Insulin Vozulim n: oru nke ọgwụ ogwu

• 1 Ngwakọta na ụdị ntọhapụ
• 2 usoro ihe
• 3 Ihe ngosi maka ojiji
• 4 Ntuziaka maka iji "Manil" na-arịa ọrịa shuga
• 5 Jiri n’oge ime na lact
• 6 Jiri na nwata na agadi
• 7 Ihe mgbochi
• 8 mmetụta
• 9 dodoụbiga ya ókè
• 10 Mmekorita ya na uzo ndi ozo
• Ọnọdụ ezumike na nchekwa
• 12 Ọgwụ ọgwụ analogues
• 13 Nsogbu na Uru

Maka ọgwụgwọ nkwonkwo, ndị na-agụ akwụkwọ anyị ejirila DiabeNot nke ọma. Thehụ ihe ndị ama ama n’ahịa a, anyị kpebiri inyefe ya n’aka gị.

A na-eji mbadamba ọgwụ Maninil na-emeso ụdị ọrịa mellitus 2 nke ọrịa ma ọ bụrụ na usoro ọgwụgwọ na usoro mmega ahụ ewetabeghị mmetụta hypoglycemic. N'agbanyeghi eziokwu na ogwu ogwu bara ezigbo aru, o nwekwara otutu ọghọm ya, yabụ, tupu iji ya, ọ dị mkpa ka gị na ndị ọkachamara ahụike gị kpọtụrụ.

Ngwakọta na ụdị ntọhapụ

A na-emepụta ọgwụ hypoglycemic Maninil n'ụdị mbadamba pink. Ngwakọta dị n'ọrụ bụ glibenclamide na ọnụọgụ nke 1.75, 3.5 na 5 milligrams, dabere na usoro onunu ogwu. Ihe ndi ozo bu lactose monohydrate, stachi, magnesium stearate na silicon dioxide. Enwere mbadamba nkume n’ime karama 120 iberibe.

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Usoro nke ime ihe

N'iji ihe na-arụ ọrụ nke bụ akụkụ nke Maninil, ọ ga-ekwe omume iwelie mmetụta insulin, mee ka ntọhapụ ya dịkwuo elu, ma bulie mmetụta nke insulin na nnabata nke glucose site na umeji. Na mgbakwunye, ọgwụ ahụ na-ebelata arịa thrombogenic nke ọbara ọbara. Mbelata glucose n’anụ ahụ na-apụta awa 2 mgbe nchịkwa gachara were ihe dị ka otu ụbọchị.

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Ihe ngosi maka ojiji

Imirikiti, a na-eji ọgwụ ahụ agwọ ọrịa ụdị shuga na-akpata insulin na ịchịkwa ụkpụrụ glucose. Edekwara ya mgbe ọ ga - eme:

• ime ka aru mara ndi oria ibu
• a na-achọpụta hyperglycemia na-adịghị ala ala.

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Ntuziaka maka iji "Manil" na-arịa ọrịa shuga

A na-ewere mmiri a zuru oke.

A na-a medicationụ ọgwụ ọrịa shuga tupu nri, ebe ọ na-adịghị mkpa ka a ta ata ya na ọ ga-eji obere mmiri hichaa ya. A na - enyekarị ya otu ugboro kwa ụbọchị (n'ụtụtụ ụtụtụ). Ọ bụrụ na onye ọrịa chefuru ị theụ ọgwụ, a ga-eme nke a ozugbo o chetara ya. N'otu ụbọchị ahụ, amachibidoro ị aụ ọgwụ abụọ.

Usoro onunu ogwu a nwere metụtara otutu onye oria, ogo nke oria ya na ọkwa suga. Oge mbụ ọrịa shuga na-agụnye iji otu ma ọ bụ abụọ mbadamba otu ugboro n'ụbọchị. Ọ bụrụ na usoro ọgwụgwọ a anaghị enye ọgwụgwọ ọgwụgwọ achọrọ, enwere ike ịbawanye ike n'okpuru nlekọta ndị dọkịta. N'okwu a, ọnụọgụ ahụ na-abawanye nwayọ. O kwere omume ị drinkụ ihe karịrị mbadamba 5-6 kwa ụbọchị.

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Jiri n'oge ime na lactation

Ọgwụ maka ọrịa shuga “Maninil” 5 na ụdị ndị ọzọ ka edeghị ya n'oge ịtụrụ ime na inye nwa. Ndị ọrụ ahụike mara na ọ dị mkpa iji ọgwụ mgbochi ndị a pụrụ ịdabere na ya na usoro ọgwụgwọ iji zere ịtụrụ ime. Ọ bụrụ na afọ ime, iji ọgwụ a ga-akwụsị ya ozugbo.

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Jiri na nwata na nká

Ntuziaka maka ojiji na-elekwasị anya n'eziokwu ahụ bụ na ọgwụ "Maninil", nke a na-eji na-agwọ ọrịa shuga, amachibidoro iji ụmụaka na-erubeghị afọ 18. Ntinye akwụkwọ maka ịka nká nwere ike ịnwe, mana ekwesịrị ịme ya n'okpuru nlekọta ndị dọkịta mgbe niile. Na mgbakwunye, a ga-ebelata usoro ọgwụgwọ nke ọgwụ mbụ, ebe ọ bụ na anaghị etinye ihe ize ndụ nke hypoglycemia (mbelata mgbanye glucose na ahụ).

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Ihe ngbanwe

Ihe mgbochi intestinal bụ mgbochi megide ị .ụ ọgwụ.

Amachibidoro ịgwọta ọrịa shuga ma ọ bụrụ na achọtara onye ọrịa ahụ:

• anabataghị ihe ụfọdụ,
• ụdị shuga 1
• ketoacidosis
• Coma
• mwepu aka na-arụ ọrụ nke imeju,
• imebi akụrụ
• hemopoiesis ọrịa nke mkpụrụ ndụ ọbara ọcha,
• mgbochi afọ,
• anagide ekweghị ekwe.

Edebere onye na-ahụ maka ọgwụ na izizi ma ọ bụrụ na achọpụta ụdị mgbatị ahụ:

• oria nwa n’olu,
• ahụ ọkụ
• na-enye nsogbu nke kotesụ adrenal,
• a .ụrụma
• egbu egbu egbu
• toro ogo site na afọ 70.

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Nsonaazụ

Mgbe ụfọdụ “Maninil” na-akpata ụdị mgbaàmà ndị a:

Nausea bụ otu n'ime mmetụta ndị dị na ị ofụ ọgwụ.

1. Ọkpụkpụ afọ:
   • nsogbu nke ọgbụgbọ
   • gagging
   • mgbu n’afọ
   • uto nke metal n'ime onu.
   • glucose na-ebelata
   • I nweta ibu.
2. Akpụ:
   • itching na ọkụ
   • pemphigus
   • ịmụba uche na radieshonlet radieshon,
   • olu mgbu
   • nkwonkwo mgbu
   • jaundice
   • Udeme nke Quincke.
3. Akụkụ Hematopoietic:
   • mbelata plate
   • ọbara ọcha, dị n'ọbara.
   • ọnụ ọgụgụ nke mkpụrụ ndụ ọbara uhie,
   • mbelata nke ọnụ ọgụgụ ọbara ọcha.
4. Ohaneze:
   • isi ọwụwa
   • adịghị ike
   • obi uto
   • ogwe
   • mgbagwoju anya nke mmeghari
   • imebi moto na ikwu okwu.

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Dodoụbiga ya ókè

Anụ ọgwụ ọ ofụ ,ụ gabigara ókè, okpomoku ahụ ga-amụba.

N'ọnọdụ ịdoụbiga mmanya ókè, onye ọrịa ahụ nwere mgbaama ndị a:

• mụbara agụụ,
• ahu ọkụ
• obi rya na nkpagbu,
• obi uto
• isi ọwụwa
• imebi ihe omume na ikwu okwu.

Ọ bụrụ na achọpụtara ụdị mgbaàmà ndị a, ọ dị mkpa iri otu shuga ma ọ bụ nri nwere glucose ngwa ngwa o kwere mee. Ọ bụrụ na akpịrị na-adị, a na-a gluụ glucose n'oge.

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Mmekọrịta na ụzọ ndị ọzọ

Site na iji ọgwụ ahụ n'otu oge na anabolics, ọgwụ mgbochi anti-mbufụt, ndị na-egbochi ACE, ọgwụ hypoglycemic ndị ọzọ na beta-blockers, mmụba nke mmetụta nke ọgwụ ahụ bụ iji belata ọkwa glucose. Mbelata ịdị irè nke Maninil na-apụta na otu ngwa nwere barbiturates, glucocorticoids, diuretics nke otu thiazide, ọgwụ mgbochi na ọgwụ, nke gụnyere lithium.

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Ezumike na ọnọdụ nchekwa

Inwere ike ịzụta ọgwụ “Maninil” n’agbụ ụlọ ọgwụ naanị maka ihe dọkịta edere, nke akara a kara aka. Ntụziaka maka ojiji na-egosi na ekwesịrị idobe ngwaahịa a na nkụ, ọnọdụ okpomọkụ nke agaghị agafe ogo 30. Anụmanụ a ekwesịghị ịnwe ụmụ anụmanụ, ụmụaka na ìhè anyanwụ. Ogologo oge nchekwa ekwesighi gafe afọ 3 site na ụbọchị emepụtara, ụbọchị egosipụtara na kaadiboodu.

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Analogs nke ọgwụ ọgwụ

A na-ewere Glibenclamide dị ka analog nke ọgwụ.

Naanị ọgwụ analog, nke gụnyere otu ihe ahụ na-arụ ọrụ dị ka nke dị na Maninil, bụ ihe a na-ewere dị ka ọgwụ Glibenclamide. Ndị ọzọ na-ahụ maka ọgwụ nwere mmetụta hypoglycemic nwere ụdị ọrụ na-arụ ọrụ n'ahụ, mana ihe ọzọ na-arụ ọrụ. Ọ dị mkpa iburu n’obi na a machibidoro iwu iji dochie anya Maninil na ntụnyere nke onwe ya, ebe ọ bụ na usoro ndị a nwere ike ọ bụghị naanị inye aka n'ịgwọ ọrịa shuga mellitus, kamakwa ọ na-emebi ahụ ike gị.

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Nsogbu na Uru

Edebere “Maninil” maka ọrịa shuga n'ọgwụgwọ ya, ana-ahụta ya dị ka ọgwụ dị irè. Ọ na-enyere ọ bụghị naanị na nnukwu shuga, a na-enye ya ọgwụ maka ndị nwere ahụike ka ha chịkwaa glucose ọbara. Agbanyeghị, n'agbanyeghị ịdị irè ya na usoro ọgwụgwọ, o nwekwara ọghọm n'ụdị ọnụọgụ contraindications na mmetụta ndị zuru oke. Otu n'ime ihe kachasị njọ n'ime ha bụ ịmalite hypoglycemia, nke na-akpata nnukwu ahụ n'ahụ.

Insulin Vozulim n: oru nke ọgwụ ogwu

A na-eji nkwadebe insulin mee ihe maka iji ọgwụ dochie ndị ọrịa nwere ọrịa shuga. Edebere ha site na oge ime ha to obere na ogologo. Oge ọrụ maka ndị dị iche iche bụ nke onwe ya. Ya mere, nhọrọ nke ọgwụ insulin na-arụkarị n'ụlọ ọgwụ.

Iji mezuo nke a, na-achịkwa ọkwa nke glycemia n'ụbọchị. Mgbe ahụ dọkịta depụtara usoro ọgwụ insulin dị iche iche dabere na ọnụego metabolic, nri, mmega ahụ, ijikọta ụdị ọgwụ dị iche iche.

Ka a na-akwụghachi ụgwọ metabolism karị, ọ na -ewekarị ntakịrị ntakịrị kwa ụbọchị na glucose ọbara, ma, ya mere, belata ihe egwu nke ọrịa shuga.

Iwu dị mkpa maka ọgwụgwọ insulin

Dị ka ọ na-adịkarị, a na-emepụta 23-59 IU nke insulin, nke a bụ ihe dịka 1 n'arọ nke anụ ahụ - 0.6 - 1.0 UNITS. A na - ekewa secretion a na basal na nri (bolus). Ihe nzuzo insulin na-enwe ihe dị ka nkeji 1 kwa elekere. Nri kpaliri, imepụta na mwepụta nke insulin - 1 otu maka carbohydrates ọ bụla 10 ma ọ bụ 12 g (1XE).

Mkpa insulin dị ukwuu n'ụtụtụ, ọ na-enwekwu uche na mgbede. Nke a dị mkpa maka ịhazi usoro nchịkwa ọgwụ, ebe ebumnuche nke ọgwụ insulin bụ ime ka nhazi insulin nke usoro iche iche nke nzuzo ha.

A na-akpọ usoro a ntọala-bolus ụkpụrụ nke nchịkwa insulin. Ọ na-eme ka ọgwụ insulin gbasie ike na ojiji ndị na-ewepụta ọgwụ insulin. Kpoo nzuzo nke insulin n’usoro, belụsọ maka carbohydrates (glucose), amino acids na protein.

Insulin eweputara nwere uzo ozo di iche iche, nke ozo dabere na ihe ndi a:

Kacha mkpa n’ime ndị a:

• Okpomoku nke ikwado insulin, ike ya.
• Olu nke igba ogwu.
• Oria ogwu (ngwa ngwa site n’ahu akpukpo ukwu nke obia, dikwa nwayọ site n’apata ma obu ubu).
• Mmega ahụ.
• Ọnọdụ Sistemu na-enwe Ọrịa

Ebumnuche nke ọgwụgwọ insulin: Vozulim N, ihe ngosi

Edebere insulin iji mee ka metabolism metabolism dị ọcha. Nke dabara na, nke a pụtara inweta glucose ọbara na-ebu ọnụ, na-egbochi mmụba dị mma mgbe ị risịrị nri, ekwesighi inwe glucose na mmamịrị, enweghị mwakpo hypoglycemia.

Ndị na-egosipụta afọ ojuju izi ezi nke ọgwụgwọ ahụ bụ mbelata ma ọ bụ iwepụ isi ihe kpatara ọrịa shuga, enweghị ketoacidosis, hyperglycemia siri ike, ọgụ ugboro ugboro nke hypoglycemia.

Maka ọgwụgwọ nkwonkwo, ndị na-agụ akwụkwọ anyị ejirila DiabeNot nke ọma. Thehụ ihe ndị ama ama n’ahịa a, anyị kpebiri inyefe ya n’aka gị.

Ọgwụ insulin na-enye gị ohere idowe ahụkarị ndị ọrịa ma rie nri nwere carbohydrates (ewezuga nke ndị dị mfe), jigide mkpokọta ahịrị lipoproteins, cholesterol.

Ebumnuche kasịnụ nke ọgwụ insulin bụ ndụ nkịtị, ikike ijikwa ndị na-elekọta mmadụ. Oge nchịkwa insulin n'oge kwesịrị ekwesị na-enyere aka igbochi ma ọ bụ belata nsogbu akwara ozi na akwara.

Isi ihe na - egosi maka ideputa ọgwụ nwere insulin maka ọrịa shuga bụ:

1. Firstdị shuga mbụ.
2. Ketoacidosis (ịdị iche na ogo).
3. Coma: hyperosmolar, ketoacidotic, lactic acidosis.
4. Ọrịa nke ogo ogo na nnukwu purulent Filiks.
5. Erkwara nta
6. Ibelata mfu mberede.
7. Ọrịa na –emeghachi ugboro ugboro, ọria, pancreic necrosis.

A na - eji insulin eme ihe n'agbanyeghị ụdị ọrịa shuga n'ihu microangiopathies siri ike na ọrụ akụkụ ahụ, oke mgbasa ọbara nke ụbụrụ na myocardial infarction, ịwa ahụ.

N'ime ụdị ọrịa shuga abụọ nke ọrịa shuga, a na-egosikwa insulin maka iguzogide ọgwụ a na-aralụ a andụ na nnukwu hypertriglyceridemia, a na-eji ya mee ihe banyere ọrịa shuga na-enweghị oke.

Etu esi abanye Vulim N?

Ọgwụ bụ insulin mmadụ, isofan, nke enwetara site na inyocha mkpụrụ ndụ ihe nketa. Dodị usoro onunu ogwu bụ nkwusioru maka nlekọta n'okpuru anụahụ. Otu mililita nwere inspee 100 nke insulin. Odikwa na 10 mil vials na katrized na olu nke 3 ml.

Iji banye Vozulim N, ịkwesịrị ịma otu esi etinye insulin n'ụzọ ziri ezi. Tupu okwu mmeghe, ị ga - eburu vial ya na friji n'ime nkeji iri atọ. Lelee ụbọchị mwepụta na ụbọchị mmebi. Ọgwụ mebiri emebi ma ọ bụ meghee ọgwụ karịa ụbọchị 28 gara aga, enweghị ike ịnye ya.

Ekwesịrị ịsa ya naanị ma ọ bụ sachaa aka ya na akpụkpọ dị ọcha (ekwesịghị ịkpụ mmanya). Ekwesịrị ịgagharị karama insulinul Vozulim N aka ya ka agba nke nkwusioru ya gh o ocha, urukpuru.

Ọ bụrụ na ejiri sirinye jiri ọgwụ ntụtụ ahụ, a ga-ahụrịrị iwu ndị a:

• Ejila ihu ọ bụla dị n'elu agịga.
• Jiri nlezianya lelee dose nke insulin.
• Ebe a na-agba agba mmiri ekwesịghị ịdị nso na ntụpọ ojii n'ahụ (dị nso karịa 2.5 cm) ma ọ bụ otube, ị nweghị ike ijigide ebe ahụ mmerụ ahụ ma ọ bụ ọzịza.
• Mgbe ịgba ntụtụ ahụ, sirinji ahụ kwesịrị ịdị n'okpuru akpụkpọ ahụ maka sekọnd 5 ọzọ.
• Ekwesịrị iji kpochapụ agịga ahụ na sirinji ka ejiri ọgwụ ahụ.

Site na ntinye ọgwụ iji mkpịsị sirinji mee ihe, ịkwesịrị ịtọ onye nkesa ahụ na ọkwa ịchọrọ wee pịa bọtịnụ mmalite. Mgbe nke ahụ gasị, jide mkpịsị ahụ maka sekọnd iri n'enwepụghị ya na akpụkpọ ahụ. A ga-atụfu agịga ejiri.

A ga-agbanwerịrị ebe a na-agba agba mgbochị, na-eme atụmatụ onwe gị. Iji belata nro, ịchọrọ inwe agịga dị warara ma dị mkpụmkpụ.

Kedụ ka Vulim N si eme ihe mgbe nchịkwa gasịrị?

Vozulim N bụ insulin nke na - agbanwe ike mmadụ. Iji bido iwetulata shuga dị ala, ọ ga-ejikọ otu onye nabata ihe mejupụtara ya na akpụkpọ ahụ dị na sel. Vozulim N mepụtara insulin + receptor complex nke na-akpali mmeghachi nke biochemical intracellular.

Mbelata nke glycemia nwere njikọ na ịba ụba nke glucose site na mkpụrụ ndụ yana ntinye ya na usoro metabolic nke glycolysis maka ike. Insulin nwekwara ikike iji mee ka okpukpo oku na glycogen me ngwa. N'ime mkpụrụ ndụ akwara, mgbochi nke ụmụ irighiri glucose ọhụụ na mmebi nke ụlọ ahịa glycogen ka egbochi.

Oge ihe insulin Vozulima N mere bụ n'ihi ọnụego mmiri. Ọ dabere na ọtụtụ ihe: dose, usoro, ebe nchịkwa. N'akụkụ a, profaịlụ nke insulin na-arụ ọrụ metụtara mgbanwe n'etiti ma ndị ọrịa dị iche iche na otu onye ahụ.

Mmetụta ọgwụ ahụ na-amalite 1 awa mgbe nchịkwa, mmetụta kachasị (ọnụ ọgụgụ kachasị elu) dị n'agbata awa 2 na 7, oge ọrụ nke Vozulima N bụ awa 18-20. Emebiwo site na insulinase n'ime imeju. Ọ na-apịpụta akụrụ.

Atụmatụ eji Vozulima N:

1. Enwere ike inye ya ndi nwanyi di ime na oge inye ara.
2. A na-eme ntụtụ ahụ n'okpuru anụ ahụ, ihe ngwọta kwesịrị ịdị na nrị ahụ ụlọ.
3. Nchịkwa nwere ike ime n'otu oge insulin mkpụmkpụ - Vozulim R.
4. Jiri kateeti maka mkpịsị sirinji.
5. N'ihi na enwere ike ịdapụ mmiri, anaghị atụ aro iji ọgwụ nfuli insulin.

Ọ bụrụ na edepụtara insulin na nke izizi ma ọ bụ agbanweela, ya na nnukwu nrụgide anụ ahụ ma ọ bụ nke uche, mgbe ahụ, belata ikike ịnya ụgbọ ala ga-ekwe omume. Ijikwa usoro na-aghọ ọrụ dị ize ndụ.

Ya mere, ha anaghị akwado ọrụ chọrọ nlebara anya ka ukwuu, ọsọ nke uche na moto.

Nsonaazụ na nsonazụ

Nchịkwa nke insulin na-edugakarị na mbelata shuga ọbara. Obi ndị ọrịa nwere ọrịa shuga anaghị egosipụta ya mgbe niile gbasara ọnọdụ ụlọ ọgwụ. Na neuropathy na-arịa ọrịa mamịrị, enwere ike ghara ịchọpụta mbelata ọbara dị ukwuu, na ọrịa shuga na-agbasa, ọbụna ntakịrị ntakịrị na glycemia na-akpata ahụ erughị ala.

Mgbaàmà nke mwakpo hypoglycemic metụtara ọrụ nke usoro enweghị ọmịiko na mbelata inye nri n'ụbụrụ. Ọsụsọ, agụụ, aka na-ama jijiji, nchekasị dị n'ime, ọnụọgụ egbugbere ọnụ na ire, adịghị ike pụtara.

Ihe ngosi nke hypoglycemia na-eme n'ihi na ụbụrụ enweghị ụlọ nchekwa glucose nke ya, ma mgbe wedata nri ahụ, ọ na-emeghachi omume hypoxia na ọgbụgba, adịghị ike, na ihe oriri. Mgbe ahụ, a na-agbanye mkpịsị akwara na ọnya pituitary, a na-ahapụ homonụ. A malitere usoro nke mmeghachi omume homonụ iji weghachi ọrịa glycemia.

Iji gwọọ hypoglycemia na mbido mbụ wee ruo n’ọ̀tụ̀tụ̀ dị nro, o zuru ezu ị sugarụ shuga, mmanụ a ,ụ, swiiti, mbadamba glucose. N'ọnọdụ dị njọ na mmụọ nwere nsogbu, a ga-akpọrịrị ndị ọrịa n'ụlọ ọgwụ ebe a na-etinye glucose na-egbu egbu ma na-egbu glucagon.

Udiri hypoglycemia ugboro ugboro na ọrịa shuga mellitus na-eduga na mmepe nke insulin overdose syndrome (Somogy syndrome). Ihe omuma ya banyere ya bu ndi a.

1. Ochicho insulin (iguzogide insulin).
2. Lazọ ọrịa shuga (pseudolability).
3. Igha ibu ma ọ bụ oke ibu nwere nnukwu glycosuria.
4. Bawanye metabolism n'ihi ọrịa concomitant ma ọ bụ iwetulata dose ahụ.
5. Achọla ịdị mma nke ịba ụba.
6. Obi agụụ na-agụkarị ya.
7. Nnukwu mgbanwe dị n’ọkwa glucose dị n’ọbara na mmamịrị.

Iguzogide ọgwụ insulin nwere ike ịmalite, ọbụlagodi nkeji iri asatọ anaghị ebute nsonaazụ achọrọ, a na-ahụkwa ọgwụ mgbochi ọgwụ insulin n'ime ọbara. Nlegide insulin bu nwa oge (ya bu oria, oria, ihe ojoo nke oria ma obu endocrine) na agbatịwo.

A na-egosipụta mmeghachi omume Allergic n'ozuzu na insulin n'ụdị edere Quincke ma ọ bụ urticaria juputara, ha dị ụkọ. Ejiri mmeghachi omume mpaghara bụ ọdịdị hyperemia, ọzịza na ntụtụ ebe insulin ma ọ bụ itching akpụkpọ. Dị ka ọ dị, ngosipụta mpaghara anaghị achọ ọgwụgwọ ma na-apụ n'anya n'enweghị nsonaazụ ya.

Lipodystrophy dị na ntanetị nke inulin, yana usoro atrophic na anụ ahụ subcutaneous, mgbe a na-abanye insulin mmadụ, na-eme ihe megidere nchịkwa insulin, yana mmeghachi omume mgbochi ọrịa na ndị ọrịa maara banyere nhazi insulin. Maka mgbochi, ịkwesịrị ịgbanwe ebe ntụtụ.

Na nmalite ọgwụgwọ insulin ma ọ bụ mmụba nke usoro nchịkwa, insulin edema na-etolite, nke na-apụ n'anya na-enweghị ihe ọureụ diụ n’otu ọnwa. Ejikọtara nke a na mmepe mmeghachi omume immunological na njigide sodium n'ahụ.

Ededị edema ahụ nwere ike ịpụta na nkwarụ anya nke na-adịghị ala ala na mmalite nke iji nkwadebe insulin. Oghere ahụ na-agbanwe ike ya na ndị ọrịa na-enwe ọhụhụ na-adị nwa oge na agụ ọgụgụ. Njirimara a nwere ike inogide site na otutu izu ma ochoghi ọgwụgwọ ma obu iko nke ndozi.
Vidio dị n’isiokwu a na-egosi usoro eji edozi insulin.

Ngwá ọgwụ ọgwụ:

Mlọ ọgwụ Vozulim-N bụ nhazi oge insulin nke mmadụ na-agbakọta. Ọ na - emekọrịta otu onye na - anabata ihe n'ụsọ akpụkpọ ahụ cytoplasmic nke mkpụrụ ndụ ma mepụta insulin-receptor complex nke na - akpali usoro intracellular, gụnyere njikọ nke ọtụtụ enzymes isi (hexokinase, pyruvate kinase, glycogen synthase, wdg). A na - eme ka mbelata ọbara glucose ọbara site na mmụba na ntinye ya n'ime intracellular, ịba ụba na nnabata site na anụ ahụ, mkpali nke lipogenesis, glycogenogenesis, mbelata nke mmepụta glucose site na imeju, wdg. Oge nke ihe a na - akwadebe insulin bụ nke kachasị nke a na-ekpebi na ọnụego nnabata, nke dabere na ọtụtụ ihe (dịka ọmụmaatụ, dose , usoro na ebe nchịkwa), n'ihe metụtara profaịlụ nke insulin na-agbanwe n'ọtụtụ mgbanwe, na ndị dị iche iche na otu onye. Mmalite nke ị ofụ ọgwụ ahụ bụ 1 awa mgbe nchịkwa gasịrị, nsonaazụ kasịnụ dị n'agbata awa 2 na 8, oge ọ ga-amalite bụ awa 18-20.

Mlọ ọgwụ Izu oke nke nnabata na mmalite nke mmetụta nke insulin na-adabere n'ụzọ nke nchịkwa (subcutaneously, intramuscularly), ebe nchịkwa (afọ, apata ụkwụ, isi), dose (olu insulin insulin), itinye uche nke insulin na ọgwụ, wdg A na-ekesa ya n'ụzọ na-enweghị isi gafee akwara ma ghara ịgafe ihe mgbochi placental. na ara ara. Ọ bụ insulinase na-abụkarị imeju ya na akụrụ. Ọ bụ ya bụ akụrụ (30-80%).

Leasedị ntọhapụ, ihe mejupụtara na nkwakọ

3 ml - katọn (1) - ngwugwu na-acha uhie uhie (1) - ngwugwu nke kaadiboodu.
10 ml - karama (1) - ngwugwu na-acha uhie uhie (1) - ngwugwu nke kaadiboodu.

Ogologo oge insulin (ATX A10AC)

Tebụl analogues na ọnụ ahịa ya

Protafan NM - ntuziaka maka ojiji (adịghị adị)

Enwere contraindications. Gakwuru dibia bekee tupu iwere ya.

Insulin niile dị ebe a.

Medicationsdị ọgwụ shuga Type 2 dị ebe a.

Ọgwụ niile ejiri na endocrinology dị ebe a.

Can nwere ike jụọ ajụjụ ma ọ bụ hapụ nyocha gbasara ọgwụ (biko echefula igosi aha ọgwụ ahụ na ederede ozi) ebe a.

Oge Nkwadebe Ọkara Na-enwe Insulin Injinịa Inyocha Ọmụmụ (Human Insulin, koodu ATX (ATC) A10AC01):

Kedu ọnụọgụ kachasị dị mma?

Omume ọgwụ

Vozulim 30/70 bu mmanu insulin nke na-agaghari nke oma. Ihe mejupụtara ọgwụ ahụ gụnyere insulin soluble (30%) na insulin-isophan (70%).

Ọ na - emekọrịta otu onye na - anabata ihe n'ụsọ akpụkpọ ahụ cytoplasmic nke mkpụrụ ndụ ma mepụta ogige insulin-receptor na-akpali usoro intracellular, gụnyere

njikọ nke ọtụtụ enzymes isi (hexokinase, pyruvate kinase, glycogen synthase, wdg).

A na-eme ka mbelata ọbara glucose ọbara site na mmụba na njem nke intracellular ya, mmụba dị ukwuu na njigide anụ ahụ, mkpali nke lipogenesis, glycogenogenesis, mbelata ọnụego glucose sitere na imeju, wdg.

Ogologo oge nke ihe insulin na-eme bu n'ihi nzere nke mmiri, nke dabere na otutu ihe (dika ima atu, uzo ya na ebe ochichi ya), ya mere profaịlụ nke insulin n’ariri mgbanwe di omimi, ma n’ebe ndi mmadu di iche na otu mmadu.

Nmalite mmalite mgbe nchịkwa subcutaneous dị mgbe nkeji 30 gasịrị, nsonaazụ kachasị bụ mgbe elekere 2-8 gachara, oge ọrụ ahụ ruru awa 24.

Usoro usoro onunu ogwu

Ezubere ọgwụ a maka nchịkwa okpuru ala. Ọ bụ dọkịta ga-ekpebi ọ̀gwụdị na oge ịhazi ọgwụ ahụ n'otu n'otu n'ọnọdụ ọ bụla dabere n'ọbara glucose ọbara. Na nkezi, kwa ụbọchị ọgwụ a sitere na 0,5 ruo 1 IU / kg body body (dabere na njirimara nke onye ọrịa na ịba ụba glucose ọbara).

Okpomoku nke mmanu insulin kwesiri ino na okpomoku. A na-enyekarị ọgwụ a n'okpuru subcutaneously na apata ụkwụ. Enwere ike ịmekwa ya na mgbidi nke oghere ihu, ogwe ma ọ bụ ubu na ịkọwapụta akwara ahụ. Okwesiri igbanwe ebe ogwu ngbanyere na mpaghara anatomical iji gbochie mmepe nke lipodystrophy.

Enwere ike inye ndị ọrịa nwere ụdị ọrịa shuga abụọ nke mellitus ma ọ bụ ọgwụ ọgwụ Vozulim 30/70 (obere oge nchịkwa ugboro 2 n'ụbọchị), ma ọ bụ ọgwụgwọ ngwakọta na ndị nnọchianya hypoglycemic ọnụ. Jiri mkpịsị sirinji jiri naanị sirinji.

Mmetụta akụkụ

N'ihi mmetụta nke metabolism metabolism: Ọnọdụ hypoglycemic (pallor nke anụ ahụ, ịba ụba ọsụsọ, palpitations, ịma jijiji, agụụ, mkpasu iwe, paresthesia nke mucosa aral, isi ọwụwa). Nnukwu hypoglycemia siri ike nwere ike iduga mmepe nke hypoglycemic coma.

Mmeghachi omume nfụkasị ahụ: ọnya ọnya, ọnya Quincke, nke dị ụkọ - ujo anafilactic.

Mmeghachi omume mpaghara: hyperemia, ọzịza na itching na ntụtụ ahụ, yana iji ogologo oge - lipodystrophy na saịtị ahụ.

Ndị ọzọ: ọzịza, njehie na-ezighi ezi (oge ụfọdụ na mmalite ọgwụgwọ).

Ime na lactation

Enweghị mgbochi ọ bụla maka ịgwọ ọrịa shuga mellitus na insulin n'oge afọ ime, ebe insulin anaghị agafe ihe mgbochi placental. Mgbe ị na-eme atụmatụ ịtụrụ ime na n’oge ya, ọ dị mkpa ime ka ọgwụgwọ shuga dị ike sie ike. Mkpa insulin na-agbadata n'oge ọnwa atọ nke mbụ nke afọ ime wee jiri nwayọ na nke abụọ na nke atọ.

N'oge na mgbe amuchara nwa, ihe ndi choro insulin nwere ike igbadata nke ukwuu. N'oge na-adịghị anya a mụsịrị nwa, mkpa ọ dị insulin na-alaghachi ngwa ngwa dị ka ọ dị tupu ime ime.

Enweghị mgbochi ọ bụla na ọgwụgwọ ọrịa shuga mellitus nwere insulin n'oge a na-enye nwa ara.

Agbanyeghị, ọ nwere ike ịdị mkpa iji belata insulin, yabụ, iji nlezianya nyochaa ọtụtụ ọnwa dị mkpa ruo mgbe ebigharị mkpa insulin dị.

Ntụziaka pụrụ iche

Na-emegide usoro ịgwọ ọrịa insulin, ọ dị mkpa ileba anya mgbe niile itinye uche glucose ọbara.

Ihe kpatara hypoglycemia na mgbakwunye na insulin ịdoụbiga mmanya ókè nwere ike ịbụ: ị replacementụ ọgwụ, nzere nri, vomiting, afọ ọsịsa, mmụba anụ ahụ, ọrịa na-ebelata mkpa insulin (ọrụ imeju na akụrụ na-emebi emebi, hypofunction nke adrenal cortex, pituitary ma ọ bụ thyroid gland), mgbanwe nke nsị, yana iso ọgwụ ndị ọzọ na-emekọrịta ihe.

Singzọ ezighi ezi ma ọ bụ ihe mgbochi na nchịkwa insulin, karịsịa na ndị ọrịa nwere ọrịa shuga 1, nwere ike ibute hyperglycemia. Ọtụtụ mgbe, mgbaàmà mbụ nke hyperglycemia na-amalite nwayọọ nwayọọ karịa ọtụtụ awa ma ọ bụ ụbọchị.

Ndị a gụnyere akpịrị ịkpọ nkụ, mmamịrị nke ukwuu, ọgbụgbọ, ọgbụgbọ, ọgbụgbọ, ọbara ọbara na ajị anụ, akpọnwụ akpịrị, enweghị agụụ, isi nke acetone na ikuku ikuku.

Ọ bụrụ na agwọtaghị ya, hyperglycemia n'ụdị shuga 1 nwere ike ibute mmepe nke ọrịa ketoacidosis na-eyi ndụ egwu.

A ga-emezi ọ̀gwụ insulin ọfụma ọ bụrụ na arụ ọrụ thyroid na-arụ ọrụ, ọrịa Adzison, hypopituitarism, ọrụ imeju na akụrụ, yana ọrịa mellitus n'ime ndị gbara afọ 65.

Ọ dịkwa mkpa iji dozie insulin nke insulin ma ọ bụrụ na onye ọrịa ahụ na-eme ka mmega ahụ sie ike ma ọ bụ gbanwee ụdị nri a na-emebu. Ọrịa concoitant, ọkachasị ọrịa na ọnọdụ ya na ahụ ọkụ na-eme ka ebulite insulin.

Ọkpụkpụ site n'otu ụdị insulin na nke ọzọ ga-ebufe n'okpuru nchịkwa nke ịba ụba nke glucose na ọbara.

Ọgwụ na-ebelata nnabata mmanya.

N'ihi enwere ike iku mmiri na ụfọdụ catheters, anaghị atụ aro ka iji ọgwụ ahụ na nfuli insulin.

Cannweghị ike iji ọgwụ ahụ ma ọ bụrụ na, mgbe amafechara, mmachibido ahụ adịghị ọcha ma ọ bụ na ọ ga-agbanwe.

Mmetụta ikike ịkwọ ụgbọala na usoro njikwa N'ihi ebumnuche insulin, ịgbanwe ụdị ya ma ọ bụ ọnụnọ nke nrụgide anụ ahụ ma ọ bụ nke uche, enwere ike belata ikike ịkwọ ụgbọala ma ọ bụ jikwaa usoro dị iche iche, yana itinye aka na ihe omume ndị ọzọ nwere ike ịdị ize ndụ nke chọrọ mụbara nlebara anya na ọsọ ọsọ nke echiche na moto.

Mkparịta ụka ọgwụ ọjọọ

N ’ogwu ọgwụ ekwekọghị na ọgwụ nke ọgwụ ndị ọzọ. E nwere ọtụtụ ọgwụ na-emetụta mkpa maka insulin.

Mmetụta hypoglycemic nke insulin na-akwalite site na ndị na-abụghị nhọrọ beta-blockers, quinidine, quinine, chloroquinine, monoamine oxidase inhibitors, angiotensin-na-atụgharị enzyme inhibitors, carbonic anhydrase inhibitors, octreotide, bromocriptynefin cyclofenolidolinfenfenfen njikere lithium, nkwadebe nwere ethanol.

Mmetụta hypoglycemic nke insulin na-enyocha ya site na glucagon, somatropin, estrogens, ọgwụ mgbochi, glucocorticosteroids, iodine-nwere homonụ thyroid, thiazide dipotics, loop diuretics, heparin, tricyclic antidepressants, sympathomimetics, epinigin, nje, ọwa calcium, diazoxide, morphine, phenytoin, nicotine.

Reserpine, salicylates nwere ike ịkwalite ma wedata ike hypoglycemic mmetụta nke insulin.

Usoro na ọnọdụ nchekwa

N’ebe gbara ọchịchịrị n ’okpomoku 2 ° C ruo 8 Celsius. Emela ifriizi. Ekwela ka ụmụaka ghara iru ya. Ekwesịrị ịchekwa ọgwụ eji eme ihe na ọnọdụ okpomọkụ 15-25 Celsius C maka ihe na-erughị izu isii.

Exbọchị mmebi. Afọ 2 Ejila oge emechachara edepụtara na ngwugwu.

Vozulim: ntuziaka maka ojiji, ọnụahịa, nyocha na analogues

Edere ọgwụ a maka mmepe nke iguzogide ọgwụ mgbochi hypoglycemic. Ntuziaka maka iji mee ihe dị mkpa iji mee ka onye ọrịa mara nke ọma ọgwụ na omume nke Vozulim.

Usoro usoro onunu ogwu

Ezubere ọgwụ a maka nchịkwa okpuru ala. Ọ bụ dọkịta na-ekpebi ọ̀tụ̀tụ̀ na oge nchịkwa nke ọgwụ ahụ n’otu n’okwu ọ bụla, dabere n’otú glucose dị n’ọbara. Na nkezi, kwa ụbọchị ọgwụ a sitere na 0,5 ruo 1 IU / kg body body (dabere na njirimara nke onye ọrịa na ịba ụba glucose ọbara).

Okpomoku nke mmanu insulin kwesiri ino na okpomoku.

A na-enyekarị ọgwụ a n'okpuru subcutaneously na apata ụkwụ. Enwere ike ịmekwa ya na mgbidi nke oghere ihu, ogwe ma ọ bụ ubu na ịkọwapụta akwara ahụ.

Okwesiri igbanwe ebe ogwu ngbanyere na mpaghara anatomical iji gbochie mmepe nke lipodystrophy.

Enwere ike ijikwa Vozulim-N naanị otu ma ọ bụ na njikọta insulin nke na-adị mkpụmkpụ (Vozulim-P).

Jiri mkpịsị sirinji jiri naanị sirinji.

Njirimara Ngwa:

Jiri n'oge ime na lactation. Enweghị mgbochi ọ bụla maka ịgwọ ọrịa shuga mellitus na insulin n'oge afọ ime, ebe insulin anaghị agafe ihe mgbochi placental. Mgbe ị na-eme atụmatụ ịtụrụ ime na n’oge ya, ọ dị mkpa ime ka ọgwụgwọ shuga dị ike sie ike. Mkpa insulin na-agbadata n'oge ọnwa atọ nke mbụ nke afọ ime wee jiri nwayọ na nke abụọ na nke atọ.

N'oge na mgbe amuchara nwa, ihe ndi choro insulin nwere ike igbadata nke ukwuu. N'oge na-adịghị anya a mụsịrị nwa, mkpa ọ dị insulin na-alaghachi ngwa ngwa dị ka ọ dị tupu ime ime. Enweghị mgbochi ọ bụla na ọgwụgwọ ọrịa shuga mellitus nwere insulin n'oge a na-enye nwa ara. Agbanyeghị, ọ nwere ike ịdị mkpa iji belata insulin, yabụ, iji nlezianya nyochaa ọtụtụ ọnwa dị mkpa ruo mgbe ebigharị mkpa insulin dị.

Na-emegide usoro ịgwọ ọrịa insulin, ọ dị mkpa ileba anya mgbe niile itinye uche glucose ọbara.

Ihe kpatara hypoglycemia na mgbakwunye na insulin ịdoụbiga mmanya ókè nwere ike ịbụ: ị replacementụ ọgwụ, nzere nri, vomiting, afọ ọsịsa, mmụba anụ ahụ, ọrịa na-ebelata mkpa insulin (ọrụ imeju na akụrụ na-emebi emebi, hypofunction nke adrenal cortex, pituitary ma ọ bụ thyroid gland), mgbanwe nke nsị, yana iso ọgwụ ndị ọzọ na-emekọrịta ihe.

Singzọ ezighi ezi ma ọ bụ ihe mgbochi na nchịkwa insulin, karịsịa na ndị ọrịa nwere ọrịa shuga 1, nwere ike ibute hyperglycemia. Ọtụtụ mgbe, mgbaàmà mbụ nke hyperglycemia na-amalite nwayọọ nwayọọ karịa ọtụtụ awa ma ọ bụ ụbọchị. Ndị a gụnyere akpịrị ịkpọ nkụ, mmamịrị nke ukwuu, ọgbụgbọ, ọgbụgbọ, ọgbụgbọ, ọbara ọbara na ajị anụ, akpọnwụ akpịrị, enweghị agụụ, isi nke acetone na ikuku ikuku. Ọ bụrụ na agwọtaghị ya, hyperglycemia n'ụdị shuga 1 nwere ike ibute mmepe nke ọrịa ketoacidosis na-eyi ndụ egwu.

Ekwesịrị idozi ọnụọgụ insulin maka arụ ọrụ thyroid, ọrịa Addison, hypopituitarism, ọrụ imeju na akụrụ na-arịa ya na ọrịa shuga na ndị mmadụ karịa afọ 65.

Ọ dịkwa mkpa iji dozie insulin nke insulin ma ọ bụrụ na onye ọrịa ahụ na-eme ka mmega ahụ sie ike ma ọ bụ gbanwee ụdị nri a na-emebu.

Ọrịa concoitant, ọkachasị ọrịa na ọnọdụ ya na ahụ ọkụ na-eme ka ebulite insulin.

Ọkpụkpụ site n'otu ụdị insulin na nke ọzọ ga-ebufe n'okpuru nchịkwa nke ịba ụba nke glucose na ọbara.

Ọgwụ na-ebelata nnabata mmanya.

N'ihi enwere ike iku mmiri na ụfọdụ catheters, anaghị atụ aro ka iji ọgwụ ahụ na nfuli insulin.

Cannweghị ike iji ọgwụ ahụ ma ọ bụrụ na, mgbe amafechara, mmachibido ahụ adịghị ọcha ma ọ bụ na ọ ga-agbanwe.

Mmetụta ikike ịkwọ ụgbọ ala na usoro nchịkwa. Na njikọta ebumnuche insulin, mgbanwe dị n'ụdị ya ma ọ bụ ọnụnọ nke nrụgide anụ ahụ ma ọ bụ nke uche, enwere ike belata ikike ịkwọ ụgbọala ma ọ bụ ijikwa usoro dị iche iche, yana itinye aka na ihe omume ndị ọzọ dị ize ndụ nke chọrọ nlebara anya na ọsọ nke mmeghachi omume nke uche na moto.

Mlọ ọgwụ

N'iji nnabata edo edo, insulin ritere oke plasma ịta ahụhụ mgbe nchịkwa subcutaneous gasịrị awa 2-18. N'okwu a, ọdịghị ihe dị mkpa na protein protein. Ọgwụ a abanyeghị na Plasenta na n’ime mmiri ara.

Insulinase, protein isomerase ma ọ bụ insulin protease na-enye aka na ndakpọ nke insulin mmadụ, molecule nke nwere ọtụtụ saịtị hydrolysis. N'okwu a, metabolites guzobere na usoro ahụ anaghị arụ ọrụ.

Site na 30 ruo 80% nke ọgwụ ahụ bụ akụrụ. Nkera ndụ bụ 5-10 awa ma dabere na ọnụego mwepu si subcutaneous abụba.

Ntụziaka maka ojiji (usoro na usoro onunu ogwu)

Ebumnuche "Vozulim" bụ iwebata abụba dị n'okpuru ala. Ọ bụ dọkịta na-ahụ maka ịga ọrụ na-ekpebi usoro ị timeụ oge na oge eji ya dabere na ngosipụta nke glucose dị n'ọbara. Dị ka ọ dị, usoro iwu kwa ụbọchị dị iche na 0,5 ruo 1 IU / kg dabere na njirimara onye ọrịa ahụ.

Okpomoku nke ulo nnabata ewebata kwesiri ibu okpomoku. Ebe nlekọta dị larịị bụ akwa dị n'okpuru apata ụkwụ. A na-anabata mpaghara n'ime akwara nke deltoid, a na-anabata mgbidi akụkụ na isi.

DP MARA Achọrọ ịgbanwe saịtị ntụtụ iji oge ụfọdụ iji gbochie lipodystrophy.

A pụrụ ịgwọ ndị ọrịa na-arịa ụdị ọrịa shuga mellitus nke 2 na Vozulim yana ọgwụ hypoglycemic ndị ọzọ (iji ọnụ), yana monotherapy.

Ka Pole Royal

Otu ihe dị mkpa na ndụ nke ọrịa mamịrị ọ bụla bụ mkpịsị sirinji nke insulin. Ihe omumu a na eme ka otutu nde oria n’uwa karia idi ndu. E kwuwerị, ọ bụrụ na mkpịsị akwụkwọ a dị n'aka, onye ọrịa agaghị enwe ike iji enyemaka ndị nọọsụ nweta ọgwụ insulin.

Obere mmịrị na shuga nwere ike ibute ọrịa, yabụ ịzụta injector bụ nzọụkwụ mbụ na ndụ zuru oke.

Mmetụta ọghọm:

N'ihi mmetụta nke metabolism metabolism: ọnọdụ hypoglycemic (pallor nke anụ ahụ, ịba ụba ọsụsọ, palpitations, ịma jijiji, agụụ, oke iwe, paresthesia nke mucosa aral, isi ọwụwa). Nnukwu hypoglycemia siri ike nwere ike iduga mmepe nke hypoglycemic coma.

Mmeghachi omume nfụkasị ahụ: ọnya anụ ahụ, ụbụrụ Quincke, nke a na-adịghị ahụkebe - ujo anacticlactic.

Mmeghachi omume mpaghara: hyperemia, ọria na itching na ntụtụ ahụ, yana iji ogologo oge - lipodystrophy na saịtị ahụ.

Ndị ọzọ - edema, njehie na - ezighi ezi, (oge ụfọdụ na mmalite ọgwụgwọ).

Mmekọrịta na ọgwụ ndị ọzọ:

N ’ogwu ọgwụ ekwekọghị na ọgwụ nke ọgwụ ndị ọzọ.

E nwere ọtụtụ ọgwụ na-emetụta mkpa maka insulin.

Mmetụta hypoglycemic nke insulin na-akwalite site na ndị na-abụghị nhọrọ beta-blockers, quinidine, quinine, chloroquinine, monoamine oxidase inhibitors, angiotensin-na-atụgharị enzyme inhibitors, carbonic anhydrase inhibitors, octreotide, bromocriptynefin cyclofenolidolinfenfenfen njikere lithium, nkwadebe nwere ethanol.

Mmetụta hypoglycemic nke insulin na-enyocha ya site na glucagon, somatropin, estrogens, ọgwụ mgbochi, glucocorticosteroids, iodine nwere homonụ thyroid, ọrịa thiazide, loop diuretics, heparin, tricyclic antidepressants, ọgwụ ọmịiko, ọgwụ nje, ọwa calcium, diazoxide, morphine, phenytoin, nicotine.

Reserpine, salicylates nwere ike ịkwalite ma wedata ike hypoglycemic mmetụta nke insulin.

Ọnọdụ nchekwa:

Chekwaa n'ebe gbara ọchịchịrị na okpomọkụ nke +2 Celsius С ka +8 Celsius. Emela ifriizi. Ekwela ka ụmụaka ghara iru ya. Ekwesịrị ịchekwa ọgwụ eji eme ihe na ọnọdụ okpomọkụ 15-25 Celsius C maka ihe na-erughị izu isii. Ndụ shelf bụ afọ 2. Ejila oge emechachara edepụtara na ngwugwu.

Ọnọdụ ezumike:

Nkwụsịtụ maka nchịkwa okpuru ala nke 100 IU / ml.

3 ml na katriiki iko na-anọpụ iche (ụdị nke m). Akara akara na katriiki. A na-etinye katriiki 1 ma ọ bụ ise na ọnya PVC / aluminom foil.

10 ml na vials nke iko na-anọpụ iche na-enweghị ọ ,ụ ,ụ, ejiri eriri roba mechie ma jiri okpu mkpuchi plastik mee ya.

A na-etinye karama ọ bụla ma ọ bụ ọnya ọ bụla na nọmba pịrịpọ 1 ma ọ bụ nọmba 5 na igbe kaadi na ntuziaka maka ojiji.

Ntuziaka maka iji Protafan NM ka enyere onye ọrịa ahụ

Enwere ike iji vials na ọgwụ Protafan NM mee ihe naanị na sirinji insulin, nke etinyere ọnụ ọgụgụ, nke na-enye ohere ịlele dose ahụ na nkeji nke ime ihe.

Ejiri ọgwụ ọjọọ Protafan NM mee ihe maka ojiji naanị otu onye.

Tupu ịmalite iji karama ọhụrụ nke Protafan HM, a na-atụ aro ka ịhapụ ọgwụ ahụ ka ọ kpoo okpomoku ka ọkụ tupu ebido.

Tupu ị theụ ọgwụ Protafan NM ọ dị mkpa:

1. Lelee ngwugwu iji jide n'aka na ahọpụtara ụdị insulin dị mma.
2. Jiri akwa swim na-eji ahihia eji emebi roba.

Enweghị ike iji ọgwụ Protafan NM mee ihe ndị a:

1. Ejila ọgwụ ahụ na nfuli insulin.
2. Ọ dị mkpa ka ndị ọrịa kọwaa na ọ bụrụ na okpu ọhụrụ a ka natara n'ụlọ ahịa ọgwụ enweghị isi mkpuchi ma ọ bụ na ọ gaghị anọdụ ala, a ga-alaghachi insulin ahụ n'ụlọ ahịa ọgwụ.
3. Ọ bụrụ na echeghị insulin n'ụzọ ziri ezi, ma ọ bụ kpụọ ya oyi.
4. Ọ bụrụ na mgbe ị na-agwakọta ọdịnaya nke vial ahụ dị ka ntuziaka maka ojiji a si arụ ọrụ, insulin anaghị acha ọcha na urukpuru.

Ọ bụrụ na onye ọrịa ahụ na-eji naanị otu ụdị insulin:

1. Ngwa ngwa tupu ịkpọ, kpọghee kalama gị n'ọbụ aka gị ruo mgbe insulin na-acha ọcha ma nwee urukpuru. A na-emeghachite mbugharị ọzọ ma ọ bụrụ na ọgwụ nwere ọnụ ụlọ ahụ.
2. Dọrọ ikuku banye ntụtụ na ọnụego insulin chọrọ chọrọ.
3. Tinye ikuku n'ime oghere nke insulin: maka nke a, a na-eji paịpụ apịpịa apịaji ma jiri piston na-aka.
4. Tụgharịa karama sisa na ihu.
5. Tinye insulin chọrọ chọrọ n'ime sirinji.
6. Wepu agịga na vial ahụ.
7. Wepu ikuku si sirinji.
8. Lelee dose ziri ezi.
9. Gbanye ozugbo.

Ọ bụrụ na onye ọrịa ahụ kwesịrị ịgwakọta Protafan NM na insulin na-eme obere ọrụ:

1. Were akwụkwọ Protafan NM (“urukpuru”) were karama gị mee nkwụ gị ruo mgbe insulin na-acha ọcha ma nwee urukpuru. A na-emeghachite mbugharị ọzọ ma ọ bụrụ na ọgwụ nwere ọnụ ụlọ ahụ.
2. Nyefee ikuku n'ime sirinji na ọnụego kwekọrọ na dose nke Protafan NM (insulin “urukpuru”). Mee ka ikuku banye n’ime vial insulin nke igwe ojii wee wepu agịga na vial ahụ.
3. Denye ikuku n'ime sirinji ya na ọnụego insulin na-eme ka nwa oge (“transperent”). Tinye ọgwụ a iji tinye ikuku n'ime karama. Tụgharịa karama sisa na ihu.
4. Kpoo ọgwụ achọrọ nke insulin na-eme ihe dị mkpirikpi (“doro anya”). Wepụ agịga ma wepụ ikuku si sirinji. Lelee dose ziri ezi.
5. Fanye Protafan HM (insulin “urukpuru”) wee tinye agịga ahụ n'ime pọọsụ ahụ ma jiri sirinji na-agbanye ike.
6. Kpọọ usoro achọrọ nke Protafan NM. Wepu agịga na vial ahụ. Wepu ikuku si na sirinji ma lelee ma ogwu a ziri ezi.
7. Gbaa ngwakọta insulin dị mkpụmkpụ ma dị ogologo ị gbarala.

Gbaa mbọ dọọ ogologo oge na ogologo oge n'otu usoro dị ka akọwara n’elu.

Dụọ onye ọrịa ọdụ ka ịwazie insulin n'otu usoro ahụ a kọwara n’elu.

1. Site na iji mkpịsị aka abụọ, kpoo mkpo anụ, tinye agịga n'ime isi mkpanaka ahụ n'akụkụ ihe dị ka ogo 45, ma gbanye insulin n'okpuru anụahụ.
2. Mgbe ịgba ntụtụ ahụ, agịga kwesịrị ịdị n’okpuru anụ ahụ ma ọ dịkarịa ala 6 sekọnd, iji hụ na etinye insulin ahụ kpamkpam.

Vozulim-N (Vozulim-N) WOCKHARDT (India) nkwusioru maka nchịkwa subcutaneous

Ihe nnọchianya nke inspoglycemic, insulin na-arụ ọrụ nke enwetara site na usoro mkpụrụ ndụ ihe nketa, bụ insulin mmadụ.

Withme ka otu onye nnabata nke akpụkpọ ahụ dị na sel na - emekọ ihe, na - eme ka ihe nnabata nke insulin. Site na ịba ụba njikọta nke cAMP (na abụba abụba na akwara akwara) ma ọ bụ banye n’ime sel (akwara), insulin receptor complex na-akpali usoro intracellular, gụnyere njikọ nke ọtụtụ enzymes isi (gụnyere hexokinase, pyruvate kinase, glycogen synthetase).

A na-eme ka mbelata glucose na ọbara na-abawanye site na mmụba na ntinye ya n'ime intracellular, nnabata nke ukwuu na nnweta nke anụ ahụ, mkpali nke lipogenesis, glycogenogenesis, njikọ protein, yana mbelata nke mmịpụta glucose site na imeju (ibelata na mmebi nke glycogen).

Mwepu na mmalite nke ihe ahụ dabere n'okporo ụzọ nchịkwa (sc ma ọ bụ intramuscularly), ọnọdụ (afọ, apata ụkwụ, isi) na olu ịgba ọgwụ, ịta insulin na ọgwụ. A na-ekesasị ya na akwara na - ekwekọghị n ’ụzọ anụ ahụ, ọ banyeghị n’ihe mgbochi placental ma banye n’ime mmiri ara. Insulinase bibiri ya, ọkachasị na imeju na akụrụ. Ọ bụ ya bụ akụrụ (30-80%).

Elldị shuga shuga shuga Type 2 mellitus: ọkwa nke iguzogide ndị ọrịa hypoglycemic nke nwoke, iguzogide ele mmadụ anya n’ihu ọgwụ ndị a (n’oge ọgwụgwọ), ọrịa shuga, ụdị shuga mellitus nke 2 n’ime ụmụ nwanyị dị ime.

N'ihi mmetụta nke metabolism metabolism: ọnọdụ hypoglycemic (pallor nke anụ ahụ, ịba ụba ọsụsọ, palpitations, ịma jijiji, agụụ, oke iwe, paresthesia n'ọnụ, isi ọwụwa). Nnukwu hypoglycemia siri ike nwere ike iduga mmepe nke hypoglycemic coma.

Mmeghachi omume nfụkasị ahụ: ọ na - adịkarịghị - ọnya anụ ahụ, ọnya Quincke, nke a na - adịghị ahụkebe - ujo anacticlactic.

Ndị ọzọ: edema, njehie na - ebugharị ebumnuche (ọ na - abụkarị mmalite nke ọgwụgwọ).

Mmeghachi omume mpaghara: hyperemia, ọria na itching na ntụtụ ahụ, yana iji ogologo oge - lipodystrophy na saịtị ahụ.

Tinye s / c, 1-2 ugboro / ụbọchị, nkeji 30-45 tupu nri ụtụtụ. Ekwesịrị ịgbanwe saịtị nsị ahụ oge ọ bụla. N'ọnọdụ ndị pụrụ iche, ntinye okwu / m ga-ekwe omume.

Anabataghị / na iwebata insulin nke ọkara oge.

A na-edowe doses n'otu n'otu, dabere na ọdịnaya nke glucose dị n'ọbara na mmamịrị, njirimara nke ụzọ ọrịa ahụ.

Ọrịa: mmepe nke hypoglycemia (ọsụsọ oyi, palpitations, ụjọ, agụụ, oke iwe, mgbakasị ahụ, isi ọwụwa, isi ọwụwa, enweghị mmegharị, enweghi ike ikwu okwu na ọhụhụ, obi ụfụ).Nnukwu hypoglycemia nwere ike ibute mmebi nke ọrụ ụbụrụ, coma, na ọnwụ ruo nwa oge ma ọ bụ nke na-adịgide adịgide.

Ọgwụgwọ: shuga ma ọ bụ ihe glucose dị n’ime (ọ bụrụ na onye ọrịa maara), s / c, i / m ma ọ bụ iv - glucagon ma ọ bụ iv - glucose.

Udoro maka ochichi sc.

10 ml - karama iko (1) - igbe kaadiboodu.
3 ml - katọn (1) - ngwugwu na-acha uhie uhie (1) - ngwugwu nke kaadiboodu.

Mmetụta hypoglycemic bụ nke sulfonamides na-eme ka ọ dịkwuo mma (gụnyere ndị na-ahụ maka hypoglycemic onu, sulfanilamides), MAO inhibitors (gụnyere furazolidone, procarbazine, selegiline), carbon anhydrase inhibitors, ACE inhibitors, ndị na-elekọta NSAIDs (gụnyere NSAIDs)

salicylates), anabolic steroid (gụnyere

stanozolol, oxandrolone, methandrostenolone), androgens, bromocriptine, tetracyclines, clofibrate, ketoconazole, mebendazole, theophylline, cyclophosphamide, fenfluramine, njikere lithium, pyridoxine, quinidine, quinine, chloroquin.

Glucagon, somatropin, GCS, mgbochi mgbochi nke ọnụ, estrogens, thiazide na “loop” diuretics, ndị na-egbochi calcium, homonụ thyroid, heparin, sulfin pyrazone, sympathomimetics, danazole, tricyclic antidepressants, calcium chloride, moron, belata mmetụta hypogly. nicotine, phenytoin, epinephrine, histamine H1 na-egbochi ihe mgbochi.

Beta-blockers, reserpine, octreotide, pentamidine nwere ike ịkwalite ma belata mmetụta hypoglycemic nke insulin.

Azu ọgwụ ekwekọghị na ngwọta na ọgwụ ndị ọzọ.

Ọ dị mkpa ịgbanwe ebe a na-agba agba gburugburu mpaghara anatomical iji gbochie mmepe nke lipodystrophy.

Na-emegide usoro ịgwọ ọrịa insulin, ọ dị mkpa ịdị na-achọpụta ọ̀tụ̀tụ̀ glucose ọ̀tụ̀tụ̀ ọbara mgbe niile.

Ihe ndị na - akpata hypoglycemia, na mgbakwunye na insulin ịdoụbiga mmanya ókè, nwere ike ịbụ: nnọchi ọgwụ, nzere nri, vomiting, afọ ọsịsa, mmega ahụ na-abawanye ụba, ọrịa na-ebelata mkpa insulin (ọrụ imeju na akụrụ, hypofunction nke adrenal cortex, pituitary ma ọ bụ thyroid gland), mgbanwe nke ebe yana inje, yana iso ogwu ndi ozo.

Ọgwụ na-adịghị mma ma ọ bụ nkwụsịtụ n'ime nchịkwa insulin, karịsịa na ndị ọrịa nwere ọrịa shuga 1, nwere ike ibute hyperglycemia. Ọtụtụ mgbe, mgbaàmà mbụ nke hyperglycemia na-amalite nwayọọ nwayọọ karịa ọtụtụ awa ma ọ bụ ụbọchị.

Ndị a gụnyere akpịrị ịkpọ nkụ, mmamịrị nke ukwuu, ọgbụgbọ, ọgbụgbọ, ọgbụgbọ, ọbara ọbara na ajị anụ, akpọnwụ akpịrị, enweghị agụụ, isi nke acetone na ikuku ikuku.

Ọ bụrụ na agwọtaghị ya, hyperglycemia n'ụdị shuga 1 nwere ike ibute mmepe nke ọrịa ketoacidosis na-eyi ndụ egwu.

Ekwesịrị imeghari etu insulin si arụ ọrụ ọfụma, ọrịa nke Addison, hypopituitarism, ọrụ imeju na akụrụ ya na ọrịa mellitus na ndị ọrịa karịrị afọ 65. Alsogbanwe uda insulin nwekwara ike ịchọ ma ọ bụrụ na onye ọrịa ahụ na-eme ka mmega ahụ sie ike ma ọ bụ gbanwee ụdị nri a na-emebu.

Ọrịa concoitant, ọkachasị ọrịa na ọnọdụ ya na ahụ ọkụ na-eme ka ebulite insulin.

Ọkpụkpụ site na ụdị insulin na nke ọzọ ga-ebufe n'okpuru ịchịkwa ọkwa glucose ọbara.

Ọgwụ ahụ na-ebelata mmanya nnabata.

Na njikọta ebumnuche insulin, mgbanwe dị n'ụdị ya ma ọ bụ ọnụnọ nke nrụgide anụ ahụ ma ọ bụ nke uche, enwere ike belata ike ịkwọ ụgbọala ma ọ bụ ijikwa usoro dị iche iche, yana itinye aka na ihe omume ndị ọzọ dị ize ndụ nke chọrọ nlebara anya na ọsọ nke mmeghachi omume nke uche na moto.

N'oge afọ ime, ọ dị mkpa iburu n'uche mbelata mkpa nke insulin na ọkara nke mbụ ma ọ bụ mmụba nke ọnwa nke abụọ na nke atọ. N'oge na mgbe amuchara nwa, ihe ndi choro insulin nwere ike igbadata nke ukwuu.

N'oge a na-enye nwa ara, a na-achọ nlele kwa ụbọchị ruo ọtụtụ ọnwa (ruo mgbe a gbanwere mkpa insulin).

Mkpa insulin nwere ike ịdị iche na ọrịa imeju.

Mkpa insulin nwere ike ịdị iche na ọrịa akụrụ. Requiredmeghari insulin dose choro na ọdịda akụrụ afọ.

Vozulim-N (Vozulim-N) WOCKHARDT (India) nkwusioru maka nchịkwa subcutaneous

Vozulim-n - ntuziaka maka ojiji na Yandex.Health

Na-emegide usoro ịgwọ ọrịa insulin, ọ dị mkpa ileba anya mgbe niile itinye uche glucose ọbara.

Ihe kpatara hypoglycemia na mgbakwunye na insulin ịdoụbiga mmanya ókè nwere ike ịbụ: ị replacementụ ọgwụ, nzere nri, vomiting, afọ ọsịsa, mmụba anụ ahụ, ọrịa na-ebelata mkpa insulin (ọrụ imeju na akụrụ na-emebi emebi, hypofunction nke adrenal cortex, pituitary ma ọ bụ thyroid gland), mgbanwe nke nsị, yana iso ọgwụ ndị ọzọ na-emekọrịta ihe.

Singzọ ezighi ezi ma ọ bụ ihe mgbochi na nchịkwa insulin, karịsịa na ndị ọrịa nwere ọrịa shuga 1, nwere ike ibute hyperglycemia. Ọtụtụ mgbe, mgbaàmà mbụ nke hyperglycemia na-amalite nwayọọ nwayọọ karịa ọtụtụ awa ma ọ bụ ụbọchị.

Ndị a gụnyere akpịrị ịkpọ nkụ, ure ugboro ugboro, ọgbụgbọ, ọgbụgbọ, ọgbụgbọ, ọbara ọbara na ajị anụ, akpịrị ịkpọ nkụ, agụụ, agụụ nke acetone na ikuku nwere oke.

Ọ bụrụ na agwọtaghị ya, hyperglycemia n'ụdị shuga 1 nwere ike ibute mmepe nke ọrịa ketoacidosis na-eyi ndụ egwu.

Ekwesịrị imeghari dose insulin na arụ ọrụ thyroid, ọrịa Addison, hypopituitarism, ọrụ imeju na akụrụ, yana ọrịa mellitus na ndị ọrịa karịa afọ 65.

N'ihi ohere dị ukwuu nke ọrịa obi na ọrịa ụbụrụ nke hypoglycemia, ekwesịrị iji nkwadebe insulin na-akpachara anya na ndị ọrịa nwere nnukwu akarị akwara na akwara.

Iji nlezianya na ndị ọrịa nwere ọrịa retinopathy na-abawanye uru, ọkachasị na-enwetaghị ọgwụgwọ na photocoagulation (coagulation laser) n'ihi ihe egwu amaurosis (ikpu ìsì zuru oke).

Ọ bụrụ na onye ọrịa ahụ na-eme ka imega ahụ dịkwuo ukwuu ma ọ bụ gbanwee ụdị nri ha na-emebu, ọ ga-adị mkpa ịgbanwe mgbanwe insulin.

Ọrịa concoitant, ọkachasị ọrịa na ọnọdụ ya na ahụ ọkụ na-eme ka ebulite insulin.

Transferbufe onye ọrịa na ụdị insulin ọ bụla ma ọ bụ ịkwadebe insulin nke onye nrụpụta ọzọ ga-emerịrị n'okpuru nlekọta nke dibia.

Mgbe ị na-eji nkwadebe insulin yana ọgwụ ọgwụ thiazolidinedione, ndị ọrịa nwere ụdị ọrịa shuga mellitus 2 nwere ike ịnwe njigide mmiri, nke na-abawanye n'ihe ize ndụ nke ịmalite ma na-aga n'ihu na nkụda mmụọ na-adịghị ala ala, karịsịa na ndị ọrịa nwere ọrịa nke usoro obi na ọnụnọ nke ihe ndị dị ize ndụ maka ala ala obi obara. Ekwesịrị inyocha ndị ọrịa na-enweta ọgwụgwọ dị otú ahụ mgbe niile iji chọpụta ihe ịrịba ama nke nkụda obi. Ọ bụrụ na nkụchi obi na-eme, a ga-ebu ọgwụgwọ dịka usoro ọgwụgwọ ugbu a. N'okwu a, ọ dị mkpa ịtụle ohere ịnwe ma ọ bụ belata dose nke thiazolidinedione.

- ụdị shuga 1

- ụdị shuga mellitus nke 2: ogbo nke nguzogide ọgwụ hypoglycemic nke ọnụ, nguzogide ele mmadụ anya na ọgwụ ndị a (n'oge ọgwụgwọ njikọta), ọrịa na - efe efe,

- Pịnye ọrịa shuga dị afọ abụọ n’ime ụmụ nwanyị dị ime.

Nkwụsị maka njikwa SC

- mụbawanye uche na insulin ma ọ bụ ihe ọ bụla nke ọgwụ ahụ.

Usoro usoro onunu ogwu

Emere ọgwụ a maka sc አስተዳደር naanị. Ọ bụ dọkịta ga-ekpebi ọ̀tụ̀tụ̀ ọgwụ ahụ n’otu n’otu n’otu, dabere n’ịchịkọta glucose dị n’ọbara.

Na nkezi, kwa ụbọchị ọgwụ a sitere na 0,5 ruo 1 IU / kg body body (dabere na njirimara nke onye ọrịa na ịba ụba glucose ọbara).

Ndị ọrịa agadi na-anata insulin ọ bụla, gụnyere Vosulim-H, nọ n'ihe ize ndụ ịbawanye ụba nke hypoglycemia n'ihi ọnụnọ nke ọnya na-efe efe na n'otu oge nke ọtụtụ ọgwụ. Ọ nwere ike ịdị mkpa ịgbanwe nhazi nke insulin.

Ndị ọrịa nwere akụrụngwa akwara na arụ ọrụ hepatic nọ n'ihe ize ndụ nke hypoglycemia ma chọọ mgbanwe insulin dose na nleba anya ọzọ nke glucose ọbara.

Ogologo oge insulin nke mmadu nwetara site na iji teknụzụ di omimi nke DNA.

Ọ na - emekọrịta otu onye na - anabata ihe n'ụsọ akpụkpọ ahụ cytoplasmic nke mkpụrụ ndụ ma mepụta ogige insulin-receptor na-akpali usoro intracellular, gụnyere njikọ nke ọtụtụ isi enzymes (hexokinase, pyruvate kinase, glycogen synthetase).

Mbelata nke glucose n'ime ọbara bụ n'ihi mmụba na ntinye ya dị n'ime ala, mmụba dị ukwuu na njigide anụ ahụ, mkpali nke lipogenesis, glycogenogenesis, na mbelata ọnụego glucose na-emepụta site na imeju.

Ogologo oge nke ihe insulin na-eme bu n'ihi nzere nke mmiri, nke dabere na otutu ihe (dika ima atu, uzo ya na ebe ochichi ya), ya mere profaịlụ nke insulin n’ariri mgbanwe di omimi, ma n’ebe ndi mmadu di iche na otu mmadu.

Na nkezi, mgbe sc nchịkwa, ọ na-amalite ime ihe mgbe awa 1.5 gachara, nsonaazụ kachasị na-ebido n'agbata awa anọ na awa iri na abụọ, ogologo oge nke ihe ahụ ruru awa 24.

Mmetụta dị n'akụkụ nsonaazụ n'ihi metabolism metabolism: ọnọdụ hypoglycemic (pallor nke anụ ahụ, ịba ụba, nrịanrịa, ịma jijiji, agụụ, oke iwe, paresthesia nke mucosa onral, isi ọwụwa, nkụda mmụọ, belata acuity visual). Nnukwu hypoglycemia siri ike nwere ike iduga mmepe nke hypoglycemic coma.

Mmeghachi omume nfụkasị ahụ: ọnya anụ ahụ, ọnya nke Quincke, ujo anafilactic.

Mmeghachi omume mpaghara: hyperemia, ọria na itching na ntụtụ ahụ, yana iji ogologo oge - lipodystrophy na saịtị ahụ.

Ndị ọzọ: edema, mbelata oge na acuity visual (oge ụfọdụ na mmalite ọgwụgwọ).

Ekwesịrị ịgwa onye ọrịa ahụ na ọ bụrụ na ọ chọpụta mmepe nke hypoglycemia ma ọ bụ nwee ọhụhụ nke mmụọ, ọ kwesịrị ịgwa dọkịta ozugbo.

Ọ bụrụ n ’akụkụ ndị ọzọ ọ bụla akọwapụtaghị n’elu, onye ọrịa ahụ kwesịkwara ịga hụ dọkịta.

Ekwesighi iji ọgwụ a ma ọ bụrụ na, mgbe ịma jijiji gasịrị, nkwusioru ahụ apụtaghị ọcha na igwe ojii.

Na-emegide usoro ịgwọ ọrịa insulin, ọ dị mkpa ileba anya mgbe niile itinye uche glucose ọbara.

Ihe kpatara hypoglycemia na mgbakwunye na insulin ịdoụbiga mmanya ókè nwere ike ịbụ: ị replacementụ ọgwụ, nzere nri, vomiting, afọ ọsịsa, mmụba anụ ahụ, ọrịa na-ebelata mkpa insulin (ọrụ imeju na akụrụ na-emebi emebi, hypofunction nke adrenal cortex, pituitary ma ọ bụ thyroid gland), mgbanwe nke nsị, yana iso ọgwụ ndị ọzọ na-emekọrịta ihe.

Ọgwụ na-adịghị mma ma ọ bụ nkwụsịtụ n'ime nchịkwa insulin, karịsịa na ndị ọrịa nwere ọrịa shuga 1, nwere ike ibute hyperglycemia. Ọtụtụ mgbe, mgbaàmà mbụ nke hyperglycemia na-amalite nwayọọ nwayọọ karịa ọtụtụ awa ma ọ bụ ụbọchị.

Ndị a gụnyere ọdịdị nke akpịrị ịkpọ nkụ, urination ngwa ngwa, ọgbụgbọ, ọgbụgbọ, ọgbụgbọ, ọbara ọbara na nkụ, akpịrị ịkpọ nkụ, agụụ, agụụ nke acetone na ikuku nwere ume.

Ọ bụrụ na agwọtaghị ya, hyperglycemia n'ụdị shuga 1 nwere ike ibute mmepe nke ọrịa ketoacidosis na-eyi ndụ egwu.

Na njikọta ebumnuche insulin, mgbanwe dị n'ụdị ya, ma ọ bụ ọnụnọ nke nrụgide anụ ahụ ma ọ bụ nke uche, enwere ike belata ikike ịkwọ ụgbọala ma ọ bụ usoro dị iche iche, yana itinye aka na ọrụ ndị ọzọ dị ize ndụ nke chọrọ nlebara anya na ọsọ nke mmeghachi ..

E nwere ọtụtụ ọgwụ na-emetụta mkpa maka insulin.

Hypoglycemic mmetụta nke insulin welie onu hypoglycemic ọgwụ ọjọọ, Mao inhibitors, Ace inhibitors, carbonic anhydrase inhibitors, nhọrọ beta-blockers, bromocriptine, octreotide, sulfonamides, anabolic Steroid, tetracyclines, clofibrate, ketoconazole, mebendazole, pyridoxine, theophylline, cyclophosphamide, fenfluramine, lithium preparations nkwadebe nwere ethanol.

Mmetụta hypoglycemic nke insulin na-enyocha site glucagon, somatropin, estrogens, ọgwụ mgbochi, corticosteroids, iodine nwere homonụ thyroid, thiazide diuretics, “loop” diuretics, heparin, tricyclic antidepressants, ọgwụ na-enye obi ụtọ, ọgwụ na-anwụ anwụ, ọgwụ na-acha odo odo, na-eji ọgwụ, na-agbakori, na-anata, na-agbakori, na-anata, na-agbakori, na-anata, na-agbakwu, , diazoxide, morphine, phenytoin, nicotine.

N'okpuru mmetụta nke reserpine na salicylates, ma ike na-agwụ ike ma na-abawanye na ọrụ ọgwụ a ga-ekwe omume.

Kedu ụdị sirinji enwere?

N'ihe banyere ọrịa shuga mellitus, usoro metabolic na-eji nwayọọ nwayọọ eme ahụ mmadụ n'ihi malfunctions na njikọ nke insulin. Ọgwụ maka ọrịa shuga 1 na-emetụta nchịkwa nke homonụ. Edebere egbe sirinji maka nchịkwa ọgwụ ngwa ngwa n'ime ahụ ma ọ bụrụ na oge mberede. Enwere otutu injectors dị iche iche:

• Sirinji dabere na agịga ewepụ. Ọdịiche nke ọrụ mkpịsị akwụkwọ bụ na onye ọrịa ahụ kwesiri itinye obere agịga ọ bụla oge tupu ya theụọ ọgwụ ma were ya nye ya.
• Sirinji nwere agịga ejiri. Ejiri ụdị ngwaọrụ a na agịga ahụ nwere nke akpọrọ "mpaghara nwụrụ anwụ", nke na-ebelata ohere ịbelata insulin.

Etu ị ga-esi họrọ pen sirinji maka insulin?

Ekere insulin egbe ọ bụla maka ndị ọrịa mamịrị iji mezuo ihe niile achọrọ maka ndị ọrịa nwere ọrịa shuga.

E kwesịrị ime piston nke aka ahụ n’ụzọ ga-akachasị mfe iji injector na-enweghị ihe mgbu. Mgbe ịzụrụ sirinji insulin, ọ dị mkpa ị attentiona ntị na ogo ngwaọrụ ahụ.

Shouldkwesịrị ịhọrọ ọkụ nro nro na ịdị arọ, ejiri ya na mgbama ụda nke enyere na mgbe a gbanyere homonụ ahụ.

Dọkịta na-ahọrọ usoro ị theụ ọgwụ ahụ, ọtụtụ mgbe ha na-ekwupụta na ụmụaka 0,5 na ụmụ, otu 1 na ndị okenye.

"Protafan NM Penfil"

Anabatara iji naanị maka iji ọgwụ dị okirikiri, amachibido ịbanye n'ime ya. A na-atụ aro ịgbanwe saịtị ntụtụ oge ọ bụla.

Nkewa ahu emere dika insulin nwere otutu onwonso. Dị na katrized ise. Mgbe ọ bụla ejiri Protafan, ọ dị mkpa ijide n’aka na ewepụrụ agịga na sirinji pen.

Ma ọ bụghị ya, ọgwụ ahụ nwere ike ịwụsị, nke dị ize ndụ site na ịgbanwe ịta ya.

Rinsulin R

Nkwadebe Rinsulin NPH bụ maka emegharị emegharị. Nweghị ike gbanye ọgwụ ahụ ma ọ bụrụ na ọ na-akpị. Nweta ihe ahụ site na njikọ, nwere oge dị mkpirikpi. Dakọtara maka iji RinAstra ahụ. Ọ na - arụ ọrụ naanị ma ọ bụrụ na ihe ahụ erutela temprechọ nke ụlọ.

“Ka na-ebu Royal N”

Iji duzie insulin, ịchọrọ Wozulim Pen Royal injectionor. Ọgwụ na-agwakọta insulin na-agakọ ogologo oge na nke dị mkpirikpi. A na-atụ aro ka o jiri nlezianya na ndị ọrịa nwere ọrịa akụrụ. Enwere ike iji ya n'oge ime, ọgwụ ahụ anaghị agafe Plasenta. Ogologo oge nke nkwusara ahụ bụ awa 24.

Rosinsulin

Mkpịsị sirinji eji emegharị emegharị "Rosinsulin Nkasi Obi Pen" nwere ikpehe rọba pere mpe. Onye ọrụ nwere ike ịhazigharị ọnụọgụ, ngwaọrụ ahụ na-agụnye wiil dị nro maka setịpụtara ngwaọrụ.

Ngwaọrụ ahụ nwere nkewa doro anya nke nwere nkeji 60. Ezigbo maka ndị nwere ọhụụ dị ala. Ezubere mkpịsị odere bụ maka ọtụtụ ojiji na-enwe ike ịgbanwe katrij.

Onwere ohere igbanwe udiri ederede ezighi ezi. Agụnyere bụ ntụziaka.

BiomaticPen

Aka a di iche na ndi ozo ndi ozo n’eji ihe ozo di nma nke nwere agwara di nkpa, nke n’enwe obere ihe mgbu.

BiomatikPen dị mma maka Biosulin, enwere ike ịzụta ya na ụlọ ahịa pụrụ iche ma ọ bụ na ndepụta ntanetị.

Ngwaọrụ a nwere igwe elektrik na-akpaghị aka na-egosipụta usoro nke ọgwụ a nyere. Tupu ịbanye "Biosulin", ị ga-agụ ntụziaka ndị a.

HumaPen Savvio

Edere mkpụrụ akwụkwọ sirinji “Humapen Savvio” bụ maka nnweta insulin na-arịa ndị ọrịa mamịrị. Ihe puru iche bu ihe eji abanye injection.

Ejiri aluminom mee ngwaọrụ ahụ, na-eguzogide mmebi mebiri emebi na ntanetị na ikpe ahụ. Zuru ezu na ikpe na-abịa n’akpa uwe nwere ike ịnabata ihe ọ chọrọ 6. Odikwa na otutu agba.

Ejiri igwe na - eme ihe eji eme ya na ihuenyo

Autopen kpochapụwo

Gunpenus reusable insulin gun kwekọrọ na ụdị insulin dị iche iche, dịka Biosulin, Rosinsulin na ndị ọzọ.

Enwere ike iji ngwaọrụ Avtopen jiri obere agịga niile nwere ike iji rụọ ọrụ. Mkpịsị mkpụrụ osisi sigpen Autopenpen gụnyere: ihe na-enye ihe, ihe dị nro, agịga agịga atọ (8 mm) na ngwaọrụ onwe ya.

A na-atụ aro ka ị gụọ ntuziaka ahụ tupu ojiji.

Ọdịdị nke égbè insulin mere ka ndụ ndị ọrịa shuga dịrị ndụ mfe, a naghị enwekwa pensụl sirinji SoloStar. Ndị a bụ ngwaọrụ insulin disposable.

Ezubere maka ojiji nkeonwe naanị iji zere ibute ọrịa. Ọkpụkpụ ọ bụla chọrọ iji agịga ọhụrụ, nke a ga-etinye ya tupu iwebata insulin.

Mgbe ejiri ya, ejiri okpu mechie aka ahụ, a na-ebu ụzọ wepụ agịga ahụ. Ejiri insulin "Insuman Comb 25" mee ihe.

Humulin ngwa ngwa Pen

Ndenye ngwa ngwa QuickPen abụghị nke ewu ewu na ndị ọzọ na-emepụta. Kwesịrị ekwesị maka ụmụ nwanyị dị ime nwere ụdị shuga 2. Autopenpen pensụl pensụl na Humulin Rapid bụ ndị isi ahịa.

N'adịghị ka nhọrọ nke mbụ, a na-atụfu akwụkwọ nke QuickPen, nke nwere oge Humalog. Mgbe ọ bụla ojiji Humulin, a na-atụfu ngwaọrụ ahụ, pensụl chọrọ ịgbanwe.

Ngwunye ahụ nwere pensụl 5 nke 3 ml nke ihe ngwọta na nke ọ bụla.

Njirimara nke sirinji pen

Otu njiri mara nke ụdị ngwaọrụ a bụ na maka iwebata ụdị insulin dị iche iche, ị gaghịzị achọ enyemaka nke ndị bịara abịa. N’okwu nke mbụ, katọn a na-eji tụfuo ga-ewe ihe dịka ụbọchị iri atọ, ma emesịa tụfuo ya.

Na nke abụọ - ngwaọrụ ndị eji emegharị emegharị nwere katriji nke na-enye mkpịsị ode akwụkwọ ogologo oge ruo afọ 3. Otu ihe dị mkpa bụ na ndị na-emepụta na-ewepụta mkpịsị akwụkwọ na katriiki nke otu ụdị, yabụ, iji zere nsonaazụ a na-atụghị anya ya, ọ ka mma ịzụta akụkụ abụọ nke ngwaọrụ nke otu usoro.

Ma ọ bụghị ya, obere ihe ma ọ bụ karịa na-abanye ahụ.

Atụmatụ achọrọ

Otu n'ime njiri mara njiri mara mkpịsị amụ kwesịrị inwe. A na-atụle nhọrọ kachasị mma mgbe egbe injection enweghị ihe karịrị 10 PIECES, ebe a na-eme akara ahụ n'ụzọ nke na ọnụahịa otu àgwà bụ 0.25 PIECES.

Ọ dị mkpa ị attentiona ntị na ọdịdị nke ngwaọrụ ahụ. Nkewa nke obula kwesiri inwe uzo di anya n’ebe ibe ha no ka onye oria ghara inwe nsogbu na nha nke ogwu.

Nke a bụ eziokwu karịsịa maka ndị agadi na ndị ọrụ nwere nsogbu anya.

Etu esi eji ya?

Tupu ịzụta ngwaọrụ, ọtụtụ mmadụ na-eche etu ọ ga-esi dị mma iji ya na ndụ ụbọchị. Ọ bụghị mmadụ niile nwere ike ịchọrọ onwe ha, na-enweghị enyemaka nke ndị na-apụ apụ, mepụta usoro maka ịbanye insulin, gbanye mmanụ dị dochie anya. Dọkịta kwesịrị ịkọwa onye ọrịa ahụ ka esi eji mkpịsị akwụkwọ ahụ rụọ ọrụ ọfụma.

Tupu ntụtụ ahụ, ịkwesịrị iji ihe dị ka nkeji iri na abụọ. Aka ahụ na-agbagharị ogo 180. Emere nke a ka agwakọta ọdịnaya nke egbe na katriiki. Windo nwere ụzọ dị n'ime ahụ nke ngwaọrụ ahụ, nke na-enyere onye ọrịa aka ịnyagharịa na usoro edobere.

Iji gbanye insulin n'okpuru anụ ahụ, a na-enweta bọtịnụ ma mgbe sekọnd iri gasịrị, a na-ewepụ agịga ahụ n'ahụ.

Kedu agịga ndị a na-eji?

Mgbe ị na-ahọrọ ngwaọrụ, ọ dịkwa mkpa ị attentiona ntị n'ịdị mma nke agịga, n'ihi na maka inulin insulin na nke a bụ nnukwu ihe dị mkpa. Ogo ogo ihe mgbu n’oge nlekọta ọgwụ na-adabere n’otú agịga dị nkọ.

Na ire ere nwere agịga nke oke dị iche iche, nke na-eme ka o kwe omume na-ebu inje na-enweghị ihe ize ndụ ịbanye na anụ ahụ.

Ọ bụ ihe dị mkpa ịzụta agịga 4-8 mm ogologo n'ihi na ha dị gịrịrị, nke a na-emekwa ka nchịkwa nke ọgwụ ahụ dịkwuo mma.

Enyere ozi a maka omuma ozi niile ma o ghaghi iji ya. Ejila onwe gi ogwu, o nwere ike idi nsogbu. Gwa dọkịta mgbe niile. N'ọnọdụ nke kọọ ma ọ bụ jupụta ihe niile sitere na saịtị ahụ, achọrọ njikọ na ya.

Ọnọdụ nchekwa Vosulin Pen Royal insuline sirinji

Mee ka ụmụaka ghara iru.

Udoro maka ochichi sc.

10 ml - karama iko (1) - igbe kaadiboodu.
3 ml - katọn (1) - ngwugwu na-acha uhie uhie (1) - ngwugwu nke kaadiboodu.

Maka sc አስተዳደር naanị. Ọ bụ dọkịta ga-ekpebi ọ̀tụ̀tụ̀ ọgwụ ahụ n’otu n’otu n’otu, dabere n’ịchịkọta glucose dị n’ọbara.

N’ihe dị ka mkpụrụ ndụ kwa ụbọchị, o toro site na ịdị arọ 0,5 ruo 1 IU / n'arọ (dabere na njirimara onye ọrịa na ịba n'ọbara nke ọbara).

Mmetụta dị n'akụkụ nsonaazụ n'ihi metabolism metabolism: Ọnọdụ hypoglycemic (pallor nke anụ ahụ, ịba ụba ọsụsọ, palpitations, ịma jijiji, agụụ, oke iwe, paresthesia nke mucosa a na-ede ede, isi ọwụwa, dizzness, visual acuity belata). Nnukwu hypoglycemia siri ike nwere ike iduga mmepe nke hypoglycemic coma.

Mmeghachi omume nfụkasị ahụ: nsị anụ ahụ, edere nke Quincke, ujo anaphylactic.

Mmeghachi omume mpaghara: hyperemia, ọzịza na itching na ntụtụ ahụ, yana iji ogologo oge - lipodystrophy na saịtị ahụ.

Ndị ọzọ: ọzịza, mbelata oge na acuity visual (ọ bụkarị na mmalite ọgwụgwọ).