Aspirin ma ọ bụ acetylsalicylic acid

Acetylsalicylic acid bụ otu aspirin? Ndi odi iche di iche n’etiti ogwu abuo? Aspirin na acetylsalicylic acid na-arụ otu ọrụ, ma a na-eji ya na mpaghara ọgwụ dị ka cardiology, ọgwụgwọ, ịwa ahụ. Aspirin bu aha ahia acetylsalicylic acid.

Mbadamba ọgwụ aspirin so na ọgwụ ọgwụ mgbochi mkpali, ọgwụ na - arụ ọrụ n'ime ya bụ acetylsalicylic acid. Ọ dị n'ụdị mbadamba, nke nwere ihe ruru 500 mg nke ihe arụ ọrụ, yana stachi ọka na microcrystalline cellulose. N'ụzọ bụ isi, a na-eji ọgwụ a eme ihe dị ka ọgwụ eji egbu anụ yana ọgwụ na-egbu egbu.

Tablets were mbadamba nkume ndị a ọnụ, na usoro nke 300 mg ruo 1 g, na-ebelata ihe mgbu, na-ewepụ ihe mgbu na akwara na nkwonkwo, na-emekwa ka ị nwee ike belata ọnụnọ nke ọnya dị nro, dịka ọmụmaatụ, oyi ma ọ bụ flu. A na-eji otu doses ahụ eme ka ahụ dị ala.

Njirimara nke ọgwụ a na-ahapụ ya ka ejiri ya mee ihe na nnukwu ọrịa ọrịa, ebe a na-eji doses dị elu karịa ka ọ dị na mbụ.

A nwekwara ike iji ọgwụ ahụ gbochie ịmalite ọbara ọgbụgba, nke a na-enweta site na ịkwụsịlata usoro platelet.

Mgbe ị na-a theụ ọgwụ ahụ, enwere contraindications ndị a:

Amachibidoro iji ọgwụ a n'ihu ọnụnọ nke nfụkasị ahụ ma ihe ndị nọ n'ọrụ n'onwe ya yana ihe ndị mejupụtara ya. Na mgbakwunye, a naghị atụ aro ka ọ cribeụọ ọgwụ a maka ojiji n'ihu ọnụnọ nke ọbara ọgbụgba.

Ihe ndi a bu ndi anakpo contraindications:

  • nhazi nke anticoagulants,
  • Enzyme cytosolic ezughi oke,
  • Ọrịa ụkwara ume ọkụ,
  • ọrụ ezughi oke,
  • ọnụnọ nke ọrịa na-adịghị ala ala nke afọ na duodenum,
  • ọrịa shuga mellitus
  • gout
  • n'okpuru afọ 12
  • tụụrụ ime
  • inye ara.

Na ọnụnọ nke opekempe contraindications, a ga-ewere ọgwụ naanị mgbe ikike nke dọkịta na-abịa.

Ngosipụta nke mmetụta ndị ọzọ nwere ike ime n'ụdị mmeghachi omume hypersensitivity n'ụdị rashes na anụ ahụ, yana mbelata ọkwa platelet n'ọbara yana ihe mgbu na afọ. Manifestzọ ọ bụla n’ime ngosipụta ha chọrọ ka nnabata dọkịta nọ ebe ahụ kwụsị ịbata ma gwọọ ya ozugbo.

Ceptionmata aspirin, dị ka ntụziaka a si dị, a na-eme ya mgbe nri gachara, yana ị drinkingụ ọtụtụ mmiri mmiri. Ikike njikwa onwe gị na enweghị ndụmọdụ na dọkịta gị nwere ụbọchị ise. N'ime otu usoro, a na-enye ya ego site na 300 mg ruo 1 g, na enwere ike ịnweta nchịkwa ugboro ugboro mgbe awa 4-8 gachara. Usoro kachasị elu ụbọchị niile bụ 4g.

Acetylsalicylic acid

Ogwu a di na ulo ogwu ogwu nke otutu ezinulo.

Aha mbụ banyere acetylsalicylic acid malitere na ngwụcha narị afọ nke 19, yana aha ya bụ Felix Hoffman na-eto eto, onye bụ onye ọrụ nke ụlọ ọrụ ọgwụ na Bayer. Isi okwu ya bụ imepụta ọgwụgwọ ga - enyere nna ya aka ime ka mgbu ghara iburu ya na nkwonkwo ikpere ya. Nke a bụ nhọpụta nke sodium salicylate onye ọrịa. Naanị ihe ndọghachi azụ ya bụ enweghị ike iwere ya, n'ihi eziokwu ahụ ọgwụ kpatara oke iwe nke mucosa gastric.

Afọ abụọ ka e mesịrị, enwetara patent maka ọgwụ a na-akpọ aspirin na Berlin, ebe acetylsalicylic acid mere dị ka ihe na-arụ ọrụ.

Ọgwụ ahụ nwere ọgwụ mgbochi mkpali, ọgwụ nyocha na nsonaazụ ọgwụ, ma, n'otu oge ahụ, na-egbochi usoro nchịkọta platelet.

Ngosiputa puru iche maka eji

Ekwesịrị ịkpachara anya mgbe a na-edegara ndị ọrịa nwere ọrịa imeju na akụrụ, ụkwara ume ọkụ, ọnya afọ na ọbara ọgbụgba, ọbara ọgbụgba ma ọ bụ usoro ọgwụgwọ iji mee ka ụkọ ọbara dị n'ọbara, mebie obi obi na-adịghị ala ala.

Jiri na obere doses nwere ike jiri nwayọ uric acid excretion, nke na-akpata ọgụ nke gout na ndị ọrịa na-ebutekarị ọrịa a. Ọ bụrụ na ọ dị mkpa, ka ogologo oge were dọkịta gị na-elele ya mgbe niile ma nyochaa ọkwa nke haemoglobin.
5-7bọchị 5-7 tupu ịwa ahụ na n’oge nnabata, a ga-akwụsị ị medicationụ ọgwụ otu a.
Ejiri ọgwụ. A na-eji ọgwụ ndị otu a mee ihe maka angina pectoris, nnukwu ihe mgbu nke nkụchi obi, ọrịa obi.

Nsonaazụ

Ogologo oge nwere ike ibute nsogbu akwara nke etiti dịka ọgbụgbọ, tinnitus, na nkwarụ anya. Enwere ike ibukwu oge oge ọbara ọgbụgba, ọrụ akụrụngwa na-arụ ọrụ nke ọma, yana nnukwu akụrụ. Ekwesịrị ịkpachara anya mgbe ị na-a theụ ọgwụ ahụ na ụmụ nwanyị dị ime.

Ọ bụ otu ihe ka ọ bụ otu?

Enwere ọdịiche dị n'etiti ọgwụ abụọ a? Ọ bụrụ n ’ịmatakwu ndụmọdụ nke ọgwụ abụọ a, ọ na-enyo na naanị ihe dị iche bụ usoro onunu ogwu. Aspirin dị na usoro onunu ogwu nke 100, 300 na 500 mg. A na - eme Acetylsalicylic acid n'ụdị mbadamba, usoro nke ya bụ 250 na 500 mg.

Mlọ ọgwụ

Mmetụta analgesic bụ n'ihi usoro etiti na nke etiti. N'ihe banyere ọnọdụ febrile, ọ na-ebelata okpomọkụ site na ime ihe na etiti thermoregulation.

Ọgbakọ na nnabata plateletka thrombosis mbelata n'ihi ikike nke ASA igbochi njikọ nke thromboxane A2 (TXA 2) na platelet. Na-egbochi njikọ prothrombin (coagulation factor II) na imeju na - na usoro karịrị 6 g / ụbọchị. - emewanye PTV.

Mlọ ọgwụ

Orhapụ ọgwụ ahụ mgbe ị theụsịrị ọgwụ n'ime ya fọrọ obere. Oge ọkara nke ASA na-agbanweghị bụ ihe na-erughị nkeji iri abụọ. TCmax ASA na - nkeji 10-20, salicylate na - esite na - site na 0.3 ruo awa 2.0.

Ihe dị ka 80% nke plasma bound ala acetylsalicylic na salicylic acid. Ihe ndị dị ndụ na-adịgide ọbụna mgbe ihe ahụ dị n'ụdị protein.

Metabolized na imeju. Ọ bụ ya mere akụrụ. Mmetụta obi na - emetụta pH mmamịrị: mgbe ọ gbanyere acid acid, ọ na-ebelata, ma mgbe alkrax na-abawanye.

Ngw’oru ogwu a na-acho n’usoro ogwu a were. Kpochapu ihe ahu n’echeputaghi. Ọzọkwa, na ụmụ nke afọ 1 nke ndụ, ma e jiri ya tụnyere ndị okenye, ọ ga-eji nwayọ nwayọ karịa.

Ihe ngbanwe

Mbanye ASA bụ contraindicated na:

  • Aspirin ashma,
  • n'oge iwe ọnya na ọnya ọnya nke ọwara nri,
  • ọbara afọ / afọ na-agba ọbara,
  • ụkọ vitamin K,
  • hemophilia, hypoprothrombinemia, hemorrhagic diathesis,
  • Enweghi ike G6PD
  • ọbara mgbali portal,
  • ọdịda akụrụ / imeju
  • mgbasa aortic
  • n'oge ọgwụgwọ (ọ bụrụ na ọgwụ ọgwụ kwa izu karịrị 15 / mg),
  • akwara ogbu na nkwonkwo, gout,
  • (ọnwa atọ mbụ na nke ikpeazụ bụ ezigbo contraindications),
  • hypersensitivity na ASA / salicylates.

Ojiji nke ASA na cosmetology

Ihe mkpuchi ihu Acetylsalicylic acid na-enye gị ohere iwepu mbufụt, belata ọzịza nke anụ ahụ, wepu ncha ọbara, wepu elu ala nke mkpụrụ ndụ nwụrụ anwụ na pores ndị dị ọcha.

Ọgwụ a na-agbaze anụ ahụ nke ọma ma nwee abụba nke ukwuu na abụba, nke na-eme ka ọ dị mma maka iji ya maka ọgwụgwọ ya ihe otutu: mbadamba mmiri jupụtara na mmiri, etinyere ihe ndị na-acha ọkụ na ihu ma ọ bụ tinye ya na ngwakọta nke ihe mkpuchi ihu.

Acetylsalicylic acid si ihe otutu na-arụ ọrụ nke ọma na mgbakwunye na ihe ọ juiceụ lemonụ lemon ma ọ bụ mmanụ a honeyụ. Ọ dị irè iji dozie nsogbu akpụkpọ ahụ na iji ụrọ kpuchie ya.

Iji kwadebe ihe mkpuchi lemon-aspirin, mbadamba (6 iberibe) bụ nanị ihe a juiceụ na-ete ya mmiri ruo mgbe a ga-enweta otu uka. Mgbe ahuta ogwu ghari gbarie umere wee hapụrụ ha ruo mgbe ọkpọọ.

A kwadebere ihe mkpuchi na mmanụ a asụ dị ka ndị a: mbadamba (3 iberibe) na-ete mmiri, wee mechaa, mgbe ha gbazere, gwakọtara ya na mmanụ a 0.5ụ 0.5-1 (tii).

Iji kwadebe nkpuchi ụrọ, mbadamba 6 nke ASA na ngaji abụọ (teaspoon) nke ụrọ ọcha / acha anụnụ anụnụ ga-agwakọta na mmiri ọkụ.

Dodoụbiga ya ókè

Dodoụbiga mmanya ókè nwere ike isi na:

  • ọgwụgwọ ogologo oge nke ASA,
  • otu nchịkwa ọgwụ dị oke oke.

Ihe ịrịba ama nke ịdoụbiga ihe ókè bụ ọrịa salicylism, ịrịa ọrịa ịba ọcha n'anya, ọbara mgbali, tinnitus, ọgbụgbọ, ọgbụgbọ.

Ike sonyere mmasi, nzuzu, akpịrị ịkpọ nkụ, ngụ na-abụghị cardiogenic, mmebi nke CBS, ujo.

N'ihe banyere ịAụbiga ọgwụ ókè nke ASA, onye ahụ kwesịrị ịga ụlọ ọgwụ ozugbo. A na-asa afọ ya, nye ya, nke CBS nyocha.

Dabere na ọnọdụ nke WWTP na nguzozi nke mmiri na electrolytes, enwere ike ịkọwa ụzọ mbido nke ngwọta, sodium citrate na sodium bicarbonate (dika infusion).

Ọ bụrụ na pH mmamịrị bụ 7.5-8.0, na plasma ịta nke salicylates karịrị 300 mg / l (na nwatakịrị) na 500 mg / l (na okenye), a chọrọ nlekọta siri ike. alkaline diuretics.

Site n'ị carriedụbiga mmanya ókè, meghachikwaa mmiri mmiri, gwọọ ọgwụgwọ symptomatic.

Mmekorita

Ọ na - eme ya egbu egbu mgbochi usoro,acid acid, methotrexatensonaazụ nke ndị na - egbu mmụọ hypoglycemic ọgwụ ọjọọ, ọgwụ sulfa.

Mmetụta adịghị ike diuretics (-gbapụta potassium na loopback), ọgwụ antihypertensive Ihe mgbochi ACEndị nnọchi anya uricosuric.

Iji nke imekotaotuugbo iji ọgwụ antithrombotic, thrombolytics,anticoagulants na-apụtaghị ìhè na - eme ka ọbara ọgbụgba dịkwuo elu.

GCS welie mmetụta uto nke ASA na mucous akpụkpọ ahụ nke ọwara nri, mee ka nwepu ya ma belata ịta plasma.

Mgbe ejiri nnu mee ihe n'otu oge, Li na-eme ka plasma nke Li + ion dịkwuo elu.

Na-eme ka utị mmanya na-egbu belata mucosa nke ọwara mmiri.

Ntụziaka pụrụ iche

Ekwesịrị iji ọgwụ ahụ mee ihe na-akpachara anya na ndị nwere ya pathologies nke akụrụ na umeji, ịba ụba ọbara ọgbụgba, ọnya na-akụ ngụgụ obi, n'oge ọgwụgwọ anticoagulants, yana ndị mmadụọnya ọnya na ọnya afọ na / ma ọ bụ ọbara ọgbụgba / eriri afọ.

Ọbụna na obere doses, ASA na-ebelata excretion. uric acidna na ọrịa ọrịa nwere ike ime ka nnukwu ọgụ gout.

Mgbe ị na-a highụ ọgwụ oke elu nke ASA ma ọ bụ mkpa ịgwọ ọgwụ ogologo oge, ọ dị mkpa iji nyochaa ọkwa ahụ mgbe niile ma hụ dọkịta.

Dịka onye na - egbochi ọgwụ mgbochi, ojiji nke ASA na ọgwụ nke 5-8 g / ụbọchị. a kpaara oke na oke ihe ọghọm nke akwara ozi si na eriri afọ.

Iji belata ọbara ọgbụgba n'oge ịwa ahụ yana oge ọrụ, ịnwe salicylates na-akwụsị ụbọchị 5-7 tupu ịwa ahụ.

Mgbe ị na-ewere ASA, a ga-echetarịrị na enwere ike ị drugụ ọgwụ a ihe na-erughị ụbọchị asaa na-enweghị ịgakwuru dọkịta. Dịka ọgwụ antipyretic ASA, a na-ahapụ ya ị drinkụ ihe karịrị ụbọchị 3.

Chemical Njirimara nke umi

Mgbe mkpu mkpu ASA, agịga enweghị agba ma ọ bụ polyhedra monoclinic nwere uto dịtụ mma. Ihe kristal ndị a kwụsiri ike na ikuku akọrọ, mana na-enwekwu iru mmiri, ha na-eji nwayọ nwayọ gaa salicylic na acetic acid.

Ihe dị n ’ụdị ya dị ọcha bụ ntụ ntụ na-acha aja aja nke agba ọcha na enweghị isi. Ọdịdị isi nke acetic acid bụ ihe na-egosi na ihe ahụ malitere ịmalite hydrolyze.

malitere ịrịa , ebe ọ bụ na ngwakọta dị otú a nwere ike ibute mmepe nke ọnọdụ na-eyi ndụ nwata egwu - Ọrịa Reye.

N'ime ụmụ amụrụ ọhụrụ, acid salicylic nwere ike ịchụpụ n'ihi albumin bilirubin na mmepe mmepe encephalopathy.

ASA na-abanye n’ime mmiri na akwara niile, gụnyere mkpụrụ mmiri, synovial na peritoneal fluid.

Na ọnụnọ nke edema na mbufụt, itinye mkpụrụ ndụ nke salicylate n’ime oghere nkwonkwo na-agbadata. Na ogbo nke mbufụt, n'ụzọ dị iche, ọ na-eji nwayọ nwayọ.

Jiri n’oge ime na inye nwa ara

A na - egbochi Acetylsalicylic acid n'oge ime. Karịsịa n’ime ọnwa atọ mbụ na nke ikpeazụ. N'oge mmalite, ị theụ ọgwụ ahụ nwere ike ịbawanye n'ihe ize ndụ nke nsogbu ịmụ nwa, na usoro nke ikpeazụ - imeru afọ ime na imebi ọrụ.

ASA na metabolites ya na obere ihe banye n’ime mmiri ara ehi. Mgbe nchịkwa ọgwụ na-akpachaghị anya, achọpụtaghị nsonaazụ n'akụkụ ụmụ ọhụrụ; yabụ, dịka iwu, ọ dịghị mkpa ịkwụsịtụ inye nwa (HB).

Ọ bụrụ na egosiri nwanyị ogologo oge na oke ọnụọgụ nke ASA, ọ dị mkpa ịkwụsị ịba ọcha n'anya B.

Ntụziaka maka ojiji:

Acetylsalicylic acid bụ ọgwụ nwere ọgwụ mgbochi mkpali, antipyretic, analgesic na antiaggregant (belata uto platelet).

Ọ bụ otu ihe ahụ

Aspirin na acetylsalicylic acid bụ otu ọgwụ. A nabata ụdị azụmahịa aha - aspirin, na ụwa niile, mana aha analogues, kemịkal kemịkal nke salicylic acid na ntụgharị zuru ụwa ọnụ - ihe dịka 400 (anopyrine, aspilite, apo-asa, wdg). A na-achọta Salicylates n'ụgbụgbọ willow, nke ejirila na ọgwụ ndị mmadụ na-agwọ ahụ ọkụ, gout, na ihe mgbu mgbu.

A na-atụle ya Nke ọgwụ 1 maka isi ọwụwa yana oke ahụ. Ọzọkwa, acetylsalicylic acid nwere mmetụta mgbochi mkpali, na-egbochi mmepụta nke prostaglandins - ndị ọrụ mgbasa ozi nke usoro mkpali ahụ.

Mmetụta antipyretic nke acid a sitere na ikike ya igbochi ọrụ nke ụbụrụ na-edozi thermoregulation. Mgbe ọnọdụ okpomọkụ dị oke ma na-emerụ ahụ ahụ, ọgwụ ahụ ngwa ngwa na ọtụtụ awa "kụọ" ya na ụkpụrụ nkịtị.

Echiche nke ndị dọkịta

Dmitry Vladimirovich, dọkịta na-awa ahụ. “Ọgwụ dị irè ma dị ọnụ ala maka igbochi nkụchi obi. Ana m akwado mbadamba mkpụrụ osisi na-etinye ume iji belata ihe ọjọọ na-akpata mucosa gastric. ”

Konstantin Vitalievich, onye na-amụ banyere ọrịa na-ekwu, sị: “Ọgwụ ahụ anabatabeghị mmetụta dị mma banyere oyi, nkwụsị akara na syndromes mgbu. Site n'iji ogologo oge, ị nwere ike nweta ọnya afọ, nnukwu ihe egwu ọbara ọgbụgba site na ngwara.

Sergey Alexandrovich, dibia ophthalmologist: “A pụrụ ịkpọ ọgwụ aspirin ọgwụ nke narị afọ, nke nwere abamuru ya na mmetụta ya. Gaghị a itụ ya were were, na-eche na ọ bụ ihe gbasara vitamin. A na-emegharị ya n'ọnọdụ ndị nwere nsogbu gbasara akụrụngwa yana ọrịa ịba ọcha n'anya. ”

Nyocha Ndidi na Aspirin na Acetylsalicylic Acid

Denis, gbara afọ 25Rostov: “p Asụ Ọgwụ Aspirin aghọrọla m ọgwụ ọgwụ na-adịghị mkpa, n'oge ọdịda, m na-ejikarị oyi na-ejikarị ya na ọgwụ mgbochi mkpali. Ahụtụbeghị m mmetụta dị iche iche nke ọgwụ. ”

Irina Fedorovna, onye dị afọ 43, Ryazan: “Acetylka bụ ọgwụgwọ ochie, nke egosipụtara, ọ na-adigide mgbe niile. Ozugbo m chere na m arịa ọrịa, ana m eme ya dị ka nna m: ana m ewere mbadamba 2 n'abalị na n'ụtụtụ dị ka ọhụụ. "

Natalya, onye dị afọ 30, Tula: “Ọgwụ a mara mma, ugboro ole ọ nyeere oyi aka! Nne nne m na-a itụ ya na mgbu na akwara na nkwonkwo, ọ na-ekwu, na-enyere aka. Naanị ihe bụ na ndị inyom dị ime enweghị ike iji ya n’oge nke 1 na nke atọ, yana n’oge nsọ. Ihe mkpuchi aspirin na-ehicha ma na-eme ka akpụkpọ ahụ dị nro.

P Asụ Ọgwụ Aspirin na ihe mejupụtara ya

Dabere na nhazi ọkwa ọgwụ a na-anabatakarị, aspirin nwere nkewa dị ka ọgwụ mgbochi mkpali, onye na-ahụ maka nyocha nke nwere ụdị ọrụ dị iche iche. Na mgbakwunye na ịme ihe na isi mgbu, a na-eji ọgwụ a gbochie usoro obi.

Dị mgbapụta nke Aspirin dị iche iche. A na-ahụ ọgwụ ahụ n'ụdị nke soluble yana mbadamba ụrọ. N'agbanyeghị ụdị mgbapụta, isi ihe na-arụ ọrụ nke Aspirin bụ acetylsalicylic acid, nke na-ahụ maka ihe bụ ọgwụ ọgwụ bụ isi.

N'otu oge, anụ ahụ na-arụ ọrụ na-aracha ahụ kpamkpam site na eriri afọ. N'ihi ọrụ nke imeju na ihe nke enzyme ya, a na-agbanye acetylsalicylic acid ka ọ bụrụ metabolite bụ isi. Ọ bụ omume ya na-enyere aka belata okpomọkụ ma ọ bụ belata ihe mgbu. Site na ọrụ nhazi nke akụkụ ahụ niile, a na-ewepụ ihe ahụ kpam kpam n'ime ụbọchị atọ.

Na nkà mmụta ọgwụ ọgbara ọhụrụ, a na-enweta acetylsalicylic acid site na mmekorita nke salicylic na sulfuric acid na acetic anhydride. A na-agwakọta kristal ndị na-esite na stachi ma nweta ọgwụ a maara nke ọma.

Omume ọgwụ

Ọgwụ na-ebelata ihe mgbu, ahụ ọkụ na mbufụtna-egbochi nsogbu.

Otu ọgwụ ọgwụ: NSAIDs.

Pharmacodynamics na pharmacokinetics

Acetylsalicylic acid - gịnị ka ọ bụ?

Acetylsalicylic acid bụ salicylic ester nke acetic (ethanoic) acid.

Usoro nke acetylsalicylic acid bụ (ASA) - C₉H₈O₄.

Koodu OKPD 24.42.13.142 (acetylsalicylic acid gwakọtara na ọgwụ ndị ọzọ).

Inweta ASA

N'ime mmepụta ASA, a na-eji usoro esterification na ethanoic acid mee ihe.

Mlọ ọgwụ

Mmetụta analgesic bụ n'ihi usoro etiti na nke etiti. N'ihe banyere ọnọdụ febrile, ọ na-ebelata okpomọkụ site na ime ihe na etiti thermoregulation.

Ọgbakọ na nnabata plateletka thrombosis mbelata n'ihi ikike nke ASA igbochi njikọ nke thromboxane A2 (TXA 2) na platelet. Na-egbochi njikọ prothrombin (coagulation factor II) na imeju na - na usoro karịrị 6 g / ụbọchị. - emewanye PTV.

Mlọ ọgwụ

Orhapụ ọgwụ ahụ mgbe ị theụsịrị ọgwụ n'ime ya fọrọ obere. Oge ọkara nke ASA na-agbanweghị bụ ihe na-erughị nkeji iri abụọ. TCmax ASA na - nkeji 10-20, salicylate na - esite na - site na 0.3 ruo awa 2.0.

Ihe dị ka 80% nke plasma bound ala acetylsalicylic na salicylic acid. Ihe ndị dị ndụ na-adịgide ọbụna mgbe ihe ahụ dị n'ụdị protein.

Metabolized na imeju. Ọ bụ ya mere akụrụ. Mmetụta obi na - emetụta pH mmamịrị: mgbe ọ gbanyere acid acid, ọ na-ebelata, ma mgbe alkrax na-abawanye.

Ngw’oru ogwu a na-acho n’usoro ogwu a were. Kpochapu ihe ahu n’echeputaghi. Ọzọkwa, na ụmụ nke afọ 1 nke ndụ, ma e jiri ya tụnyere ndị okenye, ọ ga-eji nwayọ nwayọ karịa.

Ihe ngosiputa eji eme ihe: gini kpatara mbadamba acetylsalicylic acid na enyere aka?

Ihe ngosiputa maka iji acetylsalicylic acid bu:

  • ọrịa febrile na ọrịa na-efe efe,
  • ọrịa ogbu na nkwonkwo,
  • rheumatism,
  • ọnya mgbu myocardiummere site na mmeghachi omume immunopathological,
  • mgbu mgbu sitere na ọnọdụ dị iche iche, gụnyere eze mgbu (gụnyere isi ọwụwa metụtara ọrịa nkwụsị mmanya), nkwonkwo na mgbu mgbu, neuralgia, migraine,algomenorrhea.

Ọzọkwa aspirin (ma ọ bụ acetylsalicylic acid) ka eji mee ihe prophylactic ma ọ bụrụ egwu thrombosis,thromboembolism, MI (mgbe enyere ọgwụ ọgwụ maka mgbochi nke abụọ).

Ihe ngbanwe

Mbanye ASA bụ contraindicated na:

  • Aspirin ashma,
  • n'oge iwe ọnya na ọnya ọnya nke ọwara nri,
  • ọbara afọ / afọ na-agba ọbara,
  • ụkọ vitamin K,
  • hemophilia, hypoprothrombinemia, hemorrhagic diathesis,
  • Enweghi ike G6PD
  • ọbara mgbali portal,
  • ọdịda akụrụ / imeju
  • mgbasa aortic
  • n'oge ọgwụgwọ (ọ bụrụ na ọgwụ ọgwụ kwa izu karịrị 15 / mg),
  • akwara ogbu na nkwonkwo, gout,
  • (ọnwa atọ mbụ na nke ikpeazụ bụ ezigbo contraindications),
  • hypersensitivity na ASA / salicylates.

Nsonaazụ

Mmetụta ọghọm nke ọgwụgwọ ASA nwere ike ime n'ụdị:

Site n'iji ogologo oge, tinnitus na-apụta, ọnụnụ na-ebelata, anya anaghị arụ ọrụ, ọgbụgbọ na-eme, na, na ọnya ọwụwa, isi ọwụwa. Ọbara dịkwa mma. hypocoagulationvomiting bronchospasm.

Acetylsalicylic acid, ntuziaka maka ojiji (Usoro na usoro onunu ogwu)

Na rheumatism nọ n'ọrụ Edere ndị okenye okenye site na 5 ruo 8 g nke ASA kwa ụbọchị. Maka nwatakiri, a na-agbakọ dose ahụ dabere na ibu. Dịka iwu, ọ dị iche na 100 ruo 125 mg / kg / ụbọchị. Otutu eji eme ihe - 4-5 p.

Izu 1-2 mgbe ebidochara usoro ahụ, a na-ebelata ọgwụ nwatakịrị ahụ ruo 60-70 mg / kg / ụbọchị, maka ndị ọrịa toro eto, usoro onunu ogwu ahụ ka bụ otu. Gaa n'ihu ọgwụgwọ ruo izu isii.

Dika ntuziaka maka iji acetylsalicylic acid, ekwesiri ịkwụsị ọgwụ ahụ nwayọ nwayọ karịa oge izu 1-2.

Acetylsalicylic acid maka isi ọwụwa dịka edepụtara maka ọnọdụ okpomọkụ ka etinyere ya na usoro ọnụọgụ dị ala. Yabụ, na mgbu mgbu na Ọnọdụ febrile udiri maka 1 dose maka onye okenye - site na 0.25 ruo 1 g na otutu nke ngwa sitere na 4 ruo 6 rubles kwa ụbọchị.

Ekwesịrị icheta na n'ọnọdụ isi ọwụwa, ASA na-arụ ọrụ kachasị ma ọ bụrụ na iwe na-akpata iwe site na mmụba na ICP (nrụgide intracranial).

Maka ụmụaka, ọgwụ kachasị mma n'otu oge bụ 10-15 mg / kg. Otutu nke ngwa - 5 p / ụbọchị.

Ọgwụgwọ agaghị adị karịa izu abụọ.

Maka ịdọ aka na ntị thrombosis na embolism ASA were 2-3 p / ụbọchị. 0,5 g nke ọ bụla. Iji meziwanye ihe ndị dị na rheological (maka ịgba), a na-a drugụ ọgwụ ahụ ogologo oge na 0.15-0.25 g / ụbọchị.

Maka nwatakịrị gbara afọ ise, otu usoro ị doụ ọgwụ bụ 0.25 g, a na-ahapụ ụmụaka dị afọ anọ inye 0.2 g nke ASA otu ugboro, ụmụaka dị afọ abụọ - 0.1 g, na otu afọ - 0.05 g.

Amachibidoro ịnye ụmụaka ụmụaka ASA site na ọnọdụ okpomọkụ na-ebilite n'okirikiri malitere ịrịa. Ọgwụ a na-arụ na otu ụbụrụ na akwara akụkụ dịka ụfọdụ nje, yana yana malitere ịrịa nwere ike kpasu mmepe n’ime nwataỌrịa Reye.

Ojiji nke ASA na cosmetology

Ihe mkpuchi ihu Acetylsalicylic acid na-enye gị ohere iwepu mbufụt, belata ọzịza nke anụ ahụ, wepu ncha ọbara, wepu elu ala nke mkpụrụ ndụ nwụrụ anwụ na pores ndị dị ọcha.

Ọgwụ a na-agbaze anụ ahụ nke ọma ma nwee abụba nke ukwuu na abụba, nke na-eme ka ọ dị mma maka iji ya maka ọgwụgwọ ya ihe otutu: mbadamba mmiri jupụtara na mmiri, etinyere ihe ndị na-acha ọkụ na ihu ma ọ bụ tinye ya na ngwakọta nke ihe mkpuchi ihu.

Acetylsalicylic acid si ihe otutu na-arụ ọrụ nke ọma na mgbakwunye na ihe ọ juiceụ lemonụ lemon ma ọ bụ mmanụ a honeyụ.Ọ dị irè iji dozie nsogbu akpụkpọ ahụ na iji ụrọ kpuchie ya.

Iji kwadebe ihe mkpuchi lemon-aspirin, mbadamba (6 iberibe) bụ nanị ihe a juiceụ na-ete ya mmiri ruo mgbe a ga-enweta otu uka. Mgbe ahuta ogwu ghari gbarie umere wee hapụrụ ha ruo mgbe ọkpọọ.

A kwadebere ihe mkpuchi na mmanụ a asụ dị ka ndị a: mbadamba (3 iberibe) na-ete mmiri, wee mechaa, mgbe ha gbazere, gwakọtara ya na mmanụ a 0.5ụ 0.5-1 (tii).

Iji kwadebe nkpuchi ụrọ, mbadamba 6 nke ASA na ngaji abụọ (teaspoon) nke ụrọ ọcha / acha anụnụ anụnụ ga-agwakọta na mmiri ọkụ.

Dodoụbiga ya ókè

Dodoụbiga mmanya ókè nwere ike isi na:

  • ọgwụgwọ ogologo oge nke ASA,
  • otu nchịkwa ọgwụ dị oke oke.

Ihe ịrịba ama nke ịdoụbiga ihe ókè bụ ọrịa salicylism, ịrịa ọrịa ịba ọcha n'anya, ọbara mgbali, tinnitus, ọgbụgbọ, ọgbụgbọ.

Ike sonyere mmasi, nzuzu, akpịrị ịkpọ nkụ, ngụ na-abụghị cardiogenic, mmebi nke CBS, ujo.

N'ihe banyere ịAụbiga ọgwụ ókè nke ASA, onye ahụ kwesịrị ịga ụlọ ọgwụ ozugbo. A na-asa afọ ya, nye ya, nke CBS nyocha.

Dabere na ọnọdụ nke WWTP na nguzozi nke mmiri na electrolytes, enwere ike ịkọwa ụzọ mbido nke ngwọta, sodium citrate na sodium bicarbonate (dika infusion).

Ọ bụrụ na pH mmamịrị bụ 7.5-8.0, na plasma ịta nke salicylates karịrị 300 mg / l (na nwatakịrị) na 500 mg / l (na okenye), a chọrọ nlekọta siri ike. alkaline diuretics.

Site n'ị carriedụbiga mmanya ókè, meghachikwaa mmiri mmiri, gwọọ ọgwụgwọ symptomatic.

Mmekorita

Ọ na - eme ya egbu egbu mgbochi usoro,acid acid, methotrexatensonaazụ nke ndị na - egbu mmụọ hypoglycemic ọgwụ ọjọọ, ọgwụ sulfa.

Mmetụta adịghị ike diuretics (-gbapụta potassium na loopback), ọgwụ antihypertensive Ihe mgbochi ACEndị nnọchi anya uricosuric.

Iji nke imekotaotuugbo iji ọgwụ antithrombotic, thrombolytics,anticoagulants na-apụtaghị ìhè na - eme ka ọbara ọgbụgba dịkwuo elu.

GCS welie mmetụta uto nke ASA na mucous akpụkpọ ahụ nke ọwara nri, mee ka nwepu ya ma belata ịta plasma.

Mgbe ejiri nnu mee ihe n'otu oge, Li na-eme ka plasma nke Li + ion dịkwuo elu.

Na-eme ka utị mmanya na-egbu belata mucosa nke ọwara mmiri.

Usoro ahia

OTC ogwu.

Ntụziaka na Latin (sample):

Rp: Acidi acetylsalicylici 0,5
D. t. d. N 10 na tab.
Mbadamba mbadamba S. 1 / ụbọchị 3 mgbe ị risịrị nri, na-a plentyụ nnukwu mmiri.

Ọnọdụ nchekwa

Mbadamba kwesịrị ịchekwa ya n’ebe kpọrọ nkụ na mgbe okpomọkụ dị n'okpuru 25 Celsius.

Exbọchị mmebi

Ntụziaka pụrụ iche

Ekwesịrị iji ọgwụ ahụ mee ihe na-akpachara anya na ndị nwere ya pathologies nke akụrụ na umeji, ịba ụba ọbara ọgbụgba, ọnya na-akụ ngụgụ obi, n'oge ọgwụgwọ anticoagulants, yana ndị mmadụọnya ọnya na ọnya afọ na / ma ọ bụ ọbara ọgbụgba / eriri afọ.

Ọbụna na obere doses, ASA na-ebelata excretion. uric acidna na ọrịa ọrịa nwere ike ime ka nnukwu ọgụ gout.

Mgbe ị na-a highụ ọgwụ oke elu nke ASA ma ọ bụ mkpa ịgwọ ọgwụ ogologo oge, ọ dị mkpa iji nyochaa ọkwa ahụ mgbe niile ma hụ dọkịta.

Dịka onye na - egbochi ọgwụ mgbochi, ojiji nke ASA na ọgwụ nke 5-8 g / ụbọchị. a kpaara oke na oke ihe ọghọm nke akwara ozi si na eriri afọ.

Iji belata ọbara ọgbụgba n'oge ịwa ahụ yana oge ọrụ, ịnwe salicylates na-akwụsị ụbọchị 5-7 tupu ịwa ahụ.

Mgbe ị na-ewere ASA, a ga-echetarịrị na enwere ike ị drugụ ọgwụ a ihe na-erughị ụbọchị asaa na-enweghị ịgakwuru dọkịta. Dịka ọgwụ antipyretic ASA, a na-ahapụ ya ị drinkụ ihe karịrị ụbọchị 3.

Chemical Njirimara nke umi

Mgbe mkpu mkpu ASA, agịga enweghị agba ma ọ bụ polyhedra monoclinic nwere uto dịtụ mma. Ihe kristal ndị a kwụsiri ike na ikuku akọrọ, mana na-enwekwu iru mmiri, ha na-eji nwayọ nwayọ gaa salicylic na acetic acid.

Ihe dị n ’ụdị ya dị ọcha bụ ntụ ntụ na-acha aja aja nke agba ọcha na enweghị isi. Ọdịdị isi nke acetic acid bụ ihe na-egosi na ihe ahụ malitere ịmalite hydrolyze.

malitere ịrịa , ebe ọ bụ na ngwakọta dị otú a nwere ike ibute mmepe nke ọnọdụ na-eyi ndụ nwata egwu - Ọrịa Reye.

N'ime ụmụ amụrụ ọhụrụ, acid salicylic nwere ike ịchụpụ n'ihi albumin bilirubin na mmepe mmepe encephalopathy.

ASA na-abanye n’ime mmiri na akwara niile, gụnyere mkpụrụ mmiri, synovial na peritoneal fluid.

Na ọnụnọ nke edema na mbufụt, itinye mkpụrụ ndụ nke salicylate n’ime oghere nkwonkwo na-agbadata. Na ogbo nke mbufụt, n'ụzọ dị iche, ọ na-eji nwayọ nwayọ.

Acetylsalicylic acid na mmanya

Acoụrụma na-egbu egbu n'oge ASA. Njikọ dị otú ahụ nwere ike ibute ọnya afọ na eriri afọ, yana oke mmeghachi azụ.

Gịnị bụ acetylsalicylic acid maka mmanya ogbugbu?

ASA bu ezigbo ogwu eji agwo oria nke oma, nihi ogwugwu ogwu aru.

Agbanyeghị, ekwesiri icheta na ị theụ ọgwụ ahụ ka ịghara ị alcoholụ mmanya na-egbu egbu, mana ihe dị ka awa 2 tupu oriri ahụ. Nke a na-ebelata ihe egwu dị na agụmakwụkwọ. microthrombi na obere arịa ụbụrụ na - na akụkụ - edema anụ ahụ.

Jiri n’oge ime na inye nwa ara

A na - egbochi Acetylsalicylic acid n'oge ime. Karịsịa n’ime ọnwa atọ mbụ na nke ikpeazụ. N'oge mmalite, ị theụ ọgwụ ahụ nwere ike ịbawanye n'ihe ize ndụ nke nsogbu ịmụ nwa, na usoro nke ikpeazụ - imeru afọ ime na imebi ọrụ.

ASA na metabolites ya na obere ihe banye n’ime mmiri ara ehi. Mgbe nchịkwa ọgwụ na-akpachaghị anya, achọpụtaghị nsonaazụ n'akụkụ ụmụ ọhụrụ; yabụ, dịka iwu, ọ dịghị mkpa ịkwụsịtụ inye nwa (HB).

Ọ bụrụ na egosiri nwanyị ogologo oge na oke ọnụọgụ nke ASA, ọ dị mkpa ịkwụsị ịba ọcha n'anya B.

Ntụziaka maka ojiji:

Acetylsalicylic acid bụ ọgwụ nwere ọgwụ mgbochi mkpali, antipyretic, analgesic na antiaggregant (belata uto platelet).

Omume ọgwụ

Usoro nke acetylsalicylic acid bụ n'ihi ikike ya igbochi njikọ nke prostaglandins, nke na-arụ nnukwu ọrụ na mmepe nke usoro mkpali, ahụ ọkụ na mgbu.

Mbelata nke ọnụ ọgụgụ nke prostaglandins dị n'etiti etiti thermoregulation na-eduga na vasodilation na mmụba na sweating, nke na-eduga na mmetụta antipyretic nke ọgwụ. Na mgbakwunye, iji acetylsalicylic acid nwere ike belata mmetụta nke akwara na-ebuso ndị mgbasa ozi mgbu mgbu site na ibelata mmetụta nke prostaglandins na ha. Mgbe etinyere ya, enwere ike ịtụle mkpokọta acetylsalicylic acid nke dị na ọbara mgbe nkeji 10-20 gachara, wee guzobe ya ka ọ bụrụ ihe ndị na-eme ka salicylate metabolites gasịrị awa 0.3-2. Acetylsalicylic acid weputara site na akụrụ, ọkara ndụ ahụ bụ nkeji 20, ọkara ndụ maka salicylate bụ awa 2.

Ihe ngosi maka iji acetylsalicylic acid

Acetylsalicylic acid, ihe egosipụtara maka ihe aka ya, ka enyere n'iwu:

  • ajọ ọrịa rheumatic fever, pericarditis (mbufụt nke oghere azụ nke obi), rheumatoid ogbu na nkwonkwo (mbibi anụ ahụ na obere arịa), rheumatic chorea (nke e gosipụtara site na nkwonkwo akwara nke akwara), ọrịa Dressler (njikọ nke pericarditis na mkpali ma ọ bụ oyi baa),
  • ọrịa mgbu nke ịdị nwayọ ruo obere oge: migraine, isi ọwụwa, eze mgbu, mgbu n'oge oge obia, osteoarthritis, neuralgia, mgbu na nkwonkwo, akwara,
  • ọrịa nke spain tinyere mgbu: sciatica, lumbago, osteochondrosis,
  • ọrịa febrile
  • ọ dị mkpa ịhapụ ịnabata ọgwụ mgbochi mkpali na ndị ọrịa nwere “aspirin triad” (nchikota ụkwara ume ọkụ, imi nke imi na nnagide acetylsalicylic acid) ma ọ bụ aspirin,
  • mgbochi nke infarction myocardial na ọrịa obi obi ma ọ bụ mgbochi mgbochi nlọghachi,
  • ọnụnọ nke ihe ndị dị ize ndụ maka ischemia myocardial myocardial na-enweghị mgbu, ọrịa obi obi, ọrịa angina na-akwụghị chịm,
  • prophylaxis nke thromboembolism (ijigide arịa nwere thrombus), ọrịa nje na-arịa mital valve valvular, mitral valve prolapse (dysfunction), atrial fibrillation (ọnwụ nke ike akwara nke atria na-arụ ọrụ synchronously),
  • nnukwu thrombophlebitis (mbufụt nke akwara akwara na otite nke thrombus na-egbochi lumen na ya), infarction pulmonary (ihe mgbochi nke arịa na-ebute ngụgụ), ụkwara ume ọkụ na-adịkarị ala.

Ntuziaka maka iji acetylsalicylic acid

Mbadamba acid a na-akpọ Acetylsalicylic bụ nke eji eme ya, ọ na-atụ aro ị toụchaa mmiri ara ehi, mmiri nkịtị ma ọ bụ alkaline.

Maka ndị okenye, a na-atụ aro acetylsalicylic acid ka ọ bụrụ mbadamba 3-4 kwa ụbọchị, mbadamba 1-2 (500-1000 mg), yana oke 6 kwa ụbọchị (3 g). Ogologo oge eji acetylsalicylic acid bụ ụbọchị 14.

Iji mee ka ihe ndị metụtara ọbara dị mma, yana onye na-egbochi platelet na-agbakwunye, a na-edenye mbadamba ụrọ nke acetylsalicylic acid kwa ụbọchị ọtụtụ ọnwa. Site na infarction myocardial yana maka mgbochi nke infarction myocardial nke abụọ, nkuzi maka acetylsalicylic acid na-atụ aro iwe 250 mg kwa ụbọchị. Ọrịa ụbụrụ na-agbanwe agbanwe na mkpụrụ nke ụbụrụ thromboembolism na-atụ aro iwere ½ mbido acetylsalicylic acid na-eji nwayọ were dozie ya ka ọ bụrụ mbadamba 2 kwa ụbọchị.

Edebere Acetylsalicylic acid nye ụmụaka n'ime usoro ọgwụgwọ ndị a: okenye karịa afọ 2 - 100 mg, afọ atọ - 150 mg, afọ anọ - 200 mg, karịa afọ 5 - 250 mg. A na-atụ aro ka ụmụaka jiri Acetylsalicylic acid ugboro 3-4 n'ụbọchị.

Ngwakọta ọgwụ aspirin na Acetylsalicylic Acid

Ngwakọta dị n'ọrụ nke nkwadebe abụọ bụ acetylsalicylic acid (salcarlic acetic acid ester) na usoro nke 500 mg / 1 tab. Dabere na akụrụngwa ọgwụ, a na-akpọ ya ihe na - abụghị ọgwụ steroid a na - ahọpụtaghị maka mmiri ọgwụ mgbochi.

Ihe omume ogwu a dabere na mgbochi nke otu ụdị cyclooxygenases abụọ (ụdị 1 na 2). Mbelata nke ahụ ọkụ na ahụ efe nke ihe mgbu (nkwonkwo, akwara na isi ọwụwa) n'ọnọdụ ọnọdụ febrile jikọtara ya na mgbochi nke njikọta COX-2. COX-1 na - ekere òkè na ịkpụpụta prostaglandins, yabụ, mwepu nke njikọta ya na - akpata nsonaazụ metụtara cytoprotection anụ ahụ. Ma n'otu oge acetylsalicylic acid gbochiri njikọ nke thrombooxygenase.

Ihe ngosiputa maka iji Aspirin (ma obu ASA) bu ihe mgbochi nke thrombosis na oria embolism, ebe enwere mbelata na nsogbu medicardial infarction na ischemic stroke.

Eliekwado ọnọdụ ndị ọrịa nwere ọrịa varicose veins mgbe ha na-ewere ASA mekwara na njikọta nke njikọta nke thromboxanes na mkpochapu otu n'ime ihe na-akpata mgbasawanye akwara - ịchapu ọbara (na-eme ka viscosity ya na ọchịchọ nke ịmepụta mkpụkọ ọbara).

Usoro onunu ogwu

Iwu nke ị "ụ "Aspirin" na acetylsalicylic acid bụ otu ihe, ọ dabere na isi ihe eji eme ya, yana njiri mara ahụike mmadụ. Ọ bụla ọkachamara ga-akwado na usoro ị ofụ ọgwụ ọjọọ ahụ bụ kpamkpam nke onwe ya.Agbanyeghị, na ọgwụ, ọ bụ omenala iji ọtụtụ usoro ụwa niile:

  1. Iji wepu ọrịa mgbu na okenye (ihe karịrị afọ 15), a na-eji otu mbadamba (500 ma ọ bụ 1000 mg). Oge dị n'etiti doses kwesịrị dịkarịa ala 4, ma usoro ahụ ga-adịru ihe karịrị ụbọchị 5.
  2. Ọ bụrụ na mmadụ kwesịrị ibelata ahụ ọkụ, mgbe ahụ, a na-enye ọgwụ ahụ ihe ruru ụbọchị 3. Iji mepụta nsonaazụ achọrọ, a na-eji mmiri dị ukwuu theụọ ọgwụ ahụ.
  3. Maka mgbochi nke usoro obi na ọrịa na-efe efe, a na-ede mbadamba mbadamba otu ụbọchị ma ọ bụ ụbọchị ọ bụla. Ọ bụ dibia bekee gara kpebie oge ihe ọ ga-eme.

Ndị dọkịta na-atụ aro ị theụ ọgwụ ahụ mgbe nri gasịrị. Nke a na - eme ka a banye n'ọrụ ahụ ma nwee mmetụta ọgwụgwọ dị mma, na - enweghị mmerụ ahụ mucosa. Ọ bụ ekwesighi ị presụ ọgwụ maka onwe gị; ịmịcha ọbara dị ize ndụ.

Ntụnyere Ọgwụ

Aspirin ma ọ bụ acetylsalicylic acid, nke ka mma? Ọ gaghị ekwe omume ịchọta azịza doro anya nke ajụjụ a. Na isi, ọgwụ ndị a dịgasị iche n'ụdị ntọhapụ na usoro nke ihe bụ isi na-arụ ọrụ.

Ọgwụ ndị ahụ bụ otu ihe mejupụtara, ihe ngosi maka ojiji nke Aspirin na acetylsalicylic acid bụ otu, nke na-eme ka ọgwụ ndị ahụ nwee ike ịgbanwe. Isi ihe dị iche n'etiti ọgwụ ndị ahụ bụ ọnụahịa, nke dabere na onye nrụpụta, usoro nke acid na mbadamba na ụdị ntọhapụ. Acetylsalicylic acid, dị ka a na-achị, na-ere ntakịrị dị ọnụ ala karịa Aspirin yiri.

Ọ bụrụ na mmadụ anabataghị ọgwụ ndị dị na Aspirin, mgbe ahụ ị takingụ acetylsalicylic acid bụkwa maka ya. Agbanyeghị, ọgwụ ọgwụ ugbu a nwere ụdị analogues dị iche iche, nke dị na ihe ha nwere ike dochie ọrụ nke salicylic acid.

Analogs nke "Aspirin" na acetylsalicylic acid:

  1. Citramon
  2. "Paracetamol".
  3. "Egithromb" (nke ka nke analogues ndị ọzọ dị oke ọnụ).
  4. Movalis (nke yiri ọnụ na Egithromb).

Na nkezi, ọnụahịa nke Aspirin dịgasị site na 70 rubles ruo 500 rubles.

Agbakwunye na-adọrọ mmasị

Ndị ọkachamara na-atụ aro ịgbaso iwu ụfọdụ nke ga-echebe ahụ dịka o kwere mee, na -ebelata ịdị irè nke ọgwụ:

  1. Ọ bụrụ na mbupute mbadamba ihe mbụ, ihe ọ ga-eme ga-eme ngwa ngwa.
  2. Ọ dị mkpa iji chekwaa mucosa gastric site na ọrụ nke acetylsalicylic acid. A na-ewere mbadamba ihe naanị mgbe nri gasịrị.
  3. Cheta ịbawanye ọbara ọgbụgba, nke na-egbochi ị theụ Ọrịa Aspirin tupu ịwa ahụ, ọbụna tupu ị gaa na dọkịta ezé. A na-ahapụ ọgwụ ahụ iji otu izu tupu ịwa ahụ.
  4. Ọgwụ a na-ebelata oke uric acid, nke dịkwa mkpa ịtụle yana njiri ahụike mmadụ.

Compgbaso ntuziaka dọkịta kwesiri ekwesi ga - enyere aka zere usoro ndị na - adịghị mma n'ahụ, na -ebelata arụmọrụ ọgwụ niile.

Ozi ndi ozo

Dịka ntuziaka ahụ si dị, ekwesighi ịchekwa acetylsalicylic acid ebe ikuku ikuku nwere ike ịrị elu karịa 25 Celsius. N'ebe akọrọ na n ’ụlọ okpomọkụ, ọgwụ ahụ ga-adabara afọ 4.

Ngwaahịa ọgwụ kachasị ewu ewu, aspirin, ghọrọ onye a ma ama nye ndị ọrụ nke ụlọ ọrụ ọgwụ Bayer, bụ onye na 1893 mepụtara teknụzụ maka mmepụta ọgwụ a. Ezubere aha ahia ahu bu "Aspirin" na akwukwo nke "A" (acetyl) na "Spiraea" - aha osisi meadowsweet na Latin. Mkpụrụ ọgwụ na-arụ ọrụ, acetylsalicylic acid, bụ nke mbụ kewapụrụ site na ihe ọkụkụ a.

Ọgwụ kachasị ewu ewu, aspirin, abụrụla ekele a ma ama nye ụlọ ọrụ ọgwụ Bayer.

Ngwongwo Aspirin

Na ọgwụ, osisi willow bụ ama ama dị ka ihe dị irè nke na-enyere aka belata okpomọkụ.Agbanyeghị, ọgwụ ndị dabere na ya butere nsonaazụ na-adịghị mma, bụ nke gosipụtara onwe ha na ọgbụgbọ na mgbu na-enweghị ike ịbịakwute oghere dị n'ime afọ.

Acetylsalicylic acid (ASA) - aha ọzọ maka Aspirin - bụ nke mbụ nwetara site na osisi willow na mmalite narị afọ nke 19. Ka ọ na-erula n'etiti narị afọ, achọpụtara usoro kemịkal nke salicylic acid. Na nke mbụ, ndị ọrụ Bayer natara samples nke ghọrọ ihe dabara adaba maka ọgwụike. Companylọ ọrụ a malitere ire ọgwụ ọgwụ n'okpuru aha aha ya bụ Aspirin.

N'oge na-adịghị anya, ụlọ ọrụ ndị ọzọ nwekwara ikike nke ịre ọgwụ ahụ, nke kwere ka ọgwụ ahụ rute na shelves nke ụlọ ahịa ọgwụ ụwa niile.

Acetylsalicylic acid, ma ọ bụ Acidum acetylsalicylicum (aha Latin Aspirin), bụ naanị ọgwụ n'oge ahụ nke nwere otu ọgwụ ọgwụ na - abụghị steroidal nke nwere mmetụta mgbochi mkpali. Ọgwụ bụ ezigbo ihe na-akpata ọgwụ. Site n'enyemaka ya, ọnụ ọgụgụ ndị nwụrụ n'ọrịa belatara nke ukwuu, na mgbe achọpụtara ike Aspirin iguzogide mkpụkọ ọbara na arịa ọbara, ndị mmadụ nwere ohere ibi ndụ dị mma mgbe ha nwesịrị nkụchi obi, ọrịa strok, wdg.

Acetylsalicylic acid (aha nke abụọ bụ Aspirin) n'ezie nwere ihe pụrụ iche. Na 70s, ekpughere ya na ọ nwere ike ịkwụsị ọrụ nke prostogladins. N'ihi ihe onwunwe a, Aspirin na-ekpochapụ mbufụt n'ihi nsonaazụ na usoro ndị a na-eme na ya.

Mmetụta analgesic na mkpochapu ọkụ bụ n'ihi nrụpu nke mpaghara ụbụrụ na-ahụ maka nghọta nke ihe mgbu na thermoregulation.

Ihe ngosi ozo maka ojiji bu mmanu intracranial na mgbu na isi. Site na nhazi nke Aspirin, usoro ịba ọcha n'anya nke ọbara, yana oghere dị na arịa ndị ahụ na-abawanye ụba, nke na-egbochi mmepe nke nkụchi obi, ọrịa strok na ndị ọrịa nwere ebumnuche ọbara.

Acetic acid salicylic ester (dịka a na-akpọ Aspirin n'ụzọ ọzọ) ka a na-eji ya eme ihe kwa ụbọchị. Otu mbadamba ga-eme ka ọnọdụ ahụ dị mma mgbe mmanya na-egbu egbu. Karịsịa maka nke a, ịkwesịrị ịzụta ọgwụ Alka-Seltzer ma ọ bụ Aspirin UPSA (aha ọgwụ maka mmanya ogbugbu, nke nwere acetylsalicylic acid).

Ọ dị mma ịmara na, dịka nnyocha ndị a mere na Mahadum Oxford, usoro Aspirin ga-esi belata ihe ize ndụ nke ịmalite oncology na mammary gland, prostate, esophagus, ngụ na akpịrị.

Ọ ga-ekwe omume iji acetylsalicylic acid (aha Aspirin) n’onweghị, yana yana ọgwụ ndị ọzọ. Taa, enwere ọtụtụ ego n'ime ya - Citramon, Askofen, Asfen, Coficil, Acelisin. Were ọgwụ ahụ naanị yana yana ọgwụ ndị ọzọ.

Pụ Ọgwụ Aspirin n'ihi oyi

P Asụ Ọgwụ Aspirin, ma ọ bụ acetylsalicylic acid, bụ ọgwụ na - akwụsị ngwa ngwa ọbụladị ihe mgbu kachasị njọ sitere na ọnọdụ dị iche iche ma na - emetụta oke elekwasị anya. Na mgbakwunye na akụrụngwa ndị a, a na-enye ọgwụ a ka ọ dị oke mkpa maka ndị mmadụ na-enwekarị ọbara ọgbụgba na akwara vaskụla. A na-ejikarị ọgwụ aspirin maka oyi, ebe ọ bụ na ọ nwere ike iwepụ ahụ ọkụ, na -ebelata ngwa ngwa na-egosi okpomọkụ.

N'ime usoro dos ọ dị mkpa iji acetylsalicylic acid maka oyi, enwere ọgwụ mgbochi ọ bụla maka iji, anyị na-amụtakwu.

Hụrụ mmejọ? Họrọ ya wee pịa Ctrl + Tinye

  • Gini bu ogwu “Aspirin”
  • Etu esi a drinkụ ọgwụ
  • Kedu ọgwụ a ga-eji maka ahụ ọkụ
  • Gịnị bụ ihe nnọchianya ọbara

Acid enyemaka

Ọ bụghị onye ọ bụla maara na isi ihe dị na ọgwụ a bụ salicylic acid, nke zoro ezo na ahịhịa pụrụ iche nke a na-akpọ siprea, nke na-akọwa n'ezie ihe omume aha a ma ama bụ "Aspirin".A na-achọta ihe yiri ya n'ọtụtụ osisi ndị ọzọ, dị ka ube, jasmine ma ọ bụ willow, nke ejiri ya rụọ ọrụ na Egypt oge ochie ma kọwaa ya dị ka ọgwụ siri ike site n'aka Hippocrates.

Ọgwụgwọ ọgwụgwọ

Mgbe iwere acetylsalicylic acid n’ime ahụ, hyperemia na-agbadata, ikike a na-ahụkarị na saịtị nke mbufụt na - ebelata - ihe a niile na - eduga n'ịhụpụta analgesic na mgbochi mkpali. Ọgwụ na-abanye n’arụ na mmiri niile, ịmịkọrọ na-abanye n’arụ na imeju.

Ihe nke acetylsalicylic acid:

  • na-enye ọgwụ mgbochi mkpagbu kwa ọnwa 24–48 mgbe mmalite ọgwụ,
  • na-ewepu mgbu dị nfe na agafeghị oke.
  • na-eme ka ahụ mmadụ dị elu, ma gharakwa ịrụ ọrụ ọ bụla.
  • acetylsalicylic acid na-agbaze ọbara, na-akpaghasị nchịkọta platelet - ibu dị na akwara obi na-ebelata, ohere nke nkụchi obi na-ebelata.

Enwere ike ị drugụ ọgwụ ahụ iji gbochie thrombosis, ọrịa strok, belata ihe ize ndụ nke nsogbu mgbasa na ụbụrụ.

Attentionaa ntị! A na-ahụ mmetụta antiplatelet nke ASA n'ime ụbọchị 7 mgbe ị aụ otu ọgwụ ọgwụ. Ya mere, ọgwụ agaghị a beụbiga mmanya tupu ịwa ahụ.

Jiri ọgwụ Acetylsalicylic acid na-egbochi (inhibits) mgbe niile ịkpụbe mkpụkọ ọbara (mkpụkọ ọbara), nke nwere ike igbochi oghere nke akwara. Nke a na - egbochi ihe nkụchi obi.

N'ihi oke ọrụ ya, a na-eji acetylsalicylic acid maka ọgwụgwọ na mgbochi nke ọrịa dị iche iche etiologies n'ime ndị okenye na ụmụaka karịa afọ 15.

Kedu ihe na - enyere aka acetylsalicylic acid:

  • Ọnọdụ febrile na-eso pathologies nke ọrịa na-efe efe,
  • rheumatism, ogbu na nkwonkwo, pericarditis,
  • migraine, eze mgbu, akwara, nkwonkwo, mgbu nke nwanyị, neuralgia,
  • mgbochi nke nkụchi obi, ọrịa strok na nsogbu ọbara, viscosity ọbara na-arịwanye elu,
  • mgbochi ọbara egbochi mkpụkọ na mkpụrụ ndụ ihe nketa nye thrombophlebitis,
  • enweghi ike angina pectoris.

A na-etinye ASA na usoro ọgwụgwọ dị mgbagwoju anya na ọgwụgwọ nke oyi baa, pleurisy, osteochondrosis, lumbago, ntụpọ obi, prolapse mitral valve. A na-atụ aro ka eji ọgwụ a mee ihe mgbe ihe ịrịba ama mbụ nke flu, ọrịa nkịtị na-ahụkarị - ọ na-eme ka ọsụsọ na-aba ụba, nke na-eduga n'ịbawanye ngwa ngwa n'ọnọdụ ahụ.

Ndụmọdụ! P Asụ Ọgwụ Aspirin bụ otu n'ime usoro ọgwụgwọ kachasị mma maka iwepu nsonaazụ nke mmanya; ọgwụ ahụ na-agbaze ọbara, na-ewepụ isi ọwụwa na ọria, ma na-ebelata nrụgide intracranial.

Acetylsalicylic acid maka isi ọwụwa bụ ihe a na-akpọ aspirin ma ọ bụ ọgwụ plọg ebe niile maka isi. Ọ bụ mgbochi mkpali na antipyretic.

O kwere omume ị asụ ọgwụ aspirin maka ụmụ nwanyị dị ime na ndị na-enye nwa ara, ụmụaka

A na - egbochi Acetylsalicylic acid na ụmụaka na - erubeghị afọ 14, ebe ọgwụ a nwere ike ịdakwasị bilirubin, nke nwere ike ibute encephalopathy na ụmụ ọhụrụ, ajọ akụrụ na hepatic ọrịa na ụmụaka ụlọ akwụkwọ ọta akara na ụmụaka. Usoro onunu ogwu umuaka bu 250 mg ugboro abuo, ubochi kwesiri ekwesi bu ubochi 750.

A machibidoro Acetylsalicylic acid n’oge amachibidoro ime n’oge ọnwa atọ nke mbụ - ọgwụ nwere mmetụta teratogenic, nwere ike kpalite mmepe nke ntụpọ obi nke nwatakịrị, kewara nke okpo ugwu.

Attentionaa ntị! ASA na - ebute ime ọpụpụ na mbido mmalite.

Ọ gaghị ekwe omume ị acụ acetylsalicylic acid, paracetamol ọbụna na ọkara trimester atọ - ọgwụ ahụ na - akpata ọbara mgbali elu n'ime nwa ebu n'afọ, nke na - ebute mmepe nke pathologies na okporo ụzọ, na - egbochi ọbara ọgbụgba.Iji ASA n'oge a nwere ike ibute ọbara ọgbụgba.

N'oge ị na-a breastụ ara, ị gaghị a ASụ ASA, ebe ọ bụ na acid na-abanye n'ime mmiri ara ehi ahụ, nke nwere ike ibute ahụike nwata, mmepe nke mmeghachi ahụ nfụkasị ahụ siri ike.

N'ime usoro nke oge nke abụọ, nnabata ga-ekwe omume, mana naanị ma ọ bụrụ na enwere akara dị nkọ yana iji nnabata dọkịta, amachibidoro nnabata ahụ na oge ikpeazu nke ịmụ nwa.

Ntuziaka maka iji acetylsalicylic acid

A ga-ewere ASA naanị mgbe ị risịrị nri, ka ị ghara ịkpasu mmebi ahụ na sistem, ị nwere ike jiri mmiri na-a gasụ ya na mmiri. Usoro ọkọlọtọ bụ 1-2 mbadamba 1-2 ugboro abụọ kwa ụbọchị, mana ọ bụghị ihe karịrị 1000 mg n'otu oge. Gaghị a drinkụ ihe karịrị mbadamba 6 kwa ụbọchị.

Otu esi ewere ASA maka ụfọdụ ọrịa:

  1. Maka ịmịcha ọbara, dị ka prophylactic megide nkụchi obi - 250 mg kwa ụbọchị maka ọnwa 2-3. N'ọnọdụ mberede, a na-anabata mmụba ọgwụ ruru 750 mg.
  2. Acetylsalicylic acid sitere na isi ọwụwa - o zuru ezu iji 250-500 mg nke ASA, ọ bụrụ na ọ dị mkpa, ịnwere ike ikwugharị ọgwụ ahụ mgbe awa 4-5 gachara.
  3. Site na oria, oyi, site na okpomọkụ, mgbu mgbu - 500-1000 mg nke ọgwụ ahụ kwa awa 4, mana ọ nweghị ihe karịrị mbadamba 6 kwa ụbọchị.
  4. Iji kpochapụ ihe mgbu n’oge nsọ - 250ụọ 250-500 mg nke ASA, ọ bụrụ na ọ dị mkpa, megharịa mgbe awa 8-10 gachara.

Ndụmọdụ! Na-a Asụ ọgwụ Aspirin na ntakịrị mmụba na usoro olu, ma ọ bụrụ na enweghị ọgwụ ndị na-egbochi mmiri ọkụ.

A bit nke akụkọ ihe mere eme

Acetylsalicylic acid bu ụzọ chọpụta na ngwụsị narị afọ nke 19 site n'aka onye na-eto eto ọgwụ kemikal Felix Hoffman, onye rụrụ ọrụ na Bayer n'oge ahụ. Ọchọrọ n'ezie iwepụta ngwaọrụ ga-enyere nna ya aka belata nkwonkwo mgbu. Echiche nke ebe ịchọrọ maka ihe ndị achọrọ, dọkịta nna ya kpaliri ya. O nyere sodium salicylate onye ọrịa ya, mana onye ọrịa ahụ enweghị ike ịnara ya, ebe ọ bụ na ọ kpasoro mucosa gastric nke ukwu.

Ka afọ abụọ gasịrị, a na-akwado ọgwụ dị ka Aspirin na Berlin, ya mere acetylsalicylic acid bụ Aspirin. Nke a bụ aha dị mkpirikpi: nganiihu "a" bụ ngalaba acetyl ka ejikọtara ya na salicylic acid, mgbọrọgwụ "spir" na-egosi spiric acid (ụdị acid a dị n'ụdị ether na osisi, otu n'ime ha bụ spirea), na njedebe dị "n'ime" n'oge ahụ, a na-ejikarị aha ọgwụ.

P Asụ Ọgwụ Aspirin: ọgwụ mejupụtara

Ọ na-enyo na acetylsalicylic acid bụ Aspirin, ma molekulu ya nwere acid abụọ na-arụ ọrụ: salicylic na acetic. Ọ bụrụ na ị chekwaa ọgwụ ahụ na ụlọ okpomọkụ, mgbe ahụ, na oke iru mmiri ọ na-emebi ngwa ngwa n'ime ogige acidic abụọ.

Ọ bụ ya mere mejupụtara "Aspirin" mgbe niile nwere acetic na salicylic acid, mgbe obere oge gasịrị ihe ndị bụ isi na-adị obere. Ndụ nchekwa nke ọgwụ ahụ dabere na nke a.

Ọgwụ

Mgbe Aspirin batara n’afọ, ma banye n’ime duodenum, ihe ọ juiceụ fromụ si n’afọ anaghị eme ya eme, ebe ọ bụ na acid na-agbari ihe kachasị mma na gburugburu alkaline. Mgbe duodenum gasịrị, ọ na-abanye n'ọbara, ọ bụ naanị na enwere mgbanwe ya, a na-ahapụ salicylic acid. Ọ bụ ezie na akụrụngwa ahụ ruru imeju, ọnụọgụ nke acid na-ebelata, mana ihe ndị na-eme ka mmiri na -akpị ha na-abawanye ibu.

Ha na - agabiga arịa nke ahụ, ha ruru akụrụ, ebe enwere mpụta ya na mmamịrị. Na nsonaazụ nke Aspirin, a ka nwere obere ọgwụ - 0,5%, ma nke fọdụrụnụ bụ metabolites. Ọ bụ ha bụ ya bụ ihe mejupụtara ọgwụgwọ ahụ. Achọkwara m ịsị na ọgwụ ahụ nwere 4 ọgwụgwọ ọgwụgwọ:

  • Mgbochi ọbara egbochi.
  • Ngwongwo mgbochi mbu.
  • Mmetụta antipyretic.
  • Na-ebelata ihe mgbu.

Acetylsalicylic acid nwere akwara buru ibu, Ntụziaka nwere ndụmọdụ zuru ezu maka ojiji. Gbalia imata banyere ya nke oma ma obu ghari dọkịta.

Aspirin: ngwa

Anyị chọpụtara etu acetylsalicylic acid si arụ ọrụ. Site n’ihe ọ na-enyere anyị, anyị ga-aghota n’ihu.

  1. Tinye maka mgbu.
  2. Na oke okpomọkụ.
  3. Site na usoro mkpali dị iche iche.
  4. Na ọgwụgwọ na mgbochi nke rheumatism.
  5. Maka mgbochi nke thrombosis.
  6. Mgbochi ọnya afọ na nkụchi obi.

Ọgwụ dị mma bụ acetylsalicylic acid, ọnụahịa maka ya ga-amasịkwa onye ọ bụla, n'ihi na ọ dị ala ma na-agbanwe n'ime rubles dabere na onye nrụpụta na usoro.

Asụ Ọrịa Aspirin: ọgụ megide ọbara ọgbụgba

Ọkpụkpụ ọbara na-etolite ebe akụkụ arịa ọbara ebe ọ dị mmerụ ahụ ọ bụla na mgbidi ahụ. N'ebe ndị a, a na-ekpughere eriri ndị na-ejikọ mkpụrụ ndụ. Mpempe ọbara na-egbu oge na ha, nke na-ezochi ihe na - enyere aka ịbawanye nragide, n'ebe ndị ahụ arịa ji arịa.

Ọtụtụ mgbe, na ahụ siri ike, thromboxane na - emegide ihe ọzọ - prostacyclin, ọ naghị ekwe ka platelet rapara ọnụ ma, na - atụgharị, belata arịa ọbara. N'oge ihe ahụ mebiri emebi, nguzozi dị n'etiti ihe abụọ a na - aga n'ihu, na prostacyclin ga - akwụsị ịmịpụta. A na-emepụta Thromboxane karịrị akarị, otu platelet na-eto. Ya mere, ọbara na-aga n’arụ kwa ụbọchị nwayọ. N’ọdịnihu, nke a nwere ike ibute ọrịa obi ma ọ bụ nkụchi obi. Ọ bụrụ na a na-ewere acetylsalicylic acid mgbe niile (ọnụahịa ọgwụ ahụ, dị ka anyị kwurula, karịrị ọnụ ala), mgbe ahụ, ihe niile gbanwere n'ụzọ dị egwu.

Ihe na-eme Aspirin na - egbochi ngwa ngwa thromboxane ma na - enyere aka iwepu ya n'ahụ. Ya mere, ọgwụ a na - egbochi arịa ọbara site na mkpụkọ ọbara, mana ọ na - ewe ụbọchị 10 iji were ọgwụ ahụ, ebe ọ bụ na mgbe oge a gasịrị, platelet nwetaghachiri ikike ijikọ ọnụ.

“Aspirin” dị ka ihe mgbochi na mgbu

Ọgwụ a na - egbochikwa usoro mmebi nke ahụ, ọ na - egbochi iwepụta ọbara na saịtị nke ọnya, yana ihe ndị ahụ na - akpata ihe mgbu. O nwere ikike ịkwalite mmepụta hormone ahụ, nke na-eme ka akwara ọbara dịkwuo mma ma na-eme ka ọbara gbagoro na saịtị nke usoro mkpali ahụ. Ọ na - enyere aka wusi mgbidi nke arịa ndị dị gịrịgịrị ike. Ihe ndị a niile na --eme ka mmerụ ahụ na - egbochi ọnụnọ ma na - egbochi ya.

Dịka anyị chọpụtara, acetylsalicylic acid dị irè megide okpomọkụ. Agbanyeghị, nke a abụghị naanị uru ya. Ọ dị irè na ụdị mbufụt na mgbu niile na-eme n'ahụ mmadụ. Ọ bụ ya mere a na-ejikarị ọgwụ a na igbe ọgwụ n'ụlọ.

"Aspirin" maka ụmụaka

A na - enye Acetylsalicylic acid maka ụmụaka n'oge oke dị elu, ọrịa na - efe efe na oke mgbu. Jiri ụmụ ụmụaka na-erubeghị afọ 14 were ya nke ọma. Mana maka ndị ruru afọ 14, ị nwere ike were ọkara mbadamba (250 mg) n'ụtụtụ na mgbede.

A na-ewere "ọgwụ aspirin" naanị mgbe nri gachara, ụmụaka ga-agarrịrị mbadamba nkume ma drinkụọ nnukwu mmiri.

Mmechi

Ya mere ichikota. Kedu ihe na-enyere acetylsalicylic acid? Ọgwụ a na - enyere aka igbochi ahụ ọkụ, ọbara ọgbụgba, ọ bụ ezigbo ọgwụ mgbochi na mgbu mgbu.

N’agbanyeghi eziokwu na ọgwụ nwere ọgwụ mgbochi siri ike maka ojiji, ọ na-ekwe nkwa ọdịnihu dị mma. Ka ọ dị ugbu a, imirikiti ndị sayensị na-achọ ọgwụ ndị dị otú a nwere ike belata mmetụta mbipụta ọgwụ ahụ n'ahụ akụkụ ahụ ọ bụla. Ekwenyekwara na ọgwụ ndị ọzọ agaghị enwe ike ịchụpụ Aspirin, mana, n'ụzọ megidere, ọ ga-enwe ọhụụ.

Aspirin bụ enyi dị ize ndụ ma bụrụ onye na-eguzosi ike n'ihe

Ikekwe, ọ bụrụ na ị jụọ onye ọ bụla n’ime anyị ka anyị kpọọ ọgwụ ndị ama ama, onye ọ bụla ga-echeta otu ọgwụ. Erere a dị ịtụnanya na nwata zọpụtara anyị site na ọrịa ọkụ, na ụmụaka ndị tozurula eto na-ekele ya maka iweghachi ndụ ebilite - n'ụtụtụ, mgbe oriri na nsogbu ndị ọzọ nke ịshụbiga mmanya ọkụ. Peoplefọdụ ndị maara na maka ndị okenye, ndị dọkịta na-edekarị ọgwụ a - na obere doses, mana maka iji ya mee ihe kwa ụbọchị. Enwere ọtụtụ ọrụ maka otu penny na ọnụahịa dị ọnụ ala?

Ọgwụgwọ ọrụ ebube a nwekwara aha ọjọọ - ha na - ekwu na ọ nwere ike ibute ọnya afọ, a gaghị atụ ya aro ka ụmụaka nye ya. Onye ọ bụla na-echeta mgbasa ozi TV - banyere mbadamba ihe ndị na-eme ka ọ dị mma karịa ka ọ dị na mbụ, mana ekwenyere na ọ bụ n'aka ha ka enwere nsogbu ka njọ.

Kedu ụdị ọgwụ a bụ? N'ezie aspirin.

Ngwongwo Aspirin

Kedu otu pill na otu ogwu nwere ike isi nyere aka n'otu oge na ọrịa na-efe efe, rheumatism, migraines na ọrịa obi?

Acetylsalicylic acid nwere ihe ndị pụrụ iche. Ọ nwere ike ịkwụsị ọrụ nke enzymes cyclooxygenase (COX-1, COX-2, wdg), na-ahụ maka njikọ nke ndị mgbasa ozi mkpali - prostaglandins. N'ihi ihe nke ọgwụ aspirin, ike ọkọnọ nke usoro mmerụ ahụ na-ebelata, nke a na-eduga na nkwụghachi ya. Nke a dị ezigbo mkpa n'ọnọdụ ebe mbufụt bụ ihe na - emerụ ahụ - dịka ọmụmaatụ, yana ọrịa rheumatic.

A na - ejikọta mmetụta antipyretic na analọg nke ọgwụ aspirin na mmetụta na-akụda mmụọ na mpaghara ụbụrụ, bụ ndị na-ahụ maka thermoregulation na mmetụta mgbu. Ya mere, na oke okpomọkụ, mgbe ọnọdụ ọkụ anaghịzi enyere aka, kama ọ bụ naanị imerụ ahụ ahụ, a na-atụ aro ị drinkụ ọgwụ a.

Aspirin na - emetụta mkpụrụ ndụ ọbara - platelet, ọ na - ebelata ikike ha ijikọ aka ma guzobe mkpụkọ ọbara. Site n'iji ọgwụ eme ihe mgbe niile, ọbara ahụ “nwere ihe ọefụ ”ụ” ntakịrị, yana arịa ndị ahụ na-ebelata ntakịrị, nke na-ekpebi mmetụta enyemaka site na nrụgide intracranial dị elu na isi ọwụwa, na-enyekwa aka na mgbochi nke nkụchi obi, ọrịa strok na thromboembolism na ndị ọrịa nwere ọchịchọ nke thrombosis.

Mmetụta ọjọọ

O bu ihe nwute, uzo ihe aspirin nwekwara ihe kpatara ya. Ihe mere bụ na iwepu ọrụ cyclooxygenases (enzymes) nwere mmetụta na - adịghị mma - otu n'ime enzymes ndị a, COX-1, na-ahụ maka ịrụ ọrụ nkịtị nke mkpụrụ ndụ nke mucosa gastric. Ihe mgbochi ya na-eduga na imebi iguzosi ike n'ezi ihe nke mgbidi eriri afọ ma bụrụkwa ihe kpatara mmepe nke ọnya.

Mgbe achọpụtara ọgwụ aspirin n'akụkụ ya, ọnụọgụ nke ihe ngosi a maka ojiji ya dị ntakịrị belata: dịka iwu dị ugbu a si dị, enyeghị ya iwu maka ndị nwere ọnya afọ. Ọzọkwa, ụkwara ume ọkụ bụ ihe mgbochi na ịhọpụta acetylsalicylic acid. afọ nke ụmụaka na-erubeghị afọ 12 na ọnụnọ nke ọrịa malitere ịrịa (n'ihi ohere nke ịmalite ịmalite ọrịa Reye).

Ndị na-emepụta ọgwụ aspirin anwalela ibelata ihe na-adịghị mma na mucosa gastric site na ịmalite mmepụta nke ụdị mbadamba ọgwụ na-agbari na mmiri tupu ojiji. Agbanyeghị, sistem mmetụta nke ọgwụ ahụ mgbe a gbasịrị ya na mmetụta na-emerụ ahụ nke ihe dị mkpa nke mbadamba ndị dị otú ahụ - citric acid - na enamel ezé, abaghị uru nke ụdị ọhụrụ ahụ site na adịghị ike ya.

Mụ Aspirin

Mana enweghi ihe kpatara nsogbu ahụ - ruo taa, ndị na-ahụ maka ọgwụ ọgwụ amụla ikewapụta ihe na-egbochi ọrụ COX nke ụdị dị iche iche. Ọgwụ na-apụta na ahịa nke nwere ike, na-enweghị imerụ afọ ahụ, na - ahọrọ naanị enzyme ndị ahụ na - akpata usoro mkpali. Ọgwụ ndị a akpụpụtala obere ihe dị na ndị na - egbochi COX-2, ma na - ere ahịa ugbua n'okpuru aha ahia dị iche iche.

Ihe ndị ọzọ ọgwụ aspirin na-ewere dị ka ihe ndabere maka ọgwụ mgbochi mbufụt ọhụụ, ndị na-egbu mgbu na ndị na-ahụ maka ọgwụ mgbochi. Ma acetylsalicylic acid, ọ bụ ezie na ọ na-enye ụzọ maka "ụmụ ndị ka na-amụbawanye", ka na-anọgide na shelves nke ọgwụ ọgwụ na ọgwụ nke edepụtara na ụlọ ọrụ ahụ ike. Ọ ga - amasị m ikwu - na ụtụ, mana ihe kpatara ya bụ prosaic karịa - ọ ka bụ ụzọ kachasị ọnụ iji wedata ala, belata ihe mgbu ma gbochie mmepe nke ọrịa obi.

Iche-iche, aha na ụdị nke ịhapụ Aspirin

1. Àmà nke nchịkwa ọnụ,

2. Mbadamba ụrọ nke dị mkpa iji gbasaa ya na mmiri.

  • Mbadamba ụrọ nke dị Aspirin 1000 na Aspirin Express - 500 mg acetylsalicylic acid,
  • Mbadamba ọgwụ mkpụrụ ọgwụ Aspirin C - 400 mg nke acetylsalicylic acid na 240 mg nke vitamin C,
  • Mbadamba ụrọ Aspirin - 500 mg,
  • Mbadamba ụrọ Aspirin - 100 mg na 300 mg.

Agụnyere ihe ndị a na ụdị Aspirin dịgasị iche iche dị ka ihe inyeaka:

  • Mbadamba mkpụrụ osisi Effervescent Aspirin 1000, Aspirin Express na Aspirin C - sodium citrate, sodium carbonate, sodium bicarbonate, citric acid,
  • Mmanụ mbadamba ụrọ Aspirin - celclose microcrystalline, ahịhịa ọka,
  • Mpempe akwụkwọ Aspirin Cardio - cellulose, stachi ọka, methaclates acid na ethyl acrylate copolymer 1: 1, polysorbate, sodium lauryl sulfate, talc, triethyl citrate.

Ihe mejuputara nmekorita nke nkpuru okwu ndi ozo na ihe ndi ozo putara, n’edoro aha “Aspirin”, dika nke enyere n’elu. Agbanyeghị, ndị mmadụ na-arịa nfụkasị ma ọ bụ anabataghị ihe ọ bụla, kwesịrị ka ejiri nlezianya gụọ ihe mejupụtara ọgwụ Aspirin nke edepụtara na mpempe akwụkwọ ngwugwu ahụ na ọgwụ ahụ.

Mpempe ọgwụ aspirin na-arụ ọrụ nke ọma na maka nchịkwa ọnụ - ngosipụta maka iji

1. Iji Symptomatic mee ihe maka obi mgbu nke nsonye na ihe dịgasị iche iche:

3. Ọrịa rheumatic (rheumatism, rheumatic chorea, rheumatoid ogbu na nkwonkwo, myocarditis, myositis).

4. Collagenoses (sistemụ sistem sistem, scleroderma, system lupus erythematosus, wdg).

5. Na omume nke allergologists na immunologists iji belata larịị nke uche na guzobe na-anọgidesi ike na ndị mmadụ na-ata ahụhụ site na "aspirin ashma" ma ọ bụ "aspirin triad."

Cardio Aspirin - ihe ngosiputa maka ojiji

  • Ihe mgbochi mbu nke infarction myocardial n’etiti ndị mmadụ nwere nnukwu nsogbu nke mmepe ya (dịka ọmụmaatụ, yana ọrịa shuga, ọbara mgbali elu, cholesterol dị elu, oke ibu, ị smokingụ sịga, ndị agadi karịrị 65).
  • Mgbochi infarction myocardial,
  • Mgbapụta onya,
  • Mgbochi ọrịa ụbụrụ nke oge a,
  • Mgbochi thromboembolism mgbe a wachara ya ahụ na akwara ọbara (dịka ọmụmaatụ akwara ọbara akwara, arteriovenous shunting, angioplasty, stenting na endarterectomy nke carotid akwara),
  • Mgbochi nke thrombosis miri emi,
  • Mgbochi thromboembolism nke akwara ọbara na alaka ya,
  • Mgbochi nke thrombosis na thromboembolism nwere ogologo oge ekpughere na enweghi ike,
  • Anaghị akwụsi ike na angina,
  • Atherosclerotic ọnya nke akwara ọbara akwara (ọrịa Kawasaki),
  • Aortoarteritis (Ọrịa Takayasu).

Ọgwụ Aspirin maka Acne (nkpuchi ya na Aspirin)

  • Na-asachapụ akpụkpọ ahụ ma wepụsịa oji ojii
  • Na -ebelata abụba site na anụ ahụ,
  • Pores siri ike
  • Na-ebelata ọnya anụ ahụ,
  • Na-egbochi ịmalite nke ọnya na ọnya,
  • Kpochapu edema
  • Kpochapu ihe otutu akwara
  • Na-ewepụ sel epidermal nwụrụ anwụ
  • Na-emekwa ka anụ ahụ supple.

N'ụlọ, usoro kachasị mfe ma dị irè iji Aspirin mee ka nhazi nke anụ ahụ dị elu ma kpochapụ ihe otutu bụ ọgwụ a.Maka nkwadebe ha, ị nwere ike iji mbadamba nkịtị na-enweghị shei, zụrụ n'ụlọ ahịa ọgwụ. Ihu ihu na Aspirin bụ ụdị dị nro nke peeling kemịkal, ya mere, a na-atụ aro ka ịme ya karịa ugboro 2-3 n'izu, mgbe ụbọchị mgbe ị gbasasịrị usoro ịchọ mma, adịla na ìhè anyanwụ.

1. Maka mmanu mmanu ma di ezigbo mmanu. Ihe nkpuchi ahụ na-asachasị pores, na-eme ka anụ ahụ dị nro ma belata mbufụt. Gwuo mbadamba ọgwụ aspirin 4 n'ime ntụ ntụ ma gwakọta ya na tablespoon mmiri, gbakwunye teaspoon mmanụ a honeyụ na mmanụ ihe oriri (olive, sunflower, wdg). Tinye ngwakọta a na-esi na ya na ihu ma ịhịa ya aka na mmegharị ahụ maka minit 10, wee jiri mmiri ọkụ sachaa ya.

2. N'ihi na nkịtị nkụ. Ihe nkpuchi ahụ na-ebelata mbufụt ma na-eme ka anụ ahụ dị jụụ. Kpido mbadamba ọgwụ aspirin 3 ma gwakọta ya na tablespoon nke bred. Denye ngwakọta a gwakọtara ọnụ na ihu, hapụ maka nkeji 20 wee sachaa na mmiri ọkụ.

3. Maka akpụkpọ ahụ nwere nnukwu mbufụt. Ihe nkpuchi ahụ na-ebelata mbufụt ma gbochie ọdịdị ọnya ọhụụ. Iji kwadebe ihe nkpuchi ahụ, ọtụtụ mbadamba ọgwụ Aspirin dị ala ma wụsa ya mmiri ruo mgbe e guzobere nnukwu slurry, nke a na-etinye ya site na ntụpọ ma ọ bụ ihe otutu wee hapụ ya ruo nkeji 20, wee sachaa.

Nsonaazụ

1. Usoro nri:

  • Ihe mgbu
  • Ahụ erughị ala
  • Vomiting
  • Obi mgbawa
  • Ọbara afọ na - agba ọbara (stool ojii, ọria ọbara, ọbara anwansi na fece),
  • Ọbara anaemia
  • Ihe na-egbu afọ na ọnya ọnya afọ,
  • Mmụba ọrụ enzymes imeju (AsAT, AlAT, wdg).

2. Central ụjọ sistemụ:

  • Mmụba na-agba ọbara
  • Ọbara ọgbụgba dị iche iche (imu, gingival, uterine, wdg),
  • Heporrhagic purpura,
  • Guzobe hematomas.

4. Mmeghachi omume nfụkasị:

Analogs nke Aspirin

  • Aspivatrin mbadamba ọgwụ
  • Aspen mbadamba ihe na mbadamba ihe
  • Mbadamba aspitrin,
  • Mbadamba ọgwụ asprovit,
  • Mbadamba ụrọ Acetylsalicylic,
  • Atsbirin na-edozi mbadamba osisi,
  • Mbadamba mbadamba nkume nke Nekstrim,
  • Mbadamba nkume ndị na-enye aka
  • Upsarin Upsa mbadamba ọgwụ,
  • Mbadamba ọgwụ Fluspirin.

Ihe okwu Aspirin C bu ogwu ndia:

  • Mbo mbadamba aspivit,
  • Kwado mbadamba nkume nke C
  • Mbadamba ụrọ asprovit C
  • Upsarin Upsa nwere mbadamba mkpụrụ ndụ nke vitamin C.

Ihe okwu Aspirin Cardio bu ogwu ndi a:

Aspirin na Aspirin Cardio - onu ahia

  • Mkpokọta ọgwụ aspirin C nke mbadamba 10 - 165 - 241 rubles,
  • Aspirin Express 500 mg 12 iberibe - 178 - 221 rubles,
  • Mpempe akwụkwọ aspirin maka nchịkwa ọnụ, 500 mg 20 iberibe - 174 - 229 rubles,
  • Aspirin Cardio 100 mg 28 mbadamba 28 - 127 - 147 rubles,
  • Nkwa Aspirin Cardio 100 mg 56 mbadamba 56 - 225 - 242 rubles,
  • Aspirin Cardio 300 mg 20 mbadamba abụọ - 82 - 90 rubles.

Kedu ihe dị iche na mbadamba ASPIRIN na Acetylsallicylic Acid.

mana analgin (metamizole sodium ma ọ bụ nnu sodium) (2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl) methylamino methanesulfonic acid, ọgwụ sitere na antipyrine otu) na ihe a niile enweghị ihe ọ bụla ga-eme! nke a bụ ihe kemịkal dị iche, yana nyocha na antipyretic, mana usoro ọrụ ya kpamkpam kpamkpam! Site n'ụzọ, amachibidola ya iwu na mba niile maka ịmịpụta na ire n'ihi nsonaazụ ya

Aspirin bu ogwu eji egbochi steroidal (NSAID) A kwenyere na aha ahụ bụ “Aspirin” nwere akụkụ abụọ: “a” - sitere na acetyl na “spir” - sitere na Spiraea (dị ka a na-akpọ ahịhịa meadowsweet na Latin, bụ nke mbụ salicylic acid dịpụrụ adịpụ site na kemistal).

Kemgbe ihe karịrị otu narị afọ, ejirila ọgwụ ọgwụ aspirin mee ihe dị ka ọgwụ na ọgwụ. Ugboro ole ka anyị na-a tabletụ mbadamba ọgwụ Aspirin na okpomọkụ na mgbu. Ogwu a enweghi onu ahia ma dikwa ire ike nwere ike ihu na ezin’ulo onye obula no na ulo ogwu.

Ihe omume.Ihe mgbochi, antipyretic na analgesic. Ihe na-egosi. Rheumatism, isi ọwụwa, eze mgbu, myalgia, neuralgia, ahụ ọkụ, thrombophlebitis, mgbochi nke infarction myocardial. Ofzọ nchịkwa na usoro onunu ogwu. A na-ewere ọgwụ ọnụ site na nri. Mbadamba mbadamba ahụ wee gwerie ya ma were nnukwu mmiri mmiri downụọ ya. A na-enye ndị okenye 0.3-1 g otu ọgwụ kwa ụbọchị nke kacha nke 4 g. Inmụaka kwa ụbọchị na-adabere na afọ: ruo ọnwa 30 - 0.025-0.05 g site na afọ 2 ruo afọ 4 - 0.2-0, 8 g site na afọ 4 ruo afọ 10 - ruo 1 g site na afọ 10 ruo 15pet-0,5-1.5 g. A na-ekewa ụbọchị kwa ụbọchị n'ọtụtụ ọgwụ. Nsonaazụ. Dyspepsia, ọbara ọgbụgba, tinnitus, anụ ntị ịnụ ihe, mmeghachi ahụ nfụkasị ahụ, contraindications ACETYL SALICYLIC ACID (ASPIRINE). . Ọnya afọ na ọnya afọ, ọbara ọgbụgba, gout, ọrịa akụrụ, ịtụrụ ime. ACETYL SALICYLIC ACID (ASPIRINE)

A maara Acetylsalicylic acid n'okpuru aha akara Bayer "Aspirin".

Usoro nke ime ihe

Acetylsalicylic acid na-egbochi nguzobe nke prostaglandins na thromboxanes, ebe ọ bụ ihe na - agbanwe agbanwe na-egbochi cyclooxygenase (PTGS), enzyme nke gụnyere na njikọ ha. Acetylsalicylic acid na-arụ ọrụ dị ka onye na-ahụ maka acetylating ma na-ejikọ ìgwè acetyl na mpaghara serine dị n'etiti cyclooxygenase nọ n'ọrụ.

Emegaghị eme ihe

Otu ihe di nkpa banyere acetylsalicylic acid bu ikike ya igosiputa ihe mgbochi antiplatelet, i.e. igbochi nchịkọta na mberede nke usoro platelet.

A na - eji ọgwụ ndị nwere mmetụta antiplatelet eme ihe n'ọtụtụ ọgwụ iji gbochie egbochi mkpụkọ ọbara n'ime ndị nwere ọrịa infarction myocardial, ọrịa ụbụrụ, na ngosipụta ndị ọzọ nke atherosclerosis (dịka ọmụmaatụ, angina pectoris, transudtent interudtent), yana kwa nnukwu ọrịa obi. A na-ewere ihe ize ndụ ahụ dị ka nke "dị elu" mgbe ihe ize ndụ nke ịmalite ọrịa infroction myocardial na-adịghị egbu egbu ma ọ bụ ọnwụ n'ihi ọrịa obi na afọ 10 na-esote karịa 20%, ma ọ bụ ihe ize ndụ nke ọnwụ site na ọrịa ọ bụla obi (gụnyere ọrịa ọnya) na afọ 10 na-esote karịa 5%.

Mgbe enwere nsogbu ọbara ọgbụgba, dịka ọmụmaatụ, yana haemophilia, enwere ike ibute ọbara.

Pirinụ Ọgwụ Aspirin, ka ọ bụrụ ụzọ isi prophylaxis nke nsogbu atherosclerosis, nwere ike isi rụọ ọrụ nke ọma na ụbọchị / ụbọchị, a na-atụkwa ọgwụ a nke ọma na oke arụmọrụ / nchekwa.

Mmetụta akụkụ

Asụ ọgwụ aspirin na-enweghị nchebe kwa ụbọchị: 4 g. Do gụbiga ihe ókè na-eduga n'ọrịa akụrụ, ụbụrụ, akpa ume na umeji. Ndị ọkọ akụkọ banyere ahụike kwenyere na ojiji dị ukwuu nke ọgwụ aspirin (linear) na-arịwanye elu ọnwụ n'oge ọrịa nje 1918. Mgbe ị na-a theụ ọgwụ ahụ, ị ​​,ụ iyi nwere ike ịmalite, tinnitus na ịnụ ntị, angioedema, anụ ahụ na mmeghachi omume nfụkasị ọzọ.

Ndị a na-akpọ ulcerogenic (na-ebute ọdịdị ma ọ bụ iwe nke ọnya afọ na / ma ọ bụ ọnya duodenal) ihe a na-egosipụta na otu ogo ma ọ bụ nke ọzọ nke ọgwụ mgbochi mkpali: corticosteroid na ndị na-abụghị steroid (dịka ọmụmaatụ, butadione, indomethacin, wdg) Ngosipụta ọnya afọ na ọbara ọgbụgba na acetylsalicylic acid A kọwara ya ọ bụghị naanị site na ihe ndozi (igbochi ihe dị iche iche ọbara ọbara, wdg), kamakwa site na mmetụta mgbakasị ahụ ya na mucosa gastric, ọkachasị ma ọ bụrụ ọgwụ Jiri ụdị mkpụrụ osisi a na-adịghị agwọ ọrịa .. Nke a metụtakwara sodium salicylate. Withnyocha ogologo oge, na-enweghị nlekọta ahụike, iji acetylsalicylic acid, mmetụta ndị dị ka ọrịa dyspeptik na ọbara ọgbụgba n'ime afọ.

Iji belata utịpụta ulcerogenic na ọbara ọgbụgba, ị ga-ewere acetylsalicylic acid (na sodium salicylate) naanị mgbe ị risịrị nri, a na-atụ aro ka ị jiri nwayọ ghee mbadamba ma drinkụọ ọtụtụ mmiri mmiri (ọkacha mma mmiri ara ehi). Agbanyeghị, enwere ihe akaebe na ọbara ọgbụgba n'ime afọ nwekwara ike ibute Acetylsalicylic acid mgbe nri gasịrị. Sodium bicarbonate na - enye aka na iwepụta ihe ndị na - eme ka mmiri dị n'ime mmiri ngwa ngwa, ma, iji belata ihe ọ bụla na - ewe ya iwe, ha na - eburu mmiri alkaline ma ọ bụ ihe ngwọta nke sodium bicarbonate mgbe acetylsalicylic acid.

A na-emepụta mbadamba ụrọ acetylsalicylic acid n'ime shei (acid na-eguzogide) iji zere kọntaktị ASA na mgbidi nke afọ.

Site na iji salicylates dị ogologo oge, ekwesịrị ịcheta ohere ịba anaemia ma mee nyocha ọbara nke ọma ma nyocha ọbara ya maka ọnya.

N'ihi ohere nke nfụkasị ahụ, ekwesịrị ịkpachara anya mgbe ị na-edepụta acetylsalicylic acid (na salicylates ndị ọzọ) nye ndị nwere mmụba na penicillins na ọgwụ ndị ọzọ "allergenic".

Site na ịbawanye ụba na acetylsalicylic acid, aspirin ụkwara ume ọkụ nwere ike ịmalite, maka mgbochi na ọgwụgwọ nke ejiri usoro ọgwụgwọ agwọ ọrịa site na ịba ụba ọgwụ aspirin.

Okwesiri iburu n’uche na acetylsalicylic acid, mmetuta nke anticoagulants (okike nke coumarin, heparin, wdg), ọgwụ ndị na-ebelata shuga (usoro nke sulfonylureas) na-abawanye, ohere nke ọbara ọgbụgba na-abawanye ebe a na-eji corticosteroids na ọgwụ mgbochi mkpali ọgwụ ọnụ (NSAIDs). Nsonaazụ nke furosemide, ndị na-ahụ maka uricosuric, spironolactone nwere obere esighi ike.

N'ime ụmụaka na ụmụ nwanyị dị ime

N'ihe banyere data nnwale dị na teratogenic nke acetylsalicylic acid, a na-atụ aro ka ọ ghara ịdebe ya na nkwadebe ndị nwere ya na ụmụ nwanyị ọnwa atọ mbụ nke ịtụrụ ime.

Medicationsakingụ ọgwụ mgbu na-abụghị ọgwụ ọjọọ (aspirin, ibuprofen na paracetamol) n’oge ime na-ebute ohere nke mmerụ nwoke na nwoke n’ime ụmụ nwoke amụrụ ọhụrụ n’ụdị cryptorchidism. Nsonaazụ nke ọmụmụ a gosipụtara na n'otu oge eji abụọ n'ime ọgwụ atọ edepụtara n'oge afọ ime ka ohere nke ịmụ nwa na cryptorchidism ruru ugboro iri na isii ka e jiri ya tụnyere ndị inyom na-a notụghị ọgwụ ndị a.

Ugbu a, enwere ihe akaebe nke enwere ike ịnwe ihe acetylsalicylic acid na ụmụaka na ebumnuche nke iwetulata ọnọdụ okpomọkụ n'oge nje, oke iku ume na ọrịa febrile ndị metụtara njikọ a hụrụ na mmepe nke ọrịa Reye (Reye) (encephalopathy hepatogenic). A maghị pathogenesis nke mmepe nke ọrịa Reye's syndrome. Ọrịa malitere site na mmepe nke nnukwu ọrịa imeju. Ọnọdụ nke Reye's syndrome n'etiti ụmụaka na-erubeghị afọ 18 na United States dị ihe dị ka 1: ebe ọnụ ọgụgụ ndị nwụrụ na-erughi 36%.

Ngwongwo nri

Acetylsalicylic acid bụ obere obere agịga-dị ka kristal ma ọ bụ obere kristal ntụ ntụ, na-agbanye mmiri na mmiri ụlọ, na-agbari n'ime mmiri ọkụ, na-adị mfe ị alcoholụ mmanya, ihe ngwọta nke caustic na alkalis carbonalis.

Acetylsalicylic acid na-agbaze n'oge hydrolysis n'ime salicylic na acetic acid. A na-eme Hydrolysis site na ịkwanye ihe ngwọta nke acetylsalicylic acid na mmiri maka 30 s. Mgbe obi jụrụ, salicylic acid, nke mmiri na-agbacha nke ọma, na-ebu ụzọ kristal na-agagharị agagharị.

A na-ahụta acetylsalicylic acid na-adịghị mma na mmeghachi omume ya na Cobert reagent na ọnụnọ nke sọlfọ acid (akụkụ abụọ nke sọlfọ acid, otu akụkụ nke rebertent Cobert): ihe ngwọta ahụ na-atụgharị pink (mgbe ụfọdụ achọrọ kpo oku). Acetylsalicylic acid na-akpa àgwà na nke a kpam kpam yiri salicylic acid.

Pụ Ọgwụ Aspirin bụ ọgwụ mgbochi na - abụghị steroidal iji mee ka mgbu kwụsị, belata ahụ ọkụ, yana dịka proromlaxis nke thrombosis.

Akụrụngwa nọ n'ọrụ - acetylsalicylic acid - nwere analgesic (analgesic), antipyretic, na nnukwu doses - ọgwụ mgbochi mkpali. O nwere ihe mgbochi (na - egbochi imepụta eriri ọbara).

Usoro bụ isi nke acetylsalicylic acid bụ emesia enweghị atụgharị (mgbochi nke ọrụ) nke enzyme cyclooxygenase (enzyme nke etinyere na njikọ nke prostaglandins n'ime ahụ), n'ihi nsonaazụ nke prostaglandins na - agbagha. (Prostaglandins bụ ihe ndị dị ndụ na-arụ ọrụ n'ime ahụ. Ọrụ ha na ahụ dị ezigbo iche, ọkachasị, ha na-ahụ maka ọdịdị mgbu na ọzịza na saịtị ọnya).

Ọtụtụ mgbe, a na-eji ọgwụ aspirin mee ihe n’ị highụ ọgwụ dị elu (300 mg - 1 g) iji belata ọnọdụ okpomọkụ n’ebe ndị ọrịa nwere nnukwu akụkụ iku ume na efe efe, iji belata akwara, nkwonkwo na isi ọwụwa.

Aspirin na - enyere aka ịkwụghachi mmanya?

N'ọnọdụ ka ukwuu, ọgwụ ahụ na-enyere aka ịlụso ọrịa ọgụ ọgụ. Mbadamba mkpụrụ osisi dị mma kachasị mma ka agbazere ya na mmiri na mmanya. Ezubere ha nke ọma ibuso mgbaàmà nke mmanya na - agbakwunye ma nwee ihe mgbakwunye pụrụ iche (ihe ndị na - anabata ihe na vitamin C) nke nwere mmetụta dị n'ahụ n'ahụ.

Nke mbụ, Aspirin “na -achapụ ọbara ahụ” ma na-ebelata mgbali intracranial, nke na-eme ka onye ọrịa nwee ahụ efe n'oge adịghị anya mgbe ọ gbasasịrị.

O nwere isi ọwụwa ya na nghọta na-dokwuo anya. Na mgbakwunye, mmanya na-eme ka ọbara sie ike, nke nwere ike ibute arịa ọbara na arịa, yana acetylsalicylic acid, n'ụzọ megidere, na-agbaze ya.

Ntụziaka maka iji ọgwụ aspirin

Mbadamba nwere usoro onunu ogwu dị elu karịa 325 mg (400-500 mg na nke dị elu) ka emebere ka ọ bụrụ ihe eji eme ihe na ọgwụ mgbochi - na onunu ogwu site na 50 ruo 325 mg - tumadi dị ka ọgwụ antiplatelet.

Mmanụ mbadamba ndị a na-ewere ọnụ na mmiri dị ukwuu (iko), a na-agbanyezi mbadamba mmiri nke iko iko mmiri (ruo mgbe ọ ga-agbasa ma kwụsị ya.

Ndị okenye na ụmụaka gbara afọ 15 na-arịa ọrịa mgbu nke ịdị nwayọọ ruo na obere na ọnọdụ febrile, ntuziaka maka iji ọgwụ Aspirin na-atụ aro:

  • otu ngaji si 500 mg rue 1 g,
  • ihe kachasị otu afọ bụ 1 g,
  • kasịnụ kwa ụbọchị bụ 3 grams.

Oge etiti oge ị ofụ ọgwụ ahụ kwesịrị ịbụ opekata mpe 4.

Ogologo oge ole ka m nwere ike ị asụ ọgwụ aspirin? Theakingụ ọgwụ ahụ (na-enweghị ịgakwuru dọkịta) agaghị agafe ụbọchị 7 mgbe enyere ya ọgwụ dịka ọgwụ mgbatị ahụ na karịa ụbọchị 3 ka ọgwụ antiretretic.

Iji meziwanye ihe ọmụmụ nke ọbara - site na 150 ruo 250 mg kwa ụbọchị ruo ọtụtụ ọnwa.

Site na infarction myocardial, yana maka mgbochi nke abụọ na ndị ọrịa mgbe myocardial infarction, a na-ewere ọgwụ aspirin na ogo 40 ruo 325 mg 1 kwa ụbọchị (na-abụkarị 160 mg).

Dịka onye na - egbochi nchịkọta nchịkọta platelet - 300-325 mg kwa ụbọchị ogologo oge.

Site na nkwarụ ụbụrụ nke siri ike na ụmụ nwoke, ụbụrụ ụbụrụ thromboembolism - 325 mg kwa ụbọchị yana mmụba nke nwayọ rue ogo 1 g kwa ụbọchị. Maka igbochi nlọghachi - 125-300 mg kwa ụbọchị.

Maka mgbochi nke thrombosis ma ọ bụ nnabata nke aortic shunt, 325 mg kwa awa asaa site na eriri afọ gastran intranasal, mgbe ahụ 325 mg ọnụ ugboro 3 kwa ụbọchị (na-ejikọkarị ya na dipyridamole, nke a kagbuo mgbe otu izu gasịrị, na-aga n'ihu ọgwụgwọ ogologo oge na ASA).

Ugbu a, ị ofụ ọgwụ Aspirin dị ka ọgwụ mgbochi mkpali na ọgwụ kwa ụbọchị nke 5-8 g nwere oke, n'ihi oke ohere nke nsonaazụ akụkụ eriri afọ (NSAIDs gastropathy).

Tupu ịwa ahụ, iji belata ọbara ọgbụgba n'oge ịwa ahụ yana oge ọrụ, ịkwesịrị ịkagbu oge ahụ maka ụbọchị 5-7 wee gwa dọkịta.

Mgbe ị na-eji ọgwụ aspirin ogologo oge, a ga-eme nnwale ọbara n'ozuzu ya na nyocha ọbara ọbara.

Ọbụlagodi na obere doses, ọ na-ebelata ahụ uric acid n'ahụ ahụ, nke nwere ike ibute mmepe nke nnukwu gout na ndị ọrịa nwere oke ọrịa.

Analogs Aspirin, ọnụahịa dị na ahịa ọgwụ

Ọ bụrụ na ọ dị mkpa, ịnwere ike iji dochie anya ọgwụ Aspirin - nke a bụ ọgwụ ọjọọ:

Mgbe ị na-ahọrọ analogues, ọ dị mkpa ịghọta na ntuziaka maka iji Aspirin, ọnụahịa na nyocha nke ọgwụ nwere mmetụta ndị yiri ya anaghị emetụta. Ọ dị mkpa ịnweta ndụmọdụ nke dọkịta na ịghara ime mgbanwe ọgwụ ọ bụla.

Ọnụahịa dị na ụlọ ahịa ọgwụ Russia: mbadamba ọgwụ cellular Aspirin na-egosipụta 500mg 12pcs. - site na 230 ruo 305 rubles, mbadamba 300 mg 20 PC. - site na 75 ruo 132 rubles, dị ka ọgwụ ọgwụ 932 si kwuo.

Chekwaa n’ebe di okpomoku na okpomoku adighi n’ime 30 Celsius. Ndụ shelf bụ afọ 5. Usoro ezumike site na ụlọ ahịa ọgwụ - enweghị ndenye ọgwụ.

Mkparịta ụka ọgwụ ọjọọ

Acetylsalicylic acid na-eme ka ihe ndị mebiri emebi nke methotrexate pụta, yana mmetụta na-adịghị mma nke triiodothyronine, narcotic analgesics, sulfonamides (gụnyere co-trimoxazole), NSAID ndị ọzọ, thrombolytics - inhibitors platelet, ọgwụ hypoglycemic maka nchịkwa ọnụ. N'otu oge ahụ, ọ na-akụda nsonaazụ nke diuretics (furosemide, spironolactone), ọgwụ antihypertensive, na ọgwụ uricosuric (probenecid, benzbromarone).

Mgbe ejikọtara ya na ọgwụ ethanol, mmanya na glucocorticosteroids, mmetụta na-emebi ASA na eriri afọ na-abawanye, nke na-abawanye n'ihe ize ndụ nke ọbara ọgbụgba.

Acetylsalicylic acid na-eme ka mkpokọta lithium, barbiturates na digoxin nwee ahụ n'ahụ na-eji otu oge. Ihe antacids, nke gụnyere alumini na / ma ọ bụ magnesium hydroxide, na-ebelata ma belata ntinye nke ASA.

Aspirin dị mma ma ọ bụ jọọ njọ maka ahụ?

Abamuru nke Aspirin bụ na ọ na-enyere aka dị ka ọgwụ analgesic, antipyretic na anti-inflammatory. Na obere doses, a na-eji ya egbochi mmepe nke nsogbu vaskụla.

Taa ọ bụ sọsọ dị iche iche, ọgwụ na-esite na aka na-akwado mgbe ejiri ya na oge oke ọrịa ischemic strok (infarction ụbụrụ).

N'iji ya eme ihe mgbe nile, ihe ọghọm nke kansa colorectal, yana kansa nke prostate, nkuume, esophagus na akpịrị, belatara nke ukwuu.

Otu ihe dị mkpa uru Aspirin bara bụ na ọ na-egbochi COX, enzyme nke na - etinye aka na njikọ nke thromboxanes na Pg. Na-eme dị ka onye na-ahụ maka ihe, ASA ka nwere nsị serine dị n'etiti etiti ọrụ COX acetyl. Nke a mere ka ọdịiche dị n'etiti ọgwụ ahụ si na ndị NSAID ndị ọzọ (ọkachasị, site na ibuprofen na diclofenac), nke so n'ìgwè ndị na-egbochi ndị na-egbochi COX.

Ndị na-ahụ maka anụ ahụ na-eji agwakọta Aspirin-Caffeine-Broncholitin dị ka ndị na-ebu abụba (a na-ewere ngwakọta a dị ka progenitor nke ndị na-agba abụba niile). Ndị nwunye achọpụtala ojiji nke ASA na ndụ kwa ụbọchị: a na-ejikarị ngwaahịa ahụ iji wepu ọsụsọ na akwa ọcha ma na-agba mmiri nke ero ahụ metụrụ.

Aspirin chọpụtakwara uru maka ifuru - a na-agbakwunye mbadamba nkume na-agbaze mmiri na mmiri mgbe ha chọrọ ime ka osisi belata.

Womenfọdụ ụmụ nwanyị na-eji ọgwụ dị ka ọgwụ mgbochi: a na-ahụ ọgwụ ahụ iji intravaginally minit 10-15 tupu PA ma ọ bụ igbari ya na mmiri wee jiri nsonaazụ a na-arụpụta douche. Achọpụtaghị ịdị irè nke usoro a iji egbochi afọ ime, agbanyeghị, ndị ọkachamara n'ọrịa ụmụ nwanyị anaghị agọnarị ikike ịdị adị ya.N'otu oge ahụ, ndị dọkịta chọpụtara na arụmọrụ nke ụdị mgbochi a bụ naanị ihe dịka 10%.

Uru na ọghọm Aspirin na-adabere na ojiji ziri ezi na ịgbaso ntuziaka ahụ, n'agbanyeghị agbanyeghị akụrụngwa bara uru, ọgwụ nwere ike imerụ ahụ. Yabụ, iwepu ọrụ COX na-akpalite imebi iguzosi ike n'ezi ihe nke mgbidi nke ọwara mmiri ma bụrụkwa ihe kpatara mmepe nke ọnya afọ.

Ọzọkwa, ASA dị ize ndụ nwere ike ịbụ maka ụmụaka na-erubeghị afọ iri na abụọ. Ọ bụrụ na ejiri ọnụnọ nje nwa ya, ọgwụ a nwere ike ibute ọrịa Reye, ọrịa nke na-etinye ndụ ndị ọrịa na-eto eto n'ihe egwu.

Ahapụ Gị Ikwu