Insulin P: ọnụahịa na onye nrụpụta, iche

Taa, ekele ndị ọkà mmụta sayensị na ngwa agha nke endocrinologists enwere nkwadebe insulin nwere oge dị iche iche: dị mkpụmkpụ ma ọ bụ ogologo oge. N'aka nke ya, kewara nke ọ bụla n’ime ụmụ obere. Drugsdị ọgwụ a na - enyere ndị ọkachamara aka ịgagharị karịa mgbe ha na - ede ọgwụ, mepụta usoro nchịkwa glycemic onye ọ bụla, na - ejikọta ụdị insulin dị iche iche.

Ultra Short-eme insulin

Ọ dị iche na oge dị ntakịrị site na oge ịgba ọgwụ ruo na mmalite nke mbelata nke glycemia. Dabere na ụdị ihe eji eme ihe, enwere ike ịbelata shuga na-apụta 10-20 nkeji mgbe ịgba ntụtụ ahụ, nsonaazụ kachasị elu na-abụkarị mgbe awa 1-3 gasịrị, oge a ga-eme ya bụ awa 3-5 Ọ bụrụ na ọ dị gị mkpa ịmalite ngwa ngwa glycemia: Apidra, Humalog ma ọ bụ Novorapid (Flexpen na Penfill).

Short insulin

Ọgwụ nke otu a na-amalite ịrụ ọrụ oge 30-60 ka agba ahụ gasịrị, a na-ahụ ọkwa kachasị elu mgbe awa 2-4 gachara, nsonaazụ ahụ na-adịgide na ọkara awa 6-8. Ihe ndi siri ike di iche (ndi anumanu ma obu mmadu) nwere ihe ndia:

Aha ọgwụ: Actrapid MS, Actrapid NM, Biogulin R, Gensulin R, Monosuinsulin MK, Rinsulin R, Humulin Regular, Humodar R.

Insulin na-arụ ọrụ ogologo oge

Ndabere nke ogwu bu nchikota nke ihe ndi mmadu nwere otutu onodu hypoglycemic. Ekesinyere ya n’ime insulin nke dị ogologo ma dị ogologo. Ọgwụ nke ụdị nke mbụ na-amalite ime awa 1.5-2 mgbe ogwu ogbugba ahụ, mejupụta ọkwa ọbara dị elu n'etiti awa 3-12 mgbe ọ gbasịrị, ma na-achịkwa ọdịnaya glucose maka awa 8-12.

Ọgwụ dị ogologo oge: Br-Insulmidi MK, Biosulin N, Gensulin N, Protafan NM, Protafan MS, Humulin NP, Insuman Bazal, Humodar B.

Inye insulin

O nwere mmetụta nke iwetulata shuga mgbe 4-8 awa gachara ịgba ọgwụ, a na-enwe mmetụta na-abawanye elu na ọnụ mmiri mgbe awa 8-18 ma na-ejide njikwa glycemia maka nkezi nke awa 20-30.

Nkwadebe: Lantus, Levemir (Penfill na Flexpen).

Ọgwụ insulin na-ejikọ

Mmetụta hypoglycemic na-apụta ọkara otu awa mgbe nchịkwa n'okpuru anụ ahụ, na-agbasi ike mgbe awa 2-8 gasịrị ma na-achịkwa ọdịnaya glucose na-abụkarị site na awa 18 ruo 20.

Nkwadebe: Biosulin 30/70, Gansulin 30P, Gensulin M30, Insuman Comb 15 GT, Rosinsulin M mix 30/70, NovoMix 30 (Penfill na FlexPen).

Njirimara nke ogwu na ihe omume di iche

Ultrashort insulin

Nkwadebe nke ụdị a bụ analogues nke ihe mmadụ. Emebere ya na insulin mepụtara n’ahụ n’ime sel nke pancreas yana mkpụrụ ndụ homonụ na ọgwụ ndị na - eme obere oge bụ hexamers. Mgbe nchịkwa dị n'okpuru anụ ahụ, a na-etinye ha nwayọ nwayọ, yabụ itinye uche kachasị elu, nke ya na ihe ahụ etolite na anụ ahụ erichara nri.

Otu insulin mbụ dị mkpụmkpụ, nke amịpụrụ ugboro atọ karịa mmadụ, bụ lyspro. Nke a bụ usoro nke ihe oke ala, nke enwetara mgbe agbanwere amino acid abụọ n'ụdị ya. Ihe nwere ihe owuwu ohuru nwekwara udiri ihe ndi ozo: o na egbochi ogwu nke hexamers ma ya mere weputa ubara elu ogwu ahu n’ime obara ya na ime ka onu ya di elu.

Ihe atụ nke abụọ nke homonụ mmadụ bụ insulin aspart. A na - enwetakwa ya mgbe edochichara ihe eji arụ ọrụ, mana oge a, aspartic acid nke e boro ebubo na-adịghị mma ewebata insulin dị mfe kama ịkọwapụta. Apụ, dịka Lyspro, ọ na - eme ọsọ ọsọ ma na - agbaji n'ike n'ike.

Achọpụtara insulin glulisin ka ejiri aspargin (amino acid) jiri lysine dochie anya mmadụ, a gbanwere lysine ọzọ nọ n'ọnọdụ B29 ka ọ bụrụ acid glutamic. N'ihi nke a, enwetara ihe eji abanye ngwa ngwa.

Nkwadebe insulin mepụtara na-adabere n'ihe ndị a na-amalite ime ihe fọrọ nke nta ka ọ bụrụ ozugbo. A na-ahapụ ha ịbanye n'oge nri tupu ha eri nri ma ọ bụ ozugbo ha itụsịrị ya.

Short insulin

A na-akpọkarị nkwadebe nke otu a, n'ihi na ha bụ ndị ngwọta na-anọpụ iche acidity. Ezubere ya maka ntinye n'okpuru anụahụ, mana ọ bụrụ na ọ dị mkpa, a na-etinye ha na akwara, na n'ọnọdụ ndị jọgburu onwe ya, a na-anabata iwebata n'ime akwara.

Egosiputa ihe ngwa ngwa ha (on nkezi mgbe 15-25 nkeji) na oge adighi ezigbo ogologo ichebe mmetụta hypoglycemic (ihe dị ka awa 6). Ọtụtụ mgbe, a na-eji insulin eme ihe ngwa ngwa na ngalaba ndị ọrịa iji chọpụta otu onye ọgwụ ga-esi nye onye ọrịa ahụ. Mana a na-ejikwa ya n'ọnọdụ siri ike nke onye ọrịa, mgbe ọ dị mkpa iji mee ka ọrịa shuga kwụsị ngwa ngwa na stema ma ọ bụ nna nna. Na on / na mmetụta a na-enweta mgbe minit 5 gasịrị, yabụ, a na-enye ọgwụ ahụ ka ọ bụrụ mmiri iji belata ihe ize ndụ nke mgbanwe ngwa ngwa na ịta nke glycemia. Na mgbakwunye, a na-ejikwa insulin mkpụmkpụ dị ka anabolic, wee dezie ya na obere usoro.

Ọgwụ insulin etiti

Ọgwụ nke otu a na-eme nwayọ karịa: ha na-agbari nke ka njọ, na-ewere nwayọ nwayọ site na ebe injection, yabụ mmetụta hypoglycemic dị ogologo. A na - enweta usoro nke ime ihe site na iwebata ihe ndi puru iche na ikike igbochi oru nke insulin. Ọtụtụ mgbe, a na-eji protamine ma ọ bụ zinc eme ihe maka nke a.

Ogologo insulin

Ọgwụ nke otu a sitere na glargine - ihe yiri nke mmadụ, nke a na-enweta site na mmepe nke ọrụ mkpụrụ ndụ ihe nketa. Ọ bụ onyinye mbụ na-enweghị aha akpọrọ kachasi arụmọrụ. A na - enweta Glargine site na ụzọ isi degharịa ihe dị na agbụ DNA: gbanwee aspargin ka ọ bụrụ glycine, agbakwunye tinye akụkụ nke arginine.

A na-enweta insulin dabeere na Glargine dị ka ihe ngwọta doro anya na pH nke 4. Acid dị n'ime ya na - eme ka ahụ ọgwụ hexamers sie ike, na - enye aka na ọgwụ ogologo ọgwụ jiri nwayọọ nwayọọ na nwayọ nwayọ site na anụ ahụ. N'ihi nke a, enwere ike ịnye ya ego obere oge, ebe insulin na-achịkwa ogo nke glycemia ụbọchị niile.

N'adịghị ka ọgwụ ndị ọzọ, nke dị n'ọtụtụ dị iche iche n'ọbara, na-etolite ọnụ ọgụgụ kachasị elu nke ihe ahụ (ma, ya mere, jumps na glycemia), insulin na-adịte aka anaghị ekwupụta ụkpụrụ kachasị, ebe ọ bụ na ọ na-abanye na sistem n'ọtụtụ elele.

Ogologo insulin dị n'ọtụtụ usoro onunu ogwu nwere oge mmetụta hypoglycemic dị iche iche. Ná nkezi, ọgwụ ndị dị n'ụdị a na-achịkwa glucose n'ọbara maka awa 10-36. Adị ogologo oge dị otú a, yana ọgwụgwọ ọgwụgwọ, dabara adaba n'ihi na ọ na-azọpụta ndị ọrịa site na ịgba ntụtụ oge. Ọgwụ ndị ahụ dị n'ụdị mgbochi, nke ezubere maka ịnwe nchịkwa n'okpuru anụ ahụ ma ọ bụ intramuscularly.

Enweghị ike iji insulin rụọ ọrụ ogologo oge maka ọrịa shuga - coma, precom.

Ihe nnabata insulin

Nkwadebe dabere na ụdị insulin dị iche iche nwere njiri dị iche iche dị na ụdị nkwusioru. A na - enweta ihe ndị a jikọtara ọnụ n'ihi insulin na isophane dị mkpụmkpụ - obere oge iji rụọ ọrụ. Ngwakọta ndị dị otú a nwere ọnụego mgbakwunye dị iche iche na-enye ohere maka ngwa ngwa nchịkwa glycemic na ogologo oge nke ọnọdụ nkịtị.

Mmalite sitere

A na-ahọpụta ụdị insulin ọ bụghị naanị site na ọsọ nke ihe, oge nchịkwa glucose, mana ha dịkwa iche na mmalite. Ruo oge ụfọdụ, eji ọgwụ anụmanụ sitere anụmanụ eme ihe, yabụ, na mmepe nke sayensị, mmadụ, nke na - eme ka mma pụta.

Maka mmepụta nke insulin sitere na anụmanụ, a na-eji ihe ndị dịpụrụ adịpụ na pancreas ezì na anụ ụlọ. Enwere otutu ha di iche iche, ma ajuju nke ha kacha mara nke oma, a na-elebara ha anya na udiri ya. Ekwenyere na ndị kachasị dị mma bụ ndị nwere ntakịrị ọdịiche na okwu mmadụ.

A na-akwadebe nkwadebe insulin na-eme mmadụ. Drugsdị ọgwụ ndị a dị nso na ihe endogenous, mana n'ihi ihe ụfọdụ na DNA, ha nwere njiri dị iche iche. N'ihi ya, taa ndị dọkịta na-ahọrọ insulin nke ụdị a.

Kedu insulin ka mma - enweghị azịza doro anya maka ajụjụ a, ebe ndị ọkà mmụta sayensị na-arụ ọrụ na ọgwụ ọhụrụ, na-emepụta ọgwụ ndị ọzọ dị elu ma dị nchebe. N’agbanyeghi na enwebeghị mmeri ọrịa shuga, inyere ndị ọrịa aka ugbu a kachasị mfe. Taa, enwere ọtụtụ ọgwụ dị iche iche enwere ike iji ha abụọ ma chepụta atụmatụ nchịkwa dị iche iche site na iji insulin ngwa ngwa ma dị ogologo. Site n'enyemaka nke njikọta dị iche iche, ọnụ ọgụgụ buru ibu nke ndị ọrịa nwere ike juju afọ maka mkpa ha.

Rinsulin P: ụdị ntọhapụ na njirimara ọgwụ

Ọgwụ bụ insulin na-arụ ọrụ ngwa ngwa nke enwetara site na teknụzụ DNA. Ngwá ọrụ ahụ na-ekekọta ndị nabatara akpụkpọ anụ ahụ dị ná mpụga, na-akpụ insulin-receptor complex nke na-eme ka usoro ndị a na-adị n’ime mkpụrụ ndụ pụta, gụnyere imepụta enzymes na-eduga.

A na-enweta mbelata nke ọbara n’ọbara site n’ịbawanye ibu na-ebuga glucose n’etiti mkpụrụ ndụ, mmịkọta kpụ ọkụ n’ọnụ ya na nsị anụ ahụ na-esote. Mkpali nke glycogenogenesis, lipogenesis na-emekwa ma ọnụego ihe imeju na-emepụta site na imeju na-ebelata.

Dịka iwu, oge mkpebi mmetụta insulin na-ekpebi site na ọnụego nnabata, nke dabere n'ọtụtụ ihe (mpaghara yana ụzọ nchịkwa, dose). Ya mere, profaịlụ nke omume nwere ike ịdị iche na onye ọrịa ọ bụla. Mana tumadi mgbe nchịkwa subcutaneous gasịrị, Rinsulin P na-eme mgbe ọkara elekere gasịrị, a na-enwekwa nsonaazụ kachasị mgbe awa 1-3 gachara, wee rue awa 8.

GEROFARM-BIO OJSC onye na-emepụta insulin na-emepụta ọgwụ ahụ n'ụdị atọ:

1. Ngwọta (10 IU / ml) maka ogwu ogbugba nke 3 ml nke ọgwụ na katrized iko na ngwa nkwanye roba.
2. 5 katọn dị na ngwungwu nke blil na PVC.
3. A na-etinye katalọgụ n'ime mkpịsị mkpịsị nke nwere mkpịsị ugwo nke nwere plastik, etinye ya na igbe kaadi.

Oke nke nnabata na nnabata nke insulin na-eme ihe mmadụ na-ekpebi bụ mpaghara, ebe, ụzọ nchịkwa na itinye uche nke ihe eji arụ ọrụ. E kesaghị ọgwụ ahụ n’erụ anụ ahụ niile, ọ banyeghị n’ime mmiri ara ara yana ihe mgbochi placental.

Site na insulinase mebiri emebi na akụrụ ya na imeju. Ọgwụ dị na 30-80% nke akụrụ. T1 / 2 bụ nkeji 2-3.

Ntuziaka maka iji ọgwụ ahụ

A na-egosi ọgwụ ahụ maka ụdị ọrịa shuga ọ bụla, n'ọnọdụ nke iguzogide ma ọ bụ nke zuru oke na mbadamba shuga dị ala. A na-ejikwa ya n'ọnọdụ ọnọdụ mberede na ndị ọrịa mamịrị megide nzụlite decompensation nke carbohydrate metabolism yana gbasara ọrịa oria. Agbanyeghị, ọgwụ a ka enyeghị ọgwụ hypoglycemia na mmadụ ịhapụ ihe ya.

Emere ogwu a maka iv, v / m, s / c management. Uzo uzo ochichi na usoro onunu ogwu a bu ndi ndi endocrinologist debere ya dabere na njiri mara onye ọrịa. Ogologo ogwu ahu bu 0-1-1 IU / n'arọ.

A na-enye ọgwụ insulin na-adị mkpụmkpụ n'ime nkeji iri atọ. tupu ị foodsụ nri carbohydrate. Mana buru ụzọ, ị ga-eche ruo mgbe ọnọdụ okpomọkụ nke nkwusioru ahụ rutere opekata mpe 15.

N'ihe banyere monotherapy, a na-ahụ insulin ugboro atọ ruo ugboro isii kwa ụbọchị. Y’oburu na ubochi ubochi kariri 0.6 IU / kg, yabụ ikwesiri itinye abali abuo ma obu karie n’ebe di iche.

Dịka iwu, a na-agbanye ihe nnọchianya ahụ n'ime mgbidi afọ. Ma inje nwekwara ike ịme ya n’ubu, ihe mkpuchi na apata ụkwụ.

Site n'oge ruo n'oge, a ga-agbanwe mpaghara ntụtụ, nke ga-egbochi ọdịdị nke lipodystrophy. N'ihe banyere homonụ subcutaneous nke homonụ, ịkwesịrị ịkpachara anya iji hụ na mmiri mmiri abanyeghị na ọbara ọbara. Ọzọkwa, mgbe ịgba ntụtụ, a gaghị enwe ike ịhịa aka ntụtụ.

Na nchịkwa / m na / m ga-ekwe omume naanị n'okpuru nlekọta ahụike. A na-eji katridges naanị ma ọ bụrụ na mmiri mmiri nwere acha ọcha na-enweghị mmerụ, yabụ, mgbe mgbasa ozi gosipụtara, ekwesighi iji ya.

Ọ dị mma icheta na katriki ndị ahụ nwere ngwaọrụ arụpụtara nke anaghị anabata ịgwakọta ọdịnaya ha na ụdị insulin ndị ọzọ. Mana iji ndozi zuru oke nke mkpụrụ sirinji enwere ike ijighachi ha.

Mgbe etinyere ya, a ga-ejikọrịrị agịga ahụ na okpu mpụta ya wee tụfuo ya. Yabụ, enwere ike igbochi mmiri ọsụsọ, enwere ike ịnwe mmerụ ahụ, ikuku enweghị ike ịbanye na agịga ahụ wee kechie.

Mgbe ị na-eji mkpịsị mkpụrụ ọgwụ mịrị amị nke jupụtara, were sirinji si na friji tupu i buru ụzọ jiri chere mgbe ọ ga-eru ọ̀gele. Agbanyeghị, ọ bụrụ na mmiri mmiri agbajila ma ọ bụ nwee urukpuru, mgbe ahụ enweghị ike iji ya.

Iwu ndị ọzọ ka kwesịrị ịdị mkpa:

• Enweghi ike iji ya ọzọ,
• A na-ezube insulin P nke edere sirinji maka iji ya mee ihe naanị, ebe a na-enweghị ike ịjuju kaịlị pen sirinji,
• agaghị echekwa mkpụrụ sirinji eji friji,
• iji kpuchido mkpịsị ọpịpị site na ọkụ, jiri okpu kpuchie ya mgbe niile.

Ọgwụ a ejirila mee ihe kwesịrị ịchekwa ya n ’ọnọdụ okpomọkụ nke ogo 15 ruo 25 n’erughi ụbọchị 28. Ọzọkwa, ekwesighi ịhapụ ngwaọrụ ikpo ọkụ ma kpughere ya ìhè anyanwụ.

N'ihe banyere ịdoụbiga ọbara ókè, ịbara shuga nwere ike ibelata nke ukwuu. Ọgwụ hypoglycemia gụnyere ị foodsụ nri nwere carbohydrate ma ọ bụ ihe ọ drinkụ sweetụ dị ụtọ. Ya mere, ndị na-arịa ọrịa shuga kwesịrị ịnwe ha ọsụsọ ma ọ bụ ihe ọ juiceụ juiceụ mgbe niile

N’okpo hypoglycemia dị ukwuu, mgbe onye ọrịa mamịrị na-amaghị onwe ya, a na-eji mmiri glucose na-egbu ya (40%) ma ọ bụ glucagon.

Mgbe mmadụ nwetasịrị onwe ya, ekwesịrị inye ya nri carbohydrate, nke ga-egbochi mmepe nke mwakpo nke abụọ.

Mmeghachi omume Ọjọọ na Mmekọrịta Ọgwụ

Mmetụta ndị ọzọ bụ ọdịda nke metabolism metabolism. Ya mere, nyocha nke ndị dọkịta na ndị ọrịa na-agbadata n'eziokwu ahụ na mgbe nchịkwa Rinsulin P gasịrị, hypoglycemia nwere ike ịmalite. E gosipụtara nke a site na ịrịa ọrịa, ịcha ahụ nke anụ ahụ, isi ọwụwa, nkwonkwo, ịma jijiji, agụụ, hyperhidrosis, dizzness, na n'ọnọdụ ndị siri ike, hypoglycemic coma na-amalite n'ọrịa shuga mellitus.

Mmeghachi omume nfụkasị, dị ka ụbụrụ Quincke, ụzarị akpụkpọ, bụkwa ekwe omume. Ọrịa anaphylactic, nke nwere ike ibute ọnwụ, na-amalite mgbe ụfọdụ.

Site na mmeghachi omume mpaghara, itching, ọria na hyperemia na ntụtụ na-abụkarị. N'ihe banyere ọgwụ insulin ogologo oge, lipodystrophy na-apụta na ebe ịgba ọgwụ.

Mmeghachi omume ndị ọzọ na-adịghị mma na-agụnye ọzịza na nkwarụ anya. Mana ọtụtụ mgbe, mgbaàmà ndị a na-apụ n'oge ọgwụgwọ.

Enwere ọtụtụ ọgwụ na-emetụta chọrọ insulin. Yabụ, nyocha nyocha ahụike na-ekwu na ọsụsọ ike insulin na-esikwu ike ma ọ bụrụ na ejikọ ya na usoro ndị a:

1. Mbadamba hypoglycemic,
2. ethanol
3. ACE / MAO / carbonic anhibidose inhibitors,
4. nkwadebe lithium
5. ndị na-abụghị ndị a na-ahọta,
6. Fenfluramine,
7. Bromocriptine
8. Cyclophosphamide,
9. salicylates,
10. Mebendazole na ndị ọzọ.

Nicotine, glucagon, phenytoin, somatropin, morphine, estrogens, ọgwụ mgbochi ede, diazoxide na corticosteroid na-ebelata mmetụta hypoglycemic. Homonụ thyroid nwere iodine, CCB, thiazide diuretics, Epinephrine, Clonidine, Heparin, Danazole, tricyclic antidepressants na sympathomimetics na-akụda ike iwelata shuga.

Ojiji B-blockers nwere ike kpuchie ihe ịrịba ama nke hypoglycemia. Lanreotide ma ọ bụ Octreotide na mmanya nwere ike ịbawanye ma ọ bụ wedata insulin chọrọ.

Ọ bụ ekwekọrịtaghị kpamkpam ịgwakọta insulin mmadụ na ọgwụ ndị ọzọ na ngwaahịa anụmanụ.

Ntụziaka pụrụ iche

Na-emegide usoro ọgwụgwọ insulin, ọ dị mkpa iji nyochaa ndị na-egosi glycemia mgbe niile. N’ezie, na mgbakwunye na ịdoụbiga mmanya ókè, ọrịa ụfọdụ, iji ọgwụ dochie anya, ịba ụba nke anụ ahụ, afọ ọsịsa, mgbanwe na ntụtụ yana ọbụna nri na-adịghị egbu oge nwere ike itinye aka na belata shuga shuga.

Na mgbakwunye, nkwụsị nke nchịkwa insulin na usoro na-ezighi ezi nwere ike ibute ọrịa hyperglycemia na ndị ọrịa nwere ụdị shuga 1. Na enweghị ọgwụgwọ, ketoacidosis na-egbu ndụ nwere ike ịmalite.

Ọ bụrụ na enwere mmebi na arụ ọrụ nke akụrụ, imeju, glandia gland, hypopituitarism, ọrịa Addison na mgbe ị mere agadi, ọ dị mkpa ka ịhazigharị ọgwụ insulin. Na mgbakwunye, mgbanwe nke usoro onyonyo nwere ike ịdị mkpa mgbe ị na-agbanwe nri na ịba ụba nke mmega ahụ.

Mkpa insulin na-abawanye ebe ọnụnọ ndị na-efe efe, ọkachasị ndị na-efe efe. Ọ dị mma ịmara na n'oge mgbanwe site na ụdị insulin gaa na nke ọzọ, ị kwesịrị iji nlezianya nyochaa shuga ọbara.

Ọnụ ego Rinsulin P sitere na 448 ruo 1124 rubles.

Na mgbakwunye na Insulin P, enwere ọgwụ Rinsulin NPH. Mana olee otu esi enweta ego ndia?

Rinsulin NPH

Ọgwụ ahụ bụkwa insulin nke mmadụ nwetara site na teknụzụ DNA recombinant. Agbanyeghị, ma e jiri ya tụnyere Insulin P, ọ bụghị ihe dị mkpụmkpụ, mana ọ na-enwe mmetụta dị nta. Enwere ike ijikọ ọgwụ abụọ a.

Dịka iwu, mgbe nchịkwa sc, ihe insulin na-amalite mgbe awa 1.5 gachara. A na - enweta nsonaazụ kasịnụ mgbe awa 4-12 gachara, ọ na - adịgide otu ụbọchị.

Nchupu ahụ nwere agba ọcha, ma mgbe a na-eguzoro na ala karama ahụ, a na-ebugharị ụdị mkpali, nke, mgbe ọ na-ama jijiji. Ihe na-arụ ọrụ nke ọgwụ ahụ bụ insulin-isophan.

A na - eji ihe inyeaka eme ihe:

• mmiri anya mmiri
• Promina Nwepu
• ikuku sodium hydrogen phosphate na-ada mmiri,
• glycerol
• metacresol
• crystalline phenol.

Nkwụsị ahụ dị na katrized iko nke milimita atọ ọ bụla, etinye ya na mkpọ katọn. Ọzọkwa, enwere ike ịzụta ngwaahịa ahụ na katrized iko etinyere na ntụtụ ọnụọgụ maka ọtụtụ injections nke Rinastra.

Pharmacokinetics na ngosipụta maka iji ọgwụ ahụ bụ otu ihe ahụ maka ojiji nke Rinsulin R. Ọ bụ dọkịta na-ekpebi usoro ị theụ ọgwụ ahụ.

Nkezi ọgwụ a bụ 0-1-1 IU / n'arọ nke ogo ahụ. Ma mgbochi intravenous nchịkwa bụ contraindicated.

Ntuziaka maka iji Rinsulin NPH banyere nsonaazụ ndị ọzọ, ịdoụbiga akụrụngwa na ụzọ iji eme ihe adịghị iche na nkọwapụta insulin mmadụ na-eme mkpụmkpụ.

Ọnụahịa nke nkwusioru ahụ sitere na 417 ruo 477 rubles. Vidio dị n’isiokwu a ga-enyere gị aka ịmụ ka e si edozi insulin.