Humulin® M3 (Humulin® M3)

Aha ahia nkwadebe: HUMULIN ® Regular

Aha International nonproprietary (INN):
Ngwọta insulin (injinị mkpụrụ ndụ mmadụ)

Mpempe usoro onunu ogwu
Ngwọta maka ntụtụ

Ngwakọta
1 ml nwere:
ike ihe - insulin mmadu 100 IU / ml,
ndị mbụ: enwere ike iji metacresol, glycerol (glycerin), mmiri maka ntụtụ, hydrochloric acid solution 10% na / ma ọ bụ sodium hydroxide 10% nwere ike iji rụọ ọrụ iji guzobe pH.

Nkọwa
Azịza transperent enweghị enweghị ntụpọ

Ndị na-ere ọgwụ
Onye na-ahụ maka hypoglycemic bụ insulin na-adị mkpụmkpụ.

Koodu ATX A10AB01.

Ngwongwo ogwu
Mlọ ọgwụ
Humulin ® Regular bụ insulin nke na - emegharị mmadụ anya. Isi ihe dị na insulin bụ nhazi nke metabolism metabolism. Na mgbakwunye, ọ nwere anabolic na mgbochi catabolic na anụ ahụ dị iche iche nke ahụ. Na akwara anụ ahụ, enwere mmụba nke ọdịnaya glycogen, abụba abụba, glycerol, mmụba nke njikọ protein na mmụba nke amino acid, mana n'otu oge ahụ enwere mbelata nke glycogenolysis, gluconeogenesis, ketogenesis, lipolysis, catabolism protein na ntọhapụ nke amino acid.
Humulin ® Regular bụ nhazi insulin na-adị mkpụmkpụ. Mmalite nke ị theụ ọgwụ ahụ bụ nkeji 30 mgbe nchịkwa gasịrị, mmetụta kachasị n'etiti awa 1 na 3, oge nke ime ihe ahụ bụ awa 5-7. Ọdịiche dị iche iche na arụ ọrụ insulin na-adabere n'ihe ndị dị ka dose, nhọrọ nke saịtị ịgba ahụ, mmega ahụ nke onye ọrịa, wdg.

Mlọ ọgwụ
Njuputa nke nnabata na mmalite nke mmetụta nke insulin na-adabere na saịtị injection (afọ, afọ, isi), dose (olu insulin insulin), mkpokọta nke insulin na ọgwụ, wdg Ọ na-ekesa na-agafe n’akpụ anụ ahụ, ọ banyeghịkwa n'ihe mgbochi placental na n'ime mmiri ara. Ọ bụ insulinase na-abụkarị imeju ya na akụrụ. Ọ bụ ya bụ akụrụ (30-80%).

Nhazi ọkwa nosological (ICD-10)

Usoro onunu ogwu na nhazi

S / c n'ubu, apata ụkwụ, aka ekpe ma ọ bụ afọ. A na-ahapụ nchịkwa intramuscular.

Ọ bụ dọkịta ga-ekpebi dose nke Humulin ® M3, ọ dabere na glucose dị n'ọbara. Na / na iwebata ọgwụ Humulin M3 bụ contraindicated.

Okpomọkụ dị iche iche nke ọgwụ a na-elekọta kwesịrị ịdị na n ụlọ ahụ. Ekwesịrị ịgbanye saịtị ndị injection ahụ ka ejiri otu ebe ahụ karịa ihe dịka otu ọnwa. Site na nchịkwa insulin nke s / c, a ga-akpachara anya ịbanye na arịa ọbara. Mgbe ogwu ogbugba gasịrị, ekwesighi ịhịa aka ntụtụ.

Ekwesịrị ịzụ ndị ọrịa ka esi eji ngwaọrụ nnabata insulin ya mee ihe nke ọma.

Humulin ® M3 bụ ngwakọta emebere nke nwere otu ọdịnaya nke Humulin ® Regular na Humulin ® NPH, akwadoro iji gbochie mkpa ịgwakọta insulin site n'aka ndị ọrịa n'onwe ha. Usoro nchịkwa insulin dị iche iche.

Nkwadebe maka okwu mmeghe

Maka nkwadebe Humulin ® M3 na vials. Ozugbo ejiri ya, a ga-efegharị vials nke Humulin ® M3 n'etiti etiti n'ọbụ aka ọtụtụ oge ruo mgbe a ga-enweta insulin ahụ kpamkpam ruo mgbe ọ ghọrọ akwa mmiri ma ọ bụ mmiri ara ehi edo edo. Ikwanye ike, dika nke a nwere ike ibute ụfụfụ, nke nwere ike igbochi ọgwụ kwesịrị ekwesị. Ejila insulin ma ọ bụrụ na o nwere flakes mgbe agwakọtara ma ọ bụ irighiri ihe na-acha ọcha siri ike na-agbado na okpuru ma ọ bụ mgbidi nke vial, na-ekepụta mmetụta nke usoro ikuku. Jiri sirinji insulin nke kwekọrọ na mkpokọta insulin.

Maka nkwadebe Humulin ® M3 na katrized. Ngwa ngwa iji, Humulin should M3 kwesịrị ka akpọrepu n'etiti ọbụ aka ugboro iri wee maa jijiji, na-atụgharị 180 Celsius ugboro iri ruo mgbe insulin gagharigharịrị ruo mgbe ọ ghọrọ akwa mmiri ma ọ bụ mmiri ara edo edo. Ikwanye ike, dika nke a nwere ike ibute ụfụfụ, nke nwere ike igbochi ọgwụ kwesịrị ekwesị. N'ime katriiki ọ bụla, nwere obere bọl karama nke na-eme ka ịgwakọta insulin. Ejila insulin ma ọ bụrụ na enwere flakes mgbe agwakọta. Ngwaọrụ nke katalọgụ anaghị ekwe ka agwakọta ihe ndị dị n’ime ya na ihe ndị ọzọ dị na katriiki n’onwe ya. Edeghị Cart Cartges. Tupu ntụtụ ahụ, ọ dị mkpa iji aka gị mata ntụziaka nke onye nrụpụta maka iji mkpụrụ edemede sirinji maka inye insulin.

Maka Humulin ® M3 na QuickPen ™ Syringe Pen. Tupu ntụtụ, ị ga-agụ QuickPen ™ Syringe Pen Instructions maka Jiri.

Ntinye Pen Sydee QuickPen.

QuickPen ™ Syringe Pen dị mfe iji. Ọ bụ ngwaọrụ maka inye insulin (“insulin pen”) nke nwere 3 ml (300 PIECES) nke ịkwadebe insulin na-arụ ọrụ nke 100 IU / ml. You nwere ike tinye site na nha 1 insulin 60 na ntụtụ. You nwere ike ị dozie dose ahụ na izi ezi nke otu mpaghara. Ọ bụrụ na etinyere ọtụtụ nkeji, enwere ike idozi dose ahụ n’enweghi insulin. A na-atụ aro QuickPen ™ Syringe Pen maka iji agịga mmepụta Becton, Dickinson na Companylọ Ọrụ (BD) maka ogwe eji ogwu Tupu iji mkpịsị sirinji, gbaa mbọ hụ na agịga ahụ dị n’akpa sirinji.

N’ọdịnihu, aga-eso iwu ndị a.

1. Soro iwu asepsis na ọgwụ antiseptics nke dọkịta gị tụrụ aro ya.

3. Họrọ ebe igba ogwu.

4. Ghichaa anụ ahụ na ntụtụ.

5. Ebe saịtị ịgba ọzọ ka ị ga-eji otu ebe ahụ ihe karịa otu ugboro n'ọnwa.

QuickPen ™ Syringe Pen Nkwadebe na Okwu Mmalite

1. Mepụta okpu nke mkpụrụ sirinji ka iwepu ya. Emegharịgharị okpu. Ewepula akara sitere na sirinji pen. Gbaa mbọ hụ na enyocha insulin maka ụdị insulin, ụbọchị ngafe, ọdịdị. Jiri nwayọ tụgharịa sirinji ugboro iri n'etiti nkwụ aka ma tụgharịa ugboro iri.

2. Were agịga ọhụrụ. Wepu ihe mmado mpempe akwụkwọ n’elu isi mpụta agịga. Jiri akwa swab hichaa diski roba na njedebe nke ihe nkwakọ ngwaahịa ahụ. Gbakwunye agịga dị na okpu ahụ, na mberede, na pen sirinji. Ghaa agịga ahụ ruo mgbe jikọtara ya nke ọma.

3. Wepu okpu dị na mpụta. Atụfula ya. Wepu okpu nke agịga ma tụfuo ya.

4. Lelee QuickPen ™ Syringe Pen maka insulin. Oge ọ bụla ị ga-elele nnabata nke insulin. Nyochapụta nnyefe insulin site na sirinji mkpirisi ka a ga-eme tupu ntụtụ ọ bụla ruo mgbe nnwale nke insulin pụtara iji jide n'aka na mkpịsị sirinji dị njikere maka dose ahụ.

Ọ bụrụ n ’enyochaghị insulin tupu nsogbu ahụ apụta, ị nwere ike nweta ntakịrị insulin ma ọ bụ nke ukwuu.

5. Mezie anụ ahụ site na ịdọpụta ya ma ọ bụ chịkọta ya na nnukwu ogige. Tinye ntụtụ skị site na iji usoro ntụtụ dọkịta gị gwara gị. Tinye mkpịsị aka gị na bọtịnụ ọgwụ wee pịa sie ike ruo mgbe ọ kwụsịrị kpam kpam. Enterbanye njupụta zuru ezu, jide bọtịnụ dose ma jiri nwayọ gụọ 5.

6. Wepu agịga ahụ ma jiri nwayọọ sụchaa ebe ịgba ọgwụ ntụtụ ahụ ruo ọtụtụ sekọnd. Etekwala ebe a na-agba ntụtụ. Ọ bụrụ na insulin si na agịga dapụta, o yikarịrị ka onye ọrịa ahụ ejideghị agịga ahụ n'okpuru akpụkpọ ahụ ogologo oge. Ọnụnọ nke insulin ins na n'ọnụ nke agịga bụ ihe dị otú o kwesịrị, ọ gaghị emetụta dose ahụ.

7. Iji okpu agịga, wepụpụ agịga ma kpofu ya.

A na-ebipụta ọnụọgụ dị na windo ngosipụta nke ọnụọgụ dịka ọnụọgụ, ọnụọgụ dị iche iche dịka ahịrị kwụ ọtọ n'etiti nọmba.

Ọ bụrụ na usoro achọrọ maka nchịkwa karịrị ọnụọgụ nkeji fọdụrụ na plọg, ị nwere ike tinye insulin nke fọdụrụnụ wee jiri pen ọhụrụ mezue nchịkwa nke ọgwụ achọrọ, ma ọ bụ tinye pensụ ọhụrụ edee.

Agbalịla ịgba ọgwụ insulin site na ịgbagharị bọtịnụ dose. Onye ọrịa ahụ agaghị enweta insulin ma ọ bụrụ na ọ tụgharịa bọtịnụ ọ̀tụ̀tụ̀. Mustkwesịrị pịa bọtịnụ dose ahụ na ahịrị abụọ ka ị nweta insulin.

Agbalịla ịgbanwe ọgwụ insulin n'oge a na-agba ya.

Rịba ama Mkpịsị sirinji agaghị ekwe ka onye ọrịa wepụta ọgwụ insulin karịa ngafe nke mkpụrụ nkeji na-apụ na sirinji. Ọ bụrụ n ’ijide n’aka na a na-enye ọgwụ zuru ezu, ịgaghị abanye na nke ọzọ. Ọ dị mkpa iji wepu agịga mgbe ọ bụla ịgba. Kwesịrị ịgụ ma soro ntuziaka dị na ntuziaka maka ojiji nke ọgwụ. Ọ dị mkpa inyocha akara dị na pen sirinji tupu ntụtụ ọ bụla, iji jide n'aka na ụbọchị ngafe nke ọgwụ ahụ agwụbeghị ma onye ọrịa ahụ ejiri ụdị insulin ahụ ziri ezi, ewepụla aha ahụ na pen sirinji.

Agba nke QuickPick ™ syringe pen pen na-ekwekọ na agba nke warara na sirinji mkpịsị edemede ma dabere n'ụdị insulin. N'ime akwụkwọ ntuziaka a, a na-eji bọtịnụ dose ahụ pụọ. Agba agba aja aja nke QuickPen ™ sirinji ahu na-egosi na achọrọ iji ya jiri ngwaahịa Humulin ®.

Nchekwa na mkpofu

Agaghị enwe ike iji mkpịsị akwụkwọ ahụ ma ọ bụrụ na ọ nọghị na friji karịa oge akọwapụtara na ntuziaka maka ojiji.

Edobela mkpịsị edemede ya na agịga ahụ. Ọ bụrụ na agịga agịga, insulin nwere ike wepụta site na mkpịsị akwụkwọ ya, ma ọ bụ insulin nwere ike kpọnye ya na agịga ahụ, si otú ahụ na-emechi agịga, ma ọ bụ afụ ikuku nwere ike ịmalite n'ime katriiki.

A ga-echekwa mkpịsị mkpụrụ sirinji na-adịghị arụ ọrụ na friji n'oge okpomọkụ 2 ruo 8 Celsius. Ejila pen sirinji ma ọ bụrụ na agbajụọla.

Ekwesịrị ịchekwa mkpụrụ sirinji eji eme ihe ugbu a na ụlọ okpomọkụ, ebe echekwara site na ikpo ọkụ na ọkụ, site na ụmụaka agaghị eru.

Tụfuo agịga eji eme ihe na kọmpụta, igbe ndị yiri (dịka ọmụmaatụ maka ihe ndị na-emebi ihe ma ọ bụ ihe mkpofu), ma ọ bụ ndị ọrụ nlekọta ahụike tụrụ aro ya.

Tụfuo mkpịsị ahụ ejiri sirinji na-enweghị agịga dabere na ndụmọdụ ndị dibịa na-aga dị ka usoro nlekọta mkpofu mpaghara dị.

Ejikwala ihe ndochiri eju.

Mpempe mwepụta

Nkwụsịtụ maka nchịkwa subcutaneous, 100 IU / ml. 10 ml nke ọgwụ na-anọpụ iche iko vials. 1 fl. tinye ya na ngwugwu kaadiboodu.

3 ml ọ bụla na katalọgụ iko na-anọpụ iche. A na-etinye katriiki 5 na chaplet. 1 bl. etinye ha n’ime igbe kaadiodu ma obu itinye kaadiboodu n’ime mkpirisi IMPo ring syringe. A na-etinye mkpịsị mkpụrụ sirinji n'ime kaadiboodu.

Emeputa

Mepụtara: Eli Lilly na Companylọ Ọrụ, USA. Lilly Corporate Center, Indianapolis, Indiana 46285, USA.

Ihe ngwugwu: ZAO "ORTAT", 157092, Russia, Kostroma mpaghara, mpaghara Susaninsky, s. Northern, microdistrict. Kharitonovo.

Cartridges, QuickPen ens Syringe pen , nke Lilly France, France mepụtara. Mpaghara Industrialiel, 2 ru Colonel Lilly, 67640 Fegersheim, France.

Ihe ngwugwu: ZAO "ORTAT", 157092, Russia, Kostroma mpaghara, mpaghara Susaninsky, s. Northern, microdistrict. Kharitonovo.

Lilly Pharma LLC bụ onye mbubata naanị nke Humulin ® M3 na Russian Federation

Omume ọgwụ

Nnukwu insulin nke mmadụ na-eme n’onwe ya. Ọ bụ nkwadebe insulin na-ajụ ajụ.
Isi mmetụta nke ọgwụ bụ iwu nke glucose metabolism. Na mgbakwunye, o nwere mmetụta anabolic. Na akwara na akwara ndị ọzọ (ewezuga ụbụrụ), insulin na - ebute ọsịsọ glucose na amino acid na - eme ngwa ngwa intracellular. Insulin na - akwalite ntụgharị nke glucose na glycogen na imeju, na - egbochi gluconeogenesis ma na - akpali ntụgharị nke oke glucose na abụba.

Nsonaazụ

- Nsonaazụ metụtara isi mmetụta nke ọgwụ: hypoglycemia.
- Nnukwu hypoglycemia nwere ike ibute ọnwụ na (n'ọnọdụ ụfọdụ) ọnwụ.
- Mmeghachi omume nfụkasị: mmeghachi omume nfụkasị mpaghara nwere ike - hyperemia, ọzịza ma ọ bụ itching na saịtị ịgba ntụtụ (na - akwụsịkarị n'ime oge ọtụtụ ụbọchị ruo ọtụtụ izu), mmeghachi omume nfụkasị usoro (na - erughị oge, mana ọ ka njọ) - itching juputara, mkpụmkpụ ume, mkpụmkpụ ume iku ume, mbelata ọbara mgbali elu, obi ịba ụba, ịsụsọ. Ọnọdụ siri ike nke mmeghachi omume nfụkasị systemic nwere ike igbu mmadụ.
- Ndị ọzọ: ohere dị obere nke lipodystrophy dị obere.

Mpempe usoro onunu ogwu

Nkwụsịtụ maka ntụtụ 100 IU / ml

Otu mil nke nkwusioru nwere

ike - insulin mmadụ (DNA - recombinant) 100 IU,

ndị mgbe ochie: metacresol distilled, glycerin, phenol, sulfate protamine, sodium hydrogen phosphate heptahydrate, zinc oxide (na usoro nke Zn ++ zinc), hydrochloric acid 10% iji dozie pH, sodium hydroxide 10% iji dozie pH, mmiri maka injection.

Nkwụsị na-acha ọcha, nke, mgbe ọ na-eguzo ọtọ, na-ekpughere ya n'ụzọ doro anya, enweghị agba ma ọ bụ ihe fọrọ nke nta ka ọ bụrụ nke na-enweghị ọ andụ na mkpachapụ ọcha. A na - eji nwayọ nwayọ were weghachite ihe omume.

Ngwongwo ogwu

Mlọ ọgwụ

Humulin® M3 bụ ihe eji eme insulin. Mmalite nke ị theụ ọgwụ ahụ bụ nkeji 30 mgbe nchịkwa gasịrị, nsonaazụ kachasị n'etiti 1 na 8.5 awa, ogologo oge nke ihe ahụ bụ awa 14-15.

A na - egosipụta profaịlụ arụmọrụ (glucose uptake curve) mgbe nchịkwa subcutaneous dị ka akara uko na ọnụ ọgụgụ dị n'okpuru. Ọdịiche dị iche iche na arụ ọrụ insulin na-adabere n'ihe ndị dị ka dose, nhọrọ nke saịtị ịgba ahụ, mmega ahụ nke onye ọrịa, wdg.

Ọrụ insulin

Oge (awa)

Mlọ ọgwụ

Humulin M3 bụ insulin mmadụ na-ejikọghachi na ya. Ọ bụ nkwusioru nke okpukpu abụọ maka injection (30% Humulin Х Regular na 70% Humulin NPH).

Isi ihe dị na insulin bụ nhazi nke metabolism metabolism.

Na mgbakwunye, ọ nwere anabolic na mgbochi catabolic na anụ ahụ dị iche iche. Na akwara anụ ahụ, enwere mmụba nke ọdịnaya glycogen, abụba abụba, glycerol, mmụba nke njikọ protein na mmụba nke amino acid, mana n'otu oge ahụ enwere mbelata nke glycogenolysis, gluconeogenesis, ketogenesis, lipolysis, catabolism protein na ntọhapụ nke amino acid.