Diabefarm - ntụziaka maka ojiji

INWETA
maka iji ọgwụ eme ihe

Nọmba ndebanye:

Aha ahia: Diabefarm ®

International Nonproprietary Aha: gliclazide

Mpempe usoro onunu ogwu: mbadamba

Ngwakọta:
Otu mbadamba 1 nwere
Arụ Ọrụ: gliclazide 80 mg
Ndị e mere: lactose monohydrate (shuga mmiri ara ehi), povidone, magnesium stearate.

Nkọwa
Mbadamba ụcha ọcha ma ọ bụ nke nwere agba nchara na-acha ọcha na-adị cylindrical nwere ihe ize ndụ na-adị n'ọdịdị chamfer.

Ndị na-ere ọgwụ: ihe nnọchianya hypoglycemic maka nchịkwa nke ọnụ nke sulfonylurea otu nke ọgbọ nke abụọ

Koodu ATX: A10VB09

Omume ọgwụ
Mlọ ọgwụ
Glyclazide na-akpali mkpụrụ ndụ insulin site na mkpụrụ ndụ reat-pancreatic,, na-eme ka insulin-secretory mmetụta nke glucose dị, ma na-eme ka ahụ ngwa ngwa anụ ahụ dị elu na insulin. Na-akpali ọrụ nke enzymes intracellular - muscle glycogen synthetase. Na -ebe oge site na oge iri nri rue mmalite insulin insulin. Ọ na - eweghachi mmiri ọgbụgba mbụ nke insulin (n'adịghị ka ihe ndị ọzọ sitere na sulfonylurea, nke nwere mmetụta tumadi n'oge ọkwa nke abụọ nke nzuzo). Na-ebelata mmụba postprandial na glucose ọbara.
Na mgbakwunye na emetụta metabolism metabolism, ọ na - eme ka microcirculation dịkwuo mma: ọ na - ebelata platelet na nchịkọta, na - egbochi vaskụla permeability, na - egbochi mmepe nke microthrombosis na atherosclerosis, ma weghachite usoro nke physiological parietal fibrinolysis. Na -ebelata akwara vaskụla n’ọkpụkpụ adrenaline. Na-agbagha mmepe nke ọrịa mamịrị retinopathy na ọkwa ieproliferative. Site na nephropathy ọrịa mamịrị na iji ogologo oge, enwere mbelata dị ukwuu na proteinuria. Ọ naghị ebute mmụba n’arụ ahụ, n’ihi ọ nwere mmetụta kachasị ukwuu na mmalite nke insulin insulin ma ghara ibute hyperinsulinemia, na-enyere aka belata oke ahụ n'ahụ ndị ọrịa nwere nri kwesịrị ekwesị. Ọ nwere ihe anti-atherogenic, na-ebelata ịta nke cholesterol n'ime ọbara.
Mlọ ọgwụ
Mgbe nchịkwa ọnụ gasịrị, ọ na-etinye obi gị dum na eriri afọ. Idopu ihe n’ulo di elu. Mgbe nchịkwa ọnụ nke 80 mg, a na-enweta ntinye kachasị na ọbara (2.2-8 μg / ml) mgbe ihe dị ka awa anọ gasịrị, mgbe nchịkwa 40 mg, a na-enweta ntinye kachasị na ọbara (2-3 μg / ml) mgbe awa 2-3 gachara. ya na protin plasma - 85-97%, olu nkesa - 0.35 l / n'arọ. A na-atụnye ịta ahụhụ dị na ọbara mgbe ụbọchị abụọ gachara. A na-agakọ ya na imeju, imeju nke metabolites asatọ.
Ọnụ ọgụgụ nke metabolite bụ isi nke achọtara n'ọbara bụ 2-3% nke ngụkọta ọgwụ a takenụrụ, ọ nweghị mmetụta hypoglycemic, mana ọ na - eme ka microcirculation dịkwuo mma. Ọ bụ akụrụ na - 70% n'ụdị metabolites, erughị 1% n'ụdị agbanweghị, site na eriri afọ - 12% n'ụdị metabolites.
Nkeji ọkara bụ elekere asatọ ruo iri abụọ.

Ihe ngosi maka ojiji
Elldị shuga abụọ nke ọrịa mellitus dị na ndị okenye yana yana usoro nri na mmega ahụ na-arụ ọrụ nke oke na nke ikpeazụ anaghị arụ ọrụ.

Ihe ngbanwe
Hypersensitivity na ọgwụ, ụdị 1 mellitus diabetes, ọrịa ketoacidosis na-arịa ọrịa shuga, shuga shuga, shuga, hyperosmolar coma, nnukwu ịba ọcha n'anya na / ma ọ bụ akụrụ, nnukwu ịwa ahụ, oke ọkụ, mmerụ ahụ na ọnọdụ ndị ọzọ chọrọ ọgwụ insulin, mgbochi ime eriri afọ, paresis afọ, ọnọdụ jikọtara nri ịba nri, mmepe nke hypoglycemia (ọrịa na-efe efe), leukopenia, ịtụ ime, inye nwa, ụmụ ozrast 18 afọ.

Jiri nlezianya Edere (mkpa iji nlezianya nyochaa na ịhọrọ dose) maka ọrịa febrile, ị ,ụ mmanya na ọrịa thyroid (yana arụrụ ọrụ).

Jiri n'oge ime na lactation
Ọgwụ a na contraindicated n'oge ime na n'oge nri.
Mgbe ime dị ime, a ga-akwụsị ọgwụ ozugbo.

Usoro onunu ogwu na nhazi
Ọtọ ọgwụ a n’otu n’otu, dabere n’afọ onye ọrịa, ngosipụta nke ọrịa ahụ na ọkwa nke glucose ọbara na-ebu ọnụ na oge awa 2 gachara. Ọgwụ mbụ kwa ụbọchị bụ 80 mg, nkezi kwa ụbọchị bụ 160 mg, yana kacha ụbọchị kwa ụbọchị bụ 320 mg. A na-ewere Diabefarm ọnụ ugboro abụọ n'ụbọchị (n'ụtụtụ na n'anyasị) minit 30-60 tupu nri.

Mmetụta akụkụ
Hypoglycemia (n'ihe banyere mmebi nke usoro onunu ogwu na nri ezughi oke): isi ọwụwa, inwe ike ọgwụgwụ, agụụ, ọsụsọ, ike adịghị ike, oke iwe, nchekasị, ahụ erughị ala, mbelata nke ịta ahụhụ na oge na-egbu oge, ịda mba, ahụhụ anya, aphasia, mkpọtụ, ọgba aghara sensor, dizziness. , ọnwụ nke njide onwe onye, ​​nchekasị, ihe mgbu, ịda mba, ọnwụ nke iku ume, enweghị ume, bradycardia.
Mmeghachi omume nfụkasị ahụ: itching, urticaria, maculopapular rash.
Site na akụkụ ahụ dị na hemopoietic: anaemia, thrombocytopenia, leukopenia.
Site na nri digestive: dyspepsia (ọgbụgbọ, afọ ọsịsa, mmetụta nke ịda oke na epigastrium), anorexia - ogo ahụ na-ebelata mgbe ewere nri, ọrụ imeju na-arụ ọrụ (cholestatic jaundice, ụba ọrụ nke “transpore“ imeju ”).

Dodoụbiga ya ókè
Mgbaàmà: hypoglycemia ga-ekwe omume, ruo na mmepe nke hypoglycemic coma.
Ọgwụ: Ọ bụrụ na onye ọrịa ahụ amata ahụ, were carbohydrates (shuga) dị mfe n'ime, yana nsogbu nke mmụọ, a na-achịkwa ngwakọta dextrose (glucose) 40% n'ime ọbara, 1-2 mg nke glucagon intramuscularly. Mgbe ọ nwetasịrị onwe ya, a ga-enyerịrị onye ọrịa ahụ nri nwere nnukwu carbohydrates na-adị ngwa ngwa (iji zere ịmalite ịmalite hypoglycemia). Na ụbụrụ ụbụrụ, mannitol na dexamethasone.

Mmekọrịta na ọgwụ ndị ọzọ
Angiotensin-na-agbanwe enzyme inhibitors (captopril, enalapril), H2-histamine receptor blockers (cimetidine), ọgwụ antifungal (miconazole, fluconazole), ọgwụ mgbochi na-abụghị steroidal (phenylbutazoflubrate, indigo), na-egbochi mmetụta hypogabulasma (ethionamide), salicylates, coumarin anticoagulants, steroid anabolic, beta-blockers, cyclophosphamide, chloramphenicol, monoamine oxidase inhibitors, su fanilamidy ruo ogologo oge eme ihe, fenfluramine, fluoxetine, pentoxifylline, guanethidine, theophylline, ọgwụ ọjọọ na-egbochi tubular secretion, reserpine, bromocriptine, disopyramide, pyridoxine, allopurinol, ethanol na etanolsoderzhaschie preparations, nakwa dị ka ndị ọzọ hypoglycemic ọgwụ (acarbose, biguanides, insulin).
Weled the hypoglycemic effect of Diabefarma barbiturates, glucocorticosteroids, sympathomimetics (epinephrine, clonidine, ritodrine, salbutamol, terbutaline), phenytoin, ngwa na-egbochi calcium, ihe carbonic anhydrase inhibitors, thiazide azolezgele numgelege , diazoxide, isoniazid, morphine, glucagon, rifampicin, homonụ thyroid, nnu nke lithium, na oke ọnụọgụ - nicotinic acid, chlorpromazine, estrogens na ọgwụ mgbochi mgbochi nke nwere ha.
Mgbe gị na ethanol na-emekọ ihe, mmeghachi omume disulfiram ga-ekwe omume.
Diabefarm na - ebulite ohere nke ventricular extrasystole mgbe ị na - ewere glycosides cardiac.
Beta-blockers, clonidine, reserpine, guanethidine nwere ike kpuchie ngosipụta nke hypoglycemia.
Ọgwụ ndị na-egbochi hematopoiesis ụmị ọkpụkpụ na-abawanye ihe ize ndụ nke myelosuppression.

Ntụziaka pụrụ iche
A na-eme ọgwụgwọ Diabefarm na nri nwere obere kalori, carb dị ala. Ọ dị mkpa ileba ọdịnaya glucose anya n'ime ọbara mgbe afọ na-enweghị nri na mgbe ị risịrị nri.
N'ihe banyere usoro ịwa ahụ ma ọ bụ nwee ọrịa shuga, ọ dị mkpa ịtụle ekwe omume iji nkwadebe insulin.
Ọ dị mkpa ịdọ ndị ọrịa aka na ntị banyere ịba ụba nke hypoglycemia n'ihe banyere ị etụ ọgwụ ethanol, ọgwụ mgbochi mkpali na-abụghị steroidal, agụụ. N'ihe banyere ethanol, ọ ga-ekwe omume ịzụlite ọrịa disulfiram dịka (mgbu afọ, ọgbụgbọ, ọgbụgbọ, isi ọwụwa).
Ọ dị mkpa iji dozigharị ọgwụ ahụ na oke anụ ahụ ma ọ bụ nke mmetụta uche, mgbanwe nri
Kachasị emetụta ihe nke hypoglycemic ọgwụ bụ ndị agadi, ndị ọrịa na-anaghị enweta ezigbo nri, ndị ọrịa na-esighi ike, ndị ọrịa na-ata ahụhụ site na enweghi nri.
Na nmalite ọgwụgwọ, n'oge nhọrọ nha, ndị ọrịa na-ebute mmepe nke hypoglycemia anaghị atụ aro ka ha na-eme ihe chọrọ nlebara anya na ọsọ nke mmeghachi omume psychomotor.

Mpempe mwepụta
Mbadamba 80 mg
Na mbadamba 10 na mbadamba ihe na-acha uhie uhie nke ihe nkiri polyvinyl chloride na aluminom foil varnished.
3 ma ọ bụ 6 blisters nke nwere ntuziaka maka ojiji ka etinye n’otu kaadiboodu.

Ọnọdụ nchekwa
Ndepụta B. N'ebe kpọrọ nkụ, ebe ọchịchịrị na-adịghị elu karịa 25 Celsius.
Mee ka ụmụaka ghara iru.

Exbọchị mmebi
Afọ 2
Ejila oge emechaala.

Usoro ahịa ọgwụ ahịa
Site na ndenye ọgwụ.

A ga-agwa ndị mepụtara ya maka okwu a:
FARMAKOR Production LLC, Russia
Adreesị Mmepụta:
198216, St. Petersburg, Leninsky Prospect, d.140, lit. F
Adreesị iwu:
194021, St. Petersburg, nke abụọ Murinsky Prospect, 41, lit. A