Rosinsulin R, C na M - njiri mara na ntuziaka maka ojiji

Mlọ ọgwụ

Rinsulin P bụ insulin nke mmadụ nwetara site na iji teknụzụ DNA recombinant. Short insulin. Ọ na - emekọrịta otu onye na - anabata ihe n'ụsọ akpụkpọ ahụ cytoplasmic nke mkpụrụ ndụ ma mepụta insulin-receptor complex nke na - akpali usoro intracellular, gụnyere njikọ nke ọtụtụ enzymes isi (hexokinase, pyruvate kinase, glycogen synthase, wdg). A na-eme ka mbelata ọbara glucose ọbara site na mmụba na njem nke intracellular ya, mmụba dị ukwuu na njigide anụ ahụ, mkpali nke lipogenesis, glycogenogenesis, mbelata ọnụego glucose sitere na imeju, wdg.
Ogologo oge nke ihe insulin na-eme bu n'ihi nzere nke mmiri, nke dabere na otutu ihe (dika ima atu, uzo ya na ebe ochichi ya), ya mere profaịlụ nke insulin n’ariri mgbanwe di omimi, ma n’ebe ndi mmadu di iche na otu mmadu. Na nkezi, mgbe nchịkwa subcutaneous gasịrị, Rinsulin P malitere ime ihe mgbe nkeji 30 gasịrị, oke kachasị na-etolite n'agbata awa 1 na awa, oge ọrụ ahụ bụ awa 8.

Mlọ ọgwụ
Njuputa nke nnabata na mmalite nke mmetụta nke insulin na-adabere n'ụzọ nke nchịkwa (subcutaneously, intramuscularly, intravenously), ebe nchịkwa (afọ, apata ụkwụ, isi), dose (olu insulin insulin), ịta insulin na ọgwụ, wdg Ọ na-ekesa na-ezighi ezi gafee akwara ndị ahụ ma ghara ịbanye na ya. ihe mgbochi placental na n’ime mmiri ara. Ọ bụ insulinase na-abụkarị imeju ya na akụrụ. Iwepu ọkara ndụ na-eme ọtụtụ nkeji. Ọ bụ ya bụ akụrụ (30-80%).

Ihe ngosi maka ojiji

• Ọrịa shuga 1dị 1
• 2dị nke abụọ nke ọrịa shuga mellitus: ogbo nke iguzogide ndị ọrịa hypoglycemic nke ọnụ, nguzogide elele ọgwụ ndị a (n'oge ọgwụgwọ njikọta), ọrịa na-efe efe.
• Diabetesdị shuga nke afọ abụọ n’ime ụmụ nwanyị dị ime
• Ọnọdụ ọnọdụ mberede na ndị ọrịa nwere ọrịa mellitus na-agbaso oke metabolism metabolism

Usoro onunu ogwu na nhazi

Usoro usoro onunu ogwu na uzo ochichi ya

Ezubere ọgwụ ahụ maka nchịkwa subcutaneous, intramuscular na intravenous.
Ọ bụ dọkịta ga-ekpebi ọ̀tụ̀tụ̀ na ụzọ e si elekọta ọgwụ ahụ n’otu n’ozi ọ bụla dabere n’ọbara glucose n’ọbara.
Na nkezi, kwa ụbọchị ọgwụ a sitere na 0,5 ruo 1 IU / kg body body (dabere na njirimara nke onye ọrịa na ịba ụba glucose ọbara).
A na-enye ọgwụ ahụ nkeji iri atọ tupu nri ma ọ bụ nri nwere carbohydrates.
Okpomoku nke mmanu insulin kwesiri ino na okpomoku. Site na monotherapy na ọgwụ, ugboro nchịkwa bụ ugboro 3 kwa ụbọchị (ọ bụrụ na ọ dị mkpa, ruo ugboro 5-6 kwa ụbọchị). N'ihe dị kwa ụbọchị karịrị 0.6 IU / n'arọ, a ga-enye ọgwụ ahụ n'ụdị ọgwụ were gbasaa 2 ma ọ bụ karịa na akụkụ dị iche iche nke ahụ. Ọgwụ a na-adọtakarị subcutaneously n'ime mgbidi akụkụ ihu. A pụkwara ime inje n'apata ụkwụ, mana n'oche ma ọ bụ ubu na ịkọwapụta akwara uru.
Okwesiri igbanwe ebe ogwu ngbanyere na mpaghara anatomical iji gbochie mmepe nke lipo-dystrophy. Site na nchịkwa insulin nke dị n'okpuru ala, a ga-akpachara anya ịghara ịbanye na arịa ọbara n'oge ntụtụ. Mgbe ogwu ogbugba gasịrị, ekwesighi ịhịa aka ntụtụ. Ekwesịrị ịzụ ndị ọrịa ka esi eji ngwaọrụ nnabata insulin ya mee ihe nke ọma.
Enwere ike ịnye ọgwụ ahụ ọgwụ naanị na nlekọta nke dibịa.
Enwere ike iji vials ma ọ bụrụ na ọdịnaya ha bụ mmiri doro anya na-enweghị ụcha na-enweghị irighiri ihe. Nweghị ike iji ọgwụ ahụ ma ọ bụrụ na eburu ụzọ gosipụta na ngwọta ahụ. Rinsulin ® P bụ insulin na-adị mkpụmkpụ ma a na-ejikarị ya na insulin na-arụ ọrụ na-arụ ọrụ (Rinsulin ® NPH).
O kwere omume ịchekwa ọgwụ eji eme ihe n'ụlọ okpomọkụ (site na 15 ruo 25 Celsius) maka ihe na-erughị ụbọchị 28.

Mmetụta akụkụ

N'ihi mmetụta nke metabolism metabolism: ọnọdụ hypoglycemic (pallor nke anụ ahụ, ịba ụba ọsụsọ, palpitations, tremors, akpata oyi, agụụ, nhụjuanya, paresthesia nke mucosa oral, adịghị ike, isi ọwụwa, ọgbụgbọ, belata acuity visual). Nnukwu hypoglycemia siri ike nwere ike iduga mmepe nke hypoglycemic coma.
Mmeghachi omume nfụkasị ahụ: akpukpo ahu, akpukpo nke Quincke, ujo anafilactic.
Mmeghachi omume mpaghara: hyperemia, ọsụsọ na itching na saịtị ịgba ahụ, yana iji ogologo oge - lipodystrophy na saịtị ịgba ntụtụ.
Ndị ọzọ: edema, ntakịrị oge na ntinye anya (ọ na - ebido na mmalite ọgwụgwọ).
Ọ bụrụ na onye ọrịa ahụ achọpụta mmepe nke hypoglycemia ma ọ bụ nwee omume nke nsụhọ, ọ kwesịrị ịgwa dọkịta ozugbo.
Ọ bụrụ na-egosipụta mmetụta ndị ọzọ ọ bụla akọwapụtaghị n’elu, onye ọrịa ahụ should kwesịrị ịkpọtụrụ dọkịta.

Ntụziaka pụrụ iche

Kpachara anya maka iji ya

Na-emegide usoro ịgwọ ọrịa insulin, ọ dị mkpa ileba anya mgbe niile itinye uche glucose ọbara.
Ihe kpatara hypoglycemia na mgbakwunye na insulin ịdoụbiga mmanya ókè nwere ike ịbụ: ị replacementụ ọgwụ, nzere nri, vomiting, afọ ọsịsa, mmụba anụ ahụ, ọrịa na-ebelata mkpa insulin (ọrụ imeju na akụrụ na-emebi emebi, hypofunction nke adrenal cortex, pituitary ma ọ bụ thyroid gland), mgbanwe nke nsị, yana iso ọgwụ ndị ọzọ na-emekọrịta ihe.
Singzọ ezighi ezi ma ọ bụ ihe mgbochi na nchịkwa insulin, karịsịa na ndị ọrịa nwere ọrịa shuga 1, nwere ike ibute hyperglycemia. Ọtụtụ mgbe, mgbaàmà mbụ nke hyperglycemia na-amalite nwayọọ nwayọọ karịa ọtụtụ awa ma ọ bụ ụbọchị. Ndị a gụnyere akpịrị ịkpọ nkụ, mmamịrị nke ukwuu, ọgbụgbọ, ọgbụgbọ, ọgbụgbọ, ọbara ọbara na ajị anụ, akpọnwụ akpịrị, enweghị agụụ, isi nke acetone na ikuku ikuku. Ọ bụrụ na agwọtaghị ya, hyperglycemia n'ụdị shuga 1 nwere ike ibute mmepe nke ọrịa ketoacidosis na-eyi ndụ egwu.
Ekwesịrị idozi ọnụọgụ insulin maka arụ ọrụ thyroid, ọrịa Addison, hypopituitarism, ọrụ imeju na akụrụ na-arịa ya na ọrịa shuga na ndị mmadụ karịa afọ 65.
Ọ dịkwa mkpa iji dozie insulin nke insulin ma ọ bụrụ na onye ọrịa ahụ na-eme ka mmega ahụ sie ike ma ọ bụ gbanwee ụdị nri a na-emebu.
Ọrịa concoitant, ọkachasị ọrịa na ọnọdụ ya na ahụ ọkụ na-eme ka ebulite insulin.
Ekwesịrị ịbufe onye ọrịa na ụdị insulin ọ bụla ma ọ bụ ịkwado insulin nke onye nrụpụta ọzọ ga-emerịrị n'okpuru nlekọta nke dibia.
N'ihi na enwere ike ịda mmiri na ụfọdụ catheters, a naghị atụ aro iji ọgwụ ahụ na nfuli insulin.

Mmetụta ikike ịkwọ ụgbọala na usoro

Na njikọ ebumnuche insulin, mgbanwe dị n'ụdị ya, ma ọ bụ ọnụnọ nrụgide anụ ahụ ma ọ bụ nke uche, ọ nwere ike imebi ikike ịkwọ ụgbọala ma ọ bụ usoro dịgasị iche iche, yana isonye n'ihe omume ndị ọzọ dị ize ndụ nke chọrọ nlebara anya na ọsọ nke mmeghachi omume.

Emeputa

Adreesị ebe emepụtara:

1. 142279, ógbè Moscow, ógbè Serpukhov, r.p. Obolensk, ụlọ 82, ikp.
2. 142279, Ógbè Moscow, ógbè Serpukhov, pos. Obolensk, ụlọ 83, udo. AAN.

GEROPHARM-Bio OJSC
142279, ógbè Moscow, ógbè Serpukhov, r.p. Obolensk, ụlọ 82, ikp. 4

Ntụziaka a ga-enye onye ọrịa

Nweghị ike iji ọgwụ ahụ ma ọ bụrụ na eburu ụzọ gosipụta na ngwọta ahụ.
Usoro ogwu maka insulin na vials

Ọ bụrụ na onye ọrịa ahụ na-eji naanị otu ụdị insulin

1. Sapoo akpụkpọ ahụ rọba nke vial ahụ
2. Dọrọ ikuku banye ntụtụ na olu nke kwekọrọ na insulin chọrọ. Mee ka ikuku banye n’ime karama insulin.
3. Tụgharịa vial ya na sirinji na kpoo ihu ya ma dọrọ ọgwụ insulin chọrọ ka ọ banye n'ime sirinji. Wepu agịga na vial ma wepu ikuku site na sirinji. Lelee ma ọ bụrụ na ọgwụ insulin dị ziri ezi.
4. Gbanye ozugbo.

1. Ighasa membranes roba nke vials.
2. Ngwa ngwa tupu ịkpọ, kpọghee paịlị nke insulin na-arụ ọrụ (“igwe ojii”) n'etiti ọbụ aka gị ruo mgbe insulin na-acha ọcha ma nwee urukpuru.
3. Na-anakọta ikuku n'ime sirinji na olu nke kwekọrọ na insulin insulin nke urukpuru. Tinye ikuku n'ime vial insulin na urukpuru wee wepu agịga na vial ahụ.
4. Denye ikuku n'ime sirinji ya na ọnụego insulin na-eme ka nwa oge (“transperent”). Mee ikuku n'ime karama insulin doro anya. Tụgharịa karama ahụ jiri sirinji kpoo ma kpọnyere ọgwụ chọrọ ka insulin “doo anya” dị ọcha. Wepụ agịga ma wepụ ikuku si sirinji. Lelee dose ziri ezi.
5. Tinye insulin ahụ “urukpuru” wee banye agịga ahụ na paịpụ, gbanye vial ya na sirinji kpodoro isi ala wee pịa insulin chọrọ. Wepu ikuku si na sirinji ma lelee ma ogwu a ziri ezi. Gbanye ngwakọta insulin anakọtara ozugbo.
6. Jiri insulin mgbe nile n'otu usoro dị ka akọwara n’elu.

• Ọ dị mkpa iji mmiri meghee mpaghara anụ ahụ ebe a ga-abanye insulin.
• Site na iji mkpịsị aka abụọ, kpoo mkpo anụ, tinye agịga n'ime isi mkpanaka ahụ n'akụkụ ihe dị ka ogo 45, ma gbanye insulin n'okpuru anụahụ.
• Mgbe ịgba ntụtụ ahụ, agịga kwesịrị ịdị n’okpuru anụ ahụ ma ọ dịkarịa ala 6 sekọnd, iji hụ na etinye insulin ahụ kpamkpam.
• Ọ bụrụ na ọbara apụta na ebe a gbanye ọgwụ were agịga, jiri nwayọ were pipụ mmiri dị na mmiri (dịka mmanya).
• Ọ dị mkpa ịgbanwe saịtị ịgba ntụtụ.

Ozi izugbe

Ebumnuche a bụ iji belata ịta shuga. Akụkụ bụ isi ya bụ insulin nke mmadụ.

Na mgbakwunye na ya, ihe mejupụtara ọgwụ ahụ gụnyere:

Rosinsulin dị ka ọgwụ nkwụ ụgwọ. Ọ nweghị agba na-enweghị isi.

Ọgwụ nwere ọtụtụ iche:

1. P - a na-eji ya eme ihe n’onwe ya.
2. C - ihe a na-eme bụ oge ọkara.
3. M - aha ọzọ - Rosinsulin mix 30-70. Ọ mejuputara ihe abuo: insulin soluble (30%) na insulin insulin (70%).

N'akụkụ a, ọgwụ ndị edepụtara nwere ụfọdụ ọdịiche, ọ bụ ezie na n'ozuzu ụkpụrụ nke omume ha bụ otu.

Ekwesịrị iji ọgwụ a mee ihe naanị dị ka dọkịta si kwuo, ebe ọ bụ naanị site n'aka ya ị nwere ike ịnweta ntụziaka ziri ezi. Na-enweghị ya, ọgwụ a nwere ike ịdị ize ndụ ọbụlagodi ndị ọrịa ahụ e gosiri ya.

Mwepụta wepụtara ya na ihe mejupụtara

“Rosinsulin” na-ezo aka ọgwụ ọgwụ hypoglycemic. Dabere na nzipu ekpughepu nye ọgwụ na oge ole, enwere:

• “Rosinsulin S” na-ezo aka ọgwụ ọjọọ,
• "Rosinsulin R" - obere ihe,
• Rosinsulin M bụ nkwadebe ejikọtara ọnụ.

Ọgwụ bụ insulin, nke a na-enweta site na ahụ mmadụ naanị site na mgbanwe DNA. Dịka akọwapụtara na ntuziaka maka ojiji nke Rosinsulin C, ụkpụrụ nke usoro a dabere na njikọta nke ihe mejupụtara ọgwụ ahụ na mkpụrụ ndụ. N'ihi nke a, etolitewo insulin.

Ọgwụ bụ nkwusioru ezubere maka nchịkwa subcutaneous. Nsonaazụ ya bụ nke kachasị n'ihi ọdịnaya nke insulin-isophan na ihe mejupụtara. Nke a bụ ọgwụ na-acha ọcha nke nwere obere isi awọ. Ọ bụrụ na enweghị ịma jijiji, mgbe ahụ, a na-ekesa ya na mmiri dị ọcha na sedimenti. Ọ bụ ya mere dịka ntuziaka ahụ si dị, tupu iwebata ọgwụ ịchọrọ ịma jijiji ntakịrị.

Ogwu a nwere ezigbo onu ahia. Ntụziaka maka iji “Rosinsulin R” na-atụ aro na ngwaọrụ a bụ insulin na-arụ ọrụ oge dị mkpirikpi. Ọ na - emekọrịta ihe n'ụzọ dị mfe na onye nnabata pụrụ iche na sel ahụ, ebe ọ na - akpụkọta ihe nnabata nke insulin.

N'oge ọgwụgwọ a ọgwụ, glucose njikọ n'ime sel abụba na imeju na-abawanye. Ihe ndị bụ isi na-abanye na mkpụrụ ndụ akwara, na-akpali ọrụ nke usoro intracellular.

N'ihi ịba ụba protein protein, ịba ụba nke glucose na ọbara na mmebi nke glycogen belata. Mgbe ịgba ntụtụ ahụ, usoro ọgwụgwọ na-amalite n'ime nkeji iri atọ. Oge ihe ị na-eme site na otu ọgwụ dị ihe dịka awa asatọ. Uru bara uru dabere na usoro onunu ogwu, usoro na uzo ochichi.

A na-egosi ọgwụ a "Rosinsulin C" n'ụdị isophane na oge ogo ọrụ. Ọgwụ na - enyere aka belata mkpụkọ glucose dị n'ọbara, na - eme ka nnabata ya na - abawanye site na anụ ahụ. Nke a na-ebelata ọnụego glucose na-emepụta site na imeju. Mgbe iwebata ọgwụ ahụ, ihe mejupụtara ọgwụgwọ ahụ malitere ime ihe n'ime awa 2. A na - enweta nsonaazụ kachasị mgbe awa 12 gachara. Mmetụta ọgwụgwọ ahụ na-adịgide otu ụbọchị.

Onye ka ekenyebere

Tupu ịmalite ọgwụgwọ, a ga-amụ ntuziaka maka ojiji yana nkọwa nke “Rosinsulin S” iji mara kpọmkwem ihe edepụtara ọgwụ ahụ yana otu esi eji ya. Jide n'aka na ị gakwuru dọkịta, ọ dị mkpa iji chọpụta nha kwesịrị ekwesị nke iji ya. Amachibidoro ịzụrụ ma jiri ọgwụ eme ihe n'echeghị eche, ebe enwere ike nsonaazụ na-adịghị mma. Ndị dibia bekee na-atụ aro ị theụ ọgwụ ahụ n’ihu ọrịa ndị dị ka:

• ụdị 1 na ụdị ọrịa shuga 2
• ọrịa shuga n’oge ime
• na mgbe a gbasịrị akwụkwọ ma ọ bụ oge izizi.

Na mgbakwunye, edepụtara ọgwụ a na enweghị nsonaazụ sitere na ị otherụ ọgwụ hypoglycemic ndị ọzọ, yana mgbakwunye na usoro ọgwụgwọ bụ isi.

Ọgwụ

Site na ntuziaka maka ojiji, “Rosinsulin C” na-ezo aka na nhazi ezubere maka nlekọta n'okpuru anụahụ. A hotara usoro onunu ogwu n’iburu n'uche nchoputa na ogo glucose di n’ime obara. Tupu ịmalite ọgwụgwọ, ịkwesịrị ịga hụ dọkịta iji gbakọọ usoro ọgwụgwọ. Nkezi onunu ogwu akwadoro usoro dabere n’usoro ogwu. 1 ml nke nkwusioru nwere ihe ruru 100 IU.

Dabere na ntuziaka maka ojiji, Rosinsulin M ka etinyere ya na usoro nke 0.5-1 IU kwa kilogram nke ịdị arọ onye ọrịa. Na-esote, a na-atụle njirisi nke mejupụtara ọbara na glucose, a na-ahọrọkwa usoro ọgwụgwọ kachasị mma.

Dịka akọwapụtara na ntuziaka maka ojiji a na-enye "Rosinsulin R" na nkeji iri anọ kwa ụbọchị. Usoro nchịkwa na-adabere na ọnụ ọgụgụ ọbara tupu nri oriri na mgbe nri gasịrị. Enwere ike ịnye ọgwụ ahụ:

• uzo ozo
• intramuscularly
• intravenia.

Ọtụtụ mgbe, Rosinsulin R na-achịkwa subcutaneously. O buru na achoputara oria mamiri di oria ma obu ekpughere ya oria, ana enye ogwu ogwu ahu ka oburu ya Na monotherapy, a na-eji ọgwụ ahụ ugboro atọ n'ụbọchị. N'ọnọdụ ụfọdụ, ugboro ole usoro nlekọta ọgwụ ahụ ruru ugboro isii kwa ụbọchị. Iji zere lipodystrophy na atrophy, a na-agbanwe saịtị nsị oge ọ bụla.

Dabere na ntuziaka maka ojiji, Rosinsulin S ka edeputara na usoro ọ na-erughị 24 IU. A na-ahụ ọgwụ ahụ 1-2 ugboro n'ụbọchị. Onye nrụpụta na-atụ aro ịgbanwe mpaghara ntụtụ oge ọ bụla. A na-ewere ọgwụ ahụ nkeji iri atọ tupu nri ụtụtụ. N'ọnọdụ ụfọdụ, a na-enye onye ọrịa ahụ ọgwụ mgbochi intramuscular, a machibidoro nchịkwa mgbochi.

Tupu iji ọgwụ ahụ, ịkwesịrị ikpo ya ka ọ kpoo okpomoku.Ikwesiri ịkwanye karama ahụ maka ikesa ọgwụ ọzọ. Ọ bụ dọkịta na-ekpebi ebe nlekọta ọrụ. Nke a bụ mgbidi afọ, apata ụkwụ, ubu ma ọ bụ ikpere.

Na ọnọdụ ọkọlọtọ, dị ka ntuziaka maka ojiji a na-enye Rosinsulin N iwu maka 8-24 IU otu ugboro n'ụbọchị. Ọ bụrụ na onye ọrịa nwere mmetụta dị elu na insulin, mgbe ahụ, a na-enye ọgwụ ahụ na obere usoro onunu ogwu, yana jiri mmetuta belata, ọnụọgụ ahụ karịrị 24 IU kwa ụbọchị.

Ime

Dịka ekwuru na ntuziaka maka ojiji, enwere ike iji Rosinsulin C n'oge ime na inye nwa ara maka ọgwụgwọ, ebe ọ bụ na ihe ndị dị n'ọrụ anaghị abanye na Plasenta.

Tupu ịmalite ịtụrụ ime, a na-atụ aro ịlele ọbara maka ọdịnaya shuga. N'ihe banyere njiri mara ọhụụ, dọkịta ahụ depụtara Rosinsulin. Mgbe ị na-enye nwa ara, a na-ahapụ ya ka ọ useụọ ọgwụ a, ebe ọ bụ na enweghị ozi gbasara etu esi abanye ya n’ime mmiri ara.

Jiri na nwata na nká

Enwere ike iji "Rosinsulin" na-emeso ụmụaka, agbanyeghị, ịkwesịrị idozi usoro ọgwụgwọ. Ọ dịkwa mkpa inyocha ọnọdụ ahụike yana akaebe.

A na-ekwe ka ọgwụ gwọọ ndị agadi, mana a ga-eji ya nke ọma, ebe ọ bụ na ha nwere ohere dị elu nke ịrịa hypoglycemia na iwe dị ọkụ nke ọrịa ndị ọzọ na - ebu ibu.

Ihe ngbanwe

Tupu iji ọgwụ ahụ, ọ dị mkpa ịmụ ntuziaka maka ojiji nke "Rosinsulin C". Ọnụahịa ọgwụ a 926 rubles. Amachibidoro ya iji ya mee ihe na enweghị dọkịta. Nke a bụ n'ihi mbelata nke glucose na ụkpụrụ dị oke mkpa.

Iji gbochie mmepe nke nsogbu, ịkwesịrị ịgbaso ntuziaka ahụ nke ọma, ma were ọgwụ mgbochi. Amachibidoro ya iji ngwa a mgbe ọnụnọ nke ọgwụ na -eme ka mmiri ọgwụ dị, yana n'ihe gbasara shuga dị ala.

Nsonaazụ

Iji 'Rosinsulin' eme ihe n'ụzọ na-adịghị mma gụnyere ahụ mmadụ. Iji mee nke a, a na-atụ aro ka ịgbaso ọgwụ ndị dọkịta doro anya, emela mgbanwe na usoro ọgwụgwọ ahụ n'onwe gị. Nsonaazụ ndị enwere ike dị ka:

• obi ọgba aghara,
• akpụkpọ anụ ahụ,
• pallor
• isi ọwụwa
• ọsụsọ na-ere ọkụ na ntụtụ ahụ,
• arịa ọbara ọbara.

Ọ bụrụ na mmeghachi omume na-adịghị mma, ị ga-agakwuru dọkịta mgbe niile ka ị gbanwee ọgwụgwọ ahụ.

Mkparịta ụka ọgwụ ọjọọ

Ọgwụ "Rosinsulin" dabara adaba maka ọgwụgwọ dị mgbagwoju anya yana ọgwụ ndị ọzọ. Tupu ịmalite ijikọ ọgwụgwọ, ịkwesịrị ịgakwuru dọkịta. Ọ ga-ahọta, ma gbakọọ usoro onunu ogwu, na-eburu n'uche mmekorita nke ihe ndị nọ n'ọrụ.

Iji kpachara anya, ịkwesịrị iwere "Rosinsulin" yana ụzọ ndị ọzọ ezubere iji mee ka ọkwa glucose ọbara dị mma. A na-ahụta mmebi nke nsonaazụ achọrọ na nchịkwa imekotaotu oge ya na diuretics, ọgwụ mgbochi, antidepressants.

Analogues nke ọgwụ

Tupu ịzụta ọgwụ ahụ, ịkwesịrị ịmụ ntuziaka maka ojiji na nyocha nke "Rosinsulin" Ọnụ ahịa ọgwụ ahụ ruru 100 rubles. O nwere otutu ogwu ndi ozo nke edeputara ma oburu na enwere contraindications. N'etiti analogues, odi nkpa ka ekpughari dika:

Ọgwụ "Novomix" bụ insulin nke-abụọ. A na-amata ya site na ọsọ ya na arụmọrụ ya. Edebeghị ya maka ụmụaka na-erubeghị afọ isii. Ọtụtụ mgbe n'ebe a na-agba ntụtụ, allergies na-apụta.

Ọgwụ "Insuman" 3 ụdị emereme. A na-eji ya maka ọgwụgwọ ụmụaka na ndị okenye. Ngwá ọrụ a anaghị akpasu nsogbu ndị ọzọ ọ na-akpata.

A na-eji ọgwụ ahụ "Protafan" eme ihe naanị na subcutaneously, a na-eji ya agwọ ndị ọrịa nke afọ ọ bụla. Womenmụ nwanyị dị ime nwere ike iji ya na n'oge a na-enye nwa.

Ndụmọdụ ndị dọkịta

Ndị dọkịta na-ekwu na n’oge ịmụ nwa na mgbe a na-amụ nwa, mkpa insulin na-ebelata nke ukwuu. N'okwu a, nwanyị ga-anọ n'okpuru ndị dọkịta. Ndị dọkịta kwuru na ọgwụ a nwere ezigbo nsonaazụ site na iji ya mgbe niile.

Ha na-arụ ụka na ọgwụ a enweghị ihe mgbochi ọ bụla na nsonaazụ ya ma ọ bụrụ na ejiri ya n'ụzọ ziri ezi.

Nyocha nyocha Ndidi

Nyocha nke ndị ọrịa mamịrị nwere ahụmahụ ọgwụ a na-akacha mma. Ha na-ahụta ohere dị n'iji, ike ijikọ ọtụtụ insulin. Agbanyeghị, enwere ndị ọ na-adabaghị kpamkpam.

Ọtụtụ na-ekwu na nke a bụ ngwaahịa ụlọ, mana na ogo ọ dị ala karịa nke mba ọzọ. Ma n'ọnọdụ ụfọdụ, ọ na-akpalite oke hypoglycemia.

Etu esi eji: usoro onunu ogwu na usoro ọgwụgwọ

A na-ekpebi ọ̀gwụ na ụzọ nchịkwa nke ọgwụ a n’otu n’otu n’ebumnuche nke glucose dị n’ọbara tupu nri na 1-2 awa mgbe ị risịrị nri, yana kwa dabere na ogo glucosuria na njiri mara usoro ọrịa ahụ.

A na-elekọta ọgwụ ahụ s / c, na / m, na / n'ime, 15-30 nkeji tupu eri. Routezọ nchịkwa kachasị na-ahụkarị bụ sc. Na ketoacidosis na-arịa ọrịa shuga, coma mamịrị, n’oge usoro ịwa ahụ - in / in na / m.

Site na monotherapy, oge nchịkwa na-abụkarị ugboro 3 kwa ụbọchị (ma ọ bụrụ na ọ dị mkpa, ruo ugboro 5-6 kwa ụbọchị), a na-agbanwe saịtị injection oge ọ bụla iji zere mmepe nke lipodystrophy (atrophy ma ọ bụ hypertrophy nke subcutaneous fat).

Nkezi ubochi ubochi bu 30-40 PIECES, na umuaka - 8 PIECES, mgbe ahu na otu ubochi ubochi - 0,5-1 PIECES / n'arọ ma obu 30-40 IGBOKWU 1-3 ugboro kwa ubochi, oburu na odi - ugboro 5-6 kwa ubochi. N ’ọgwụ kwa ụbọchị karịrị 0.6 U / n'arọ, a ga-enye insulin ahụ n’ụdị ntụtụ 2 ma ọ bụ karịa na akụkụ dị iche iche nke ahụ.

Ọ ga-ekwe omume ijikọta ya na insulins ndị na-eme ogologo oge.

A na - anakọta azịza insulin site na vial ahụ site na iji obere agịga na - egbu egbu na - ehichapu ọkpọkọ roba kpochapụrụ okpu aluminom na ethanol.

Omume ọgwụ

Nkwadebe insulin na-adị obere. Withme ka otu onye nnabata nke akpụkpọ ahụ dị na sel na - emekọ ihe, na - eme ka ihe nnabata nke insulin. Site na ịba ụba njikọta nke cAMP (na abụba abụba na akwara akwara) ma ọ bụ banye n’ime sel (akwara), insulin receptor complex na-akpali usoro intracellular, gụnyere njikọ nke ọtụtụ enzymes isi (hexokinase, pyruvate kinase, glycogen synthase, wdg). Mbelata nke mkpokọta glucose na ọbara bụ n'ihi mmụba na njem ya na intracellular, ịba ụba na nnweta nke anụ ahụ, mkpali nke lipogenesis, glycogenogenesis, protein protein, mbelata ọnụego glucose mepụtara site na imeju (ibelata na mmebi nke glycogen), wdg.

Mgbe agwọchara sc, mmetụta ahụ na-apụta n'ime oge 20-30, rute oke mgbe awa 1-3 na-adịgide, dabere na ọnụọgụ, 5-8 awa. Ogologo oge ọgwụ ahụ dabere na usoro, usoro, ebe nchịkwa ma nwee njiri dị iche iche nke onwe onye. .

Nsonaazụ

Mmeghachi omume nfụkasị ahụ (urticaria, angioedema - fever, ụkwara ume ọkụ, mbelata ọbara mgbali),

hypoglycemia (pallor nke anụ ahụ, ịba ụba ọsụsọ, ọsụsọ, palpitations, ịma jijiji, agụụ, agụụ, nchekasị, paresthesias n'ọnụ, isi ọwụwa, ụra, ehighị ụra nke ọma, ụjọ, ọnọdụ ịda mbà n'obi, mgbakasị ahụ, omume na-enweghị atụ, enweghị mmeghari, ikwu okwu na nsogbu okwu na ọhụụ), hypoglycemic coma,

hyperglycemia na ọrịa shuga acidosis (na obere doses, injections ski, nri na-adịghị mma, megide ọrịa azụ na ọrịa): iro ụra, akpịrị ịkpọ nkụ, agụụ nri, ọdịdị ihu, belata.

isi mmụọ (ruo na mmepe nke precoatose na coma),

nsogbu adịghị ahụ anya (yana oge mmalite ọgwụ),

mmeghachi omume immunological na insulin nke mmadụ, mmụba na ụzọ nke ọgwụ mgbochi insulin, mmụba nke glycemia,

hyperemia, itching na lipodystrophy (atrophy ma ọ bụ ọbara mgbali nke abụba subcutaneous) na ntụtụ.

Na nmalite ọgwụgwọ - mgbakasị ahụ na mgbakasị ahụ (na-adị nwa oge ma na-apụ n'anya site na iji ọgwụgwọ na-aga n'ihu).

Mmekorita

N ’ogwu ọgwụ ekwekọghị na ọgwụ nke ọgwụ ndị ọzọ.

A na - eme ka mmetụta hypoglycemic dị na sulfonamides (gụnyere ọgwụ hypoglycemic ọgwụ, sulfonamides), MAO inhibitors (gụnyere furazolidone, procarbazine, selegiline), ndị na-egbochi carbon anhydrase inhibitors, ndị na-egbochi ACE, ndị na-egbochi NSAIDs (gụnyere salicylates), anabolic (gụnyere stanozolol, oxandrolone, methanedienone), androgens, bromocriptine, tetracyclines, clofibrate, ketoconazole, mebendazole, theophylline, cyclophosphamide, phenfluramine, Li + na njikere, pyridoxine, quinidine, quinine, chloroquin.

Hypoglycemic mmetụta nke isi glucagon, ibu hormone, corticosteroids, onu gbochie afọ, estrogens, thiazide na "loop" diuretics, BCCI, thyroid homonụ, heparin, sulfinpyrazone, sympathomimetics, danazol, tricyclics, clonidine, BCCI, diazoxide, morphine, wii wii, nicotine, phenytoin , epinephrine, H1-histamine na-anabata ihe mgbochi.

Beta-egbochi, reserpine, octreotide, pentamidine nwere ike ịkwalite ma mee ka ike gwụ hypoglycemic mmetụta nke insulin.

Rinsulin P - ntuziaka maka ojiji

A na-ele Rinsulin P anya insulin mmadụ. E nwetara ya n'ihi iji teknụzụ DNA recombinant. Insulin na-agbanwe agbanwe bụ mmiri na-enweghị agba, mmiri doro anya. Ezubere ọgwụ a maka ịgba ntụtụ, intramuscularly na subcutaneously. Ebumnuche hypoglycemic bụ maka ndị ọkwa shuga dị n'ọbara ha wee daba oke.

Ngwakọta na ụdị ntọhapụ

Ngwọta maka ntụtụ

Insulin insulin na-eme mmadụ

Ndị na-ahụ maka ihe dị adị na nkwadebe: glycerol (glycerin) - 16 mg, metacresol - 3 mg, mmiri d / i - ruo 1 ml. Olu nke karama a bu 10 ml. Edebere ya n’ime igbe kaadiboodu, ngwunye ihe na-acha odo odo nwere ngwongwo ise. Otu iko vidiyo nke etinyebere na pen sirinji ọtụtụ nwere, nke emere maka injee ugboro ugboro, na-ejide 3 milimita.

Pharmacodynamics na pharmacokinetics

Ọ bụ n'ọbara ihe oriri insulin n'ime ọbara na-ekpebi oge ọ ga-eji ọgwụ ahụ dabere na ihe anọ:

• si na ọgwụ ọgwụ (ego insulin injection),
• site na ịta insulin na ọgwụ
• saịtị ịgba ntụtụ (apata ụkwụ, ụkwụ, afọ),
• usoro nchịkwa (intramuscularly, intravenously, subcutaneously).

Na nkezi, mgbe nchịkwa gasịrị, insulin amalite ime ihe na nkeji 20-30, a na-enweta mmetụta kachasị n'etiti awa 1-3. Nsonaazụ nke ọgwụ, dabere na dose ahụ, dịkarịa ala 8 awa. Mwepu nke ọgwụ bụ na a na-ekesa ihe ngwọta a na - ekeghị n ’ụbụrụ akwara. A na-ebibi insulinase n'ime imeju na akụrụ. A na - ekepụta Rinsulin, dịka iwu, site na akụrụ.

Usoro onunu ogwu na nhazi

Ọ bụ dọkịta ga-ekpebi ị doseụ ọgwụ yana ụzọ ọ ga-esi eji ọgwụ ahụ eme ihe.

Usoro nchịkwa Subcutaneous bụ ụzọ kachasị. N'ime ọbara na intramuscularly, a na-a drugụ ọgwụ ahụ n'ọnọdụ dị oke njọ, dịka ọmụmaatụ, nwere ịwa ahụ na-abịanụ ma ọ bụ coma mamịrị.

A na - enye insulin 20 nkeji iri tupu nri nke nwere carbohydrates. Ihe ngwọta kwesịrị ịdị n ’ụlọ okpomọkụ.

Ọgwụ a na-abanye n'ime mgbidi akụkụ ihu, ebe a na-enweta mmịcha kachasị. Nwere ike ịnọgodi n'apata ụkwụ, mana, ma ọ bụ mpaghara na-adọrọ adọrọ n'ubu. Mgbe ị na - eji insulin subcutaneously, ọ dị mkpa ka ị ghara imerụ arịa ọbara. Can nweghị ike ịnye ọnụ n'otu ebe ọtụtụ oge n'usoro, enwere ihe ize ndụ nke lipodystrophy.

N'ihe banyere monotherapy, ekwesịrị ịmebata ọgwụ ahụ n'ime ahụ ugboro atọ n'ụbọchị (maka ụfọdụ ndị ọrịa - ugboro 5-6). Dabere na ntinye glucose n'ọbara, ị doseụ ọgwụ kwa ụbọchị sitere na 0.3 ruo 1 IU / n'arọ nke oke ahụ.

Anabataghị iji katriiki ma ọ bụrụ na azịza agbanwewo ma ọ bụ ọhụụ na ya. Enwere ike iji katrij na agịga otu oge.

Ojiji nke mkpịsị ọrịre ga-emezurịrị dịka ntuziaka onye nrụpụta si dị. Tupu ịmalite usoro ahụ, ịkwesịrị iwepu otu sirinji na friji ma chere ruo mgbe insulin etinyere na-ekpo ọkụ ụlọ, wee jiri agịga ahụ ị nwere ike tinye ọgwụ ahụ. Mgbe ogwu ogbugba ahụ, ekwesịrị ịhapụ ya na okpu ma wepụ ya ozugbo maka nchekwa.

Analogs Rinsulin P

Enwere ọnụ ọgụgụ analogues zuru oke nke ọgwụ ahụ, ma ndị Russia ma ndị mba ọzọ.

• NRM (Novo Nordisk, Denmark),
• Biosulin (Pharmstandard-UfaVITA, Russia),
• Gensulin R ("Bioton S. A., Poland),
• Vosulim-R (Wokhard Ltd, India),
• Insuran R (oflọ Akwụkwọ Bioorganic Chemistry RAS, Russia),
• Rosinsulin R (Mkpokọ Mmanụ a ,ụ, Russia),
• Monoinsulin CR (Belmedpreparaty, Belarus),
• Hum Rar R 100 Osimiri (Indar, Ukraine),
• Humulin Regular (Lilly France, France).

Rinsulin R bụ ọgwụ GEROPHARM-Bio mepụtara. .Ihe atụ emlele maka ịlele ọgwụ n’ụlọ ọgwụ dị na Moscow:

Ngwaọrụ nọ n'ọrụ nke P na C

A na-atụle Rosinsulin P insulin nke na-adị mkpụmkpụ. Ọ na - emekọrịta ngwa ngwa na ihe nnabata pụrụ iche n'ahụ nke dị na sel, na - akpụpụta ọgwụ nnabata nke insulin. Megide usoro ọgwụgwọ, njikọta CAMP n'ime akwara na abụba na-abawanye. Ihe mejupụtara ọgwụ ahụ na-abanyekwa mkpụrụ ndụ akwara, na-akpali ọrụ nke hexokinase na usoro intracellular ndị ọzọ.

N'ihi ịba ụba protein protein, ịba ụba nke glucose na ọbara na mmebi nke glycogen belata. Mgbe ọ gbasachara, ekpughere ekpughe maka nkeji iri atọ. Oge ọ ga-eji were otu mee ruru awa asatọ. Uru nke ihe ngosi a dabere na usoro onunu ogwu, uzo ya na ebe ochichi ya.

A gosipụtara Rosinsulin C dị ka insulin-isophan na-enwe mmetụta dị mma. Ọgwụ na -ebelata mkpụkọ glukos dị n'ọbara, na-eme ka mmụba ya site na anụ ahụ, na-eme ka lipogenesis dịkwuo elu. Nke a na-ebelata ọnụego glucose na-emepụta site na imeju.

Mgbe ogwu ogbugba, ihe mejupụtara amalite ime ihe mgbe awa 2 gachara. A na-enweta oke arụmọrụ mgbe awa iri na abụọ gachara. Ọgwụgwọ ahụ na-adịru otu ụbọchị. Uru nke ihe ngosi a na-emetụta oke na usoro ọgwụ a.

Ihe ngosi na contraindications

Ihe ngosi maka nhọpụta ọgwụ a dị ọtụtụ.

Ndị a gụnyere:

• ụdị 1 na ụdị ọrịa shuga mellitus 2 (na enweghị nsonaazụ ọgwụgwọ site n'aka ndị nnọchianya hypoglycemic nke ọnụ ma ọ bụ na-arụ ọrụ nke ọma),
• ọrịa shuga nke mere n’oge afọ,
• ketoacidosis
• ketoacidotic coma,
• chọrọ insulin na-arụ ọrụ ogologo oge,
• ọrịa na-efe efe na ndị ọrịa mamịrị.

Njirimara ndị a chọrọ ọgwụgwọ site na ndị nwere insulin, mana ọnụnọ ha apụtaghị na ụdị ọgwụgwọ ahụ kwesịrị ịmalite ozugbo. Nke mbu, gbaa mbọ hụ na enweghi contraindications. Maka ha, ị na-ahapụkarị iji Rosinsulin.

A na - akpọ ndị isi contraindications:

Nchọpụta nke njirimara ndị a chọrọ nhọrọ nke ụzọ ndị ọzọ, ebe ọ bụ na iji Rosinsulin mee ihe nwere ike imebi emebi.

Ntụziaka maka ojiji

Iji nweta nsonaazụ, ekwesịrị iji ọgwụ ọ bụla dịka ntuziaka ahụ si dị. Ihe osise Rosinsulin anaghị enyere aka nke ukwuu, ebe ọ bụ na onye ọrịa ọ bụla nwere ike ịnwe njirimara chọrọ mgbazi usoro ihe omume yana usoro ọgwụgwọ. Ya mere, achọrọ ntuziaka doro anya site na dọkịta.

A na-eji ọgwụ a eme ihe dị ka ọgwụ ntụtụ, nke enyere subcutaneously. Mgbe ụfọdụ, a na-anabata nchịkwa intraven ma ọ bụ intramuscular, mana ọ bụ naanị ọkachamara na-ebu ya.

A na-agbakọ ugboro nke injections na dose nke ọgwụ ahụ n'otu n'otu dabere na njirimara foto ahụike.Ọ bụrụ na enweghị atụmatụ ndị ọzọ, a na-eji 0-1-1 IU / kg nke ibu mee ihe kwa ụbọchị. N’ọdị n’ihu, a na-amụ mgbanwe mgbanwe glukos ọbara na-agbazi ọ̀tụ̀tụ̀ ọ bụrụ na ọ dị mkpa.

Mgbe ụfọdụ, a na-ejikwa Rosinsulin jikọta ya na usoro insulin na-eme ogologo oge. N'okwu a, a ga-agbanwe ọgwụ nke ọgwụ.

Ekwesịrị ịnye ọgwụ mgbochi tupu nri (maka nkeji 20-30). N'ụlọ, a na-eji ọgwụ eme ihe n'okpuru ala n'apata ụkwụ, ubu, ma ọ bụ mgbidi afọ. Ọ bụrụ na ọgwụ dọkịta nyere ya karịrị 0.6 IU / n'arọ, ekwesịrị ịkesa ya n'ọtụtụ akụkụ. Ekwesịrị ịgbanwere saịtị ndị agba agba ka enweghị nsogbu akpụkpọ.

Ntụziaka vidiyo maka iwebata insulin na mkpịsị sirinji:

Ndị Ọrịa na Nduzi Pụrụ Iche

Fọdụ ndị ọrịa chọrọ ịkpachapụ anya. Nke a bụ n'ihi njirimara nke ahụ ha, n'ihi nke Rosinsulin nwere ike imetụta ha n'ụzọ na-enweghị atụ.

Ndị ọrịa a gụnyere:

1. Childrenmụaka. N ’ọgwụ, amachibidoghị ọgwụ insulin, kama ọ chọrọ nlebara anya nke ndị dọkịta. Ewere ọgwụ nke ọgwụ a ka o nye ha obere karịa ọrịa shuga okenye.
2. Ime Ọgwụ a anaghị emerụ ụmụ nwanyị mgbe ha na-amụ nwa, ya mere, a na-ejikarị ya kpochapụ ihe mgbaàmà nke ọrịa shuga. Mana n'oge ime, mkpa insulin nwere ike ịdị iche dabere na oge a, yabụ ịkwesịrị ileru anya ọgụgụ gulite ma dozie akụkụ nke ọgwụ.
3. Ndị nne mụrụ nwa. A machibidoghị ha ọgwụ insulin. Ngwaọrụ nọ n'ọrụ ọgwụ nwere ike ịbanye na mmiri ara ara, mana ha enweghị mmetụta ọjọọ n'ahụ nwa ahụ. Insulin bụ protein protein nke ahụ nwatakịrị na-ahụkarị. Ma mgbe ị na-eji Rosinsulin, ụmụ nwanyị na-azụ nri kwesịrị ịdị na-eri nri.
4. Ndị okenye. Banyere mkpa ha nke ịkpachara anya bụ n'ihi mgbanwe ndị metụtara afọ. Mgbanwe ndị a nwere ike imetụta ọtụtụ akụkụ ahụ, gụnyere imeju na akụrụ. Ọnụnọ nke mmebi na arụ ọrụ akụkụ ahụ ndị a, ịmịpụrụ insulin na-ebelata. Ya mere, ndị ọrịa karịa afọ 65 ka a na-edenye ọgwụ nwetụrụ obere ọgwụ.

Ikwesiri iji nlezianya gwọọ ọgwụgwọ nke ndị mmadụ nwere ọrịa dị iche iche. Offọdụ n'ime ha na-emetụta ọrụ nke Rosinsulin.

A na - akpọ ụfọdụ n'ime ha:

1. Mmebi nke akụrụ. N'ihi ha, nsị nke ihe bekee na - arụ ọrụ nwayọ nwayọ, nke nwere ike ibute oke ha na nnabata hypoglycemia. Ya mere, ndị dị otú a kwesịrị iji nlezianya gbakọọ usoro onunu ogwu.
2. Pathology nke imeju. Site na nduzi nke insulin, imeju na-ebelata mmepụta glucose. Ọ bụrụ na enwere nsogbu na arụ ọrụ ya, enwere ike imepụta glucose na nwayọ nwayọ, nke na-ebute erughi ya. Nke a pụtara na a bụrụ na imebi iwu na arụ ọrụ nke ahụ a, a ga-belata ogo nke ọgwụ a.

Ọgwụ Rosinsulin naanị anaghị eme ka ihe ndị na-adọpụ uche na ikike itinye uche ma ọ naghị akwụsị imeghachi omume. Ọnọdụ hypoglycemic nke kpatara site na iji ihe ndị a eme ihe n'ụzọ na-ekwesịghị ekwesị. N'akụkụ a, ịnya ụgbọ ala na ihe omume ndị dị ize ndụ mgbe ị na-eji ọgwụ a bụ ihe a na-achọghị.

Usoro ọgwụgwọ

A na-a drugụ ọgwụ nke otu C ugboro 1-2 kwa ụbọchị. Onye nrụpụta na-adụ ọdụ oge ọ bụla ọzọ ịgbanwe mpaghara ntụtụ. A na-ewere ọgwụ ahụ nkeji iri atọ tupu nri ụtụtụ. N’oge na-adịghị anya, a na-enye onye ọrịa ahụ ọgwụ mgbochi Rosinsulin C ka a machibidoro nchịkwa ọgbụgba ọbara.

A na-ahọrọ usoro onunu ogwu n’otu n’otu. Ọ dabere na ihe glucose dị na mmamịrị na ọbara, njirimara nke ụzọ ọrịa ahụ. Na ọnọdụ ọkọlọtọ, o zuru ezu ịbanye 8-24 IU otu ugboro n'ụbọchị. Ọ bụrụ na onye ọrịa nwere mmetụta uche dị elu na insulin, a na-edenye ọgwụ ahụ na ntakịrị opekempe, yana jiri mmetụ belata - na usoro nke ihe karịrị 24 IU kwa ụbọchị. Ọ bụrụ na n’ehihie, usoro onunu ogwu akarịala 0.6, a na-awa abụọ n ’ebe dị iche iche. A na-anabata ndị ọrịa natara ihe karịrị 100 IU kwa ụbọchị na nnọchi insulin.

Ọgwụ Rosinsulin P bụ nke onwe ya. Usoro onunu ogwu na usoro itinye ihe dabere na onu ogugu tupu nri ma mgbe nri gasiri, ogo glycosuria. Administrationzọ Nchịkwa:

Ọtụtụ mgbe Rosinsulin P na-achịkwa subcutaneously. Ọ bụrụ na ekwenyela na ọria mamịrị ma ọ bụ gosipụta ya ahọpụtara, a na-achịkwa ihe mejupụtara ya. Site na iji monotherapy, a na-etinye ọgwụ ahụ ugboro atọ n'ụbọchị. N'ọnọdụ ndị a na-adịghị ahụkebe, ugboro ole nchịkwa na-eru ugboro 6 kwa ụbọchị. Iji zere atrophy, lipodystrophy, saịtị injection na-agbanwe oge ọ bụla.

Usoro ubochi kwa ubochi kariri nkeji iri anọ. Edebere ụmụaka na usoro nke 8 nkeji. Ọ bụrụ na enyere ihe karịrị 0.6 nkeji kwa 1 n'arọ nke ịdị arọ, a na-enye insulin ugboro abụọ yana n'akụkụ dị iche iche nke ahụ. Ọ bụrụ na ọ dị mkpa, a na-ejikọ Rosinsulin C yana insulin na-arụ ọrụ ogologo oge.

Mmeghachi omume ọjọọ

Ọgwụ nke otu ọ bụla a na-ekwu okwu nwere ike ịkpalite nfụkasị ụdị urticaria. Dyspnea apụtaghị obere oge, nrụgide na-ebelata. Ihe mgbaàmà ndị ọzọ na-adịghị mma nke Rosinsulin P na C:

• ehighi ura
• migraine
• agụụ na-adịghị mma
• nsogbu nsụhọ
• abawanye titter nke ọgwụ mgbochi insulin.

Na nmalite ọgwụgwọ mbụ, ndị ọrịa na-eme mkpesa nke edema na mgbakasị ahụ. Ọrịa na-apụ n'anya ozugbo enwere ike. A na-elebara ọnọdụ nke kalama ahụ anya. Tupu nchịkwa, a na-enyocha ihe ngwọta maka nghọta. Ọ bụrụ na e nwere ahụ ndị si mba ọzọ na mmiri ahụ, ejighị Rosinsulin eme ihe.

A na-ahazi usoro ị drugụ ọgwụ ahụ maka ọrịa, nsị thyroid, ọrịa Addison. Hypoglycemia na-etolite dị ka ihe mgbaàmà nke ịdoụbiga mmanya ókè. A na-egosiputa oria yiri nke a mgbe eji dochie Rosinsulin C na P na onye ozo. Ihe mgbaàmà ndị ọzọ nke ịdoụbiga mmanya ókè:

• vomiting
• afọ ọsịsa
• ibelata na ọrụ ọrụ.

Ọ bụrụ na ụlọ ọgwụ dị n'elu gosiri, a na-atụ aro ịgwa onye dibịa bekee. Ọtụtụ mgbe, a na-adụ ndị ọrịa ọdụ ịga ụlọ ọgwụ. A na-ahọpụta atụmatụ ndị a mgbe nyochachara nke onye ọrịa ahụ.

Ọ bụrụ na onye ọrịa ahụ nwere ọrịa imeju na akụrụ, a ga-ebelata mkpa ị medicationụ ọgwụ. Ntinye glucose nwere ike gbanwee mgbe a na-ebufere onye ọrịa na anụmanụ na insulin nke mmadụ. Ekwesiri ịnyefe ụdị ntụgharị a na ọgwụ. A na-eme ya n'okpuru nlekọta nke ndị dọkịta.

Ndụmọdụ ahụike

Ndị ọrịa mamịrị na-akwụsị ịdị ụtọ nke hypoglycemia site na iri shuga. Mgbe ọnọdụ ahụ kara njọ, a na-agbanwe ọgwụgwọ. Ọ bụrụ na onye ọrịa dị ime, ihe ndị a ka ị ga-elebara anya:

• N'ime oge ato 1, a na-ebelata ọgwụ a.
• N'ime oge nke abụọ na nke atọ, mkpa nke Rosinsulin na-abawanye.

N'oge ịmụ nwa na mgbe amuchara ịmụ nwa, amụbala mkpa ọgwụ ahụ ike dị. N’ebe a na-enye nwa ara, ndi nwanyi na-elebara ndi dibia anya kwa ubochi.

Site na echiche nke ọgwụ, Rosinsulin P na C ekwekọghị na ngwọta nke ọgwụ ndị ọzọ. A na - eme ka mmetụta hypoglycemic dị ukwuu site na oriri nke sulfonamides, monoamine oxidase inhibitors na enzyme angiotensin. A na - eme ka mmetụta ọgwụgwọ ahụ sikwuo ike site glucagon, glucocorticoids, mgbochi mkpịsị ọnụ, Danazole. Ndị na-egbochi Beta-egbochi na-ewusi ma na-akụda nsonaazụ Rosinsulin.