Aspikor - (Aspikor) ntuziaka maka ojiji
Ọgwụ ahụ na-egbochi ọrụ enzyme cyclooxygenase 1 na 2 (na-edozi nhazi nke prostaglandins).
Ọgwụ Aspicor nwere analgesic (analgesia), mgbochi mkpali na mmetụta antipyretic.
Ihe na - arụ ọrụ acetylsalicylic acid na - akụda usoro nke prostaglandins, n'okpuru mmetụta nke hyperalgesia na isi ihe. Mbelata nke prostaglandins na etiti ahụthermoregulation (ọkachasị E1) na-akpata mmụba ọsụsọ, mgbasa nke lumen nke arịa ọbara nke anụ ahụ, n'ihi nke a, mbelata ogo ahụ.
A na-enweta mmetụta analgesic site na njikọ aka na etiti nke ọgwụ. Nleta aspicore thromboxane A2 n'ime sel sel platelet, na-ebelata thrombosisnnabata platelet na nke ha nchịkọta.
N'ime ndị ọrịa nwere usoro angina na-akwụghị ụgwọ, Acetylsalicylic acid na-arụ ọrụ nwere ike belata ọnwụ, ihe egwu nke infarction myocardial.
Mmetụta antiplatelet na-ewe ihe dị ka otu izu mgbe ị aụsịrị otu ọgwụ.
Dailybọchị nke 6 grams ma ọ bụ karịa na-abawanye oge prothrombin, na-egbochi njikọta prothrombin n’akpụ akwara.
Pgwọ ọgwụ Aspicore na-abawanye ugboro ugboro ihe ọgbụgba dị n'ọbara.
N'okpuru mmetụta nke ọgwụ ahụ, a na-eme ka ntụpụ ahụ dị mma uric acid (n'ihi imebi tubular reabsorption na akụrụ).
Ihe ngosi maka ojiji
Edebere ọgwụ Aspicor maka enyemaka mgbu mgbu (ụdị dị nro na agafeghị oke) nke ụdị dị iche iche: migraine, isi ọwụwa, myalgiaọrịa radicular ivu oluloarthralgia lumbago, neuralgia, eze mgbu.
A na-eji ọgwụ ahụ maka ọrịa febrile megide ndabere nke ọrịa na-efe efe, mkpali.
Ihe ngbanwe
Edeghị mbadamba aspicor hemorrhagic diathesis, nwere ụdị nnabata nke acetylsalicylic acid, yana ụkwara umeji nke ụkwara ume ọkụ, na-agba ọbara site na mgbaze nri, yana mbuze na ọnya akwara nke usoro nri, na-agara ọgwụgwọ nke methotrexates, mmeme nke afọ ime (nke mbụ, nke atọ), inye nwa ara na ụmụaka ruo afọ iri na ise.
Nsonaazụ
Mpempe akwụkwọ aspicor nwere ike ibute afọ ọsịsa, ọgbụgbọ, azịza nfụkasị ụdị angioedema, ihe ọkụ anụ ahụ na bronchospasm.
Na-emegide usoro ọgwụgwọ, imebi akụrụ na sistem nke imeju ga-ekwe omume, mmepe Ọrịa Reye (imeju ngwa ngwa nke imeju, akwara dystrophy na encephalopathy), leukopenia, thrombocytopeniaoke anaemia.
Enwere ike jikọta ọgwụgwọ ogologo oge hypocoagulationọnya na ọnya ọnya nke ọnya nri, ọgbụgbọ, migraine, ọgbụgbọ, ọgba aghara,interstitial jadeọbara ọgbụgba, papillary necrosis, prezoal azotemia na hypercalcemia na hypercreatininemia, ọzịza, mụbara mgbaama nke obi ọgụ, aseptic meningitis, ụba enzymes imeju, nephrotic syndrome.
Aspicor, ntuziaka maka ojiji (Usoro na usoro onunu ogwu)
A na-eji ọnụ ede aspicor aspicor.
Na mgbu, ọrịa febrile a na-a oụ ọgwụ ahụ ruo gram 3 (nke a tụrụ aro ya bụ 0,5-1 gram kwa ụbọchị) maka usoro 3.
Dịka onye na-ahụ maka ọgwụ na ọgwụ mgbochi ọgwụ, Aspicor ka edeputara na ọgwụ nke 325 mg.
Ogologo oge ọgwụgwọ agaghị agafe izu abụọ.
A ga-ebu ụzọ gbasaa ụdị ọgwụ ọgwụ ga - agbari na mmiri mmiri 100-200. Otu ego ọgwụ ahụ bụ 0.25-1 grams (ugboro 3-4 n'ụbọchị).
Dodoụbiga ya ókè
N'ọnọdụ siri ike nke ịdoụbiga mmanya ókè, hypoglycemia, hyperventilation, coma, fever, ketoacidosis, obi na okuku ume na-ekwe omume.
Alizationnweta ụlọ ọgwụ mberede, ojiji nke unyi na-arụ ọrụ, larịị gastric, diuresis, hemodialysis, na usoro ọgwụgwọ akara.
Mmekorita
Ntụziaka maka iji Aspicore anaghị atụ aro ka iji ọgwụ eme ihe n’otu oge ya na ndị nnọchianya hypoglycemic nke onọ, acid acid, methotrexate, ndị na-egbochi antiplatelet, thrombolytics,anticoagulants na-apụtaghị ìhè, heparin, sulfonamides, antihypertensive na ndị na-ahụ maka uricosuric, diuretics.
Ihe ọghọm nke ọbara ọgbụgba na-abawanye site na iji ọgwụ ndị a na - eme n'otu oge na glucocorticosteroids na ọgwụ ethanol.
Aspikor nwere ike ime ka ịta ahụhụ nke barbiturates, digoxin, nnu nke lithium dị na plasma.
A na-ebelata nnabata nke acetylsalicylic acid n'oge ọgwụgwọ antacids.
Mmetụta hematotoxic nke Aspicore na-abawanye site na iji ọgwụ myelotoxic.
Ntụziaka pụrụ iche
Ojiji Aspikor dị ka ọgwụ mgbochi mbufụtara oke maka nnukwu ihe egwu dị na ịmalite NSAIDs-gastropathy.
Ogologo oge ọgwụgwọ agaghị karịa ụbọchị 5.
Ugbu a, a naghị enye ọgwụ ọgwụ maka ya nsogbu ụgbụụdị nfụkasị na-efe efe myocarditis, yana ọrịa ogbu na nkwonkwo na-arịa, yana ọrịa pericarditis na rheumatism.
A na-atụ aro ka achụọ Aspicor ka ọ kagbuo ụbọchị 5-7 tupu arụ ọrụ ahụ ezubere.
Ogologo oge ọgwụgwọ chọrọ mmanye nke ọnụọgụ ọbara, nyocha nke feces maka ọbara anwansi.
Ogwu a nwere ike inye Mmetụta teratogenic.
Acetylsalicylic acid dị n'ime mmiri ara ara.
Ogwu nwere ike igba ezigbo gout ọgụ.
Mpempe nnabata, nkwakọ na ngwakọta Aspicor ®
Mkpokọ mkpụrụ osisi enteric nke ọcha ma ọ bụ nke na-acha ọcha na agba, okirikiri, biconvex, na ngalaba nkebi - agbaji na-acha ọcha ma ọ bụ ụcha ọcha.
| Taabụ 1 | |
| acetylsalicylic acid | 100 mg |
Ndị pụrụ iche: microcrystalline cellulose, lactose monohydrate, sodium croscarmellose, silloon dioxide colloidal (aerosil), acid stearic.
Ngwakọta nke mkpuchi mkpụrụ osisi: copolymer nke methaclates acid na ethyl acrylate, propipylene glycol, macrogol 4000, titanium dioxide, talc.
10 PC - ngwugwu ọnya (1) - ngwugwu nke kaadiboodu.
10 PC - ngwugwu mkpọ (2) - ngwugwu nke kaadiboodu.
10 PC - ngwugwu ọnya (3) - ngwugwu nke kaadiboodu.
10 PC - ngwugwu mkpọ (6) - ngwugwu nke kaadiboodu.
20 nkp. - ngwugwu ọnya (1) - ngwugwu nke kaadiboodu.
Omume ọgwụ
NSAIDs, onye na-ahụ maka antiplatelet. Usoro nke acetylsalicylic acid dabere na mgbochi a na-edozigharị nke cyclooxygenase-1 (COX-1), n'ihi nke a enwere mgbochi nke thromboxane A 2 njikọ na mwepu nke nchịkọta platelet. A kwenyere na acetylsalicylic acid nwere usoro ndị ọzọ iji kpochapụ nchịkọta platelet, nke na-agbasa obosara ya n'ọrịa ọrịa vaskụla dị iche iche.
Acetylsalicylic acid nwekwara ọgwụ mgbochi, analgesic, mmetụta antipyretic.
Mlọ ọgwụ
Mgbe nchịkwa ọnụ gasịrị, a na-etinye acetylsalicylic acid site na obere eriri afọ nke mgbago. A na-ahụ C max na plasma na nkezi awa 3 mgbe ị ofụ ọgwụ ọjọọ gasịrị.
Acetylsalicylic acid na-enwe metabolism dị ala na imeju na ịmalite nke metabolites na-adịchaghị arụ ọrụ.
Ọ bụ ya bụ akụrụ, ma ndị na-agbanweghi agbanwe yana metabolites. Acetylsalicylic acid T 1/2 dị ihe dị ka minit 15, maka metabolites - ihe dị ka awa 3
Na-egosi Aspikor ®
- mgbochi nke nnukwu myocardial infarction na ọnụnọ ihe ndị dị ize ndụ (dịka ọmụmaatụ, ọrịa shuga mellitus, hyperlipidemia, ọbara mgbali elu, oke ibu, ị smokingụ sịga, ịka nká),
- mgbochi nke ịda infịction nke myocardial ugboro ugboro,
- angina enweghi ike,
- Mgbu ọrịa strok (gụnyere na ndị ọrịa nwere ọrịa ọrịa ụkwara ume ọkụ),,
- mgbochi nke ọghọm ụbụrụ ụbụrụ,
- mgbochi nke thromboembolism mgbe ịwa ahụ na ọgwụ ndị na-emetụta mmụọ (dịka ọmụmaatụ, akwara akwara akwara enyocha ya, akwara artisiovenous shunting, carotid artery angioplasty),
- mgbochi nke thrombosis miri emi na thromboembolism nke akụkụ akwara umeji yana alaka ya (dịka ọmụmaatụ, ya na ịgbatị ogologo oge n'ihi oke ịwa ahụ).
| Koodu ICD-10 | Ngosipụta |
| G45 | Ọrịa ọgbụgba na-adị obere oge na ọgụ ọgụ na syndromes ndị metụtara ya |
| I20.0 | Angina na-ejighi |
| I21 | Nnukwu myocardial infarction |
| I26 | Emulisi nke pulmonary |
| I61 | Ọbara ọbara intracerebral (ụdị ọria ụbara nke ụbara) |
| I63 | Ngwunye ụbụrụ |
| I74 | Embolism na thrombosis akwara |
| I82 | Embolism na thrombosis nke veins ndị ọzọ |
Usoro usoro onunu ogwu
E kwesịrị iji mbadamba ọnụ, tupu nri, yana ọtụtụ mmiri.
Mgbochi nke myocardial infarction na-egbu egbu: 100-200 mg / ụbọchị (a ga-ata ata mbadamba nkume mbụ maka njikwa ngwa ngwa).
Mgbochi nke nnukwu myocardial infarction na ọnụnọ nke ihe ndị dị ize ndụ: 100 mg / ụbọchị.
Mgbochi nke infarction myocardial ugboro ugboro, angina na-ejighị n'aka, mgbochi nke ọrịa strok na ihe mberede cerebrovascular, igbochi nsogbu nke thromboembolic mgbe ịwa ahụ ma ọ bụ ọmụmụ mmerụ ahụ: 100-300 mg / ụbọchị.
Mgbochi nke thrombosis nke miri emi na thromboembolism nke akwara ọbara na alaka ya: 100-200 mg / ụbọchị.
O bu n'uche ogwu a ka o jiri ogologo oge. Ọ bụ dibia bekee gara kpebie oge ọgwụgwọ ahụ.
Mmetụta akụkụ
Site na nri digestive: ọgbụgbọ, obi mgbawa, ọgbụgbọ, mgbu ke afo, ọnya afọ nke mucous akpụkpọ ahụ na duodenum (gụnyere perforated), ọbara ọgbụgba, ibu ọrụ nke enzymes imeju.
Site na sistem iku ume: akwara ozi.
Site na sistemụ hemopoietic: ọbara ọgbụgba hiri nne, adịkarịghị - anaemia.
Site n'akụkụ nke usoro ụjọ ahụ: dizziness, tinnitus.
Mmeghachi omume nfụkasị: urticaria, edema nke Quincke, mmeghachi omume anaphylactic.
Ime na lactation
Ojiji nke salicylates na usoro onyonyo dị elu n'ime ọnwa atọ mbụ nke afọ ime nwere ihe jikọrọ ya na ọtụtụ ugboro nke ntụpọ nwa ebu n’afọ (ogwe nke kewara, obi obi). N'ime oge nke abụọ nke afọ ime, a ga-enye salilylates naanị na nyocha dị omimi banyere ihe ọghọm na uru.
N'ime oge nke atọ nke afọ ime, salicylates na oke ọnụọgụ (karịa 300 mg / ụbọchị) na-ebute mgbochi nke ọrụ, mmechi akwara nke ductus arteriosus na nwa ebu n’afọ, ọbara ọgbụgba n’ime nne na nwa n’afọ, na nchịkwa ozugbo tupu amụọ nwa nwere ike ibute ọbara ọgbụgba intracranial, ọkachasị n’oge ụmụ akatabeghị aka. Nkwekọrịta nke salicylates na nke atọ ọnwa atọ dị ime tụpụtara.
Salicylates na metabolites ha n'ime obere, na-apụ apụ na mmiri ara. Usoro a na-anabatakarị nke salicylates n'oge a na-enye nwa na-esoghị mmepe mmeghachi omume ọjọọ na nwatakịrị ahụ anaghị achọ ịkwụsị ị ofụ ara. Agbanyeghị, ọ bụrụ na ịchọrọ iji ọgwụ ogologo oge ma ọ bụ nhọpụta nke oke ị ,ụ mmiri, a ga-akwụsị inye nwa ara ozugbo.
Mkparịta ụka ọgwụ ọjọọ
Site n'iji acetylsalicylic acid na-akwalite ihe nke ọgwụ ndị na-esonụ:
- methotrexate site na mbenata nhichapụ mkpụ ya na iwepụ ya na nkwukọrịta na protein.
- heparin na anticoagulants na-adịghị mma n'ihi ọrụ platelet na-adịghị arụ ọrụ na nchụpụ nke anticoagulants na-apụ apụ na mkparịta ụka na protein.
- ọgwụ thrombolytic na antiplatelet (ticlopidine),
- digoxin n'ihi mbelata akwara izizi ya,
- ndị nnọchi hypoglycemic (insulin na usoro sulfonylurea) n'ihi hypoglycemic Njirimara nke acetylsalicylic acid n'onwe ya na oke ọnụọgụ na mbufụt nke ihe ndị na-emepụta sulfonylurea site na nkwukọrịta na protein.
- valproic acid n'ihi mbupụ ya na mkparịta ụka na protein.
A na-ahụta mgbakwunye mmetụta mgbe ị na-ewere acetylsalicylic acid na ethanol.
Acetylsalicylic acid na-ebelata mmetụta nke ọgwụ uricosuric (benzbromarone) n'ihi tubular asọmpi ikpochapụ uric acid.
Site na ịkwalite mkpocha nke salicylates, systemic corticosteroids na-ebelata mmetụta ha.
VERTEX AO (Russia)
199106 St. Petersburg Aspikard (BORISOVA OFR OF ỌR M ọgwụ ọgwụ, Republic of Belarus) Aspinat ® (VALENTA PHARMACEUTICS, Russia) Aspinat ® Cardio (VALENTA PHARMACEUTICS, Russia) Aspirin ® Cardio (Onye na-ahụ maka ụbọchị BAYER, Switzerland) Acetylcardio-LekT (TYUMEN CHEMICAL - PHARMACEUTICAL PLANT, Russia) Mwepụta wepụtara ya na ihe mejupụtaraA na-emepụta aspicore n'ụdị mbadamba mkpụrụ osisi na-acha ọbara ọbara: ihe fọrọ nke nta ka ọ bụrụ ọcha ma ọ bụ na-acha ọcha, biconvex, okirikiri, n'akụkụ nke obe - ụdị nke fọrọ nke nta ka ọ bụrụ nke na-acha ọcha ma ọ bụ na-acha ọcha (PC 10. Ngwugwu 6, ngwugwu 15. Nke ọ bụla n'ime ngwugwu nwere agba, na paịlị 2 ma ọ bụ 4 ngwugwu, ngwugwu 20. N'ime ngwugwu na-acha uhie uhie, na ngwugwu kaadi paịlị 1 ma ọ bụ 3, pọọsụ 30. ) Ngwakọta 1 mbadamba:
Usoro onunu ogwu na nhaziA na-ewere aspikor n'ọnụ, tupu nri, ekwesịrị iji mmiri dị ukwuu tabletsachapụ mbadamba nkume. O bu ogwu a ka eji eme ogologo, ndi okacha mara ka edobere ya. N'ime ọgwụgwọ angina na-akwụghị chịm, Aspicor na-eji mbadamba 1-3 (100-300 mg) kwa ụbọchị. Iji gbochie ọgwụ a na-atụ aro ka a ga-ewere ya na usoro ndị a kwa ụbọchị:
Aspicore, ntuziaka maka ojiji: usoro na usoro onunu ogwuA ga-eburịrị mbadamba ọgwụ aspicore tupu nri, yana ọtụtụ mmiri. Na-atụ aro onunu ogwu kwa ụbọchị:
Aspikor ezubere maka ọgwụgwọ ogologo oge, nke dọkịta na-ahụ maka ịga kpebiri kpebie oge ọ ga-eji mee ihe. Ime na lactation
Aspicore: ọnụ ahịa dị na ahịa ọgwụ dị n'ịntanetịMbadamba ụrọ aspicore 100 mg 30 pcs. ASPICOR 100mg 30 PC. mbadamba osisi nke etinyere n’ime Aspicor Tab. .p / o ihe nkiri. enteric. 100mg n30 ASPICOR 100mg 90 pcs. mbadamba osisi nke etinyere n’ime Aspicor Tab. n / a ksh / sol. 100mg Nke 90 Mpekere 100pị siri ike aspicore 90 pcs.
Mmụta: Universitylọ akwụkwọ Mahadum Medical Ahụike Moscow nke mbụ aha ya bụ I.M. Sechenov, ọpụrụiche "General Medicine". A na-emejupụta ozi gbasara ọgwụ a, enyere ya aka maka ihe ọmuma ma ọ doghị ntuziaka ndị isi. Medication medicationụ onwe gị ọgwụ dị ize ndụ nye ahụ ike! Ọrụ mmadụ na-enweghị mmasị na ya bụ ihe na-emebi mmụọ ya karịa enweghị ọrụ ma ọlị. Dabere na ọmụmụ, ụmụ nwanyị ndị na-a severalụ ọtụtụ iko biya ma ọ bụ mmanya n'izu, ha nwere ohere dị ukwuu nke ịrịa ọrịa cancer ara. Nwa nwoke onye Australia dị afọ 74, James Harrison ghọrọ onye na-enye ọbara n'ihe dị ka 1,000 ugboro. O nwere ụdị ọbara dị ụkọ, ọgwụ mgbochi nke enyere ụmụ amụrụ ọhụrụ aka na-arịa oke anaemia. N'ihi ya, onye Australia chebere ihe ruru ụmụaka nde abụọ. Dabere na ọtụtụ ndị ọkà mmụta sayensị, usoro ihe ọmụmụ vitamin abaghị uru ụmụ mmadụ. N'oge ịsụgharị, ahụ anyị na-akwụsị ịrụ ọrụ kpamkpam. Ọbụna obi na-akwụsị. N'oge ndụ, nkezi onye na-amịpụta obere mmiri mmiri abụọ. Ọ na-emebu ikuku ahụ na-eme ka ahụ nwee ikuku oxygen. Kaosiladị, echiche a gbagọrọ agbagọ. Ndị sayensị achọpụtala na mgbagharị, mmadụ na-eme ka ụbụrụ dị jụụ ma na-eme ka arụmọrụ ya ka mma. Mgbe ị na-arụ ọrụ, ụbụrụ anyị na-etinye ike lara nha nke 10-watt lightb. Yabụ na onyinyo nke oriọna dị n’elu isi gị n’oge ngosipụta nke echiche na-adọrọ mmasị adịghị anya n’eziokwu. O buru na inyinya inyinya, ino karie igha olu gi karia ka inwere n’agha. Naanị anwala igosipụta nkwupụta a. Iji mee ka onye ọrịa pụọ, ndị dọkịta na-agakarị ngabiga. Dịka ọmụmaatụ, ụfọdụ Charles Jensen na oge site na 1954 ruo 1994. lanarịrị ihe karịrị 900 neoplasm n'ọrụ mwepụ. Onye na-a antụ ọgwụ mgbochi n’oge ikpe ga-enwetakwa ịda mbà n’obi ọzọ. Ọ bụrụ na mmadụ anagide nkụda mmụọ na aka ya, ọ nwere ohere ọ bụla ichefu ọnọdụ a ruo mgbe ebighi ebi. Ọ bụrụgodi na obi mmadụ adịghị akụ aka, mgbe ahụ ọ ka nwere ike ibi ndụ ogologo oge, dịka onye ọkụ azụ na Norway bụ Jan Revsdal gosiri anyị. ““ Moto ”ya kwụsịrị ruo awa anọ mgbe onye ọkụ azụ̀ ahụ furu ụra ma daa n'ụra snow. E bugara ọtụtụ ọgwụ ka ọ bụrụ ọgwụ. Dịka ọmụmaatụ, azara ahịa Heroin na mbụ ka ọ bụrụ ọgwụ ụkwara. A na-atụkwa ọgwụ cocaine ka ọgwụ na-eme ka ọgwụ na-egbu egbu ma bụrụkwa ụzọ iji nwekwuo ntachi obi. E dere temprechọ kachasị elu na Willie Jones (USA), onye nabatara n'ụlọ ọgwụ ahụ na-enwe 46.5 Celsius. Imeju bụ akwara kacha anyị n’ahụ. Ogo ya di 1.5 n'arọ. A ma mmanụ azụ azụ kemgbe ọtụtụ iri afọ, n'oge a, egosiputala na ọ na - enyere aka belata mbufụt, belata nkwonkwo mgbu, na - emeziwanye sos.
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