Tsifran OD (Сifran OD)

Mlọ ọgwụ Ciprofloxacin na-arụ ọrụ in vitro ụdị gram dịtụ mma na-adịghị mma na gram-gm. Ihe nje nke aru nke ciprofloxacin bụ nsonaazụ mgbochi nke enzymes topoisomerase II (DNA gyrase) na topoisomerase IV, nke dị mkpa maka ịtụgharị, ntụgharị, ndozi, na ijeri DNA nje. Usoro nke fluoroquinolones, gụnyere ciprofloxacin, dị iche na usoro nke penisiliniins, cephalosporins, aminoglycosides, macrolides na tetracyclines. Yabụ, microorganisms na-eguzogide klaasị ọgwụ ndị a nwere ike ịdabere na ciprofloxacin na quinolones ndị ọzọ. Enweghị njikwa mgbochi n'etiti ciprofloxacin na klas ndị ọzọ nke ọgwụ nje. Nguzogide in vitro ka ciprofloxacin bidoro nwayọ. Ciprofloxacin na-arụ ọrụ megide ọtụtụ ụdị microorganisms ndị a in vitrona-efe efe na-efe efe,
aerobic gram-nti microorganisms: Enterococcus faecalis (ọtụtụ nje na-enwe ntakịrị mmetụta), staphylococcus aureus (MSSA), staphylococcus epidermidis (MSSA), staphylococcus saprophyticus, pọọgiaptoptoccus (PSSP), Streptococcus pyogenes,
aerobic gram-ọjọọ microorganisms: Campylobacter jejuni, Citrobacter diversus, Citrobacter freundii, Enterobacter cloacae, Escherichia coli, Haemophilus influenzae, Haemophilus parainfluenzae, Klebsiella pneumoniae, Moraxella catarrhalis, Straissergioerioerius geriomerierioioioioiolari , Serratia marcescens, Shigella sonnei, Shigella boydii, Shigella dysenteriae, Shigella flexneri.
Ciprofloxacin na-arụ ọrụ in vitro na site na itinye ihe nnọchi anya onye ikwu Bacillus anthracis. Ciprofloxacin nwere in vitro ntakịrị ihe mgbochi (MIC) ≤1 90g / ml n'ihe metụtara ọtụtụ (90%) nke microorganisms ndị a:
aerobic gram-nti microorganisms: Staphylococcus haemolyticus, staphylococcus hominis, ume na oyibo (PRSP),
aerobic gram-ọjọọ microorganisms: Acinetobacter iwoffi, Pasteurella multocida, Aeromonas hydrophila, Salmonella enteritidis, Edwardsiella tarda, Vibrio Cholerae, Enterobacter aerogenes, Vibrio parahaemolyticus, Klebsiella oxytoca, Vibrio vulnificus, Legionella pneumophila.
Ọtụtụ nsogbu Burkholderia cepacia na ụfọdụ eriri Stenotrophomonas maltophilia na-eguzogide ọgwụ na ciprofloxacin, dị ka ọtụtụ nje anaerobic, gụnyere Bacteroides fragilis na Clostridium mgbasa.
Mlọ ọgwụ Edebere mbadamba mkpụrụ osisi ciprofloxacin echekwabara ka ịhapụ ọgwụ nkwụ nwayọ karịa mbadamba ịhapụ ngwa ngwa. Mkpokọ ciprofloxacin na-akwadoghị na mbadamba ihe ọ bụla na mbadamba ọgwụ ciprofloxacin anaghị agbanwe agbanwe. Ihe omuma nke pharmacokinetic nke teresfloxacin nwere mbadamba ikike nke 500 na 1000 mgbe ewere otu ugboro kwa ubochi yiri nke 250 na mbadamba 500 mg na ozugbo eweputara ya ugboro abuo na ubochi AUC dika oge iri-na-ano.
Olu nke ikesa maka ciprofloxacin iv bu ihe dị 2.1-2.7 l / n'arọ. Nsonaazụ nke ọmụmụ emere site na iji ọnụ na / ojiji nke ciprofloxacin, na-egosi na, dabere na usoro eji, ọgwụ ahụ abanye na anụ ahụ dị iche iche. Njikọ nke ciprofloxacin na protein protein bụ 20-40%. Edekọtara metabolites anọpụtara na mmamịrị. Ndị metabolites ndị a nwere ọrụ antimicrobial akpọtụrụ aha karịa ciprofloxacin na-agbanweghị. Mwepu nke metabolites ndị a na-aputa ihe fọrọ nke nta ka ọ bụrụ n'ime awa iri abụọ na anọ ka etinyere ọgwụ. Ihe anaetigide tuetfloxacin na-ejigide ya ka nke na-apụtakwa mbido ciprofloxacin mbadamba. Ihe dị ka 35% nke ọgwụ onunu a na - agbanweghi na mmamịrị. Rechụpụ ugboro ugboro n'ime awa iri abụọ na anọ gachara ọgwụ a .ụchara ya. Ihe dị ka 20-35% nke ọgwụ onunu a na-eme ka ọsịpụ na - apụ apụ apụ n'ime ubochi ise. N'ime ndị ọrịa nwere obere ọrụ mkpolata, ọkara nke ciprofloxacin agbatịwo ogologo oge.

Mpempe usoro onunu ogwu

mbadamba ihe eji eme ihe nkiri.

mbadamba ụrọ ọ bụla anakwere edere nwere: Cyfran OD 500 mg
Ihe na - arụ ọrụ: ciprofloxacin - 500 mg. Tsifran OD 1000 mg
Ihe na - arụ ọrụ: ciprofloxacin - 1000 mg.
Ndị pụrụ iche: sodium alginate (Keltone LVCR), hypromellose, sodium bicarbonate, crospovidone (CLM), magnesium stearate, silloidal silicon dioxide (200), talc.

N'ọbọ ihe nkiri:
Opadry ọcha 31B58910, talcum ntụ ntụ, hypromellose, mmiri dị ọcha, ink ojii maka ihe odide ahụ (Opakod -S-1-17823 ojii).
ihe mejupụtara nke opadra ọcha 31B58910: hypromellose, lactose, titanium dioxide, macrogol 400, na-apụ n'oge mmepụta,
ihe mejupụtara gụnyere: shellac 45% (20% agbasawo) na ethanol, isopropanol, n-butanol, propylene glycol, amonia aque 28%, agba ojii.

Mpempe mwepụta

Mbadamba ọrụ ndị dị ogologo oge, 500 mg-fim kpuchie, 1000 mg. Mpempe akwụkwọ 5 kwa mbadamba ọnya, nke mebere aluminom foil dị n'otu akụkụ na aluminom foil nke nwere ihe nkiri polyamide na ihe nkiri PVC n'aka nke ọzọ, blisters 1 ma ọ bụ abụọ na igbe kaadi nwere ntuziaka maka ojiji.

Mbadamba "Tsifran OD 500 mg"
Mbadamba ụrọ ndị dị okirikiri, site na ọcha ruo ihe fọrọ nke nta ka ọ bụrụ nke na-acha ọcha, nke a kpụrụ akpụ na fim
n’akụkụ nri akwụkwọ mpịakọta e biri ebi “Cifran OD 500MG”.

Ofdị mbadamba na oge ezumike:
enwe site na-acha ọcha na-acha ọcha.

Mbadamba "Tsifran OD 1000 mg"
Mbadamba udiri ndị dị okirikiri, site na ọcha ruo ihe fọrọ nke nta ka ọ bụrụ nke na-acha ọcha, nke a na-eji fim, "Cifran OD 1000MG", edere ya nri n'otu akụkụ nke mbadamba nkume ahụ.
Ofdị mbadamba na oge ezumike: a na-agagharị site na ọcha ruo ihe fọrọ nke nta ka ọ bụrụ ọcha.

International Nonproprietary Aha

Aha ahia maka ogwu a bu Cifran®. Mba nonproprietary aha ya bu Ciprofloxacin (Ciprofloxacin). Na Latin - Ciprofloxacinum.

Ciphran na-arụ ọrụ megide ọtụtụ nje nje na nje nke microorganisms pathogenic.

J01MA02 Ọgwụ ọgwụ mgbochi nje.

Omume ọgwụ

Ciphran na-arụ ọrụ megide ọtụtụ nje nje na nje nke microorganisms pathogenic na-eguzogide aminoglycosides. Ya mere, ndị ọkachamara ahụike na-atụ aro ọgwụ a ka ọ buso ọrịa ndị agwakọtara nke anaerobic, nje aerobic na ọrịa eriri afọ. Mmetụta nje na-akpata ciprofloxacin bụ n'ihi ikike nke igbochi njikọ nke enzymes dị mkpa maka ndụ microorganism.

Ndị ọrụ ahụike na-atụ aro ka Cifran lụ ọgụ ọgụ ọgụ.

Mlọ ọgwụ

Akụkụ akụkụ nke obere eriri afọ na -akpata ya ngwa ngwa. Oke ọgwụ ịba n’ahụ na-erute mgbe awa 1-1.5 gachara. N'okwu a, iji nri anaghị emetụta ọnụọgụ mmịpụta.

Biotransformed na imeju. Ọ na - amalite iwepụ anụ ahụ site na mgbe awa 3-5 gachara, ya bụ mmamịrị ma akụkụ ya ụfọdụ n'ime eriri afọ ya. N'ime ndị nwere ọrịa akụrụ, ọkara ikpochapu ọgwụ ahụ na-ewe ogologo oge.

Ihe na-enyere aka

Edere ya ya maka ọrịa na-adịghị agbanwe agbanwe na nke mgbagwoju anya nke ọrịa na-ebute.

• sistem
• Akụkụ ENT
• anya
• mẹ onyẹ alị
• akụrụ na urogenital,
• eriri afọ
• sistem mọzụlụ.

Maka umuaka, ọgwụ a ka edepụtara maka ọgwụgwọ nke mmebi metụtara ọria akwara.

Ihe ngbanwe

Edebeghi dijitalụ ma ọ bụrụ na onye ọrịa nwere:

• uche iji ọgwụ si quinolone otu,
• ọnya na-efe efe,
• ụdị ọ bụla nke Akwụkwụ na-adọ.

A naghị atụ aro iji Digital eme ihe n'oge afọ ime na n'oge lactation.

Na mgbakwunye, dịka ntuziaka maka ojiji a na-akwadoghị ka eji rụọ ọrụ a n'oge afọ ime na n'oge ịra ahụ.

Edere ụmụaka na ndị ntorobịa naanị ịlụ ọgụ banyere ọrịa na-esite na cystic fibrosis ma ọ bụ egwu nke ọrịa anthrax.

Ejighi Ciphran jikọta ya na tizanidine.

Jiri nlezianya

N'iji nlezianya mee, ndị dọkịta dị afọ ole ka enyere, yana:

• yana ụbụrụ arteriosclerosis na ụba intracranial,
• na ọrịa obi
• ya na electrolytic ọdịda,
• ya na akụrụngwa na / ma ọ bụ ọrịa ịba ọcha n'anya,
• na ọrịa uche na Akwụkwụ na-adọ.

A na-ewere Digital 500 tupu nri, na-enweghị ị cheụ mmiri na ị drinkingụ mmiri.

O nwere oke ma ọ bụrụ na a chọpụta na mmadụ nwere ọrịa nke akụrụngwa na-ewe iwe site na ị fluụ fluoroquinolones.

Uzo esi ewere Tsifran 500

Buru tupu i rie nri, n’ebughi mmiri.

Ndị okenye maka ọgwụgwọ nke ọrịa:

• n'ụdị ọkụ na ọkara - 0.25-0.5 g ugboro abụọ n'ụbọchị.
• n'ụdị siri ike ma ọ bụ gbagwojuru anya - 0.75 g ugboro abụọ n'ụbọchị.

Ogologo oge ọgwụgwọ a na-ekpebi n'ụdị ya na ogo nke usoro ọnya ahụ na-efe efe. Ndị dọkịta na-ahụ maka inye ọgwụgwọ usoro iche iche.

Oke otu ọgwụ ahụ bụ 0.75 g, kwa ụbọchị - anaghị erughị 1.5 g.

Na ọrịa nke imeju ma ọ bụ akụrụ, usoro ọgwụgwọ kachasị kwa ụbọchị ekwesịghị gafere 0.8 g (0.2-0.4 g kwa awa 12 ọ bụla).

Ọ bụrụ na onye ọrịa ahụ na-arịa ọrịa shuga, ndị dọkịta ga-edepụta ya ka ndị dọkịta gwọọ ya.

Na-arịa ọrịa shuga

Ekwenyere na Ciprofloxacin ga-eme ka mmụba ọgwụ hypoglycemic dị elu. Ya mere, mgbe ejikọtara ihe a, dịka ọmụmaatụ, yana glibenclamide ma ọ bụ glimepiride, ọrịa hypoglycemic syndrome nwere ike ịmalite.

Ọ bụrụ na onye ọrịa ahụ na-arịa ọrịa shuga, ndị dọkịta ga-edepụta ya ka ndị dọkịta gwọọ ya.

Si na akuko obi

Sensation nke palpitations, arrhythmia, tachycardia, mgbanwe nke ọbara mgbali.

Tsifran nwere ike ibute nsonaazụ n'ụdị palpitations obi, arrhythmias, tachycardia, mgbanwe nke ọbara mgbali.

Sistemụ akwara Central

Patientsfọdụ ndị ọrịa na-egosi ihe mgbaàmà nke asthenia, nsogbu ịrahụ ụra, nchekasị, ịnụ ntị, uto oke anwụ, wdg.

Patientsfọdụ ndị ọrịa nwere nsogbu ịrahụ ụra.

Ọkpụkpụ Angioneurotic, akpụkpọ ahụ, itching na mmeghachi omume anaphylactic (adịkarịghị).

Ntụziaka pụrụ iche

Ndị ọrịa nwere akụkọ banyere ahụike nwere ozi banyere Akwụkwụ na-adọ, nkwarụ, ọrịa vaskụla ma ọ bụ ọnya ụbụrụ sitere n'ihe ize ndụ nke nzaghachi ezughị ezu site na sistemụ akwara ozi. N'ọnọdụ ụfọdụ, ọnọdụ nke psychosis na-eme, yana ịgbalị igbu onwe ya. Ya mere, a na-enye ọgwụ a naanị maka ndị gosipụtara ihe dị mkpa.

Mgbe ị na-eji ọgwụ a, ekwesịrị ịhapụ ikpughe ọkụ ọkụ, ebe ọ na-enye aka na ngosipụta nke njikwa.

Jiri na agadi

Maka ndị ọrịa nwere nsogbu ọria, ọ na-agwọ glucocorticosteroids mbụ, enwere ihe ọghọm imebi akwara Achilles. Ya mere, mgbe ihe mgbaàmà nke tendonitis pụtara, a ga-akagbu nchịkwa Cyfran.

Maka ndị ọrịa agadi nwere nsogbu, enwere ihe ọghọm nke iwepu akwara na Achilles.

Dodoụbiga ya ókè

Mgbaàmà: ọdịdị nke akpịrị, isi ọwụwa, mmetụta nke adịghị ike, ọgbụgbọ, na ọgbụgbọ. N'ihe banyere ịdoụbiga mmanya ókè, ọ dị mkpa ka a na-eme usoro iji kwụsị ị :ụbiga mmanya ókè:

• gastric lavage,
• nhọpụta nke mmetụta
• oriri nke calcium na magnesium.
• ihe eji eme ka mmiri buru ibu.

Na mgbakwunye, achọrọ iji nyochaa arụmọrụ nke usoro urinary, ebe ọ bụ na iji ọgwụ a na-achịkwaghị achịkwa, enwere mmetụta nsị na akụrụ.

Mmekọrịta na ọgwụ ndị ọzọ

Site na nhazi nke oge a nke ọgwụ obi, ọgwụ na-emegide onwe na ọgwụ na-egbochi ọgwụ, a na-ede ya nke ọma.

Na ntinye ya na Theophylline, ọ na - eme ka mmetụta ya dịkwuo elu ma na - enyere aka igbu oge n'ime ahụ.

Site n'iji phenytoin mee ihe n'otu oge, a na-ahụta mgbanwe ọnụnọ ya n'ime ọbara. Ewepu ọnọdụ nke ọnọdụ nkwenye, ọ dị mkpa ijikwa ọgwụgwọ phenytoin n'oge niile nke njikọta nkwonkwo.

NSAIDs (ndị ọzọ abụghị acetylsalicylic acid) yana otutu nke quinolones nwere ike ịkpata ọdịdọ.

Cyclosporin na Cyfran na - enyere aka ịbawanye creatinine n'ime ahụ.

Probenecid na-egbu oge ntọhapụ nke ciprofloxacin na mmamịrị.

Na methotrexate, ọ na-agbadata ụgbọ njem ọdụdụ ya na-abawanye ma na-eme ka ịta ahụhụ dịkwuo mma.

Ojiji nke Cyfran nwere vitamin K antagonists na-akwalite ihe anticoagulant ha.

Na mgbakwunye na ropinirole ma ọ bụ lidocaine, ihe ize ndụ nke ịmalite inwe mmetụta na-abawanye.

Na agha wararin, o na-abawanye nsogbu obara.

Ihe atumatu nhazi nke Cifran maka ihe eji eme ihe bu Ciprolet.

Ihe analogues nke ihe eji eme ihe bu:

• Alcipro
• Tsiprolet,
• Ciprolone
• Tsiprobay,
• Sirop
• Tsiprosan
• Tsiprosin
• Cyprosol,
• Ciprofloxabol,
• Ciprofloxacin,
• Citral
• Tsifloksinal,
• Tsifran OD,
• Tsifran ST,
• Ecocifol na ndị ọzọ.

Ogologo oge ọgwụgwọ a na-ekpebi n'ụdị ya na ogo nke usoro ọnya ahụ na-efe efe.

Nyocha ndị dọkịta na ndị ọrịa banyere Tsifran 500

Berezkin A.V., therapist, Mezhdurechensk

Ọgwụ nje nke sara mbara eji eme ihe n’ịwa ahụ, n’ịka ezin’anya, ọrịa ara, urology na ihe ndị ọzọ. Mụ onwe m depụtara ọgwụ a adịkarịghị, naanị ma ọ bụrụ na enwere ihe akaebe ma ọ bụ dịka prophylaxis mgbe arụchara arụ na mmerụ ahụ gasịrị. Echere m na ọ dị mma ma dịkwa mma iji.

Kornienko L.F., ọkachamara n'ọrịa ụmụ nwanyị, Irkutsk

Ọgwụ dị mma maka outpatient ọgwụgwọ nke mkpali ọrịa gynecological ọrịa. Otu ihe dị iche iche na-eme na-ekpebi ịdị irè nke ọgwụgwọ.

Alla, 25 afọ, Ufa

Ọrịa akpịrị metụtara ya, dọkịta ahụ kwukwara ka ọ bụrụ mbadamba 500 nke mkpụrụ osisi Cyfran otu ugboro n'ụbọchị. N'ime ụlọ ahịa ọgwụ kacha nso na usoro ịchọrọ ọgwụ a abụghị. Azụtara m na usoro nke 250 mg ma were ọgwụ 2 n'otu oge. Angina gafere n’ime ụbọchị 3, mana ọ kwụsịghị ụzọ ahụ. Were ụbọchị 10. Mmetụta ndị ọzọ na-atụ ụjọ: mmalite nke tachycardia na dysbiosis bụ ngwakọta na-adịghị mma. Ugbu a, m na-elegharị anya na a ga-agwọ ọrịa, o yighịkwa m ka m were ya na nkwanye dọkịta.

Ihe ngosiputa maka iji ogwu Tsifran OD

Ọrịa nje na-enweghị mgbagha na mgbagwoju anya nke ọrịa pathologies na-emetụta ciprofloxacin:

• ọrịa okuku ume na akwara na-efe efe: oyi ịba ọcha n'anya kpatara Klebsiella spp., Enterobacter spp., Proteus spp., Escherichia coli, Pseudomonas aeruginosa, Haemophilus spp., Moraxella catarrhalis, Legionella na staphylococci,
• ofufe ọrịa nke etiti ntị na paranasal sinuses,
• nje na-adị n’apata afọ, nje na-efe efe nke digestive tract, eriri afọ na ọnya biliary, yana peritonitis,
• akụrụ na urinary tract na-efe efe
• ọrịa nje na-efe efe (gonorrhea, adnexitis, prostatitis),
• ọrịa akpụkpọ ahụ na anụ ahụ dị nro,
• oria nke okpukpu na nkwonkwo.

Ojiji nke ogwu Tsifran OD

A na-ewere ọgwụ ahụ mgbe nri gasịrị. Erere mbadamba ihe nile. Ebipula, etipia udiri, ma obu taa. A na-ahọrọ usoro maka onye ọrịa ọ bụla na-eburu ibu ahụ, ụdị pathogen, mmetụta nke pathogen, steeti usoro ahụike nke onye ọrịa, yana akụrụ na ọrụ imeju. Oge ọgwụgwọ ọ dabere na ogo ọrịa ahụ yana ọ na - abụkarị ụbọchị 7-14.Agbanyeghị, maka ọrịa siri ike ma ọ bụ gbagwojuru anya, enwere ike ịchọ ọgwụgwọ ogologo oge.

Ọ bụ iv ciprofloxacin ya na ọnụego ya

500 mg (1 mbadamba) Cyfran OD 1 oge kwa ụbọchị

200 mg kwa elekere 12 ọ bụla

1000 mg (1 mbadamba) Cyfran OD 1 oge kwa ụbọchị

400 mg kwa elekere 12 ọ bụla

N'ime ndị ọrịa nwere nsogbu gbasara akụrụngwa arụ, ọkachasị na nnukwu akwara siri ike, achọrọ ka idozi ya.
Tebụl dị n'okpuru nwere ndụmọdụ usoro usoro eji eme ihe maka ndị ọrịa nwere ọrụ ezumike na-arụ ọrụ.

Mwepu nke creatinine, ml / min

Oge Atụrụ Arụrụ Ahụ

Mbadamba Tsifran OD 500-1000 mg 1 oge kwa ụbọchị

Agaghị atụle mbadamba nkume nke Cifran OD; mbadamba ciprofloxacin a pụrụ iji ya na ọgwụ ndị a: 250-55 mg nke ciprofloxacin kwa awa 18 ọ bụla.

Ọrịa gbasara akwara ọbara

Mpekere Cifran OD na-akwadoghị, enwere ike iji mbadamba ụrọ a na-esote: 250-500 mg nke ciprofloxacin kwa awa 24 (mgbe ọ gachara).

* N'ime ndị ọrịa nwere nhichapụ ml30 ml / min maka ọrịa urinary na-akpata mgbagwoju anya na nnukwu pyelonephritis na-enweghị mgbagwoju anya, dose ahụ bụ 500 mg nke Cyfran OD otu ugboro n'ụbọchị.

Y’oburu na itinye uche nke creatinine n’ime ọbara obara mara, enwere ike iji usoro a tughari ikuwaputa creatinine:

nke ụmụ nwoke:


nwepu okike (ml / min) =

Isi (kilogram) × (140 - afọ)

72 (plasma creatinine (mg / dl))

Enweghị mkpa ịhazigharị ọnụọgụ nke ciprofloxacin maka ndị ọrịa nwere usoro kwụ ọtọ nke ọrịa imeju na-adịghị ala ala. Agbanyeghị, ọgwụ pharmacokinetics nke ciprofloxacin na ndị ọrịa nwere oke imeju akatabeghị nyocha.

Nsonaazụ nke ọgwụ Tsifran OD

Ugboro ugboro ≥1, ≤10%
Ahụ gastrointestinal: ọgbụgbọ, afọ ọsịsa.
Akpụ: akpukpo aru.
Ugboro ugboro ≥0.1, ≤≤1%
Anụ ahụ dum: mgbu afọ, candidiasis, asthenia.
Ahụ gastrointestinal: mmụba na transpeases hepatic: AlAT, AsAT, alkaline phosphatase, vomiting, dyspepsia, anorexia, flatulence, bilirubinemia.
Usoro nke Hematopoietic: eosinophilia, leukopenia.
Usoro ure: ụba creatinine, urea nitrogen.
Usoro akwara: arthralgia.
CNS: dizzness, isi ọwụwa, ọgba aghara ụra, oke iwe, ọgba aghara.
Akpụ: itching, akpụkpọ ahụ ọkụ ọkụ nke ọdịdị ọdịdị maculopapular, urticaria.
Akụkụ akụrụngwa: uto mebiri.
Ugboro ugboro ≥0.01, ≤≤0.1%
Anụ ahụ dum: mgbu, mgbu na aka, ihe mgbu na azụ, na obi.
Usoro obi: tachycardia, migraine, syncope, vasodilation, hypotension.
Ahụ gastrointestinal: candidiasis (onu), jaundice, cholestatic jaundice, pseudomembranous colitis.
Ọbara ọbara na sistem lymphatic: anaemia, leukopenia (granulocytopenia), leukocytosis, mgbanwe na ọkwa nke prothrombin, thrombocytopenia, thrombocythemia (thrombocytosis).
Hypersensitivity: mmeghachi omume nfụkasị ahụ, ahụ ọkụ ọgwụ, mmeghachi omume anaphylactic.
Ọrịa metabolism: edema (akụkụ, vaskụla, ihu), hyperglycemia.
Usoro akwara: myalgia, ọzịza nke nkwonkwo.
CNS: migraine, hallucinations, sweating, paresthesia (peripheral paralgesia), ụjọ (ụjọ, ụjọ), nsogbu ịrahụ ụra (ụra abalị), nkwarụ, hypersthesia, ịda mba, ụjọ.
Usoro okuku ume: dyspnea, edema nke edere.
Akpụ: mmeghachi omume nsị.
Akụkụ akụrụngwa: tinnitus, ntị chiri nwa oge (ọkachasị ụda dị elu), imerụ anya (nhụjuanya anya), diplopia, chromatopsia, enweghị ụtọ (enweghi mmetụta).
Usoro ịtụgharị uche: ARF, ọrụ akụrụ na-arụ ọrụ nke ọma, candidiasis nwanyị, hematuria, crystalluria, intephitial nephritis.
Ugboro ugboro ≤0.01%
Usoro obi: vasculitis.
Ahụ gastrointestinal: candidiasis, imeju necrosis (adịkarịghị - na-aga n'ihu na mmepe nke imeju na-eyi ndụ egwu), pseudomembranous colitis nwere nsonaazụ na-egbu egbu, pancreatitis, ịba ọcha n'anya.
Ọbara ọbara na sistem lymphatic: hemolytic anaemia, petechiae, agranulocytosis, pancytopenia (nke nwere ndụ n'ihe egwu), igbochi ọrụ ụmị ọkpụkpụ (na-eyi ndụ egwu).
Hypersensitivity: ujo (anaphylactic, nke na - egbu ndu), ihe aru nke aru, mmeghachi omume yiri oria ọbara.
Ọrịa metabolism: ụba amylase na / ma ọ bụ lipase ọbara.
Usoro akwara: myasthenia gravis, akwara isi (ọkachasị akwara Achilles), akụkụ ahụ ma ọ bụ ngụgụ nke akaị (ọkachasị akwara Achilles).
CNS: ọnya siri ike nke akwara buru ibu, enweghị nsogbu, psychosis, ọbara mgbali intracranial, ataxia, hypersthesia, tic.
Akpụ: petechiae, erythema multiforme, erythema nodosum, Stevens-Johnson syndrome, epidermal necrolysis (ọrịa Lyell), ọnya na-adịgide adịgide.
Akụkụ akụrụngwa: parosmia, ọnwụ na-esi ísì ụtọ (ọ na-adịkarị ala mgbe a kagbuo ọgwụ ahụ).

Mmekorita Ogwu Cifran OD

Inwe ojiji nkezanzanine na nke a na-akpọ ciprofloxacin. Dị ka ndị ọzọ quinolones, ojiji nke ciprofloxacin na theophylline nwere ike ime ka mmụba na theophylline ịta na ọbara ọbara na ogologo nke ọkara ndụ. Nke a nwere ike ịbawanye ihe egwu mmeghachi omume metụtara theophylline. Ọ bụrụ na enweghị ọgwụ ndị a na-eme n'otu oge, agaghị egbochi ya, a ga-enyocha ọkwa ọgwụ ahụ na usoro usoro usoro onunu ogwu ahụ.
Qufọdụ quinolones, gụnyere ciprofloxacin, na-emetụta metabolism metabolism. Nke a nwere ike ibute mbelata nke caffeine na ịgbatịkwu ọkara ndụ ya site na ọbara.
N’otu oge, iji ọgwụ ọ bụla nke klaasị quinolone, gụnyere ciprofloxacin, nwere ọgwụ ọgwụ ccaic nke ọtụtụ, dịka antacids nke nwere magnesium ma ọ bụ aluminom hydroxide, sucralfate, mbadamba didanosine, ma ọ bụ ngwaahịa nwere calcium, iron ma ọ bụ zinc, nwere ike belata nnweta ya, n'ihi iweta ntinye uche na ọbara na mmamịrị ga-agbada dị mkpa.
Antagonists nke ọgwụ nnabata H2, o doro anya, anaghị emetụta oke bioav adị nke ciprofloxacin. Mwepu nke mbadamba nkume Cyfran OD nwere ike ibelata ntakịrị (20%) ma ọ bụrụ na ejiri ha na omeprazole.
A hụrụ mgbanwe mgbanwe serum phenytoin (mmụba ma ọ bụ ibelata) na ndị ọrịa na-ewere ciprofloxacin n'otu oge.
Ihe jikọtara ciprofloxacin na sulfonylurea adịkarịghị ebute nnukwu hypoglycemia.
Ceptionmata ụfọdụ quinolones, gụnyere ciprofloxacin, jikọtara ya na mmụba dị mkpirikpi na serin creatinine na ndị ọrịa na-ewere cyclosporine n'otu oge.
Enweela mkpesa na quinolones, gụnyere ciprofloxacin, na-akwalite arụmọrụ nke anticoagulant warfarin nke ọnụ ma ọ bụ nke ya. Ọ bụrụ na ọ dị mkpa, n'otu oge eji ọgwụ ọgwụ ndị a kwesịrị iji nlezianya nyochaa prothrombin oge yana ihe ndị ọzọ na-egosi coagulation ọbara. Probenecid na-emetụta ihe nzuzo nke ciprofloxacin site na akụrụ gbasara akwara, n'ihi nsonaazụ nke ciprofloxacin na ọbara ọbara na-abawanye. A ga-atụle ọnọdụ ndị a ma ọ bụrụ na onye ọrịa ahụ na-a drugsụ ọgwụ abụọ n'otu oge.
Enwere ike gbochie nnyefe Methotrexate site na obere akwara site na iji otu oge nke ciprofloxacin, nwere ike ibute mmụba na ọkwa plasma methotrexate. Nke a nwere ike ịbawanye n'ihe ize ndụ nke mmeghachi omume nsị n'ihi methotrexate. Ndị ọrịa na-anata ọgwụgwọ methotrexate chọrọ nyocha nke ọma ma ọ bụrụ na enyere ha ọgwụgwọ nke ciprofloxacin n'otu oge.
Metoclopramide na-agbadata mkpesa nke ciprofloxacin nke ọnụ na-ekwu okwu, si otú a na-abawanye oge iji ruo n'ọbara kachasị na plasma ọbara. Agbanyeghị, enweghị mmetụta ọ bụla na bioav adị nke ciprofloxacin hụrụ.

Otu ndị ọrịa pụrụ iche

Na arụ ọrụ ezumike arụrụ ọrụ: N’ebe ndị ọrịa nwetụrụ nsogbu arụ ọrụ, ọkara ndụ nke ciprofloxacin nwere ike ịbawanye ntakịrị. N'okwu a, mgbazi nke usoro usoro usoro onunu ogwu dị mkpa.

N'ihe banyere ọrụ imeju na-arụ ọrụ: Na ọmụmụ ihe mbido na ndị ọrịa nwere usoro imeju nke imeju, enweghị mgbanwe dị ukwuu na pharmacokinetics nke ciprofloxacin. Agbanyeghị, nnyocha emere gbasara kinprotiloxacin na ndị ọrịa nwere nnukwu ọrịa imeju emebeghị.

Jiri n’oge ime na n’oge a na-enye nwa ara

A naghị atụ aro Cifran OD maka iji n'oge afọ ime.
Ciprofloxacin dị na mmiri ara ara, yabụ n'oge a na-enye nwa ara, ọ bụrụ na ịchọrọ iji Cifran OD, mgbe ahụ, dabere na mkpa ọ dị maka nne, ị kwesịrị ikpebi ma ị kwụsị ị theụ ọgwụ ma ọ bụ na-enye nwa ara.

Usoro onunu ogwu na nhazi

N'ime.
Emebila, rie, ma ọ bụ bibie mbadamba ihe ndị ọzọ. E kwesịrị iji mbadamba mbadamba ndị ahụ ma ha riechaa mmiri niile.
Ojiji nke Tsifran OD kwesịrị ịga n'ihu ọ dịkarịa ala ụbọchị 2 ọzọ mgbe mwepu kpamkpam nke mgbaàmà nke ọrịa ahụ.
Gwara udiri ogwu maka ndị okenye:

Edozi usoro usoro usoro onunu ogwu ya na okuku akwara:
Ọ bụrụ na arụ ọrụ ezughi oke ọrụ, a na-atụ aro usoro usoro usoro ọgwụgwọ maka ndị okenye:

Ọ bụrụ naanị na a maara itinye plasma creatinine, a na-akwado usoro a maka
nkọwapụta nkọwapụta nke creatinine:
Ndị ikom:

Mkpokọta creatinine (ml / min.) = Ikike anụ ahụ (kg) x (140 - afọ) / 72 x serin creatinine (mg%)
Mụ nwanyị:
Mkpokọta nke creatinine (ml / min.) = Akara ngosi 0.85 x maka ụmụ nwoke.

Mmetụta akụkụ

Site na nri digestive: ọgbụgbọ, ọgbụgbọ, afọ ọsịsa, ọnya afọ, flatulence, anorexia, cholestatic jaundice (ọkachasị ndị ọrịa nwere ọrịa imeju gara aga), ịba ọcha n'anya, ịba ọcha n'anya.

Si ụjọ usoro: dizziness, photophobia, insomnia, paresthesia, irritability, isi ọwụwa, ike ọgwụgwụ, ụjọ, ụjọ, nrọ "nro abalị", nhụjuanya isi ike (anomaly in per Iroranial pain), ịba ụba intracranial pressure, ọgba aghara, nkụda mmụọ, hallucinations, yana ngosipụta ndị ọzọ. Mmeghachi omume psychotic (oge ụfọdụ na-aga n’ihu na ọnọdụ onye ọrịa nwere ike imerụ onwe ya ahụ), migraine, nkụda mmụọ, thrombosis akwara.

Si uche: ọgba aghara na ụtọ na ísì, imerụ anya (diplopia, discoloration), tinnitus, ọnwụ ịnụ.

Si usoro obi: tachycardia, arrhythmias nke obi, belatara obara mgbali obara, igbapu obara n’onu nke iru.

Site na usoro hematopoietic: eozoftft, leukopenia, granulocytopenia, anaemia, thrombocytopenia, leukocytosis, thrombocytosis, hemolytic anaemia.

Nnyocha ụlọ nyocha: hypoprothrombinemia, ụba ọrụ nke ọrịa hepatic transaminases, hypercreatininemia, hyperbilirubinemia, hyperglycemia, mụbara ọrụ nke alkaline phosphatase na dectrogenase lactate.

Site na urinary system: hematuria, crystalluria (ọkachasị na mmeghachi nke alkaline nke mmamịrị na ala diureis), nephritis na-arịa nnukwu ọrịa (na mmepe nwere ike ịda mba), glomerulonephritis, dysuria, polyuria, njigide nke urinary, albuminuria, ọbara urethral, ​​belatara ikuku ọrụ akụrụngwa akụrụ.

Mmeghachi omume nfụkasị ahụ: Ọkpụkpụ akpụkpọ, hives, etolite nke ọnya tinyere ọbara ọgbụgba, na ọdịdị nke obere nodules na-akpụ scabs, fever fever, hemorrhages na akpụkpọ ahụ (petechiae), ọnya nke ihu ma ọ bụ ogwooro, ọnyụnyụ ahụ, vasculitis, erythema nodosum, erythema multiforme exudative (malignant eryma Stevens-Johnson syndrome), necrolysis na-egbu egbu (nke ọrịa Lyell).

Site na usoro mọzụlụ: ọrịa ogbu na nkwonkwo, ọrịa ogbu na nkwonkwo, tendovaginitis, ọrịa tendon, myalgia.

Ndị ọzọ: ọsụsọ mụbara, onyonyo, adịghị ike n'ozuzu ya, superinfection (candidiasis, pseudomembranous colitis).