Usoro: ntuziaka na nyocha, ọnụahịa nke mbadamba

Metformin bụ nke biguanides, mmetụta hypoglycemic nke sitere na mbelata nkwụghachi insulin anụ ahụ, yana mmụba nke glucose na-aba ụba site na abụba na akwara. Ọgwụ ahụ na-egbochi ike ịmịnye glucose na eriri afọ, na-egbochi gluconeogenesis, na-eme ka metabolism dị ọcha ghara ịdị ike. Metformin nwekwara mmetụta bara uru na arịa ọbara, na-egbochi nsogbu vaskụla n'ọrịa shuga.

Ọgwụ ahụ adịghị akpali mkpụrụ ndụ beta na mmepụta insulin, ya mere ọ dị nchebe n'ihe gbasara mmepe nke hypoglycemia.

Mgbe ọ gbasasịrị, oke ọgwụgwọ ọgwụgwọ na-etolite ma elekere abụọ gachara, oge ngụkọta oge ahụ bụ awa 6.

A na-egosi ọgwụ ahụ maka ịgwọ ụdị ọrịa shuga 2, karịsịa oke ibu, na enweghị nri na mmega ahụ.

Ihe ngbanwe

• ebumnuche nke lactic acidosis (ịkpakọba na anụ ahụ lactic acid)
• ketoacidosis
• ụdị shuga 1
• tụụrụ ime
• afọ ụmụaka
• hypoglycemia na ọrịa shuga
• oke imeju na akụrụ
• egbu egbu egbu
• ọrịa butere ọrịa obi
• hypersensitivity.

Usoro onunu ogwu na usoro ochichi

A na-edobe usoro onyonyo otu n'otu, na-eburu n'uche glycemia na glycosuria.

Usoro mbu nke formin bu 850 mg / day. N'ime izu abụọ, a na-eji nwayọ nwayọ nwayọ were rue ruo mgbe a ga-enweta njikwa glycemic. Idozi mmezi - mbadamba abụọ / ụbọchị.

Onyinye ego nke ụbọchị kacha bụ 3 mbadamba.

E kwesịrị ikenye ka ihe karịrị ihe dị ka 1 mbadamba ụzọ abụọ. Jiri ọgwụ ma ọ bụ mgbe nri gasịrị. Mgbe ewere ya tupu nri, oge iji nweta ihe ọgwụgwọ ọgwụgwọ agbatịla.

Maka ndị ọrịa mgbe afọ 60 gachara ma nwee ajọ metabolic dị ukwuu, mụbaa usoro ọgwụgwọ nke ọma na nlezianya.

Nsonaazụ

• lactic acidosis (nwere oke umeji ma ọ bụ akụrụ, oke mmanya na-egbu egbu, nbibi obi)
• hypoglycemia
• nsonso na-emetụta eriri afọ: nri ọgbụgbọ, afọ ọsịsa, ọgbụgbọ, ụtọ ọla, mgbu afọ (na-apụta na mmalite ọgwụgwọ ma ọ bụ na-abawanye oke na dose)
• malabsorption nke vitamin B12 na B9
• nfụkasị ahụ akpịrị.

Edepụtara mpempe akwụkwọ maka monotherapy ma ọ bụ yana yana sulfonylurea ma ọ bụ insulin. A na-eme ọgwụgwọ a na-ejikọta ya na insulin n'ụlọ ọgwụ ruo mgbe etolite usoro ọgwụgwọ kachasị mma iji gbochie mmepe nke hypoglycemia.

N'oge a na-eji ọgwụ ndị ọrịa eme ihe, ọ dị mkpa ịchịkwa ọkwa nke serin creatinine otu ugboro kwa ọnwa isii, na otu ugboro n'afọ iji nyochaa ọbara maka ọkwa vitamin B12.

N'iji ọgwụ a na-eji ya eme ihe, a ,ụrụma na-adịghị mma.

Ojiji nke formin na ogwu iji gwọ oria oria nwere ike bulite ya ma obu wedaa ya hypoglycemic. Ya mere, n'otu oge ahụ ọgwụ ga-achịkwa otu oge nke ọtụtụ ọgwụ ọgwụ, na-eburu n'uche njikọrịta nke ọgwụ ọjọọ.

Ntuziaka maka iji ọgwụ ahụ

N'ezie, ihe fọrọ nke nta ka ọ bụrụ ndị ọrịa na-anwale mgbe niile ntuziaka nke ndị nrụpụta tupu ị usingụ ọgwụ. Nke a bụkwa mkpebi dị mma. N'ezie, naanị na nke a, ọ ga - enwe ike ikpebi n'onwe gị nke mmetụta ọ bụla nwere ike ịdakwasị gị n'ihi nchịkwa na - adịghị mma, yana otu esi emetụta anụ ahụ na mmetụta dị mma ọ nwere site n'ọgwụ ogologo oge nke ọgwụ.

Iji malite, ekwesịrị iburu n'uche na a na-enye ọgwụ ahụ n'ụdị mbadamba. Enwere ngwugwu nwere ngwugwu iri atọ, ma enwere ndị dị na iri isii.

E gosipụtara mmetụta ọgwụ bụ isi nke Formin Pliva n'eziokwu ahụ na mgbe ejiri ogologo oge were ya, ọ ga-ekwe omume belata ọkwa glucose dị n'ọbara onye ọrịa. Ọzọkwa, a na-atụ aro ka ọ were ya nke ọma nye ndị ọrịa na - enweghị insulin, ya bụ, ndị na - etinyeghị insulin.

Ngwongwo a bara uru bu nke a puru omume n'ihi na isi ihe na - aru ​​oru na - akwalite ojiji kwesiri ekwesi. N'ihi ya, usoro niile nke gluconeogenesis nke na-apụta na umeji na-egbochi. A na-ebelatakwa ohere ịnabata carbohydrates dị na ngọngọ nke mmadụ ọ bụla.

Akụkụ ọzọ dị mma nke na-eme ka Usoro Pliva pụta bụ na ọ na-eme ka mmụba nke uru ahụ niile dị na insulin. Ọ bụ ya mere, ọ ga-ekwe omume belata ọkwa glucose dị n’ọbara onye ọrịa.

N’ezie, ọ bụrụ na anyị na-ekwu maka ma ọ ga-ekwe omume ịbawanye usoro insulin n’ahụ n’arụ n’ihi ị ofụ ọgwụ ogologo oge, mgbe ahụ na nsonaazụ a agaghị enwe isi.

Mana amara na mgbe itinyere Mịnịstrị, enwere mbelata na ụba nke triglycerides n'ọbara onye ọrịa, yana mbelata n'ọkwa coagulability nke mmiri ahụ a kpọtụrụ aha.

A na-ewere ọgwụ ahụ n'ime, a na-enweta mkpo kachasị nke ihe ndị bụ isi na ahụ n'ime awa abụọ mgbe nchịkwa ahụ gasịrị. Ma njikota ikpeazụ nke ọbara ya pụtara mgbe awa isii gachara.

Apụrụ ya site na onye ọrịa ahụ site na akụrụ.

Mgbe ịmalite ị theụ ọgwụ ọjọọ?

Ekwuputala ya n’elu na ọ bara uru ịmalite ị onlyụ ọgwụ naanị mgbe ọ bụla nyochachara dọkịta gị. Can nweghị ike ịmalite iji ọgwụ eji eme ihe kwụụrụ onwe ya.

Ọtụtụ mgbe, n'ime ụdị ndị ọrịa a na-atụ aro maka Formin Pliva, a na-achọpụta ndị ọrịa ahụ nwere ụdị shuga 2.

Na-abụkarị ndị a bụ ndị ọrịa nwere nsogbu pụtara oke na oke oke, yana ndị na-adịghị aulinụ insulin site na inje.

Mana ọ dịkwa mkpa icheta na Formin pliva nwere akụkụ na-adịghị mma. Ọ contraindicated na nke a:

• mgbe onye ọrịa nwere ketoacidosis mamịrị ma ọ bụ nke shuga,
• enwere ike mgbe onye ọrịa na-arịa ọrịa dị iche iche na-efe efe ma ọ bụ ịwa ahụ, n'ihi nke a kpatara ya na insulin insulin.
• contraindication gunyere nsogbu doro anya na ọrụ nke obi, yana nsonaazụ niile nke ọrịa nke anụ arụ a.
• ekwesịghị ị notụ ọgwụ n’oge ịtụrụ ime ma ọ bụ n’oge nwanyị na-enye nwa ara,
• na N'ezie, mgbe enwere nnabata nke ihe ndị mejupụtara ọgwụ ahụ.

Nyocha nke ọtụtụ ndị ọrịa na-egosi na ọ dị mkpa ịgbaso nri pụrụ iche mgbe ị na-eji ọgwụ a.

Ọ kwesịrị ịbụ opekata mpe kalori ma mee ka ọrịa ahụ nwee ike iwute ya dị mma. Ọ bụ ndị ọkachamara niile kwuru ihe a.

Kedu ihe bụ analogues na ụgwọ ha?

Dịka ọgwụ ọ bụla ọzọ, Formin Pliva nwere analogues nke ya. Ọnụahịa ha dabere na ụlọ ọrụ ndị nrụpụta, ya bụ, mba nke emere ọgwụ ndị a. Ọ bụrụ na anyị na-ekwu maka eziokwu ahụ bụ na nke a bụ onye na-ahụ maka ọgwụgwọ mba ụwa, mgbe ahụ ọnụ ahịa ya, n'otu n'otu, ga-adị elu karịa ugboro atọ karịa nke onye Russia.

N'ọnọdụ ọ bụla, tupu ịmalite ọgwụgwọ maka ọrịa ahụ na-akpata, ịkwesịrị ịkpọtụrụ dọkịta gị mgbe niile. Ikwesiri ichota nsogbu ya puru iche site na otu ogwu, yana ihe contraindications diri maka iji ya. Ọ dị mkpa iji nyocha zuru ezu ma naanị mgbe ịmalite ọgwụgwọ ahụ gasịrị na Formin Pliva, ntuziaka maka iji ọgwụ ahụ kọwaa ihe n'ọnọdụ iji ọgwụ ahụ, yana ụdị ọnụọgụ ọgwụ.

Oge ụfọdụ na mmalite ọgwụgwọ site na nri diges, ụfọdụ ahụ erughị ala nwere ike ime. Nke a na-egosipụta onwe ya n'ụdị ọgbụgbọ ma ọ bụ vomiting. O nwekwara ike belata agụụ ma ọ bụ ihe ụtọ dị ụtọ n'ọnụ.

Patientsfọdụ ndị ọrịa na-ekwu na ọnya na-arịa ọrịa shuga. N'ezie, ọ bụrụ na ị drinkụọ ọgwụ ahụ na oke oke oke, mgbe ahụ, ahụike ahụike jọgburu onwe ya nwere ike ịda.

Ọ bụrụ na anyị na-ekwu maka nke analogues bụ ndị kasị ewu ewu taa, mgbe ahụ, dịka ọmụmaatụ, ọtụtụ ndị dọkịta nwere ike ịkọpụta Bagomet, ọnụ ahịa ya na-amalite site na 130 wee ruo 220 rubles kwa ngwungwu, dabere na ọnụ ọgụgụ mbadamba dị na ya. Ihe a na-ekwu na-emetụtakwa ịta nke ihe bụ isi, dịka ọmụmaatụ, ngwugwu nke 60 sits nke 850 mg na-eme atụmatụ na 220 rubles, mana ọnụ ọgụgụ nke mbadamba 1000 mg ugbua na-efu obere karịa narị rubles anọ.

Enwekwara analog dika Glycon. Ọnụ ahịa ya dabakwara na ntinye uche nke ihe bụ isi na ọnụọgụ mbadamba. O sitere na 115 ruo 280 rubles. Mba nke mebere ọgwụ ndị a, dị ka nke gara aga, bụ Argentina.

Mana otu ọ dị etu ahụ, ịkwesighi ịgbanwe ọgwụ nke dọkịta gị gwara gị, ọ bụghị naanị imerụ ahụ ike gị.

Vidiyo dị n’isiokwu a kọwara etu esi ewere Formin na ọgwụ ndị ọzọ.

Mlọ ọgwụ

Mgbe nchịkwa gasịrị, a na-etinye obi gị dum site na eriri afọ. Bioavailability nwere ike iru 60%. A na-ahụta ndọta kachasị plasma mgbe awa 2 gachara.

EGO! Ntinye na nri na-ebelata ọgwụ ịgwụ kachasị na 40%, ọgwụgwọ zuru oke na-apụta mgbe nkeji iri atọ na ise gachara.

Ọ na - agbakọ na sel ọbara, ọ dịghị agbanye na protein plasma. A na-ahụ mkpokọta na akwara, akwara na akụrụ akwara yana ke gland.

Iwepu ọkara ndụ bụ awa 6.5.

A na-eji ya maka ụdị ọrịa shuga nke 2, nke e ji amata ọnọdụ ketoacidotic. Ndabere maka nhọpụta ọgwụ bụ enweghị ike nke nri.

Nsonaazụ

• eriri afọ: mmeghachi omume dyspeptik (ọgbụgbọ, vomiting, obi mgbawa, afọ mgbu), afọ ọsịsa, flatulence, agụụ,
• Usoro endocrine: iwetulata glucose di ala,
• metabolism: lactic acidosis, ụkọ vitamin B₁₂,
• sistem hematopoietic: megaloblastic ụdị anaemia,
• anụ ahụ: rashes, itching.

Dodoụbiga ya ókè

• ọgbụgbọ
• vomiting
• afọ ọsịsa
• ibelata na ahụ ọkụ
• mgbu afọ
• myalgia
• iku ume ngwa ngwa
• anya ntughari
• ọnwụ nke mmụọ
• mmepe nke coma.

Usoro ọgwụgwọ gụnyere:

• mkpochapu nke ndị na - ahụ ike hypoglycemic,
• ime ụlọ ọgwụ,
• ịba ọcha n'anya
• ọgwụgwọ symptomatic.

Mkparịta ụka ọgwụ ọjọọ

Mmepe nke mmetụta dị iche iche ga-ekwe omume site na iji ya ọzọ Usoro na ụzọ ndị ọzọ. Yabụ:

• Ngwurugwu sulfonylurea (Butamide, Glibenclamide), salicylates (Aspirin, Salicylamide), acarbose, mgbochi na - egbochi steroidal (Nimesil, Ketorol), ndị na - egbochi monoaminoxygenase (Selegiline, Nialamide), oxytetracycline azolefin cyclopenne cyne cynelopente cyne (Anaprilin, Concor) na - akwalite mmụba shuga nke ihe bụ isi.
• glucocorticosteroids (Beclomethasone, Methylprednisolone), mgbochi mkpịsị ọnụ (Regulon, Novinet), glucagon, homonụ thyroid (Thyroxine, thyroidin), thiazide (Indapamide, Chlortiazidium, Efuroteminazidazum, Furoseminazurouro, Aminazine), nicotinic acid (Cordiamin, Acipimox) nwere ike belata mmetụta hypoglycemic,
• nifedipine na-abawanye nnabata, na ihe kachasị n'ime plasma, na-egbochi ntụpọ nke ihe arụ ọrụ,
• cimetidine na-agbadata njem nke metformin, nke a na-ebute oke nsogbu nke lactic acidosis,
• ọgwụ cationic (Digoxin, Morphine, Vancomycin) na iji ogologo oge nwere ike ịbawanye ọdịnaya nke Metformin n'ọbara site na 60%,
• anticoagulants na-akụda omume nke ndị ikpeazụ,
• ayodiin nwere ihe ndi ozo di iche n’enye aka na mkpokoro ihe di n’ime Phoin na ntinye lactic acidosis.

Ntụziaka pụrụ iche

Ke ọgwụgwọ ọgwụ kwesịrị:

• ijikwa ọrụ akụrụ
• ịchọpụta ụbara nke lactate na plasma ọbara ugboro abụọ n’afọ,
• lelee nnabata glucose ma jikọta ya na insulin, ọgwụ nke sulfonylurea.

EGO! Nnukwu ọgwụgwọ ịwa ahụ dị ukwuu, mmerụ ahụ, nnukwu mpaghara ọkụ, ọrịa na-efe efe na mkpali nke na-ebili na oke ịrị elu - ihe a niile bụ ihe ngosipụta maka iwepụ Formin ya na nhọpụta nke insulin ọzọ.

N'ikuku na nká

Ọ ga-ekwe omume ịdebe ndị mmadụ karịa afọ 65 n'okpuru nlekọta anya, na-eburu n'uche nyocha nke ike ọgwụgwọ na mmetụta ọjọọ. Achọrọ ndị ọrịa a ka ha chọpụta ikpochapụ creatinine tupu ịmalite usoro ọgwụgwọ (ụkpụrụ creatinine ọbara abụghị ihe a tụkwasịrị obi maka ịtụle ọrụ akụrụ).

Tụnyere ihe analogues

Ọgwụ ndị a nwere usoro ọgwụ ọgwụ yiri nke a:

1. Vipidia. Ihe nọ n'ọrụ bụ alogliptin. Ọ na - emetụta njikọ nke insulin na pancreas, bioavailability ruru 100%. Amachibidoro iji ụdị ọrịa shuga 1 ọrịa mellitus. Jiri mkpachapụ anya na ọnụnọ nke pancreatitis, yana insulin na sulfonylureas. Dosebọchị kwa ụbọchị bụ 25 mg. Anakwere n'agbanyeghị nri, na-enweghị ita, na-enweghị mmiri ọ .ụ .ụ. Onweghi mmekorita ya na ogwu ndi ozo achoputara.
2. Glibenclamide. Ihe bụ isi bụ glibenclamide. Ọ bụ ihe na - akpali akpali nke insulin njikọta site na sel Langerhans. Ọ na - eme ka mmetụta nke akụkụ anụ ahụ dị na insulin, na - enyere aka belata lipoproteins, nwere mmetụta antithrombotic. Ebe ọ bụ na akwara amịkọrọ akwara, akwara akwara gbawara ya. Ọ na-ejikọ protein na nchekwa nke ọma. Emebere ogwu a n’otu n’otu dabere ogo usoro ịrịa ọrịa shuga yana afọ onye ọrịa.
3. Miglitol. Na-egbochi enzyme alfa-glucosidase na epithelium nke obere eriri afọ. Ọ na - egbochi mmebi nke polysaccharides na glucose, na - ebelata ịmịcha ya. Ihe fọrọ nke nta ka ọ bụrụ na ọ dịghị ihe jikọrọ ya na protein protein, excretion akụrụ na-agbanweghị Amachibidoro ọgwụ a maka iji ọnya afọ, ọnụnọ nke hernias buru ibu. Ekwesịrị iji ya ma ọ bụ mgbe nri gasịrị.
4. Avandia Ihe na-arụ ọrụ bụ rosiglitazone. Ọ na - eme ka mmetụta nke adipose anụ ahụ nwee insulin, akwara ọkpụkpụ, akwara umeji. Ọ na - akpali metabolism, na - ebelata mkpụkọ glucose, insulin, acids fatty acids nke dị n'ọbara. Ọ na-ejikọ protein na ọbara n'ọtụtụ dị elu, nke na-esiteghi na ntinye ọgwụ na afọ onye ọrịa. Ewepula ya na ụmụ akụrụ. A na - eji ya na insulin. Contraindicated na nnukwu akwara ọbara ọrịa, obi nkụda mmụọ. A na-anabata nnabata n'agbanyeghị nri nri.
5. Starlix. Ihe bụ isi bụ nateglinide. Ọ na - enyere aka weghachite n’oge insulin mepụta ya, mụbaa ọkwa ya n’ime nkeji iri na ise mbụ ka nri gachara, n’ihi na ọ na - eme ka glucose na - apụta. A na-egosi nnabata ọkara ọkara tupu nri ugboro atọ n'ụbọchị. Jiri mkpachapụ anya na nsogbu nsogbu akwara na akụrụ. Enwere ike iji ya mee ihe dị ka monotherapy.

Ludmila: “Achọtara onye ikwu m ọrịa shuga afọ ole na ole gara aga. Kemgbe ahụ, ọ nọ na-anara ọgwụ, otu n’ime ya bụ Mkpụrụ osisi. Na mbu, shuga ruru 18. Mgbe ọgwụgwọ bidoro. Ọkpụkpụ enyere aka? Eeh, a na-ahụkwa ya nke ọma. Onye ikwu na-a allụ ọgwụ niile dịka enyere ha n’iwu, ọ naghịzi atụ ụjọ ịchọpụta ihe ndị na-egosi glucose ha. Ọ kwụsiri ike n'ogo nke 5-6. "

Olga: “Nne nne m nwere ọrịa shuga.Amaara m na agaghị m enweta nke a, ebe ọ bụ na ịdị arọ na shuga dị mgbe niile. Ma n’oge ime nke abụọ, a chọpụtara ọrịa shuga, bụ́ nke a mụpụtara nwa ka ọ bụrụ nke nkịtị. Onye endocrinologist dere m Formin. Ọmarịcha ọgwụ na-enyere aka igbochi shuga. ”

Mpempe akwụkwọ bụ ihe nnweta antidiedi, arụmọrụ nke ọtụtụ ndị ọrịa chọpụtara. Ọ dịghị mkpa iji mezuo nchịkwa nnwere onwe ya, ebe ọ bụ na enwere ọtụtụ contraindications. Tupu ojiji, ị ga-agakwuru onye ọkachamara ga-enwe ike nyochaa ihe ọghọm na nsonaazụ ọgwụgwọ niile a tụrụ anya ya.