Lantus SoloStar

Ọgwụ Lantus SoloStar (Lantus solostar) sitere na analogue nke insulin mmadụ, nke nwere solubility dị ala na gburugburu na-anọpụ iche. N'ihi mpaghara acidic nke ihe ngwọta Lantus SoloStar insulin glargine na-agbaze kpamkpam, mana site na nchịkwa subcutaneous, a na-ewepụ acid na microprecipitates n'ihi mbelata nke solubility, site na nke nta nke nta wepụta insulin. Ya mere, mmụba na-abawanye ụba na ọkwa plasma nke insulin na-enweghị ọnụ ọnụ dị nkọ na mmetụta ogologo oge nke ọgwụ Lantus SoloStar na-enweta.
Na insulin glargine na insulin nke mmadụ, nkwonkwo nkwonkwo nke ndị na-anabata insulin na-enwekwa. Profaịlụ na ike nke insulin glargine dị ka nke insulin mmadụ.

Ọgwụ na-achịkwa metabolism metabolism, ọkachasị, na-ebelata oke glucose plasma site na ibelata mmepụta ya na imeju na ịbawanye ụba glucose site na akwara akụkụ (tumadi akwara na adipose anụ ahụ). Insulin na - egbochi proteinotosis na lipolysis na adipocytes, ma na - akwalite njikọ protein.
Ihe insulin glargine, na-achịkwa subcutaneously, na-ebido nwayọ karịa na iwebata NPH nke insulin, a na-eji ya eme ihe ogologo oge na enweghị ụkpụrụ kachasị. N'ụzọ dị otú a ọgwụ Lantus SoloStar enwere ike iji 1 oge kwa ụbọchị. Buru n’uche na ịdị n’otu insulin nwere ike ịdị iche iche n’otu onye (yana imega ahụ ọ na-aba ụba, mmụba ma ọ bụ mgbadalata, wdg).

Na nyocha nke ụlọ ọgwụ mepere emepe, emere ka ọ pụta ìhè na insulin glargine anaghị eme ka ọrịa uto na-arịa ọrịa shuga (ọria na-egosi insulin glargine na insulin nke mmadụ adịghị iche).
Mgbe ị na-eji ọgwụ ọjọọ eme ihe Lantus SoloStar enwere ike itinye insulin n'ime mkpụrụ ụbọchị n’ụbọchị 2-4.
Insulin glargine bụ metabolized n'ime ahụ wee mepụta metabolites abụọ na-arụ ọrụ, M1 na M2. Ọrụ dị mkpa n'ịhụta nsonaazụ nke ọgwụ Lantus SoloStar bụ nke metabolite M1 na-arụ, na plasma ka a na-ekpebi insulin glargine na metabolite M2 na-agbanwegharị na obere.
Enweghị ọdịiche dị mkpa na arụmọrụ yana nchekwa nke insulin insulin na ndị ọrịa nke otu dị iche iche na ọnụọgụ ndị ọrịa n'ozuzu ha.

Ihe ngosi maka ojiji:
Lantus SoloStar Ejiri maka ọgwụgwọ nke ndị ọrịa karịrị afọ 6 na ọrịa shuga mellitus na-akpata insulin.

Usezọ iji:
Lantus SoloStar ezubere maka nchịkwa subcutaneous. A na-atụ aro ịmebata ọgwụ Lantus SoloStar n'otu oge nke ụbọchị. Isgwọ ọgwụ Lantus SoloStar ka dọkịta họrọ n’otu n’otu. Ekwesiri iburu n'uche na a na-egosipụta usoro ị ofụ ọgwụ ahụ na nkeji ihe dị iche iche nke enweghị ike iji ya tụnyere nkeji ọrụ nke insulins ndị ọzọ.
Anabatara iji ọgwụ a Lantus SoloStar n'ime ndị ọrịa nwere ụdị ọrịa shuga mellitus nke 2 yana ọnụ ọgụgụ ndị na-arịa ọrịa hypoglycemic.

Na-agbanwe site na insulin ọzọ ka Lantus SoloStar:
Mgbe ị na-atụgharị na Lantus SoloStar site na ndị ọzọ na-ajụ ma ọ bụ na-eme ogologo oge, enwere ike ịdị mkpa maka mmezi nke ọgwụ kwa ụbọchị nke insulin basal, yana mgbanwe mgbanwe na usoro onyonyo nke iwere ndị ọzọ hypoglycemic. Iji belata ihe ize ndụ nke hypoglycemia n'oge mgbanwe nke Lantus SoloStar n'ime izu ole na ole mbụ, a na-atụ aro ka iwetulata ọgwụ insulin na ntụzi kwesịrị ekwesị nke insulin, nke ewepụtara n'ihe metụtara oriri nri. Izu ole na ole mgbe ọgwụ Lantus SoloStar kwụsịrị ọgwụ, a na-emeghari insulin nke insal insal na insulins na-adị obere oge.
N'ime ndị ọrịa na-anata insulin ogologo oge, ọdịdị nke ọgwụ mgbochi insulin na mbelata mmeghachi omume na nchịkwa nke ọgwụ Lantus SoloStar ga-ekwe omume.
Mgbe ị na-agbanwe site na insulin gaa na nke ọzọ, yana n'oge ndozi dose, ekwesịrị ilebara ọkwa glucose plasma anya nke ọma.

Iwebata ọgwụ ọjọọ Lantus SoloStar:
Ejiri ọgwụ a na subcutaneously na deltoid, apata ma ọ bụ mpaghara abdominal. A na-atụ aro ịgbanwe saịtị ntụtụ ahụ n'etiti mpaghara ndị a na-anabata na ntụtụ ọgwụ ọ bụla Lantus SoloStar. Amachibidoro ịhazi Lantus SoloStar intravenively (n'ihi ihe ize ndụ nke ịdoụbiga mmanya ókè na mmepe nke hypoglycemia siri ike).
Amachibidoro ịgwakọta insulin glargine na ọgwụ ndị ọzọ.
Ozugbo tupu insulin glargine nchịkwa, wepu ntụ ikuku site na akpa ma mee nnwale nchekwa. Ekwesịrị iji agịga ọ bụla mee ihe ọ bụla, nke a na-etinye na mkpịsị mkpụrụ ngwa ngwa tupu iji ọgwụ ahụ.

Iji Syringe Pen Lantus SoloStar:
Tupu ojiji, ịkwesịrị iji nlezianya nyochaa katriel nke mkpụrụ sirinji, ị nwere ike iji naanị ihe doro anya na-enweghị irighiri mmiri. N'ọnọdụ nke ịkọwapụta, igwe ojii, ma ọ bụ mgbanwe agba nke ihe ngwọta, amachibidoro iji ọgwụ ahụ. Should ga-ewepụrịrị mkpụrụ sirinji ọ bụla. Ọ bụrụ na sirinji mebiri emebi, ị ga-ewere mkpịsị mkpụrụ ọhụrụ wee tufuo nke mebiri emebi.

Tupu ntụtụ ọ bụla, ule nchekwa ga-eme:
1. Lelee labeelu insulin na ọdịdị nke ihe ngwọta.
2. Wepu okpu nke sirinji tinye ya agịga ọhụrụ (a ga-ebipụta agịga ozugbo tupu ịgọnye ya, amachibidoro itinye ya agịga n'otu akụkụ).
3. Tụọ dose nke nkeji abụọ (ọ bụrụ na ejibeghị mkpụrụ sirinji 8) tinye mkpịsị ahụ na mkpịsị ahụ, jiri nwayọ pịa krieti ahụ, pịa bọtịnụ ntinye ahụ ruo mgbe ịchọrọ maka ọdịdị nke insulin inspe na n'ọnụ agịga ahụ.
4. Ọ bụrụ na ọ dị mkpa, a na-enyocha ule nchekwa ọtụtụ oge ruo mgbe ihe ngwọta pụtara n'ọnụ ọnụ agịga. Ọ bụrụ na mgbe ọtụtụ nnwale insulin apụtaghị, dochie agịga. Ọ bụrụ na usoro ndị a enyereghị aka, mkpụrụ sirinji nwere nkwarụ, ejila ya.

Amachibidoro ịnyefe mkpụrụ edemede sịnịma ndị ọzọ.
A na-atụ aro mgbe niile ka ịnwe nha mkpụrụ edemede sirinji Lantus SoloStar bụrụ nke mmebi ma ọ bụ ọnwụ nke mkpụrụ edemede sirinji eji.
Ọ bụrụ na echekwara mkpịsị ahụ n'ime friji, a ga-ewepụ ya awa 1-2 tupu ntụtụ ya ka ọ dị n ’ihe ga-eme ka okpomoku ahụ kporo ọkụ.
E kwesịrị iji mkpịsị sirinji kpuchie unyi na ájá, ị nwere ike iji akwa dị ọcha kpochaa mpụta sirinji.

Amachibidoro ịsa mkpịsị ahụ mkpị bụ Lantus SoloStar.

Dose nhọrọ:
Lantus SoloStar na-enye gị ohere ịtọ ọgwụ ahụ site na 1 nkeji gaa na nkeji 80 na mgbakwunye nke 1 unit. Ọ bụrụ na ọ dị mkpa, pịnye ọgwụ ruru ihe karịrị iri asatọ iji gwọọ ọtụtụ inpa.
Gbaa mbọ hụ na mgbe ule nchekwa ahụ gasịrị, windo dosing na-egosi “0”, họrọ usoro achọrọ site na ịtụgharị onye na-ahọrọ dosing. Ka ịhọrọ ọgwụ ịchọrọ, fanye agịga ahụ n’akpụkpọ ahụ ma pịa bọtịnụ ntinye ahụ niile. Ka emechara ọgwụ a, uru “0” kwesịrị ka edobe na mpio dosing. Vinghapụ agịga ahụ n’akpụkpọ anụ ahụ, gụọ 10 ma dọpụ agịị ahụ n’akpụkpọ ahụ.
Wepu agịga ahụ site na sirinji ma wepụ ya, jiri okpu mechie sirinji ma chekwaa ruo mgbe ọzọ.

Mmetụta ọghọm:
Mgbe ị na-eji ọgwụ ọjọọ eme ihe Lantus SoloStar n'ime ndị ọrịa, mmepe nke hypoglycemia ga-ekwe omume, n'ihi nnabata nke insulin dị elu na mgbanwe nri, mmega ahụ na mmepe / mkpochapụ ọnọdụ ndị na-akpata nchekasị. Nnukwu hypoglycemia nwere ike ibute mmepe nke nsogbu akwara ozi ma mekwaa ihe egwu na ndụ onye ọrịa.
Na mgbakwunye, mgbe ị na-eji ọgwụ ahụ Lantus SoloStar n'oge nnwale nke ụlọ ọgwụ na ndị ọrịa, ọ rụpụtara nsonaazụ ndị na-esonụ:
Site na usoro ụjọ na akwara anụ ahụ: dysgeusia, retinopathy, belata acuity visual. Nnukwu ịba ọcha n'anya nwere ike iduga mmepe nke ọhụụ nwa oge na ndị ọrịa nwere ọrịa retinopathy na-aba ụba.

N'akụkụ anụ ahụ na anụ ahụ dị n'okpuru ala: lipodystrophy, lipoatrophy, lipohypertrophy.
Mmeghachi omume nfụkasị ahụ: mmeghachi omume nfụkasị akpụkpọ anụ ahụ, bronchospasm, ụjọ anaphylactic, edere nke Quincke.
Mmetụta mpaghara: hyperemia, edema, soreness na mmeghachi omume mbufụt na ntụtụ ebe Lantus SoloStar.
Ndị ọzọ: mgbu mgbu, njigide sodium n’ahụ.
Profaịlụ nchekwa ọgwụ Lantus SoloStar n'ime ụmụaka karịrị 6 afọ na ndị okenye yiri.

Contraindications:
Lantus SoloStar enyela ndị ọrịa ọrịa amatalarị insulin glargine ma ọ bụ ihe ndị ọzọ mejupụtara ọgwụ ahụ.
Ejighi Lantus SoloStar gwọọ ndị ọrịa nwere nsogbu gbasara akụrụ na nnukwu ịba ọcha n'anya.
Na omume ụmụaka, ọgwụ Lantus SoloStar E jiri ya mee ihe maka ọgwụgwọ ụmụaka kariri afọ isii.
Lantus SoloStar ọ bụghị ọgwụ ịhọrọ maka ọgwụgwọ nke ketoacidosis mamịrị.
N'ime ndị ọrịa agadi, yana ndị ọrịa nwere akụrụ gbasara akwara na hepatic, ọgwụ insulin nwere ike belata, ekwesịrị ịdebe ndị ọrịa dị otú ahụ Lantus SoloStar site na iji nlezianya (na-elele ọkwa glucose plasma mgbe niile).
Ekwesịrị ịkpachara anya mgbe ị na-ahọrọ usoro ọgwụgwọ maka ndị ọrịa nwere ọrịa hypoglycemia nwere ike inwe nsonaazụ dị egwu.

Ọ kachasị, na iji nlezianya, Edere Lantus SoloStar maka ndị ọrịa nwere ọrịa ụbụrụ ma ọ bụ akwara ụbụrụ na retinopathy proliferative.

Ekwesịrị ịkpachara anya mgbe a na-edepụta Lantus SoloStar nye ndị ọrịa ebe mgbaàmà hypoglycemia dị mkpirikpi ma ọ bụ nke dị nro, gụnyere ndị ọrịa nwere mmelite na ntụgharị glycemic, ogologo akụkọ banyere ọrịa shuga, ọrịa akwara, ọrịa uche, mmepe nke hypoglycemia, yana ndị ọrịa agadi na ndị ọrịa, na-aga site na insulin anụmanụ rue mmadụ.
Ekwesịrị iji nlezianya mee ihe mgbe ị na-ede ọgwụ ahụ. Lantus SoloStar ndị ọrịa nwere ebumnuche ịmalite hypoglycemia. Ihe ize ndụ nke ịmalite hypoglycemia na-abawanye na mgbanwe na saịtị nke nchịkwa insulin, mmụba nke nnwale insulin (gụnyere mkpochapụ ọnọdụ nrụgide), ịba ụba nke anụ ahụ, nri na-adịghị mma, ọgbụgbọ, afọ ọsịsa, mmanya na-egbu egbu, ọrịa na-enweghị atụ nke usoro endocrine, na iji ụfọdụ ọgwụ ( lee Mmekorita Ya na Ogwu Ozo).
Ndị ọrịa nwere ọrịa shuga kwesịrị ịkpachara anya jikwaa usoro ndị nwere ike ịdobe nsogbu, mmepe nke hypoglycemia nwere ike ibute ọgbụgba na mbelata ịta.

Ime
Enweghị data ụlọ ọgwụ banyere iji ọgwụ ahụ Lantus SoloStar n’ime ụmụ nwanyị dị ime. N'ime ọmụmụ anụmanụ, ekpughere na-enweghị teratogenic, mutagenic na mmetụta nke ẹmbrayo insulin glargine, yana mmetụta ọjọọ ya na ime na ịmụ nwa. Ọ bụrụ na ọ dị mkpa, enwere ike inye Lantus SoloStar ọgwụ maka ụmụ nwanyị dị ime. Ekwesịrị iji nlezianya nyochaa ọkwa glucose dị na ụmụ nwanyị dị ime, na-agbanwe mgbanwe insulin chọrọ. N'ime oge izizi, mkpa insulin nwere ike belata, na nke abụọ na nke atọ na-achọ ịrị elu.

Ozugbo amụrụ nwa, mkpa insulin na-ebelata nke ukwuu ma enwere ihe ize ndụ nke hypoglycemia.

N'oge a na-enye nwa ara, ọgwụ Lantus SoloStar enwere ike iji ya na nlegide na-aga n'ihu nke ọkwa glucose plasma. Enweghị data banyere nbanye insulin glargine n'ime mmiri ara, mana na nri diges, insulin glargine kewara amino acid ma ghara imerụ ụmụ amụrụ ọhụrụ ndị nne ya na-anata ọgwụgwọ na Lantus SoloStar.

Mmekọrịta na ọgwụ ndị ọzọ:
Ọgwụ nke ọgwụ Lantus SoloStar ị nwere ike ịdị iche na ojiji ọgwụ ndị ọzọ jikọtara, ọkachasị:
Ndị na-ahụ maka ọgwụ antidiabetic, angiotensin na-agbanwe enzyme inhibitors, monoamine oxidase inhibitors, salicylates, sulfanilamides, fluoxetine, propoxyphene, pentoxifylline, nnupụisi na ọgwụ na-egbochi mmetụta insulin glargine mgbe ejikọtara ọnụ.
Corticosteroids, diuretics, danazole, glucagon, diazoxide, estrogens na progestins, isoniazid, sympathomimetics, somatropin, protein na-egbochi, homonụ thyroid na antipsychotics belata mmetụta hypoglycemic nke ọgwụ Lantus SoloStar.
Ngwakọta lithium, clonidine, pentamidine, mmanya etyl na mgbochi beta-adrenoreceptor nwere ike abụọ ma belata mmetụta hypoglycemic nke ọgwụ Lantus SoloStar.
Lantus SoloStar na-ebelata ogo mmetụta nke clonidine, reserpine, guanethidine na beta-adrenergic blockers.

Dodoụbiga ya ókè
N'ihi ịba ụba insulin nke gabigara ókè, ndị ọrịa na-amalite hypoglycemia nke ụdị nsogbu dịgasị iche iche. Site na nnukwu hypoglycemia, mmepe nke ọdụdọ, coma na nkwarụ akwara ga-ekwe omume.
Ihe kpatara ịdoụbiga ọgwụ ókè Lantus SoloStar enwere ike ịgbanwe mgbanwe dosing (nchịkwa nke nnukwu ọgwụ), nri iri nri, ịba ụba nke arụ ọrụ, vomiting na afọ ọsịsa, ọrịa na-ebelata mkpa insulin (tinyere mkpịsị akwara na-arụ ọrụ na ịba ọcha n'anya, hypofunction of the pituitary gland, adrenal cortex or thyroid gland), mgbanwe na ọnọdụ iwebata ọgwụ Lantus SoloStar.

A na-agbazi ụdị hypoglycemia dị nro site na ọnụ nke carbohydrates (ịkwesịrị inye onye ọrịa carbohydrates na ogologo oge ma nyochaa ọnọdụ ya, ebe ọgwụ Lantus SoloStar nwere ogologo oge).
Na nnukwu hypoglycemia (gụnyere ihe ngosipụta akwara ozi), a na-egosi nchịkwa glucagon (subcutaneously ma ọ bụ intramuscularly) ma ọ bụ nchịkwa intravenous nke usoro glucose dị ukwuu.
Ekwesịrị inyocha ọnọdụ onye ọrịa ahụ ruo elekere 24, ebe ọ bụ na ọrịa nke hypoglycemia nwere ike ịmaliteghachi mgbe ịkwụsị ọgụ nke hypoglycemia ma melite ọnọdụ onye ọrịa.

Mwepụta weputara:
Ngwọta maka injections Lantus SoloStar 3 ml na katrized, ejiri hermetically tinye n’ime mkpịsị mkpụrụ sirinji, tinye mkpịsị mkpụrụ 5 na-enweghị agịga n’ime igbe kaadi.

Ọnọdụ nchekwa:
Lantus SoloStar ekwesiri ịchekwa ihe na-erughị afọ 3 mgbe emechara ya n'ime ụlọ ebe edobere ọkwa okpomọkụ si 2 ruo 8 Celsius. Debe mkpịsị ọrịị ka ụmụaka ghara iru. Amachibidoro ịnwe ngwụcha Lantus SoloStar.
Mgbe ojiji nke mbụ, enwere ike iji mkpịsị sirinji mee ihe ọ bụla karịa ụbọchị 28. Mgbe ịmalite ojiji, ekwesịrị ịchekwa mkpụrụ sirinji n'ime ụlọ nke nwere temprechọ nke okpukpu 15 ruo 25 Celsius.

Ngwakọta:
1 ml osisa nye ogwu ogwu Lantus SoloStar nwere:
Insulin glargine - 3.6378 mg (nke ra ka 100 insulin glargine).
Ihe ndi ozo.