Glidiab - ntuziaka maka otu esi edochi ma ego ole ọ na-efu

Otu mbadamba ihe

ike ihe - gliclazide na usoro nke 100% ihe 80 mg,

ndị mgbe ochie: lactose monohydrate, microcrystalline cellulose, stachi nduku, hypromellose, magnesium stearate, talc, sodium carboxymethyl starch.

Mbadamba ụcha dị ọcha ma ọ bụ nke nwere agba na-acha odo odo ma ọ bụ nke nwere agba, na-adịrị cylindrical n'ụzọ, yana bevel.

Ngwongwo ogwu

Mlọ ọgwụ

Idopu ihe n’ulo di elu. Mgbe nchịkwa ọnụ nke 80 mg, oge ịta kachasị bụ awa 4, yana ntụtụ plasma kachasị bụ 2.2-8 μg / ml. Nkwukọrịta na protein plasma - 85-97%, olu nkesa - 0.35 l / n'arọ. Ekwesịrị ịtalata plasma plasma mgbe ụbọchị abụọ gachara. Oge iwepu ọkara ndụ bụ awa 8-20. Ọ na-mejupụtara ya na imeju, yana ịtọ 8 metabolites. Ọnụ ọgụgụ nke metabolite bụ isi nke a hụrụ n'ime ọbara bụ 2-3% nke ngụkọta nke ọgwụ a ,ụrụ, ọ nweghị hypoglycemic Njirimara, mana ọ nwere mmetụta na microcirculation. Ọ kpụrụ ya akụrụ - 70% n'ụdị metabolites, erughi 1% agbanweghi, site na eriri afọ - 12% n'ụdị metabolites.

Mlọ ọgwụ

Ngwunye ọgwụ hypoglycemic nke na-ahụ maka ọnya, ihe dị na usoro nke usoro nke n'ọgbọ nke abụọ. Ọ na - eme ka mmiri ọgwụ insulin na - eme ka mmiri ọgwụ insulin na - arụ ọrụ, mee ka ọ bụrụ insulin-secretory mmetụta nke glucose ma nwee mmetụta nke uru ahụ dị na insulin.

Na-akpali ọrụ nke enzymes intracellular - muscle glycogen synthetase. Na-ebelata oge dị n'etiti oge iri nri rue mmalite insulin insulin. Na-eweghachi ọkwa mbụ nke insulin (n'adịghị ka ihe ndị ọzọ sitere na sulfonylurea, dịka ọmụmaatụ, glibenclamide, nke metụtara tumadi n'oge ọkwa nke abụọ nke nzuzo). Na mgbakwunye na emetụta metabolism metabolism, ọ na-emetụta microcirculation. Ọ na - ebelata hypglycemia postprandial, na - ebelata nkwụghachi platelet na nchịkọta, na - egbu oge mmepe nke parietal thrombosis, na - egbochi vaskụla permeability ma na - egbochi mmepe nke microthrombosis na atherosclerosis, na - eweghachi usoro nke physiological parietal fibrinolysis, na ịgbaghakwa mmeghachi omume ọnya na vascular nke ọrịa nje. Na-eme ka mmepe nke ọrịa mamịrị na-arịa ọrịa retinopathy na-abụghị nke na-aba ụba, na-arịa nephropathy na-arịa ọrịa ogologo oge, a na-ahụta mbelata dị ukwuu na proteinuria. Ọ dịghị ebute mmụba n’arụ ahụ, ebe ọ nwere mmetụta kachasị na mbido insulin insulin ma ghara ibute hyperinsulinemia, ọ na - enyere aka belata oke ahụ n'ahụ ndị ọrịa buru ibu, na - agbaso nri kwesịrị ekwesị. Ọ nwere ihe anti-atherogenic, na-ebelata ịta nke cholesterol n'ime ọbara.

Usoro onunu ogwu na nhazi

N'ime, n'oge nri, ọgwụ a tụrụ aro mbụ bụ 40 mg (½ mbadamba), mkpụrụ mbụ a na-eme kwa ụbọchị bụ mg mg (1 mbadamba), nkezi ụbọchị kwa ụbọchị bụ 160 mg (mbadamba abụọ n'ime 2 ntụtụ, n'ụtụtụ na mgbede). mg (4 mbadamba n’ime ụzọ abụọ kewara - ụtụtụ na mgbede). Ọgwụ ya na-adabere na afọ, ogo nke ọrịa shuga, ịba ụba nke glucose n'ọbara na afọ efu na awa 2 mgbe ị risịrị nri.

Enwere ike ịgbanwe mgbanwe ọ bụla na - esote izu ma ọ dịkarịa ala izu abụọ. Ọ bụrụ na ọgwụ ahụ funahụrụ ya, yabụ echi ya ekwesịghị ịba ụba ọgwụ a.

N'ime ndị ọrịa merela agadi ma ọ bụ na ezughi oke akwara na-adịghị ala ala na mmerụ ahụ dị mkpụmkpụ (mwepụ nke creatinine - 15-80 ml / min), a na-enye ọgwụ ahụ n'otu usoro.

Ihe ngbanwe

hypersensitivity na gliclazide ma ọ bụ akụrụngwa inyeaka nke ọgwụ ahụ, yana ọgwụ ndị ọzọ na-enye sulfonylurea.

ụdị shuga 1

precca na-arịa ọrịa mamịrị

nnukwu ịba ọcha n'anya na / ma ọ bụ akụrụ oke

concomitant ọgwụ na miconazole

ime, lactation

ụmụaka na ndị ntorobịa erubeghị afọ iri na asatọ

Jiri nlezianya

Okenye, enweghi usoro na / ma obu ihe oriri na-edozi ahụ, ọrịa siri ike nke akwara obi (gụnyere ọrịa obi na akwara, atherosclerosis), hypothyroidism, adrenal or pituitary insufficiency, hypopituitarism, renal na / ma ọ bụ imeju, ogologo glucocorticosteroid therapy, mmanya , ụkọ glucose-6-phosphate dehydrogenase, ọgwụgwọ concomitant na phenylbutazone na danazole.

Nsonaazụ

- hypoglycemia (nke megidere usoro usoro onunu ogwu na nri ezughi oke)

- isi ọwụwa, ọgbụgbọ, ike ọgwụgwụ, agụụ, ọsụsọ, ike adịghị ike

- palpitations, arrhythmia, mmụba ọbara

- ura, ura, nkpasu iwe, nkpasu iwe, nchekasị, ogba aghara, mkpochapu ahihia, enweghi ike itinye uche na mmegharia nwayo, obi uto, anya isi.

- aphasia, shoor, paresis, nsogbu uche, mmetụta nke enweghị enyemaka,

njide onwe onye, ​​iche echiche, ihe ima aghara

- enweghị ume, bradycardia, ọnwụ nke mmụọ

- ọgbụgbọ, ọgbụgbọ, mgbu afọ, afọ ntachi, afọ ọsịsa (ogo na-ebelata nri)

- arụrụ ọrụ imeju (ịba ọcha n'anya, cholestatic jaundice - chọrọ ịkwụsị ọgwụ, mmụba ọrụ nke “imeju” transaminases, alkaline phosphatase)

- mgbochi nke ụmị ọkpụkpụ (anaemia, thrombocytopenia, leukopenia, granulocytopenia)

- mmeghachi omume nfụkasị: nchacha akpụkpọ, urticaria, ọnya akpụkpọ (gụnyere maculopapular na bullov), erythema

- nsonaazụ ndị na - esokarị na usoro sulfonylurea: erythropenia, agranulocytosis, hemolytic anaemia, pancytopenia, vasculitis nfụkasị, ọrịa imeju na - egbu ndụ.

Mkparịta ụka ọgwụ ọjọọ

Na-akwalite nsonaazụ anticoagulants (warfarin); enwere ike ịchọrọ ịhazigharị ọgwụ anticoagulant.

Miconazole (ya na usoro nchịkwa na mgbe ị na-eji gel na mucosa oral) na-eme ka mmetụta hypoglycemic nke ọgwụ ahụ dị elu (hypoglycemia nwere ike ịmalite ruo na coma).

Phenylbutazone (usoro nchịkwa) na-eme ka mmetụta hypoglycemic nke ọgwụ ahụ pụta (na-apụ n'ihi protein nke plasma na / ma ọ bụ na-akwụsịlata ahụ), njikwa glucose ọbara na mmezi nke glyclazide dị mkpa, ma n'oge nchịkwa phenylbutazone na mgbe ọpụpụ ya.

Ọgwụ ethanol na ọgwụ ethanol nwere hypoglycemia, na-egbochi mmeghachi ụgwọ nkwụghachi ụgwọ, nwere ike inye aka na mmepe nke hypoglycemic coma.

Site na nchịkwa nke oge a na ọgwụ ndị ọzọ hypoglycemic (insulin, acarbose, biguanides), beta-blockers, fluconazole, angiotensin na-agbanwe enzyme inhibitors (ACE) (captopril, enalapril), H2-histamine recepor blockers (cytoxidamides, cytaminidamines) na ọgwụ mgbochi mkparị - steroidal - ịba ụba hypoglycemic na ihe egwu nke hypoglycemia.

Danazole na-akpata ọrịa mamịrị. Mgbe ejikọtara ya na gliclazide, ọ dị mkpa ijikwa glucose ọbara ma mezie ọnụọgụ nke gliclazide, ma n'oge nchịkwa danazol na mgbe ọpụpụ ya.

Chlorpromazine na ọnụọgụ dị elu (karịa 100 mg / ụbọchị) na-abawanye ọdịnaya glucose na ọbara, na-ebelata ihe nzuzo nke insulin. Ọ dị mkpa ijikwa glucose ọbara ma dozie dose nke gliclazide, n'oge nlekọta nke chlorpromazine na mgbe ọpụpụ ya.

Glucocorticosteroids (usoro, intraarticular, mpụga, nchịkwa rectal) na-abawanye glucose ọbara na mmepe nke ketoacidosis nwere ike (ibelata ndidi na-anabata carbohydrate). Ọ dị mkpa ijikwa glucose ọbara ma dozie dose nke gliclazide, ma n'oge nchịkwa nke glucocorticosteroids na mgbe mwepu ha gasịrị.

Ritodrin, salbutamol, terbutaline (iv) - mụbaa glucose ọbara. A na-atụ aro nchịkwa glucose ọbara ma, ọ bụrụ na ọ dị mkpa, nyefee onye ọrịa na ọgwụgwọ insulin.

Ntụziaka pụrụ iche

Mgbe ị na-a theụ ọgwụ ahụ, mkpebi siri ike nke ibu ọnụ glucose ọbara na-arịa ọbara na hemoglobin glycosylated dị mkpa.

Nnukwu ịwa ahụ na mmerụ ahụ, oke ọkụ, ọrịa na-efe efe na ọrịa febrile nwere ike ịchọ ịkwụsị ọgwụ hypoglycemic nke ọnụ na nchịkwa nke insulin.

E kwesiri ịdọ ndị ọrịa aka na ntị gbasara ịba ụba nke hypoglycemia n'ihe banyere ị etụ ọgwụ ethanol na ọgwụ ethanol nwere (gụnyere mmepe nke disulfiram dịka mmeghachi omume: mgbu afọ, ọgbụgbọ, ọgbụgbọ, isi ọwụwa), ọgwụ mgbochi na-abụghị steroidal, na agụụ.

Imeghari otu ọ̀ dị mkpa maka ịghara oke nri anụ ahụ na nke mmetụta uche, mgbanwe nri.

Dịka iwu, akara nke hypoglycemia na-apụ n'anya mgbe ị risịrị nri bara ụba na carbohydrates (dịka ọmụmaatụ, shuga), ịenụ ihe na-atọ ụtọ anaghị enyere aka iwepụ ọrịa hypoglycemic. Hypoglycemia nwere ike ịmaliteghachi n'agbanyeghị enyemaka mbụ dị irè. Ọ bụrụ na ọrịa hypoglycemic siri ike ma ọ bụ daba ogologo oge, ọbụlagodi n'ọnọdụ ndozi nwa oge mgbe ị risịrị nri nwere carbohydrates, nlekọta ahụike mberede dị mkpa, ruo ụlọ ọgwụ.

Karịsịa mmetụta nke ọgwụ hypoglycemic bụ ndị agadi, ndị ọrịa na-anaghị enweta nri edozi, yana ọnọdụ adịghị ike, ndị ọrịa na-ata ahụhụ site na enweghi nri. A ga-ekpuchi ngosipụta nke ọrịa hypoglycemia mgbe ị na-ewere beta-blockers, clonidine, reserpine, guanethidine. Mmepe nke iguzogide ọgwụ nke abụọ ga - ekwe omume (a ghaghị ịpụ iche na nke mbụ, nke ọgwụ a anaghị enye nsonaazụ a na-atụ anya na nnọkọ mbụ).

Cribdebere ọgwụ ọrịa sulfonylurea nye ndị ọrịa nwere ụkọ glucose-6-phosphate dehydrogenase (G6PD) nwere ike ibute anaemia haemolytic. Ekwesịrị ịkpachara anya mgbe ị na-ede akwụkwọ banyere Glidiab na ndị ọrịa nwere ụkọ G6PD ma na-atụle ohere nke ọgwụgwọ ọzọ na klas ọzọ nke ọgwụ.

Nhazi nke ọgwụ ahụ gụnyere lactose monohydrate, n'ihe metụtara nke a, ekwesighi iji Glidiab mee ihe na ndị ọrịa nwere ọrịa galactosemia, glucose-galactose malabsorption, na ụkọ lactase.

Akụkụ nke nsonaazụ ọgwụ ahụ nwere ike ịnya ụgbọ ma ọ bụ usoro nwere ike ibute

N'oge ọgwụgwọ, a ga-akpachara anya mgbe ị na-anya ụgbọ ala ma na-eme ihe ndị ọzọ nwere ike ịdị ize ndụ chọrọ mmụba nlebara anya na ọsọ nke mmeghachi omume psychomotor.

Dodoụbiga ya ókè

Ọrịa: hypoglycemia, nsogbu adịghị, hypoglycemic coma.

Ọgwụgwọ: ọ bụrụ na onye ọrịa maara, ịmịnye shuga, n'ihe banyere nsụ isi ọfụma, iv nhazi nke 40% dextrose, mgbe ahụ iv 5% dextrose na-adalata ruo mgbe mgbanye ọbara ọbara ruru 5.55 mol / l, 1-2 mg glucagon v / m, na-ahụ maka ịba ụba nke glucose n'ime ọbara kwa nkeji iri na ise, yana ịchọpụta pH, urea, creatinine na electrolytes n'ime ọbara. Mgbe ọ nwetasịrị, ọ dị mkpa inye onye ọrịa ahụ nri nwere nnukwu carbohydrates na-adị ngwa ngwa (iji zere ịmalite ịmalite hypoglycemia). Na ọrịa ụbụrụ, mannitol na dexamethasone. Dialysis adighi ike.

Emeputa

AKRIKHIN OJSC, Russia,

142450, mpaghara Moscow, Noginsky district, obodo Staraya Kupavna,

Ekwentị / Faksị: (495) 702-95-03.

Aha na obodo nke akwụkwọ ikike ndebanye aha

AKRIKHIN OJSC, Russia,

Adreesị nke nzukọ a na-anabata mkpesa nke ndị na-azụ ahịa banyere ịdị mma nke ngwaahịa (ngwongwo) n'ókèala nke Kazakhstan:

AKRIKHIN OJSC, Russia,

142450, mpaghara Moscow, Noginsky district, obodo Staraya Kupavna,

Kedu ka Glidiab MV

Achọrọ njikwa glycemic siri ike iji gbochie ọrịa shuga na-egbu oge. Dịka iwu, usoro ọgwụgwọ gunyere mmezi nke nri na-arụ ọrụ na ọrụ. Site na oria nke 2, usoro ndị a anaghị ezuru, yabụ ajụjụ na-ebilite nhọpụta nke ọgwụ ịdalata shuga. Ejiri ọkwa mbụ nke ọrịa ahụ bụ nnabata insulin na mmụba nke glucose na imeju, yabụ n'oge a ọgwụ kachasị dị mma bụ metformin (dịka ọmụmaatụ, Glucofage).

Ọrịa hyperglycemia na obere oge na obere oge na-eduga na dysfunction pancreatic cell yana njikọ insulin. Mgbe mgbanwe ndị dị otú a bidoro, ọ ga-adị mma ka ịgbakwunye mbadamba ụrọ na usoro ọgwụgwọ enyere na mbụ nwere ike ịkwalite mmepụta insulin. N'ime ọgwụ ndị dị ugbu a, ndị na-egbochi DPP4, ihe ndị na-emetụta mpụ, na sulfonylureas nwere ike nke a.

A na-eji otu abụọ mbụ eme ihe n'oge na-adịbeghị anya, ọ bụ ezie na ọgwụ dị irè, ma ọ dị oke ọnụ. N'ọtụtụ mpaghara Russia, inweta ha n'efu bụ nsogbu. Mana usoro dị ọnụ ala nke sulfonylureas na-ekwe nkwa ka enye ya ọgwụ n’ụlọ ọgwụ ọ bụla. Ihe kachasị dị nchebe na ọgwụ ọhụụ ugbu a bụ glimepiride (Amaryl) na ụdị glyclazide (Diabeton MV na analogues, gụnyere Glidiab MV)

Ọrịa mamịrị bụ ọgwụ izizi, Glidiab bụ ụlọ dị n'ọdịdị dị mma. Nnyocha e mere gosiputara ihe otu ọgwụ ndị a si emetụta glycemia.

Ntuziaka maka iji kọwaa ọtụtụ ihe bara uru nke Glidiab:

1. Iweghachite usoro nke insulin nke mbu, n'ihi shuga malitere ịhapụ arịa ndị ahụ ozugbo nnata.
2. Amplification 2 akụkụ.
3. Mbelata adhesion platelet, mee ka ikike nke epithelium vaskụla na-eme ka ọ gbasaa thrombi. Mmetụta a na - ebelata ohere ọrịa vaskụla na-akpata.
4. Neutralization nke free radicals, nke ọnụ ọgụgụ ya na-abawanye na ọrịa shuga.

Enwere nnyocha na-egosi na nhazi nke sulfonylurea na-eweta mbibi nke mkpụrụ ndụ beta, na-eduga na enweghi ike insulin ma na-amanye ndị ọrịa mamịrị ịgbanwe insulin. Glidiab n'ime ndị otu ya bụ otu n'ime ọgwụ kachasị nchebe na nke a. Nkezi ọgwụ a na-eme ka njikọ hormone na-eto 30%, emesia ihe mmepụtara ya na-agbadata 5% kwa afọ. Na usoro eke ọrịa a, ụkọ insulin na-abawanye kwa afọ site 4%. Nke ahụ bụ, ọ gaghị ekwe omume ịkpọ Glidiab kpamkpam maka ọrịa, ma ọ gaghị ekwe omume ịgụnye ya na ọgwụ ndị siri ike site na otu ahụ, dịka ọmụmaatụ, Maninil.

Ihe ngosi maka nhọpụta nke ọgwụ

Dịka ntuziaka ahụ si dị, a na-enye Glidiab naanị ndị ọrịa mamịrị nwere ụdị ọrịa 2 nke nsogbu carbohydrate. Mmetụta ọgwụ ahụ na-eduzi ozugbo na mkpụrụ ndụ beta, bụ ndị na-anọghị na ụdị ọrịa shuga 1. Ekwesiri ijikọ usoro ọgwụgwọ yana nri na mmega ahụ, yana oke ibu na / ma ọ bụ insulin na-eguzogide, a na-agbakwunye metformin.

Edere Glidiab naanị dị ka njikọta metformin, naanị mgbe onye ọrịa mezuru usoro ọgwụ niile, mana enweghị ike iru mgbatị ahụ. Dịka iwu, nke a na-egosi mfu nke arụ ọrụ akwara. Iji hụ na erughi insulin na mkpa Glidiab, ọ dị mma ị were ule C-peptide.

Na nmalite ọrịa ahụ, a na-enye ọgwụ ahụ naanị ma ọ bụrụ na shuga dị n'ọbara dị elu, na enwere obi abụọ na a chọpụtara ọrịa shuga ọtụtụ afọ mgbe ọ gasịrị ka ọ malitere.

Usoro onunu ogwu na usoro onunu ogwu

Emeputa rụpụtara Glidiab n'ụdị abụọ:

1. Glidiab onunu ogwu nke 80 mg. Ndị a bụ mbadamba ọdịnala nke nwere gliclazide, ihe dị ike si na ha na-abanye n'ime ọbara ngwa ngwa wee banye n'ọtụtụ kachasị elu mgbe awa anọ gachara. Ọ bụ n'oge a ka ihe egwu kachasị nke hypoglycemia. A na-ekewa dose karịrị 160 mg n'ime usoro abụọ, ya mere, shuga nwere ike ịda ugboro ugboro n'ụbọchị.
2. Glidiab MV bụ ihe ọhụụ ugbu a, a na-eme mbadamba ụzọ n’ụzọ gliclazide si ha na-abanye n’ọbara nwayọ nwayọ. Nke a bụ ihe akpọrọ gbanwee, ma ọ bụ ogologo oge, ntọhapụ. Site na ya, mmetụta nke Glidiab na-abawanye nke ọma ma a na-echekwa ogologo oge n'otu ọkwa ahụ, nke na-abawanye arụmọrụ nke ọgwụ, na-ebelata ọgwụ dị mkpa, ma na-ezere hypoglycemia.

Ọdịiche dị na ọnụahịa dị n'etiti ọgwụ ndị a pere mpe - Glidiab MV dị ọnụ karịa ihe ruru ru ru 20, na ọdịiche n'ihe nchekwa dị oke mkpa, yabụ, onye nrụpụta na-atụ aro ka ndị nwere ọrịa shuga gbanwee na ọgwụ ọhụrụ. Dabere na arụmọrụ ya, 1 mbadamba nkume nke Glidiab 80 bụ 1 mbadamba nke Glidiab MV 30.

Usoro ọgwụgwọ a tụrụ aro:

Iwu nke ịbawanye usoro onodu ogwu dika ntuziaka maka ojiji: ọ bụrụ na ịmalite ịmalite ezughi oke, enwere ike ịbawanye 30 mg (80 maka Glidiab) mgbe ọnwa nke nchịkwa gasịrị. Nwere ike iwelie ọgwụ a naanị tupu ndị ọrịa shuga ndị shuga ọbara agbanwebeghị. Mmụba ngwa ngwa na usoro onunu ogwu dị ize ndụ na hypoglycemic coma.

Otu esi eji Glidiab

Glidiab

Glidiab MV

Dị ka ndị dọkịta si kwuo, ndị ọrịa nwere ọrịa na-adịghị ala ala anaghị a medicinesụ ọgwụ niile enyere ha aka. Site n'ọrịa shuga 2dị nke abụọ, nsogbu adịghị n'ọbara glucose ọbara dị elu, ya mere, a na-amanye ndị ọrịa ị statụ ọgwụ, aspirin, na ọgwụ ọbara mgbakwunye na ọgwụ ndị na-ebelata shuga. Ebe a na-enyekwu mbadamba mbadamba ụgwụ, ọ bụrụkwa na usoro usoro onyunyo ana-agbakasị ahụ, ọ ga-eme ka ike ha beụbiga mmanya ókè. A na-ewere Glidiab MV otu ugboro n'ụbọchị, n'agbanyeghị usoro ị presụ ọgwụ enyere gị, yabụ, o yikarịghị ka ị ga-atụfu ọgwụ ahụ.

Dọkịta nke Sciences Medical, Isi nke Institute of Diabetology - Tatyana Yakovleva

M na-amụ ọrịa shuga kemgbe ọtụtụ afọ. Ọ na-atụ ụjọ mgbe ọtụtụ mmadụ nwụrụ, nweekwa nkwarụ karịa n'ihi ọrịa shuga.

Emere m ngwa ngwa izisa ozi ọma - Endocrinological Research Center nke Russian Academy of Medical Sciences jisiri ike mepụta ọgwụ na-agwọ ọrịa shuga kpamkpam. N'oge a, ịdị irè nke ọgwụ a na-eru nso 98%.

Ozi ọma ọzọ: Ministri Ahụike echekwaala maka mmemme pụrụ iche nke na-akwụ ụgwọ ọgwụ dị elu. Na Russia, ndị ọrịa mamịrị ruo Mee Mee 18 (isonye) nwere ike inweta ya - Naanị 147 rubles!

Gịnị bụ mmetụta ndị ọ na-enwe?

Ndepụta nke mmetụta na-adịghị mma nke ga-ekwe omume mgbe ị na-ewere Glidiab MV 30 mg na analogues:

1. Hypoglycemia na-ewere ọnọdụ nke ị drugụ ọgwụ gabigara ókè, na-ahapụ nri ma ọ bụ enweghị carbohydrates na ya. Mkpụrụ mmiri shuga na-eme ugboro ugboro chọrọ mgbazi nke nri na mbelata dose Glidiab.
2. Ọgba aghara digestive. Iji belata ihe egwu dị na nsonaazụ a, ntuziaka a na-atụ aro iwere Glidiab n'otu oge ahụ nri.
3. Ahụ akpụkpọ ahụ. Dabere na nyocha, mmeghachi omume nfụkasị ahụ dị oke njọ anaghị ewere ọnọdụ.
4. Gbanwee ọdịnaya nke mmiri mejupụtara. Otutu mgbe enwere ike idoghari ya, ya bu, onwe ya napu onwe ya mgbe akwusiri nnabata.

A na - ekwu na ihe ga - eme ka hypoglycemia dị ihe dị ka 5%, nke dị ntakịrị karịa ka ọ dị na nke sulfonylureas okenye. Ndị mmadụ na-arịa ọrịa shuga mellitus yana ọrịa siri ike nke obi na endocrine, yana ị na-ewere homonụ ogologo oge, na-adịkarị mfe ịdalata shuga. Maka ha, ọgwụ Glidiab kachasị nyere ohere bụ nke 30 mg. Ndị ọrịa mamịrị na-arịa neuropathy, ndị agadi, ndị ọrịa nwere obere hypoglycemia na-adịkarị ma ọ bụ na-adị ogologo oge, na-akwụsị inwe ihe mgbaàmà nke shuga dị ala, yabụ ị Gụ Glidiab nwere ike ịdị ize ndụ nye ha. N'okwu a, a na-atụ aro mbadamba shuga ndị na-enweghị ụdị mmerụ ahụ.

Ihe analogues ama ama

N'ime mbadamba ọgwụ antidiedi maka ịgwọ ụdị ọrịa 2, ọ bụ nhazi glyclazide bụ nke ekesara ka ekesa. Naanị Metformin nwere ike ịsọ mpi ha ọnụ ọgụgụ aha aha ụghalaahịa. A na-eme ọtụtụ analogues Glidiab na Russia, ọnụahịa ha na ụlọ ahịa ọgwụ dịgasị iche n'etiti 120-150 rubles, ọnụ ala French Diabeton kachasị dị ọnụ ahịa bụ ihe dịka 350 rubles.

Glidiab analogs na nnọchi:

Glidiab ma ọ bụ Gliclazide - nke ka mma?

A na-ekpebi ogo ọgwụ ka ogo nke ịdị ọcha na nzipụta nke usoro ihe eji arụ ọrụ, nchekwa nke ihe inyeaka. Glidiab na Glyclazide (mmepụta nke Ozone) bụ nnọọ otu ihe n'ụzọ ndị a. Akrikhin na Ozone nwere akụrụngwa ọhụụ, ụlọ ọrụ abụọ ahụ anaghị emepụta ọgwụ ọgwụ n'onwe ha, mana zụta ya, ọzọ, site na otu ndị China na-emepụta. Ma na nchikota nke ndị ochie, Glidiab na Gliclazide fọrọ nke nta ka ha na-ekwugharị. Nyocha nke ndị na-a takingụ ọgwụ ndị a kemgbe ihe karịrị otu afọ na-egosi na ha nhatanha na ọrịa shuga.

Glyclazide nwere nhọrọ ọnụọgụ abụọ - 30/60 mg, Glidiab - naanị 30 mg, enwere ike gbanwee Glidiab na ntọhapụ mbụ, a na-emepụta Gliclazide naanị ịgbatị - nke ahụ bụ ọdịiche niile dị n'etiti mbadamba nkume ndị a.

Usoro nke iji mee ihe na ihe ngosipụta maka ojiji

Glidiab MV bụ onye nnọchianya hypoglycemic nke dị na otu nke usoro sulfonylurea nke ọgbọ nke abụọ. Ọgwụ a mejupụtara gliclazide na excipients. Glyclazide n'ime otu mbadamba nwere 80 mg ma ọ bụ 30 mg.

Kedụ ka akụrụngwa dị ike nke ọgwụ ahụ si arụ ọrụ? Glyclazide n'elu mmiri na-akpali akwara glycogen synthetase na ọrụ insulin. Ọzọkwa, ihe a na -eme ka mmetụta insulin nke glucose na-arụ ọrụ, ma na-enye aka na mmụba nke akwara ndị dị na insulin.

Ọzọkwa, gliclazide na-enyere aka belata oghere dị n'etiti oriri nri yana mmalite nke insulin na-arụ ọrụ. Ọ bụrụ na inyocha ntuziaka maka iji Glidiab, ị nwere ike ịchọpụta na mgbe ị na-eji mbadamba mbadamba, oke hyperglycemia na-ebelata, na ịmaliteghachi mkpụrụ ndụ insulin n'oge.

Ihe ndị a niile metụtara metabolism metabolism na microcirculation. Ọ bụrụ na ị kwenyere na ntuziaka ahụ, Glidiab MV na - enyere aka belata nrachi na nchịkọta nke platelet, n'otu oge ahụ ibido vaskụla permeability. N'ikwu ya n'ụzọ dị mfe, n'iji mbadamba nkume, ohere nke microthrombosis na atherosclerosis na-ebelata nke ukwuu.

Nnyocha achọpụtawo na onye na-ahụ maka hypoglycemic na-enyere aka belata mmepe nke nsogbu dị ka ọrịa mamịrị retinopathy na-arịa ọrịa na-abụghị protinerative. Ọzọkwa, iji mbadamba nkume Glidiab MV nwere ike ịbawanye uru nke usoro ọgwụgwọ nri na ndị ọrịa buru ibu.

Ọ ga-amasị m ịchọpụta na a na-ekekọta metabolites nke ọgwụ ahụ na mmamịrị n'ụdị na-agbanweghị agbanwe, yana yana anụ ahụ n'ụdị metabolites.

Ntuziaka maka iji ọgwụ ahụ

N'ọnọdụ ndị dị a isaa ka ọ dị mma iji mbadamba 80 Glidiab? Ntụziaka ahụ na-ekwu na ọ bụ ihe amamihe dị na ya iji ọgwụ a na-agwọ ụdị ọrịa shuga mellitus 2, ọ bụrụ na ọgwụgwọ nri na mmega ahụ anaghị enyere aka mee ka ọkwa glucose dị mma.

Na njikọta ọgwụ ndị ọzọ, Glidiab MB adịkarịghị eji ya. Mana ekwesịrị iburu n'uche na enwere ike ịbawanye hypoglycemic nke ọgwụ ahụ ma ọ bụrụ na, ya na ọgwụ ọgwụ, iri nri na egwuregwu.

Etu esi ewere ogwu? Ọgwụ nke mbụ bụ 80 mg. Ọzọkwa, ugboro ole a na-eji ya ugboro abụọ n'ụbọchị - n'ụtụtụ na n'anyasị. A na-atụ aro ka ị were mbadamba mbido 30-60 tupu iri nri.

Ọ bụrụ na obere opekata mpe nke 80 mg enweghị mmetụta hypoglycemic, mgbe ahụ usoro a ga-eji nwayọ mụbaa. N’emekarị, n’ụdị shuga nke abụọ, ọ̀tụ̀tụ̀ ọgwụ ọgwụ mgbochi 160 dị mma. Oke ike ị were nkwụ ọgwụ a bụ 320 mg.

Mana anyị aghaghi icheta na site na ịba ụba nke onunu ogwu, ohere nke hypoglycemia na nsogbu ndị ọzọ na-abawanye nke ukwuu.

Njikọ Ọgwụ na Contraindications

Ekwesịrị icheta na ọtụtụ ọgwụ ike ịbawanye ike hypoglycemic nke ọgwụ Glidiab MB. Yabụ, ntuziaka ahụ kwuru na ekwesịrị ịgwakọta ọgwụ ahụ nke ọma na mgbochi mgbochi histamine H2, ọgwụ mgbochi mkpali, ọgwụ mgbochi, AC inhibitors.

Ọgwụ mgbochi ụkwara nta, beta-adrenoblockers, anticoagulants anumanu coularin na-apụtakarị, anabolic steroid, MAO inhibitors, salicylates na ndị ọzọ na-enwe ike ịbawanye mmetụta hypoglycemic.

Ọ bụ ya mere, tupu iji mbadamba Glidiab, ị kwesịrị iji nlezianya mụọ ntuziaka ahụ ma kpọtụrụ dọkịta.

Otu n'ime ihe contraindications maka iji mbadamba osisi nwere ike mata:

1. Ọrịa shuga 1dị nke 1 bụ insulin-based
2. Ọrịa mamịrị ketoacidosis.
3. Precomatous ma ọ bụ coma. Ọzọkwa, contraindication siri ike bụ hyperosmolar coma.
4. Leukopenia
5. Oge ime.
6. Oge ịgba akwụkwọ.
7. Ọrịa ịba ọcha n'anya na akụrụ.
8. Ọnọdụ ndị a na-esonyere na imebi usoro oriri, yana mmepe nke hypoglycemia. Ọnọdụ ndị dị otú ahụ gụnyere mgbochi afọ, paresis nke afọ na ọrịa na-efe efe.
9. Ihe ndị na-enye nsogbu na mbadamba ihe.
10. Ọnọdụ enwere ike ịchọ ọgwụ insulin. Ọnọdụ ndị a gụnyere apa ọkụ, mmerụ ahụ, ma ọ bụ ịwa ahụ.
11. Mmanya
12. Ọrịa Febresi.

Ọzọkwa, a ga-eji ọgwụ ahụ kpachara anya na ndị mmadụ na-arịa dysfunction thyroid.

Nyocha na nsonaazụ nke Glidiab

Kedu ihe nyocha banyere Glidiab? Ndị ọrịa mamịrị na-anabata ọgwụ ọma. Ọtụtụ ndị mmadụ na-adọta ọnụ maka ọgwụ ọnụ ala dị ala, yana nrụpụta dị elu.

Ọzọkwa, Gladiab dịka ndị na-arịa ọrịa shuga dị mma maka na ọ naghị akpata oke mmetụta na obere usoro. Njirimara ozo nke ogwu a nyere ndi mmadu bu eziokwu na o na-abawanye odi nma na usoro ọgwụgwọ nri.

Mmetụta ndị dị a canaa ka ọgwụ hypoglycemic nwere ike ịkpata? Dịka ntuziaka ahụ si dị, ọgwụ nwere ike ibute:

• Mmebi nke usoro endocrine. Ha gosipụtara dị ka hypoglycemia. Mana ekwesịrị iburu n'uche na nsogbu a na - apụta na ọ bụ naanị n'usoro ọgwụ a akwadoghị.
• Iwe iwe, iro ụra, mwakpo nke oke iwe, ụjọ nke aka na ụkwụ, isi ọwụwa, ike ọgwụgwụ, ike ọgwụgwụ.
• Nda anya visual acuity.
• Aphasia.
• Bradycardia
• Igwe iku ume.
• Delirium.
• Thrombocytopenia, anaemia, leukopenia.
• Mmeghachi omume nfụkasị ahụ.
• Sistem nri nri. Mmadu nwere ike inwe oria afọ, obi uto na mpaghara epigastric, ọgbụgbọ, anorexia, cholestatic jaundice, ịba ụba nke ọrụ ịba ọcha n'anya.

Ọtụtụ mgbe, mmetụta ndị na-edozi onwe ha na-edozi onwe ha mgbe ha kwụsịrị ọgwụ ahụ ma na-anata ọgwụgwọ Symptomatic kwesịrị ekwesị.

Analogue kacha mma nke Glidiab

Kedu ihe bụ analogues nke Glidiab? Kama nke ahụ, enwere ike iji hypoglycemic dị iche iche na-adabere na metformin hydrochloride. Otu analog dị irè bụ Usoro. Ọgwụ a bụ onye Glidiab kacha anọchi anya ya.

Ọnụ ego ọgwụ a dị ihe dị ka 180-260 rubles. Inedị dị n'ụdị 500 mg, 850 mg na 1 gram. Otu ngwugwu nwere mbadamba 60. Ihe mejupụtara ọgwụ ahụ gụnyere metformin hydrochloride, povidone, primellose, magnesium stearate.

Kedụ ka akụkụ ọrụ mmanye dị n'ọrụ si arụ ọrụ? Ntụziaka ahụ na-egosi na metformin hydrochloride gbochiri usoro gluconeogenesis na imeju, ma na-enyere aka belata nnabata glucose site na eriri afọ.

Ọzọkwa, akụrụngwa nọ n'ọrụ na-akwalite ojiji nke glucose, ma na-enyere aka iwelie mmetụta nke anụ ahụ na nsonaazụ insulin. N'okwu a, metformin hydrochloride anaghị emetụta usoro nke insulin secretion site na mkpụrụ ndụ beta, n'ihi nke a na-ebelata ike nke ịmalite hypoglycemia.

Site n'enyemaka nke Formethin, enwere ike ịgwọ ụdị ọrịa shuga 2. Ọtụtụ mgbe, a na-eji ọgwụ ahụ eme ihe mgbe onye na-arịa ọrịa shuga na-arịa oke oke yana n'ọnọdụ ebe ọgwụgwọ nri anaghị enyere aka ịhazi ụkpụrụ glucose ọbara. Ọ ga-amasị m ịghọta na a na-ejikarị ọgwụ ahụ eme ihe na njikọta ọgwụ ndị metụtara ọgwụ sitere na sulfonylurea.

Kedu otu esi ewere? Usoro izizi bụ 1000-1700 mg kwa ụbọchị. Ọzọkwa, a na-ekewa usoro onyonyo ahụ ụzọ abụọ. Ọ ka mma iji ọgwụ mgbe ị risịrị nri, drinkingụọ nnukwu mmiri.

Ọ bụrụ na shuga dị n'ọbara esighị ike, mgbe ahụ ọ̀ ga-eji nwayọ rịa elu 2-3 gram kwa ụbọchị. Otutu ukwe ubochi ekwenyere ubochi obula bu gram 3, obughi kari. Ma ndị okenye ọrịa na-atụ aro ka ha ghara ịfe ihe karịrị 1 gram kwa ụbọchị.

Ihe mgbochi iji ọgwụ a:

1. Allergy na mmiri.
2. Ọrụ akụrụngwa na-arụ ọrụ, anaghị arụ ọrụ na akụrụngwa akwara.
3. Nnukwu usoro nke infarction myocardial.
4. Akpịrị ịkpọ nkụ.
5. Obi ma ọ bụ ume iku ume.
6. Ihe ọghọm nke Cerebrovascular.
7. Mmanya na-egbu egbu
8. Ime na lactation.
9. Ọnọdụ enwere ike iji insulin eme ihe. O nwere ike ịbụ nnukwu mmerụ ahụ, ọkụ ma ọ bụ ihe ịwa ahụ.
10. Lactic acidosis.
11. Nnabata na nri siri ike, nke na-enye mbelata kilogram kwa ụbọchị.
12. Ngwa n'ime ụbọchị abụọ ikpeazụ nke ọkụ-enyocha ya na iwebata ihe dị iche iche nwere ayodiin. Site n'ụzọ, ekwesighi ị consumedụ ọgwụ ụbọchị 2 tupu nyocha ahụ.

N’etiti mmetụta dị n’ị theụ ọgwụ ahụ, enwere ọghọm n’ọrụ arụ ọrụ nke mgbari nri, nsogbu nke metabolic, anaemia, hypoglycemia na mmeghachi ahụ nfụkasị. Vidio dị n’isiokwu a ga-agwa gị ụdị ọgwụ maka ọrịa shuga.