Etu esi ewere Atomax na cholesterol?

Atomax na-ezo aka na ọgwụ ọgwụ-emume nke ọgbọ nke atọ, nke nwere mmetụta dị ala. Ọ bụ ngọngọ nke nhọrọ HMG-CoA reductase, enzyme nke na - egbochi njedebe cholesterol njikọ.

Ojiji nke iji ọgwụ ahụ dabara adaba na ọgwụgwọ hypercholisterinemia na thyroglobulin dị elu (TG). Site na Atomax, enwere ike ibunye metabolism nke mmanu mmanu ana - apusi iguzo nsonaazụ nke cholesterol di elu.

N'ime ihe a ị nwere ike ịchọta ozi zuru ezu banyere ọgwụ Atomax, ntuziaka maka ojiji, ọnụahịa, nyocha ndị ọrịa na ọgwụ ndị yiri ya.

Mwepụta wepụtara ya na ihe mejupụtara

Atomax bụ ọgwụ achọrọ iji gbochie HMG-CoA reductase, na-ebute mbelata nke cholesterol na sel imeju. N'adịghị ka statins nke ọgbọ mbụ, Atomax bụ ọgwụ nke sitere na sịntetik.

Na ahịa ọgwụ ị nwere ike ịchọta ọgwụ ọgwụ ụlọ ọrụ India HeteroDrags Limited na osisi ụlọ nke Nizhfarm OJSC, Skopinsky Pharmaceutical Plant LLC.

Atomax dị n'ụdị mbadamba ọcha nke gbara agba gburugburu akụkụ ya. Site n’elu kpuchie ha akpụkpọ ihe nkiri. Otu ngwugwu nwere mbadamba iri atọ.

Mbadamba ụrọ ahụ gụnyere 10 ma ọ bụ 20 mg nke ihe na - arụ ọrụ - atorvastatin calcium trihydrate.

Na mgbakwunye na akụrụngwa bụ isi, mbadamba ihe ọ bụla na shei ya nwere ụfọdụ ego:

sodium croscarmellose,
mee ka talcum ntụ ntụ dị ọcha
lactose n'efu
stereta magnesium,
ọka ọka
carbon dioxide
povidone
silikon dioxide anakpo ahihia,
crospovidone
triacetin

Na mgbakwunye, a na-etinye ụfọdụ etu titanium dioxide na nkwadebe.

Usoro nke ihe eji arụ ọrụ

Dịka anyị kwuru na mbụ, a na-enweta mmetụta mmachi nke Atomax site na igbochi HMG-CoA reductase. Ebumnuche bụ isi nke enzyme a bụ ịtụgharị methylglutaryl coenzyme A ka mevalonic acid, nke bụ usoro nke cholesterol.

Atorvastatin na-arụ ọrụ na mkpụrụ ndụ imeju, na-ebelata ego nke LDL na mmepụta cholesterol. Ejiri ya maka ndị ọrịa na-arịa ọrịa hypercholesterolemia, nke enweghị ike ịgwọ ya na ọgwụ ndị ọzọ belata cholesterol. Mgbanwe nke mbelata cholesterol na-adabere na oke nke ihe bụ isi.

Atomax adighi akwado ka ewere ya n’oge nri, dika iri nri na - ebelata oke nke mmiri. Ngwakọta ahụ na-arụ ọrụ na-etinye obi gị dum na ngọngọ nri. A na-ahụ ọdịnaya kachasị nke atorvastatin ruo awa 2 mgbe etinyere ọrụ.

N'okpuru nduzi nke enzymes pụrụ iche CY na CYP3A4, metabolism na-eme na imeju, n'ihi nke a na-emepụta metabolites parahydroxylated. Mgbe ahụ, ewepụrụ metabolites ahụ n’onwe ya yana bile.

Ihe ngosi na contraindications maka iji ogwu

Ejiri Atomax belata cholesterol. Dọkịta na-edepụta ọgwụ ọgwụ na nri nri maka ọrịa ndị dị ka isi, heterozygous ezinụlọ na hypercholesterolemia na-abụghị nke ezinụlọ.

Iji mbadamba ụrọ dịkwa mkpa maka ụba mkpụrụ nke thyroglobulin (TG), mgbe ọgwụgwọ nri anaghị ebute nsonaazụ ha chọrọ.

Atorvastatin na -ebelata cholesterol nke ọma na ndị ọrịa nwere hypercholesterolemia homozygous familialia, mgbe ọgwụgwọ na nri anaghị agwọ onwe ya.

A machibidoro Atomax ụfọdụ ụdị ndị ọrịa. Ntụziaka ahụ nwere ndepụta nke contraindications maka iji ọgwụ ahụ:

Childrenmụaka na ndị nọ n’agbata afọ 18.
Oge ị ga-amụ nwa na inye ya ara.
Hepatic dysfunction nke amaghi.
Ọgwụ mkpuchi nke ihe ndị dị na ngwaahịa ahụ.

Ejiri ọgwụ ahụ jiri nlezianya mee ihe banyere hypotension akwara, nleghara anya nke electrolytes, malfunctions nke usoro endocrine, ọrịa imeju, a chronicụrụma na-adịghị ala ala na Akwụkwụ na - enweghị ike ịchịkwa.

Ntuziaka maka iji ọgwụ ahụ

Isi ihe dị mkpa na ọgwụgwọ Atomax bụ idebe nri pụrụ iche. Ihe oriri na-edozi ahụ iji belata oriri nke nwere cholesterol dị elu. Ya mere, nri anaghị ewepụ iri viscera (akụrụ, ụbụrụ), yolks akwa, bọta, anụ ezi, wdg.

Usoro onorvastatin dịgasị iche site na 10 ruo 80 mg. Dịka iwu, dibịa bekee depụtara ọgwụ izizi nke 10 mg kwa ụbọchị. Ọtụtụ ihe na-emetụta usoro ị aụ ọgwụ, dị ka ọkwa nke LDL na cholesterol zuru oke, ebumnuche ọgwụgwọ na arụmọrụ ya.

Ibawanye usoro ogwu nwere ike rụrụ mgbe ụbọchị 14-21 gachara. N'okwu a, ntinye nke lipids na plasma ọbara bụ ihe amanyere.

Mgbe ọgwụgwọ 14 gachara, a na-achọpụta mbelata nke cholesterol, mgbe ụbọchị iri abụọ na abụọ gachara, a na-enweta ike ọgwụgwọ kachasị. Site na usoro ọgwụgwọ ogologo oge, metabolism metabolism na-alaghachi na nkịtị.

Must ga-echekwa ọgwụ a ebe a na-echekwa ya site na obere ụmụaka. Usoro nchekwa nke nchekwa dị iche na 5 Celsius Celsius.

Ndụ shelf bụ afọ abụọ, mgbe oge a gasịrị, amachibido ị medicineụ ọgwụ ahụ.

Ihe Pot Pụrụ Ime na do Overụbiga mmanya ókè

A machibidoro ịnwe nchịkwa nke ọgwụ maka ọgwụgwọ ọgwụ ọgwụ.

Mgbe ufodu, ogwu nwere ike ibute mmeghachi omume ojoo n’onye oria.

Tupu iji Atomax, ịkwesịrị ịgakwuru dọkịta gị.

Akwụkwọ ntụziaka a na - ekwupụta omume enwere ike ịme ụdị mmetụta ndị a:

Ọgba aghara nke usoro akwara dị n’etiti: ọrịa asthenic, ụra na-adịghị mma ma ọ bụ ụra, ụra abalị, amnesia, dizziness, isi ọwụwa, ịda mba, tinnitus, nsogbu obibi, paresthesia, neuropathy akụkụ, uto ọgba aghara, ọnụ akọrọ.
Mmeghachi omume metụtara akụkụ anụ ahụ na -akụ ahụ: mmepe nke ntị chiri, nkụkpọ nkụ.
Nsogbu nke akwara na akwara obara: aholebonia, anemia, angina pectoris, vasodilation, orthostatic hypotension, thrombocytopenia, ubara obi obi, arrhythmia.
Dysfunction of the digestive tract and biliary system: afọ ntachi, afọ ọsịsa, ọgbụgbọ na ọgbụgbọ, mgbu nke afọ, hepatic colic, belching, obi mgbawa, ịba ụba gas na -eme, nnukwu pancreatitis.
Mmeghachi omume nke anụ ahụ: itching, ihe ọkụ ọkụ, eczema, mgbu nke ihu, eserese.
Nsogbu nke uru ahụ: akwara olu nke ala akụkụ ahụ, azụ mgbu nke nkwonkwo na azụ, myositis, rhabdomyolysis, ogbu na nkwonkwo, iwe nke gout.
Urination na-enweghị nsogbu: urination na-egbu oge, cystitis.
Ọkpụkpụ nke plọgum lab: hematuria (ọbara na mmamịrị), albuminuria (protein na mmamịrị).
Mmeghachi omume ndị ọzọ: ọbara mgbali elu, agụụ mmekọahụ na-ebelata, dysfunction dysfunction, alopecia, sweating riri nne, seborrhea, stomatitis, goms ọbara ọgbụgba, eriri akụkụ, ikpu na imi.

Atụ atorvastatin dị elu na-eme ka ohere nke akụrụ ghara ibilite, yana ọrịa myopathy (ọrịa neuromuscular) na rhabdomyolysis (ogo nke myopathy).

Ruo ugbu a, enweghi ọgwụ pụrụ iche maka ọgwụ a.

Ọ bụrụ n ’ihe ịrịba ama nke ịdoụbiga mmanya ókè, a ga-ewepụ ha. N'okwu a, ọrịa ịba ọcha n'anya anaghị arụ ọrụ.

Mmekọrịta na ọgwụ ndị ọzọ

Ihe ike ọgwụ na-arụ ọrụ nwere ike ịmeghachi n'etiti onwe ha n'ụzọ dị iche iche, n'ihi nke ọgwụgwọ nke Atomax nwere ike iwusi ike ma ọ bụ mee ka ọ daa mba.

Ohere iji mekọrịta n'etiti ihe dị iche iche nke ọgwụ dị iche iche chọrọ ka onye ọrịa ahụ kọwaara dibịa na-aga ahụ maka ị medicationsụ ọgwụ na-emetụta ọrụ Atomax.

Ntuziaka maka ojiji nke ọgwụ hypoliplera, enwere ozi zuru oke banyere njikọta ya na ọgwụ ndị ọzọ.

Ejikọtara ọnụ na cyclosporine, erythromycin, fibrates na ndị na-egbochi antifungal (otu ìgwè nke ihe mgbu) na-amụba ohere nke neuromuscular pathology - myopathy.
N'oge nyocha, otu oge nlekọta Antipyrine anaghị eme mgbanwe dị ukwuu na ọgwụ ọgwụ. Ya mere, a na-anabata nkwonkwo ọgwụ abụọ.
Yiri ojiji nke ihe na-egbochi ihe nwere magnesium hydroxide ma ọ bụ aluminom hydroxide na-eduga n'ịbelata ọdịnaya nke atorvastatin na plasma.
Njikọ nke Atomax yana ọgwụ mgbochi afọ ime nke nwere tinylestradiol na norethindrone na-abawanye AUC nke ihe ndị a.
Ojiji nke colestipol n’otu oge belata ogo atorvastatin. N'aka nke a na-eme ka mmerụ ahụ dị ala belata.
Atomax nwere ike ịmụba digoxin na n'ọbara. Ọ bụrụ na ọ dị mkpa, ịgwọ ọgwụ a kwesịrị ka ọ bụrụ nlekọta ahụike siri ike.
Njikwa nje ọzọ nke Azithromycin anaghị emetụta ihe ndị dị na Atomax nọ n'ọrụ na plasma ọbara.
Ojiji nke erythromycin na clarithromycin na-eme ka mmụba nke ọkwa nke atorvastatin dị n’ọbara.
N'oge nyocha nke ụlọ ọgwụ, achọpụtaghị mmeghachi omume kemịkal n'etiti Atomax na Cimetidine, Warfarin.
A na-achọpụta mmụba na ọkwa nke ihe na-arụ ọrụ na nchikota nke ọgwụ yana ndị na-egbochi nchebe.
Ọ bụrụ na ọ dị mkpa, dọkịta na-enye gị ohere ikpokọta Atomax na ọgwụ, nke gụnyere Amplodipine.
Emebeghị nnyocha banyere otú ọgwụ si emekọrịta ọgwụ ọgwụ mgbochi.

Site na njikọta nke Atomax na estrogens, enweghị ihe ọjọọ ọ bụla hụrụ.

Ọnụahịa, nyocha na analogues

O nweghi ihe omuma banyere odi nma nke iji Atomax na intaneti. Eziokwu ahụ bụ na ka ọ dị ugbu a, a na-eji ihe oyiyi ọgbọ IV eme ihe na ahụike. Ọgwụ ndị a nwere usoro onunu ogwu ha, ha anaghị akpata ọtụtụ nsonaazụ.

Atomax siri ike ịzụta na ụlọ ahịa ọgwụ nke obodo n'ihi eziokwu ahụ bụ na ọ dịchabeghị eji ya. Na nkezi, ọnụahịa nke ngwugwu (mbadamba 30 nke 10 mg) sitere na 385 ruo 420 rubles. Ọ bụrụ na ọ dị mkpa, enwere ike inye ọgwụ ahụ ntanetị na weebụsaịtị nrụọrụ weebụ nke ndị nrụpụta.

Onu ogugu n’ilele banyere ihe nlere na egbusi ike n’ogugu ha. Maka oge kachasị, ha na-ekwu maka omume nke mmeghachi omume ọjọọ mgbe ha na-a theụ ọgwụ ahụ. Agbanyeghị, enwere echiche dị iche.

N'ihi contraindications dị iche iche na mmeghachi omume na-adịghị mma, mgbe ụfọdụ, dọkịta na-edepụta otu okwu (ọgwụ nwere otu ihe ahụ na-arụ ọrụ) ma ọ bụ analog (nke mejupụtara ihe dị iche iche, mana na-ewepụta ụdị ọgwụgwọ ahụ).

Enwere ike ịzụta okwu Atomax ndị a na ahịa ọgwụ Russia.

Atovastatin (Mba. 30 na 10 mg - 125 rubles),
Atorvastatin-Teva (Mba. 30 maka 10 mg - 105 rubles),
Atoris (Nọmba 30 maka 10 mg - 330 rubles),
Liprimar (Nke 10 na 10 mg - 198 rubles),
Novostat (Mba. 30 maka 10 mg - 310 rubles),
Tulip (Nke 30 maka 10 mg - 235 rubles),
Torvacard (Nke 30 maka 10 mg - 270 rubles).

N'etiti analogues nke Atomax dị irè, ọ dị mkpa ịmata ọdịiche dị iche iche ọgwụ ọjọọ:

Akorta (Mba 30 maka 10 mg - 510 rubles),
Krestor (Nke 7 maka 10 mg - 670 rubles),
Mertenil (Nke 30 maka 10 mg - 540 rubles),
Rosuvastatin (Mba. 28 na 10 mg - 405 rubles),
Simvastatin (Mba. 30 na 10 mg - 155 rubles).

N'ịga ọmụmụ ọgwụ Atomax nke ọma, ntuziaka maka ojiji, ọnụahịa, analogues na echiche nke ndị na - ere ahịa, onye ọrịa ahụ, ya na ndị ọkachamara na - aga ya, ga - enwe ike iji echiche ichebara mkpa ị forụ ọgwụ ahụ.

Enyere ozi banyere akpụ na vidiyo na edemede a.

Ngwakọta, ụdị ntọhapụ

Ihe Atomax nọ n'ọrụ atorvastatin. A na-arụ ọrụ inyeaka site na carbon dalson, shuga mmiri ara ehi, cellulose, croscarmellose sodium, povidone K-30, magnesium stearate, hypromellose, talc, titanium dioxide, triacetin.

Atomax - mbadamba ọcha na-acha ọcha nwere ọchichị iji kwalite nkewa. A na - emepụta ụdị ọgwụ abụọ ahụ na - arụ ọrụ nwere ọdịnaya nke 10 ma ọ bụ 20 mg.

Omume ọgwụ

Ofkpụrụ nke atorvastatin dabere na ikike ya igbochi ọrụ nke HMG-CoA reductase. Enzyme a bụ maka ibido otu n'ime usoro izizi nke cholesterol. N'otu oge ahụ, Atomax na-egbochi njikọ nke sterol, na-eme ka mbelata ọkwa ya. Iji kwụọ ụgwọ ụkọ cholesterol, a na-eme ka mbibi nke lipoproteins dị ala “emerụ emerụ” (LDL), nke nwere ihe dị mkpa na-arụ ọrụ. N'otu oge ahụ ahụ na-eme ka njikọ lipoproteins dị elu nke “dị mma” (HDL) dị elu, nke na-ahụ maka inyefe sterol site na akwara anụ ahụ.

Mgbanwe na mkpokọta cholesterol, lipoproteins nwere ike igbochi mmepe nke atherosclerosis, yana ọrịa ndị metụtara ya - ọnya afọ, nkụchi obi, necrosis nke nsọtụ ya.

Ntinye uche nke atorvastatin kachasị na ọbara na - apụta n'ime awa 1-2 ka nchịkwa gasịrị. Ike igbochi ya ji mkpụrụ 20-30. Ọgwụ ahụ na-ewepụta ọgwụ site na imeju, obere mmamịrị na mmamịrị. Nke a na-enye ohere ka edee Atomax maka nsogbu gbasara akụrụ, mana chọrọ iji nlezianya mee ndị ọrịa nwere ọrịa imeju.

Mlọ ọgwụ

Ọgwụ nwere mmetụta akpọrọ hypoliplera. Usoro nke usoro a dabere na ikike asọmpi ya na-egbochi HMG-CoA reductase - isi enzyme dị na ntụgharị methylglutaryl coenzyme A n'ime mevalonic acidmetụtara ihe ndị na - eme steroid, gụnyere cholesterol. TG na cholesterol N'ime imeju na-etinye ya na VLDL, ha banyezie n'ọbara ọbara ma bufee ya na anụ ahụ. Ọzọkwa, VLDL mepụtara site na VLDL, nke, mgbe ya na ndị na-anabata LDL na-emekọrịta ihe, na-ejigide ya.

Etu ahu di iche atorvastatin bụ imeju na usoro njikọ ya cholesterol na mkpochapu nke LDL. Atomax belata njikọta cholesterol ma belata ọnụ ọgụgụ nke LDL. Ọgwụ ahụ dị irè maka ndị ọrịa nwere homozygous hypercholesterolemiaọgwụ ndị ọzọ anaghị agwọ ọrịa. A na-ahọrọ ọ̀gwụ nke ọgwụ n’otu n’otu n’iburu n'uche ọgwụgwọ ọgwụgwọ, ebe ọ bụ na mbelata nke mbelata cholesterol kwekọrọ na ọgwụ ọgwụ ahụ.

Mlọ ọgwụ

Atomax etinyela onwe ya na ọnya nri, nri oriri na-ebelata oke nke oriri. Cmax - ihe dị ka awa abụọ, bioavailability dị larịị nke 30%, nke a bụ n'ihi usoro metabolism nke ọgwụ n'oge "ụzọ mbụ" na mucosa na eriri afọ.

Metabolized site enzymes CYP3A4 5 na CY n’imeju ka imeju metabolites akpachapụrụ anyaya na ogwugwo ogwu di elu. Emere ya nke ọma na sistemụ ịba ọcha n'anya. T1 / 2 ihe dị ka awa iri na ise.

Ihe ngosi maka ojiji

Iji belata mkpokọta cholesterol (na nri) na ndị ọrịa nwere isi hypercholesterolemiaabụghị ezinụlọ na ezinụlọ heterozygous hypercholesterolemia,
Tba ụba serum TG n’arụ ndị ọrịa ọrịa ọgwụ anaghị agwọ ọrịa,
Iji belata ọkwa niile cholesterol n'ime ndị ọrịa nwere hypercholesterolemia homozygous familialia, na arụmọrụ nke usoro ọgwụgwọ nri na ụzọ ọgwụgwọ anaghị agwọ ọrịa.

Ihe ngbanwe

Nnukwu mmetụta nke Atomax, ọrịa ọrịa imeju na-amaghị, afọ n'okpuru 18, tụụrụ imelactation. Jiri nlezianya kpachara anya banyere ndị ọrịa nwere echiche elezighị anya, hypotension akwara, ọrịa endocrine, ọrịa imeju, na-arịa ọrịa ala ala alisụrụmaenweghị ike ịchịkwa Akwụkwụ na-adọ.

Nsonaazụ

Ọrịa Asthenicọnụ kpọrọ nkụ iro ụrama obu ehighi ura, anya ntughari, amnesia, isi ọwụwan’abali paresthesiansogbu neuropathy, nsogbu uche, ịda mba, mgbakasị ụlọ, tinnitus, ajọ omume, ntị chiri, mkpọtụ nkụ, palpitations, obi mgbu, orthostatic hypotension, anaemia, phlebitis, vasodilation, thrombocytopeniaimi afọ ọsịsa/afọ ntachi, ọla kọpa, arrhythmiagoms na-agba ọbara colic ịba ọcha n'anya, flatulencebelching, ọgbụgbọ, obi mgbawa, ọria aruafọ mgbu vomiting stomatitisọbara ọgbụgba nke akụkụ anọ myositisnkwonkwo ụkwụ, mgbu azụ, nkwonkwo ụkwụ, rhabdomyolysis, ọrịa ogbu na nkwonkwo, albuminuriambelata libido ahu otutu, ọsụsọ, seborrhea, hematuriaọbara ọgbụgba enweghi ikeAkpụkpọ ahụ, ntutu isi ya, epididymitisihe ojoo gout, amu amu, alopecia, ọzịza nke ihunjigide urinary ndiseịba ụba ahụ.

Ntụziaka Atomax maka ojiji (Usoro na usoro onunu ogwu)

Ekwesịrị ịgwọ Atomax megide ihe ndabere nri ivuna-aga n'ihu n'oge ọgwụgwọ. Usoro onunu ogwu sitere na 10-80 mg. Na nkezi, ọgwụ mbụ bụ 10 mg ma were ya 1 otu oge kwa ụbọchị, n'agbanyeghị nri oriri. A họrọ usoro ị theụ ọgwụ ahụ maka onye ọrịa site na ọkwa cholesterol/ LDL, ihe mgbaru ọsọ ọgwụgwọ na nrụpụta ọgwụgwọ. Na mbido ọgwụgwọ yana mmụba na usoro onomax, ọ dị mkpa ijikwa ọdịnaya nke lipids na plasma ọbara kwa izu 2-3 ma dozie dose ahụ.

Ọgwụgwọ ahụ gosipụtara onwe ya n’abidoghị izu abụọ, ma karịa - ka izu anọ gachara, nke eji ọgwụ ogologo oge chekwaa nke ọma.

Atomax: ngosiputa maka iji

Dabere na ntuziaka ndị a, Atomax ka enyere ndị ọrịa nwere:

isi hypercholesterolemia, heterozygous ezinụlọ, hypercholesterolemia na-abụghị nke ezinụlọ.
gwakọtara na hyperlipidemia,
hypertriglyceridemia,
dbetalipoproteinemia.

Atomax dị irè igbochi nsogbu nke atherosclerosis na ndị ọrịa nwere ihe mgbaàmà nke ọrịa akwara ọbara. Edere ya ndị mmadụ n'ihe ize ndụ nke ibute ọrịa obi na-akpata obi dịka ihe abụọ ma ọ bụ karịa: ise siga, oke ibu, afọ, erighị ihe na-edozi ahụ, ụdị ndụ anaghị arụ ọrụ.

Ofzọ nke ngwa, usoro onunu ogwu

Atomax ka edeputara naanị dika mgbakwunye na nri, ma oburu na ọ ghọrọ adighi ike. Ekwesịrị ịhụ ya n'oge oge ọgwụgwọ niile.

Mgbe ị na-ewere statin, ị ga-agbaso iwu dị mfe. Na-a tabletụ mbadamba nkume Atomax n'otu oge, 1 oge / ụbọchị, nke nwere nnukwu mmiri. Enweghi ike ịta ya ahụhụ, gwepịa ya.

Ọgwụgwọ bidoro na obere usoro onunu ogwu. M na-elekwasị anya na mgbanwe na cholesterol, lipoproteins, dọkịta nwere ike ịgbanwe ọgwụ ahụ mgbe izu 2-4 gachara. Ogwu a kacha anabata bụ 80 mg. Ọ bụrụ na atorvastatin dị otú ahụ anaghị arụ ọrụ, a na-eji statin dị ike karịa ma ọ bụ ọgwụ cholesterol dochie dochie Atomax n'oge usoro ọgwụgwọ.

Maka ọtụtụ ndị ọrịa nwere hypercholesterolemia bụ isi, yana hyperlipidemia agwakọta, 10 mg nke ọgwụ zuru oke.

Ndị nwere hypercholesterolemia homozygous familialia na-a theụ ọgwụ ahụ na 80 mg ugboro 3 / ụbọchị (20 n'ụtụtụ, 20 n'ehihie, 40 na mgbede). Dịka iwu, nke a zuru iji belata cholesterol site na 18-45%.

Ekwesịrị ịkpachara anya mgbe ị na-edegara ndị oria Atomax akwụkwọ:

ị alcoholụbiga mmanya ókè
nwere ọrịa imeju
na-arịa ọrịa metabolic, nsogbu nke homonụ, warakwụ, hypotension, ọkpụkpụ akwara ọkpụkpụ,
ya na nnukwu ịwa ahụ.

Atomax: ntuziaka maka ojiji, ọnụahịa, nyocha, analogues

Atomax bụ ọgwụ nwere ike ịmịnye mmadụ mmerụ ahụ nke ndị otu HMG-CoA reductase inhibitors.

A na-eji ya belata mkpokọta apolipoprotein B, cholesterol ngụkọta, triglycerides, LDL na VLDL n'ime ndị ọrịa na-ata ahụhụ hypercholesterolemia, ezinụlọ na ndị na-abụghị heterozygous hypercholesterolemia na ụdị hyperlipidemia na ndị ọrịa nwere dysbetalipoproteinemia nke na-agbago ọbara atọ mmetụta nri. Ọ contraindicated bụrụ na nke nnukwu ọrụ nke enzymes imeju, hypersensitivity, lactation, ọrụ imeju pathologies, ime na na omume.

Nkọwa na ihe mejupụtara

Atomax bụ biconvex mbadamba okirikiri nwere mkpuchi nke ihe nkiri na-acha ọcha. Anabataghị ike ihe adịghị ike ngbacha elu.

Otu mbadamba 1 nwere 10 mg ma ọ bụ 20 mg nke atorvastatin.

titanium dioxide
crospovidone
stereta magnesium,
povidone
sodium croscarmellose
ntụ ntụ talcum
silloidal anwụrụ silica,
lactose
stachi
primellose 15 CPS.

Maka ndi okenye

Edere Atomax maka ndị okenye okenye nwere ọnọdụ dịka:

mbelata nke cholesterol zuru oke, triglycerides, apolipoprotein B, LDL na VLDL na ndị ọrịa nwere hypercholesterolemia bụ isi, ndị na-abụghị ezinụlọ na heterozygous hypercholesterolemia na hypercholesterolemia na-agwakọta,
usoro ọgwụgwọ nke ndị ọrịa na-ata ahụhụ site na nnukwu triglycerides na dysbetalipoproteinemia (na-enweghị mmetụta kwesịrị ekwesị na usoro ọgwụgwọ nri).

Atomax bụ contraindicated na ụmụ na-eto eto n'okpuru afọ 18.

Mmekọrịta na ọgwụ ndị ọzọ

Ihe ize ndụ nke myopathy n'oge ọgwụgwọ na ọgwụ ndị ọzọ nke klas a na-abawanye site n'iji cyclosporine, erythromycin, fibrates, antifungals.

Site na ojiji atorvastatin na erythromycin ma ọ bụ clarithromycin, a na-achọpụta ihe na-abawanye ọdịnaya nke atorvastatin na ọbara ọbara.

Ihe atorvastatin jikọtara ya na ndị na - egbochi ya, yana mmụba nke ọkwa onorvastatin.

Ntụziaka pụrụ iche

Tupu ịmalite Atomax, onye ọrịa ahụ ga-enyerịrị usoro hypocholesterol kwesịrị, nke ọ kwesịrị ịgbaso n'oge ọgwụgwọ.

Ojiji nke HMG-CoA reductase inhibitors iji belata egbugbere ọnụ ọbara nwere ike ịkpalite mgbanwe na usoro biochemical nke na-egosipụta ọrụ imeju.

Achọpụtaghị mmetụta ọjọọ na ịkwọ ụgbọ ala, agbanyeghị na enwere ọdịdị nke mmetụta ndị ọzọ, a ga-akpachara anya mgbe ị na-eme ihe egwu nwere ike ime.

Ọnọdụ nchekwa

Atomax kwesịrị ịchekwa ya ka ụmụaka ghara iru, n’ebe kpọrọ nkụ, ka echedo site na ìhè anyanwụ. Ọnọdụ nchekwa - ihe karịrị 25 Celsius С.

Ndụ shelf bụ afọ 2.

Ojiji ọgwụ Atomax anaghị enyekarị ọgwụgwọ ọgwụgwọ maka ndị ọrịa niile. N'akụkụ a, na ahịa ọgwụ enwere ọtụtụ ọgwụ yiri nke ahụ.

Mertenyl

Mertenil bụ ihe na - eme nhọrọ na asọmpi nke HMG-CoA reductase. Ọgwụ na-arụpụta akpọ akpọ akpọlata.

Edere Mertenil maka hypertriglyceridemia, hypercholesterolemia, ọnọdụ ọnyụnyụ jikọtara, yana maka isi mgbochi nke ọrịa obi. Ọgwụ nwere ọtụtụ contraindications na mgbochi maka ojiji.

Tupu ịmalite ọgwụgwọ, a na-atụ aro ịkpọtụrụ ụlọ ọrụ ahụike ma gakwuru dọkịta.

Atotex

Atotex bụ ọgwụ nwere ike ịmịnye mmadụ azụ nke nwere atorvastatin dịka ihe eji arụ ọrụ. A na-eji ya maka otu ihe iji gosipụta ọgwụ Atomax. Amachibidoro Atotex maka iji n’oge afọ ime, na-a breastụ ara, na-eleghara igbochi afọ ojuju site n’aka ndị ọrịa nke afọ ịmụ nwa, ọrịa imeju na-arịa, nnagide ya na n’agbata afọ 18.

Ihe eji agwu Tulip

Tulip ọgwụ bụ nke usoro ọgwụ nke nhọrọ (nhọrọ) na-egbochi asọmpi HMG-CoA reductase.

A na-eji ya agwọ ọrịa hypercholesterolemia, ụdị ejikọtara hyperlipidemia, yana dịka ihe ọzọ na nri iji kpochapụ homozygous na heterozygous familial hypercholesterolemia.

A machibidoro iwu maka hypersensitivity, ọrịa na-arụ ọrụ imeju, ọdịda imeju, ịtụrụ ime, na-a breastụ ara, na-amụba ọrụ nke enzymes imeju nke amaghi site, na-eleghara ojiji nke igbochi afọ ojuju zuru ezu site na ndị ọrịa afọ ọmụmụ na omume ụmụaka.

Livazo

Akụkụ nọ n'ọrụ bụ calcium pitavastatin. Ọgwụ hypolipPs.

Ihe ngosiputa maka iji Livazo gunyere oria ndia: mbelata na LDL na VLDL, triglycerides, cholesterol na apolipoprotein B zuru oke banyere oria nke heterozygous dibo mbu hypercholesterolemia na udiri dyslipidemia. Njere ọgwụ mgbochi bụ otu ọnọdụ ahụ maka ọgwụ ị nweburu.

Vasilip

Ọgwụ nke na-eme ka egbugbere ọnụ dị n'ụdị mbadamba ihe ndị nwere simvastatin dịka ihe na-arụ ọrụ.

Edere ya dị ka mgbakwunye nri nri pụrụ iche maka isi ma ọ bụ ezinụlọ (homozygous) hypercholesterolemia, hypertriglyceridemia, dyslipidemia agwakọta, yana kwa dịka prophylactic maka ọrịa obi na ọrịa na-arịa okike. Amachibidoro ọgwụ Vasilip ọgwụ maka ọrịa akwara (gụnyere nnukwu mkpụkọ nke transaminases), ọmụmụ nwa, ịtụrụ ime, anabataghị ya na ụmụaka na-erubeghị afọ 18.

Lovagexal

Mbadamba nkume ndị dị na lovagexal nwere akụkụ na-arụ ọrụ nke lovastatin. O doro anya na ọgwụ a ga - eji mee ihe ma ọ bụrụ na ọ dị mkpa iji belata ọkwa LDL, triglycerides, VLDL na cholesterol dị n'ọbara na hypertriglyceridemia na isi yana hypercholesterolemia jikọtara ọnụ.

A na - egbochi ọgwụ ọgwụ Lovagexal maka ụmụaka na - erubeghị afọ iri na abụọ, na ndị ọrịa na - ata ahụhụ site na akụrụ ma ọ bụ ọrịa hepatic, yana nnukwu ọnọdụ nke ahụ.

N'ime oge mmegharị ahụ na inye nwa ara, ọgwụ anaghị enye ya ọgwụ.

Ọnụ ahịa Atomax dị na nkezi site na 81 ruo 390 rubles.

Irè ọgwụ Atomax na-emegide cholesterol

Ndị ọrịa na-ajụ otu esi ewere Atomax maka cholesterol? Iji nwee echiche gbasara ọgwụ, ịkwesịrị ịma nzube ya, ụdị, mmetụta ya.

Ọ bụrụ na mmadụ nwere mmụba ma ọ bụ ibelata ihe ọ bụla dị na ahụ, nke a nwere ike ibute imebi arụ ọrụ ụfọdụ. Iji weghachite nguzozi, a na-eji ọgwụ ọjọọ eme ihe, otu n'ime ha bụ ọgwụgwọ a.

Na cholesterol, Atomax na-enye ọgwụgwọ kachasị dị irè.

Etu esi ewere choromerol na Atomax?

Ọgwụ dị n'ụdị mbadamba nkume. Akụkụ ha bụ convex, elu ya siri ike. N’otu akụkụ enwere ihe ọghọm. Ha nwere shei soluble, bu nke nwere agba di ọcha. Mbadamba mbadamba ahu juru na blisters, nke edochiri n’ime igbe kaadi riri oke.

ihe na-arụ ọrụ (ihe mejupụtara), nke bụ atorvastatin,
ọka ọka
carbon dioxide
lactose
povidone
sodium croscarmellose
sịlịkọn
ikuku na-egbu egbu
crospovidone.

Gịnị bụ shei nke mbadamba ihe? Site na triacetin, talc ọcha, primmeloza, titanium dioxide.

Etu esi a Atụ mmanya Atomax, ntuziaka maka ojiji nke dị na nchịkọta, onye ọ bụla kwesịrị ịma. Nke a bụ ọgwụ na-eme ka ike gwụ ala, bụ nke ebumnuche iji wedata cholesterol, nke na - emetụta ahụ mmadụ.

N'akuku ndi otu statins. Ọzọkwa, ọgwụ bụ asọmpi nhọrọ na-egbochi HMG-CoA reductase. Ezubere ya maka ọrụ ọzọ: iwetulata plasma lipoproteins.

Atomax nwere mmetụta bara uru na lipoproteins dị ala n'elu mkpụrụ ndụ akwara.

N'ihi ọgwụgwọ ahụ, a na-achọpụta mmụba a kapịrị ọnụ na ọrụ ndị na-anabata ndị LDL. Okwesiri ighota ihe ojoo di ma oria nke ischemia.

Ọgwụ anaghị enwe mmetụta ọjọọ n’ahụ.

Kedu mgbe ichere maka nsonaazụ? Iji hụ mgbanwe dị mma, ịkwesịrị ị were ọgwụ ọbụlagodi izu abụọ. Ekwesịrị iji ọgwụ ahụ otu ọnwa site na mmalite ọgwụgwọ. Mgbe usoro ahụ gwụchara, mmetụta ahụ ga-ahụ ogologo oge.

Ihe ngosi maka ojiji. Edere Atomax n'ọnọdụ ndị dịka:

Cholesterol dị elu.
Mmụba LDL-C mụbara.
Mmụba na thyroglobulin na apolipropylene B.
Ọ bụrụ na ọkwa nke serum TG abawanye.
N'okwu ahụ mgbe dysbetalipoproteinemia malitere.

Atomax anaghị adị irè ma ọ bụrụ na onye ọrịa anaghị eso usoro nri pụrụ iche nke dọkịta nyere. Ọgwụ a bụ ihe inyeaka ma na-eme yana njikọta na nri nri pụrụ iche.

Etu esi ewere ma kedụ ọgwụ ole eji ọgwụ a? Tupu ịmalite usoro ọgwụgwọ, onye ọrịa ahụ kwesịrị ịgbanwe gaa nri pụrụ iche na-ebelata ume nri. Ndị dọkịta na-atụ aro ịgwọ ọrịa iche iche maka onye ọrịa ọ bụla. Enwere ike ị medicineụ ọgwụ ahụ tupu oge nri, ka emesịa, na tupu nri n'oge oge ọ bụla n'ụbọchị. Ofgwọ ọgwụ dị irè site na nke a anaghị ebelata.

Kedu ka Atomax si emeso ọgwụ ndị ọzọ? N'okwu ahụ mgbe ejiri ọgwụ ahụ jikọta ya na erythromycin ma ọ bụ ndị na-ahụ maka antifungal, mmetụta ndị dị n'ụdị myopia nwere ike ime. Ekwesighi iji Atomax mee ihe yana njikọta nke nwere hydroxide na aluminom, ma ọ bụghị ya, itinye uche nke atorvastatin n'ọbara na-ebelata yana nsonaazụ ọgwụgwọ, n'otu n'otu.

Enwere ike iji Terfenadine mee ihe, ebe ọgwụ a na-ajụ taa adịghị agbanwe Njirimara nke ndị bụbu. Enwere ike iji ya mee ihe na estrogens - ọ dịghị ihe dị njọ ga-eme.

Emegideghị Warfarin na Cimetidine.

Ejila ya na ndị na - egbochi ya, n'ihi na nchikota a na - eme ka ịba ụba nke Atomax dị n'ọrụ. Ọ dị mkpa ịhapụ ndị na - egbochi ya, ma ọ bụ belata usoro onunu ogwu. Ekwesịrị ime nke a n'okpuru nlekọta ndị dọkịta.

Atomax bu onye iro cholesterol!

Mgbe ụfọdụ, ndị mmadụ nwere ike ịchọpụta mbelata ma ọ bụ nwekwuo arụmọrụ nke ụfọdụ ihe dị n'ime ahụ ma soro na-arụ ọrụ dị iche iche na akụkụ ahụ.

Agbanyeghị, na mmụba na ịta nke ihe dịka cholesterol, ọ na - edugakarị n'ọrịa nke ọrịa dị iche iche.

Iji weghachi ya, ma gbochie ihe kpatara nsogbu dị iche iche, A na-ejikarị Atomax eme ihe.

Ogwu a na-enye ezigbo ọgwụgwọ.

Iji zere ọdịdị nke nsonaazụ ndị ọzọ, ọ dị mkpa ịgbasochi anya ndụmọdụ nke dibịa na-aga.

1. Ntụziaka maka ojiji

Atomax bụ ọgwụ nwere ike ịmịnye mmadụ mmịfe nke so na otu nke statins. Ọ bụ ihe nhọta na-egbochi asọmpi HMG-CoA reductase tinyere aka na ntụgharị nke 3-hydroxy-3-methylglutaryl coenzyme A na mevalonic acid molecules. Ebumnuche ya belata cholesterol, yana plasma lipoproteins.

Nke a bụ n'ihi eziokwu ahụ bụ na mgbochi nke HMG-CoA reductase na-eme, na nchịkọta nke cholesterol n'ime sel akwara ji nwayọ nwayọ.

Na mgbakwunye, ọgwụ ahụ nwere mmetụta bara uru n'ịbawanye ọnụ ọgụgụ ndị na-anabata LDL n'elu mkpụrụ ndụ imeju, si otú a na-eme ka nkwalite na catabolism na-esochi nchịkọta LDL.

N’ihi nke a, enwere mmụba mara akara na ọrụ nke ndị na-anabata LDL. Ọzọkwa, na myirịta, ihe egwu enwere ike ibute ọrịa ischemic dị obere belata.

O kwesiri iburu n'uche na ogwu ahu enweghi mmasi ma obu aru aru n’ariri aru.

A ga - ahụta nsonaazụ ọgwụgwọ na - aga n'ihu ka ọ dị izu abụọ ka amalitechara ị ofụ ọgwụ. A na-ahụta nsonaazụ kachasị mgbe ọnwa gasịrị, wee dịgide ruo ogologo oge zuru ezu.

Ihe ngosi maka nnabata

A na-atụ aro mbadamba nkume Atomax iji duzie ọgwụgwọ dị mma nke ọrịa ndị a:

Asedbawanye ụba nke LDL-C.
Ihe cholesterol zuru oke.
Mmụba TG, yana apolipoprotein B.
Ihe ngosi HDL-C dị elu na-esote hypercholesterolemia bụ isi, hyperlipidemia jikọtara ọnụ, ezinụlọ na-abụghị heterozygous ma ọ bụ hypercholesterolemia.
Gba ụba serum TG.
Mmepe nke dysbetalipoproteinemia.

Ekwesịrị iji Atomax dịka ọgwụ ọzọ dabere na nri nri pụrụ iche.

Ofzọ nchịkwa na usoro onunu ogwu

Tupu ịmalite ọgwụgwọ ọgwụ a, onye ọrịa ahụ ga-agbaso usoro nri na-eme ka ọ dị ala.

Usoro akwadoro ịmalite bụ 10 mg otu ugboro kwa ụbọchị. Ọ bụrụ na ọ dị mkpa, enwere ike ịbawanye ya 80 mg otu ugboro n'ụbọchị. Theụ ọgwụ anaghị adabere n'oge ehihie, yana iri nri.

A na-enyekarị ndị ọrịa nwere hyperlipidemia ị gwakọtara ọnụ ma ọ bụ hypercholesterolemia dị elu karịa nke 10 mg otu ugboro n'ụbọchị.

3. Mmekọrịta Ọgwụ

Mmekọrịta nke mbadamba nkume Atomax na ọgwụ dị iche iche:

Therapygwakọta ọgwụgwọ na iji "Erythromycin", "Cyclosporin", ọgwụ dị iche iche, yana ọgwụ antifungal, nke ndị ọgwụ otu azole, na-abawanye n'ihe ize ndụ nke myopathy.
Ojiji ojiji nke ihe nkwụsị, nke gụnyere aluminom hydroxide ma ọ bụ magnesium hydroxide, bụ ihe kpatara mbelata nke itinye uche nke ọgwụ na-arụ ọrụ na plasma ọbara.
Njikọ nke Atomax na Antipyrine anaghị eduga mgbanwe mgbanwe dị ukwuu na ọgwụ ọgwụ nke ikpeazụ. Ya mere, enwere ike ijikọ ya na ọgwụ nke ihe mejupụtara.
N'ihi njikọta na “Colestipol,” a na-ahụta mbelata nke mkpokọ atorvastatin na plasma ọbara. N'okwu a, mmụba na mmetụ egbugbere ọnụ.
Ọ na - enwe ike ịba ụba nke ndọta nke "Digoxin" na plasma ọbara. Ya mere, site na ọgwụgwọ dị otú ahụ, a na-atụ aro ka onye ọrịa ahụ na-elekọta ndị ọkachamara na-agwọ ọrịa mgbe niile.
Erythromycin, yana Clarothromycin, na-ebute mmụba na ọkwa nke arụ ọrụ mbadamba nkume Atomax dị na plasma ọbara.
Njikọ ya na ọgwụ dịka Azithromycin anaghị emetụta ịdị irè nke atorvastatin na plasma ọbara.
Ọ ga-ekwe omume ịme ọgwụgwọ dị mgbagwoju anya site na iji ya mee ihe na usoro Terfenadine, n'ihi na Atomax agbanweghị akụrụngwa ya.
Ojiji Atomax nwere otutu mgbochi ogwu a na-ekwu okwu, nke bu estinyl estradiol nwere norethindrone, na - ebute mmụba dị ukwuu na AUC nke ihe ndị a.
Onweghi ihe ngosi nke mmetuta obula n’enweghi ihe ichoro mgbe ijikota mbadamba ndi a na ụdị estrogens nile.
Amabeghị etu Atomax si mekọrịta ọgwụ dị iche iche.
Enweghi mmekorita ogwu nke ogwu a na "Cimetidine", yana "Warfarin."
Ọ bụrụ na ọ dị mkpa, a na-ahapụ ọgwụ ahụ ka ọ jikọta ya na ndị nwere ọgwụ amplodipine.
Mgbe ejikọtara ya na ndị na-egbochi ya, a na-achọpụta na-abawanye ụba na ọnụọgụ atorvastatin na-abanye na plasma ọbara.