Tsifran ST, mbadamba 500 mg 600 mg, 10 PC

Edere “Tsifran” maka ọrịa ndị na-esote: ọrịa nke sistem mkpụrụ ndụ (akwara na ọrịa pyelonephritis, cystitis, prostatitis, epididymitis), ọrịa na-efe efe (bronchoponiaonia, poniaonia, exacerbations of bronchiitis, nnukwu bronchitis, pleurisy, lung efits, proyema), gonorrhma, , urethritis, ọrịa nke akụkụ ENT (nke etiti na nke mpụga otitis media, sinusitis, mastoiditis), ọrịa nke anụ ahụ na anụ ahụ dị nro (ọkụ, ọnya, ọnya na ọnya afọ), ọrịa afọ na-efe efe (peritonitis, fever typhoid, cholangitis), ọrịa anụ ahụ na ọrịa na-efe efe. obere pelvis (endometritis, salpingitis), na-efe efe nke nkwonkwo na ọkpụkpụ.

Ọ bụ dọkịta ga-edozita oge na ọgwụgwọ nke "Tsifran", n'otu n'otu n'ọnọdụ nke ọ bụla, dabere n'ịdị ọcha nke ọrịa ahụ, ihe nchọpụta ahụrụ, afọ onye ọrịa, oke ahụ yana ọrụ akụrụ. Maka umuaka site na afo iri na abuo “Tsifran” ka enyere ka ubochi nke 5-10 mg kwa otu kilogram nke aru aru, nke kewara uzo ato. E kwesịrị iburu mbadamba tupu nri. A na-elekọta ndị okenye "Tsifran" n'ọbara (nwayọ nwayọ) n'ụdị infusus na ọnụọgụ 200 mg ugboro abụọ kwa ụbọchị maka ọrịa nke akwara na akụkụ ahụ. Maka ọrịa ndị ọzọ, a na-a theụ ọgwụ ahụ na 200 mg na nkeji nke awa 12. N'ọnọdụ arụ ọrụ ezumike, a na-ebelata ọgwụ kwa ụbọchị site ugboro abụọ. N'ọnọdụ ụfọdụ, mgbe nchịkwa gọọmentị gasịrị, ha na-agbanye na nchịkwa ọnụ nke ọgwụ. A na-eme ọgwụgwọ maka ọrịa na-efe efe dịkarịa ala ụbọchị 5-7. Mgbe mgbaàmà ahụ kwụsịrị, a na-agbatị usoro ahụ ruo ụbọchị 3 ọzọ.

Nsonaazụ na contraindications iji "Tsifran"

“Tsifran” nwere ike ibute nsonaazụ dịka flatulence, vomiting, ọgbụgbọ, mgbu afọ, ịba ọcha n'anya, isi ọwụwa, paresthesia, ọgbụgbọ, mgbakasị ahụ, mgbagha, mgbakasị ahụ, migraine, oke nke oke ahụ, ọhụhụ ụzọ, isi, uto, obi ọgbụgba obi. , eosinophilia, leukopenia, leukocytosis, anaemia, thrombocytosis, hemolytic anemia, ọrụ na-abawanye nke enzymes imeju, hyperglycemia, hematuria, glomerulonephritis, dysuria, polyuria, njigide nke urinary, urethral ọbara, myalgia, arthralgia, arthralgia, arthralgia yarns, ogbu na nkwonkwo, akaị agbawa, pseudomembranous afọ, candidiasis, generalized adịghị ike.

A na - egbochi ọgwụ ọgwụ maka ọgwụ hypersensitivity ya, n'oge afọ ime na lactation, nye ụmụaka na-erubeghị afọ iri na abụọ. Site na nlekọta pụrụ iche, a na-eji “Tsifran” mee ihe na ndị nwere nnukwu ngosipụta nke ụbụrụ arteriosclerosis, yana ihe ọghọm nke ọrịa ụbụrụ, ọrịa uche, àkwụkwụ na-adọ, ọrịa imeju, imeju na / ma ọ bụ ọdịda akụrụngwa, na nká.

Emeputa

Mbadamba ụrọ gbara agba nwere
bekee na-arụ ọrụ: ciprofloxacin hydrochloride USP, nke ruru kaproprololoxacin 500 mg, tinidazole BP 600 mg,
ndị na-ahụkarị: microcrystalline cellulose, silloon colloidal annesrous, magnesium stearate, sodium starch glycolate, sodium lauryl sulfate. Ihe mejupụtara nke mpụta akwa nke granules: sodium sitashi glycolate, talc ọcha, sodium lauryl sulfate, microcrystalline cellulose, colloidal anhydrous silicon, magnesium stearate. Shell: Opadry edo edo, mmiri dị ọcha.

Omume ọgwụ

Mlọ ọgwụ
Tsifran ST bụ nkwadebe ejikọtara maka ọgwụgwọ nke ọrịa nje jikọtara ọnụ nke anaerobic na microorganisms, yana ọrịa nke eriri afọ, dịka ọmụmaatụ, afọ ọsịsa ma ọ bụ ọnyụnyụ ọbara, amoebic ma ọ bụ nje (amoebic na nje). Tinidazole dị irè megide microorganisms anaerobic dị ka Clostridium difficile, Clostridium perfringens, Bacteroides fragilis, Peptococcus na Peptostreptococcus anaerobius. Microorganisms anaerobic na - ebute ọrịa nke oghere afọ, pelvis, ngụgụ, ma ọ bụ akụkụ ahụ nke ọnụ. Mgbe anaerobic na-efe efe, ọtụtụ mgbe, enwere ngwakọta nke nje anaerobic na nje aerobic. Ya mere, na ọrịa anaerobic agwakọta, ọgwụ nje na-arụ ọrụ megide nje aerobic na-agbakwunye na usoro ọgwụgwọ ahụ.

Ciprofloxacin bụ ọgwụ nje sara mbara nke ọtụtụ ọgụ aerobic gram-nke oma na gram-negative microorganisms dịka E. coli, Klebsiella spp., S.typhi na ụdị Salmonella, P.mirabilis, P.vulgaris, Yersinia enterocoilitica, Ps.aeruginosa, Shigella flexneri, Shigella sonnei, H.ducreyi, H.influenzae, N..gonorrhoeae, M. catarrhalis, V. cholerae, B. fragilis, Staph.aureus (gụnyere methicillin strains na-eguzogide ọgwụ), Staph.epidermidis, Strep.pyogenes, Strep. oyi baa, Chlamidia, Mycoplasma, Legionella, na ụkwara nta Mycobacterium.

Mlọ ọgwụ
Ma ciprofloxacin na tinidazole na-etinye obi gị dum na eriri afọ. A na-enweta oge ọgụgụ kachasị elu nke ihe ọ bụla n'ime awa 1 ruo 2. Nzube zuru oke nke tinidazole bụ 100%, yana ịmịkọta protein na plasma bụ 12%. Iwepu ọkara ndụ bụ ihe dịka awa 12-14. Ọgwụ na-abanye ngwa ngwa nke anụ ahụ, na-erute nnukwu ebe ahụ. Tinidazole banye n'ime mmiri akụkụ akwara ya na mkpo ya na ịhe plasma ma na-enwetakwa ntụgharị n'ime akwara gbasara akịrị. Tinidazole dị na bile na mkpụmkpụ obere karịa 50% nke ịta ya na plasma. Ihe dị ka 25% nke ọgwụ aere na-apụtaghị na mmamịrị ahụ.

Metabolites mejuputara 12% nke usoro nchịkwa ma na-apụtakwa na mmamịrị. Na nke a, enwere ntakịrị ihe ga - eme ka tinidazole ya na ọnya afọ.
Ciprofloxacin na-etinye obi gị dum na nchịkwa ọnụ. Bioavailability nke ciprofloxacin bụ ihe dịka 70%. Mgbe ejikọtara ya na nri, ị theụ nri nke ciprofloxacin na-akwụsịlata. 20-40% nke ọgwụ na-egbochi protein ndị dị na plasma. Ciprofloxacin na-abanye nke ọma na mmiri na anụ ahụ: akpa ume, anụ ahụ, abụba, akwara na akwara, yana akụkụ ahụ na urinary, gụnyere prostate. A na-ahụ ọgwụ ahụ n'ọtụtụ ugwu na mmiri, imi n'ime oghere imi ya na bronchi, spam, lymph, mmiri peritoneal, bile na prostate secretion. Ciprofloxacin na-mejupụtara akụkụ imeju ya. Ihe dị ka 50% nke ọgwụ a isụrụ na-apụ apụ na mmamịrị, yana 15% n'ụdị metabolites na-arụ ọrụ, dị ka oxociprofloxacin. Fọm nke fọrọnụ ka ọpịputere na bile ahụ, na-agbadata akụkụ ya ugboro ugboro. Ihe dị ka 15-30% nke ciprofloxacin bụ ihe dị na feces. Oge ikpochapu ọkara ndụ bụ ihe dịka awa 3.5-4.5. Enwere ike ịgbatị ndụ ọkara ọkara ogologo oge na nnukwu ọrịa gbasara akụrụ na ndị ọrịa meworo agadi.

• Ekwuru na Tsifran ST maka ọgwụgwọ nke ọrịa ndị a:
• Ofgwọ ọrịa nje dị iche iche kpatara site na nchekasị anaerobic na microorganisms: ala ala sinusitis, ọnya afọ, empyema, intra-abdominal ofufe, ọrịa mkpali, ọrịa na-efe efe mgbe ọnụnọ aerobic na nje anaerobic, osteomyelitis na-adịghị ala ala, anụ ahụ na adụ anụ ahụ, ọnya na ọrịa shuga. ụkwụ ”, ọnya ọgbụgba, ọrịa nke ọnya ọnụ (gụnyere peridontitis na periostitis).
• Ọgwụ ọgbụgba ma ọ bụ ọnyụnyụ nke amoebic ma ọ bụ ọgwụ etiology (ọgwụ nje na nje).

Ime na lactation

A naghị atụ aro iji Cyfran CT n'oge afọ ime. Tinidazole nwere ike uto carcinogenic na mutagenic. Ciprofloxacin na-agafe mgbochi mgbochi hematoplacental. Ojiji nke tsifran ST bụ nke a na-enye n'oge ara. Tinidazole na ciprofloxacin na-apụ apụ na mmiri ara. Yabụ, n'oge a na-enye nwa ara, ọ bụrụ na ọ dị mkpa iji Tsifran ST, a ga-akwụsị inye ara ya.

Ihe ngbanwe

• A na - eke ọgwụ Cifran ST na ndị ọrịa nwere ọgwụ ike (allergy) na usoro ọ bụla nke fluoroquinolone ma ọ bụ imidazole.
• A na - egbochikwa Tsifran ST na ndị ọrịa nwere ọrịa hematologic. Na mgbochi nke ụmị ọkpụkpụ, nnukwu porphyria.
• A na - egbochi Tsifran ST na ndị ọrịa nwere ọnya ọnya akwara.
• A na - egbochi Tsifran ST na ndị ọrịa nwere obere ụmụaka (ruo afọ 18).

Jiri nlezianya
Ekwesịrị iji ọgwụ ahụ mee ihe na ịkpachara anya na ndị ọrịa nwere nnukwu atherosclerosis nke arịa ụbụrụ, yana ihe ọghọm nke ọrịa ụbụrụ, yana ọrịa uche, arịa akwụkwụ, na-arịa ọrịa akwụkwụ, nnukwu akụrụ na / ma ọ bụ imeju.
Mgbe ị na-eji ọgwụ ahụ eme ihe na ndị agadi, enweghị nsogbu ọ bụla akọwapụtara. Agbanyeghị, na ndị ọrịa merela agadi, mbelata afọ maka ọrụ akụrụ ga-ekwe omume, yabụ ekwesịrị ịkpachara anya mgbe ị na-eji ọgwụ ahụ na ndị ọrịa dị otú ahụ.

Nsonaazụ

Site na usoro nri: belata agụụ, mucosa a na-ede ede, “ihe otite” n’ọnụ, ọgbụgbọ, ọgbụgbọ, afọ ọsịsa, ọnya afọ, flatulence, cholestatic jaundice (ọkachasị ndị ọrịa nwere ọrịa imeju gara aga), ịba ọcha n’anya, ịba ọcha n’anya.
Site na usoro ụjọ ahụ: isi ọwụwa, dizzness, ike ọgwụgwụ, nhazi nke mmegharị (gụnyere locomotor ataxia), dysarthria, neuropathy na-adịghị ala ala, ụfụ na-adịghị ike, adịghị ike, ịma jijiji, ehighị ụra nke ọma, ịza ụba, ịba ụba mgbali intracranial, ọgba aghara, ịda mba, hallucinations, yana ngosipụta ndị ọzọ nke mmeghachi omume psychotic, migraine, nkụda mmụọ, thrombosis akwara.
N’akụkụ akụkụ anụ ahụ nke anụ ahụ, uto na isi adịghị mma, ọhụhụ ụzọ (diplopia, mgbanwe n’ichepụta ụcha), tinnitus, ụfụ ịnụ.
Site na sisitemu obi: tachycardia, cardiac arrhythmias, mbelata obara obara.
Site na usoro hematopoietic: leukopenia, granulocytopenia, anaemia, thrombocytopenia, leukocytosis, thrombocytosis, hemolytic anemia
N'akụkụ nke ihe ngosipụta ụlọ nyocha: hypoprothrombinemia, ụba ọrụ nke “transminases imeju” na alkaline phosphatase, hypercreatininemia, hyperbilirubinemia, hyperglycemia
Site na sistemụ urinary: hematuria, crystalluria (mmamịrị alkaline na mmepụta mmamịrị dị ala), glomerulonephritis, dysuria, polyuria, njigide urinary, belatara ọrụ ọrụ excretory nke akụrụ, mbelata nke nephritis interstitial.
Mmeghachi omume nfụkasị: itching, hives, guzobe blisters tinyere ọbara ọgbụgba, na ọdịdị nke obere nodules na-akpụ scabs, fever fever, hemorrhages ntụpọ (petechiae), ọnya ihu ma ọ bụ ogwooro, mkpụmkpụ nke iku ume, eosinophilia, mụbara photoensitivity, vasculitis, nodular erythema multiforme exudative (gụnyere Stevens-Johnson ọrịa), necrolysis na-egbu egbu (ọrịa Lyell).
Ndị ọzọ: ogbu na nkwonkwo, ogbu na nkwonkwo, tendovaginitis, tendon ruptures, asthenia, myalgia, superinfection (candidiasis, pseudomembranous colitis), iwepu ihu.

Mmekorita

Tinidazole
Na - eme ka mmetụta anticoagulants na - apụ apụ (iji belata ihe ọ bụla na - agba ọbara, a na - ebelata 50%) yana ihe ethanol (mmeghachi omume disulfiram).
Dakọtara na sulfonamides na ọgwụ mgbochi (aminoglycosides, erythromycin, rifampicin, cephalosporins).
Achọghị ka etinyere ya na etionamide.
Phenobarbital na-eme ka metabolism dị ngwa.
Ciprofloxacin
N'ihi mbelata nke ọrụ microsomal oxidation Filiks na hepatocytes, ọ na-eme ka ịta ahụ dịkwuo ma na-agbatị ndụ ọkara nke theophylline (na xanthine ndị ọzọ, dịka ọmụmaatụ caffeine) nke ọgwụ hypoglycemic ọgwụ (PM), anticoagulants na-apụtaghị ìhè, ma na-enyere aka belata ndepụta prothrombin.
Mgbe ejikọtara ya na ọgwụ mgbochi ọgwụ ndị ọzọ (ọgwụ beta-lactam, aminoglycosides, clindamycin, metronidazole), a na-ahụkarị synergism.
Na-akwalite mmetụta nephrotoxic nke cyclosporrin, a na-achọpụta mmụba na serin creatinine, na ndị ọrịa dị otú a, ọ dị mkpa igosipụta akara a ugboro abụọ n'izu.

N'otu oge ahụ, ọ na-eme ka mmetụta nke anticoagulants na-apụtaghị ìhè pụta ìhè.
Nlekọta ọnụ na Fe nwere ọgwụ, sucralfate na ọgwụ antacid nwere Mg2 +, Ca2 +, A13 + na-eduga n'ịbelata mmịkọta nke ciprofloxacin, yabụ ekwesịrị ịkọ ya 1-2 awa tupu ma ọ bụ 4 awa mgbe ị drugsụsịrị ọgwụ ndị ahụ dị n'elu.
Ọgwụ mgbochi ọrịa anti-inflammatory nonsteroidal (ewezuga acetylsalicylic acid) na-abawanye ohere nke ọdụdọ.
Didanosine na -ebelata nnabata nke ciprofloxacin n'ihi ịmepụta ihe dị mgbagwoju anya na ya, nke nwere Mg2 +, A13 + dị na didanosine.
Metoclopramide na-agbakwu ngwa ngwa, nke na-eduga n'ịbelata oge iji ruo na ntinye uche kachasị.
Njikọ aka nke ọgwụ uricosuric na-eduga n'ibelata mkpochapụ (ihe ruru 50%) na mmụba na mkpokọta plasma nke ciprofloxacin.

Dodoụbiga ya ókè

Enweghị ọgwụ mgbochi akọwapụtara, yabụ, ịgwọ ọrịa ọgwụ ịfụbiga oke ókè nke Cyfran CT kwesịrị ịbụ Symptomatic ma gụnye usoro ndị a:
- Itọgide ọgbụgba ma ọ bụ ọnya afọ.
- Iwere nha iji nweta mmiri zuru oke nke ahụ (ọgwụ infusion).
- Nkwado na-akwado.

Ntụziaka pụrụ iche

A na-atụ aro ka ọ ghara ịhapụ ịcha ọkụ mgbe anwụ na Cifran ST, ebe ọ bụ na ụfọdụ ndị ọrịa mesoro fluoroquinolones nwere mmeghachi omume phototoxicity. Ọ bụrụ na mmeghachi ọgwụ phototoxicity mere, kwụsị ị useụ ọgwụ ahụ ozugbo.
Mgbe ị na-eji tinidazole, ọ ga-ekwe omume (mana ọ dị ụkọ) ịmalite urticaria juputara, mgbu nke ihu na akwara, belata ọbara mgbali, bronchospasm na dyspnea. Ọ bụrụ na onye ọrịa ahụ nwere ihe nfụkasị maka ihe ọ bụla dị n'ụdị iridazole, mgbe ahụ, ịkpa ike na tinidazole nwere ike ịmalite, mmepe nke mmeghachi omume nfụkasị nri na ciprofloxacin ga-ekwe omume na ndị ọrịa nfụkasị ikike ndị ọzọ fluoroquinolone. Ya mere, ọ bụrụ na onye ọrịa nwere mmeghachi omume nfụkasị ọ bụla maka ọgwụ ndị yiri ya, enwere ike ịtụle ohere nke nfụkasị ahụ na Cyfran ST.
Site na iji tinidazole na mmanya na-eme ihe, ihe na-egbu mgbu afọ, ọgbụgbọ na ọgbụgbọ pụrụ ịmalite. Yabụ, ojiji ejikọtara Cifran ST na mmanya na-egbu egbu.

Iji zere mmepe nke kristal, ọgwụ a na-atụ aro kwa ụbọchị ekwesịghị ịgabiga, mmiri zuru oke na ntinye nke mmeghachi mmamịrị acidic dịkwa mkpa. Na-akpata mmachi nke mmamịrị gbara ọchịchịrị.
N'oge ọgwụgwọ, ị kwesịrị ịhapụ itinye aka n'ihe omume dị egwu nke chọrọ nlebara anya na ọsọ nke mmeghachi omume nke uche na moto.
Ndị ọrịa nwere ọrịa akwụkwụ, akụkọ ihe mere eme nke ọdịdọ, ọrịa vaskụla na ọnya ụbụrụ organic, n'ihi ihe egwu nke mmeghachi omume akwara site na sistemụ akwara etiti, a ga-ede ọgwụ ahụ naanị maka ngosipụta "dị mkpa".
Ọ bụrụ na afọ ọsịsa ọria na-adịte aka ma ọ bụ mgbe ọ gachara ọgwụgwọ, ekwesịrị ị wepu nchoputa nke pịudomembranous colitis, nke chọrọ iwepụ ọgwụ ozugbo na ịhọpụta ọgwụgwọ kwesịrị ekwesị.
Site na ngosipụta nke ihe mgbu na akwara ma ọ bụ mmalite nke ihe ịrịba ama mbụ nke tenosynovitis, a ga-akwụsị ịgwọ ya.
N'oge ọgwụgwọ, o kwesịrị inyocha onyonyo nke ọbara mgbakwunye.
Emebebeghị nchekwa na nrụpụta ọrụ maka ọgwụgwọ na mgbochi nke ọrịa anaerobic n'ime ụmụaka na-erubeghị afọ 12.

Mpempe usoro onunu ogwu

Mbadamba ihe eji etinye fim, 500 mg

Otu mbadamba ihe

ike ihe - ciprofloxacin hydrochloride 582.37 mg (nke kwekọrọ na ciprofloxacin) 500.00 mg

ndị mgbe ochie: microcrystalline cellulose (Avicel PH101), ọka ọka, stachi ọka (maka gluing), magnesium stearate, talc, anhydrous colloidal silicon dioxide, sodium starch glycolate (ụdị A), mmiri dị ọcha.

Shei: mmiri dị ọcha, opadry OY-S-58910 ọcha (hypromellose E464, titanium dioxide E171, polyethylene glycol 400, talc E553

Mbadamba ụrọ chakọtara ekpuchi nke nwere ihe nkiri nwere mkpuchi si acha ọcha ruo ihe fọrọ nke nta ka ọ bụrụ ọcha, nke a kanyere na "500" n'otu akụkụ ma dị mma n'akụkụ nke ọzọ.

Ngwongwo ogwu

Mlọ ọgwụ

Mgbe nchịkwa ọnụ gachara, a na-enweta mkpụrụ ndụ nkeproprololoacin ngwa ngwa site na obere eriri afọ nke mgbago, na-erute mkpokọta ọbara (Cmax) mgbe nkeji 60-90 gachara. Nri adighi emetuta ogo igba ogwu a. Mgbe ị takingụsịrị otu ọgwụ 250 mg na 500 mg, Cmax bụ 0.8-2.0 mg / L na 1.5-2.9 mg / L, n'otu n'otu. Ezigbo bioavailability bụ 70-80%. Cmax nwere akara sitere linear on the dose take.

Olu nke nkesa nkeproprololoacin bụ 2-3 l / n'arọ, nke na-eme ka edobere nkesa ihe niile na anụ ahụ. Ebe ọ bụ na ogo nke ijikọ protein na plasma bụ naanị 20-30% na ọtụtụ ọgwụ a ka egosipụtara na plasma n'ụdị na-abụghị ionized, ihe fọrọ nke nta ka ọ bụrụ dum ọgwụ a na-ewere n'ụdị na-enweghị atụ na-ekesa n'ime oghere vaskụla.

Ọ bụ metabolized na imeju. Iwepu ọkara ndụ na-eme awa 3-5. Ọ bụ ihe dịkarịsịrị adị na mmamịrị, akụkụ ya n'ụdị metabolites. Ihe dị ka 10% dị na eriri afọ ya, ọ na-adị ihe dị ka 1% nke ciprofloxacin na bile.

Pharmacokinetics na otu ọrịa ọrịa pụrụ iche. Nsonaazụ nke ihe omumu nke pharmacokinetic nke ciprofloxacin na ndi ọrịa merela agadi na-egosi obere ogologo oge nke ọkara. Ndi iche a na pharmacokinetics abughi ihe di egwu..

Ọdịda ya. N'ime ndị ọrịa nwere ọrụ mkpolata mgbadata, ọkara ndụ ciprofloxacin dị ogologo oge. N'ọnọdụ ụfọdụ, enwere ike ịchọ mgbanwe iji usoro onunu ogwu..

Imeju imeju. Na omumu mbu banyere ndi ọrịa nwere nsogbu imeju aria, enweghi mgbanwe di egwu na ọgwụ pharmacokinetic nke ciprofloxacin. Agbanyeghị, ọgwụ pharmacokinetics nke ciprofloxacin na ndị ọrịa nwere ọrịa imeju na-agacha nke ọma.

Mkparịta ụka ọgwụ na ọgwụ. N'ihe banyere ị tabletsụ mbadamba mkpụrụ osisi ciprofloxacin n'otu oge, nri, nnabata nke ọgwụ ahụ na-agbadata, n'ihi nsonaazụ kachasị nke ciprofloxacin n'ọbara ruru mgbe ihe dị ka elekere abụọ gachara, ọ bụghị mgbe awa 1 gachara. N'otu oge ahụ, a na-anyụcha mmiri nke ciprofloxacin n'ozuzu ya. Mgbe ejikọtara ya na antacids nwere magnesium ma ọ bụ aluminom hydroxide, enwere ike belata bioavailability nke ciprofloxacin 90% .

A na-egbochi Ciprofloxacin na ndị ọrịa na-anata tizanidine.

Ciprofloxacin na -ebelata mwepu theophylline, nke nwere ike ibute mmụba n'ọbara nke theophylline na-abawanye ma nwekwuo ihe egwu nke nsogbu ụjọ akwara na nsogbu ndị ọzọ. Ciprofloxacin na -ebelata mwepu nke caffeine ma gbochie e guzobe ya metabolxan paraxanthin.

Mlọ ọgwụ

Usoro nke ime ihe. Ihe nje bacteria na-akpata nke ciprofloxacin bụ n'ihi ihe mgbochi nke enzymes topoisomerase II (DNA gyrase) na topoisomerase IV, nke dị mkpa maka ịtụgharị, imegharị ihe, idozi ya, na ntugharị nke DNA nje.

Usoro nke mmepe nke nguzogide. Ntughari Fluoroquinolone nwere njikọ chiri anya na nsụkọta mkpụrụ ndụ ihe omimi nke DNA, na - emebi ihe mebiri emebi nke mkpụrụ ndụ, ma ọ bụ ịgbado protein protein, nke na - eduga na iwepu fluoroquinolones na sel. Na ọnọdụ in vitro Nlekọta nke ciprofloxacin na-amalite nwayọ nwayọ site na mmụkọ mgbasa ozi. Ihe kpatara iguzogide ciprofloxacin n'ihi mmụba na-esikarị ike na-adị iche na