ngosipụta nke etuto ahụ (oncogenic rickets).

  Hypophosphatemic rickets na-adị na mbelata phosphorus site na mmamịrị mbụ ya, yana nsị nke calcium na phosphat na-emetụta site na eriri afọ, mbelata na mkpokọta vitamin D yana mmegharị ya na imeju. Mbelata na ọrụ nke mkpụrụ ndụ na - akpụpụta akwara ọkpụkpụ (osteoblasts) na - eduga n'eziokwu ahụ na ọkpụkpụ nwere usoro na - akpata ọgba aghara.

  Aremụaka na-arịa ọrịa na ọnụnọ nke otu ọrịa na nne na nna ha. Enweghị ụzọ ọ bụla akọwapụtara maka igbochi ọrịa ahụ. Ọ bụrụ na nna ahụ na-arịa ọrịa, ọ na-enyefe nwa ya nwanyị ọrịa phosphate, ụmụ nwoke na ụmụ ndị nwanyị nwere ụdị mmepe ahụ nwere ike ịmụ nne site na nne na-arịa ọrịa. A na-ejikọ ihe ọmụmụ sitere na ọrụ nke osteoblasts na ọdịnaya phosphorus n'ime ọbara na chromosome X.

  Nke kachasị njọ, ụmụ nwoke na-ata ahụhụ site na hypophosphatemic rickets. N’oge agadi, ọrịa ahụ nwere ike jikọta ya na akpụ n’ime ọkpụkpụ ma ọ bụ anụ ahụ dị nro.

  Na ọrịa shuga phosphate, nsogbu ndị dị otú ahụ malitere:

  1. Ọkpụkpụ
  2. Ikwu dị nro
  3. Mgbanwe nke nkwonkwo ụkwụ na ikpere
  4. Ọkpụkpụ mkpụkpụ ụkwụ aka.

  Ihe ịrịba ama nke ọrịa shuga phosphate dị na nwata

  Hypophosphatemic rickets nwere ike ịmalite mgbe ọ bụ nwata, ọ na-abụkarị mgbe nwa ahụ bidoro ije ije n'adabereghị. Tupu nke a, ọnọdụ izugbe nwere ike ịnọgide na-adị ọfụma ma ghara ibute ndị dọkịta na-enyo enyo.

  Ihe ịrịba ama nke mbụ bụ nwatakịrị ahụ achọrọ, yabụ imetọ ya n’ọkpụkpụ mgbe ọ na-eje ije. Maymụaka nwere ike jụ ịgagharị n'enweghị enyemaka. N’ọdị n’ihu, ụkwụ na-echilata na usoro nke ikpere na nkwonkwo nkwonkwo na-ama jijiji, ọkpụkpụ na mpaghara aka

  Ihe ngosi ndị dị otú a jikọtara ya bụ mmebi nke iguzosi ike n'ezi ihe nke enamel nha nzụlite na otutu nke nnabata, oke ọkpụkpụ na ọkpụkpụ pelvic.

  Ihe ozo bu njiri mara nke ọrịa mamiri Fofat bu:

  • Uda olu adalatala.
  • Spasmophilia.
  • Ọkpụkpụ n’ụdị n’ụkwụ.
  • Ọkpụkpụ na-emebi emebi na nrụrụ ọkpụkpụ.
  • Eningkpụpụ ụkwụ nke aka, oge anaghị agbasa

  Nchoputa nke oria

  Nnyocha x-ray kpughere diaphisation buru ibu (akụkụ nke ọkpụkpụ tubular), njupụta nke ọkpụkpụ, osteoporosis, ịkpụkpụ ọkpụkpụ, ọkpụkpụ nwere oke calcium.

  Otu njiri mara ọrịa a na-achọpụta bụ enweghị nzaghachi na ịsesụ ọgwụ vitamin D, n'adịghị ka ọrịa rickets, yana ọrịa phosphate, ojiji a anaghị ebelata ihe mgbaàmà nke ọrịa.

  Ọzọkwa, mgbe ị na-eme nchọpụta, nchọpụta nke phosphates na mmamịrị dị ọtụtụ oge karịa ụkpụrụ nkịtị.

  Nyocha ọbara na-ekpughe ihe ndị dị n’ime foshorus dị ala. Iji wepu ọrịa nke ọrịa parathyroid gland, a na-enyocha ọkwa nke homonụ parathyroid. Site na ọrịa shuga phosphate, ọ na-adị elu ma ọ bụ na-enweghị oke. Ihe onyonyo gosiputara homonụ parathyroid na-egosiputa mbelata nke akwara gbasara akụrụ.

  Na mgbakwunye, na ndị ọrịa, enwere ike ịchọpụta ọrụ alkaline phosphatase mgbe ụfọdụ na obere calcium n'ọbara ma ọ bụrụ na edepụtara ọrịị nke phosphorus dị elu.

  Ọrịa shuga Phosphate

  A na-eji salts phosphoric acid nke calcium na sodium na-agwọ ọrịa shuga na ụmụaka na kilogram 10 nke phosphate kwa 1 n'arọ nke ahụ́ nwatakịrị ahụ ugboro 4 kwa ụbọchị. A na-ewere ọgwụ ọjọọ n'ụdị edozi ma ọ bụ mbadamba.

  Iji gbochie mmebi nke metabolism metabolism, a na-enye vitamin D .. A na-eji ya amalite site na usoro nke 0.005 μg ma na-abawanye 0.03 μg kwa 1 kilogram nke ahụ. N'otu oge ahụ, ọkwa nke phosphorus n'ime ọbara na-ebili, ọrụ nke alkaline phosphatase na-ebelata.

  Iji gbochie itinye salts nnu n'ụdị okwute, akwara a na-achịkwa ọkwa dị na ọbara na mmamịrị. Site na iji ụkpụrụ nkịtị, ị nwere ike jiri nwayọ mee ka ọnụọgụ vitamin D dịkwuo elu.

  Ọzọkwa, a na-egosi ndị ọrịa dị otú a ahazi nke nhazi calcium. Iji melite ntopute nke salts nke site na calcium si na eriri afọ lumen ha na-agwakọta na citric acid. Tinye Calcium Gluconate, Fitin, Calcium Glycerophosphate, Sodium Citrate. A na-eme ọgwụgwọ ahụ ogologo oge - ọnwa isii.

  Na mgbakwunye, usoro ọgwụgwọ ndị a ka enyere ndị ọrịa:

  1. Ọgwụ Vitamin na tocopherol (vitamin E) na vitamin A.
  2. Nhọrọ nke ogwugwu nke akwara orthopedic maka idozi curvature nke spain.
  3. Na ngwụsị nke uto, a pụrụ ịmalite ime ọgwụgwọ nke ọkpụkpụ na-eme ka ọkpụkpụ ọgwụgwọ dị ukwuu.
  4. Site na ọrịa shuga oncogenic foseti, a na-ewepụ etuto ahụ.

  N'ime usoro ọrịa a nwere oke mgbu na ọkpụkpụ, spain na nkwonkwo, a na-enye ndị ọrịa ọgwụ ezumike. Ọ na-abụkarị ụbọchị iri na ise. A na-atụ aro iji ọgwụ ndị na-egbu mgbu na ọgwụ mgbochi mbufụt.

  Mgbe ọrịa ahụ gaferela nkwụsi ike nke ụlọ ọgwụ na mgbatị ahụ, a na-enye ndị ọrịa iwu ka ọ na -emega ahụike yana mmachi nke ịwụ elu na mmega ahụ siri ike.

  A na-atụ aro ka ọ na-eduzi usoro ịhịa aka n'ahụ, ịsa ahụ nnu na-agagharị na mmiri ikuku, ọgwụgwọ na ọnọdụ sanatorium.

  Ihe na nsonaazụ ya

  A na - amata ụdị ọrịa anọ dabere n'ụdị nsogbu metabolic. Abụọ na ọdịiche abụọ nke ọrịa ahụ dị mma (gbasara ịkọ ogologo oge). Nhọrọ nke mbu bidoro n’afọ mbụ nke ndụ, obere nrụrụ ọkpụkpụ, a na-anabata vitamin D nke ọma. E jikọtara ya na mkpịsị nke phosphorus na calcium yana mmamịrị na feces.

  N’ime mgbanwe nke abụọ, ọrịa ahụ bidoro n’afọ nke abụọ nke ndụ, akpọpụtara mgbanwe mgbanwe ọkpụkpụ, a na-ebelata phosphorus n’ime mmamịrị. Vitamin D na-egosi nguzogide. A na-enwekarị ọgwụ phosphorus ebe ọ bụ na mmebi akụrụ mere na ọrịa mellitus. A na-ebelata uto nke ụmụaka, ahụrụ ahụ siri ike. Ihe ngosi X-ray nke rickets, nro n’ọkpụkpụ.

  Nhọrọ nke atọ na-amalite mgbe ọ dị afọ ise, ọkpụkpụ na-emebi emebi nke ukwuu, a na-ebelata kalsel dị n’ọbara, a na-etinyekwa calcium na phosphates n’ime eriri afọ. Vitamin D gosipụtara nguzogide.

  Aremụaka na-echefu echefu, ezé nwere ntụpọ na enamel, na-enwekarị nsogbu. A na-agbadata ọkwa nke kalsia ọbara, a na-ahụkwa ọtụtụ amino acid na mmamịrị. E nwere ihe iriba ama nke hyperfunction nke abụọ nke gall parathyroid. Nyocha x-ray na-ekpughe mgbanwe n’akụkụ uto ọkpụkpụ, osteoporosis.

  Ejiri nhọrọ nke anọ mara nsiwanye ike na vitamin D na ebumnuche nke hypervitaminosis, ọbụlagodi mgbe e jiri ya mee obere ọgwụ. Site na mgbe nwata bụ, etinyere mbọ ụkwụ, isi nkwọcha na mmebi ezé.

  Ihe ojoo nke oria phosphate gụnyere:

  • Mmebi nke postcho na deformation nke ala nsọtụ.
  • Nkịtị ma ọ bụ oge mgbagha echiche.
  • Ọkpụkpụ na ezé etolite etolite.
  • Calcium na akụrụ.
  • Ihe isi ike na nnyefe (a chọrọ ngalaba caesarean).

  Mgbochi oria a na-eme na nyocha nke mkpụrụ ndụ ihe dị na nhazi nke ịtụrụ ime, ọkachasị ma ọ bụrụ na enwere ụdị ikpe ahụ dịka agbụrụ dị n’ime ezinaụlọ ma ọ bụ ndị ikwu. Ebe a na - enye ndị mmadụ ọrịa mkpụrụ ndụ ihe nketa nwere ike ibute nsogbu nke ikesa ọrịa shuga phosphate.

  Ọ bụrụ na nwatakịrị ahụ nọ n'ihe ize ndụ, mgbe ahụ, a na-enyocha ya site na ịmụ nwa, na-enyocha ọkwa nke phosphorus na calcium n'ọbara na mmamịrị, ma na-enyocha usoro nke ọkpụkpụ, na-agbaso ụkpụrụ nke afọ, nyochaa mmeghachi omume na ịnweta ọgwụ vitamin D. Na ọnụnọ nke ihe ịrịba ama mbụ nke ọrịa ahụ, a na-enye ụmụaka iwu. ọgwụ vitamin. Ndị nne na nna kwesịkwara itinye akwụkwọ maka uru maka nwatakịrị nwere ọrịa mellitus ma nata ọgwụ na njem n'efu na ebe nlekọta ahụike.

  Na vidiyo dị n'isiokwu a, Dr. Komarovsky na-ekwu maka ụkọ vitamin D.

  Ebumnuche na ihe mmepe

  Isi ihe kpatara ọrịa ahụ bụ nsị nsị akịrị nke akwara sitere na mmụba mkpụrụ ndụ ihe nketa. Anzọ na-ezighi ezi nke nwanyị dị ime, ihe ọictionụ toụ na-aba n'anya ya, na iji ụtaba ma ọ bụ ọgwụ ọjọọ nwere ike ịkpasu usoro a na-arịa ọrịa. E nwere nsogbu nke nsogbu ndị a na-aba ụba na ndị ndị ikwu ha nwere ọrịa shuga phosphate. N'otu oge, ọ gaghị ekwe omume izere ihe nketa nke ọrịa dị otú ahụ.

  Ihe ndị ọzọ na-akpasu iwe:

  • na-ewere ọgwụ siri ike n'oge ọnwa atọ nke ịtụrụ ime,
  • oke nsi,
  • ọgba aghara

  Dika onu ogugu si di, na otutu ihe, ana ebunye oria site na nna rue nwa nwanyi n’agbanyeghi na enwere udiri ihe nketa na nne.

  Foto nyocha

  N'ime afọ 1-2 mbụ nke ndụ, pathology enweghị ike igosipụta n'ụzọ ọ bụla. Naanị ihe na-egosi na ọrịa ahụ bụ ụba ọdịnaya phosphorus ion na mmamịrị. Mgbe nwata ahụ malitere ije ije, mgbe ahụ usoro ọmụmụ na-eme onwe ya. N'okwu a, ụkwụ nwere nkwarụ, nke na-enweta ọdịdị-O. Nwa ahụ nwekwara nkwarụ ike yana enweghị ike ịme ihe ọ bụla.

  • ugba uto
  • adịghị ike anụ ahụ
  • ntutu isi
  • nha ezé
  • oke mgbu mgbu
  • ọgwoga oge niile.

  

  Ọrịa shuga phosphate na-eme ka ọkpụkpụ na-adị nro ma na-emebi emebi

  Ọ bụrụ na agwọghị ya, ọrịa ahụ na-aga n'ihu, oke ihe mgbu na ọkpụkpụ na nkwonkwo na-eme, n'ihi nke nwatakịrị ahụ tụfuru ikike ịmegharị ahụ niile.

  Zọ nyocha

  Zọ nyocha iji eme ihe iji chọpụta nchọpụta ọrịa:

  1. Nyochaa mmamịrị na ọbara. Ọ na - enye ohere ịchọpụta ọkwa phosphorus na plasma na mmamịrị. N'okwu nke mbụ, ọnụọgụ nke ion na-agbada n'ụzọ dị egwu, na nke abụọ, n'ụzọ megidere, ọ na-abawanye. Foto a na-enyere anyị aka iche na ọnụnọ ọrịa shuga phosphate dị.
  2. CT na MRI. Ntụgharị uche tomography na-eme ka o kwe omume ịchọpụta ọrịa na ọkpụkpụ. N'otu oge ahụ, enwere ike ịhụ nrụrụ ọ bụla na eserese a. Ihe onyoonyo magnetik yiri igwe onyonyo atule, naanị mgbe ejighi ya, a na-eji ese ụzarị ọkụ, mana ihe ndọta nuklia. Iji usoro a, ị nwere ike nweta onyonyo nke ọma karịa nyocha dị iche iche nke ọkpụkpụ na nkwonkwo.
  3. X-ray. Ọ bụ usoro nyocha mgbe ochie na imebi ihe ọkpụkpụ. Na eserese ị nwere ike ịhụ njiri mara ọrịa a. N'okwu a, ọkpụkpụ na-adị gịrịgịrị ma na-enwegide nrụgide.

  

  MRI bụ otu n'ime usoro nyocha dị oke ọnụ ma na-enye ihe ọmụma maka ọrịa shuga phosphate.

  Ọzọkwa, enwere ike iji nyocha nke ultrasound nke akụrụ, ebe enwere obere mgbanwe ọrịa na-ahụ na nhazi nke akụkụ ahụ. N'okwu a, ị nwere ike ịchọta ájá na nkume, jikọtara ya na ọrịa a.

  Usoro ọgwụgwọ

  Usoro ogwu a enweghị ike ịgwọ ọrịa, mana site na iji usoro ọgwụgwọ agbakọta, ọ ga-ekwe omume ịkwụsịtụ ọrịa ahụ. Maka ebumnuche ndị a, a na-eji ọgwụ, physiotherapy na nri nri. Dịka usoro inyeaka, a na-eji usoro ndị ọzọ eme ihe. N'ọnọdụ ndị dị elu, jiri usoro ịwa ahụ mee ihe. Ihe mmanye bu ikiri akwara orthopedic - ihe mgbochi na - egbochi imebi na iguzogharia aru.

  

  Banyere Phosphate Ọrịa Shuga Na-egbochi Ọrịa Spinal

  Nchikota nke ogwu ogwu na physiotherapy nwere ike melite onodu ahuike nke onye oria, ma wepu ma obu belata ihe mgbu.

  Ọgwụ ọgwụ

  A na-eji otu ọgwụ dị iche iche na-agwọ ọrịa:

  1. Nkwadebe nke nwere sọlfọ phosphate nnu: Osteogenon, Tridine, wdg ọgwụ ndị dị otú a na-eme ka ọnọdụ nke anụ ahụ dịkwuo ala, na-egbochi mmebi ọzọ na mgbanwe nke ọrịa na nkwonkwo. Edere ọgwụ maka ogologo oge (site na ọnwa 6 ma ọ bụ karịa).
  2. Vitamin D: Aquadetrim, Ultra-D, wdg Ọgwụ na otu a dị mkpa maka nnabata phosphorus ion zuru oke ma belata mmụcha ha na mmamịrị. O jiri nwayọ na-abawanye nke vitamin, usoro ọgwụgwọ dịkwa ogologo.
  3. Nkwadebe Calcium: Fitin, glucose glucose na ndị ọzọ. Ogwu sitere na otu a na - ewusi ọkpụkpụ ike, na - egbochi mgbanwe ọrịa ma melite ọnọdụ nke ezé. Ọgwụ ndị a mejupụtara ụkọ nke kalsel na ndị ọrụ ya na-efu. Nke a na - eme ka ọdịmma ọrịa phosphate dịkwuo mma. Usoro ọgwụgwọ sitere na ọtụtụ ọnwa ruo ọnwa isii.
  4. Vitamin E: Tocopherol acetate, Aevit na ndi ozo. Ogwu sitere na otu a nwere mmetụta antioxidant, mee ka ahụike ka mma ma nwee ọfụma na ọnọdụ nke akụkụ ahụ niile.

  Ọgwụ ọgwụ nwere ike igbochi ọganihu nke ọrịa ahụ ma na-enyere aka ime ka ọkpụkpụ sikwuo ike, na -ebelata mfu nke phosphorus na calcium na mmamịrị.

  Gerywa ahụ

  Resowa ahụ bụ ụkwụ nwere ụkwụ nwayọ nwayọ nwayọ gboo ụkwụ. Nke a dị mkpa mgbe usoro ndị ọzọ dara. Nwere ike ịmalite usoro ọgwụgwọ a naanị mgbe ngwụcha uto ọkpụkpụ gasịrị. Site na itinye aka na ịwa ahụ, a na-edozi ụkwụ ndị nwere nrụrụ site na iji agịga pụrụ iche. Nke mbu, a na-agafe ọkpụkpụ, ya bụ, agbajiela ma kewapụ ya n'ọnọdụ ziri ezi. Mgbe ahụ dozie mpaghara a chọrọ site na iji ihe owuwu ọla (usoro Ilizarov).

  Iweghachite di ogologo. A na-arụ ọrụ a n'okpuru nkụnwụ ahụ. A naghị ewepụ agịga ahụ n’ọkpụkpụ ruo mgbe etinyere ya kpam kpam n’ebe dị mma. Site na usoro a, ị nwere ike iwepu ihe mgbu niile oge. Na nwute, na nrụrụ siri ike, a gaghị etinye usoro a mgbe niile.

  

  Mmezi nke nrụrụ ọkpụkpụ mgbe a wasịrị ya ahụ dịka usoro Ilizarov si dị

  Dọkịta kpebisiri ike ịchọpụta ịwa ahụ ọfụma ọfụma. Site na mbibi dị ukwuu nke anụ ahụ, usoro ọgwụgwọ a chọrọ iji weghachi mpaghara ndị emetụtara.

  Wa ahụ na-enye gị ohere iwepụsịsịsị ịka ụkwụ, nke na-eso ndị ọrịa shuga phosphate mgbe mgbe.

  Klọ ọgwụ ndị na-ewu ewu

  Ebumnuche a bụ ime ka ahụ sie ike ma meziwanye usoro metabolic. Ntụziaka ndị a enweghị ike iwepụ ọrịa shuga phosphate ma anaghị emetụta oriri nke phosphorus. Uzo ozo eji eme ihe iji meziwanye onodu akụrụ na aru ya dum:

  1. Nri ngwakọta. Na-emezigharị adịghị ike nke Chọpụta ihe, na-eme ka usoro ahụ ji alụso ọrịa ọgụ gharazie isi ike. Ga-achọ walnuts, almọnd na osisi haelnuts n'ụdị kpọrọ nkụ. Ekwesịrị ịgwakọta ihe niile dị nha (100 g nke ọ bụla), wee tinye 2 tbsp. l mmanụ a .ụ. A na-atụ aro ka ngwakọta a ga-aghọrọ ghee na blender ma jiri 1 tbsp. l 3 ugboro n'ụbọchị 1 awa mgbe nri. Usoro ọgwụgwọ ya bụ ọnwa 1.
  2. Inye infusion. Ọ na - eme ka ahụ sie ike, na - eme ka akụrụ arụ ọrụ. Ga-achọ ọka ọka n'ọnọdụ ego 1 tbsp. l., nke kwesịrị ịwụnye 300 ml nke esi mmiri ma hapụ ya ka ime biya ruo awa 2. Yụzie mmiri mmiri ahụ ma were 100 ml ugboro 3 n'ụbọchị 15 tupu nri. Usoro ya bụ izu abụọ.
  3. Efere mgbochi mkpali. Ọ na - eme ka akụrụ arụ rụọ ọrụ, na - ewusi usoro ahụ ji alụso ọrịa ọgụ ọgụ. Willkwesiri ịgwakọta nha nke chamomile na okooko osisi calendula. 1 tbsp. l wunye 400 ml nke esi mmiri na obụpde n'elu obere okpomọkụ maka minit 15. Mgbe ahụ, mee ka mmiri mmiri dị jụụ ma nyo. Njikere dị njikere iji 100 ml ugboro 3 otu awa n'otu awa mgbe ị risịrị nri. Usoro ya bụ ụbọchị iri.
  4. Ọgwụ ịsa ahụ. Ọ ga - enyere aka wepu mgbu n'ime ọkpụkpụ na nkwonkwo. Ọ dị mkpa ịpịa bat, mmiri ọkụ nke ekwesighi gafere ogo 41. Na 2 tbsp. l nnu nnu dị gị mkpa ịgbakwunye 3 tụlee nke paini mmanụ dị mkpa. Isi ihe bụ ịghara imebiga ya ókè! Ekem igbari nnu na mmiri. Jiri mmiri saa ahụ were minit 15-20. Tinyegharịa usoro a ka achọrọ.

  Enweghi ike iji ọgwụgwọ ndị nwere isi na-emeso ụmụaka na-erubeghị afọ 12. Ezubere usoro ndị a maka naanị ndị okenye. Echefula na ahụ ụmụaka nwere mmetụta nke ukwuu ma ọ nwere ike ọ gaghị anabata ụzọ ndị a ga - esi gwọọ ya n'ụzọ kachasị mma.

  Prognosis na nsogbu

  Site n’ichekwa ọgwụgwọ n’oge, prognosis ahụ dị mma. Ciumnweta calcium, vitamin D na phosphorus mgbe niile na-enyere aka ịbawanye mma. Agbanyeghị, a ga-ewere ihe ndị a ruo na njedebe nke ndụ dịka ọgwụgwọ mmezi. Ọ bụrụ na ọrịa a bidoro, mgbe ahụ ị nwere ike ịhụ ọtụtụ nsogbu, dịka:

  • nkwarụ aka ukwu
  • spinal curvature,
  • ọnya na-adịgide adịgide ọbụlagodi na obere ọnya ahụ dara,
  • ọgba aghara,
  • ịkpụ akụrụngwa akụrụ.

  Amalitere ọgwụgwọ izizi maka ọrịa shuga phosphate, ka mma maka nwata ahụ. Ọ bụrụ na achọpụtara ọrịa ahụ n’afọ mbụ nke ndụ ma n’otu oge ahụ a na-eme ọgwụgwọ kwesịrị ekwesị, mgbe ahụ ihe egwu nke nsonaazụ ndị dị ize ndụ dị ala.

  Ihe mgbochi

  Ọ dị nwute, ọ gaghị ekwe omume igbochi ọrịa shuga phosphate, ebe ọrịa ahụ bụ ihe nketa. Agbanyeghị, ịnwere ike belata ihe egwu ga-ebute anụ ahụ, ma ọ bụrụ na ị na-agbaso iwu dị mfe nke mgbochi:

  1. Rie nke ọma ma drinkụọ ọtụtụ mmiri.
  2. Were ogige vitamin nke nwere vitamin D, calcium na site.
  3. Dọkịta ga-enyocha gị mgbe niile: nyochaa ule ọbara na mmamịrị, wee nyochaa akụrụ.
  4. Ọtụtụ mgbe ị ga na-na ikuku.
  5. Ejila ọgwụ ike ị na-enweghị ọgwụ dọkịta.

  

  Nyocha ọbara na-enye gị ohere ịchịkwa ọkwa nke phosphorus

  Iji belata ihe egwu dị na nwa a na-amụbeghị amụ, ọ dị mkpa ịgakwuru onye mkpụrụ ndụ ihe nketa mgbe ị na-eme atụmatụ ịtụrụ ime.

  Ọrụ nke vitamin D na mgbochi ọrịa ụbụrụ phosphorus metabolism - vidiyo

  Ọrịa shuga Phosphate bụ ọrịa siri ike nke nwere ike ibute nrụrụ ọkpụkpụ. N'otu oge, mmadụ na-enwe ọ bụghị naanị ọrịa anụ ahụ, kama ọ na-enwe ahụ erughị ala, ya mere ọ dị oke mkpa ịhapụ ileghara ihe ịrịba ama mbụ nke ọrịa. Drugs drugsụ ọgwụ vitamin nwere ogologo oge ga - enyere aka ịka mma.