AMIX vet HTTs (AMIX vet STS)

Ihe ngosi maka ojiji:

Ọrịa shuga diabetesdị nke abụọ, nke enwere ike ịkwado shuga ọbara nke ọma site na ịbelata oke, nri, na mmega ahụ.

A na-ekpebi ogo ọgwụ a dabere na nsonaazụ nke ọbara na ule mmamịrị maka shuga. Usoro mbụ nke ọgwụ bụ 1 mg nke glimepiride 1 oge kwa ụbọchị. Mgbe enwetara nlezianya banyere ọnọdụ onye ọrịa ahụ, a na-eji ọgwụ a dị ka ọgwụgwọ na-akwado ya. Ọ bụrụ na enweghị ike ijikwa ọnọdụ afọ ojuju nke onye ọrịa ahụ, ekwesịrị ịbawanye dose ahụ (dabere na nsonaazụ nchịkwa glycemic) gaa 2 mg, 3 mg ma ọ bụ 4 mg nke glimepiride kwa ụbọchị 1 ruo izu abụọ.

Anweta glimepiride karịa 4 mg kwa ụbọchị na-enye mmụba naanị n'ọnọdụ ndị pụrụ iche, edepụtara ya kpamkpam. Ogo kachasị akwadoro bụ 6 mg nke glimepiride kwa ụbọchị.

N'ime ndị ọrịa bụ ndị iji oke ọgwụ ọgwụ metformin kwa ụbọchị emeghị ka ọ nweta ụgwọ ọrụ afọ ojuju nke metabolism metabolism, enwere ike ịmalite ọgwụgwọ glimepiride na-agbanwe agbanwe. A ga-ahapụrụ dose nke metformin na otu ọkwa ahụ, ma ọgwụgwọ glimepiride kwesịrị ịmalite site na iji usoro dị ala, nke a ga-eji nwayọ belata ruo na oke kachasị kwa ụbọchị, dabere na nkwụghachi ụgwọ metabolic chọrọ. Ekwesịrị ịmalite ọgwụgwọ dị otú ahụ n'okpuru nlekọta nke dọkịta.

N’ebe ndị ọrịa na-anabataghị metabolism ọ bụla ọbụna mgbe ha carbohydụsịrị oke ọgwụ kwa ụbọchị, n’ihe banyere ọnọdụ mberede, ịnwere ike ịmalite ọgwụgwọ insulin. Ndị ọrịa dị otú a kwesịrị ịga n'ihu na-a doseụ ọgwụ mbụ nke glimepiride ma n'otu oge ahụ malite iji obere insulin insulin, nke na-eji nwayọọ nwayọọ na-abawanye, n'otu n'otu, ọkwa nke ụgwọ metabolic. Ekwesịrị ịmalite ọgwụgwọ dị otú ahụ n'okpuru nlekọta nke dọkịta.

Dodoụbiga ya ókè

• Enweghi ike n’etiti mmega ahu na oriri ndi ahu,
• Ime mkpesa ma ọ bụ (karịchaa agadi) ezughị ezu nke onye ọrịa ịga kpọtụrụ dọkịta.
• Ọkpụkpụ akụrụ
• Alcoholụ mmanya na-egbu egbu, karịsịa na nri nri,
• Ọrịa imeju siri ike,
• Changesfọdụ mgbanwe ọrịa na usoro endocrine na-emetụta metabolism metabolism (dịka ọmụmaatụ, adenohypophysial ma ọ bụ adrenocortical insufficiency, nsị thyroid),
• Oge ejikọtara ọgwụ ndị ọzọ (lee mpaghara “ractionmekọrịta ọgwụ ndị ọzọ yana ụdị mmekọrịta ndị ọzọ”).

Ọ bụrụ na ihe ndị a dị n'elu na akụkụ nke hypoglycemia dị, ị kwesịrị ịgwa dọkịta gị ozugbo, dịka na nke a, a chọrọ nlezianya nyochaa ndị ọrịa. A ga - agbanwe doses ma ọ bụrụ na ụzọ ndụ onye ọrịa ahụ agbanwee ma ọ bụ ọrịa na - efe efe. Ọrịa hypoglycemia, nke na-egosipụta adrenergic counterregulation, nwere ike belata ma ọ bụ na-anọghị ya kpamkpam n'ọnọdụ mgbe hypoglycemia na-eji nwayọọ nwayọọ na ndị ọrịa nwere ọrịa autonomic neuropathy, ndị ọrịa agadi. Enwere ike belata oria n’aria ndị ọrịa n’otu n’otu na-eji b-adrenergic blockers nwere reserpine, clonidine, guanethidine, ma ọ bụ n’ụzọ ndị ọzọ. Hypoglycemia, n'ihe fọrọ nke nta ka ọ bụrụ n'ọnọdụ niile, enwere ike ịkwụsị ngwa ngwa site na oriri a na-enweta na carbohydrates ozugbo, dị ka shuga ma ọ bụ glucose (dịka ọmụmaatụ, n'ụdị mpempe shuga nke nwere ihe ọ fruitụ juiceụ mkpụrụ osisi shuga ma ọ bụ tii). Ya mere, onye ọrịa ahụ kwesịrị iburu gram glucose dịkarịa ala 20. Ihe ndị na-atọ ụtọ ụtọ mmadụ anaghị arụ ọrụ n'imeso hypoglycemia. Site na ahụmịhe iji ọgwụ ọgwụ sulfanylurea ndị ọzọ, a maara na, n'agbanyeghị agamnihu mbụ nke usoro ọgwụgwọ ewere, nlọghachi hypoglycemia ga-ekwe omume. Iji nlezianya na-achọpụta ọnọdụ onye ọrịa ahụ dị mkpa. Ọrịa hypoglycemia siri ike na-achọ ọgwụgwọ ozugbo n'okpuru nlekọta nke dọkịta, na n'ọnọdụ ndị siri ike, ụlọ ọgwụ nke onye ọrịa.

Mmetụta ọghọm:

Ọrịa hypoglycemia: ọgbụgbọ, ọgbụgbọ, isi ọwụwa, vomiting, nsogbu ụra, agụụ "agụụ, agụụ, ụra, adịghị mma nke ntị, nchekasị, ọgba aghara, mwepu okwu, iwe na iwe. Na mgbakwunye, mmeghachi omume adrenergic nwere ike ịdapụta: tachycardia, ọbara mgbali akwara, palpitations, sweating, nchegbu, obi arrhythmias na angina ọgụ. Aphasia, shoor, paresis, mmetụta uche na-adịghị ala ala, enweghị enyemaka, enweghị njide onwe onye, ​​enweghị nchekasị, ura na ọnwụ nke mmụọ ruo mgbe enwere mmụọ, iku ume na-enweghị ume na bradycardia.

Foto onyonyo a na-ahụ maka mwakpo hypoglycemia nwere ike ịdị ka ọnya afọ. Mgbe emechara ọnọdụ glycemic, ọrịa niile ndị a na-apụ n'anya.

• Akụkụ ụbụrụ: n’oge ọgwụgwọ (ọkachasị n’oge nke izizi), enwere ike ịhụ anya n’enweghi nsogbu, n’ihi mgbanwe nke ọkwa glucose ọbara.
• Ọkpụkpụ akwara: mmeghachi omume eriri afọ, dịka mgbu afọ na afọ ọsịsa, ọgbụgbọ, ọgbụgbọ, mmetụta nke nrụgide ma ọ bụ ejupụta na epigastrium, n'ọnọdụ ndị na - adịghị adị, enwere mmụba na enzymes imeju na nsị nsị (jaundice na cholestasis), ịba ọcha n'anya, nke nwere ike ibute gị imeju imeju.
• Sistem: Ọbara nwere ike ibute. N'ọnọdụ ndị na-adịghị ahụkebe, thrombocytopenia na, n'ọnọdụ ndị pụrụ iche, granulocytopenia, hemolytic anaemia, leukopenia, erythrocytopenia, agranulocytosis na pancytopenia (n'ihi myelosuppression) ga-ekwe omume.
• Nsonaazụ ndị ọzọ Ọrịa Allergic ma ọ bụ mmeghachi ahụ na-egbu ahụ n'ụdị urticaria, ihe ọkụ ma ọ bụ itching nwere ike ime mgbe ụfọdụ. Ọ bụrụ na hives mere, gakwuru dọkịta ozugbo.

Mmeghachi omume ndị a, dị ka iwu, adịghị agafe agafe, mana enwere ike ịga n’ihu, dyspnea na mbelata ọbara mgbali elu ruo ujo. N'ọnọdụ ndị dịpụrụ adịpụ, enwere ike nwetakwu mmetụta anụ ahụ maka ọrụ ọkụ, vasculitis nfụkasị yana mbelata nke ọkwa sodium n'ọbara ọbara.

Mmekọrịta na ọgwụ ndị ọzọ na mmanya:

Ojiji ọgwụ Amix ya na ụfọdụ usoro ọgwụgwọ ọgwụ ndị ọzọ nwere ike ibute mmụba na-adịghị mma ma ọ bụ mee ka ike gwụ hypoglycemic mmetụta nke ihe ahụ na-arụ ọrụ. Ekwesịrị ị drugsụ ọgwụ ndị ọzọ naanị mgbe ịgachara dọkịta (ma ọ bụ dịka o nyere aka).

Ekwesịrị ịtụle nke a mgbe ị na-ewere glimepiride na ndị na-egbochi CYP2C9 (dịka ọmụmaatụ fluconazole) ma ọ bụ ndị inducers CYP2C9 (dịka. Rifampicin).

Ahụmịhe nke ọgwụgwọ glimepiride ma ọ bụ ihe ndị ọzọ na - eme ka sulfonylurea na - egosi na enwere ụdị mmekọrịta a: ike nke mmetụta belata ogo glucose ọbara. N'ọnọdụ ụfọdụ, nke a na-eduga na hypoglycemia mgbe ị na-ewere otu n'ime ọgwụ ndị a: phenylbutazone, azapropazone na oxyphenbutazone, insulin na ọgwụ antidiabetic, metformin, salicylates nke tara-amino salicylic acid, anabolic steroids na nwoke mmekọahụ homonụ, chloramphenicolinolololin, chinewsolin fibrates, ACE inhibitors, fluoxetine, allopurinol, ọmịiko, cyclo-, tri-taifosfamidiv, sulfinpyrazone.

Mbelata na ịdị mma nke ọgwụ (mbelata mmetụta nke iwetulata ọkwa glucose ọbara dị ala) ma ọ bụ mmụba nke glucose ọbara na-apụta site na oge nchịkwa nke Amix na ọgwụ ndị na-esonụ: estrogen na progestogen, saluretics na ọgwụ thiazide, ọgwụ na-akpali akpali, glucocorticoids, phenothiazineeri, chlorpromazine, chlorpromazine, chlorpromazine, chlorpromazine, chlorpromazine, chlorpromazine, chlorpromazine, chlorpromazine, chlorpromazine, chlorpromazine] , acid nicotinic (na nnukwu doses) na nicotinic acid derivatives, laxatives (ogologo oge), phenytoin, diazoxide, glucagon, barbiturates, rifampicin, aceto amide.

Ojiji nke antagonists nke H2-receiptors, b-blockers, clonidine na reserpine nwere ike iduga na -eme ihe ma obu mee ka mbelata ọbara glucose kpatara site n’inwe Amiksu. Sympatolytics dị ka b-blockers, clonidine, gaunetidine na reserpine nwere ike kpuchie ma ọ bụ kpochapụ ihe mgbaàmà nke ọrịa adrenergic, na-eduga na hypoglycemia. Comụbiga mmanya ókè nwere ike ịbawanye ma ọ bụ mee ka ike gwụ hypoglycemic mmetụta nke glimepiride n'ụzọ enweghị atụ. Glimepiride nwere ike ịkwalite ma ọ bụ wedaa nsonaazụ nke usoro coumarin.

Ngwakọta na akụrụngwa:

Ngwakọta: Otu mbadamba 1 nwere glimepiride 1.2, 3 ma ọ bụ 4 mg.

Mwepụta weputara: Mpempe akwụkwọ 1 mg Nke 10x3, Nke 10x9, Nke 10x12.

Glimepiride bụ ihe dị n'ọgwụ ahụ, ọgwụ sitere na sulfonylurea. A na-eji ọnụ, nwere hypoglycemic edinam. Ọ na - akpali mmepụta nke insulin site na mkpụrụ ndụ beta nke pancreas, na - eme ka nkwupụta anụ ahụ dị na insulin, na - eme ka ntọhapụ insulin Mgbe nchịkwa ọnụ gachara, nnabata glimepiride bụ 100%. Nri adighi emetuta bioavailability, kama ọ na --ebelata ntakịrị nzere. Cmax (mkpokọta kachasị na ọbara ọbara) erutela awa 2.5 mgbe nchịkwa ọnụ (nkezi ke serum ọbara bụ 0.3 μg / ml mgbe ị na-ewere ọtụtụ ọgwụ 4 mg kwa ụbọchị). Enwere mmekọrịta kwụ ọtọ n’etiti dose na Cmax, yana n’etiti dose na AUC (mpaghara ahụ n’okpuru oge nlebara anya).

Nkesa nke glimepiride bu akara ntinye nke di ala (ihe ruru lita 8.8), nke ra ka olu nkenke maka albumin, nkenke di ala (dika ihe dika 48 ml / min.), Oke nkwekorita nke inye protein plasma (>> 99%). Biotransformation na mkpochapu: ọkara plasma ọkara ndụ maka glimepiride bụ awa ise ruo asatọ. Uru a bara uru maka ikpebi ebe a na-etinye ọtụtụ ihe mgbe ọ bụla. Mgbe ị sesụsịrị nnukwu ọgwụ, obere mmụba na plasma ọkara nke glimepiride kwuru.

Ọnọdụ nchekwa: chekwaa na okpomọkụ ruo 30 Celsius C. Zere ụmụaka.

Mpempe mwepụta

• Amix 1: Mbadamba nkume oval pink nwere eriri nkewa na akuku ya.
• Amix 2: oval greenish mbido nwere eriri nkewa na akụkụ abụọ.
• Amix 3: oval mbadamba odo edo edo nwere eriri nkewa na akuku.
• Amix 4: Mbadamba mbadamba nkume na-acha anụnụ anụnụ nwere akara nwere akụkụ abụọ.

10 mbadamba ụrọ na bred - pensụ atọ, nke itolu ma ọ bụ iri na abụọ na igbe katọn.

Pharmacodynamics na pharmacokinetics

Mlọ ọgwụ

Glimepiride Ọ bụ ya onye nnọchi anya hypoglycemic maka nchịkwa ọnụ (usoro sitere na ya sulfonylureas) Họrọ nhọrọ insulin mkpụrụ ndụ pancreatic B, na - eme ka ntọhapụ dịkwuo elu insulinna - eme ka ahụ mmadụ nwee mmetụta nke anụ ahụ insulin.

Mlọ ọgwụ

Mgbe iwere bioavailability glimepiridena-erute 100%. Nri anaghị emetụta ogo mmịcha, mana ọ bụ naanị ntakịrị ka ọ na-egbochi ya. Oke kasịnụ ke ọbara (edoziri 2-3 awa mgbe ịbanye.)

Ogo nke jikọtara na protein plasma karịrị 99%. Ọkara ọkara bụ awa 6-8. Metabolized kpamkpam. N'ime ya ka ọ dị na mmamịrị na eriri afọ.

Ihe ngbanwe

Ọrịa shuga mellitusụdị nke mbụ mamịrị coma, mamịrị ketoacidosis, tụụrụ ime ma obu lactation. Ọzọkwa, a gaghị akwado ọgwụ ahụ maka ndị ọrịa nwere uche ihe mejuputara ogwu ahu, ihe ndia sulfonylureas ma ọ bụ ndị ọzọ ọgwụ sulfa.

Nsonaazụ

Mmepe enwere ike nke mgbaàmà ndị a hypoglycemia: "Wolf" agụụọgbụgbọ enweghị mmasịvomiting iro ụra, isi ọwụwa, nchekasị, oke iwe,nsogbu ụra, ịta ahụhụ na-ebelata, mmeghachi omume na-ebelata, ọgba aghara, ịda mbankwarụ okwu, nrụrụ anya, aphasia, shooruche mebiri, paresisanya ntughari delirium, cramps Centralọnwụ nke mmụọ bradycardia. Ọ ga-ekwe omume adrenergicmmeghachi omume: echiche nke nchegbu, ọsụsọ, ọbara mgbali ikeọdịdọ angina pectoris, tachycardia, arrhythmia.

Site na nke echiche: nkwarụ anya nke nwa oge.

Site na mgbaze: mgbu afọ, ọgbụgbọ, ọgbụgbọ, mmetụta nke jupụta na epigastrium, afọ ọsịsaMgbanwe na enzymu nke imeju, ịba ọcha n'anya.

Site na hematopoiesis: leukopenia, agranulocytosis, thrombocytopenia, hemolytic anaemia, granulocytopenia, erythrocytopenia, pancytopenia.

Mmeghachi omume ọjọọ ndị ọzọ: itching, urticaria, dyspneambelata mgbali mgbali.

N'ọnọdụ ndị a na - adịghị ahụkebe, ihe ndị a na - ekwupụtakwa: nsonaazụ, vasculitis nfụkasịmbelata larịị sodium n’ime ọbara.

Ntụziaka maka ojiji (Usoro na usoro onunu ogwu)

Ọnọdụ ndị bụ isi maka ọgwụgwọ na-aga nke ọma: nri, imega ahụ mgbe niile na ilele ọbara na mmamịrị mgbe niile. Site na nsonaazụ nke nyocha a na-ekpebi usoro ị drugụ ọgwụ ahụ.

Ọgwụ nke mbụ bụ 1 mg glimepiride kwa ụbọchị. A na-eji otu usoro ahụ emere ọgwụgwọ nkwado mgbe ị na-enweta njikwa na ọnọdụ onye ọrịa.

Ọ bụrụ na enweghị ike ijikwa ọnọdụ onye ọrịa ahụ ka ọ gaghị enweta, usoro ịba ụba ahụ na-abawanye 1, 3 ma ọ bụ 2 mg glimepiridekwa ụbọchị, otu ugboro ka izu abụọ.

N'ikukuglimepiride karịrị 4 mg kwa ụbọchị na-eme ka ọ dịkwuo mma naanị n'ọnọdụ pụrụ iche. Oke kachasị bụ 6 mg nke ọgwụ kwa ụbọchị.

N'ime ndị ọrịa na-akwụghị ụgwọ maka metabolism na-akpata ike ọgwụgwụ, ọbụlagodi mgbe ha riri oke doses, ọgwụgwọ nwere ike ịmalite insulin naanị ma ọ bụrụ na ọ dị oke mkpa. Ndị ọrịa dị otú a kwesịrị ịnọgide na-eji ọgwụ mbụ ahụ ma n'otu oge ahụ malite iji obere insulin insulin, n'ọdịnihu, a na-ahapụ ha ka ha jiri nwayọọ nwayọọ mụbaa dabere na ọkwa nke ụgwọ nkwụghachi metabolic.

Dosekè nkesa kwa ụbọchị

Otutu oge zuru oke maka ahụ ya takeụrụ otu ọgwụ kwa ụbọchị tupu ma ọ bụ n'oge nri ụtụtụ. Ọ bụrụ na onye ọrịa echefula ị theụ ọgwụ ọzọ, mgbe ahụ, usoro nke na-esote ya adịghị mkpa ka abawanye.

Nghazi udiri ọgwụ na-esote

N'oge ọgwụgwọ, mmụba nke uche insulin na belata mkpa glimepiride. Ya mere, igbochi hypoglycemia kwesịrị ị belata oke onunu ogwu ma ọ bụ kwụsị ọgwụ. Site na mmụba ma ọ bụ iwetulata ịdị arọ, mgbanwe ndụ ya ma ọ bụ ọdịdị nke ihe ndị ọzọ na-eme ka ọghọm ya dị elu hypoglycemia ma obu hyperglycemia, ọ dị mkpa ịtụle usoro onunu ogwu nke ogwu.

Ntughari site na ihe ndi ozo ekwuputara hypoglycemic na ojiji nke Amix

N'ọnọdụ a, ekwesịrị ịtụle ogo mmetụta ọgwụ na ahụ na ọkara ndụ oge. Na aga eji ogologo ndị ọrụ antidiabetic site na ndụ ogologo ọkara, a na-atụ aro ịmalite ọgwụ Amix mgbe ọ gwụsịrị oge kpochapụrụ, ebe ọ bụ na enwere mmetụ mgbakwunye ga-ekwe omume.

Na-agbanwe site na insulin ka amix

N'ọnọdụ ndị pụrụ iche, mgbe a na-ahazi ọnọdụ nke ndị ọrịa nwere ụdị shuga 2 insulin, ngosipụta nwere ike ịpụta ka ịgbanwee gaa glimepiride. Mgbanwe a na Amix n’ime ndị ọrịa a kwesịrị ka emee ya n’okpuru nlekọta nke dibịa.

Dodoụbiga ya ókè

Mgbe ịdoụbiga ọgwụ ókè hypoglycemia, nke nwere ike ịdịru awa iri na abụọ rue ụbọchị atọ. A na-atụ aro ịga ụlọ ọgwụ n'ozuzu ụlọ ọgwụ.Symptomsụbiga ihe ọ symptomsụ symptomsụ nwere ike ịgụnye ọgbụgbọ ma ọ bụ ọgbụgbọ, mgbu afọ, oke iwe, ọhụhụ. ịma jijiji ndagwurugwu, ura, ehighi ura, Comana ogwe.

Do therapyụbiga ọgwụ ike ókè mejupụtara lavage gastric, mmiri ọ drinkingụ ,ụ, carbon na-arụ ọrụ na sodium sulfate. Ọzọkwa, n'oge ọ bụla o kwere omume, ịkwesịrị ịmalite iji glucose. Usoro ọgwụgwọ ọzọ kwesịrị ịbụ Symptomatic.

Mmekorita

Mgbe ejikọtara ya na Phenylbutazone, Azapropazone, Metformin, Oxyphenbutazone, insulin, ọgwụ antidiabetic, salicylates, anabolic steroid, androgens, coumarin-ụdị anticoagulants, chloramphenicol, Fenfluramine, fibratins, Acidumoliponofilinfinfinfinfinfinhypoglycemia nwere ike ịmalite.

Ka ị na-eji estrogens, saluretics, progestogens, thiazide diuretics, glucocorticoids, ọgwụ na-akpali akpali, ihe ndị na-akpali phenothiazine (Adrenaline, Chlorpromazine), sympathomimetics, nicotinic acid na ntinye ya, uzo nri, Phenytoin, Glucagon, Diazoxide, Rifampicin, Barbiturates, Acetosolamidemmebi nke mmetụta nke ọgwụ na mmụba nke glucose ọbara n'ọbara ga-ekwe omume.

Glimepiridemgbanwe mmetụta coumarin-like ọgwụ.

Ntụziaka pụrụ iche

Na nmalite ọgwụgwọ, onye ọrịa nwere ike ịbawanye ihe ọghọm nke hypoglycemia- Nke a chọrọ nlezianya nyochaa ọnọdụ ya. Ihe ndị na - eme ka mgbanye glucose plasma dị ala gụnyere: nri na-adịghị edozi ahụ, njehie nri, erighị ihe na-edozi ahụ, nri na-adịghị mma, na nri iri.

Amipyrid, Amaril, Glayri, Glemaz, Glianov, Glimaks, Glinova, Glyrid, Dimaril, Diapirid, Altar, Perinel, Elgim.

Enweghị ahụmịhe banyere iji ọgwụ eme ihe na ụmụaka.

N'oge ime na lactation

Aremụ nwanyị dị ime nke buru ụzọ ọgwụ ahụ agafere na ọgwụgwọ insulin.

Ọ bụrụ na onye ọrịa ahụ kwesịrị iwere insulin, a na-adụ ya ọdụ ka ọ kwụsị ịsa ahụ.

Ahụmịhe nke iji ọgwụ ahụ ezughi iji gosipụta ezigbo ebumnuche banyere ịdị irè ya. N'oge a, a na-ejikarị ọgwụ analogues nke ọgwụ a. Ego sitere na ego glimepiride bụ ọgwụ ịhọrọ oria shuga seconddị nke abụọ ma nyere aka wepu ojiji insulin insulin. Mgbe ejiri ya na usoro ọgwụgwọ akwadoro, mmetụta ndị dị obere anaghị adịkarị.

AMIX vet HTTs (AMIX vet STS)

Aha ahia ahia nke ọgwụ: AMIX ™ Vet CTZ 150 mg / g (AMIX ™ Vet STS 150 mg / g).

Aha mba ụwa na-akwadoghị: chlortetracycline.
Sdị usoro ọgwụgwọ: ntụ ntụ maka nchịkwa ọnụ.
AMIX ™ Vet XTC 150 mg / g nwere na 1 g dị ka ihe na - arụ ọrụ: chlortetracycline - 150 mg (dị ka chlortetracycline hydrochloride), dị ka ihe inyeaka: ngwaahịa gbaa ụka nke Streptomyces aureofaciens na ntụ ọka wit ruo 1 g.
N’ile anya, AMIX ™ Vet XTC 150 mg / g bụ ntụ sitere n’ọkụ aja aja rue aja aja gbara ọchịchịrị.
AMIX ™ Vet XTC 150 mg / g dị na akpa mkpịsị ugodi okpukpu atọ nwere polyethylene ma ọ bụ akpa akwụkwọ oyi akwa.
A na-echekwa AMIX ™ Vet XTC 150 mg / g na nkwakọ ngwaahịa onye nrụpụta, dị iche na nri na nri, na ebe kpọrọ nkụ, na ọkwa dị 2 Celsius ruo 25 Celsius.
Ekwesịrị ịchekwa AMIX ™ Vet XTC 150 mg / g ebe ụmụaka agaghị eru.
A na-ewepụ ọgwụ na-adịghị eji eme ihe dịka iwu chọrọ.

Ngwá ọgwụ ọgwụ:

AMIX ™ Vet CTZ 150 mg / g bụ ọgwụ nje na-egbu nje nke otu tetracycline.
Chlortertracycline, nke bụ akụkụ nke ọgwụ ahụ nwere ọgwụ dị iche iche nke antibacterial, na-arụ ọrụ megide micromganic gram-gram-gram, nke gụnyere Escherichia coli, Klebsiella pneumoniae, Proteus spp., Salmonella spp., Staphylococcus spp. Pasteurella multocida, Streptococci ma e wezụga, Rickettsia spp., Chlamydia, Protozoa na Mycoplasma spp.
Ofzọ mmetụta nke nje bactericstatic nke mgbochi bụ iji gbochie njikọ nke protein na-egbochi nje na sel microbial na ọkwa ribosomal, nke na-egbochi nkewa na nguzobe mgbidi sel.
Chlortetracycline anaghị etinye obi gị dum na eriri afọ. Ogo ogo mmụba na-ebelata n'ihu sọlfọ nke sọks abụọ na nke sọks nke tetracyclines na –emepụta ogige dị iche iche. Chlortetracycline na-ejikọ nke ọma na protein plasma ma na-ekesa ya n'ime ahụ niile, na-eru n'ọtụtụ kachasị na umeji, akwara, ngụgụ na mpaghara ndị na-arụ ọrụ nke ịmepụta ọkpụkpụ. Oke ntụpọ tetracycline n'ime ọbara bụ erute 4 awa mgbe nchịkwa gasịrị. Ọgwụgwọ ọgwụgwọ na-adịgide ruo awa 12-18. Tetracycline fọrọ nke nta ka ọ banye na mmiri nke akwara azụ, mana ọkwa ya nwere ike ịbawanye elu site na mbufụt nke meninges. Ọkara ọkara nke chlortetracycline bụ 8,8 awa. A ga - apịpụ ya karia mmamịrị na ọnya. Fekwara anụ ahụ nwere ike wepụta ihe ruru pacenti iri nke tetracycline na mmiri.

Usoro Ngwa:

AMIX ™ Vet XTC 150 mg / g ka enyere ya maka ezì, ụmụ atụrụ, ụmụ ehi maka ọgwụgwọ, anụ ọkụkọ maka ahụike na ọgwụgwọ na-arịa ọrịa na-arịa ọrịa okuku ume, sistem mkpụrụ ndụ, akwara afọ na ọrịa nje ndị ọzọ na nke na nke abụọ. ọdịnala nke ndị na - akpata ihe na - eme ka chlortetracycline nwee mmetụta.
AMIX ™ Vet XTC 150 mg / g amachibidoro maka ndị na-ahụ maka mkpụrụ akụ nwere nnukwu mgbaze mkpụrụ ndụ, na-edebe hens, yana ụmụ anụmanụ nwere nnukwu akụrụ na enweghi oke ịba ọcha n'anya.
Itinye nri na usoro otu ma ọ bụ otu ugboro kwa ụbọchị maka 5-10 ụbọchị.

Ọzụzụ otu:
Iji tinye 3.0 - 4.0 n'arọ nke ọgwụ kwa ton nke ngwakọta nri (nke kwekọrọ na 450-600 g nke chlortetracycline kwa ton nke nri ma ọ bụ 20-30 mg / n'arọ nke oke ahụ).
Individualbọchị ọ bụla ị areụ ọgwụ ahụ na-egosi na tebụl:

Mgbochi:
Tinye 1.5-2.0 n'arọ nke ọgwụ kwa ton nke ngwakọta nri (nke kwekọrọ na 225-300 g nke chlortetracycline / ton nke ndepụta ma ọ bụ 10-15 mg / n'arọ nke ịdị ahụ).

Dodoụbiga ya ókè

Achọpụtaghị mgbaama nke ị anụbiga mmanya ókè.

Atụmatụ:

Edebeghi nkọwapụta nke ọgwụ ahụ n'oge ojiji mbụ ya na oge ọ kwụsịrị.
Izere ọgwụ ọzọ na ọgwụ a ga-ezere, ebe nke a nwere ike ibute mbelata arụmọrụ ọgwụgwọ. Ọ bụrụ na egopụtaghị oge iji ọgwụ ahụ ugboro ugboro, ekwesịrị iji ya ngwa ngwa o kwere omume, n'otu usoro yana otu atụmatụ ahụ.
Achọpụtabeghị nsonaazụ ndị ọzọ, ewezuga okwu gbasara ịensụ ọgwụ mmadụ n'otu n'otu. Site na mmụba nke ụmụ anụmanụ na-abawanye na chlortetracycline yana ọdịdị ya
nke mmeghachi omume nfụkasị ahụ, a na-eji AMIKSTM ve XTC 150 mg / g akwụsị ma na-eme ka usoro ọgwụgwọ kwụsịlata.
Ejila AMIX ™ Vet XTC 150 mg / g na njikọta ọgwụ nje (penisiliniins, cephalosporins, wdg), kalsylorlor, calcium gluconate, ammonium chloride, antacids, kaolin, nkwadebe nwere iron, magnesium, calcium na aluminom, anya. enwere ike ibelata na ọrụ nje ihe ya.
Anabataghị igbu ehi na ụmụ atụrụ maka anụ tupu ụbọchị iri na abụọ, ezì na anụ ọkụkọ - ụbọchị iri mgbe ị theụ ọgwụ ọjọọ ikpeazụ. Anụ nke anụmanụ a ga-egbu tupu ngafe nke oge ahụ ka enwere ike iji ya nye anụmanụ aji.

Mgbochi onwe

Mgbe ị na-eji ọgwụ AMIX ™ Vet XTC 150 mg / g, na-eduzi usoro ọgwụgwọ na mgbochi, a ga-ahụrịrị usoro iwu nke ịdị ọcha onwe onye yana nchekwa nchekwa mgbe ejiri ọgwụ ọjọọ rụọ ọrụ.
Mgbe ị rụchara ọrụ, jiri mmiri ọkụ na ncha sachaa aka gị.
A na-atụ aro ọrụ niile na AMIX ™ Vet XTC 150 mg / g site na iji ihe nchebe onwe gị (akwa mmiri, isi mmiri, uwe mpe mpe akwa, iko nchekwa, iku ume ma ọ bụ nkpuchi ihu). Ka ị na-arụ ọrụ ọgwụ ahụ, a machibidoro ị drinkụ mmanya, ị smokeụ sịga na iri nri. Mgbe ị gachara ọrụ, ị ga-eji ncha na mmiri sachaa ihu gị na aka gị, hichaa ọnụ gị.
Ọ bụrụ na akpụkpọ ahụ ma ọ bụ akpụkpọ anụ mucous na kọntaktị na mberede, jiri mmiri pọpụ mmiri wee hichaa ya; ọ bụrụ na ọ banye gị n'anya, were mmiri saa ozugbo wee gakwuru dọkịta ma ọ bụrụ na ọ dị mkpa.

Ndụ shelf na nchekwa:

Ndụ nchekwa nke ọgwụ n'okpuru ọnọdụ nchekwa na ngwugwu a kara akara bụ afọ abụọ site na ụbọchị emepụtara, mgbe emepechara ngwugwu - enweghị ihe karịrị ụbọchị 28, na ntanetị - ihe karịrị ụbọchị 3.

Ejila ọgwụ ahụ mgbe ọ gwụchara.
A na-echekwa AMIX ™ Vet XTC 150 mg / g na nkwakọ ngwaahịa onye nrụpụta, dị iche na nri na nri, na ebe kpọrọ nkụ, na ọkwa dị 2 Celsius ruo 25 Celsius.
Ekwesịrị ịchekwa AMIX ™ Vet XTC 150 mg / g ebe ụmụaka agaghị eru.
A na-ewepụ ọgwụ na-adịghị eji eme ihe dịka iwu chọrọ.

Enwere ike ịchọta ndepụta niile na ntuziaka nke ngwaahịa anụ ụlọ na katalọgụ ngwaahịa anyị na weebụsaịtị anyị. Banyere ọnụahịa ahụ, yana ohere ịzụrụ, ị ga-enwe obi ụtọ ịgwa ndị na-ahụ maka ọrụ anyị.

Nkpuru ihe Amix

• Otu mbadamba ọgwụ Amix 1 nwere 1 mg glimepiride.
• Otu mbadamba ọgwụ Amix 2 nwere 2 mg glimepiride.
• Otu mbadamba ọgwụ Amix 3 nwere 3 mg glimepiride.
• Otu mbadamba ọgwụ Amix 4 nwere 4 mgglimepiride.

Ihe ndi ozo: povidone 25, lactose, polysorbate 80, microcrystalline cellulose, crospovidone, silicon dioxide, magnesium stearate, iron oxide, dai.

Amix - Ntuziaka maka iji ya

Ọnọdụ ndị bụ isi maka ọgwụgwọ na-aga nke ọma: nri, imega ahụ mgbe niile na ilele ọbara na mmamịrị mgbe niile. Site na nsonaazụ nke nyocha a na-ekpebi usoro ị drugụ ọgwụ ahụ.

Usoro mbụ nke ọgwụ ahụ bụ 1 mg nke glimepiride kwa ụbọchị. A na-eji otu usoro ahụ emere ọgwụgwọ nkwado mgbe ị na-enweta njikwa na ọnọdụ onye ọrịa.

Ọ bụrụ na enweghị ike ijikwa ọnọdụ onye ọrịa ahụ achọrọ, usoro ịba ụba ga-abawanye site na 1, 3 ma ọ bụ 2 mg nke glimepiride kwa ụbọchị ruo izu abụọ.

Gnweta glimepiride karịa 4 mg kwa ụbọchị na-enye mmụba naanị n'ọnọdụ ndị pụrụ iche. Oke kachasị bụ 6 mg nke ọgwụ kwa ụbọchị.

N'ime ndị ọrịa na-akwụghị ụgwọ maka metabolism na-akpata ahụ ike, ọbụlagodi mgbe ha riri oke ogwu, ọgwụgwọ insulin nwere ike ịmalite ma ọ bụrụ na ọ dị oke mkpa. Ndị ọrịa dị otú a kwesịrị ịnọgide na-eji ọgwụ mbụ ahụ ma n'otu oge ahụ malite iji obere insulin insulin, n'ọdịnihu, a na-ahapụ ha ka ha jiri nwayọọ nwayọọ mụbaa dabere na ọkwa nke ụgwọ nkwụghachi metabolic.

Dosekè nkesa kwa ụbọchị

Otutu oge zuru oke maka ahụ ya takeụrụ otu ọgwụ kwa ụbọchị tupu ma ọ bụ n'oge nri ụtụtụ. Ọ bụrụ na onye ọrịa echefula ị theụ ọgwụ ọzọ, mgbe ahụ, usoro nke na-esote ya adịghị mkpa ka abawanye.

Nghazi udiri ọgwụ na-esote

N'oge ọgwụgwọ, mmụba nke mmetụta insulin na mbelata mkpa nke glimepiride ga-ekwe omume. Ya mere, iji gbochie hypoglycemia, ekwesịrị ị belata oke onunu ogwu ma ọ bụ kwụsị ọgwụ ahụ. Site na mmụba ma ọ bụ ibelata ibu, mgbanwe ndụ, ma ọ bụ ihe ndị ọzọ na-abawanye oke nke hypoglycemia ma ọ bụ hyperglycemia, ọ dị mkpa ịtụleghachi usoro onunu ogwu nke ogwu.

Ntughari site na ihe ndi ozo ekwuputara hypoglycemic na ojiji nke Amix

N'ọnọdụ a, ekwesịrị ịtụle ogo mmetụta ọgwụ na ahụ na ọkara ndụ oge. Site na iji ojiji ndị na-egbu egbu ogologo oge iji mee ogologo ndụ, ọ na-atụ aro ịmalite usoro Amix mgbe ọ gwụsịrị oge ikpochapu ahụ, ebe enwere ike ịgbakwunye mmetụta mgbakwunye.

Na-agbanwe site na insulin ka amix

N'ọnọdụ ndị pụrụ iche, mgbe ọnọdụ insulin na-achịkwa ọnọdụ ndị ọrịa nwere ụdị shuga 2, ihe ngosi maka ịgbanye glimepiride nwere ike ime. Mgbanwe a na Amix n’ime ndị ọrịa a kwesịrị ka emee ya n’okpuru nlekọta nke dibịa.